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11 results on '"Aleksandrovich, Yuriy S."'

2. Determination of Risk Factors for Severe Life-Threatening Course of Multisystem Inflammatory Syndrome Associated with COVID-19 in Children

Author

Avrusin, Ilia S., primary, Abramova, Natalia N., additional, Belozerov, Konstantin E., additional, Kondratiev, Gleb V., additional, Bregel, Liudmila V., additional, Efremova, Olesya S., additional, Vilnits, Alla A., additional, Konstantinova, Julia E., additional, Isupova, Eugenia A., additional, Kornishina, Tatiana L., additional, Masalova, Vera V., additional, Felker, Eugeniy Yu., additional, Kalashnikova, Olga V., additional, Chasnyk, Vyacheslav G., additional, Aleksandrovich, Yuriy S., additional, and Kostik, Mikhail M., additional

Published
2023
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3. Using HScore for Evaluation of Hemophagocytosis in Multisystem Inflammatory Syndrome Associated with COVID-19 in Children.

Author

Avrusin, Ilia S., Abramova, Natalia N., Belozerov, Konstantin E., Bregel, Liudmila V., Efremova, Olesya S., Vilnits, Alla A., Konstantinova, Julia E., Isupova, Eugenia A., Kornishina, Tatiana L., Masalova, Vera V., Kalashnikova, Olga V., Chasnyk, Vyacheslav G., Aleksandrovich, Yuriy S., Ivanov, Dmitri O., and Kostik, Mikhail M.

Subjects
MULTISYSTEM inflammatory syndrome, BLOOD sedimentation, MULTISYSTEM inflammatory syndrome in children, ASPIRIN, COVID-19, HAND-foot syndrome, MYELOFIBROSIS
Abstract

Hemophagocytic syndrome is a key point in the pathogenesis of severe forms of multisystem inflammatory syndrome associated with COVID-19 in children (MIS-C). The factors associated with hemophagocytosis in patients with MIS-C were assessed in the present study of 94 boys and 64 girls ranging in age from 4 months to 17 years, each of whose HScore was calculated. In accordance with a previous analysis, patients with HScore ≤ 91 (n = 79) and HScore > 91 (n = 79) were compared. Patients with HScore > 91 had a higher frequency of symptoms such as cervical lymphadenopathy, dry cracked lips, bright mucous, erythema/swelling of hands and feet, peeling of fingers, edematous syndrome, hepatomegaly, splenomegaly, and hypotension/shock. They also had a higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and D-dimer levels, and a tendency to anemia, thrombocytopenia, and hypofibrinogenemia. They more often needed acetylsalicylic acid and biological treatment and were admitted to ICU in 70.9% of cases. Conclusion: The following signs of severe MIS-C were associated with HScore > 91: myocardial involvement, pericarditis, hypotension/shock, and ICU admission. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Acute methadone poisoning in infants

Author

Udaltcov, Maksim A., primary, Pshenisnov, Konstantin V., additional, Aleksandrovich, Yuriy S., additional, Kaziakhmedov, Vitaliy A., additional, Pochinyaeva, Lyubov M., additional, and Storozhuk, Olga D., additional

Published
2020
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