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Abstract Background Anaplastic large-cell lymphoma primarily involving the omentum is an extremely rare entity with variable clinical presentation. Owing to its rarity and nonspecific clinical manifestation, omental T-cell lymphoma is often diagnosed at a later stage, riddled with complications. While imaging modalities such as computed tomography scan can help a physician reach a diagnosis, cases that present with complications may require a multidisciplinary approach that combines surgical exploration along with consultation from Oncology. Case presentation We hereby report a rare case of a 66-year-old African American male patient who presented to the emergency department with complaints of acute gastrointestinal obstruction. A computed tomography scan of the abdomen and pelvis revealed evidence of an internal hernia and surgical exploration revealed a hemorrhagic and infarcted omentum. Biopsies along with immunophenotypic studies confirmed the diagnosis of anaplastic T-cell lymphoma of the omentum complicated by Massilia timonae infection. Conclusion The case highlights the significance of considering lymphoma, although rare, as a differential in a patient who presents with small bowel obstruction and the importance of investigating for malignancy for early diagnosis and treatment of primary omental lymphomas, before complications develop.

The current study examines the flow characteristics under free flow conditions over a crump weir. The impact of the side slopes of the weir on the coefficient of discharge (Cd) is taken into account. Four physical models with crest heights of 0.15 m under free flow circumstances and four upstream side slope (1:3, 1:2.5, 1:2 and 1:1.5) were used to investigate the impact of various variables on discharge coefficient (Cd). Using the dimensional analysis technique, the elements influencing the crump weir's discharge coefficient were determined based on laboratory tests. For the same flow rate, Cd value decrease by decreasing upstream side slope. It notices that a decrease in upstream slope (from 1:3 to 1:2.5) reducing Cd value about (2.61 %), decrease upstream slope from (1:3 to 1:2) reducing Cd value about (4.16 %) and when decrease upstream slope from (1:3 to 1:1.5) reducing Cd value about (5.81 %).

Abstract Background It is challenging to predict long-term outcomes of interventions without understanding how they work. Health economic models of public health interventions often do not incorporate the many determinants of individual and population behaviours that influence long term effectiveness. The aim of this paper is to draw on psychology, sociology, behavioural economics, complexity science and health economics to: (a) develop a toolbox of methods for incorporating the influences on behaviour into public health economic models (PHEM-B); and (b) set out a research agenda for health economic modellers and behavioural/ social scientists to further advance methods to better inform public health policy decisions. Methods A core multidisciplinary group developed a preliminary toolbox from a published review of the literature and tested this conceptually using a case study of a diabetes prevention simulation. The core group was augmented by a much wider group that covered a broader range of multidisciplinary expertise. We used a consensus method to gain agreement of the PHEM-B toolbox. This included a one-day workshop and subsequent reviews of the toolbox. Results The PHEM-B toolbox sets out 12 methods which can be used in different combinations to incorporate influences on behaviours into public health economic models: collaborations between modellers and behavioural scientists, literature reviewing, application of the Behaviour Change Intervention Ontology, systems mapping, agent-based modelling, differential equation modelling, social network analysis, geographical information systems, discrete event simulation, theory-informed statistical and econometric analyses, expert elicitation, and qualitative research/process tracing. For each method, we provide a description with key references, an expert consensus on the circumstances when they could be used, and the resources required. Conclusions This is the first attempt to rigorously and coherently propose methods to incorporate the influences on behaviour into health economic models of public health interventions. It may not always be feasible or necessary to model the influences on behaviour explicitly, but it is essential to develop an understanding of the key influences. Changing behaviour and maintaining that behaviour change could have different influences; thus, there could be benefits in modelling these separately. Future research is needed to develop, collaboratively with behavioural scientists, a suite of more robust health economic models of health-related behaviours, reported transparently, including coding, which would allow model reuse and adaptation.

OBJECTIVE: To investigate the hepatoprotective effects of Unacylated Ghrelin (UAG) at varying doses in the management of acute liver injury in Wistar albino rats. METHODS: This quasi-experimental study was conducted at Department of Physiology, Isra University, Hyderabad, Pakistan from March to August 2023. Thirty Wistar albino rats (200-250 grams) were randomly divided into five groups (n=6). Group A served as the control, while liver injury was induced in Groups B, C, D, and E via intraperitoneal injection of 0.1% CCl₄. Groups C, D, and E were subsequently treated with low, medium, and high doses of UAG, respectively. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), malondialdehyde, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and superoxide dismutase (SOD) levels were assessed, along with liver histopathology. RESULTS: Pre-experimental body weights (Mean±SD) for groups A, B, C, D, and E were 227.33±7.75 g, 229.80±2.08 g, 228.70±5.34 g, 231.33±8.69 g, and 236.38±10.63 g, respectively. The liver index was 4.36±0.28, 6.65±0.37, 5.80±0.17, 5.70±0.08, and 5.06±0.23, respectively, across the groups. A statistically significant (p

Objectives: The general concern about low back pain (LBP) necessitates thoroughly examining its various causes and feasible therapies. The current study investigated the causes and surgical treatments of back pain by tailoring treatments to the patient’s specific needs. Methods: Two hundred individuals with LBP have been enrolled in this cross-sectional research. The radiological, magnetic resonance imaging (MRI) images and clinical evaluations were completed by neurosurgeons and used to categorize the selected patients from those attending neurosurgical outpatient clinics. Multiple causes of LBP, including disk prolapse, spinal stenosis, and muscular spasms, were investigated. Detailed descriptions of surgical approaches for various stages of disk prolapse and stenosis were given to help decide the optimal surgical tactics. The data were compiled into an Excel sheet, and the percentages and numbers were sorted and computed appropriately. Results: The data present an extensive overview of the distribution pattern of back pain causes, disk prolapse, and spinal stenosis in the study community, along with the surgical procedures employed. Muscle spasms, disk prolapse, and spinal stenosis are the main causes of back pain (20%, 40%, and 13%, respectively). L5 and S1 are the most commonly involved in single-level disk prolapse (10%). Different spinal levels may have varying percentages of multiple-level disk prolapse (20%). There are multiple lumbar levels where spinal stenosis can occur, but the most common are L4 and L5 (20%). Distinct surgical approaches are employed for disk prolapse and stenosis at various levels of the spine, and the most frequent intervention was laminectomy in about 39% of total participants. Discussion: The study’s results demonstrate the complexity of the etiologies of back pain and the need for advanced surgical techniques. Particular emphasis is concentrated on spinal stenosis, including single- and multiple-level disk prolapse, and the relationship between surgical methods and causes. The study’s thorough comprehension is essential for tailored interventions based on patient traits, ultimately enhancing therapy and patient care.

Abstract Introduction and importance Choledochal cysts are congenital conditions that affect the biliary tree, typically identified during childhood. These cysts present as dilations in the biliary system, occurring either in the extrahepatic or intrahepatic regions or in some cases, in both areas. Occasionally, it may have associated chronic pancreatitis posing a challenge to the management of both conditions. In the case reported, a female child was diagnosed with a choledochal cyst along with chronic pancreatitis. She had an excision of cyst and lateral pancreaticojejunostomy simultaneously for both conditions resulting in favorable outcomes. Case presentation An 8-year-old child visited the clinic with a complaint of upper abdominal pain accompanied by intermittent vomiting. An ultrasound was performed which showed a dilated common bile duct. To confirm the diagnosis, an MRCP and baseline labs including liver function tests were ordered. The findings were suggestive of a type IA choledochal cyst with concomitant chronic pancreatitis. Subsequently, she had choledochal cyst excision with Roux-en-Y hepaticojejunostomy reconstruction plus lateral pancreaticojejunostomy using the classical Puestow’s technique. The patient’s recovery post-surgery was uneventful, resulting in discharge on the fifth post-operative day for routine outpatient follow-up. Clinical discussion Patients afflicted with choledochal cysts are prone to recurrent pancreatitis, though the precise underlying mechanism is unknown. Certain studies propose an association between abnormal pancreatico-biliary junction and recurrent pancreatitis, often defined as a common channel surpassing 15 mm in length. However, this aberration could not be definitively established in the current case. Diagnosis of choledochal cysts can be confirmed through either ERCP or MRCP, with the latter preferred due to its non-invasive nature. The optimal management strategy for choledochal cysts necessitates cyst resection and Roux-en-Y hepaticojejunostomy reconstruction Moreover, in cases associated with chronic pancreatitis, longitudinal pancreatojejunostomy may be undertaken. Conclusion Thus, it is concluded that although rare choledochal cysts may have associated chronic pancreatitis. Surgical excision of the cyst and lateral pancreaticojejunostomy can be performed simultaneously resulting in favorable post-operative outcomes.

Background: Infertility affects married adults, and In Vitro Fertilization (IVF) is an Assisted Reproductive Technology (ART) that can treat it. Women undergoing IVF are more likely to experience depression. There is a need to reduce depression by supporting and advising sufferers. The aim of this study is to evaluate the effect of depression on pregnancy rates among infertile females underwent IVF treatment. Materials and Methods: This observational study analyzed 149 patients attending the infertility center at Kamal Al-Samaraie hospital seeking a chance of a conception. The participants received a traditional hospital protocol. The study assessed depression status using the CES-D (Center for Epidemiologic Studies Depression) scale at the beginning of the IVF cycle. Results: Conclusion: Our findings show that the pregnancy rate was not related to baseline depression of women underwent the first IVF procedure. .

Concrete 3D printing is a promising manufacturing technology for producing geometrically complex structures efficiently and cost-effectively, by eliminating the need for formwork, reducing labor, and minimizing waste. This method has the potential to lower carbon emissions and resource use. However, it does not mitigate the carbon emissions associated with cement production. Nonetheless, utilizing waste materials in concrete 3D printing may reduce concrete carbon emissions and support recycling. This study investigates the use of two industrial waste materials–fly ash (FA) and ground waste glass (GWG)–as partial substitutes for ordinary Portland Cement (PC) in 3D printable cement paste. The chemical composition, particle size distribution, rheological properties, and flexural strength of the mixtures were analyzed. Results show that specimens containing waste materials achieved strengths comparable to traditional cement mixtures. The flexural strength reduction in 3D printed versus cast specimens varied across mixtures: control (66% reduction), FA20 (35%), FA10-GWG10 (35%), GWG10 (32%), FA10 (11%), and GWG20 (4%). Hence, incorporating waste materials in concrete 3D printing is recommended, as it maintains mechanical integrity while promoting recycling and upcycling of industrial waste.

Background: This study aimed to examine the efficacy of methylene blue (MB) and toluidine blue O (TBO) photodynamic therapy (PDT) as adjuncts to root surface debridement (RSD). Methods: This split-mouth, randomized, controlled clinical trial included eighteen patients, and a total of 332 sites (control = 102, MB = 124 and TBO = 106) were examined. Two sessions of PDT were completed at baseline and two weeks after RSD. Clinical parameters of bleeding on probing (BOP), plaque index (PI), probing pocket depth (PPD), and clinical attachment level (CAL) were measured pre- and post-treatment. Results: PPD and BOP reductions in sites treated by RSD with adjunctive photosensitizers (MB and TBO) were significantly higher than in control sites. RSD with MB showed higher efficacy in improving moderately deep pockets (OR 3.350), while adjunctive TBO showed better results in treating deeper pockets (OR 4.643). Conclusions: Results suggested that adjunctive use of MB and TBO to RSD could significantly improve periodontal pocket closure and reduce signs of inflammation. In addition, TBO seems to be more efficient in treating deep periodontal pockets than MB, which is more effective in resolving shallower pockets.

Abstract Major depressive disorder (MDD) is accompanied by activated neuro-immune pathways, increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The most severe MDD phenotype, namely major dysmood disorder (MDMD), is associated with adverse childhood experiences (ACEs) and negative life events (NLEs) which induce cytokines/chemokines/growth factors. To delineate the impact of ACE + NLEs on physiosomatic and FF symptoms in first episode (FE)-MDMD, and examine whether these effects are mediated by immune profiles. ACEs, NLEs, physiosomatic and FF symptoms, and 48 cytokines/chemokines/growth factors were measured in 64 FE-MDMD patients and 32 normal controls. Physiosomatic, FF and gastro-intestinal symptoms belong to the same factor as depression, anxiety, melancholia, and insomnia. The first factor extracted from these seven domains is labeled the physio-affective phenome of depression. A part (59.0%) of the variance in physiosomatic symptoms is explained by the independent effects of interleukin (IL)-16 and IL-8 (positively), CCL3 and IL-1 receptor antagonist (inversely correlated). A part (46.5%) of the variance in physiosomatic (59.0%) symptoms is explained by the independent effects of interleukin (IL)-16, TNF-related apoptosis-inducing ligand (TRAIL) (positively) and combined activities of negative immunoregulatory cytokines (inversely associated). Partial least squares analysis shows that ACE + NLEs exert a substantial influence on the physio-affective phenome which are partly mediated by an immune network composed of interleukin-16, CCL27, TRAIL, macrophage-colony stimulating factor, and stem cell growth factor. The physiosomatic and FF symptoms of FE-MDMD are partly caused by immune-associated neurotoxicity due to T helper (Th)-1 polarization and M1 macrophage activation and relative lowered compensatory immunoregulatory protection.

Objective: To determine the sensitivity, specificity, and diagnostic accuracy of the Sequential Organ Failure Assessment score in predicting one-month mortality in patients requiring critical care. Study Design: Cross-sectional validation study. Place and Duration of Study: Department of Surgery, Combined Military Hospital, Rawalpindi, Pakistan Apr to Oct 2020. Methodology: This study was conducted on 173 patients requiring intensive care. All patients aged between 20 and 70 years diagnosed with disorders secondary to traumatic causes or otherwise who were admitted for critical care were included. Patients were assessed at the time of admission to the intensive care unit, and their Sequential Organ Failure Assessment scores were calculated. A cut-off level of ≥7 was considered to be a high risk for mortality within thirty days of admission. All patients were followed up for thirty days for the mortality. Results: Mean age of our patients was 43.04±11.26 years, of whom 109(60.6%) patients were male. A SOFA score of ≥7 in predicting the mortality within thirty days of admission for critical care carried a sensitivity of 31.40%, a specificity of 25.53%, a positive predictive value of 27.84%, a negative predictive value of 28.92% and a diagnostic accuracy of 28.33%. Conclusion: The Sequential Organ Failure Assessment score lacks the diagnostic accuracy to precisely predict the mortality in critically ill patients within thirty days of developing the requirement for critical care.

BackgroundOver the last decade, there has been an increase in the evidence base supporting the efficacy of video consultations (VCs) in mental health services. Furthermore, the potential of VC treatment was also demonstrated during the COVID-19 pandemic. Despite these promising results and conducive conditions for VCs, several studies have highlighted that the uptake and implementation of VCs continues to be slow, even after the pandemic. To facilitate and strengthen the implementation of VCs and exploit their potential as a useful tool for mental health disorder treatment, there is a need for a deeper understanding of the issues and experiences of implementing and using VCs as a treatment modality in clinical practice. ObjectiveThe aim of this study was to investigate patients’ and clinicians’ experiences and attitudes toward using VCs in clinical practice. MethodsTreatment was conducted through the VC modality. Semistructured interviews were conducted individually with patients (n=10) and focus group interview were conducted with clinicians (n=4). Patients had participated in weekly VC treatment over 2 months as part of mental health outpatient services in Denmark. Data from these interviews were analyzed using thematic analysis. ResultsThematic analysis of the patient interviews yielded two main themes: (1) adjusting to the practicalities of the VC format and (2) the practice of therapy using VCs. Patients experienced that using VCs was easy and convenient, and it was possible to establish and maintain a therapeutic alliance. They also described the contact as different to in-person therapy. The thematic analysis conducted on clinicians’ experiences of using VCs yielded three themes: (1) a shift in mindset from resistance to acceptance, (2) the contact is different when using the VC modality, and (3) adapting to a new way of working. Clinicians experienced that their initial concerns and resistance toward VC implementation gradually diminished over time as they gained clinical experience of using the modality. They expressed that contact with patients can be different when using the VC modality and that it took time to adjust to a new way of working therapeutically. ConclusionsBoth patients and clinicians experienced that VCs could enhance access to treatment and be meaningfully integrated into clinical practice. In addition, both groups described the contact when using the VC modality as being different to in-person therapy. Future research could examine patients’ and clinicians’ perceived differences regarding contact when using the VC modality and the implications for therapeutic interventions.

This study reports the comparative evaluation of yield, physico-chemical composition and biological attributes (antioxidant activity, antimicrobial activity, biofilm inhibition and hemolytic activity) of peppermint (Mentha piperita L.) essential oil (EO) obtained by hydro-distillation (HD) and supercritical fluid (CO2) extraction (SCFE) methods. The yield (%) of EO obtained by HD (0.20 %) was significantly (p

Post-combustion carbon capture (PCC) technique has been extensively investigated over the past two decades to mitigate the effects of greenhouse gas (GHG) emissions. Nowadays, integrating solar energy with a PCC retrofit has become an active area of research due to its potential to slash the energy penalty on power plants. The economic aspects of both solar-assisted PCC (SA-PCC) and solar-powered PCC (SP-PCC) counterparts have already been studied in literature. Therefore, this paper aims at analysing and comparing the environmental footprints of SA-PCC and SP-PCC systems throughout their life cycle using the ReCiPe 2016 method. A cradle-to-grave framework is employed to specify the life cycle inventories in OpenLCA software for capturing one carbon capture unit (tonne of CO2) over the project’s lifespan. Results showed that SP-PCC significantly reduces environmental burdens (>10%) in various midpoint categories compared to SA-PCC counterpart. Furthermore, the endpoint assessment of SA-PCC revealed that particulate matter formation, global warming, land use, and mineral scarcity have substantial damaging impacts on the endpoint areas of protection, accounting for 37.29%, 49.48%, 76.18%, and 13.49% of the total impact, respectively. As a result, they are classified as critical impact categories that should receive priority attention for improvements. Further categorization of critical categories showed that the key difference between the examined systems lies in the contributions of nitrate salts and mono-ethanolamine (MEA) production. Furthermore, MEA contributions in SP-PCC are considerably lower than those of nitrate salts in SA-PCC across the critical categories. This demonstrates the superiority of SP-PCC over the SA-PCC in mitigating the environmental burdens when incorporating solar energy in carbon capture process

Background: Mandibular fracture is one of the commonest facial skeletal injuries, the classical treatment for condylar fracture either by close or open reduction. The purpose of this study is to prove the effectiveness of early functional rehabilitation through the effect of neuromuscular adaptation in unilateral and bilateral condylar fractures . Patients and Methods: A prospective study included thirty patients presenting with condylar fractures, divided into three age groups , group I children less than 12 years old , group II teenagers age range 12-17 years old and group III adult more than 17 years those admitted to maxillofacial department in Al-Basra Teaching Hospital from May,1,2015 until October,30,2016 presented with a malocclusion, a deviated midline, and a limited mouth opening. Computed Tomography is done as early as possible. The method used in our study was the early closed active functional treatment. Results: Young patients less than 12 years of age were 17 (56.7%), also we found that the dislocation of condylar head fracture was more common in the very young age group according to the CT- Scan. Teenagers patients (12-17) years of age were 2 (6.7%) while adult patients more than 17 years old were 11 (36.7%) . Conclusion:The complete condylar remodeling (restitution of condylar head) occurs in very young age group (less than 12 years old) and to less extent in others age groups , the diagnosis depend on ct scan findings in pre and post imaging .

Abstract Background Anaplasma ovis (A. ovis) is the predominant causative agent of anaplasmosis in goats and sheep in most tropical and subtropical regions of the world. However, there is considerable variation in reported infection rates, breed susceptibility, and controversial findings regarding the haemolytic effects of A. ovis infection in goats. Objectives Thus, we investigated the molecular and haematological aspects of A. ovis infection in goats from Ahvaz city. Methods One hundred and fifty apparently healthy goats (74 blacks and 76 Najdi goats) were randomly sampled from six flocks in the Ahvaz suburb during ticks’ activity season. Haematological evaluation, smear microscopic (SM) examination and PCR assay were performed to assess A. ovis infection. Additionally, the percentage of parasitemia was determined from blood smears. Results SM examination revealed that 25.7% of the goats displayed erythrocyte Anaplasma‐like inclusion bodies. PCR analysis indicated that 54% of the goats were positive for A. ovis infection (44.6% of blacks and 63.2% of Najdi goats). No significant difference in haematological values was observed between healthy and infected goats based on PCR testing. However, a significant difference in haematological indices was observed between the group with parasitemia level of 0.01–0.02% (SM and PCR positive) compared to the healthy goats (SM and PCR negative), particularly concerning Hb, PCV and RBC count (p < 0.01). Conclusions When the parasitemia exceeds 0.01%, A. ovis infection may disrupt haematological parameters in infected goats. The high prevalence of A. ovis infection (54%) among the studied goats underscores the importance of giving special attention to implementing necessary measures for disease control in the Ahvaz suburb.

Abstract The Himalaya, Kohistan, and Karakoram ranges comprise Proterozoic to Cenozoic crystalline complexes exposed in northern Pakistan. Numerous hot springs in the area indicate high subsurface temperatures, prompting a need to evaluate the local contribution of radiogenic heat to the general orogenic-related elevated geothermal gradients. The current study employed a portable gamma spectrometer to estimate the in-situ radiogenic heat production in the Nanga Parbat Massif, Kohistan–Ladakh batholith, and the Karakoram batholith. Heat production in the Nanga Parbat Massif is high, with a range from 0.2 to 10.8 µWm−3 and mean values of 4.6 ± 2.5 and 5.9 ± 1.9 µWm−3 for gneisses and granites, respectively. By contrast, the heat production is low in the Kohistan–Ladakh batholith, ranging from 0.1 to 3.1 µWm−3, with the highest mean of 2.0 ± 0.5 µWm−3 in granites. The Karakoram batholith shows a large variation in heat production, with values ranging from 0.4 to 20.3 µWm−3 and the highest mean of 8.4 ± 8.3 µWm−3 in granites. The in-situ radiogenic heat production values vary in different ranges and represent considerably higher values than those previously used for the thermal modeling of Himalaya. A conductive 1D thermal model suggests 93–108 °C hotter geotherms, respectively, at 10 and 20 km depths due to the thick heat-producing layer in the upper crust, resulting in a surface heat flow of 103 mWm−2. The present study provides first-order radiogenic heat production constraints for developing a thermal model for geothermal assessment.

Writing as a productive skill is extremely challenging for EFL students. To promote their writing effectiveness, students' intrinsic motivation must be enhanced by allowing them to self-assign writing topics or write about topics of interest. Therefore, this study describes how EFL students become motivated by self-assigning their writing topics and identifies students' attitudes and writing skills in topic-based interest in the EFL writing context. A descriptive–diagnostic method was applied to achieve the study objectives. A sample of 200 EFL students responded to a closed-item questionnaire on intrinsic motivation based on topic-based interest in writing. In addition, 20 students participated in semi-structured interviews on their attitudes toward topic-based interest. The study sample showed a high level of intrinsic motivation based on their self-assignment of writing topics. Furthermore, female students showed higher intrinsic motivation if they could self-assign their writing topics than male students. In addition, students with higher GPAs exhibited higher intrinsic motivation. Moreover, the interviews revealed that intrinsically motivated students most enhanced their writing skills in ideas, vocabulary, and choice of words. The researchers suggest that students' self-assignment of writing topics be considered in teaching writing as it contributes to improving intrinsic motivation.

Hybrid hydrokinetic turbine (HKT) performance can be maximized with the right design and flow characteristics, but they can only be determined through a methodical process. Specifically, a computational study of modified hybrid HKT has been conducted, considering the design factors (attachment angle; radius ratio) as well as the water flow speed. The computational analysis is performed on the different configurations of hybrid HKT under different flow parameters. The computational findings showed that these factors have an effect on the overall performance characteristics of hybrid cross-flow HKT. The hybrid HKT model performs optimally at a combination of parameters with attachment angle = 60°, v = 0 .5 m/s, radius ratio = 0.4, and TSR value = 0.9. It was also determined that compared to the models with a radius ratio of 0.2, 0.6, and 0.8, this hybrid HKT model is 40 %, 1.46 %, and 20.49 % more effective. The chaotic behaviour of flow across the rotor has also been visualized.

The current research describes the use of e-mail reply suggestions from a socio-cultural perspective of some language-related variables. It also correlates how users perceive the use of e-mail reply suggestions to some variables: job, specialization, age, and gender. In this descriptive-inferential survey design, a self-developed questionnaire was distributed online to collect the data from a convenient sample of e-mail users. The analysis shows the study sample perceived medially the use of e-mail reply suggestions. There are statistically significant differences in the respondents’ means about using e-mail reply suggestions according to the variable of job for education, specialization for humanities, and gender for females. Also, ages of less than 30 and above 50 years are of significance in using e-mail reply suggestions. The study reveals a weak inverse correlation, however, statistical between using e-mail reply suggestions and the language of those suggestions. In addition, a statistically significant positive direct correlation is found between usability and culture and society of e-mail reply suggestions. In light of the findings, the study recommends the better implementation of artificial intelligence-mediated communication in e-mail reply suggestions in association with some sociolinguistic factors. Also, future related studies are suggested.

Safety training is an effective method to reduce safety issues. Immersive virtual reality (IVR) for safety training has gained attention in high-risk industries, but the trade-off between realism and abstraction in IVR-based training is not fully understood. This study investigated the impact of scenario and interaction fidelity on IVR-based forklift safety training, focusing on presence and usability. Scenario fidelity varied the Level of Development (LOD) in IVR model (high LOD vs. low LOD), while interaction fidelity varied the control interface (steering wheel and pedals vs. keyboard). A 2-by-2 experiment with 120 participants examined high/low scenario and interaction fidelity. Results showed scenario fidelity enhanced presence and usability significantly, while interaction fidelity had no effect. The realism of training scenarios is more influential for presence and immersion than control interface realism. These findings aim to balance IVR simulation fidelity and learning outcomes and help guide the development of cost-efficient IVR-based safety training.

Abstract Polypropylene (PP) has raised severe environmental issues concerning its non-degradability, with a current recycling rate of only 1%. This current study utilises Aspergillus terreus ATCC 20542 and Engyodontium album BRIP 61534a to break down PP while focusing on pre-treatment. Polypropylene granule (GPP), film (FPP) and metallised film (MFPP) are pre-treated by either UV, heat, or Fenton’s reagent. UV and heat-treated MFPP by A. terreus exhibits notable weight loss percentage (25.29% and 22.13%, respectively). Biomass production, reduction rate, Fourier transform infrared (FTIR), and scanning electron microscopy (SEM) analyses further validate the degradation rate. A. terreus incubated with UV-treated MFPP produced a relatively high biomass yield of 1.07 mg/ml. Reduction in carbonyl index and surface morphological changes reveal consistent biodeterioration evidence. This investigation demonstrates that A. terreus and E. album can grow on, change, and utilise PP as a carbon source with pre-treatments’ aid, promoting the biological pathways for plastic waste treatment.

Abstract Background It is known that ruminal acidosis can induce harmal population shifts in some ruminal bacteria profiles. However, there is little information related to alterations in faecal and ruminal bacterial communities and relevant serum lipopolysaccharide (LPS) in sheep with subacute ruminal acidosis (SARA). Objectives This study aimed to investigate alterations in the defined faecal and ruminal bacteria profiles and serum LPS and blood lactate concentrations in lambs with empirically induced SARA. Methods Fifteen lambs were served and undergone to induce SARA during a 7‐day period. Faecal and ruminal samples were taken to measure the pH and to perform the bacteriological works at 0 (just before induction), 8, 9, and 10 days of the challenge. Blood samples were collected to determine the serum LPS and lactate levels. The rumen and faecal samples were cultured to specify colony‐forming units (CFU) for Escherichia coli, Streptococcus Group D (SGD), and lactic acid bacteria (LAB). Results Serum LPS value had no significant increase in the affected lambs with SARA. Significant increasing trends were observed in faecal E. coli and LAB populations (p < 0.01). Rumen bacteriology revealed a rising trend for LAB and a falling trend for SGD populations (p < 0.01). Conclusion : Unlike cattle, LPS appears to be of minor importance in the pathogenesis of SARA in sheep. The increased ruminal and faecal LAB (4.00 × 107 CFU/ml or g) are proposed as valuable biomarkers for improving nutritional strategy and screening SARA in lambs.

The electron distribution function for gallium arsenide GaAs was calculated by using the Boltzmann transition equation in the central valley , for a range of low fields relative to the threshold field (E0 = 5.95Kv/cm) (0.3-1)E0. To obtain the distribution function, the Boltzmann transport equation was solved using a mechanism that combines the analytical and numerical methods. Analytical method involving extension of the Legendre polynomial was used and the effect of polar optical scattering was introduced as the dominant scattering mechanism in this research, as well as the effect of an asymmetric energy band structure with spherical energy surfaces in the central valley. After obtaining a partial differential equation of the second order, it is solved numerically after separation process for the variables using the direct matrix method in energy space by building a mathematical program using MATLAB. In this study, a system with dimensions of 360 × 360 was built, and the rate of change in energy was taken as 0.001.The computational system was tested by applying low electric fields, and the distribution function that was obtained had a Maxwellian distribution at very low fields, and it shifted from the Maxwellian distribution at higher fields close to the threshold field, and the results obtained were agree with previous results. While this system did not give accurate results at the high-electric fields.

Predicting the operating temperature of lithium-ion battery during different cycles is important when it comes to the safety and efficiency of electric vehicles. In this regard, it is vital to adopt a suitable modeling approach to analyze the thermal performance of a battery. In this paper, the temperature of lithium-ion NMC pouch battery has been investigated. A new formulation of lumped model based on the thermal resistance network is proposed. Unlike previous models that treated the battery as a single entity, the proposed model introduces a more detailed analysis by incorporating thermal interactions between individual cells and tabs within a single cell scenario, while also considering interactions between cells and insulators or gaps, located between the cells, within the module case. This enhancement allows for the precise prediction of temperature variations across different cells implemented within the battery module. In order to evaluate the accuracy of the prediction, a three-dimensional finite element model was adopted as a reference. The study was performed first on a single cell, then on modules composed of several cells connected in series, during different operating conditions. A comprehensive comparison between both models was conducted. The analysis focused on two main aspects, the accuracy of temperature predictions and the computational time required. Notably, the developed lumped model showed a significant capability to estimate cell temperatures within the modules. The thermal results revealed close agreement with the values predicted by the finite element model, while needing significantly lower computational time. For instance, while the finite element model took almost 21 h to predict the battery temperature during consecutive charge/discharge cycles of a 10-cell module, the developed lumped model predicted the temperature within seconds, with a maximum difference of 0.42 °C.

BackgroundMobile app development within mental health is often time- and resource-consuming, challenging the development of mobile apps for psychiatry. There is a continuum of software development methods ranging from linear (waterfall model) to continuous adaption (Scrum). Rapid application development (RAD) is a model that so far has not been applied to psychiatric settings and may have some advantages over other models. ObjectiveThis study aims to explore the utility of the RAD model in developing a mobile app for patients with borderline personality disorder (BPD) in a psychiatric outpatient setting. MethodsThe 4 phases of the RAD model: (1) requirements planning, (2) user design, (3) construction, and (4) cutover, were applied to develop a mobile app within psychiatric outpatient services for patients diagnosed with BPD. ResultsFor the requirements planning phase, a short time frame was selected to minimize the time between product conceptualization and access within a clinical setting. Evidenced-based interactive content already developed was provided by current staff to enhance usability and trustworthiness. For the user design phase, activity with video themes and a discrete number of functions were used to improve the app functionality and graphical user interface. For the construction phase, close collaboration between clinicians, researchers, and software developers yielded a fully functional, in-house–developed app ready to be tested in clinical practice. For the cutover phase, the mobile app was tested successfully with a small number (n=5) of patients with a BPD. ConclusionsThe RAD model could be meaningfully applied in a psychiatric setting to develop an app for BPD within a relatively short time period from conceptualization to implementation in the clinic. Short time frames and identifying a limited number of stakeholders with relevant skills in-house facilitated the use of this model. Despite some limitations, RAD could be a useful model in the development of apps for clinical populations to enable development and access to evidence-based technology.

Many risk factors have been listed that predispose to the occurrence of high blood pressure (BP). Although high body mass index (BMI) is a recognized risk factor for hypertension, the cutoff value for the high BMI was not taken into consideration as a predictor risk. There is no clear data on the occurrence of hypertension in Iraq in the highly educated population. Moreover, studies on hypertension in Iraq have been limited to a few studies. To assess and study the prevalence of BP in the academic population of Babylon city, a prospective study of 100 people was conducted. In the course of 3 months, during their work at the university in the morning, the questionnaire was filled out along with the body weight measurement. The receiver operating characteristic curve was used to measure the maximum area under the curve for the BMI score. Outcomes demonstrated that despite the high level of education, the prevalence of hypertension remains unacceptable. Awareness raising about the risk factors should be addressed through ongoing health education in health sectors and media. BMI of more than 25 could be considered a predictable risk value.

Robotic surgical techniques aimed to improve patient outcomes and satisfy patient outcomes while reducing surgical morbidity and mortality. One of the most performed surgeries, robotic assisted laparoscopic radical prostatectomy (RALRP), is characterized by many factors such as steep Trendelenburg position, and challenging access to the patient. We planned to evaluate anesthesia management and postoperative patient outcomes in RALRP. Patients planned for RALRP between January 2017 and June 2021 were included. Demographic data, additional diseases and Charlson Comorbidity Index (CCI) of the patients were recorded. The methods used in anesthesia maintenance, muscle relaxant and sugammadex dose, postoperative pain treatment protocol, duration of anesthesia and surgery, length of stay (LOS) in ICU or hospital, early postoperative complications and Clavien Dindo Classification (CDC) were evaluated by examining the follow-up forms in the intraoperative and postoperative period. Two hundred and sixteen patients underwent robotic assisted laparoscopic surgery between January 2017 and June 2021 and, 141 of them (65.3%) had RALRP. The mean age of the patients was 62.38±6.94, the body mass index was 27.60±3.94, and the mean CCI was 4.08±0.93. Total intravenous anesthesia (TIVA) (n=108, 76.6%) was mostly used for anesthesia maintenance. The median time spent during anesthesia was 278.5±63.6 minutes. The median time for surgery was 239.5±65.9 minutes. According to the CDC, grade-I was 5.7%, grade-II was 2.1%, grade-IVa 7.8%. The most common complication was acute kidney injury (11, 7.8%), followed by atelectasis (4, 2.8%). 98.6% of all patients were sent to the ward from PACU, except two. The mean LOS in hospital was 4.57±2.34 days. Robotic assisted laparoscopic radical prostatectomy is most performed surgery among all robotic surgeries. We think that, patient optimization and communication between surgeon and anesthesiologist is crucial to avoid the negative effects of steep Trendelenburg position and pneumoperitoneum in terms of improving outcome. [Med-Science 2022; 11(4.000): 1482-6]

This paper implemented an HEC-RAS-based steady two-dimensional hydrodynamic model to evaluate the hydraulic characteristics and Sediment Transport Capacity (STC) of the Makhool-Samarra Reach of the Tigris River, where this part is not already investigated. This model was prepared with the aid of topographical surveys, hydraulic measurements, and laboratory tests, as well as recorded data. The main findings show that the flow velocities within most of the studied reach are considered high compared to the local and worldwide flow velocity ranges in natural rivers. Also, the Toffaleti sediment transport function with the Van Rijn fall velocity and the effective depth-to-width computation methods are the most compatible and suitable methods for computing the Sediment Transport Potential (STP) in the ‎studied reach. With the maximum flow, the computed STP was less than the average (5.7×106 tons/day) in 45% of the reach length, where the maximum STP is 8.7×106 tons/day. However, with the minimum flow, the STP intermittently fluctuates below the average (0.2×106 tons/day) in 48% of the reach length, where the minimum STP is 0.14×106 tons/day. Generally, these STPs are little more than the Tigris River in Mosul and much higher than that in Baghdad. Also, these STPs are considered high on a global scale, especially during high flow. Medium gravel is the larger grain gradation class that can be transported. It constitutes less than 0.00005 % of the STP. Furthermore, the STC computations clearly show that the suspended sediment is the dominant part of the STC and the bed material constitutes less than 0.002% of the STC of the total load. However, most of the STC ‎concerns the clay and very fine silt.

BackgroundTelemedicine has played a vital role in providing psychiatric treatment to patients during the rapid transition of services during the COVID-19 pandemic. Furthermore, the use of telemedicine is expected to expand within the psychiatric field. The efficacy of telemedicine is well described in scientific literature. However, there is a need for a comprehensive quantitative review that analyzes and considers the different clinical outcomes and psychiatric diagnoses. ObjectiveThis paper aimed to assess whether individual psychiatric outpatient treatment for posttraumatic stress disorder, mood disorders, and anxiety disorders in adults using telemedicine is equivalent to in-person treatment. MethodsA systematic search of randomized controlled trials was conducted using recognized databases for this review. Overall, 4 outcomes were assessed: treatment efficacy, levels of patient satisfaction, working alliance, and attrition rate. The inverse-variance method was used to summarize the effect size for each outcome. ResultsA total of 7414 records were identified, and 20 trials were included in the systematic review and meta-analysis. The trials included posttraumatic stress disorder (9 trials), depressive disorder (6 trials), a mix of different disorders (4 trials), and general anxiety disorder (1 trial). Overall, the analyses yielded evidence that telemedicine is comparable with in-person treatment regarding treatment efficacy (standardized mean difference −0.01, 95% CI −0.12 to 0.09; P=.84; I2=19%, 17 trials, n=1814), patient satisfaction mean difference (−0.66, 95% CI −1.60 to 0.28; P=.17; I2=44%, 6 trials, n=591), and attrition rates (risk ratio 1.07, 95% CI 0.94-1.21; P=.32; I2=0%, 20 trials, n=2804). The results also indicated that the working alliance between telemedicine and in-person modalities was comparable, but the heterogeneity was substantial to considerable (mean difference 0.95, 95% CI −0.47 to 2.38; P=.19; I2=75%, 6 trials, n=539). ConclusionsThis meta-analysis provided new knowledge on individual telemedicine interventions that were considered equivalent to in-person treatment regarding efficacy, patient satisfaction, working alliance, and attrition rates across diagnoses. The certainty of the evidence regarding efficacy was rated as moderate. Furthermore, high-quality randomized controlled trials are needed to strengthen the evidence base for treatment provided via telemedicine in psychiatry, particularly for personality disorders and a range of anxiety disorders where there is a lack of studies. Individual patient data meta-analysis is suggested for future studies to personalize telemedicine. Trial RegistrationPROSPERO International Prospective Register of Systematic Reviews CRD42021256357; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=256357

Abstract Background Coronavirus disease 2019 (COVID-19) is accompanied by activated immune-inflammatory pathways and oxidative stress, which both induce indoleamine-2,3-dioxygenase (IDO), a key enzyme of the tryptophan (TRP) catabolite (TRYCAT) pathway. The aim of this study was to systematically review and meta-analyze the status of the TRYCAT pathway, including the levels of TRP and kynurenine (KYN) and the activity of IDO, as measured by the ratio of KYN/TRP. Methods This systematic review searched PubMed, Google Scholar, and Web of Sciences and included 14 articles that compared TRP and tryptophan catabolites (TRYCATs) in COVID-19 patients versus non-COVID-19 controls, as well as severe/critical versus mild/moderate COVID-19. The analysis was done on a total of 1269 people, including 794 COVID-19 patients and 475 controls. Results The results show a significant (p

The fruits of wild fig, native to Soon valley of Pakistan, were appraised for phenolic compounds and high-value nutrients. These fruits were shade-dried and extracted with different solvents of varying polarity to recover a wide range of antioxidant components, where hydroxyethanol exhibited highest extraction yield of antioxidant compounds. Among others, hydroxyethanol-derived crude concentration extracts (CCEs) and phenolic rich fractions (PRFs) showed greater amount of total phenolic, flavonoids and superior biological properties. The fruits of tested fruits were found to possess potassium (11.34 g/kg) and calcium (4.19 g/kg) as major elements, glucose (5.63g/100g DW) as dominant natural sugar and acetic acid (2.40 mg/100 g of dry matter) as principal organic acid. There was a considerable (p

تعد نهاية الحرب العالمية الثانية ( 1939 ــــ 1945 ) نقطة تحول بارزة في العلاقات الدولية , فقد ظهرت قوى جديدة اصبح لها دوراً كبيراً في مجال السياسة الدولية , هما الولايات المتحدة الامريكية زعيمة الدول الغربية , والاتحاد السوفيتي زعيم الدول الشرقية , اذ شهدت الخمسينيات سلسلة من محاولات الدول الغربية عن فرض المشاريع والاحلاف الغربية المشتركة لتطويق الاتحاد السوفيتي للحد من نشاطه ومنع توسيع نفوذه في منطقة الشرق الاوسط ولاسيما المنطقة العربية , وذلك للحفاظ على مصالحها الاقتصادية بالمنطقة , وحماية اسرائيل من الاعتداءات العربية ومن هذه المشاريع والاحلاف , التصريح الثلاثي ايار 1950 , ومشروع قيادة الشرق الاوسط 1951 , وحلف بغداد 1955 اذ رفضت سوريا هذه المشاريع واعتبرتها تدخلا في الشؤون الداخلية لدول المنطقة العربية ولاسيما سوريا .

Abstract Students need more independent roles to evaluate their learning performance, especially in the absence of teachers’ feedback due to some constraints such as technology and poor experience. This study investigates the potential of online self-evaluation on students’ writing skills in English as a foreign language (EFL). It examines the preparatory year (PY) level one students’ most improved EFL writing areas and perceptions when they use online self-evaluation in writing. In this quasi-experiment, two groups of PY EFL writing program students (N = 60) participated in the study for the first semester 2020–2021. A mixed-method design was applied: Self-monitoring checklists, self-evaluation questionnaires, achievement tests, and students’ portfolios. Findings revealed that most of the learners’ mistakes were in punctuation marks, capitalization, informal language, and subject-verb agreement. It was also perceived that learners were doing fine about where and how they should be. The study proved that the students’ self-evaluation and performance in writing correlated significantly; however, the effect size was low. Based on the research findings, it is recommended that training programs on strategy are to be boosted, especially in institutions where learners receive less feedback.

The study aims to summarize and assess the various interpretations of rising China. The rise of China after the Cold War is the most debated topic in international relations and its multiple implications for global politics. Due to the rapid growth of China, it has become the world's second-largest–economy. The United States, as an established hegemonic power, has concerns about the economic and as well as military advancement of rising China. This paper examines both realist and liberal perspectives regarding the rise of China. Different scholars have conflicting views about China's hegemony, or whether China may challenge the global liberal order. According to the realist perspective, China's economic growth leads to the development of military capabilities on one side. On the other side, it will become a regional hegemon and a global hegemonic power. The liberal perspective mostly focuses on the economic engagement of China with its neighboring countries as well as with the world. The article develops the concept of the grand strategy of China by engaging world nations economically through the one Belt and One Road Initiative, which can lead to enhancing its sphere of influence. China’s rise could also increase the tensions with the United States, which may cause tremendous effects on global politics. China is achieving more international responsibilities and claiming its role according to its strength and capacity.

In this paper, we aim to evaluate the efficacy of antidiabetic cardioprotective molecules such as Sodium-Glucose Cotransporter-2 Inhibitors (SGLT-2i) and Glucagon-like Peptide 1 Receptor Agonists (GLP-1 RAs) when used with other glucose-lowering drugs, lipid-lowering, and blood pressure (BP)-lowering drugs in a real-life setting. A retrospective, observational study on 477 patients admitted consecutively in 2019 to the outpatient clinic of a tertiary care unit for Diabetes Mellitus was conducted. Body mass index (BMI), blood pressure (BP) (both systolic and diastolic), and metabolic parameters, as well as A1c hemoglobin, fasting glycaemia and lipid profile, including total cholesterol (C), HDL-C, LDL-C and triglycerides), were evaluated at baseline and two follow-up visits were scheduled (6 months and 12 months) in order to assess the antidiabetic medication efficacy. Both SGLT-2i and GLP-1 RAs were efficient in terms of weight control reflected by BMI; metabolic control suggested by fasting glycaemia and A1c; and the diastolic component of BP control when comparing the data from the 6 and 12-month visits to the baseline, and when comparing the 12-month visit to the 6-month visit. Moreover, when comparing SGLT-2i and GLP-1 RAs with metformin, there are efficacy data for SGLT-2i at baseline in terms of BMI, fasting glycaemia, and HbA1c. In this retrospective study, both classes of cardioprotective molecules, when used in conjunction with other glucose-lowering, antihypertensive, and lipid-lowering medications, appeared to be efficient in a real-life setting for the management of T2DM.

This research project bridges the gap between Saudi Vision 2030 and labor market needs by strengthening English as a Foreign Language (EFL) students' critical thinking skills. The increasing unemployment rates may not be due to insufficient vacancies in the labor market, but graduates' lack of the general abilities deemed vital to meet the labor market needs. With employability in mind, this study reiterates that graduates should ideally be advanced specialists, critical researchers, creative initiators, and active communicators to be more competitive and contribute to the prosperity of their nation. Therefore, this research employs a quasi-experimental design (time series design) to investigate how effectively students' critical thinking skills are enriched using a video-mediated self-study program through Telegram. Studies in this respect, regarding the Saudi EFL context, are limited. Therefore, this research employed a video-mediated self-study program through Telegram on learning critical thinking skills for EFL students majoring in English or Translation. The data collection included a pre-and post-test on critical thinking skills and a semi-structured interview. The findings showed that students improved their critical thinking skills due to the training program compared to their performance before the treatment at a low level. Besides, the participants evaluated learning critical thinking skills from thinking ways, feelings, benefits, motivation, challenges and problems, and suggestions. In light of the findings, recommendations were presented.

The Mehri Language is an endangered language spoken in eastern Yemen, a sub-group of the Semitic language family, and a Southern Arabic language. The syntax of Mehri wh-questions has not been explored within minimalism; hence, there is a morpho-syntactic need to provide a modern analysis of wh-questions in order to show how the interrogative structures can be derived. This study aims to examine the syntax of the wh-question movement in Mehri's unaccusative/ergative and unergative structures and answer the following questions within Chomsky's (2000 and 2008) Phase-based Theory: (i) Does the Mehri language allow fronting of wh-phrases to [Spec-CP]? And (ii) how can wh-movement in Mehri unaccusative and (un)ergative structures be accounted for? This work presents a novel analysis of wh-question movement in unaccusative/ergative and unergative structures in Mehri; it demonstrates that the source head C triggers the movement of wh-adjunct and wh-subject phrases. In wh-adjunct extraction, two strategies are employed: overt wh-fronting and wh-in-situ; when the head Foc inherits an edge feature from C, wh-adjunct overtly undergoes movement from its original position within v*P to the left peripheries of [Spec-FocP] and subsequently to [Spec-CP]. When the lexical wh-adjunct remains within v*P, its question features covertly move to [Spec-CP], because the head Foc does not inherit an edge feature from C. In wh-subject extraction, the wh-subject overly undergoes movement to [Spec-CP] because C obligatorily inherits the edge feature to the head Top, which triggers movement of the illogical subject in unaccusative/ergative structures and the logical external specifier in unergative structures to [Spec-CP]. Moreover, Mehri obeys the Phase Impenetrability Condition of Chomsky, where wh-subject and wh-adjunct phrases must pass through certain phases until [Spec-CP].

Studies and reports indicate that some graduates struggle to find jobs, in part because they lack the key presentation skills and competencies the labor market needs. Thus, this research investigated the effectiveness of a Blackboard-mediated intervention program in strengthening English as a foreign language (EFL) students' presentation skills. The research followed a quasi-experimental (time series) design, delivering workshops on presentation skills and collecting data from the students (N = 30) using a set of instruments: a pre-and post-assessment checklist and semi-structured interviews. The results showed that the students' presentation skills improved significantly post intervention. Also, the participants reported positive attitudes concerning the intervention. Drawing on these findings, recommendations and suggestions are presented.

This study investigates the empirical impact of China-Pak business cycle synchronization, urbanization, foreign direct investment, exports, and imports on environmental degradation in Pakistan from 1975 to 2017. In doing so, we use the Hodrick-Prescott filter to obtain the trend component of GDP. Then the trend component is subtracted from the original series of GDP to capture the cyclical component of China and Pakistan. The business cycle synchronization index is used to estimate synchronization between the business cycles of both countries. Using the ARDL method, we investigate the existence of a long-run co-integration relationship between the variables of interest. The empirical findings indicate that all explanatory variables (except FDI) are found to be significant factors of environmental degradation in the model. Furthermore, both imports and urbanization have a positive and significant impact on environmental degradation in Pakistan. At the same time, China-Pak business cycle synchronization and exports are discovered to have negative and significant coefficients for environmental degradation in Pakistan. The negative and significant ECM value indicates model convergence and a short-run relationship. The findings of the study suggest that improvement in China-Pak business cycle synchronization may be a factor that promotes environmental sustainability in Pakistan. An increase in exports and a decrease in imports can significantly contribute to reducing environmental degradation in Pakistan. A favorable balance of payment can provide sufficient financial prosperity to take environmental preservation measures. Policymakers should create effective urban planning, which has the potential to improve the country’s environmental quality.

Comprehension is one of the most crucial factors contributing to acquiring a new language; therefore, teachers must facilitate language comprehensibility using the best teaching practices to help learners understand the target language. This study aimed to identify tertiary EFL teachers’ practices for teaching language comprehensibility to assist in highlighting the comprehensibility practices tertiary EFL teachers employ to ensure that students understand, interact with, and use the English language. To identify the extent that the teachers employ language comprehensibility practices in an EFL context, the descriptive-correlational approach was employed. A closed-item questionnaire was administered to a sample of 65 teachers in Najran University, Saudi Arabia in the academic year 2021–2022. The Statistical Package for Social Sciences (SPSS v. 23) was used to analyze the data. The results showed that tertiary EFL teachers taught language comprehensibility very skillfully. Also, no significant difference in teaching language comprehensibility was found concerning the gender variable. There were, however, differences in the means of the sample’s responses towards methods of teaching language comprehensibility according to years of experience, particularly for those with the most years of experience. Considering the results, the study suggested paying more attention to integrating language comprehensibility practices in EFL contexts.

IntroductionHarmful alcohol use is a significant public health problem worldwide, though the alcohol-related burden affects disproportionately certain populations and ethnic minorities, with the WHO European Region being the most heavily affected and putting an increased risk on Roma populations. This ethnic minority group is the largest and most vulnerable ethnic minority in Europe and Hungary as well.MethodsThe present study aims to describe and compare the alcohol consumption behaviors of the Hungarian general and Roma populations using the Alcohol Use Disorders Identification Test (AUDIT), which provides a comprehensive view of alcohol consumption behavior. In addition, a decomposition analysis was performed when the multivariate logistic or Poisson regression model showed significant differences between the two samples.ResultsOur findings suggest that Roma people in our study sample experience more alcohol-related harm, even when considering past problems. The decomposition analysis revealed that gender and relationship status differences act more intensely among Roma than non-Roma when considering alcohol-related harm.DiscussionEqualizing these differences would be expected to reduce the Hungarian general and Roma populations' alcohol-related harm frequency gap. Investigating alcohol-attributed harms at the ethnicity level provides important information to identify high-risk groups and, thus, to design and implement more targeted and accessible interventions for alcohol problems.

This work aims to use the digital elevation model (DEM) or 3-Dimensional surface to model and analyze the water flow in the Tigris River. The first stage of this study is based on filed data acquisition survey at 38 stations. These stations were adopted to implement the one-dimensional steady and unsteady numerical flow models. The HEC-RAS software was used to implement these models. The most important results of the steady-state model were that the maximum discharge and velocity and minimum flow area were 638.17 m3/sec, 2.12 m/sec and 301.42 m2 respectively. These values occurred at station 66+700. While, the minimum discharge and velocity and maximum flow area were 504.5 m3/sec, 0.13m/sec and 4758.13 m2 respectively. The results of unsteady state were analyzed based on the recorded discharge in the year 2018. The maximum and minimum discharge (flow velocity) were 638.12 m3/sec (2.42 m/sec) at the stations 94+666+7 and 635.57 m3/sec(0.14 m/sec) at station 00+00, respectively. The maximum and minimum Froude number were 0.52 and 0.02 at stations 94+666+7 and 04+800, respectively. These results help to identify the flow choking areas that cause defects. In addition, it can be the base for determining the critical sedimentation stations in which the bed level rises and aggravate the flow choking problem within the considered reach of the Tigris River.

The bioactive extracts recovered from Curcuma longa (stem), Mentha aquatica (stem and leaves), Emblica officinalis (fruits), Nigella sativa (seeds), and Glycyrrhiza glabra (stem) using methanol and ethanol, were appraised for antioxidant (total flavonoid contents, total phenolic contents, DPPH free radical scavenging ability, inhibition of linoleic acid peroxidation and reducing power) and antimicrobial attributes. Total phenolics (16.89 ± 0.18 - 25.06 ± 0.31g GAE/100g) and total flavonoids (1.96 ± 0.07 - 13.54 ± 0.18 CE g/100g) contents of aqueous methanol extracts of tested plant materials were significantly (p < 0.05) lower than that of aqueous ethanol extracts (13.87 ± 0.12 - 28.63 ± 0.34 g GAE/100g) and (2.20 ± 0.10 - 8.71 ± 0.24 CE /100g), respectively. The percent inhibition of linoleic acid per oxidation by crude ethanol extracts of plants was in the range of 48.72 ± 1.24 - 70.79 ± 1.57 and crude methanol extract 35.90 ± 1.28 - 61.54 ± 2.14, while the range of DPPH free radical scavenging activity of ethanol extracts was (58.36 ± 1.98 - 80.55 ± 3.07) and methanol extracts (39.55 ± 1.52 - 79.64± 2.33). The reducing power of the tested extracts obtained by ethanol (at the concentration of 10 mg/mL) ranged 1.11 ± 0.12 – 1.53 ± 0.18 while for methanol extracts 0.98 ± 0.11 – 1.39 ± 0.12. Among the attributes analyzed, total phenolics, total flavonoids, and DPPH free scavenging activity were found to be varied significantly in all the tested medicinal plants. The extracts from all plants showed good antimicrobial potential against a penal of bacteria, including E. coli, P. multocida and S. aureus, and fungi including A. niger, A. flavus, A. alternate, and G. lucidium. Overall, the tested samples were found to be a good source of natural antioxidant and antimicrobial agents and thus can be explored for potential functional food and nutra-pharmaceutical applications.

Background: Ambient air pollution is a pervasive and ubiquitous hazard, which has been linked to premature morbidity and a growing number of morbidity endpoints. Air pollution may be linked to neurodegeneration, and via this or other pathways, to neurodegenerative diseases. Emerging evidence suggests that air pollution may contribute to neurodegenerative diseases such as dementia, Parkinson’s Disease (PD), Multiple Sclerosis (MS) and Motor Neuron Diseases (MND), although this evidence remains inconsistent and very limited for MS and MND. In addition, this evidence base is rapidly emerging and would benefit from a wide and critical synthesis, including a better understanding of heterogeneity. Objectives: In this paper, we present a protocol for a systematic review and meta-analysis and specify our methods a priori. The main aim of the planned systematic review is to answer the question of whether long-term exposure (>1 year) to ambient (outdoor) air pollution (exposure, compared to lower exposure) increases the risk of adult (population) incidence of neurodegenerative diseases (outcomes) in epidemiological observational studies (study design). Another aim is to meta-analyze the associations between long-term exposure to ambient air pollutants and the risk of the selected outcomes and assess the shape of exposure–response functions. To set the stage for the proposed work, we also overview the existing epidemiological evidence in this protocol, but do not critically evaluate it, as these results will be fully presented in the planned systematic review. Search and study eligibility: We will search the electronic databases Medline (via Ovid), Embase (via Ovid), Cochrane Library, Cinahl (via Ebscohost), Global Health (via Ebscohost), PsycINFO (via Ebscohost), Scopus, Web of Science (Core Collection), from inception to October 2022. Eligible studies must contain primary research investigating the link between 1-year + exposure to any outdoor air pollutant, from any source, and dementia, PD, MS, and MND, or dementia subtypes: Alzheimer’s Disease, vascular dementia, and mixed dementia. The search strategy and eligibility criteria are pre-determined and described in full in this protocol. Study appraisal and synthesis methods: Articles will be stored and screened using Rayyan QCRI. Title and abstract screening, full text review, data extraction, risk of bias assessment and data preparation for statistical analysis will be conducted independently by two reviewers using pre-defined forms and criteria, described in this protocol. All these steps will also be piloted and the forms and/or methods adapted if issues arise. Meta-analysis and assessment of the shape of the exposure–response functions will be conducted if four independent exposure-outcomes pairs are available, and the remainder of results will be synthesized in the forms of tables and via a narrative summary. Certainty in the body of evidence will be assessed using the OHAT approach. This protocol describes the planned analysis and synthesis a priori and serves to increase transparency and impact of this systematic review and meta-analysis.

In this study, wild olive fruits were evaluated for the occurrence of phenolic antioxidant components and valuable nutrients which are distributed wildly in Soon valley of Pakistan. The shade-dried fruits of wild olive were extracted using different solvents to recover phenolic antioxidants. The highest concentration of extractable antioxidant components was recovered from tested fruits using aqueous ethanol compared to other solvents used. Crude concentrated extracts (CCEs) and phenolic rich fractions (PRFs) of tested fruits using hydroxyethanol were found to contain higher amount of total phenolic compounds and total flavonoid compounds along with superior biological attributes. According to ICP-OES analysis, potassium (17.96 g/kg) was the dominant macro element among other identified twenty-five minerals. The tested wild olive fruits juice was found to contain individual natural sugars including galactose (4.92 g/100 g dry weight), sucrose (2.75 g/100 g dry weight), glucose (0.73 g/100 g dry weight); and succinic acid (8.80 mg/100 g of dry matter) as major organic acid when analyzed on HPLC. Oleic acid (47.41 %) was the major monounsaturated fatty acid in the oil extracted from tested fruits. The concentration of phenolic antioxidants and biological activities vary significantly (p

The present study reports the phenolic antioxidants and phytonutrients profiling in the wild jujube fruits which are naturally grown in Soon valley of Pakistan. Phenolic antioxidant components were recovered from shade-dried wild jujube fruits using various extracting solvents. Among all extracting solvents tested, aqueous ethanol recovered the maximum amount of extractable antioxidant compounds from the fruits of wild jujube. Crude concentrated extracts (CCEs) and phenolic rich fractions (PRFs) recovered from wild jujube fruits using aqueous ethanol contained higher concentration of total phenolics and flavonoids along with superior biological potential. ICP-OES analysis disclosed the occurrence of twenty-five minerals, where potassium (14.80 g/kg) and calcium (1.81 g/kg) were the dominant macro elements. The tested wild fruits juice was found to contain individual natural sugars including galactose (1.27 g/100 g dry weight), glucose (1.07 g/100 g dry weight), sucrose (0.70 g/100 g dry weight) and xylose (0.04 g/100 g dry weight); and gluconic acid (2.10 mg/100 g of dry matter) as dominant organic acid when analyzed on HPLC. The concentration of phenolic antioxidants and biological activities vary significantly (p