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Background: Adolescents frequently self-report pain, according to epidemiological research. The knee is one of the sites where the pain is most common. One of the main factors contributing to the number of years people spend disabled and having substantial personal, societal, and economic burdens globally is musculoskeletal disorders. Insidious, slowly building onset that neither the adolescent nor the parent is aware of [5]. Patellofemoral Pain (PFP) is a clinical knee pain commonly affecting adolescents. In the present study, the authors aimed to estimate the frequency of knee pain in Saudi adolescents. Methods: This cross-sectional survey carried out from June to November 2022 included 676 adolescents, ages 10 to 18. The data are presented as frequencies and percentages for categorical variables. Analysis of variance (ANOVA) was used to compare means between groups, while the chi-square test was used for the comparison of categorical variables. Statistical significance was set at p < 0.05. Results: Adolescents were invited to take part in the study; 57.5% were female and 42.5% were male, and 68.8% were aged between 15 and 18. The prevalence of knee pain was considerably high among females (26%), while it was 19.2% among males. Moreover, age was a significant predictor for knee pain, and BMI was as well. We also found a significant difference between BMI classification and stiffness of the knee (p = 0.008). There is a difference between adolescents who do physical activities in leisure and difficulty bending (p = 0.03). Conclusion: Our study noted a high rate of knee pain among adolescents, so we need to raise awareness about risk factors. Adolescent knee pain can be prevented with conservative methods and some minor lifestyle/activity modifications.

Giant cell tumors of the bone (GCTB) are rare, benign, aggressive, recurrent tumors that are most often found at the ends of long bones. They account for 5% of all primary bone tumors and 20% of all benign bone tumors. The clinical features of GCTB include local swelling, pain, and limitations in joint movement. Approximately half of GCTB arise around the knee joint, affecting either the distal femur or proximal tibia. Tissue biopsy reveals an excess of multinucleated giant cells on a stromal cell background, indicating a diagnosis. Intralesional curettage is used to treat GCTB and is associated with minimal disability; however, local recurrence may occur in many patients. Resection and endoprosthetic repair or bone graft reconstruction are often used to treat GCTB near the joint. To our knowledge, there are currently no studies on this topic in the city of Jeddah, where we conducted our study. Our aim was to evaluate the outcome of surgical resection accompanied by denosumab injection compared to that of surgery alone in treating GCTB.All cases of GCTB at King Abdulaziz Medical City, Jeddah, between January 2008 and December 2018, that fulfilled the inclusion and exclusion criteria were included. All cases of GCTB in the pre-specified period were classified as surgical resection with denosumab injection or surgical resection alone. The outcomes of the two modalities were compared. Recurrence was investigated in patients belonging to both the groups.Twenty-six cases that met the inclusion criteria were included in the study and the data were analyzed. The subjects were divided into two groups: denosumab and surgery (n = 7) and surgery alone (n = 19). Patients treated with denosumab and surgery had a higher recurrence rate (57%); however, the difference was not significant (p = 0.407).Our study showed that when comparing local recurrence after curettage in patients treated with denosumab and patients who did not receive it, preoperative denosumab therapy was associated with an increased incidence of local recurrence. We recommend a systematic review that can include more studies in this field to acquire more definitive results regarding this topic.

Background Hip fracture is a major medical and surgical topic and is a significant cause of morbidity and mortality. Older women, especially those with osteoporosis, are at an increased risk for hip fractures. Multiple studies have shown the effect of osteoporosis on the refracture rate among the elderly population. Therefore, selecting a targeted population for screening and treating osteoporosis has an essential role in decreasing the hip fracture rate. This study aimed to determine the association between osteoporosis treatment and refracture rate among patients with hip fractures at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Methods Collected data included patient demographics (men: ≥55 years old; women: ≥50 years old), the used osteoporosis investigation method, osteoporosis treatment history, presence of comorbidities, and refracture as a primary outcome. The refracture rate among patients with hip fracture was calculated and used to determine the association between hip refracture and osteoporosis. Results Our study included a total of 292 patients who presented to our hospital due to hip fractures. The patients were divided into two groups, the osteoporotic and non-osteoporotic groups. These groups were then compared. There was no statistical significance between osteoporosis and hip refracture (p = 0.721), and there was no association between the treatment of osteoporosis and hip refracture (p = 0.493). Statistical difference was found between patients who had undergone dual-energy X-ray absorptiometry scan and were not treated for osteoporosis (p = 0.00). Lastly, the mortality of the refracture group was 10%, while it was 11% in the no-refracture group (p = 1.00). Conclusion Morbidity and mortality rates are higher among patients with hip fractures. Our study showed that there was no association between hip refracture rate and osteoporosis whether the patient is treated for osteoporosis or not. We recommend a systematic review that can include more studies in this field to acquire more definitive results regarding this topic.

The fifth metatarsal base avulsion fracture (i.e., Pseudo-Jones fracture) is one of the most common foot fractures. The management of pseudo-Jones fractures could be carried out surgically or conservatively. This systematic review and meta-analysis aimed to provide an update about the efficacy of orthotic removable support compared to short-leg casting for individuals with pseudo-Jones fracture.We searched Embase, Medline, and Cochrane Central register of Controlled Trials (CENTRAL) for randomized controlled trials (RCTs) that compared the clinical outcomes of orthotic removable support and short-leg cast for adult individuals with a fifth metatarsal base avulsion fracture. We used 95% as a confidence level and P0.05 as a threshold. The standardized mean difference (SMD) was used for the continuous outcomes, and the risk ratio (RR) was used for the dichotomous outcomes.A total of 6 RCTs incorporating 403 individuals out were deemed eligible. There was no significant difference between orthotic removable support and short-leg casting regarding AOFAS score (standardized mean difference (SMD)= 0.31, 95% CI -0.17 to 0.8), pain on VAS score (SMD= -0.08, 95% CI -0.39 to 0.22), VAS-FA score (SMD= 0.22, 95% CI -0.19 to 0.62) EQ-5D VAS score, and non-union rate (RR=0.37, 95% CI 0.05 to 2.74).The current meta-analysis reveals that there is no difference between orthotic removable support and short-leg casting for the conservative management of individuals sustaining pseudo-Jones fracture.

Background To evaluate the effect of screening for sepsis using an electronic sepsis alert vs. no alert in hospitalized ward patients on 90-day in-hospital mortality. Methods The SCREEN trial is designed as a stepped-wedge cluster randomized controlled trial. Hospital wards (total of 45 wards, constituting clusters in this design) are randomized to have active alert vs. masked alert, 5 wards at a time, with each 5 wards constituting a sequence. The study consists of ten 2-month periods with a phased introduction of the intervention. In the first period, all wards have a masked alert for 2 months. Afterwards the intervention (alert system) is implemented in a new sequence every 2-month period until the intervention is implemented in all sequences. The intervention includes the implementation of an electronic alert system developed in the hospital electronic medical records based on the quick sequential organ failure assessment (qSOFA). The alert system sends notifications of “possible sepsis alert” to the bedside nurse, charge nurse, and primary medical team and requires an acknowledgment in the health information system from the bedside nurse and physician. The calculated sample size is 65,250. The primary endpoint is in-hospital mortality by 90 days. Discussion The trial started on October 1, 2019, and is expected to complete patient follow-up by the end of October 2021. Trial registration ClinicalTrials.gov NCT04078594. Registered on September 6, 2019

Background: Oteoid osteoma is a benign bone tumor that affects mainly children and adolescents. Most patients complain of pain as the main symptom, which is usually managed by analgesia. Less commonly, the lesion can lead to bone deformity or restricted mobility. Ultimate treatment of this disease is to remove the lesion surgically, or by the recently adopted, less invasive, per-cutaneous radiofrequency thermo-ablation. Objective of the study: To evaluate the outcome of patients diagnosed with osteoid osteoma treated with either surgical resection or per-cutaneous radiofrequency thermo-ablation (PRT). Methods: Our data were collected during the period from January 2000 to December 2016. A total number of 28 patients who underwent either surgical resection or PRT therapy were included. We evaluated the presence of residuals after treatment, symptomatic relief, recurrence rate, and length of stay at hospital following treatment. Results: Mean age of diagnosis in our patients was 14.7 years (±7.63), and 13 patients (46%) underwent surgical treatment, and 15 had PRT therapy (54%). The presence of post-therapy residuals, symptoms relief, and recurrence rate were not significantly different between the two treatment groups, while median length of stay post-op (surgical = 4 days, PRT = 1 day) was significantly different and favored PRT treatment group (p-value=< 0.001). Conclusion: PRT therapy was shown to be less invasive, safer, and significantly reduced the lengths of stay, which could be a determinant factor in fast recovery to patients and a cost-effective option.

Objectives: The corona virus disease 2019 (COVID-19) pandemic has had a global effect and the Saudi Government has reacted aggressively to control the disease. Cancer patients are more susceptible to disease due to reduced immunity and are at higher risk of developing severe disease. In this article, we discuss the recommendations on slowing down the spread and easing the severity of COVID-19 in such patients. Methods: We have outlined guidelines and recommendations to be followed by orthopedic oncology centers in Saudi Arabia. These have been distributed to the Saudi Orthopedic Association-Oncology Chapter (SOA-OC) members for suggestions and recommendations. Results: A review of the literature was performed by searching for articles discussing COVID-19 measures related to cancer patients or patients undergoing surgical interventions during the pandemic. The authors discussed the recommendations and algorithmic pathways that were created to be implemented in orthopedic oncology centers around the country. Recommendations were reviewed by the SOA-OC members, who reached an agreement on application and publication. These recommendations focused on orthopedic cancer patient protection during clinical visits, inpatient, and surgical interventions. In addition, we discussed the recommendations for staff protection, including minimizing patient contact and continuing medical education during the pandemic. Conclusion: The reported algorithms and recommendations could help orthopedic oncology centers protect both their patients and staff from COVID-19 infection. These measures are highly recommended for continuing the treatment offered to orthopedic oncology patients, regardless of their infection status with COVID-19 during the pandemic.

Introduction Social media continues to grow in size, and popularity, The prevalence of social networking continues to develop and will likely play an increasing role in all aspects of society and business, including in healthcare services. This rapid growth has directly influenced healthcare professionals in the clinical setting. Aim To assess the perceptions and usage of SM (SM) by OSs (OS) in Jeddah, Saudi Arabia, and its impact on their profession, and to evaluate their level of awareness of the potential risks on their practice. Methods Quantitative: A cross-sectional survey was distributed to practicing OSs in 15 healthcare centers in Jeddah, Saudi Arabia (μ=323) using convenience sampling. Data was analyzed using SPSS. Qualitative: Eight OSs were recruited by purposive and snowball sampling and interviewed using a semi-structured approach. Data was analyzed using thematic content analysis. Results The Quantitative survey revealed that 165 OSs participated (RR=51%). OSs who use SM partly or entirely for professional purposes represent 53.7% (n=87). The remaining OSs were excluded. Virtually 90% were 40 years old or younger. Residents were less likely to reply to medical questions on SM (p=0.035). It was found that 74.7% of OSs use SM daily. The most commonly used platform was Twitter (75.9%), with Instagram and Snapchat being significantly more used by younger OSs (p= 0.013 and 0.003, respectively). The results of the Qualitative interviews revealed four themes: Guidelines, Ethics and Professionalism; Usage and Perceptions; Doctor-Patient Relationship; Quality of Online Content. Conclusion OSs' perceptions and usage were generally cautious. The major concerns were patient confidentiality, along with ethical and legal consequences. The need to contribute to quality online content was evident. Lack of formal guidelines was a continuous theme. The development of national guidelines on SM use in the orthopaedic profession is recommended.

This study compared the surgical, oncological, and functional outcomes of patients undergoing limb-salvage surgery for extremity soft tissue sarcoma with vascular resection and reconstruction with the outcomes of those undergoing limb-salvage without vascular reconstruction.Nineteen patients were identified from a prospective soft-tissue sarcoma database who underwent vascular resection and reconstruction as part of their limb-salvage surgery and who were followed up for at least 1 year or until death. Each of these 19 patients was case-matched to 2 additional patients on the basis of tumor location, size, and depth; patient age; and timing of radiation. To compare functional outcome, a subset of patients was case-matched with additional criteria including wound-complication status, motor nerve sacrifice, similar preoperative function as determined by the Toronto Extremity Salvage Score, and no metastases at diagnosis or the 1-year follow-up.Patients in the vascular reconstruction group were more likely to require a muscle transfer (53% vs. 18%; P = .008), experience a wound complication (68% vs. 32%; P = .03), experience deep venous thrombosis (26% vs. 0; P = .003), experience significant limb edema (87% vs. 20%; P = .001), and ultimately require an amputation (16% vs. 3%; P = .07). Patients who underwent vascular reconstruction had only slightly lower Toronto Extremity Salvage Score scores 1 year after surgery (78.5 vs. 84.2; P = .35). There were no significant differences in local or systemic tumor relapse between the two groups.Vascular reconstruction is a feasible option in limb-salvage surgery for soft tissue sarcoma but is associated with an increased risk for postoperative complications, including amputation. Although function is not significantly worse after vascular reconstruction, the results are less predictable.