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1. Among substance-abusing traffic offenders, poor sleep and poor general health predict lower driving skills but not slower reaction times

Author

Abdoli N, Sadeghi Bahmani D, Farnia V, Alikhani M, Golshani S, Holsboer-Trachsler E, and Brand S

Subjects
driving, sleep, aggression, general health, reaction time, Psychology, BF1-990, Industrial psychology, HF5548.7-5548.85
Abstract

Nasrin Abdoli,1 Dena Sadeghi Bahmani,1–4 Vahid Farnia,1 Mostafa Alikhani,1 Sanobar Golshani,1 Edith Holsboer-Trachsler,2 Serge Brand1–5 1Substance Abuse Prevention Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Center for Affective, Stress and Sleep Disorders, Psychiatric Clinics, University of Basel, Basel, Switzerland; 3Kermanshah University of Medical Sciences, Sleep Disorders Research Center, Kermanshah, Iran; 4Isfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran; 5Division of Sport Science, and Psychosocial Health, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland Background: Traffic accidents are a significant health issue in Iran. Explanations for such accidents have included single consideration of the role of poor sleep and negative psychological trait and state variables. In this study, we examined whether and to what extent sleep, general health, and aggression can concomitantly predict driving behavior. Methods: A total of 360 male traffic offenders (driving under substance use; mean age: 31 years) participated in this study. They completed the questionnaires covering sociodemographic, sleep-related, and behavior-related variables. In addition, their visual and acoustic reaction times were objectively tested. Results: Poor sleep, poor general health, and higher aggression scores were associated with self-rated poor driving behavior. Poor sleep was directly associated with poor driving behavior and indirectly via poor general health and aggression. In contrast, visual and acoustic reaction times were unrelated to sleep, general health, aggression, or self-rated driving behavior. Conclusion: To our knowledge, this is the first study in Iran to assess concomitantly poor sleep, poor general health, and higher aggression scores as independent predictors of poor driving behavior among a larger sample of substance-abusing traffic offenders. Furthermore, visual and acoustic reaction times were unrelated to sleep, general health, aggression, and driving behavior. Finally, importantly, poor sleep predicted both directly and indirectly poor driving behavior. Keywords: driving behavior, sleep, aggression, general health, reaction time

Published
2018

2. Radiosurgery for skull base meningiomas: a study on 230 cases in Iranian Gamma Knife Center

Author

Ali Bitara M, Azar M, Miri SM, Sheikhrezai A, Alikhani M, Allahverdi M, Sharif Tabrizi A, and Tayebi Meybodi A

Subjects
Skull base meningioma, gamma knife, radiosurgery, Medicine (General), R5-920
Abstract

"n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Meningiomas are among the most common tumors of the brain. Skull base meningiomas comprise s major part of brain meningiomas. They are difficult to treat because of proximity to major vital neuro-vascular structures which makes their surgical resection hazardous and fraught with a high rate of complications. Radiosurgery is considered as an alternative efficient way to treat them, which targets the tumor and its supplying vasculature. The standard treatment consists of tumor eradication and its supplying vessels through homogeneous dose of 201 rays of cobalt 60 source."n"nMethods: In a case-series study, we report 230 meningiomas referred to Iraninan Gamma Knife Center, treated by radiosurgery with type C Gamma Knife. Radio-surgery was performed at a mean dose of 15 Gy and 50% isodose."n"nResults: Two hundred and thirty of all meningioma cases refered to our institute were skull base lesions. Eighty (35%) were new case and the rest were previously treated microsurgically one or more times. None of the patients died after treatment and the most common post-operative complications were headache (30 patients) and peri-tumoral edema (12 patients)."n"nConclusion: Tumoral control is defined as reduced tumor volume or as no change in tumor volume. Tumor control was achieved in 218 (95%) patients. In those who were not treated microsurgically, clinical improvement was more pronounced. Thus when suitable (favorable tumor size and absence of progressive mass effect signs) the patients could be primarily treated with Gamma knife. Other patients could be managed complementarily with radiosurgery after they are treated surgically.

Published
2010

3. Some applications of uniformly $ p $-convergent sets

Author

Alikhani, M.

Subjects
Mathematics - Functional Analysis, Primary:46B25, Secondary:46E50, 46g05
Abstract

In this paper, we introduce a new class of subsets of bounded linear operators between Banach spaces which is p-version of the uniformly completely continuous sets. Then, we study the relationship between these sets with the equicompact sets. Moreover, we introduce the concept of weakly p-sequentially continuous differentiable mappings and obtain some characterizations of these mappings. Finally, we give a factorization result for differentiable mappings through p-convergent operators., Comment: arXiv admin note: text overlap with arXiv:1912.12454, arXiv:2002.01163

Published
2020

4. Sequentially Right-like properties on Banach spaces

Author

Alikhani, M.

Subjects
Mathematics - Functional Analysis, 46B20, 46B25, 46B28
Abstract

In this paper, we first study the concept of $ p $-sequentially Right property, which is the $ p$-version of the sequentially Right property. Also, we introduce a new class of subsets of Banach spaces which is called $ p$-Right$ ^{\ast} $ set and obtain the relationship between p-Right subsets and p-Right$ ^{\ast} $ subsets of dual spaces. Furthermore, for $ 1\leq p

Published
2019

5. A study of reciprocal Dunford-Pettis-like properties on Banach spaces

Author

Alikhani, M.

Subjects
Mathematics - Functional Analysis
Abstract

In this article, we study the relationship between \(p\)-\((V)\) subsets and p-\(V^*\) subsets of dual spaces. We investigate the Banach space X with the property that adjoint every \(p\)-convergent operator \(T: X \rightarrow Y\) is weakly \(q\)-compact, for every Banach space \(Y\). Moreover, we define the notion of \(q\)-reciprocal Dunford-Pettis\(\^*\)property of order \(p\) on Banach spaces and obtain a characterization of Banach spaces with this property. The stability of reciprocal Dunford-Pettis property of order \(p\) for the projective tensor product is given.

Published
2019

6. A study on Dunford-Pettis completely continuous like operators

Author

Alikhani, M.

Subjects
Mathematics - Functional Analysis, 46B20, 46B25, 46B28
Abstract

In this article, the class of all Dunford-Pettis $ p $-convergent operators and $ p $-Dunford-Pettis relatively compact property on Banach spaces are investigated. Moreover, we give some conditions on Banach spaces $ X $ and $ Y $ such that the class of bounded linear operators from $ X$ to $ Y $ and some its subspaces have the $ p $-Dunford-Pettis relatively compact property. In addition, if $ \Omega $ is a compact Hausdorff space, then we prove that dominated operators from the space of all continuous functions from $ K $ to Banach space $ X $ (in short $ C(\Omega,X) $) taking values in a Banach space with the $ p $-$ (DPrcP) $ are $ p $-convergent when $ X $ has the Dunford-Pettis property of order $ p.$\ Furthermore, we show that if $ T:C(\Omega,X)\rightarrow Y $ is a strongly bounded operator with representing measure $ m:\Sigma\rightarrow L(X,Y) $ and $ \hat{T}:B(\Omega,X)\rightarrow Y $ is its extension, then $ T$ is Dunford-Pettis $ p $-convergent if and only if $ \hat{T}$ is Dunford-Pettis $ p $-convergent., Comment: arXiv admin note: substantial text overlap with arXiv:1810.05638

Published
2019

8. On pseudo weakly compact operators of order $ P$

Author

Alikhani, M.

Subjects
Mathematics - Functional Analysis
Abstract

In this paper, we introduce the concept of a pseudo weakly compact operator of order $ p $ between Banach spaces. Also we study the notion of $ p $-Dunford-Pettis relatively compact property which is in "general" weaker than the Dunford-Pettis relatively compact property and gives some characterizations of Banach spaces which have this property. Moreover, by using the notion of $ p $-Right subsets of a dual Banach space, we study the concepts of $ p $-sequentially Right and weak $ p $-sequentially Right properties on Banach spaces. Furthermore, we obtain some suitable conditions on Banach spaces $ X$ and $ Y $ such that projective tensor and injective tensor products between $ X $ and $ Y $ have the $ p $-sequentially Right property.\ Finally, we introduce two properties for the Banach spaces, namely $ p $-sequentially Right$ ^{\ast} $ and weak $ p $-sequentially Right$ ^{\ast} $ properties and obtain some characterizations of these properties.

Published
2018

25. (‐)‐Epigallocatechin‐3‐gallate induced apoptosis by dissociation of c‐FLIP/Ku70 complex in gastric cancer cells

Author

Felordi, MS, Alikhani, M, Farzaneh, Z, Choshali, MA, Ebrahimi, M, Es, HA, Piryaei, A, Najimi, M, Vosough, M, Felordi, MS, Alikhani, M, Farzaneh, Z, Choshali, MA, Ebrahimi, M, Es, HA, Piryaei, A, Najimi, M, and Vosough, M

Abstract

Anti cancer properties of epigallocatechin 3 gallate EGCG are mediated via apoptosis induction as well as inhibition of cell proliferation and histone deacetylase Accumulation of stabilized cellular FLICE inhibitory protein c FLIP Ku70 complex in the cytoplasm inhibits apoptosis through interruption of extrinsic apoptosis pathway In this study we evaluated the anti cancer role of EGCG in gastric cancer GC cells through dissociation of c FLIP Ku70 complex MKN 45 cells were treated with EGCG or its antagonist MG149 for 24 h Apoptosis was evaluated by flow cytometry and quantitative RT PCR Protein expression of c FLIP and Ku70 was analysed using western blot and immunofluorescence Dissociation of c FLIP Ku70 complex as well as Ku70 translocation were studied by sub cellular fractionation and co immunoprecipitation EGCG induced apoptosis in MKN 45 cells with substantial up regulation of P53 and P21 down regulation of c Myc and Cyclin D1 as well as cell cycle arrest in S and G2 M check points Moreover EGCG treatment suppressed the expression of c FLIP and Ku70 decreased their interaction while increasing the Ku70 nuclear content By dissociating the c FLIP Ku70 complex EGCG could be an alternative component to the conventional HDAC inhibitors in order to induce apoptosis in GC cells Thus its combination with other cancer therapy protocols could result in a better therapeutic outcome

Published
2023

26. Optimal implementation of consumer demand response program with consideration of uncertain generation in a microgrid

Author

Alikhani, M, Moghaddam, MP, Moazzen, F, Azadi, A, Alikhani, M, Moghaddam, MP, Moazzen, F, and Azadi, A

Abstract

Power systems encounter frequent challenges related to imbalances between load and generation, prompting the exploration of Demand Side Management (DSM) techniques, notably through the adoption of Demand Response Programs (DRPs). Nevertheless, integrating DRPs into smart grids presents complexities. This research paper proposes an enhanced Weighted Fuzzy Average (WFA) K-means clustering algorithm to effectively group consumers' load patterns. Furthermore, the behaviors of DRP implementations for each consumption cluster are modeled in both linear and nonlinear fashions, utilizing the Coefficient of Participation (CoP) as the foundation for these models. To identify the most optimum DRP program, the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) method is employed, with decision indicators weighted using Shannon entropy. The proposed method is then evaluated by simulating a 33-bus Microgrid (MG) with uncertain generation, incorporating wind turbine, photovoltaic, and Battery Energy Storage System (BESS) components. The outcomes demonstrate that through the optimal application of DRPs in a microgrid, diverse objectives of consumers and utility companies can be successfully attained.

Published
2023

27. POS1172 GEOGRAPHICAL VARIABILITY OF ORGAN DAMAGE BURDEN IN A LARGE INTERNATIONAL MULTICENTER COHORT OF PATIENTS WITH BEHÇET’S SYNDROME: PRELIMINARY RESULTS OF THE PROBE STUDY

Author

Floris, A., primary, Chadli, S., additional, Lamouna, A., additional, Hegazy, M. T., additional, Yagiz Ozogul, Y., additional, Ozguler, Y., additional, Serpa Pinto, L., additional, Alikhani, M., additional, Oliveira, L., additional, Sota, J., additional, Lopalco, G., additional, Poddighe, D., additional, Kougkas, N., additional, Khabbazi Oskouei, A., additional, Laconi, R., additional, Wagner Silva de Souza, A., additional, Lo Monaco, A., additional, Espinosa, G., additional, Butendieck, R., additional, Govoni, M., additional, Issayeva, B., additional, Iannone, F., additional, Fabiani, C. M., additional, Cantarini, L., additional, Vasconcelos, C., additional, Shahram, F., additional, Correia, J., additional, Tazi Mezalek, Z., additional, Ragab, G., additional, Arnaud, L., additional, Cauli, A., additional, Hatemi, G., additional, and Piga, M., additional

Published
2023
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38. Avascular Necrosis Complicated by Osteomyelitis in a Lupus Patient With Active Renal Disease: A Case Report

Author

Nejadhosseinian Mohammad, Hadighi Pouya, Aghaghazvini Leila, Hakemi Monirsadat, Atef Yekta Reza, Akhlaghi Maassoumeh, Kavosi Hoda, Alikhani Majid, Loghman Maryam, Salehi Samira, Mozaffari Mohammad Ali, Babagoli Mazyar, Mobina Taghva Nakhjiri, and Faezi Seyedeh Tahereh

Subjects
case report, necrotizing fasciitis, osteomyelitis, osteonecrosis, systemic lupus erythematous, Medicine, Medicine (General), R5-920
Abstract

ABSTRACT This case highlights the importance of taking Systemic Lupus Erythematosus seriously and its possible concurrent musculoskeletal complications, as they can have significant health implications. Consulting and encouraging patients to adhere to the treatment is crucial. Although this case survived osteomyelitis without amputation, this outcome is rare and cannot be generalized.

Published
2025
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40. Adjusting for 30-hour undigested neutral detergent fiber in substitution of wheat straw and beet pulp for alfalfa hay and corn silage in the dairy cow diet: Chewing activities, diurnal feed intake, and ruminal fermentation

Author

Kahyani, A, Ghorbani, GR, Alikhani, M, Rafiee, H, Ramezani, O, Esfahani, MA, Ahmadi, F, Kahyani, A, Ghorbani, GR, Alikhani, M, Rafiee, H, Ramezani, O, Esfahani, MA, and Ahmadi, F

Abstract

This experiment investigated the effects of replacing alfalfa hay (AH) and corn silage (CS) with wheat straw (WS) and beet pulp (BP) in diets with similar forage 30-h undigested neutral detergent fiber (uNDF30) on chewing behavior and ruminal fermentation of lactating cows. Twelve multiparous Holstein cows (51 ± 3 kg/d of milk; days in milk = 97 ± 13; mean ± standard error) were housed in individual stalls and used in a replicated 3 × 3 Latin square design with 28-d periods. Experimental diets were (1) 0% forage uNDF30 from WS (WS0, contained 2% BP); (2) 50% forage uNDF30 from WS (WS50, contained 7.6% BP); and (3) 100% forage uNDF30 from WS (WS100, contained 12.4% BP). From 0 to 2 h after the morning feeding, there was a tendency observed for a quadratic effect on dry matter intake (DMI), with cows fed WS50 consuming the greatest amount of DM (9.19 kg). Later DMI (4 to 6 h and 6 to 24 h postfeeding) decreased as dietary proportion of WS and BP increased. Increasing WS and BP decreased eating behavior, but had no detected effect on rumination time (455 min/d), which resulted in a linear reduction in chewing time (the sum of eating and rumination activities). As WS and BP inclusion increased, the number of meals decreased linearly, whereas time between meals, eating rate, and meal size per kilogram of DM increased linearly. Increased dietary inclusion of WS and BP tended to decrease total ruminal VFA and resulted in a linear decrease in propionate but an increase in acetate proportion and ammonia-N concentration in the rumen. Overall, the substitution had no effect on rumination activity, possibly suggesting that a combination of WS and BP could be used in dairy cow rations as substitutes for high-quality forages when WS was added to maintain the uNDF30 level.

Published
2022

43. Global injury morbidity and mortality from 1990 to 2017: Results from the Global Burden of Disease Study 2017

Author

James, S, Castle, C, Dingels, Z, Fox, J, Hamilton, E, Liu, Z, S Roberts, N, Sylte, D, Henry, N, Legrand, K, Abdelalim, A, Abdoli, A, Abdollahpour, I, Abdulkader, R, Abedi, A, Abosetugn, A, Abushouk, A, Adebayo, O, Agudelo-Botero, M, Ahmad, T, Ahmed, R, Ahmed, M, Eddine Aichour, M, Alahdab, F, Alamene, G, Alanezi, F, Alebel, A, Alema, N, Alghnam, S, Al-Hajj, S, Ali, B, Ali, S, Alikhani, M, Alinia, C, Alipour, V, Aljunid, S, Almasi-Hashiani, A, Almasri, N, Altirkawi, K, Abdeldayem Amer, Y, Amini, S, Loreche Amit, A, Andrei, C, Ansari-Moghaddam, A, T Antonio, C, Yaw Appiah, S, Arabloo, J, Arab-Zozani, M, Arefi, Z, Aremu, O, Ariani, F, Arora, A, Asaad, M, Asghari, B, Awoke, N, Ayala Quintanilla, B, Ayano, G, Ayanore, M, Azari, S, Azarian, G, Badawi, A, Badiye, A, Bagli, E, Baig, A, Bairwa, M, Bakhtiari, A, Balachandran, A, Banach, M, Banerjee, S, Banik, P, Banstola, A, Barker-Collo, S, Barnighausen, T, Barrero, L, Barzegar, A, Bayati, M, Baye, B, Bedi, N, Behzadifar, M, Bekuma, T, Belete, H, Benjet, C, Bennett, D, Bensenor, I, Berhe, K, Bhardwaj, P, Bhat, A, Bhattacharyya, K, Bibi, S, Bijani, A, Bin Sayeed, M, Borges, G, Borzi, A, Boufous, S, Brazinova, A, Briko, N, Budhathoki, S, Car, J, Cardenas, R, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castelpietra, G, Catala-Lopez, F, Cerin, E, Chandan, J, Chanie, W, Chattu, S, Chattu, V, Chatziralli, I, Chaudhary, N, Cho, D, Kabir Chowdhury, M, Chu, D, Colquhoun, S, Constantin, M, Costa, V, Damiani, G, Daryani, A, Davila-Cervantes, C, Demeke, F, Demis, A, Demoz, G, Demsie, D, Derakhshani, A, Deribe, K, Desai, R, Nasab, M, Da Silva, D, Dibaji Forooshani, Z, Doyle, K, Driscoll, T, Dubljanin, E, Adema, B, Eagan, A, Eftekhari, A, Ehsani-Chimeh, E, Sayed Zaki, M, Elemineh, D, El-Jaafary, S, El-Khatib, Z, Ellingsen, C, Emamian, M, Endalew, D, Eskandarieh, S, Faris, P, Faro, A, Farzadfar, F, Fatahi, Y, Fekadu, W, Ferede, T, Fereshtehnejad, S, Fernandes, E, Ferrara, P, Feyissa, G, Filip, I, Fischer, F, Folayan, M, Foroutan, M, Francis, J, Franklin, R, Fukumoto, T, Geberemariyam, B, Gebre, A, Gebremedhin, K, Gebremeskel, G, Gebremichael, B, Gedefaw, G, Geta, B, Ghafourifard, M, Ghamari, F, Ghashghaee, A, Gholamian, A, Gill, T, Goulart, A, Grada, A, Grivna, M, Mohialdeen Gubari, M, Guimaraes, R, Guo, Y, Gupta, G, Haagsma, J, Hafezi-Nejad, N, Bidgoli, H, Hall, B, Hamadeh, R, Hamidi, S, Haro, J, Hasan, M, Hasanzadeh, A, Hassanipour, S, Hassankhani, H, Hassen, H, Havmoeller, R, Hayat, K, Hendrie, D, Heydarpour, F, Hijar, M, Ho, H, Hoang, C, Hole, M, Holla, R, Hossain, N, Hosseinzadeh, M, Hostiuc, S, Hu, G, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Inbaraj, L, Indriasih, E, Naghibi Irvani, S, Shariful Islam, S, Islam, M, Ivers, R, Jacobsen, K, Jahani, M, Jahanmehr, N, Jakovljevic, M, Jalilian, F, Jayaraman, S, Jayatilleke, A, Jha, R, John-Akinola, Y, Jonas, J, Joseph, N, Joukar, F, Jozwiak, J, Jungari, S, Jurisson, M, Kabir, A, Kadel, R, Kahsay, A, Kalankesh, L, Kalhor, R, Kamil, T, Kanchan, T, Kapoor, N, Karami, M, Kasaeian, A, Kassaye, H, Kavetskyy, T, Kebede, H, Keiyoro, P, Kelbore, A, Kelkay, B, Khader, Y, Khafaie, M, Khalid, N, Khalil, I, Khalilov, R, Khammarnia, M, Khan, E, Khan, M, Khanna, T, Khazaie, H, Shadmani, F, Khundkar, R, Kiirithio, D, Kim, Y, Kim, D, Kisa, A, Kisa, S, Komaki, H, M Kondlahalli, S, Korshunov, V, Koyanagi, A, G Kraemer, M, Krishan, K, Bicer, B, Kugbey, N, Kumar, V, Kumar, N, Kumar, G, Kumar, M, Kumaresh, G, Kurmi, O, Kuti, O, Vecchia, C, Lami, F, Lamichhane, P, Lang, J, Lansingh, V, Laryea, D, Lasrado, S, Latifi, A, Lauriola, P, Leasher, J, Huey Lee, S, Lenjebo, T, Levi, M, Li, S, Linn, S, Liu, X, Lopez, A, Lotufo, P, Lunevicius, R, Lyons, R, Madadin, M, El Razek, M, Mahotra, N, Majdan, M, Majeed, A, Malagon-Rojas, J, Maled, V, Malekzadeh, R, Malta, D, Manafi, N, Manafi, A, Manda, A, Manjunatha, N, Mansour-Ghanaei, F, Mansouri, B, Mansournia, M, Maravilla, J, March, L, Mason-Jones, A, Masoumi, S, Massenburg, B, Maulik, P, Meles, G, Melese, A, Melketsedik, Z, N Memiah, P, Mendoza, W, Menezes, R, Mengesha, M, Meretoja, T, Meretoja, A, Merie, H, Mestrovic, T, Miazgowski, B, Miazgowski, T, Miller, T, Mini, G, Mirica, A, Mirrakhimov, E, Mirzaei-Alavijeh, M, Mithra, P, Moazen, B, Moghadaszadeh, M, Mohamadi, E, Mohammad, Y, Mohammad, K, Darwesh, A, Gholi Mezerji, N, Mohammadian-Hafshejani, A, Mohammadoo-Khorasani, M, Mohammadpourhodki, R, Mohammed, S, Mohammed, J, Mohebi, F, Molokhia, M, Monasta, L, Moodley, Y, Moosazadeh, M, Moradi, M, Moradi, G, Moradi-Lakeh, M, Moradpour, F, Morawska, L, Velasquez, I, Morisaki, N, Morrison, S, Mossie, T, Muluneh, A, Murthy, S, Musa, K, Mustafa, G, Nabhan, A, Nagarajan, A, Naik, G, Naimzada, M, Najafi, F, Nangia, V, Nascimento, B, Naserbakht, M, Nayak, V, Ndwandwe, D, Negoi, I, Ngunjiri, J, Nguyen, C, Thi Nguyen, H, Nikbakhsh, R, Anggraini Ningrum, D, Nnaji, C, Nyasulu, P, Ogbo, F, Oghenetega, O, Oh, I, Okunga, E, Olagunju, A, Olagunju, T, Bali, A, Onwujekwe, O, Asante, K, Orpana, H, Ota, E, Otstavnov, N, Otstavnov, S, Mahesh, P, Padubidri, J, Pakhale, S, Pakshir, K, Panda-Jonas, S, Park, E, Patel, S, Pathak, A, Pati, S, Patton, G, Paulos, K, Peden, A, Filipino Pepito, V, Pereira, J, Pham, H, Phillips, M, Pinheiro, M, Polibin, R, Polinder, S, Poustchi, H, Prakash, S, Angga Pribadi, D, Puri, P, Syed, Z, Rabiee, M, Rabiee, N, Radfar, A, Rafay, A, Rafiee, A, Rafiei, A, Rahim, F, Rahimi, S, Rahimi-Movaghar, V, Rahman, M, Rajabpour-Sanati, A, Rajati, F, Rakovac, I, Ranganathan, K, Rao, S, Rashedi, V, Rastogi, P, Rathi, P, Rawaf, S, Rawal, L, Rawassizadeh, R, Renjith, V, N Renzaho, A, Resnikoff, S, Rezapour, A, Ribeiro, A, Rickard, J, Rios Gonzalez, C, Ronfani, L, Roshandel, G, Saad, A, Sabde, Y, Sabour, S, Saddik, B, Safari, S, Safari-Faramani, R, Safarpour, H, Safdarian, M, Sajadi, S, Salamati, P, Salehi, F, Zahabi, S, Rashad Salem, M, Salem, H, Salman, O, Salz, I, Samy, A, Sanabria, J, Riera, L, Santric Milicevic, M, Sarker, A, Sarveazad, A, Sathian, B, Sawhney, M, Sawyer, S, Saxena, S, Sayyah, M, Schwebel, D, Seedat, S, Senthilkumaran, S, Sepanlou, S, Seyedmousavi, S, Sha, F, Shaahmadi, F, Shahabi, S, Shaikh, M, Shams-Beyranvand, M, Shamsizadeh, M, Sharif-Alhoseini, M, Sharifi, H, Sheikh, A, Shigematsu, M, Shin, J, Shiri, R, Siabani, S, Sigfusdottir, I, Singh, P, Singh, J, Sinha, D, Smarandache, C, R Smith, E, Soheili, A, Soleymani, B, Soltanian, A, Soriano, J, Sorrie, M, Soyiri, I, Stein, D, Stokes, M, Sufiyan, M, Rasul Suleria, H, Sykes, B, Tabares-Seisdedos, R, Tabb, K, Taddele, B, Tadesse, D, Tamiru, A, Tarigan, I, Tefera, Y, Tehrani-Banihashemi, A, Tekle, M, Tekulu, G, Tesema, A, Tesfay, B, Thapar, R, Tilahune, A, Tlaye, K, Tohidinik, H, Topor-Madry, R, Tran, B, Tran, K, Tripathy, J, Tsai, A, Car, L, Ullah, S, Ullah, I, Umar, M, Unnikrishnan, B, Upadhyay, E, Uthman, O, Valdez, P, Vasankari, T, Venketasubramanian, N, Violante, F, Vlassov, V, Waheed, Y, Weldesamuel, G, Werdecker, A, Wiangkham, T, Wolde, H, Woldeyes, D, Wondafrash, D, Wondmeneh, T, Wondmieneh, A, Wu, A, Yadav, R, Yadollahpour, A, Yano, Y, Yaya, S, Yazdi-Feyzabadi, V, Yip, P, Yisma, E, Yonemoto, N, Yoon, S, Youm, Y, Younis, M, Yousefi, Z, Yu, Y, Yu, C, Yusefzadeh, H, Moghadam, T, Zaidi, Z, Zaman, S, Zamani, M, Zamanian, M, Zandian, H, Zarei, A, Zare, F, Zhang, Z, Zhang, Y, Zodpey, S, Dandona, L, Dandona, R, Degenhardt, L, Dharmaratne, S, Hay, S, Mokdad, A, Reiner Jr, R, Sartorius, B, Vos, T, James S. 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Abstract

Background: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. Methods: We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings: In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation: Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.

Published
2020

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