4 results on '"Allard, R. V."'
Search Results
2. Point‐of‐care ultrasound use in emergencies: what every anaesthetist should know.
- Author
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Haskings, E. M., Eissa, M., Allard, R. V., MirGhassemi, A., McFaul, C. M., and Miller, E. C.
- Subjects
ULTRASONIC imaging ,POINT-of-care testing ,PLEURAL effusions ,ANESTHESIOLOGISTS ,PNEUMOTHORAX ,VENTRICULAR ejection fraction ,PERICARDIAL effusion - Abstract
Summary: Point‐of‐care ultrasound has been embraced by anaesthetists as an invaluable tool for rapid diagnosis of haemodynamic instability, to ensure procedural safety and monitor response to treatments. Increasingly available, affordable and portable, with emerging evidence of improved patient outcomes, point‐of‐care ultrasound has become a valuable tool in the emergency setting. This state‐of‐the‐art review describes the feasibility of point‐of‐care ultrasound practice, training and maintenance of competence. It also describes the many uses of point‐of‐care ultrasound for the anaesthetist and describes the most salient point‐of‐care ultrasound views for anaesthetic emergencies including: undifferentiated shock; hypoxemia; and trauma. Procedural safety is also discussed in addition to relevant important governance aspects. Cardiac function should be assessed using the parasternal long axis, parasternal short basal/mid‐papillary/apical, apical four chamber and subcostal four chamber views, and should include a visual estimation of global left ventricular ejection fraction. Other cardiovascular conditions that can be identified using point‐of‐care ultrasound include: pericardial effusion; cardiac tamponade; and pulmonary embolism. Pulmonary emergency conditions that can be diagnosed using point‐of‐care ultrasound include pneumothorax; pleural effusion; and interstitial syndrome. The extended focused assessment with sonography for trauma examination may of value in patients who are hypotensive in order to identify intra‐abdominal haemorrhage, pneumothoraces and haemothoraces. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality.
- Author
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Devereaux, P. J., Lamy, A., Chan, M. T. V., Allard, R. V., Lomivorotov, V. V., Landoni, G., Zheng, H., Paparella, D., McGillion, M. H., Belley-Cdtd, E. P., Parlow, J. L., Underwood, M. J., Wang, C. Y., Dvirnik, N., Marat, A., Fominskiy, E., Choi, S., Fremes, S., Monaco, F., and Urrutia, G.
- Subjects
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TROPONIN I , *CARDIAC surgery , *MYOCARDIAL injury , *MYOCARDIAL infarction , *REGRESSION analysis , *CARDIOPULMONARY bypass , *MYOCARDIAL reperfusion - Abstract
BACKGROUND Consensus recommendations regarding the threshold levels of cardiac troponin elevations for the definition of perioperative myocardial infarction and clinically important periprocedural myocardial injury in patients undergoing cardiac surgery range widely (from >10 times to ≥70 times the upper reference limit for the assay). Limited evidence is available to support these recommendations. METHODS We undertook an international prospective cohort study involving patients 18 years of age or older who underwent cardiac surgery. High-sensitivity cardiac troponin I measurements (upper reference limit, 26 ng per liter) were obtained 3 to 12 hours after surgery and on days 1, 2, and 3 after surgery. We performed Cox analyses using a regression spline that explored the relationship between peak troponin measurements and 30-day mortality, adjusting for scores on the European System for Cardiac Operative Risk Evaluation II (which estimates the risk of death after cardiac surgery on the basis of 18 variables, including age and sex). RESULTS Of 13,862 patients included in the study, 296 (2.1%) died within 30 days after surgery. Among patients who underwent isolated coronary-artery bypass grafting or aortic-valve replacement or repair, the threshold troponin level, measured within 1 day after surgery, that was associated with an adjusted hazard ratio of more than 1.00 for death within 30 days was 5670 ng per liter (95% confidence interval [CI], 1045 to 8260), a level 218 times the upper reference limit. Among patients who underwent other cardiac surgery, the corresponding threshold troponin level was 12,981 ng per liter (95% CI, 2673 to 16,591), a level 499 times the upper reference limit. CONCLUSIONS The levels of high-sensitivity troponin I after cardiac surgery that were associated with an increased risk of death within 30 days were substantially higher than levels currently recommended to define clinically important periprocedural myocardial injury. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
4. High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality
- Author
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P J, Devereaux, Andre, Lamy, Matthew T V, Chan, René V, Allard, Vladimir V, Lomivorotov, Giovanni, Landoni, Hong, Zheng, Domenico, Paparella, Michael H, McGillion, Emilie P, Belley-Côté, Joel L, Parlow, Malcolm J, Underwood, Chew Yin, Wang, Nazari, Dvirnik, Marat, Abubakirov, Evgeny, Fominskiy, Stephen, Choi, Stephen, Fremes, Fabrizio, Monaco, Gerard, Urrútia, Marialuz, Maestre, Ludhmila A, Hajjar, Graham S, Hillis, Nicholas L, Mills, Vito, Margari, Joseph D, Mills, J Stephen, Billing, Emily, Methangkool, Carisi A, Polanczyk, Roberto, Sant'Anna, Dmitry, Shukevich, David, Conen, Peter A, Kavsak, Matthew J, McQueen, Katheryn, Brady, Jessica, Spence, Yannick, Le Manach, Rajibul, Mian, Shun Fu, Lee, Shrikant I, Bangdiwala, Sara, Hussain, Flavia K, Borges, Shirley, Pettit, Jessica, Vincent, Gordon H, Guyatt, Salim, Yusuf, Joseph S, Alpert, Harvey D, White, Richard P, Whitlock, Allison, Serra, Devereaux, P. J., Lamy, A., Chan, M. T. V., Allard, R. V., Lomivorotov, V. V., Landoni, G., Zheng, H., Paparella, D., Mcgillion, M. H., Belley-Cote, E. P., Parlow, J. L., Underwood, M. J., Wang, C. Y., Dvirnik, N., Abubakirov, M., Fominskiy, E., Choi, S., Fremes, S., Monaco, F., Urrutia, G., Maestre, M., Hajjar, L. A., Hillis, G. S., Mills, N. L., Margari, V., Mills, J. D., Billing, J. S., Methangkool, E., Polanczyk, C. A., Sant'Anna, R., Shukevich, D., Conen, D., Kavsak, P. A., Mcqueen, M. J., Brady, K., Spence, J., Le Manach, Y., Mian, R., Lee, S. F., Bangdiwala, S. I., Hussain, S., Borges, F. K., Pettit, S., Vincent, J., Guyatt, G. H., Yusuf, S., Alpert, J. S., White, H. D., and Whitlock, R. P.
- Subjects
Male ,heart infarction ,adverse event ,Myocardial Infarction ,surgery ,Postoperative Complications ,blood ,coronary artery bypass graft ,Reference Values ,Humans ,postoperative complication ,human ,Prospective Studies ,Cardiac Surgical Procedures ,Coronary Artery Bypass ,Aged ,Troponin I ,reference value ,clinical trial ,General Medicine ,Middle Aged ,biological marker ,mortality ,heart surgery ,multicenter study ,Aortic Valve ,Female ,Biomarkers ,prospective study - Abstract
BACKGROUND Consensus recommendations regarding the threshold levels of cardiac troponin elevations for the definition of perioperative myocardial infarction and clinically important periprocedural myocardial injury in patients undergoing cardiac surgery range widely (from >10 times to >= 70 times the upper reference limit for the assay). Limited evidence is available to support these recommendations. METHODS We undertook an international prospective cohort study involving patients 18 years of age or older who underwent cardiac surgery. High-sensitivity cardiac troponin I measurements (upper reference limit, 26 ng per liter) were obtained 3 to 12 hours after surgery and on days 1, 2, and 3 after surgery. We performed Cox analyses using a regression spline that explored the relationship between peak troponin measurements and 30-day mortality, adjusting for scores on the European System for Cardiac Operative Risk Evaluation II (which estimates the risk of death after cardiac surgery on the basis of 18 variables, including age and sex). RESULTS Of 13,862 patients included in the study, 296 (2.1%) died within 30 days after surgery. Among patients who underwent isolated coronary-artery bypass grafting or aortic-valve replacement or repair, the threshold troponin level, measured within 1 day after surgery, that was associated with an adjusted hazard ratio of more than 1.00 for death within 30 days was 5670 ng per liter (95% confidence interval [CI], 1045 to 8260), a level 218 times the upper reference limit. Among patients who underwent other cardiac surgery, the corresponding threshold troponin level was 12,981 ng per liter (95% CI, 2673 to 16,591), a level 499 times the upper reference limit. CONCLUSIONS The levels of high-sensitivity troponin I after cardiac surgery that were associated with an increased risk of death within 30 days were substantially higher than levels currently recommended to define clinically important periprocedural myocardial injury. (Funded by the Canadian Institutes of Health Research and others; VISION Cardiac Surgery ClinicalTrials.gov number, NCT01842568.)
- Published
- 2022
- Full Text
- View/download PDF
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