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1,040 results on '"Allergens toxicity"'

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1. Predicting points of departure and potency categories for fragrance ingredients by integrating OECD in vitro models.

2. The dimer effect: A refinement approach towards skin sensitization assessment in-chemico using Amino acid Derivative Reactivity Assay.

3. The integrin receptor beta 7 subunit mediates airway remodeling and hyperresponsiveness in allergen exposed mice.

4. Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency.

5. Benchmarking of BMDC assay and related QSAR study for identifying sensitizing chemicals.

6. The transcriptomic signature of respiratory sensitizers using an alveolar model.

7. The inter-laboratory validation study of EpiSensA for predicting skin sensitization potential.

8. Lung Gene Expression Suggests Roles for Interferon-Stimulated Genes and Adenosine Deaminase Acting against RNA-1 in Pathologic Responses to Diisocyanate.

9. Identification of toxicity-induced biomarkers in human non-immune airway cells exposed to respiratory sensitizers: A mechanistic approach.

10. Use of guinea pig data to obtain starting points for skin sensitisation risk assessment - A commentary.

11. Identification of true chemical respiratory allergens: Current status, limitations and recommendations.

12. Prediction of skin sensitization using machine learning.

13. Investigating sensitization activity of azobenzene disperse dyes via the Direct Peptide Reactivity Assay (DPRA).

14. Evaluation of evidence for interaction between PM2.5 and aeroallergens on childhood asthma exacerbation in Philadelphia, PA, 2011 to 2016.

15. A comparative proteomics analysis of four contact allergens in THP-1 cells shows distinct alterations in key metabolic pathways.

16. Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes.

17. Role of miR-24-3p and miR-146a-5p in dendritic cells' maturation process induced by contact sensitizers.

18. Biological effects triggered by chemical respiratory sensitizers on THP-1 monocytic cells.

19. Biological impact of sequential exposures to allergens and ultrafine particle-rich combustion aerosol on human bronchial epithelial BEAS-2B cells at the air liquid interface.

20. Trajectory of neutrophilic responses in a mouse model of pollutant-aggravated allergic asthma.

21. The Safety Assessment of Cosmetic Perfumes by Using In Chemico and In Vitro Methods in Combination with GC-MS/MS Analysis.

22. Toxicity and Mechanisms of Engineered Nanoparticles in Animals with Established Allergic Asthma.

23. Specificity of the local lymph node assay (LLNA) for skin sensitisation.

24. Challenges in the classification of chemical respiratory allergens based on human data: Case studies of 2-hydroxyethylmethacrylate (HEMA) and 2-hydroxypropylmethacrylate (HPMA).

25. Assessing the risk of induction of skin sensitization to plant protection products: A quantitative approach.

26. Aggravation of food allergy symptoms by treatment with acrylamide in a mouse model.

27. Estimating uncertainty in LLNA EC3 data and its impact on regulatory classifications.

28. Multidimensional Analysis of Lung Lymph Nodes in a Mouse Model of Allergic Lung Inflammation following P M 2.5 and Indeno[1,2,3- cd ]pyrene Exposure.

29. Propylene glycol, skin sensitisation and allergic contact dermatitis: A scientific and regulatory conundrum.

30. Reduced specificity for the local lymph node assay for lipophilic chemicals: Implications for the validation of new approach methods for skin sensitization.

31. Mild allergic airways responses to an environmental mixture increase cardiovascular risk in rats.

32. Alteration of glycosphingolipid metabolism by ozone is associated with exacerbation of allergic asthma characteristics in mice.

33. Di-(2-ethylhexyl) phthalate aggravates fine particulate matter-induced asthma in weanling mice due to T follicular helper cell-dependent response.

34. Ozone impairs endogenous compensatory responses in allergic asthma.

35. The phenomenon of thunderstorm asthma in Bavaria, Southern Germany: a statistical approach.

36. Oral Cadmium Intake Enhances Contact Allergen-induced Skin Reaction in Rats.

37. Sulfur dioxide-enhanced asthma susceptibility is involved with inhibition of bitter taste transduction in mouse lung.

38. Acceptable surface limits (ASLs) of skin sensitizers derived from the local lymph node assay (LLNA): BrdU-ELISA EC1.6 values and their relationships to known sensitization potency information.

39. "From Protein Toxins to Applied Toxicological Testing" virtual workshop identifies the need for a bioinformatic framework to assess novel food protein safety.

40. The association between outdoor allergens - pollen, fungal spore season and high asthma admission days in children and adolescents.

41. Nature-derived epoxy resins: Synthesis, allergenicity, and thermosetting properties of pinoresinol diglycidyl ether.

42. Associations between grass pollen exposures in utero and in early life with food allergy in 12-month-old infants.

43. Skin sensitization quantitative QSAR models based on mechanistic structural alerts.

44. Methyl methacrylate and respiratory sensitisation: a comprehensive review.

45. Validation of Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) approaches as alternatives to skin sensitization risk assessment.

46. Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma.

47. IL-33 receptor expression on myeloid and plasmacytoid dendritic cells after allergen challenge in patients with allergic rhinitis.

48. OGR1-dependent regulation of the allergen-induced asthma phenotype.

49. Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization.

50. Insights into the Photodegradation of the Contact Allergen Fragrance Cinnamyl Alcohol: Kinetics, Mechanism, and Toxicity.

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