13 results on '"Almazán V"'
Search Results
2. Estudio de contactos tras exposición accidental a tuberculosis en un Servicio de Urgencias
- Author
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Paredes Rizo, M.ª Luisa, Rescalvo Santiago, F., De Paula Ortiz, M., De Benito Gutiérrez, J., Fernández Almazán, V., and Lamas Alonso, A.
- Subjects
health workers ,tuberculosis ,occupational disease ,personal sanitario ,enfermedad profesional - Abstract
Introducción: La tuberculosis ha sido una de las grandes causas de morbimortalidad a nivel mundial y sigue constituyendo hoy día un grave problema de salud pública. La Organización Mundial de la Salud (OMS) estima que en 2014 se produjeron 9. 6 millones de enfermos y 1. 5 millones de muertes por tuberculosis, además un tercio de la población mundial presenta actualmente infección tuberculosa latente (ITL). La tuberculosis es considerada enfermedad profesional en los trabajadores que contraen la enfermedad a causa de su trabajo y es un riesgo laboral significativo en los trabajadores sanitarios. Los Servicios de Prevención son los encargados del manejo de este riesgo así como su abordaje para controlar la tuberculosis en el medio laboral. Objetivo: Determinar la prevalencia de infección tuberculosa latente en los trabajadores del Servicio de Urgencias de un hospital general tras una exposición accidental sin medidas de protección adecuadas. Analizar el abordaje preventivo en el manejo de este riesgo profesional. Metodología: Estudio descriptivo transversal realizado en trabajadores sanitarios que participaron en un estudio de contactos durante 3 meses. Como método de identificación de los infectados se utiliza la prueba de la tuberculina y la determinación de Quantiferon. Resultados: De los 181 trabajadores estudiados 141 se siguieron en el Servicio de Prevención de Riesgos Laborales. Se diagnosticaron 24 trabajadores con infección latente tuberculosa y se realizó quimioprofilaxis a 10 de ellos. De los 181 trabajadores estudiados, 103 tenían reconocimiento previo. El 57% tenía documentado una prueba de tuberculina previa. La prevalencia de infección latente tuberculosa en los trabajadores estudiados es de 13,3% y en este periodo de tiempo no ha habido ninguna infección reciente. Conclusiones: La tuberculosis sigue siendo un riesgo profesional en los trabajadores sanitarios. Conocer la incidencia previa de infección tuberculosa latente en nuestros trabajadores mediante programas de cribado, permite la aplicación precoz de medidas preventivas que eviten la transmisión y posibles retrasos en los diagnósticos, paso fundamental para evitar el contagio y desarrollo de nuevas infecciones. Los Servicios de Prevención de Riesgos Laborales deberían mejorar sus programas de vigilancia y cribado para controlar este riesgo adecuadamente. Introduction: Tuberculosis has been one of the major causes of morbidity and mortality worldwide and is still regarded as a serious public health problem. The World Health Organization (WHO) estimates that there were 9. 6 million patients in 2014 and 1. 5 million deaths from tuberculosis. It means that a third of the world population currently presents latent tuberculosis infection (LTBI). The TB is considered an occupational disease and is a significant occupational hazard among health care workers. Prevention services are responsible not only for managing this risk and its approach but also for controlling TB at the workplace. Objective: To determine the prevalence of latent tuberculosis infection within the workers of the Emergency Department in a general hospital and then analyze the preventive approach in the management of this occupational hazard. Methodology: Cross-sectional study conducted in health care workers who participated in a study for 3 months. Those affected were identified by the tuberculin test and the Quantiferon to identify the infected people (blood test that detects the bacteria that causes tuberculosis). Results: 181 workers were studied. 141 were monitored in the Occupational risk Department. 24 workers were diagnosed with latent tuberculosis infection. Chemoprophylaxis was performed in 10 workers. 103 had previous occupational medical examinations. 57% documented previous tuberculin test. The prevalence of latent TB infection in the workers studied is 13. 3% and there has been no recent infection during this time. Conclusions: Tuberculosis remains an occupational hazard for health workers. By knowing the previous incidence of latent TB infection among our workers through screening programs, we can take preventive measures in order to avoid transmission and possible delays in diagnosis. This procedure is crucial to avoid the spread and the development of new infections. Occupational Health and Safety Departments should improve their surveillance and screening programs to properly manage this risk.
- Published
- 2016
3. Estudio de contactos tras exposición accidental a tuberculosis en un Servicio de Urgencias
- Author
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Paredes Rizo, Mª Luisa, Rescalvo Santiago, Fernando, De Paula Ortiz, M., De Benito Gutiérrez, J., Fernández Almazán, V., and Lamas Alonso, A.
- Subjects
lcsh:Internal medicine ,lcsh:R ,Enfermedad profesional ,lcsh:Medicine ,Occupational disease ,Health workers ,Personal sanitario ,health workers ,lcsh:RC963-969 ,tuberculosis ,occupational disease ,lcsh:Industrial medicine. Industrial hygiene ,Tuberculosis ,lcsh:RC31-1245 - Abstract
Originales [ES] Introducción: La tuberculosis ha sido una de las grandes causas de morbimortalidad a nivel mundial y sigue constituyendo hoy día un grave problema de salud pública. La Organización Mundial de la Salud (OMS) estima que en 2014 se produjeron 9.6 millones de enfermos y 1.5 millones de muertes por tuberculosis, además un tercio de la población mundial presenta actualmente infección tuberculosa latente (ITL). La tuberculosis es considerada enfermedad profesional en los trabajadores que contraen la enfermedad a causa de su trabajo y es un riesgo laboral significativo en los trabajadores sanitarios. Los Servicios de Prevención son los encargados del manejo de este riesgo así como su abordaje para controlar la tuberculosis en el medio laboral. Objetivo: Determinar la prevalencia de infección tuberculosa latente en los trabajadores del Servicio de Urgencias de un hospital general tras una exposición accidental sin medidas de protección adecuadas. Analizar el abordaje preventivo en el manejo de este riesgo profesional. Metodología: Estudio descriptivo transversal realizado en trabajadores sanitarios que participaron en un estudio de contactos durante 3 meses. Como método de identificación de los infectados se utiliza la prueba de la tuberculina y la determinación de Quantiferon. Resultados: De los 181 trabajadores estudiados 141 se siguieron en el Servicio de Prevención de Riesgos Laborales. Se diagnosticaron 24 trabajadores con infección latente tuberculosa y se realizó quimioprofilaxis a 10 de ellos. De los 181 trabajadores estudiados, 103 tenían reconocimiento previo. El 57% tenía documentado una prueba de tuberculina previa. La prevalencia de infección latente tuberculosa en los trabajadores estudiados es de 13,3% y en este periodo de tiempo no ha habido ninguna infección reciente. Conclusiones: La tuberculosis sigue siendo un riesgo profesional en los trabajadores sanitarios. Conocer la incidencia previa de infección tuberculosa latente en nuestros trabajadores mediante programas de cribado, permite la aplicación precoz de medidas preventivas que eviten la transmisión y posibles retrasos en los diagnósticos, paso fundamental para evitar el contagio y desarrollo de nuevas infecciones. Los Servicios de Prevención de Riesgos Laborales deberían mejorar sus programas de vigilancia y cribado para controlar este riesgo adecuadamente.[EN] Introduction: Tuberculosis has been one of the major causes of morbidity and mortality worldwide and is still regarded as a serious public health problem. The World Health Organization (WHO) estimates that there were 9.6 million patients in 2014 and 1.5 million deaths from tuberculosis. It means that a third of the world population currently presents latent tuberculosis infection (LTBI). The TB is considered an occupational disease and is a significant occupational hazard among health care workers. Prevention services are responsible not only for managing this risk and its approach but also for controlling TB at the workplace. Objective: To determine the prevalence of latent tuberculosis infection within the workers of the Emergency Department in a general hospital and then analyze the preventive approach in the management of this occupational hazard. Methodology: Cross-sectional study conducted in health care workers who participated in a study for 3 months. Those affected were identified by the tuberculin test and the Quantiferon to identify the infected people (blood test that detects the bacteria that causes tuberculosis). Results: 181 workers were studied. 141 were monitored in the Occupational risk Department. 24 workers were diagnosed with latent tuberculosis infection. Chemoprophylaxis was performed in 10 workers. 103 had previous occupational medical examinations. 57% documented previous tuberculin test. The prevalence of latent TB infection in the workers studied is 13.3% and there has been no recent infection during this time. Conclusions: Tuberculosis remains an occupational hazard for health workers. By knowing the previous incidence of latent TB infection among our workers through screening programs, we can take preventive measures in order to avoid transmission and possible delays in diagnosis. This procedure is crucial to avoid the spread and the development of new infections. Occupational Health and Safety Departments should improve their surveillance and screening programs to properly manage this risk. No
- Published
- 2016
4. Screening of Ionic Liquids for Pretreatment of Taiwan Grass in Q-Tube Minireactors for Improving Bioethanol Production
- Author
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Merino, O., primary, Almazán, V., additional, Martínez-Palou, R., additional, and Aburto, J., additional
- Published
- 2016
- Full Text
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5. Estudio de contactos tras exposición accidental a tuberculosis en un Servicio de Urgencias.
- Author
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Maria Luisa, Paredes Rizo, Santiago F., Rescalvo, Ortiz M., De Paula, Gutiérrez J., De Benito, Almazán V., Fernández, and Alonso A., Lamas
- Abstract
Copyright of Medicina y Seguridad del Trabajo is the property of Escuela Nacional de Medicina del Trabajo - Instituto de Salud Carlos III and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
6. Carta tectónica de México (Version para microcomputadoras personales)
- Author
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R.J. Padilla, V.V. González Pacheco, R. Martínez Serrano, E. Almazán V., G. Carrasco NUñez, L. Silva Mora, E. González Partida, V. Torres Rodríguez, A. Herrera Najera, R. Uribe Afif, and R. Ferreiro Mineiro
- Subjects
tectónica ,cartas ,méxico ,Geophysics. Cosmic physics ,QC801-809 - Abstract
El proyecto "CARTA TECTONICA DE MEXICO" es el resultado de la integración de la información geológica y tectónica publicada en los últimos años. Esta compilación procede de diversas fuentes, a escalas diferentes, de las que se seleccionaron aquellos trabajos con datos de campo bien documentados. Se evitaron aquellos trabajos especulativos que no tenían un soporte científico sólido, o bien aquellos en los que las estructuras mostradas no estaban plenamente comprobadas.
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- 1989
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7. El fraile Trobador. Zeit, Leben und Werk des Diego de Valencia de León (1350?–1412?). Analecta Romanica (Heft 28) Wolf-Dieter Lange
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Almazán, V.
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- 1972
8. Carta tectónica de México (Version para microcomputadoras personales)
- Author
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Padilla, R.J., primary, González Pacheco, V.V., additional, Martínez Serrano, R., additional, Almazán V., E., additional, Carrasco NUñez, G., additional, Silva Mora, L., additional, González Partida, E., additional, Torres Rodríguez, V., additional, Herrera Najera, A., additional, Uribe Afif, R., additional, and Ferreiro Mineiro, R., additional
- Published
- 1989
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9. Dietary bisphenols exposure as an influencing factor of body mass index.
- Author
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Gálvez-Ontiveros Y, Monteagudo C, Giles-Mancilla M, Muros JJ, Almazán V, Martínez-Burgos MA, Samaniego-Sánchez C, Salcedo-Bellido I, Rivas A, and Zafra-Gómez A
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- Humans, Female, Male, Child, Spain epidemiology, Child, Preschool, Overweight epidemiology, Diet statistics & numerical data, Sulfones, Environmental Pollutants, Case-Control Studies, Obesity epidemiology, Phenols analysis, Benzhydryl Compounds, Body Mass Index, Dietary Exposure analysis, Dietary Exposure adverse effects
- Abstract
Background: Over the past three decades, there has been a significant increase in the prevalence and incidence of overweight and obesity worldwide. The obesogen hypothesis suggests that certain external agents may affect pathways related to fat accumulation and energy balance by stimulating fat cell differentiation and proliferation. Previous research has indicated that exposure to bisphenol A (BPA) and some of its analogues may influence fat accumulation by promoting the transformation of preadipocytes into adipocytes. This study aimed to assess the possible contribution of dietary bisphenol exposure to the odds of developing overweight and obesity in a sample of Spanish children according to sex., Methods: Dietary and anthropometric data were collected from 179 controls and 124 cases schoolchildren aged 3-12 years. Dietary exposure to BPA and bisphenol S (BPS) was assessed using a food consumption frequency questionnaire. Logistic regression models were used to assess the influence of dietary exposure to bisphenols on overweight and obesity stratified by sex., Results: For females, cases had significantly higher exposure to BPA from meat and eggs compared to controls (median = 319.55, interquartile range (IQR) = 176.39-381.01 vs 231.79 (IQR) = 162.11-350.19, p-value = 0.046). Diet quality was higher for controls (6.21 (2.14) vs 4.80 (2.24) p < 0.001) among males independently of a high or low exposure to bisphenols. However, higher diet quality was observed for female controls with an high exposure of total bisphenols (6.79 (2.04) vs 5.33 (2.02) p = 0.031). Females exposed to high levels of BPA from meat and eggs had higher likelihood of being overweight and obese (adjusted Odds Ratio = 2.70, 95% confidence interval = 1.00 - 7.32). However, no consistent associations were found in males., Conclusions: High BPA levels from meat and eggs were positively associated with overweight and obesity in females. The dietary intake of BPA in the schoolchildren in the present study was much higher than the acceptable daily intake established by EFSA for the last year., (© 2024. The Author(s).)
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- 2024
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10. Rational application of the ESPGHAN 2022 recommendations for the follow-up of the paediatric coeliac patient: consensus document of scientific societies (SEGHNP, AEPAP, SEPEAP, SEEC, AEG, SEPD, SEMFYC, SEMG and SEMERGEN).
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Roman E, Barrio J, Cilleruelo ML, Torres R, Almazán V, Coronel C, Espin B, Martinez-Ojinaga E, Solís DP, Moreno MA, Reyes J, Salazar LF, Farrais S, Castillejo G, Fontanillas N, Noguerol M, Prieto A, and Donat YE
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- Humans, Child, Adolescent, Diet, Gluten-Free, Aftercare methods, Aftercare standards, Transition to Adult Care standards, Societies, Medical, Patient Compliance, Celiac Disease therapy
- Abstract
Coeliac disease is a common condition for which the only current treatment is a gluten-free diet. Adherence to this diet is not always easy and is associated with a reduction in quality of life for the patient and their family. Non-adherence is associated with complications of varying severity. The lack of control at the outpatient care level in a high percentage of these patients evinces the need to improve follow-up protocols and the approach to care delivery with coordination of paediatric gastroenterology units (PGU) and primary care paediatricians. With this aim in mind, the present document was developed by consensus to offer a set of recommendations adapted to our region, based on the recent recommendations published by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), and with participation of the pertinent scientific societies, including those concerning the adult population, for the management and follow-up of adolescents and the transition to adult care., (Copyright © 2024 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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11. Increased levels of regulatory T cells and IL-10-producing regulatory B cells are linked to improved clinical outcome in Parkinson's disease: a 1-year observational study.
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Arce-Sillas A, Álvarez-Luquín DD, Leyva-Hernández J, Montes-Moratilla E, Vivas-Almazán V, Pérez-Correa C, Rodríguez-Ortiz U, Espinosa-Cárdenas R, Fragoso G, Sciutto E, and Adalid-Peralta L
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- Humans, Male, Female, Middle Aged, Aged, Follow-Up Studies, Parkinson Disease immunology, Parkinson Disease blood, T-Lymphocytes, Regulatory immunology, Interleukin-10 immunology, Interleukin-10 blood, B-Lymphocytes, Regulatory immunology
- Abstract
Whilst the contribution of peripheral and central inflammation to neurodegeneration in Parkinson's disease and the role of the immune response in this disorder are well known, the effects of the anti-inflammatory response on the disease have not been described in depth. This study is aimed to assess the changes in the regulatory/inflammatory immune response in recently diagnosed, untreated PD patients and a year after. Twenty-one PD patients and 19 healthy controls were included and followed-up for 1 year. The levels of immunoregulatory cells (CD4+ Tregs, Bregs, and CD8+ Tregs); classical, nonclassical, and intermediate monocytes, and proinflammatory cells (Th1, Th2, and Th17) were measured by flow cytometry. Cytokine levels were determined by ELISA. Clinical follow-up was based on the Hoehn & Yahr and UDPRS scales. Our results indicate that the regulatory response in PD patients on follow-up was characterized by increased levels of active Tregs, functional Tregs, TR1, IL-10-producing functional Bregs, and IL-10-producing classical monocytes, along with decreased counts of Bregs and plasma cells. With respect to the proinflammatory immune response, peripheral levels of Th1 IFN-γ+ cells were decreased in treated PD patients, whilst the levels of CD4+ TBET+ cells, HLA-DR+ intermediate monocytes, IL-6, and IL-4 were increased after a 1-year follow-up. Our main finding was an increased regulatory T cell response after a 1-year follow-up and its link with clinical improvement in PD patients. In conclusion, after a 1-year follow-up, PD patients exhibited increased levels of regulatory populations, which correlated with clinical improvement. However, a persistent inflammatory environment and active immune response were observed., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
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- 2024
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12. Regulatory impairment in untreated Parkinson's disease is not restricted to Tregs: other regulatory populations are also involved.
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Álvarez-Luquín DD, Arce-Sillas A, Leyva-Hernández J, Sevilla-Reyes E, Boll MC, Montes-Moratilla E, Vivas-Almazán V, Pérez-Correa C, Rodríguez-Ortiz U, Espinoza-Cárdenas R, Fragoso G, Sciutto E, and Adalid-Peralta L
- Subjects
- Aged, Cytokines blood, Female, Humans, Male, Middle Aged, Parkinson Disease immunology, B-Lymphocytes, Regulatory immunology, Dendritic Cells immunology, Parkinson Disease blood, T-Lymphocytes, Regulatory immunology
- Abstract
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Various studies have suggested that the immune response plays a key role in this pathology. While a predominantly pro-inflammatory peripheral immune response has been reported in treated and untreated PD patients, the study of the role of the regulatory immune response has been restricted to regulatory T cells. Other immune suppressive populations have been described recently, but their role in PD is still unknown. This study was designed to analyze the pro and anti-inflammatory immune response in untreated PD patients, with emphasis on the regulatory response., Methods: Thirty-two PD untreated patients and 20 healthy individuals were included in this study. Peripheral regulatory cells (CD4+Tregs, Bregs, CD8+Tregs, and tolerogenic dendritic cells), pro-inflammatory cells (Th1, Th2, and Th17 cells; active dendritic cells), and classical, intermediate, and non-classical monocytes were characterized by flow cytometry. Plasmatic levels of TNF-α, IFN-γ, IL-6, GM-CSF, IL-12p70, IL-4, IL-13, IL-17α, IL-1β, IL-10, TGF-β, and IL-35 were determined by ELISA., Results: Decreased levels of suppressor Tregs, active Tregs, Tr1 cells, IL-10-producer CD8regs, and tolerogenic PD-L1+ dendritic cells were observed. With respect to the pro-inflammatory response, a decrease in IL-17-α and an increase in IL-13 levels were observed., Conclusion: A decrease in the levels of regulatory cell subpopulations in untreated PD patients is reported for the first time in this work. These results suggest that PD patients may exhibit a deficient suppression of the pro-inflammatory response, which could contribute to the pathophysiology of the disease.
- Published
- 2019
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13. [Mycotic anuerysm secondary to bacterial endocarditis. Review apropos of a case].
- Author
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Almazán V, Pulpón A, de Teresa L, Catalán E, Burgui L, and Artaza Andrade M
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- Adult, Aneurysm, Infected drug therapy, Aortic Valve Insufficiency surgery, Endocarditis, Bacterial drug therapy, Female, Humans, Penicillin G therapeutic use, Postoperative Complications drug therapy, Rheumatic Heart Disease surgery, Streptomycin therapeutic use, Aneurysm, Infected etiology, Endocarditis, Bacterial complications, Heart Valve Prosthesis adverse effects, Postoperative Complications etiology
- Abstract
A case is presented of Subacute Bacterial Endocarditis on a biological Duramater Prosthesis. In the evolution curse, the patient presented an intraparenchimal cerebral haemorrhage, where--upon the angiographic studies demonstrated the existence of a mycotic aneurysm in the left median cerebral arterial territory. With specific antibiotic therapy and replacement of the prosthesis, the clinical evolution of the case, was positive, and later angiographies evidenced the disappearance of the aneurysm. The incidence of intracranial mycotic aneurysm complicating bacterial endocarditis is relatively high (up to 4% in post-mortem series). There have been very few cases communicated up to now with angiographic demonstration. Mortality is similar in patients under surgical or medical treatment. The aetipothogenic aspects are discussed, as well as the recommended therapeutic measures.
- Published
- 1978
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