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Your search keyword '"Almeida, Aline Marengoni"' showing total 9 results
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9 results on '"Almeida, Aline Marengoni"'

2. Treating maize plants with benzohydrazide increases saccharification of lignocellulose: A non-transgenic approach to improve cellulosic ethanol production

Author

Martarello, Danielly Caroline Inacio, Tonete-Diniz, Débora Carvalho, Gonzaga, Diego Eduardo Romero, Almeida, Aline Marengoni, Constantin, Renato Polimeni, da Silva, Karla Gabriela, Constantin, Rodrigo Polimeni, Marchiosi, Rogério, Alves-Olher, Vanessa Guimarães, Rios, Fabiano Aparecido, Ferrarese-Filho, Osvaldo, and dos Santos, Wanderley Dantas

Published
2023
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3. Unraveling Shikimate Dehydrogenase Inhibition by 6-Nitroquinazoline-2,4-diol and its Impact on Soybean and Maize Growth

Author

Almeida, Aline Marengoni, primary, Abrahão, Josielle, additional, Seixas, Flavio Augusto Vicente, additional, Bueno, Paulo Sergio Alves, additional, Oliveira, Marco Aurélio Schüler de, additional, Tomazini, Larissa Fonseca, additional, Constantin, Rodrigo Polimeni, additional, dos Santos, Wanderley Dantas, additional, Marchiosi, Rogério, additional, and Ferrarese-Filho, Osvaldo, additional

Published
2024
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5. Unraveling Shikimate Dehydrogenase Inhibition by 6-Nitroquinazoline-2,4-diol and Its Impact on Soybean and Maize Growth.

Author

Almeida, Aline Marengoni, Abrahão, Josielle, Seixas, Flavio Augusto Vicente, Bueno, Paulo Sergio Alves, Oliveira, Marco Aurélio Schüler de, Tomazini, Larissa Fonseca, Constantin, Rodrigo Polimeni, dos Santos, Wanderley Dantas, Marchiosi, Rogério, and Ferrarese-Filho, Osvaldo

Subjects
*HERBICIDES, *GALLIC acid, *ARABIDOPSIS thaliana, *SOYBEAN, *AMINO acids, *CORN, *GLYPHOSATE, *DYNAMIC simulation
Abstract

The shikimate pathway is crucial for the biosynthesis of aromatic amino acids in plants and represents a promising target for developing new herbicides. This work aimed to identify inhibitors of shikimate dehydrogenase (SDH), a key enzyme of the shikimate pathway that catalyzes the conversion of 3-dehydroshikimate to shikimate. Virtual screening and molecular dynamic simulations were performed on the SDH active site of Arabidopsis thaliana (AtSDH), and 6-nitroquinazoline-2,4-diol (NQD) was identified as a potential inhibitor. In vitro assays showed that NQD decreased the activity of AtSDH by reducing Vmax while keeping KM unchanged, indicating non-competitive inhibition. In vivo, hydroponic experiments revealed that NQD reduced the root length of soybean and maize. Additionally, NQD increased the total protein content and certain amino acids. Soybean roots uptake NQD more efficiently than maize roots. Furthermore, NQD reduced shikimate accumulation in glyphosate-treated soybean roots, suggesting its potential to restrict the flow of metabolites along the shikimate pathway in soybean. The simultaneous treatment of maize seedlings with glyphosate and NQD accumulated gallic acid in the roots, indicating that NQD inhibits SDH in vivo. Overall, the data indicate that NQD inhibits SDH both in vitro and in vivo, providing valuable insights into the potential development of herbicides targeting SDH. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Treating maize plants with benzohydrazide increases saccharification of lignocellulose: A non-transgenic approach to improve cellulosic ethanol production

Author

Martarello, Danielly Caroline Inacio, primary, Tonete-Diniz, Débora Carvalho, additional, Gonzaga, Diego Eduardo Romero, additional, Almeida, Aline Marengoni, additional, Constantin, Renato Polimeni, additional, da Silva, Karla Gabriela, additional, Constantin, Rodrigo Polimeni, additional, Marchiosi, Rogério, additional, Alves-Olher, Vanessa Guimarães, additional, Rios, Fabiano Aparecido, additional, Ferrarese-Filho, Osvaldo, additional, and dos Santos, Wanderley Dantas, additional

Published
2021
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9. Estudo de caso

Author

Godoy, Mariane Aparecida Franco de, primary, Almeida, Aline Marengoni, additional, Silva, Karla Gabriela da, additional, Castro, Ana Luiza de Brito Portela, additional, and Carvalho, Luciana Andreia Borin, additional

Published
2018
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