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Sultan M Alshahrani,1 Amjad Alotaibi,2 Ebtesam Almajed,2 Aisha Alotaibi,2 Kholoud Alotaibi,2 Sara Albisher3 1Department of Neurosciences, King Abdullah bin Abdulaziz University Hospital, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; 2College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; 3College of Medicine, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Sultan M Alshahrani, Department of Neurosciences, King Abdullah bin Abdulaziz University Hospital, Princess Nourah Bint Abdulrahman University, Airport Road, Riyadh, 11564, Saudi Arabia, Tel +966-112803212, Fax +966-112800000, Email sumalshahrani@kaauh.edu.saIntroduction: Contracting coronavirus disease (COVID-19) during pregnancy has been linked to an increased risk of severe maternal and fetal complications. Mass vaccination is considered a promising solution to successfully combat the COVID-19 pandemic. It includes vaccinating of pregnant and breastfeeding women. The success of a vaccine is determined not only by its efficacy, but also by its acceptability. Therefore, our study aimed to explore the acceptability and reluctance of pregnant and breastfeeding women to receive COVID-19 vaccination in Saudi Arabia.Methods: This cross-sectional study was conducted in Saudi Arabia from March 2022-beginning to June 2022-end. Using an online self-administered questionnaire with a convenience sampling technique, we assessed women for pregnancy, gravidity, parity, high-risk pregnancy, trimester of pregnancy, and current or planned breastfeeding. Furthermore, we assessed patients with preexisting chronic illnesses. The questionnaire comprised sociodemographic data and items drawn from Goncu Ayhan et al, including vaccination history, perception of risk related to the COVID-19 pandemic, impact of the COVID-19 pandemic, and acceptance and attitude toward future COVID-19 vaccination.Results: A total of 854 women (615 pregnant and 192 breastfeeding women) wer

Nouran A Aleyeidi,1 Raneem S Alqahtani,2 Hawazin F Alotaibi,2 Amjad H Alotaibi,2 Kholoud Mohsen Alotaibi,2 Reenad Mohammed Alnofiey2 1Department of Clinical Sciences, Community Medicine Course, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; 2College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi ArabiaCorrespondence: Nouran A Aleyeidi Tel +966 504304577Email naaleyeidi@pnu.edu.saPurpose: This cross-sectional study aimed to investigate the impact of COVID-19 quarantine on the severity of migraine symptoms and stress among adults in Saudi Arabia.Patients and Methods: Between December 2020 and February 2021, 1212 participants aged 18– 65 years completed an online self-administered questionnaire that covered sociodemographic data, self-administered questions, the ID migraine screener, numeric pain rating scale, and the perceived stress scale. Statistical analyses were performed using SPSS. Student’s t-test, paired t-test, and analysis of variance were used to compare quantitative variables, while the chi-square test was used to compare qualitative variables.Results: After removing ineligible and incomplete responses, we analyzed data obtained from 1111 participants. The mean age of the participants was approximately 29 years old (± 11.2 years); moreover, 87% were females. Headache severity during the COVID-19 quarantine was significantly lower than that during the last 3 months, with a difference of only 0.41 on the 1– 10 pain severity scale. There was a significantly increased stress prevalence during the COVID-19 quarantine. During the COVID-19 quarantine, 49%, 56%, and 62% of patients without migraine, patients with possible migraine, and patients with diagnosed migraine, respectively, reported worsening of their perceived stress. There was a weak positive correlation between the severity of migraine symptoms and stress during COVID-19 quarantine. Moreover, headache severity was positively affec