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5. Interplay between Adamantiades‐Behçet's disease and COVID‐19 – a case series from the German registry of Adamantiades‐Behçet's disease.

Author

Lim, Anthony, Altenburg, Andreas, and Zouboulis, Christos C.

Subjects
*COVID-19, *COUGH, *TASTE disorders, *BEHCET'S disease, *MEDICAL personnel, *IMMUNOLOGIC diseases
Abstract

Only rudimentary data on COVID-19 in ABD patients exist, and there is no information about the optimal management of ABD patients during the pandemic period. COVID-19 results in a multi-faceted inflammatory disease and immune-mediated organ damage. Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 global rheumatology Alliance physician registry: a retrospective cohort study. [Extracted from the article]

Published
2023
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7. Documentation of psoriasis in routine care – expert consensus on a German data set

Author

Otten, Marina, primary, Mrowietz, Ulrich, additional, Kiedrowski, Ralph Michael, additional, Otto, Ramona, additional, Altenburg, Andreas, additional, Aschoff, Roland, additional, Beissert, Stefan, additional, Beiteke, Ulrike, additional, Bonnekoh, Bernd, additional, Hoffmann, Matthias, additional, Körber, Andreas, additional, Maaßen, Dirk, additional, Mössner, Rotraut, additional, Navarini, Alexander, additional, Petering, Holger, additional, Ramaker‐Brunke, Jutta, additional, Rosenbach, Thomas, additional, Schwichtenberg, Uwe, additional, Sticherling, Michael, additional, Sondermann, Wiebke, additional, Thaci, Diamant, additional, Timmel, Andreas, additional, Tsianakas, Athanasios, additional, Werfel, Thomas, additional, Wilsmann‐Theis, Dagmar, additional, and Augustin, Matthias, additional

Published
2021
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8. Dokumentation der Psoriasis in der Routineversorgung – Expertenkonsens zu einem deutschen Datensatz

Author

Otten, Marina, primary, Mrowietz, Ulrich, additional, Kiedrowski, Ralph Michael, additional, Otto, Ramona, additional, Altenburg, Andreas, additional, Aschoff, Roland, additional, Beissert, Stefan, additional, Beiteke, Ulrike, additional, Bonnekoh, Bernd, additional, Hoffmann, Matthias, additional, Körber, Andreas, additional, Maaßen, Dirk, additional, Mössner, Rotraut, additional, Navarini, Alexander, additional, Petering, Holger, additional, Ramaker‐Brunke, Jutta, additional, Rosenbach, Thomas, additional, Schwichtenberg, Uwe, additional, Sticherling, Michael, additional, Sondermann, Wiebke, additional, Thaci, Diamant, additional, Timmel, Andreas, additional, Tsianakas, Athanasios, additional, Werfel, Thomas, additional, Wilsmann‐Theis, Dagmar, additional, and Augustin, Matthias, additional

Published
2021
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11. German S3‐Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm – Part 2: Treatment monitoring and specific clinical or comorbid situations

Author

Nast, Alexander, primary, Altenburg, Andreas, additional, Augustin, Matthias, additional, Boehncke, Wolf‐Henning, additional, Härle, Peter, additional, Klaus, Joachim, additional, Koza, Joachim, additional, Mrowietz, Ulrich, additional, Ockenfels, Hans‐Michael, additional, Philipp, Sandra, additional, Reich, Kristian, additional, Rosenbach, Thomas, additional, Schlaeger, Martin, additional, Schmid‐Ott, Gerhard, additional, Sebastian, Michael, additional, Kiedrowski, Ralph, additional, Weberschock, Tobias, additional, and Dressler, Corinna, additional

Published
2021
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12. Deutsche S3‐Leitlinie zur Therapie der Psoriasis vulgaris, adaptiert von EuroGuiDerm – Teil 2: Therapiemonitoring, besondere klinische Situationen und Komorbidität

Author

Nast, Alexander, primary, Altenburg, Andreas, additional, Augustin, Matthias, additional, Boehncke, Wolf‐Henning, additional, Härle, Peter, additional, Klaus, Joachim, additional, Koza, Joachim, additional, Mrowietz, Ulrich, additional, Ockenfels, Hans‐Michael, additional, Philipp, Sandra, additional, Reich, Kristian, additional, Rosenbach, Thomas, additional, Schlaeger, Martin, additional, Schmid‐Ott, Gerhard, additional, Sebastian, Michael, additional, Kiedrowski, Ralph, additional, Weberschock, Tobias, additional, and Dressler, Corinna, additional

Published
2021
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13. German S3‐Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm – Part 1: Treatment goals and treatment recommendations

Author

Nast, Alexander, primary, Altenburg, Andreas, additional, Augustin, Matthias, additional, Boehncke, Wolf‐Henning, additional, Härle, Peter, additional, Klaus, Joachim, additional, Koza, Joachim, additional, Mrowietz, Ulrich, additional, Ockenfels, Hans‐Michael, additional, Philipp, Sandra, additional, Reich, Kristian, additional, Rosenbach, Thomas, additional, Schlaeger, Martin, additional, Schmid‐Ott, Gerhard, additional, Sebastian, Michael, additional, Kiedrowski, Ralph, additional, Weberschock, Tobias, additional, and Dressler, Corinna, additional

Published
2021
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14. Deutsche S3‐Leitlinie zur Therapie der Psoriasis vulgaris, adaptiert von EuroGuiDerm – Teil 1: Therapieziele und Therapieempfehlungen

Author

Nast, Alexander, primary, Altenburg, Andreas, additional, Augustin, Matthias, additional, Boehncke, Wolf‐Henning, additional, Härle, Peter, additional, Klaus, Joachim, additional, Koza, Joachim, additional, Mrowietz, Ulrich, additional, Ockenfels, Hans‐Michael, additional, Philipp, Sandra, additional, Reich, Kristian, additional, Rosenbach, Thomas, additional, Schlaeger, Martin, additional, Schmid‐Ott, Gerhard, additional, Sebastian, Michael, additional, Kiedrowski, Ralph, additional, Weberschock, Tobias, additional, and Dressler, Corinna, additional

Published
2021
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27. Gender-specific differences in Adamantiades–Behçet’s disease manifestations: an analysis of the German registry and meta-analysis of data from the literature

Author

Bonitsis, Nikolaos G., primary, Luong Nguyen, Liem B., additional, LaValley, Michael P., additional, Papoutsis, Nestor, additional, Altenburg, Andreas, additional, Kötter, Ina, additional, Micheli, Christiana, additional, Maldini, Carla, additional, Mahr, Alfred, additional, and Zouboulis, Christos C., additional

Published
2014
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32. Behandlung chronisch-rezidivierender oraler Aphthen.

Author

Altenburg, Andreas, El-Haj, Nadine, Micheli, Christiana, Puttkammer, Marion, Abdel-Naser, Mohammed Badawy, and Zouboulis, Christos C.

Abstract

Copyright of Deutsches Ärzteblatt International is the property of Deutscher Aerzte-Verlag GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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35. Longterm Visual Prognosis of Patients with Ocular Adamantiades-Behçet's Disease Treated with Interferon-α-2a

Author

Krause, Lothar, Altenburg, Andreas, Pleyer, Uwe, Köhler, Anne-Katrin, Zouboulis, Christos, and Foerster, Michael

Abstract

OBJECTIVE: Relapsing ocular involvement is one of the major manifestations in Adamantiades-Behçet's disease (ABD). Combining systemic corticosteroids with cyclosporin A is currently the treatment of choice. Interferon-α (IFN-α) has proven to be effective in mucocutaneous ABD and has been reported to improve ocular lesions. We examined the longterm effects of IFN-α-2a in a case series of 45 patients with ocular involvement. METHODS: Since 1988, 45 patients (79 eyes of 90 eyes) with ocular involvement in ABD have been treated with IFN-α (3 × 6-9 Mio IU per wk). In the initial acute phase of the disease, patients additionally received short-term corticosteroids (oral prednisolone 100 mg/day), tapered to a maintenance dose of 10 mg/day within 2 weeks. IFN-α-2a was administered as longterm therapy with a mean duration of 30 months (range 1.1-101 mo). RESULTS: IFN-α-2a/prednisolone treatment was effective against vasculitis, optic nerve neuropathy, and iritis. Sixty-four eyes had no recurrence under therapy. To date, recurrences have been seen in 26 eyes under IFN-α treatment. Flu-like symptoms were recorded in nearly all patients (n = 43). Further side effects were dose-dependent reversible thrombocytopenia (n = 1), psychosis (n = 3), depression (n = 13), thyroiditis (n = 1), and reversible diffuse alopecia (n = 7). In our series, 92% of all eyes showed stable or improved visual acuity in longterm followup. CONCLUSION: Longterm remission of ocular inflammation can be achieved with the combination of IFN-α and low-dose corticosteroids.

Published
2008

36. Schistosomiasis (bilharziasis) and male infertility.

Author

Abdel‐Naser, Mohamed Badawy, Altenburg, Andreas, Zouboulis, Christos C., and Wollina, Uwe

Abstract

Schistosomiasis (bilharziasis) is an endemic parasitic disease of a major source of morbidity and mortality for developing countries. It is caused by different species of blood flukes (trematode worms) of the genus Schistosoma, the most important of which are S. haematobium which infests the genitourinary tract and S. mansoni and S. japonicum which infest the gastrointestinal tract. The incidence of schistosome‐induced male infertility is not known and probably underestimated being overshadowed by the more severe and often fatal urinary and gastrointestinal complications. Several causes may contribute to schistosomiasis‐induced male infertility, such as hormonal imbalance, testicular tissue damage and genital ductal system obstruction, in addition to decreased libido and erectile dysfunction due to associated hormonal imbalance and prostatic infestation. Demonstration of the schistosome ova in seminal plasma or testicular tissue confirms the diagnosis. Treatment of schistosomiasis‐induced male infertility depends on clinical evaluation and includes, besides anthelmintic treatment, hormonal replacement and assisted reproduction (IVF/ICSI) in cases of severe oligozoospermia and or obstructive and nonobstructive azoospermia. [ABSTRACT FROM AUTHOR]

Published
2019
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38. Documentation of psoriasis in routine care - expert consensus on a German data set.

Author

Otten M, Mrowietz U, von Kiedrowski RM, Otto R, Altenburg A, Aschoff R, Beissert S, Beiteke U, Bonnekoh B, Hoffmann M, Körber A, Maaßen D, Mössner R, Navarini A, Petering H, Ramaker-Brunke J, Rosenbach T, Schwichtenberg U, Sticherling M, Sondermann W, Thaci D, Timmel A, Tsianakas A, Werfel T, Wilsmann-Theis D, and Augustin M

Subjects
Consensus, Delphi Technique, Documentation, Germany, Humans, Psoriasis diagnosis, Psoriasis epidemiology, Psoriasis therapy
Abstract

Background and Objectives: Documenting patient data in psoriasis clinical practice can improve care, but standardized and transparent documentation is rare. The current project aimed to develop a data set for the documentation of psoriasis in daily practice., Material and Methods: In four online Delphi rounds and one in-person meeting, 27 psoriasis experts allocated variables to a standard, an optimal and an optional data set. Most of the questions were standardized. Open questions were included to allow for the provision of reasons and to enlarge the data sets. Furthermore, in the in-person meeting we considered a) patients' attitudes and b) dermatologists' information on the current usage and acceptability in Germany., Results: The consensus approach resulted in a data set with 69 variables. The standard data set includes 20, the optimal data set 31 and the optional data set 18 variables. In summary, the data set can mainly be grouped into master data, general status and medical history data, medical history of psoriasis, status of psoriasis, diagnostics and comorbidity, therapies and patient-reported outcomes., Conclusions: The consensus recommendation of a standard, an optimal and an optional data set for routine care of psoriasis intends to be a decision-making aid and an orientation for both daily practice and further development of documentation systems., (© 2021 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.)

Published
2021
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39. German S3-Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm - Part 2: Treatment monitoring and specific clinical or comorbid situations.

Author

Nast A, Altenburg A, Augustin M, Boehncke WH, Härle P, Klaus J, Koza J, Mrowietz U, Ockenfels HM, Philipp S, Reich K, Rosenbach T, Schlaeger M, Schmid-Ott G, Sebastian M, von Kiedrowski R, Weberschock T, and Dressler C

Subjects
Adaptation, Physiological, Germany epidemiology, Humans, Psoriasis diagnosis, Psoriasis epidemiology, Psoriasis therapy
Published
2021
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42. German S3-Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm - Part 1: Treatment goals and treatment recommendations.

Author

Nast A, Altenburg A, Augustin M, Boehncke WH, Härle P, Klaus J, Koza J, Mrowietz U, Ockenfels HM, Philipp S, Reich K, Rosenbach T, Schlaeger M, Schmid-Ott G, Sebastian M, von Kiedrowski R, Weberschock T, and Dressler C

Subjects
Adaptation, Physiological, Germany, Humans, Goals, Psoriasis diagnosis, Psoriasis therapy
Published
2021
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43. [Enlarged mediastinal lymph nodes of a patient with malignant melanoma stage IV under pembrolizumab treatment].

Author

Nikolakis G, Brunner M, Boye H, Arndt N, Altenburg A, Vaiopoulos A, and Zouboulis CC

Subjects
Adult, Humans, Lymph Nodes, Lymphadenopathy chemically induced, Melanoma pathology, Treatment Outcome, Antibodies, Monoclonal, Humanized therapeutic use, Lymphadenopathy drug therapy, Melanoma drug therapy, Pulse Therapy, Drug methods, Steroids therapeutic use
Abstract

A 40-year-old patient with malignant melanoma pT4bN0M1a stage IV (AJCC classification 2017) was treated with the PD-1/PD-L1 antibody pembrolizumab. Three months after treatment initiation the patient developed enlarged mediastinal lymph nodes despite the partial response of the cutaneous metastases. An elective lymph node extirpation was performed. The histopathological result was consistent with a sarcoid-like reaction. Treatment was discontinued and a pulse therapy with systemic steroids led to a significant remission of the lymphadenopathy. This side effect can manifest both during PD-1/PD-L1 antibody and CTLA-4 antibody therapy and should be included in the differential diagnosis of mediastinal lymphadenopathy.

Published
2019
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44. Reactive hyperplasias,precancerous and malignant lesions of the oral mucosa.

Author

Krahl D, Altenburg A, and Zouboulis CC

Subjects
Humans, Mouth Diseases, Practice Guidelines as Topic, Practice Patterns, Physicians', Mouth Mucosa pathology, Mouth Neoplasms diagnosis, Mouth Neoplasms therapy, Precancerous Conditions diagnosis, Precancerous Conditions therapy, Pseudolymphoma diagnosis, Pseudolymphoma therapy
Abstract

The oral cavity contains many organs and tissues compressed in a small area. Accordingly oral tumors have a wide variety of appearances. Reactive hyper-plastic lesions include epulis,morsicatio,traumatic ulcer or palatal hyperplasia. These benign lesions must be separated clinically and histologically from precancerous and neoplastic lesions. In leukoplakia,the individual risk can be estimated by clinical signs. Nevertheless histopathology is mandatory because precancerous lesions usually precede or accompany most oral cancers. Amalgam tattoo,oral nevi and melanoacanthoma have to be considered as differential diagnoses of oral melanoma. Accurate clinico-pathological diagnosis is mandatory to insure appropriate therapy. Oral soft tissue tumors such as Kaposi sarcoma and multiple mucosal neuromas in MEN 2b require interdisciplinary management. Diseases affecting the minor salivary glands which may be encountered by dermatologists include mucocele, necrotizing sialometa-plasia,and tumors such as pleomorphic adenoma.

Published
2008
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