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1. Mortality risk factors among critically ill children with MIS-C in PICUs: a multicenter study

Author

Sık, Guntulu, Inamlık, Aysegul, Akçay, Nihal, Kesici, Selman, Aygun, Fatih, Kendırlı, Tanıl, Atay, Gurkan, Sandal, Ozlem, Varol, Fatih, Ozkaya, Pınar Yazıcı, Duyu, Muhterem, Bırbılen, Ahmet Ziya, Ozcan, Serhan, Arslan, Gazi, Kangın, Murat, Bayraktar, Suleyman, Altug, Umit, Anıl, Ayşe Berna, Havan, Merve, Yetımakman, Ayse Filiz, Dalkıran, Tahir, Zengın, Neslihan, Oto, Arzu, Kıhtır, Hasan Serdar, Gırgın, Feyza İnceköy, Telhan, Leyla, Yıldızdas, Dincer, Yener, Nazik, Yukselmıs, Ufuk, Alakaya, Mehmet, Kılınc, Mehmet Arda, Celegen, Mehmet, Dursun, Adem, Battal, Fatih, Sarı, Ferhat, Ozkale, Murat, Topal, Sevgi, Kocaoglu, Celebi, Yazar, Abdullah, Alacakır, Nuri, Odek, Caglar, Yaman, Ayhan, and Cıtak, Agop

Published
2023
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2. Mortality risk factors among critically ill children with MIS-C in PICUs: a multicenter study

Author

Celegen, Mehmet, Kılınc, Mehmet Arda, Alakaya, Mehmet, Yukselmıs, Ufuk, Yener, Nazik, Yıldızdas, Dincer, Telhan, Leyla, Gırgın, Feyza İnceköy, Kıhtır, Hasan Serdar, Oto, Arzu, Zengın, Neslihan, Dalkıran, Tahir, Yetımakman, Ayse Filiz, Havan, Merve, Duman, Murat, Altug, Umit, Bayraktar, Suleyman, Kangın, Murat, Arslan, Gazi, Ozcan, Serhan, Bırbılen, Ahmet Ziya, Duyu, Muhterem, Ozkaya, Pınar Yazıcı, Varol, Fatih, Sandal, Ozlem, Atay, Gurkan, KENDİRLİ, TANIL, AYGÜN, FATİH, KESİCİ, SELMAN, Akçay, Nihal, Inamlık, Aysegul, Sık, Guntulu, Başar, Evic Zeynep, Mercan, Mehmet, Bal, Alkan, Kılıc, Nevin, Ongun, Ebru Atike, Ozturk, Makbule Nilufer, Ekıncı, Faruk, Udurgucu, Muhammed, Arslankoylu, Ali Ertug, Kutlu, Nurettin Onur, Bukulmez, Aysegul, Özsoylu, Serkan, Anıl, Ayşe Berna, Ozdemır, Göktug, Emeksız, Serhat, Durak, Fatih, Boyraz, Merve, Arı, Hatice Feray, Sahın, Ebru, Seven, Pınar, Erdogan, Seher, Gun, Emrah, Durak, Cansu, Katlan, Banu, Sevketoglu, Esra, Annayev, Agageldi, Bıngol, Ibrahim, Cıtak, Agop, Yaman, Ayhan, Odek, Caglar, Alacakır, Nuri, Yazar, Abdullah, Kocaoglu, Celebi, Topal, Sevgi, Ozkale, Murat, Sarı, Ferhat, Battal, Fatih, Dursun, Adem, Celık, Taylan, Ozkale, Yasemin, Kılıc, Ahmet Osman, Harmanogulları, Sezer, Luleyap, Doga, Yener, Gülcin Otar, Talay, Mehmet Nur, and Sık G., Inamlık A., Akçay N., KESİCİ S., AYGÜN F., KENDİRLİ T., Atay G., Sandal O., Varol F., Ozkaya P. Y., et al.

Subjects
Internal Medicine Sciences, Klinik Tıp, Dahili Tıp Bilimleri, CLINICAL MEDICINE, Sağlık Bilimleri, Clinical Medicine (MED), Tıp, Çocuk Sağlığı ve Hastalıkları, Child Health and Diseases, PEDIATRICS, Health Sciences, Pediatrics, Perinatology and Child Health, Medicine, Klinik Tıp (MED), PEDİATRİ, Pediatri, Perinatoloji ve Çocuk Sağlığı
Abstract

Background: This study evaluated of clinical characteristics, outcomes, and mortality risk factors of a severe multisystem inflammatory syndrome in children admitted to a the pediatric intensive care unit. Methods: A retrospective multicenter cohort study was conducted between March 2020 and April 2021 at 41 PICUs in Turkey. The study population comprised 322 children diagnosed with multisystem inflammatory syndrome. Results: The organ systems most commonly involved were the cardiovascular and hematological systems. Intravenous immunoglobulin was used in 294 (91.3%) patients and corticosteroids in 266 (82.6%). Seventy-five (23.3%) children received therapeutic plasma exchange treatment. Patients with a longer duration of the PICU stay had more frequent respiratory, hematological, or renal involvement, and also had higher D-dimer, CK-MB, and procalcitonin levels. A total of 16 patients died, with mortality higher in patients with renal, respiratory, or neurological involvement, with severe cardiac impairment or shock. The non-surviving group also had higher leukocyte counts, lactate and ferritin levels, and a need for mechanical ventilation. Conclusions: In cases of MIS-C, high levels of D-dimer and CK-MB are associated with a longer duration of PICU stay. Non-survival correlates with elevated leukocyte counts and lactate and ferritin levels. We were unable to show any positive effect of therapeutic plasma exchange therapy on mortality. Impact: MIS-C is a life-threatening condition.Patients need to be followed up in the intensive care unit.Early detection of factors associated with mortality can improve outcomes.Determining the factors associated with mortality and length of stay will help clinicians in patient management.High D-dimer and CK-MB levels were associated with longer PICU stay, and higher leukocyte counts, ferritin and lactate levels, and mechanical ventilation were associated with mortality in MIS-C patients.We were unable to show any positive effect of therapeutic plasma exchange therapy on mortality.

Published
2023

3. Increased Severe Cases and New-Onset Type 1 Diabetes Among Children Presenting With Diabetic Ketoacidosis During First Year of COVID-19 Pandemic in Turkey

Author

Kiral, Eylem, primary, Kirel, Birgul, additional, Havan, Merve, additional, Keskin, Mehmet, additional, Karaoglan, Murat, additional, Yildirim, Ahmet, additional, Kangin, Murat, additional, Talay, Mehmet Nur, additional, Urun, Tuba, additional, Altug, Umit, additional, Kesici, Selman, additional, Tufan, Erennur, additional, Kacmaz, Ebru, additional, Bozan, Gurkan, additional, Azapagasi, Ebru, additional, Uysal Yazici, Mutlu, additional, Ozturk, Zeynelabidin, additional, Yesilbas, Osman, additional, Karaguzel, Gulay, additional, Kaya, Gulay, additional, Barlas, Ulkem, additional, Duyu, Muhterem, additional, Boyraz, Merve, additional, Sevketoglu, Esra, additional, Akcay, Nihal, additional, Hancili, Suna, additional, Guven, Ayla, additional, Dursun, Oǧuz, additional, Ulgen Tekerek, Nazan, additional, Ozcifci, Gokçen, additional, Yazici, Pinar, additional, Turanli, Eda, additional, Kendirli, Tanil, additional, Kahveci, Fevzi, additional, Yetimakman, Ayse Filiz, additional, Citak, Agop, additional, Şik, Guntulu, additional, Bingol, Ibrahim, additional, Aygun, Fatih, additional, Durak, Cansu, additional, Yilmaz, Resul, additional, Bugrul, Fuat, additional, Sari, Yusuf, additional, Tekguç, Hakan, additional, Albayrak, Hatice, additional, Yener, Nazik, additional, Agin, Hasan, additional, Soydan, Ekin, additional, Yildizdas, Dincer, additional, Dilek, Semine Ozdemir, additional, Yalindag, Nilufer, additional, Incekoy-Girgin, Feyza, additional, Alacakir, Nuri, additional, Tutunculer, Filiz, additional, Arslanaoglu, Mehmet Ozgur, additional, Aydin, Can, additional, Bilgin, Muzaffer, additional, Simsek, Enver, additional, and Dinleyici, Ener Cagri, additional

Published
2022
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7. Toplumumuzda Okuma Alışkanlığı ve Medya Takibini Etkileyen Faktörler.

Author

Bülbül, Selda Hızel, Misirlioglu, Emine Dibek, Ceyhun, Gulsen, Araz, Nilgun Col, and Altug, Umit

Subjects
*READING, *SCHOOL children, *PRIMARY school teachers, *MEDICAL students, *VIDEO games, *ECONOMIC status, *GRADUATES
Abstract

AIM: Reading habit in our country is quite below the world standards. In this study, the aim was to investigate reading habit, and media follow-up of Turkey in three distinct provinces. METHOD: The research group of this cross-sectional study was composed of stuff and students of medical schools, teachers and parents of the students of primary schools in three provinces. Data were obtained from questionnaires self-filled by 750 people. RESULTS: Of the people whose ages ranged from 16 to 65 (31.75±10.19) years, 28.7% were students, 14.1% were house-wives, and 7.9% were lecturers. They spent their leisure time mostly by watching TV (25.6%), playing video/internet games (9.9%), reading books (7.9%), and merely going to cinema/theater (16.7%). Of the group, 41.7% read ⩽5 books per year, whereas 10.7% read no books at all. The reasons for not reading were lack of time (66.5%) and economical (10.8%). While 61.4% of those with very good economic status read >6 books per year, this rate was 22.2% among those with poor economic status, and the difference was significant (p=0.000). 32.4% were reading and 30.8% bought newspapers everyday. While 10.5% of primary school graduates bought newspapers every day, this rate was 48.9% among graduates of a university or a master degree (p=0.000). Seven percent of those with very good economic status bought no newspapers, whereas this rate was 43.1% among those with poor economic status (p=0.000). Of the people, 95.3% had a television at home. The most watched programs were the series (34.5%), and news programs (35.7%), respectively. 16.6% of the group did not listen to radio at all and the rest were listening only while driving or doing housework. CONCLUSION: Our study is important in terms of covering people from different sections of Turkish society and emphasizing the low reading habit and media follow-up once more. [ABSTRACT FROM AUTHOR]

Published
2014
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