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2. Percutaneous interventions in Fontan circulation

Author

Marschall, A, primary, Alvarez-Fuente, M, additional, Garrido-Lestache, E, additional, Tellez, L, additional, Sanchez, I, additional, Toledano, M, additional, Molina, I, additional, Rivero, N, additional, Garcia-Ormazabal, I, additional, Tamariz, R, additional, and Del Cerro, M J, additional

Published
2022
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3. The patient with Down syndrome and pulmonary arterial hypertension associated with congenital heart disease: from childhood to adulthood

Author

Playan Escribano, J, primary, Garrido-Lestache, E, additional, Luna, R, additional, Alvarez Fuente, M, additional, Lopez-Meseguer, M, additional, Guillen Rodriguez, I, additional, Perez Penate, G M, additional, Sabate Rotes, A, additional, Elias Hernandez, T, additional, Lopez Ramon, M, additional, Rueda Soriano, J, additional, Perin, F, additional, Blanco, I, additional, Del Cerro Marin, M J, additional, and Escribano Subias, P, additional

Published
2022
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4. Eisenmenger syndrome: is it the same entity in adulthood and pediatric age?

Author

Playan Escribano, J, primary, Garrido-Lestache, E, additional, Cristo Ropero, M J, additional, Alvarez Fuente, M, additional, Barbera, J A, additional, Moreno Galdo, A, additional, Rueda Soriano, J, additional, Rodriguez Ogando, A, additional, Elias Hernandez, T, additional, Guillen Rodriguez, I, additional, Lazaro Salvador, M, additional, Lozano Balseiro, M, additional, Lara Padron, A, additional, Escribano Subias, P, additional, and Del Cerro Marin, M J, additional

Published
2021
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6. National consensus on the cardiological treatment and follow-up of Kawasaki disease

Author

Sombrero, HR, Fernandez-Cooke, E, Sanchez-Manubens, J, Picarzo, JPL, de la Torre, LA, Alvarez-Fuente, M, Garcia, GG, Gutierrez-Larraya, F, Vazquez, BT, McMullan, PD, Perez, GA, Arboledas, FJA, Martin, CA, Echauri, JA, Garcia, PA, Arevalo, P, Rofes, AA, Sanchez, MA, Domingo, EJB, Rodrigo, AB, Abbona, MSB, Fernandez, IB, Tascon, AB, Torralva, CMB, Jover, EB, Rodriguez, CB, Trigo, SB, Sayago, MJB, Diaz, MJC, Tejedor, MTC, Moreno, JIC, Blesa, CC, Bellon, JMC, Cassanello, MP, Malfaz, FC, Spoturno, ACC, Hernandez, RC, Orvay, JAC, Marcos, DC, Manotas, HAC, Peiro, VC, de Caro, AP, Cancho, MD, Iglesias, LAD, Bronte, LD, Menendez, BD, Megias, LD, Tomas, JJD, Colina, PD, Garcia, OD, Garrido, MND, Manzano, PD, Bedoya, JD, Espinosa, JE, Nava, FEE, Pinela, HDE, Asenjo, ME, Ruiz, APF, Aracama, JF, Sarabia, JF, Soria, MTF, Suarez, NF, Belda, AF, Villar, SF, Garcia, JF, Moure, AF, de Vinuesa, APGG, Arzoz, MG, Angleu, FG, Cerro, EG, Rodriguez-Monte, MEGL, Villanueva, NG, Crespo, MG, Carrasco, MEG, Marin, MAG, Menchen, CG, Ipina, FG, Rodriguez, IG, Esteve, MTG, Gomez, MH, Blanco, AH, Sanchez, YH, del Rey, CH, Fernandez, AI, Martin, GI, Fos, II, Riezu, MAI, Casso, MSJ, Montanes, LJ, de Lera, CL, Navarro, LL, Abel, BL, Balseiro, ML, Gonzalez, JL, Julian, NM, Cazcarra, JAM, Toral, MJM, Linero, AM, Garcia, BM, Llagaria, MM, Alonso, SM, Blanch, CM, de Lara, IM, del Villar, MM, Lorente, MIM, Oloron, PM, Soto, MIM, Checa, LM, Morillo, MAM, Lopez, CM, Abad, PM, Ortiz, FM, Gutierrez, AM, Tirado, AM, Montes, AO, Matamala, AO, Garrido, AO, Erroz, IO, Argueta, JRP, Aguera, LP, Molina, EP, Salas, JEP, Carrillo, CJP, Campos, DP, Herrera, VP, Agapito, MAPM, Munuzuri, AP, Pardo, AMP, Roldan, JMP, Picarzo, FJPL, Moreno, MRPP, Perin, F, Fuentes, IP, Izquierdo, BP, Morales, MP, Dalmau, MAP, Ovalle, EP, Poveda, MTR, Rodriguez, SR, Garcia, SMR, Arcelus, ER, Mendez, BR, Armada, AR, Jimenez, NR, Gonzalez, MR, Mesa, MDR, Serrano, RR, Sombrero, MHR, Barba, VR, Ibarra, CR, Vivas, FR, Nunez, FR, Soriano, JR, Rotes, AS, Salguero, FJS, Capunay, JFS, Peracaula, CS, Andres, AS, Calderon, AS, Vaquerizo, CS, Pascual, ES, Robles, MIS, Sanchez-Manjavacas, AS, Baladron, AS, Garcia, RS, Belmonte, DS, Garcia, MS, Cabrera, PS, Moreno, ATM, Moreno, RTM, Hernandez, MAT, Rico, MT, Prat, SU, Carrasco, AIU, Padrino, EV, Adan, MTV, Albert, SV, Nogales, JV, Walter, CC, Martin, MY, Casajona, MDZ, and SECPCC

Subjects
Vasculitis, Arteritis, Consensus, Kawasaki disease, Coronary vessels, intravenous, Mucocutaneous lymphnode syndrome, Immunoglobulins, Coronary aneurysm, Steroids, Aneurysm
Abstract

Kawasaki disease is a self-limiting acute vasculitis that affects small and medium-sized vessels, and is the most common cause of acquired heart disease in children in our environment. Up to 25% of untreated patients develop coronary aneurysms. It is suspected that an infectious agent may be the trigger of the disease, but the causative agent is still unknown. Based on the previous evidence, recommendations are proposed for the diagnosis, treatment of acute disease, and the long-term management of these patients, in order to unify criteria. The diagnosis must be quick, based on easy-to-use algorithms and with the support of complementary tests. This document includes the indication of available imaging techniques, as well as the planning of cardiological examinations based on the initial involvement. Intravenous immunoglobulin is the basis of the initial treatment. The role of corticosteroids is still controversial, but there are studies that support its use as adjuvant treatment. A multidisciplinary working group has developed a scheme with different treatment guidelines depending on the risk factors at diagnosis, the patient's clinical situation, and response to previous treatment, including indications for thromboprophylaxis in patients with coronary involvement. The stratification of risk for long-term treatment is essential, as well as the recommendations on the procedures based on the initial cardiological involvement and its progression. Patients with coronary aneurysms require continuous and uninterrupted cardiological monitoring for life. (C) 2018 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U.

Published
2018

8. Timing of Pulmonary Valve Replacement: How Much Can the Right Ventricle Dilate Before it Looses Its Remodeling Potential?

Author

Alvarez-Fuente, M., primary, Garrido-Lestache, E., additional, Fernandez-Pineda, L., additional, Romera, B., additional, Sánchez, I., additional, Centella, T., additional, Abelleira, C., additional, Villagrá, S., additional, Tamariz, R., additional, Barrios, E., additional, Lamas, M. J., additional, Gomez, R., additional, and Del Cerro, M. J., additional

Published
2015
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9. Poster Session: Right ventricular systolic function

Author

Altman, M., primary, Bergerot, C., additional, Thibault, H., additional, Aussoleil, A., additional, Skuldadt Davidsen, E., additional, Barthelet, M., additional, Derumeaux, G. A., additional, Grapsa, J., additional, Zimbarra Cabrita, I., additional, Afilalo, J., additional, Paschou, S., additional, Dawson, D., additional, Durighel, G., additional, O'regan, D., additional, Howard, L., additional, Gibbs, J., additional, Nihoyannopoulos, P., additional, Morenate Navio, M., additional, Mesa Rubio, M., additional, Ortega, M. D., additional, Ruiz Ortiz, M., additional, Castillo Bernal, F., additional, Del Pino, C. L., additional, Toledano, F., additional, Alvarez-Ossorio, M. P., additional, Ojeda Pineda, S., additional, Lezo Cruz-Conde, J. S. D., additional, Jasaityte, R., additional, Claus, P., additional, Teske, A., additional, Herbots, L., additional, Verheyden, B., additional, Rademakers, F., additional, D'hooge, J., additional, Tocchetti, C. G., additional, Coppola, C., additional, Rea, D., additional, Quintavalle, C., additional, Guarino, L., additional, Castaldo, N., additional, De Lorenzo, C., additional, Condorelli, G., additional, Arra, C., additional, Maurea, N., additional, Voilliot, D., additional, Huttin, O., additional, Camara, Y., additional, Djaballah, W., additional, Carillo, S., additional, Zinzius, P., additional, Sellal, J., additional, Angioi, M., additional, Juilliere, Y., additional, Selton-Suty, C., additional, Dobrowolski, P., additional, Klisiewicz, A., additional, Florczak, E., additional, Prejbisz, A., additional, Szwench, E., additional, Rybicka, J., additional, Januszewicz, A., additional, Hoffman, P., additional, Jurado Roman, A., additional, De Dios Perez, S., additional, De Nicolas, J. M. M., additional, Diaz Anton, B., additional, Rubio Alonso, B., additional, Martin Asenjo, R., additional, Mayordomo Gomez, S., additional, Villagraz Tecedor, L., additional, Blazquez, L., additional, De Meneses, R. T., additional, Bernard, A., additional, Hernandez, A. I., additional, Reynaud, A., additional, Lerclercq, C., additional, Daubert, J., additional, Donal, E., additional, Arjan Singh, R., additional, Sivarani, S., additional, Lim, S., additional, Azman, W., additional, Almeida, M., additional, Cardim, N., additional, Fonseca, V., additional, Carmelo, V., additional, Santos, S., additional, Santos, T., additional, Toste, J., additional, Kosmala, W., additional, Orda, A., additional, Karolko, B., additional, Mysiak, A., additional, Przewlocka-Kosmala, M., additional, Farsalinos, K., additional, Tsiapras, D., additional, Kyrzopoulos, S., additional, Avramidou, E., additional, Vassilopoulou, D., additional, Voudris, V., additional, Hayrapetyan, H., additional, Adamyan, K., additional, Montero Cabezas, J., additional, Granda Nistal, C., additional, Garcia Aranda, B., additional, Sanchez Sanchez, V., additional, Sestito, A., additional, Lamendola, P., additional, Di Franco, A., additional, Lauria, C., additional, Lanza, G., additional, Kukucka, M., additional, Unbehaun, A., additional, Buz, S., additional, Mladenow, A., additional, Kuppe, H., additional, Pasic, M., additional, Habazettl, H., additional, Gemma, D., additional, Montoro Lopez, N., additional, De Celix, M. G. R., additional, Lopez Fernandez, T., additional, De Torres Alba, F., additional, Del Valle, D. I., additional, Ramirez, U., additional, Mesa, J., additional, Moreno Yanguela, M., additional, Lopez Sendon, J., additional, Eveborn, G. W., additional, Schirmer, H., additional, Lunde, P., additional, Heggelund, G., additional, Rasmussen, K., additional, Wang, Z., additional, Lasota, B., additional, Mizia-Stec, K., additional, Mizia, M., additional, Chmiel, A., additional, Adamczyk, T., additional, Chudek, J., additional, Gasior, Z., additional, Venkatesh, A., additional, Johnson, J., additional, Sahlen, A., additional, Brodin, L., additional, Winter, R., additional, Shahgaldi, K., additional, Manouras, A., additional, Valbuena, S., additional, Iniesta, A., additional, Lopez, T., additional, De Torres, F., additional, Salinas, P., additional, Garcia, S., additional, Moreno, M., additional, Lopez-Sendon, J., additional, Lebid, I., additional, Kobets, T., additional, Kuzmenko, T., additional, Katsanos, S., additional, Yiu, K., additional, Clavel, M., additional, Nina Ajmone, N., additional, Van Der Kley, F., additional, Rodes Cabau, J., additional, Schalij, M., additional, Bax, J., additional, Pibarot, P., additional, Delgado, V., additional, Fusini, L., additional, Tamborini, G., additional, Muratori, M., additional, Gripari, P., additional, Marsan, N., additional, Cefalu', C., additional, Ewe, S., additional, Maffessanti, F., additional, Pepi, M., additional, Hasselberg, N., additional, Haugaa, K., additional, Petri, H., additional, Berge, K., additional, Leren, T., additional, Bundgaard, H., additional, Edvardsen, T., additional, Ancona, R., additional, Comenale Pinto, S., additional, Caso, P., additional, Coppola, M., additional, Rapisarda, O., additional, Cavallaro, C., additional, Vecchione, F., additional, D'onofrio, A., additional, Calabro', R., additional, Rimbas, R., additional, Mihaila, S., additional, Enescu, O., additional, Patrascu, N., additional, Dragoi, R., additional, Rimbas, M., additional, Pop, C., additional, Vinereanu, D., additional, Gustafsson, S., additional, Morner, S., additional, Gronlund, C., additional, Suhr, O., additional, Lindqvist, P., additional, Di Bella, G., additional, Zito, C., additional, Minutoli, F., additional, Madaffari, A., additional, Cusma Piccione, M., additional, Mazzeo, A., additional, Massimo, R., additional, Pasquale, M., additional, Vita, G., additional, Carerj, S., additional, Rangel, I., additional, Goncalves, A., additional, Sousa, C., additional, Correia, A., additional, Martins, E., additional, Silva-Cardoso, J., additional, Macedo, F., additional, Maciel, M., additional, Pfeiffer, B., additional, Rigopoulos, A., additional, Seggewiss, H., additional, Alvarez Fuente, M., additional, Sainz Costa, T., additional, Medrano, C., additional, Navarro, M., additional, Blazquez Gamero, D., additional, Ramos, J., additional, Mellado, M., additional, De Jose, M., additional, Munoz, M., additional, Maroto, E., additional, Gargani, L., additional, Gosciniak, P., additional, Pratali, L., additional, Agoston, G., additional, Bruni, C., additional, Guiducci, S., additional, Matucci Cerinic, M., additional, Varga, A., additional, Sicari, R., additional, Picano, E., additional, Zhao, C., additional, Mei, M., additional, Yeung, C., additional, Siu, C., additional, Tse, H., additional, Florescu, M., additional, Magda, L., additional, Mincu, R., additional, Daha, I., additional, Stanescu, C. M., additional, Chirila, L., additional, Baicus, C., additional, Vlase, A., additional, Dan, G., additional, Montoro Lopez, M., additional, Florez Gomez, R., additional, Alonso Ladreda, A., additional, Itziar Soto, C., additional, Rios Blanco, J., additional, Guzman Martinez, G., additional, Lichodziejewska, B., additional, Kurnicka, K., additional, Goliszek, S., additional, Kostrubiec, M., additional, Dzikowska-Diduch, O., additional, Ciurzynski, M., additional, Labyk, A., additional, Krupa, M., additional, Palczewski, P., additional, Pruszczyk, P., additional, De Sousa, C. C., additional, Vigario, A., additional, Pinho, T., additional, Silva Cardoso, J., additional, Park, S.-J., additional, Song, J.-E., additional, Lee, Y.-J., additional, Ha, M.-R., additional, Chang, S.-A., additional, Choi, J.-O., additional, Lee, S.-C., additional, Park, S., additional, Oh, J., additional, Van De Bruaene, A., additional, De Meester, P., additional, Buys, R., additional, Vanhees, L., additional, Delcroix, M., additional, Voigt, J., additional, Budts, W., additional, Blundo, A., additional, Buccheri, S., additional, Monte, I. P., additional, Leggio, S., additional, Tamburino, C., additional, Sotaquira, M., additional, Lang, R., additional, Caiani, E., additional, Floria, M., additional, De Roy, L., additional, Xhaet, O., additional, Blommaert, D., additional, Jamart, J., additional, Gerard, M., additional, Deceuninck, O., additional, Marchandise, B., additional, Seldrum, S., additional, Schroeder, E., additional, Unsworth, B., additional, Sohaib, S., additional, Kulwant-Kaur, K., additional, Malcolme-Lawes, L., additional, Kanagaratnam, P., additional, Malik, I., additional, Ren, B., additional, Mulder, H., additional, Haak, A., additional, Van Stralen, M., additional, Szili-Torok, T., additional, Pluim, J., additional, Geleijnse, M., additional, Bosch, J., additional, Baglini, R., additional, Amaducci, A., additional, D'ancona, G., additional, Van Den Oord, S., additional, Akkus, Z., additional, Ten Kate, G., additional, Renaud, G., additional, Sijbrands, E., additional, De Jong, N., additional, Van Der Lugt, A., additional, Van Der Steen, A., additional, Schinkel, A., additional, Bjallmark, A., additional, Larsson, M., additional, Grishenkov, D., additional, Brodin, L.-A., additional, Brismar, T., additional, Paradossi, G., additional, Sveen, K. A., additional, Nerdrum, T., additional, Hanssen, K., additional, Dahl-Jorgensen, K., additional, Steine, K., additional, Cimino, S., additional, Pedrizzetti, G., additional, Tonti, G., additional, Canali, E., additional, Petronilli, V., additional, Cicogna, F., additional, Arcari, L., additional, De Luca, L., additional, Iacoboni, C., additional, Agati, L., additional, Abdel Moneim, S. S., additional, Eifert Rain, S., additional, Bernier, M., additional, Bhat, G., additional, Hagen, M., additional, Bott-Kitslaar, D., additional, Castello, R., additional, Wilansky, S., additional, Pellikka, P., additional, Mulvagh, S., additional, Delithanasis, I., additional, Celutkiene, J., additional, Kenny, C., additional, Monaghan, M., additional, Park, W., additional, Hong, G., additional, Son, J., additional, Lee, S., additional, Kim, U., additional, Park, J., additional, Shin, D., additional, Kim, Y., additional, Toutouzas, K., additional, Drakopoulou, M., additional, Aggeli, C., additional, Felekos, I., additional, Nikolaou, C., additional, Synetos, A., additional, Stathogiannis, K., additional, Tsiamis, E., additional, Siores, E., additional, Stefanadis, C., additional, Plicht, B., additional, Kahlert, P., additional, Grave, T., additional, Buck, T., additional, Konorza, T., additional, Gursoy, M., additional, Gokdeniz, T., additional, Astarcioglu, M., additional, Bayram, Z., additional, Cakal, B., additional, Karakoyun, S., additional, Kalcik, M., additional, Acar, R., additional, Kahveci, G., additional, Ozkan, M., additional, Tsang, W., additional, Weinert, L., additional, Yurdakul, S., additional, Avci, B., additional, Sahin, S., additional, Dilekci, B., additional, Aytekin, S., additional, Arenga, F., additional, Hascoet, S., additional, Martin, R., additional, Dulac, Y., additional, Peyre, M., additional, Benzouid, C., additional, Hadeed, K., additional, Acar, P., additional, Zakarkaite, D., additional, Skorniakov, V., additional, Zvironaite, V., additional, Grabauskiene, V., additional, Burca, J., additional, Ciparyte, L., additional, Laucevicius, A., additional, Di Salvo, G., additional, Rea, A., additional, D'aiello, A., additional, Del Gaizo, F., additional, Pergola, V., additional, D'andrea, A., additional, Pacileo, G., additional, Calabro, R., additional, Russo, M., additional, Dedobbeleer, C., additional, Hadefi, A., additional, Naeije, R., additional, Unger, P., additional, Mornos, C., additional, Cozma, D., additional, Ionac, A., additional, Mornos, A., additional, Valcovici, M., additional, Pescariu, S., additional, Petrescu, L., additional, Hu, K., additional, Liu, D., additional, Niemann, M., additional, Herrmann, S., additional, Cikes, M., additional, Stoerk, S., additional, Knop, S., additional, Ertl, G., additional, Bijnens, B., additional, Weidemann, F., additional, De Knegt, M., additional, Biering-Sorensen, T., additional, Sogaard, P., additional, Sivertsen, J., additional, Jensen, J., additional, Mogelvang, R., additional, Lam, W., additional, Tang, M., additional, Chan, K., additional, Yang, Y., additional, Fang, F., additional, Sun, J., additional, Yu, C., additional, Lam, Y., additional, Panoulas, V., additional, Sulemane, S., additional, Bratsas, A., additional, Konstantinou, K., additional, Francone, M., additional, Schau, T., additional, Seifert, M., additional, Ridjab, D., additional, Schoep, M., additional, Gottwald, M., additional, Neuss, M., additional, Meyhoefer, J., additional, Zaenker, M., additional, Butter, C., additional, Tarr, A., additional, Stoebe, S., additional, Pfeiffer, D., additional, Hagendorff, A., additional, Maret, E., additional, Ahlander, B.-M., additional, Bjorklund, P.-G., additional, Engvall, J., additional, Staskiewicz, G., additional, Czekajska-Chehab, E., additional, Adamczyk, P., additional, Siek, E., additional, Przybylski, P., additional, Maciejewski, R., additional, Drop, A., additional, Jimenez Rubio, C., additional, Isasti Aizpurua, G., additional, Miralles Ibarra, J., additional, Al-Mallah, M., additional, Somg, T., additional, Alam, S., additional, Chattahi, J., additional, Zweig, B., additional, Dhanalakota, K., additional, Boedeker, S., additional, Ananthasubramaniam, K., additional, Park, C., additional, March, K., additional, Jones, S., additional, Mayet, J., additional, Tillin, T., additional, Chaturvedi, N., additional, Hughes, A., additional, Hamodraka, E., additional, Kallistratos, E., additional, Karamanou, A., additional, Tsoukas, T., additional, Mavropoulos, D., additional, Kouremenos, N., additional, Zaharopoulou, I., additional, Nikolaidis, N., additional, Kremastinos, D., additional, Manolis, A., additional, Loboz-Rudnicka, M., additional, Jaroch, J., additional, Bociaga, Z., additional, Kruszynska, E., additional, Ciecierzynska, B., additional, Dziuba, M., additional, Dudek, K., additional, Uchmanowicz, I., additional, Loboz-Grudzien, K., additional, Silva, D., additional, Magalhaes, A., additional, Jorge, C., additional, Cortez-Dias, N., additional, Carrilho-Ferreira, P., additional, Silva Marques, J., additional, Portela, I., additional, Pascoa, C., additional, Nunes Diogo, A., additional, Brito, D., additional, Roosens, B., additional, Bala, G., additional, Droogmans, S., additional, Hostens, J., additional, Somja, J., additional, Delvenne, E., additional, Schiettecatte, J., additional, Lahoutte, T., additional, Van Camp, G., additional, and Cosyns, B., additional

Published
2012
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10. Transcatheter pulmonary valve replacement after arterial switch operation.

Author

Nageotte S, Salavitabar A, Zablah JE, Ligon RA, Turner ME, El-Said H, Guyon P, Boucek D, Alvarez-Fuente M, McElhinney DB, Balzer D, and Shahanavaz S

Subjects
Humans, Retrospective Studies, Male, Treatment Outcome, Female, Child, Child, Preschool, Time Factors, United States, Adolescent, Feasibility Studies, Risk Factors, Ventricular Function, Right, Infant, Young Adult, Hemodynamics, Adult, Ventricular Outflow Obstruction etiology, Ventricular Outflow Obstruction physiopathology, Ventricular Outflow Obstruction diagnostic imaging, Ventricular Outflow Obstruction surgery, Pulmonary Valve surgery, Pulmonary Valve physiopathology, Pulmonary Valve diagnostic imaging, Cardiac Catheterization adverse effects, Cardiac Catheterization instrumentation, Arterial Switch Operation adverse effects, Transposition of Great Vessels surgery, Transposition of Great Vessels physiopathology, Transposition of Great Vessels diagnostic imaging, Heart Valve Prosthesis Implantation adverse effects, Heart Valve Prosthesis Implantation instrumentation, Pulmonary Valve Insufficiency physiopathology, Pulmonary Valve Insufficiency surgery, Pulmonary Valve Insufficiency etiology, Pulmonary Valve Insufficiency diagnostic imaging, Heart Valve Prosthesis, Pulmonary Valve Stenosis physiopathology, Pulmonary Valve Stenosis surgery, Pulmonary Valve Stenosis diagnostic imaging, Pulmonary Valve Stenosis etiology, Recovery of Function
Abstract

Background: Patients with d-transposition of the great arteries (d-TGA) who have undergone an arterial switch operation (ASO) can develop right ventricular outflow tract (RVOT) dysfunction with pulmonary regurgitation (PR) or stenosis. In these patients, treatment may include transcatheter pulmonary valve replacement (TPVR). Coronary compression is a contraindication occurring in 5% of typical TPVR cases. After ASO, there are various anatomical considerations that can confound TPVR, including potential coronary artery compression. Our goal is to understand feasibility of TPVR in patients following ASO., Methods: This was a retrospective multicenter cohort study of patients with RVOT dysfunction after ASO who underwent cardiac catheterization with intention to perform TPVR from 2008 to 2020., Results: Across nine centers, 33 patients met inclusion criteria. TPVR was successful in 22 patients (66%), 19 receiving a Melody valve and 3 a SAPIEN valve. RVOT stenosis in isolation or with PR dictated need for TPVR in nearly all patients. One serious adverse event occurred with valve embolization. After TPVR, the RVOT peak gradient decreased from 43 to 9 mm Hg (p < 0.001); PR was trivial/none in all but one patient, in whom it was mild. Coronary compression prohibiting TPVR occurred in eight patients (24%) and two patients (6%) had severe aortic regurgitation from aortic root deformation precluding TPVR. Seven patients underwent RVOT reintervention a median of 5.3 years post-TPVR., Conclusions: TPVR in patients with d-TGA after ASO is feasible, but in this cohort, coronary compression or aortic root distortion precluded TPVR in one-third of patients. The rate of RVOT reintervention after TPVR was higher in this cohort of ASO patients than in prior studies., (© 2024 The Author(s). Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.)

Published
2024
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11. SAPIEN valve infective endocarditis after transcatheter pulmonary valve replacement: A European case series.

Author

Lourtet-Hascoët J, Valdeolmillos E, Houeijeh A, Kantzis M, Alvarez-Fuente M, Guérin P, Jones M, Georgiev S, Ystgaard MB, Betrian P, Fraisse A, and Hascoët S

Subjects
Humans, Treatment Outcome, Aortic Valve, Pulmonary Valve diagnostic imaging, Pulmonary Valve surgery, Endocarditis diagnostic imaging, Endocarditis etiology, Heart Valve Prosthesis Implantation adverse effects, Heart Valve Prosthesis, Transcatheter Aortic Valve Replacement adverse effects
Published
2023
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12. Association of the dysfunctional placentation endotype of prematurity with bronchopulmonary dysplasia: a systematic review, meta-analysis and meta-regression.

Author

Pierro M, Villamor-Martinez E, van Westering-Kroon E, Alvarez-Fuente M, Abman SH, and Villamor E

Subjects
Female, Humans, Infant, Newborn, Infant, Premature, Placentation, Pregnancy, Bronchopulmonary Dysplasia epidemiology
Abstract

Background: Antenatal pathological conditions are key in the pathogenesis of bronchopulmonary dysplasia (BPD). Pathophysiological pathways or endotypes leading to prematurity and perinatal lung injury can be clustered into two groups: infection and dysfunctional placentation, which include hypertensive disorders of pregnancy (HDP) and intrauterine growth restriction (IUGR). We conducted a systematic review of observational studies exploring the association between the dysfunctional placentation endotype and BPD., Methods: MEDLINE, Embase and Web of Science databases were searched up to February 2020 for studies reporting data on the diagnosis of HDP, IUGR or small for gestational age (SGA) and BPD risk. BPD was classified as BPD28 (supplemental oxygen on day 28), BPD36 (oxygen at 36 weeks postmenstrual age), severe BPD (≥ 30% oxygen or mechanical ventilation), BPD36/death and BPD-associated pulmonary hypertension., Results: Of 6319 studies screened, 211 (347 963 infants) were included. Meta-analysis showed an association between SGA/IUGR and BPD36 (OR 1.56, 95% CI 1.37 to 1.79), severe BPD (OR 1.82, 95% CI 1.36 to 2.29) and BPD/death (OR 1.91, 95% CI 1.55 to 2.37). Exposure to HDP was not associated with BPD but was associated with decreased odds of BPD/death (OR 0.77, 95% CI 0.64 to 0.94). Both HDP (OR 1.41, 95% CI 1.10 to 1.80) and SGA/IUGR (OR 2.37, 95% CI 1.86 to 3.02) were associated with BPD-associated pulmonary hypertension., Conclusion: When placental vascular dysfunction is accompanied by fetal growth restriction or being born SGA, it is associated with an increased risk of developing BPD and pulmonary hypertension. The placental dysfunction endotype of prematurity is strongly associated with the vascular phenotype of BPD., Prospero Registration Number: Review protocol was registered in PROSPERO database (ID=CRD42018086877)., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2022
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13. Long-Term Complications After Aortic Coarctation Stenting.

Author

Alvarez-Fuente M, Ayala A, Garrido-Lestache E, Bermudez-Cañete R, Garcia-De Vicente A, Toledano M, Sanchez I, Abelleira C, Molina I, and Jesus Del Cerro M

Subjects
Adolescent, Aortic Coarctation diagnosis, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Incidence, Male, Postoperative Complications diagnosis, Postoperative Complications etiology, Spain epidemiology, Tomography, X-Ray Computed, Treatment Outcome, Aortic Coarctation surgery, Forecasting, Postoperative Complications epidemiology, Stents adverse effects, Vascular Surgical Procedures adverse effects
Published
2021
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14. Exploring clinical, echocardiographic and molecular biomarkers to predict bronchopulmonary dysplasia.

Author

Alvarez-Fuente M, Moreno L, Lopez-Ortego P, Arruza L, Avila-Alvarez A, Muro M, Gutierrez E, Zozaya C, Sanchez-Helguera G, Elorza D, Martinez-Ramas A, Villar G, Labrandero C, Martinez L, Casado T, Cuadrado I, and Del Cerro MJ

Subjects
Bronchopulmonary Dysplasia epidemiology, Bronchopulmonary Dysplasia metabolism, Female, Follow-Up Studies, Gestational Age, Humans, Infant, Newborn, Infant, Premature, Diseases epidemiology, Infant, Premature, Diseases metabolism, Longitudinal Studies, Male, Pregnancy, Prognosis, Prospective Studies, Risk Factors, Spain epidemiology, Biomarkers blood, Bronchopulmonary Dysplasia diagnosis, Echocardiography methods, Infant, Extremely Premature blood, Infant, Low Birth Weight blood, Infant, Premature, Diseases diagnosis, Risk Assessment methods
Abstract

Introduction: Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in childhood, related to prematurity, and the most common cause of pulmonary hypertension (PH) secondary to pulmonary disease in children. Moderate and severe BPD have a worse outcome and relate more frequently with PH. The prediction of moderate or severe BPD development in extremely premature newborns is vital to implement preventive strategies. Starting with the hypothesis that molecular biomarkers were better than clinical and echocardiographic factors, this study aims to explore the ability of clinical, echocardiographic and analytical variables to predict moderate or severe BPD in a cohort of extremely preterm infants., Patients and Methods: We designed a prospective longitudinal study, in which we followed a cohort of preterm newborns (gestational age <28 weeks and weight ≤ 1250 grams). In these newborns we recorded weekly clinical and echocardiographic variables as well as blood and tracheal aspirate samples, to analyze molecular biomarkers (IL-6, IL-1, IP10, uric acid, HGF, endothelin-1, VEGF, CCL5). Variables and samples were collected since birth up to week 36 (postmenstrual age), time-point at which the diagnosis of BPD is established., Results: We included 50 patients with a median gestational age of 26 weeks (IQR 25-27) and weight of 871 g (SD 161,0) (range 590-1200g). Three patients were excluded due to an early death. Thirty-five patients (74.5%) developed BPD (mild n = 14, moderate n = 15, severe n = 6). We performed a logistic regression in order to identify risk factors for moderate or severe BPD. We compared two predictive models, one with two variables (mechanical ventilation and inter-ventricular septum flattening), and another-one with an additional molecular biomarker (ET-1)., Conclusions: The combination of clinical and echocardiographic variables is a valuable tool for determining the risk of BPD. We find the two variable model (mechanical ventilation and echocardiographic signs of PH) more practical for clinical and research purposes. Future research on BPD prediction should be oriented to explore the potential role of ET-1., Competing Interests: The authors have declared that no competing interests exist.

Published
2019
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15. Mid-Term Valve-Related Outcomes After Transcatheter Tricuspid Valve-in-Valve or Valve-in-Ring Replacement.

Author

McElhinney DB, Aboulhosn JA, Dvir D, Whisenant B, Zhang Y, Eicken A, Ribichini F, Tzifa A, Hainstock MR, Martin MH, Kornowski R, Schubert S, Latib A, Thomson JDR, Torres AJ, Meadows J, Delaney JW, Guerrero ME, Salizzoni S, El-Said H, Finkelstein A, George I, Gewillig M, Alvarez-Fuente M, Lamers L, Cheema AN, Kreutzer JN, Rudolph T, Hildick-Smith D, and Cabalka AK

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Endocarditis epidemiology, Endocarditis etiology, Endovascular Procedures adverse effects, Heart Valve Prosthesis Implantation adverse effects, Humans, Infant, Middle Aged, Postoperative Complications etiology, Reoperation adverse effects, Retrospective Studies, Thrombosis epidemiology, Thrombosis etiology, Treatment Outcome, Young Adult, Endovascular Procedures mortality, Heart Valve Prosthesis Implantation mortality, Postoperative Complications epidemiology, Reoperation mortality, Tricuspid Valve surgery
Abstract

Background: Transcatheter aortic and pulmonary valves have been used to treat stenosis or regurgitation after prior surgical tricuspid valve (TV) replacement or repair. Little is known about intermediate-term valve-related outcomes after transcatheter tricuspid valve replacement (TTVR), including valve function, thrombus, and endocarditis., Objectives: The authors sought to evaluate mid-term outcomes in a large cohort of patients who underwent TTVR after surgical TV repair or replacement, with a focus on valve-related outcomes., Methods: Patients who underwent TTVR after prior surgical TV replacement or repair were collected through an international registry. Time-related outcomes were modeled and risk factors assessed., Results: Data were collected for 306 patients who underwent TTVR from 2008 through 2017 at 80 centers; 52 patients (17%) had a prior history of endocarditis. Patients were followed for a median of 15.9 months after implantation (0.1 to 90 months), with 64% of patients estimated to be alive without TV reintervention or a valve-related event at 3 years. The cumulative 3-year incidence of death, reintervention, and valve-related adverse outcomes (endocarditis, thrombosis, or significant dysfunction) were 17%, 12%, and 8%, respectively. Endocarditis was diagnosed in 8 patients 2 to 29 months after TTVR, for an annualized incidence rate of 1.5% per patient-year (95% confidence interval: 0.45% to 2.5%). An additional 8 patients were diagnosed with clinically relevant valve thrombosis, 3 in the short term, 2 within 2 months, and 3 beyond 6 months. Only 2 of these 8 patients received anticoagulant therapy before thrombus detection (p = 0.13 vs. patients without thrombus). Prior endocarditis was not a risk factor for reintervention, endocarditis, or valve thrombosis, and there was no difference in valve-related outcomes according to TTVR valve type., Conclusions: TV dysfunction, endocarditis, and leaflet thrombosis were uncommon after TTVR. Patients with prior endocarditis were not at higher risk for endocarditis or other adverse outcomes after TTVR, and endocarditis occurred with similar frequency in different valve types. Though rare, leaflet thrombosis is an important adverse outcome, and further study is necessary to determine the appropriate level of prophylactic therapy after TTVR., (Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)

Published
2019
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