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Nanotechnology is considered a successful approach for cancer diagnosis and treatment. Preferentially, cancer cell recognition and drug targeting via nano‐delivery system include the penetration of anticancer agents into the cell membrane to damage the cancer cell by protein modification, DNA oxidation, or mitochondrial dysfunction. The past research on nano‐delivery systems and their target has proven the beneficial achievement in a malignant tumor. Modern perceptions using inventive nanomaterials for cancer management have been offered by a multifunctional platform based on various nano‐carriers with the probability of imaging and cancer therapy simultaneously. Emerging nano‐delivery systems in cancer therapy still lack knowledge of the biological functions behind the interaction between nanoparticles and cancer cells. Since the potential of engineered nanoparticles addresses the various challenges, limiting the success of cancer therapy subsequently, it is a must to review the molecular targeting of a nano‐delivery system to enhance the therapeutic efficacy of cancer. This review focuses on using a nano‐delivery system, an imaging system, and encapsulated nanoparticles for cancer therapy. [ABSTRACT FROM AUTHOR]

The usage of radiation is mandatory for modern life; in the same manner, controlling the outflow of harmful radiation is vital and could be achieved via employing a shielding material to eliminate any potential nuclear and radiation accidents and incidents. Considering this point, this study aims to manufacture composite samples based on waste marble as novel radiation shields. The physical and radiation shielding ability of the prepared shields were determined and analyzed. For this purpose, a high-purity germanium (HPGe) detector was used to detect the incoming photons emitted from three point sources (Am-241, Cs-137, and Co-60). The radiation attenuation factors for the new marble-based composites were measured for some energies, ranging from 0.06 to 1.333 MeV. We examined the effect of increasing the PbCO3 and CdO contents on the physical properties and radiation attenuation factors of the newly developed radiation shielding absorber. We found that the density of the samples increases from 1.784 to 1.796 g/cm3 when the CdO changes from 0 to 12.5 wt%. The linear attenuation coefficient (LAC) for all marble compositions has the maximum value at 0.06 MeV, while the LAC decreases with increasing energy. The highest LAC was found for Marb-3, with a composition of waste marble (50 wt%), polyester (25 wt%), PbCO3 (17.5 wt%), and CdO (7.5 wt%). We studied the impact of the addition of CdO on the expense of PbCO3 and we found that the half value layer (HVL) decreases with increasing the CdO content. Hence, when there is no space problem, the newly developed radiation shielding absorber can be used to maintain the cost effectiveness and environmentally friendliness of products. [ABSTRACT FROM AUTHOR]