1. Body mass index and fat influences the role of Bifidobacterium genus in lupus patients concerning fibrinogen levels
- Author
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Lourdes Chero-Sandoval, Andrea Higuera-Gómez, Amanda Cuevas-Sierra, Begoña de Cuevillas, Raquel Castejón, María Martínez-Urbistondo, Susana Mellor-Pita, Víctor Moreno-Torres, Daniel de Luis, and J. Alfredo Martínez
- Subjects
Bifidobacterium ,body mass index ,fibrinogen ,low-grade metabolic inflammation ,systemic lupus erythematosus ,Microbiology ,QR1-502 - Abstract
IntroductionMetabolic disorders and autoimmune diseases elicit distinct yet interconnected manifestations of inflammation, which may be boosted by an excess of body adiposity. The purpose of this investigation was to analyze anthropometric, biochemical, and inflammatory/coagulation variables concerning patients diagnosed with systemic lupus erythematosus (SLE) exploiting low-grade metabolic inflammation (MI), as reference.MethodsA population stratification by body mass index (BMI), allowed to assess the impact of adiposity on the putative role of gut microbiota composition on coagulation markers. A total of 127 participants with MI and SLE were categorized into two main groups based on their BMI, following WHO criteria: a low BMI group (
- Published
- 2024
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