1. Surveillance and management of Echinococcus multilocularis in a wildlife park
- Author
-
Jean-Marc Boucher, Frédéric Grenouillet, Amandine Guenon, Damien Montange, Vanessa Hormaz, Franck Boué, Jennifer Lahoreau, Gérald Umhang, Agence Nationale de Sécurité Sanitaire, de l'Alimentation, de l'environnement et du Travail ( ANSES ), ANSES, Laboratoire Génie des procédés papetiers ( LGP2 ), Centre Technique du Papier ( CTP ) -Institut National Polytechnique de Grenoble ( INPG ) -École Française de Papeterie et des Industries Graphiques-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Laboratoire Génie des procédés papetiers (LGP2 ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)
- Subjects
Male ,0301 basic medicine ,Veterinary medicine ,Foxes ,Captivity ,Lemur catta ,Serology ,Feces ,MESH : Antigens, Fungal ,0302 clinical medicine ,Parasite hosting ,MESH : Female ,MESH : Environmental Monitoring ,biology ,Arvicolinae ,030108 mycology & parasitology ,MESH : Adult ,3. Good health ,Intestines ,MESH : Air Pollution, Indoor ,Infectious Diseases ,Liver ,Epidemiological Monitoring ,MESH: Inhalation Exposure ,MESH: Aspergillus fumigatus ,MESH: Environmental Monitoring ,medicine.drug ,Echinococcosis, Hepatic ,MESH: Cystic Fibrosis ,MESH : Male ,030231 tropical medicine ,Animals, Wild ,Rodentia ,Echinococcus multilocularis ,Albendazole ,[ SDV.EE.SANT ] Life Sciences [q-bio]/Ecology, environment/Health ,03 medical and health sciences ,Echinococcosis ,MESH : Cystic Fibrosis ,parasitic diseases ,medicine ,Animals ,MESH : France ,MESH: Antigens, Fungal ,[SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health ,MESH: Humans ,Lemur ,MESH : Humans ,MESH : Aspergillosis, Allergic Bronchopulmonary ,MESH: Adult ,biology.organism_classification ,MESH: Male ,MESH: DNA, Fungal ,MESH: France ,Metacestode ,MESH: Aspergillosis, Allergic Bronchopulmonary ,MESH : Aspergillus fumigatus ,Parasitology ,MESH : Inhalation Exposure ,MESH: Air Pollution, Indoor ,MESH : DNA, Fungal ,MESH: Female - Abstract
International audience; The fox tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a severe zoonotic disease that may be fatal if untreated. A broad spectrum of mammalian species may be accidentally infected even in captivity. In April 2011, liver lesions due to E. multilocularis were observed during the necropsy of a captive-born nutria (Myocastor coypus) in a French wildlife park, leading to initiation of a study to survey the parasite's presence in the park. A comparable environmental contamination with fox's feces infected by E. multilocularis was reported inside (17.8%) and outside (20.6%) the park. E. multilocularis worms were found in the intestines of three of the five roaming foxes shot in the park. Coprological analyses of potential definitive hosts in captivity (fox, lynx, wildcat, genet, wolf, bear and raccoon) revealed infection in one Eurasian wolf. Voles trapped inside the park also had a high prevalence of 5.3%. After diagnosis of alveolar echinococcosis in a Lemur catta during necropsy, four other cases in L. catta were detected by a combination of ultrasound and serology. These animals were treated twice daily with albendazole. The systematic massive metacestode development and numerous protoscoleces in L. catta confirmed their particular sensitivity to E. multilocularis infection. The autochthonous origin of the infection in all the captive animals infected was genetically confirmed by EmsB microsatellite analysis. Preventive measures were implemented to avoid the presence of roaming foxes, contact with potential definitive hosts and contaminated food sources for potential intermediate hosts.
- Published
- 2016