Search

Background: The occurrence of multiple brain tumors of different cellular origins in a single individual is extremely rare. There is limited documentation regarding the incidence of intracranial neoplasms in individuals with preexisting neurocysticercosis (NCC)., Case Description: We report the case of a 43-year-old male who had been under our care since he first suffered from seizures 2½ years ago when he was diagnosed with NCC. A year after the diagnosis of NCC, he presented to the emergency room with seizures, when he was found to have a new small left frontal meningioma, which was managed conservatively. In the next year, the patient was admitted to the emergency room in a disoriented state, and his imaging revealed a new lesion - a left frontal glioma, for which he was operated. Six months later, another glioma was found in the right frontal region, which was excised surgically. Four months after the second surgery, the patient was brought with intractable seizures when he was diagnosed with cerebrospinal fluid spread of NCC. During this admission, the patient expired due to a pulmonary infection., Conclusion: This case report presents the sequential occurrence of neurocysticercosis, meningioma, and glioma in an Indian male patient. The occurrence of NCC with brain tumors is rarely reported in the literature; further research is needed to understand the occurrence of multiple brain tumors, especially in the setting of preexisting NCC., Competing Interests: There are no conflicts of interest., (Copyright: © 2025 Surgical Neurology International.)

Intradiploic epidermoid tumors are uncommon and giant epidermoid with dural involvement is scarcer. We report a unique case of a giant frontal epidermoid tumor presenting without typical features of swelling or bulge in scalp. A 61-year-old male presented with the complaints of forgetfulness and headache. Contrast magnetic resonance imaging brain revealed a large left frontal epidermoid tumor. A tumor measuring 13 × 11 × 4 cm, involving the dura but sparing the brain parenchyma, was excised through left frontal craniotomy. Such a presentation of giant epidermoid tumor with dural involvement is highly unusual. Complete surgical excision is the final aim and vigilant follow-up for recurrence is a must., (Copyright: © International Journal of Health Sciences.)

Sentinel lymph node biopsy is an established practice to avoid axillary clearance, in clinically negative axilla, in breast cancer patients. Sentinel nodes harvested by dual technique, if found negative on intraoperative frozen section, can prevent breast cancer patient from a potentially debilitating complete axillary clearance. Hence, analyzing the institutional accuracy of this technique and comparing it with international standards, becomes important in providing optimal treatment to these patients. A retrospective analysis of all patients who had undergone sentinel lymph node biopsy at our institute from December 2014 to December 2018 was carried out. At our institute, sentinel lymph nodes are identified using dual technique of methylene blue and radiocolloid dye. Intraoperative frozen section of these hot or blue or any enlarged nodes is performed. Patients with positive frozen section undergo complete axillary clearance. All frozen and unfrozen biopsy material is subjected to further paraffin sectioning and immunohistochemistry. False negative rate and factors associated with were analyzed. A total number of 424 patients had undergone intraoperative frozen section for the sentinel node in breast cancer at our institute during the study period. Among these, 307 patients had negative sentinel nodes and 117 had positive sentinel nodes of frozen section. Seventeen patients out of 307 had lymph node metastases in final paraffin report (false negative rate = 12.6%). Two of these were found to have macrometastasis, 13 had micrometastasis and 2 had isolated tumor cells on final immunohistochemistry report. Size of metastases to sentinel lymph node was found to be a statistically significant contributor to higher false negative rate. Sentinel lymph node biopsy using intraoperative frozen section, is a sensitive and specific technique of staging axilla in breast cancer patients. Detection of micrometastasis and isolated tumor cells present a technical challenge and are associated with higher false negative rates., Competing Interests: Conflict of InterestThe authors declare no competing interests., (© Indian Association of Surgical Oncology 2021.)