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29 results on '"Amenaghawon, Andrew N."'

5. Anaerobic co-digestion of cattle rumen content and food waste for biogas production: Establishment of co-digestion ratios and kinetic studies

Author

Ihoeghian, Newton A., Amenaghawon, Andrew N., Ajieh, Mike U., Oshoma, Cyprian E., Ogofure, Abraham, Erhunmwunse, Nosakhare O., Edosa, Valerie I.O., Tongo, Isioma, Obuekwe, Ifeyinwa S., Isagba, Ebuwa S., Emokaro, Christopher, Ezemonye, Lawrence I.N., Lag-Brotons, Alfonso J., Semple, Kirk T., and Martin, Alastair D.

Published
2022
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12. Evaluation of Far‐Field Electrospun Polyvinyl Alcohol/Hyaluronic Acid Nanofibrous Membranes for Skin Tissue Engineering Applications.

Author

Ilomuanya, Margaret O., Bassey, Peace Ofonabasi, Cardoso‐Daodu, Ibilola M., Hou, Yanhao, Nmesirionye, Bright U., Amenaghawon, Andrew N., Ojo, Olusola, Adeosun, Samson A., and Wang, Weiguang

Subjects
TISSUE engineering, POLYVINYL alcohol, HYALURONIC acid, CAPILLARIES, CONTROLLED release drugs, COMPOSITE materials, TISSUES
Abstract

Electrospinning has emerged as one of the major technologies for designing and fabricating tissue engineering membranes. The resemblance of the electrospun fiber structure to blood capillaries endowed them with unique capabilities to mimic the native tissue biological characteristics, while the high surface‐to‐volume ratio enables them to exert a controlled release of drug directly to the exposed interstitial tissue. This research attempts to compare the characteristics of different electrospun polyvinyl alcohol/hyaluronic acid (PVA/HA) composite material nanofibrous membranes in order to identify the optimal material‐fabrication combination for wound dressing and skin tissue engineering applications. Far‐field electrospinning equipped with both rotatory and wire collectors is considered for membrane fabrication. PVA with different concentrations and molecular weights of HA are electrospun as nanofibrous membranes considering a voltage of 30 kV on both types of collectors. Comprehensive characterization is conducted including morphological, chemical, thermal, mechanical, and in vitro mucoadhesion analysis. In vitro cell viability/proliferation studies are also carried out and pointed out that the designed membranes are cytocompatible, and able to support keratinocytes proliferation. All these results proved that the fabricated PVA/HA nanofibrous membranes are suitable for wound dressing and skin tissue engineering applications, the optimal material‐fabrication combination is also determined. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Development of Mucoadhesive Electrospun Scaffolds for Intravaginal Delivery of Lactobacilli spp., a Tenside, and Metronidazole for the Management of Bacterial Vaginosis

Author

Ilomuanya, Margaret O., primary, Bassey, Peace O., additional, Ogundemuren, Deborah A., additional, Ubani-Ukoma, Uloma N., additional, Tsamis, Alkiviadis, additional, Fan, Yuwei, additional, Michalakis, Konstantinos, additional, Angsantikul, Pavimol, additional, Usman, Abdulrahman, additional, and Amenaghawon, Andrew N., additional

Published
2023
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21. Enhanced viability of Lactobacillusspp. via encapsulation in hyaluronan/PVA hybrid electrospun composites for vaginal drug delivery

Author

Ilomuanya, Margaret O., Ogundemuren, Deborah A., Bassey, Peace-OfonAbasi O., Oseni, Bukola A., Kola-Mustapha, Adeola T., Tsamos, Dimitrios, Alkiviadis, Tsamis, Tsouknidas, Alexandros E., and Amenaghawon, Andrew N.

Abstract

Background: Vaginal dysbiosis, a change in the beneficial vaginal microbiome, leads to a significant depletion in the essential lactobacilli thus increasing the possibility of vaginal infections such as bacterial vaginosis. Probiotics have gained more attention as a means of delivering exogenous lactobacilli but one of the challenges in delivery strategies is maintaining and improving their viability. The objective of this study is to enhance the viability of Lactobacillusspp., via encapsulation in hyaluronic acid/polyvinyl alcohol hybrid electrospun nanofibers. Polyvinyl alcohol (PVA) and hyaluronic acid (HA) composite nanofibers integrated with Lactobacillusspp. were fabricated by electrospinning. The survival of Lactobacillusspp. after its immobilization in electrospun nanofibers with polyvinyl alcohol and hyaluronic acid was evaluated. Results: Scanning electron microscopy indicated larger average diameters in PVA/HA nanofibers with Lactobacillusspp. encapsulation (0.189 ± 0.041 µm to 0.231 ± 0.061 µm between D3 and D4, and 0.177 ± 0.043 µm to 0.212 ± 0.041 µm between D5 and D6) which showed that the nanofibers had the bacterial cells successfully enclosed in them. The viability of the lactic acid bacteria enclosed in the PVA/HA nanofibers was observed to decrease by more than 2-log units. Conclusion: The electrospun nanofiber-based delivery system is promising for the encapsulation and delivery of lactic acid bacteria to the vagina to combat recurrent vaginal infections such as bacterial vaginosis.

Published
2024
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22. Contributors

Author

Alia, Telli, Amenaghawon, Andrew N., Aminata, Ould El Hadj-Khelil, Amine, Gacem Mohamed, Anuradha, Anyalewechi, Chinedu L., Ashoka, S., Bucio, Emilio, Delava, Juliana S., Fiorentin-Ferrari, Leila D., Fiorese, Mônica L., Flores-Rojas, Guadalupe Gabriel, Fragoso-Medina, Amira J., Hari Krishna, R., Kumar, Sunil, Kusuma, Heri Septya, López-Saucedo, Felipe, Madhuri, Rashmi, Mahmood, Nasir, Majhi, Kartick Chandra, Manjunatha, C., Sabrine, Darem, Singh, Jagvir, Slusarski-Santana, Veronice, Souza, Héllen K.S., Triques, Carina C., Verma, Rajni, and Yadav, Mahendra

Published
2021
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23. Contributors

Author

Aggarwal, Poonam, Agrawal, Mukta, Ahmad, Mudasir, Ajazuddin, Akram, Sumia, Alexander, Amit, Amado, Franco Rico, Amenaghawon, Andrew N., Anil Kumar, Nanjangud V., Anyalewechi, Chinedu L., Aslam, Raouf, Baghbanbashi, Mojhdeh, Bao, Ming, Bertuol, Daniel Assumpção, Bezerra, F.W.F., Bezerra, P.N., Carvalho Junior, R.N., Chandra, Rajesh, Chaves Neto, A.M.J., Cheikhyoussef, Ahmad, Cheikhyoussef, Natascha, Chong, Gun-Hean, Cordeiro, R.M., Cruz, Estevan Dorneles, Cunha, V.M.B., da Costa, W.A., da Cruz, J.N., de Oliveira, M.S., de Souza, Ana Lúcia Barbosa, Din Reshi, Noor U., Druzian, Janice Izabel, Dubey, Sunil Kumar, Gani, Adil, Gonçalves, Sandra, Hadidi, Naghmeh, Hadzir, Noor Hadzuin Nik, Jafarinejad, Shahryar, Khan, Junaid, Kusuma, Heri Septya, Lee, Wan-Jun, Liu, Xin, Machado, Bruna Aparecida Souza, Mahfud, Mahfud, Matsakas, Leonidas, Moosvi, Syed Kazim, Mushtaq, Muhammad, Patel, Ravish, Patel, Alok, Pazuki, Gholamreza, Pessoa, Fernando Luiz Pellegrini, Pinto, R.H.H., Rehal, Jagbir, Reis, João Henrique de Oliveira, Rizvi, Masood Ahmad, Romano, Anabela, Saraf, Shailendra, Saraf, Swarnlata, Sartaj, Km, Siddique, Sabahuddin, Silva, M.P., Suali, Emma, Suleiman, Norhidayah, Sunil, Dhanya, Tanabe, Eduardo Hiromitsu, Vahdat, Nader, Wang, Wan-Hui, Yadav, Pooja, Yaqoob, Mudasir, and Zabot, Giovani L.

Published
2020
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