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1. Residential exposure to transportation noise and risk of incident atrial fibrillation: a pooled study of 11 prospective Nordic cohorts

Author

Thacher, Jesse D., Roswall, Nina, Ögren, Mikael, Pyko, Andrei, Åkesson, Agneta, Oudin, Anna, Rosengren, Annika, Poulsen, Aslak H., Eriksson, Charlotta, Segersson, David, Rizzuto, Debora, Helte, Emilie, Andersson, Eva M., Aasvang, Gunn Marit, Engström, Gunnar, Gudjonsdottir, Hrafnhildur, Selander, Jenny, Christensen, Jesper H., Brandt, Jørgen, Leander, Karin, Overvad, Kim, Mattisson, Kristoffer, Eneroth, Kristina, Stucki, Lara, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Raaschou-Nielsen, Ole, Jousilahti, Pekka, Tiittanen, Pekka, Ljungman, Petter L.S., Jensen, Steen S., Gustafsson, Susanna, Yli-Tuomi, Tarja, Cole-Hunter, Thomas, Lanki, Timo, Lim, Youn-Hee, Andersen, Zorana J., Pershagen, Göran, and Sørensen, Mette

Published
2024
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3. Long-term exposure to air pollution and chronic kidney disease-associated mortality–Results from the pooled cohort of the European multicentre ELAPSE-study

Author

Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, and Nagel, Gabriele

Published
2024
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4. Long-term air pollution exposure and malignant intracranial tumours of the central nervous system: a pooled analysis of six European cohorts

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K. E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023
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6. Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project

Author

Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Published
2024
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7. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2024
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8. Association between exposure to multiple air pollutants, transportation noise and cause-specific mortality in adults in Switzerland

Author

Vienneau, Danielle, Stafoggia, Massimo, Rodopoulou, Sophia, Chen, Jie, Atkinson, Richard W., Bauwelinck, Mariska, Klompmaker, Jochem O., Oftedal, Bente, Andersen, Zorana J., Janssen, Nicole A. H., So, Rina, Lim, Youn-Hee, Flückiger, Benjamin, Ducret-Stich, Regina, Röösli, Martin, Probst-Hensch, Nicole, Künzli, Nino, Strak, Maciek, Samoli, Evangelia, de Hoogh, Kees, Brunekreef, Bert, and Hoek, Gerard

Published
2023
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9. Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Forastiere, Francesco, Brynedal, Boel, Hertel, Ole, Hoffmann, Barbara, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023
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11. Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts

Author

Thacher, Jesse D., Oudin, Anna, Flanagan, Erin, Mattisson, Kristoffer, Albin, Maria, Roswall, Nina, Pyko, Andrei, Aasvang, Gunn Marit, Andersen, Zorana J., Borgquist, Signe, Brandt, Jørgen, Broberg, Karin, Cole-Hunter, Thomas, Eriksson, Charlotta, Eneroth, Kristina, Gudjonsdottir, Hrafnhildur, Helte, Emilie, Ketzel, Matthias, Lanki, Timo, Lim, Youn-Hee, Leander, Karin, Ljungman, Petter, Manjer, Jonas, Männistö, Satu, Raaschou-Nielsen, Ole, Pershagen, Göran, Rizzuto, Debora, Sandsveden, Malte, Selander, Jenny, Simonsen, Mette K., Stucki, Lara, Spanne, Mårten, Stockfelt, Leo, Tjønneland, Anne, Yli-Tuomi, Tarja, Tiittanen, Pekka, Valencia, Victor H., Ögren, Mikael, Åkesson, Agneta, and Sørensen, Mette

Published
2023
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12. Comparison of traditional Cox regression and causal modeling to investigate the association between long-term air pollution exposure and natural-cause mortality within European cohorts

Author

Wolf, Kathrin, Rodopoulou, Sophia, Chen, Jie, Andersen, Zorana J., Atkinson, Richard W., Bauwelinck, Mariska, Janssen, Nicole A.H., Kristoffersen, Doris Tove, Lim, Youn-Hee, Oftedal, Bente, Strak, Maciek, Vienneau, Danielle, Zhang, Jiawei, Brunekreef, Bert, Hoek, Gerard, Stafoggia, Massimo, and Samoli, Evangelia

Published
2023
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13. Long-term exposure to elemental components of fine particulate matter and all-natural and cause-specific mortality in a Danish nationwide administrative cohort study

Author

So, Rina, Chen, Jie, Stafoggia, Massimo, de Hoogh, Kees, Katsouyanni, Klea, Vienneau, Danielle, Samoli, Evangelia, Rodopoulou, Sophia, Loft, Steffen, Lim, Youn-Hee, Westendorp, Rudi G.J., Amini, Heresh, Cole-Hunter, Thomas, Bergmann, Marie, Shahri, Seyed Mahmood Taghavi, Zhang, Jiawei, Maric, Matija, Mortensen, Laust H., Bauwelinck, Mariska, Klompmaker, Jochem O., Atkinson, Richard W., Janssen, Nicole A.H., Oftedal, Bente, Renzi, Matteo, Forastiere, Francesco, Strak, Maciek, Brunekreef, Bert, Hoek, Gerard, and Andersen, Zorana J.

Published
2023
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14. Long-term exposure to traffic noise and risk of incident colon cancer: A pooled study of eleven Nordic cohorts

Author

Roswall, Nina, Thacher, Jesse D., Ögren, Mikael, Pyko, Andrei, Åkesson, Agneta, Oudin, Anna, Tjønneland, Anne, Rosengren, Annika, Poulsen, Aslak H., Eriksson, Charlotta, Segersson, David, Rizzuto, Debora, Helte, Emilie, Andersson, Eva M., Aasvang, Gunn Marit, Gudjonsdottir, Hrafnhildur, Khan, Jibran, Selander, Jenny, Christensen, Jesper H., Brandt, Jørgen, Leander, Karin, Mattisson, Kristoffer, Eneroth, Kristina, Stucki, Lara, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Spanne, Mårten, Jousilahti, Pekka, Tiittanen, Pekka, Molnàr, Peter, Ljungman, Petter L.S., Yli-Tuomi, Tarja, Cole-Hunter, Thomas, Lanki, Timo, Hvidtfeldt, Ulla A., Lim, Youn-Hee, Andersen, Zorana J., Pershagen, Göran, and Sørensen, Mette

Published
2023
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16. Long-term air pollution exposure and Parkinson’s disease mortality in a large pooled European cohort: An ELAPSE study

Author

Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A., Jöckel, Karl-Heinz, Mortensen, Laust H., Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C.H., Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, and Andersen, Zorana J.

Published
2023
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17. Long-Term Exposure to Low-Level P[M.sub.2.5] and Mortality: Investigation of Heterogeneity by Harmonizing Analyses in Large Cohort Studies in Canada, United States, and Europe

Author

Chen, Jie, Braun, Danielle, Christidis, Tanya, Cork, Michael, Rodopoulou, Sophia, Samoli, Evangelia, Stafoggia, Massimo, Wolf, Kathrin, Wu, Xiao, Yuchi, Weiran, Andersen, Zorana J., Atkinson, Richard, Bauwelinck, Mariska, de Hoogh, Kees, Janssen, Nicole A.H., Katsouyanni, Klea, Klompmaker, Jochem O., Kristoffersen, Doris Tove, Lim, Youn-Hee, Oftedal, Bente, Strak, Maciej, Vienneau, Danielle, Zhang, Jiawei, Burnett, Richard T., Hoek, Gerard, Dominici, Francesca, Brauer, Michael, and Brunekreef, Bert

Subjects
Mortality -- Statistics -- Environmental aspects -- Health aspects -- Europe -- Canada -- United States, Air pollution -- Statistics -- Health aspects, Particles -- Statistics -- Health aspects, Environmental issues, Health
Abstract

BACKGROUND: Studies across the globe generally reported increased mortality risks associated with particulate matter with aerodynamic diameter [less than or equal to]2.5 [micro]m (P[M.sub.2.5]) exposure with large heterogeneity in the magnitude of reported associations and the shape of concentration-response functions (CRFs). We aimed to evaluate the impact of key study design factors (including confounders, applied exposure model, population age, and outcome definition) on P[M.sub.2.5] effect estimates by harmonizing analyses on three previously published large studies in Canada [Mortality-Air Pollution Associations in Low Exposure Environments (MAPLE), 1991-2016], the United States (Medicare, 2000-2016), and Europe [Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE), 2000-2016] as much as possible. METHODS: We harmonized the study populations to individuals 65+ years of age, applied the same satellite-derived P[M.sub.2.5] exposure estimates, and selected the same sets of potential confounders and the same outcome. We evaluated whether differences in previously published effect estimates across cohorts were reduced after harmonization among these factors. Additional analyses were conducted to assess the influence of key design features on estimated risks, including adjusted covariates and exposure assessment method. A combined CRF was assessed with meta-analysis based on the extended shape-constrained health impact function (eSCHIF). RESULTS: More than 81 million participants were included, contributing 692 million person-years of follow-up. Hazard ratios and 95% confidence intervals (CIs) for all-cause mortality associated with a 5-[micro]g/[m.sup.3] increase in P[M.sub.2.5] were 1.039 (1.032, 1.046) in MAPLE, 1.025 (1.021, 1.029) in Medicare, and 1.041 (1.014, 1.069) in ELAPSE. Applying a harmonized analytical approach marginally reduced difference in the observed associations across the three studies. Magnitude of the association was affected by the adjusted covariates, exposure assessment methodology, age of the population, and marginally by outcome definition. Shape of the CRFs differed across cohorts but generally showed associations down to the lowest observed P[M.sub.2.5] levels. A common CRF suggested a monotonically increased risk down to the lowest exposure level. https://doi.org/10.1289/EHP12141, Introduction Ambient particulate matter (PM) pollution has been identified as a leading risk factor for global disease burden. (1) Evaluating the risks attributable to PM with aerodynamic diameter [less than [...]

Published
2023
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18. Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project

Author

Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Taj, Tahir, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Verschuren, W. M. Monique, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Boutron-Ruault, Marie-Christine, Magnusson, Patrik K. E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, van der Schouw, Yvonne T., Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Raaschou-Nielsen, Ole, and Hoek, Gerard

Published
2022
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19. Variability in the association between long-term exposure to ambient air pollution and mortality by exposure assessment method and covariate adjustment: A census-based country-wide cohort study

Author

Bauwelinck, Mariska, Chen, Jie, de Hoogh, Kees, Katsouyanni, Klea, Rodopoulou, Sophia, Samoli, Evangelia, Andersen, Zorana J., Atkinson, Richard, Casas, Lidia, Deboosere, Patrick, Demoury, Claire, Janssen, Nicole, Klompmaker, Jochem O., Lefebvre, Wouter, Mehta, Amar Jayant, Nawrot, Tim S., Oftedal, Bente, Renzi, Matteo, Stafoggia, Massimo, Strak, Maciek, Vandenheede, Hadewijch, Vanpoucke, Charlotte, Van Nieuwenhuyse, An, Vienneau, Danielle, Brunekreef, Bert, and Hoek, Gerard

Published
2022
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20. Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project

Author

Stafoggia, Massimo, Oftedal, Bente, Chen, Jie, Rodopoulou, Sophia, Renzi, Matteo, Atkinson, Richard W, Bauwelinck, Mariska, Klompmaker, Jochem O, Mehta, Amar, Vienneau, Danielle, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, de Hoogh, Kees, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Kristoffersen, Doris Tove, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter L S, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Rizzuto, Debora, Schramm, Sara, Schwarze, Per E, Severi, Gianluca, Sigsgaard, Torben, Strak, Maciek, van der Schouw, Yvonne T, Verschuren, Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Samoli, Evangelia, Forastiere, Francesco, Brunekreef, Bert, Hoek, Gerard, and Janssen, Nicole A H

Published
2022
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22. #506 Long-term exposure to air pollution and CKD-associated mortality: results from the pooled cohort of the European multicentre ELAPSE-study

Author

Zitt, Emanuel, primary, Kadelbach, Pauline, additional, Chen, Jie, additional, Jaensch, Andrea, additional, de Hoogh, Kees, additional, Andersen, Zorana J, additional, Samoli, Evangelia, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, Nagel, Gabriele, additional, and Weinmayr, Gudrun, additional

Published
2024
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23. Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project

Author

Wolf, Kathrin, Hoffmann, Barbara, Andersen, Zorana J, Atkinson, Richard W, Bauwelinck, Mariska, Bellander, Tom, Brandt, Jørgen, Brunekreef, Bert, Cesaroni, Giulia, Chen, Jie, de Faire, Ulf, de Hoogh, Kees, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hvidtfeldt, Ulla Arthur, Janssen, Nicole A H, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O, Lager, Anton, Liu, Shuo, MacDonald, Conor J, Magnusson, Patrik K E, Mehta, Amar J, Nagel, Gabriele, Oftedal, Bente, Pedersen, Nancy L, Pershagen, Göran, Raaschou-Nielsen, Ole, Renzi, Matteo, Rizzuto, Debora, Rodopoulou, Sophia, Samoli, Evangelia, van der Schouw, Yvonne T, Schramm, Sara, Schwarze, Per, Sigsgaard, Torben, Sørensen, Mette, Stafoggia, Massimo, Strak, Maciek, Tjønneland, Anne, Verschuren, W M Monique, Vienneau, Danielle, Weinmayr, Gudrun, Hoek, Gerard, Peters, Annette, and Ljungman, Petter L S

Published
2021
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24. Long-term exposure to several constituents and sources of PM 2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project.

Author

Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Abstract

It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM 2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO 2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for traffic and residual oil combust

Published
2024

25. Long-term exposure to transportation noise and obesity : A pooled analysis of eleven Nordic cohorts

Author

Persson, Asa, Pyko, Andrei, Stucki, Lara, Ogren, Mikael, Akesson, Agneta, Oudin, Anna, Tjonneland, Anne, Rosengren, Annika, Segersson, David, Rizzuto, Debora, Helte, Emilie, Andersson, Eva M., Aasvang, Gunn Marit, Gudjonsdottir, Hrafnhildur, Selander, Jenny, Christensen, Jesper H., Leander, Karin, Mattisson, Kristoffer, Eneroth, Kristina, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Spanne, Marten, Roswall, Nina, Tiittanen, Pekka, Molnar, Peter, Ljungman, Petter L. S., Mannisto, Satu, Yli-Tuomi, Tarja, Cole-Hunter, Thomas, Lanki, Timo, Lim, Youn-Hee, Andersen, Zorana J., Sorensen, Mette, Pershagen, Goran, Eriksson, Charlotta, Persson, Asa, Pyko, Andrei, Stucki, Lara, Ogren, Mikael, Akesson, Agneta, Oudin, Anna, Tjonneland, Anne, Rosengren, Annika, Segersson, David, Rizzuto, Debora, Helte, Emilie, Andersson, Eva M., Aasvang, Gunn Marit, Gudjonsdottir, Hrafnhildur, Selander, Jenny, Christensen, Jesper H., Leander, Karin, Mattisson, Kristoffer, Eneroth, Kristina, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Spanne, Marten, Roswall, Nina, Tiittanen, Pekka, Molnar, Peter, Ljungman, Petter L. S., Mannisto, Satu, Yli-Tuomi, Tarja, Cole-Hunter, Thomas, Lanki, Timo, Lim, Youn-Hee, Andersen, Zorana J., Sorensen, Mette, Pershagen, Goran, and Eriksson, Charlotta

Published
2024
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26. Harnessing AI to unmask Copenhagen's invisible air pollutants: A study on three ultrafine particle metrics

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Amini, Heresh, Bergmann, Marie L, Taghavi Shahri, Seyed Mahmood, Tayebi, Shali, Cole-Hunter, Thomas, Kerckhoffs, Jules, Khan, Jibran, Meliefste, Kees, Lim, Youn-Hee, Mortensen, Laust H, Hertel, Ole, Reeh, Rasmus, Gaarde Nielsen, Christian, Loft, Steffen, Vermeulen, Roel, Andersen, Zorana J, Schwartz, Joel, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Amini, Heresh, Bergmann, Marie L, Taghavi Shahri, Seyed Mahmood, Tayebi, Shali, Cole-Hunter, Thomas, Kerckhoffs, Jules, Khan, Jibran, Meliefste, Kees, Lim, Youn-Hee, Mortensen, Laust H, Hertel, Ole, Reeh, Rasmus, Gaarde Nielsen, Christian, Loft, Steffen, Vermeulen, Roel, Andersen, Zorana J, and Schwartz, Joel

Published
2024

27. Long-term exposure to several constituents and sources of PM 2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project.

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Published
2024

28. Long-term exposure to air pollution and chronic kidney disease-associated mortality - results from the pooled cohort of the European multicentre ELAPSE-study

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch Dipl-Dok, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Prof Francesco, Gulliver, Prof John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Prof Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Prof Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Prof Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, Nage, Prof Gabriele, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch Dipl-Dok, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Prof Francesco, Gulliver, Prof John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Prof Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Prof Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Prof Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, and Nage, Prof Gabriele

Published
2024

29. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2024

30. Long-term exposure to air pollution and incidence of gastric and the upper aerodigestive tract cancers in a pooled European cohort: The ELAPSE project

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Nagel, Gabriele, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel C H, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, Weinmayr, Gudrun, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Nagel, Gabriele, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel C H, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, and Weinmayr, Gudrun

Published
2024

31. Air pollution and human health:a phenome-wide association study

Author

Hegelund, Emilie Rune, Mehta, Amar J, Andersen, Zorana J, Lim, Youn-Hee, Loft, Steffen, Brunekreef, Bert, Hoek, Gerard, de Hoogh, Kees, Mortensen, Laust Hvas, Hegelund, Emilie Rune, Mehta, Amar J, Andersen, Zorana J, Lim, Youn-Hee, Loft, Steffen, Brunekreef, Bert, Hoek, Gerard, de Hoogh, Kees, and Mortensen, Laust Hvas

Abstract

OBJECTIVES: To explore the associations of long-term exposure to air pollution with onset of all human health conditions.DESIGN: Prospective phenome-wide association study.SETTING: Denmark.PARTICIPANTS: All Danish residents aged ≥30 years on 1 January 2000 were included (N=3 323 612). After exclusion of individuals with missing geocoded residential addresses, 3 111 988 participants were available for the statistical analyses.MAIN OUTCOME MEASURE: First registered diagnosis of every health condition according to the International Classification of Diseases, 10th revision, from 2000 to 2017.RESULTS: Long-term exposure to fine particulate matter (PM 2.5) and nitrogen dioxide (NO 2) were both positively associated with the onset of more than 700 health conditions (ie, >80% of the registered health conditions) after correction for multiple testing, while the remaining associations were inverse or insignificant. As regards the most common health conditions, PM 2.5 and NO 2 were strongest positively associated with chronic obstructive pulmonary disease (PM 2.5: HR 1.06 (95% CI 1.05 to 1.07) per 1 IQR increase in exposure level; NO 2: 1.14 (95% CI 1.12 to 1.15)), type 2 diabetes (PM 2.5: 1.06 (95% CI 1.05 to 1.06); NO 2: 1.12 (95% CI 1.10 to 1.13)) and ischaemic heart disease (PM 2.5: 1.05 (95% CI 1.04 to 1.05); NO 2: 1.11 (95% CI 1.09 to 1.12)). Furthermore, PM 2.5 and NO 2 were both positively associated with so far unexplored, but highly prevalent outcomes relevant to public health, including senile cataract, hearing loss and urinary tract infection. CONCLUSIONS: The findings of this study suggest that air pollution has a more extensive impact on human health than previously known. However, as this study is the first of its kind to investigate the associations of long-term exposure to air pollution with onset of all human health conditions, further research is needed to replicate the study findings.

Published
2024

32. Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer:Results from the large pooled European cohort of the ELAPSE project

Author

Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Abstract

It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for t, It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for traffic and

Published
2024

34. Long-Term Exposure to Transportation Noise and Ischemic Heart Disease: A Pooled Analysis of Nine Scandinavian Cohorts

Author

Pyko, Andrei, Roswall, Nina, Ogren, Mikael, Oudin, Anna, Rosengren, Annika, Eriksson, Charlotta, Segersson, David, Rizzuto, Debora, Andersson, Eva M., Aasvang, Gunn Marit, Engstrom, Gunnar, Gudjonsdottir, Hrafnhildur, Jorgensen, Jeanette T., Selander, Jenny, Christensen, Jesper H., Brandt, Jorgen, Leander, Karin, Overvad, Kim, Eneroth, Kristina, Mattisson, Kristoffer, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Tiittanen, Pekka, Molnar, Peter, Ljungman, Petter, Jensen, Steen Solvang, Gustafsson, Susanna, Lanki, Timo, Lim, Youn-Hee, Andersen, Zorana J., Sorensen, Mette, and Pershagen, Goran

Subjects
Transportation noise -- Health aspects -- Environmental aspects, Noise pollution -- Health aspects, Myocardial ischemia -- Risk factors -- Environmental aspects, Environmental issues, Health
Abstract

Background: Transportation noise may induce cardiovascular disease, but the public health implications are unclear. Objectives: The study aimed to assess exposure-response relationships for different transportation noise sources and ischemic heart disease (IHD), including subtypes. Methods: Pooled analyses were performed of nine cohorts from Denmark and Sweden, together including 132,801 subjects. Time-weighted longterm exposure to road, railway, and aircraft noise, as well as air pollution, was estimated based on residential histories. Hazard ratios (HRs) were calculated using Cox proportional hazards models following adjustment for lifestyle and socioeconomic risk factors. Results: A total of 22,459 incident cases of IHD were identified during follow-up from national patient and mortality registers, including 7,682 cases of myocardial infarction. The adjusted HR for IHD was 1.03 [95% confidence interval (CI) 1.00, 1.05] per 10 dB [L.sub.den] for both road and railway noise exposure during 5 y prior to the event. Higher risks were indicated for IHD excluding angina pectoris cases, with HRs of 1.06 (95% CI: 1.03, 1.08) and 1.05 (95% CI: 1.01, 1.08) per 10 dB [L.sub.den] for road and railway noise, respectively. Corresponding HRs for myocardial infarction were 1.02 (95% CI: 0.99, 1.05) and 1.04 (95% CI: 0.99, 1.08). Increased risks were observed for aircraft noise but without clear exposure-response relations. A threshold at around 55 dB [L.sub.den] was suggested in the exposure-response relation for road traffic noise and IHD. Discussion: Exposure to road, railway, and aircraft noise in the prior 5 y was associated with an increased risk of IHD, particularly after exclusion of angina pectoris cases, which are less well identified in the registries. https://doi.org/10.1289/EHP10745, Introduction Exposure to traffic noise is increasing because of ongoing urbanization, densification of urban settlements, and growth of the transport sector. In 2017, 113 million Europeans were estimated to be [...]

Published
2023
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35. Two Decades of Air Pollution Health Risk Assessment: Insights From the Use of WHO's AirQ and AirQ+ Tools.

Author

Amini, Heresh, Yousefian, Fatemeh, Faridi, Sasan, Andersen, Zorana J., Calas, Ellénore, Castro, Alberto, Cervantes-Martínez, Karla, Cole-Hunter, Thomas, Corso, Magali, Dragic, Natasa, Evangelopoulos, Dimitris, Gapp, Christian, Hassanvand, Mohammad Sadegh, Kim, Ingu, Le Tertre, Alain, Medina, Sylvia, Miller, Brian, Montero, Stephanie, Requia, Weeberb J., and Riojas-Rodriguez, Horacio

Subjects
POLLUTION risk assessment, HEALTH risk assessment, AIR pollution, DATABASE searching
Abstract

Objectives: We evaluated studies that used the World Health Organization's (WHO) AirQ and AirQ+ tools for air pollution (AP) health risk assessment (HRA) and provided best practice suggestions for future assessments. Methods: We performed a comprehensive review of studies using WHO's AirQ and AirQ+ tools, searching several databases for relevant articles, reports, and theses from inception to Dec 31, 2022. Results: We identified 286 studies that met our criteria. The studies were conducted in 69 countries, with most (57%) in Iran, followed by Italy and India (~8% each). We found that many studies inadequately report air pollution exposure data, its quality, and validity. The decisions concerning the analysed population size, health outcomes of interest, baseline incidence, concentration-response functions, relative risk values, and counterfactual values are often not justified, sufficiently. Many studies lack an uncertainty assessment. Conclusion: Our review found a number of common shortcomings in the published assessments. We suggest better practices and urge future studies to focus on the quality of input data, its reporting, and associated uncertainties. [ABSTRACT FROM AUTHOR]

Published
2024
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37. In reply

Author

Uldbjerg, Cecilie S., Wilson, Louise F., Koch, Trine, Christensen, Jane, Dehlendorff, Christian, Priskorn, Lærke, Abildgaard, Julie, Simonsen, Mette K., Lim, Youn-Hee, Andersen, Zorana J., Juul, Anders, Hickey, Martha, and Bräuner, Elvira V.

Published
2022
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39. Long-term exposure to road traffic noise and stroke incidence: a Danish Nurse Cohort study

Author

Cole-Hunter, Tom, Dehlendorff, Christian, Amini, Heresh, Mehta, Amar, Lim, Youn-Hee, Jørgensen, Jeanette T., Li, Shuo, So, Rina, Mortensen, Laust H., Westendorp, Rudi, Hoffmann, Barbara, Bräuner, Elvira V., Ketzel, Matthias, Hertel, Ole, Brandt, Jørgen, Jensen, Steen Solvang, Christensen, Jesper H., Geels, Camilla, Frohn, Lise M., Backalarz, Claus, Simonsen, Mette K., Loft, Steffen, and Andersen, Zorana J.

Published
2021
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40. Corrigendum to “Residential exposure to transportation noise and risk of incident atrial fibrillation: a pooled study of 11 prospective Nordic cohorts” [The Lancet Regional Health – Europe, Volume 46, November 2024, 101091]

Author

Thacher, Jesse D., Roswall, Nina, Ögren, Mikael, Pyko, Andrei, Åkesson, Agneta, Oudin, Anna, Rosengren, Annika, Poulsen, Aslak H., Eriksson, Charlotta, Segersson, David, Rizzuto, Debora, Helte, Emilie, Andersson, Eva M., Aasvang, Gunn Marit, Engström, Gunnar, Gudjonsdottir, Hrafnhildur, Selander, Jenny, Christensen, Jesper H., Brandt, Jørgen, Leander, Karin, Overvad, Kim, Mattisson, Kristoffer, Eneroth, Kristina, Stucki, Lara, Barregard, Lars, Stockfelt, Leo, Albin, Maria, Simonsen, Mette K., Raaschou-Nielsen, Ole, Jousilahti, Pekka, Tiittanen, Pekka, Ljungman, Petter L.S., Jensen, Steen S., Gustafsson, Susanna, Yli-Tuomi, Tarja, Cole-Hunter, Thomas, Lanki, Timo, Lim, Youn-Hee, Andersen, Zorana J., Pershagen, Göran, and Sørensen, Mette

Published
2024
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43. Long‐term exposure to air pollution and incidence of gastric and the upper aerodigestive tract cancers in a pooled European cohort: The ELAPSE project.

Author

Nagel, Gabriele, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, and Magnusson, Patrik K. E.

Subjects
AIR pollution, PROPORTIONAL hazards models, PARTICULATE matter, STOMACH cancer
Abstract

Air pollution has been shown to significantly impact human health including cancer. Gastric and upper aerodigestive tract (UADT) cancers are common and increased risk has been associated with smoking and occupational exposures. However, the association with air pollution remains unclear. We pooled European subcohorts (N = 287,576 participants for gastric and N = 297,406 for UADT analyses) and investigated the association between residential exposure to fine particles (PM2.5), nitrogen dioxide (NO2), black carbon (BC) and ozone in the warm season (O3w) with gastric and UADT cancer. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area‐level. During 5,305,133 and 5,434,843 person‐years, 872 gastric and 1139 UADT incident cancer cases were observed, respectively. For gastric cancer, we found no association with PM2.5, NO2 and BC while for UADT the hazard ratios (95% confidence interval) were 1.15 (95% CI: 1.00–1.33) per 5 μg/m3 increase in PM2.5, 1.19 (1.08–1.30) per 10 μg/m3 increase in NO2, 1.14 (1.04–1.26) per 0.5 × 10−5 m−1 increase in BC and 0.81 (0.72–0.92) per 10 μg/m3 increase in O3w. We found no association between long‐term ambient air pollution exposure and incidence of gastric cancer, while for long‐term exposure to PM2.5, NO2 and BC increased incidence of UADT cancer was observed. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

Taj, Tahir, primary, Chen, Jie, additional, Rodopoulou, Sophia, additional, Strak, Maciej, additional, de Hoogh, Kees, additional, Poulsen, Aslak Harbo, additional, Andersen, Zorana J., additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Zitt, Emanuel, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Jørgensen, Jeanette T., additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Lager, Anton, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter, additional, Severi, Gianluca, additional, Besson, Caroline, additional, Magnusson, Patrik K.E., additional, Nagel, Gabriele, additional, Pershagen, Göran, additional, Peters, Annette, additional, Rizzuto, Debora, additional, Samoli, Evangelia, additional, Sørensen, Mette, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Weinmayr, Gudrun, additional, Wolf, Kathrin, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Raaschou-Nielsen, Ole, additional

Published
2023
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45. Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project

Author

Weinmayr, Gudrun, primary, Chen, Jie, additional, Jaensch, Andrea, additional, Skodda, Lea, additional, Rodopoulou, Sophia, additional, Strak, Maciej, additional, de Hoogh, Kees, additional, Andersen, Zorana J., additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Leander, Karin, additional, Magnusson, Patrik K.E., additional, Pershagen, Göran, additional, Rizzuto, Debora, additional, Samoli, Evangelia, additional, Severi, Gianluca, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Vermeulen, Roel, additional, Wolf, Kathrin, additional, Zitt, Emanuel, additional, Brunekreef, Bert, additional, Thurston, George, additional, Hoek, Gerard, additional, Raaschou-Nielsen, Ole, additional, and Nagel, Gabriele, additional

Published
2023
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48. Is There an Association Between Ambient Air Pollution and Bladder Cancer Incidence? Analysis of 15 European Cohorts

Author

Pedersen, Marie, Stafoggia, Massimo, Weinmayr, Gudrun, Andersen, Zorana J., Galassi, Claudia, Sommar, Johan, Forsberg, Bertil, Olsson, David, Oftedal, Bente, Krog, Norun H., Aamodt, Geir, Pyko, Andrei, Pershagen, Göran, Korek, Michal, De Faire, Ulf, Pedersen, Nancy L., Östenson, Claes-Göran, Fratiglioni, Laura, Sørensen, Mette, Eriksen, Kirsten T., Tjønneland, Anne, Peeters, Petra H., Bueno-de-Mesquita, Bas, Vermeulen, Roel, Eeftens, Marloes, Plusquin, Michelle, Key, Timothy J., Jaensch, Andrea, Nagel, Gabriele, Concin, Hans, Wang, Meng, Tsai, Ming-Yi, Grioni, Sara, Marcon, Alessandro, Krogh, Vittorio, Ricceri, Fulvio, Sacerdote, Carlotta, Ranzi, Andrea, Cesaroni, Giulia, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Stayner, Leslie T., Kogevinas, Manolis, Nieuwenhuijsen, Mark J., Sokhi, Ranjeet, de Hoogh, Kees, Beelen, Rob, Vineis, Paolo, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2018
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50. Long-term exposure to air pollution and incidence of Parkinson’s disease: a Danish nationwide administrative cohort study

Author

Hunter, Thomas Cole, primary, So, Rina, additional, Antic, Sonja, additional, Lim, Youn Hee, additional, Zhang, Jiawei, additional, Mortensen, Laust H., additional, Hoogh, Kees De, additional, Loft, Steffen, additional, Napolitano, George M., additional, Tuffier, Stéphane, additional, Bergmann, Marie L., additional, Maric, Matija, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Andersen, Zorana J., additional

Published
2023
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