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Peptide toxins from marine invertebrates have found use as drugs and in biotechnological applications. Many marine habitats, however, remain underexplored for natural products, and the Southern Ocean is among them. Here, we report toxins from one of the top predators in Antarctic waters: the nemertean worm Parborlasia corrugatus (McIntosh, 1876). Transcriptome mining revealed a total of ten putative toxins with a cysteine pattern similar to that of alpha nemertides, four nemertide-beta-type sequences, and two novel full-length parborlysins. Nemertean worms express toxins in the epidermal mucus. Here, the expression was determined by liquid chromatography combined with mass spectrometry. The findings include a new type of nemertide, 8750 Da, containing eight cysteines. In addition, we report the presence of six cysteine-containing peptides. The toxicity of tissue extracts and mucus fractions was tested in an Artemia assay. Notably, significant activity was observed both in tissue and the high-molecular-weight mucus fraction, as well as in a parborlysin fraction. Membrane permeabilization experiments display the membranolytic activity of some peptides, most prominently the parborlysin fraction, with an estimated EC50 of 70 nM.

Modular battery swap system for work machines The project has developed and demonstrated how a modular battery swap system can be used in electric work machines in various industries. The purpose of the project was to demonstrate innovative technology where battery swap technology enables battery-powered machines in agriculture and forestry. The project has completed the following: 1. Designed and built a modular battery pack for work machines 2. Designed and built an automatic battery swap station 3. Completed a prototype for an autonomous electric agricultural machine 4. Electrically converted a machine for forestry We have succeeded in creating a working battery swap concept. The concept has been shown at several different demo events. The project has received a lot of positive publicity in the media. The project creates opportunities to run work machines in agriculture and forestry without the batteries needing to be unnecessarily large, heavy and expensive to carry with the machine in the field. Building electrified work machines is not a big deal. What is new in this project is that we demonstrate a battery replacement system for work machines - that works in real life! The project group has worked hard together for two years and achieved brilliant results that we are very pleased with. As expected, it took some time to agree on a concept for the common component battery pack, but once it was set, work took off. In the project, we have built seven battery packs, two electric work machines and a battery swap station including electrical system, control system and other adaptations. This would not have been possible without a dedicated and very talented project group!

Data on the strength ratio between agonist and antagonist muscles are frequently examined in sports testing, given its correlation with athletic performance. The purpose of this study was to determine the agonist-to-antagonist ratio of upper body strength in female and male elite Swedish track and field throwers using a new push (bench press) and pull (supine bench row) test device, and to determine its reliability. The study involved eight female and nine male athletes, aged 19–29 years, engaging, respectively, in discus, hammer, and shot put competitions at both national and international levels. The athletes’ maximum isometric force was assessed during the bench press (push) and supine bench row (pull) exercises, respectively, using a custom-built test device. The test–retest reliability of the device was also examined. The total push-to-pull strength ratio for the female throwers was 1.15, whereas male throwers demonstrated a ratio of 1.22. Total push and pull force for the female throwers was significantly less than for the male throwers (5511 N vs. 8970 N, p < 0.001). Intraclass correlation coefficients ranged from 0.93 to 0.96 for the bench press and supine bench row exercise, indicating that the push and pull test device was highly reliable. The main findings of this study were that elite female and male discus, hammer, and shot put throwers exhibited 15% and 22% more pushing (bench press) than pulling (supine bench row) strength. Push and pull strength in the female throwers ranged from 47% to 71% of that of the male throwers. The push and pull test device is a reliable tool in establishing the agonist-to-antagonist ratio of upper body strength of athletes. Coaches and athletes may benefit from examining upper body push and pull strength ratios for training planning and prescription.

This study aimed to investigate the reliability, validity, and sensitivity of spatiotemporal parameters, during sprint skating, of bandy players. Thirty-two well-trained male bandy players (age: 17.8 ± 1.2 years; height: 1.80 ± 0.06 m; body mass: 75.7 ± 1.2 kg) participated in this study. They performed two 80 m linear skating sprints. To calculate the velocities and obtain glide-by-glide spatiotemporal variables, nine timing gates and two skate-mounted inertial measurement units (IMUs) were synchronized and used. The spatiotemporal variables at each step included the glide time, glide length, double support time, double support length, step length, and step frequency. All the spatiotemporal variables were analyzed separately: averaged over 80 m, during the acceleration, and the maximal steady-state phases. The relative and absolute reliability of the spatiotemporal parameters were good (ICC > 0.70; CV < 10%), except for the step frequency during the steady-state phase. The spatiotemporal parameters showed “good” to “satisfactory” sensitivity during the acceleration phase and whole sprint, and “marginal” sensitivity during the steady-state phase. Content validity was confirmed by a low percentage of the shared variance (17.9–34.3%) between the spatiotemporal parameters obtained during the acceleration and steady-state phases. A “stepwise” regression significantly predicted the steady-state skating velocity from the spatiotemporal metrics obtained during the acceleration [F(5,26) = 8.34, p < 0.001, adj. R2 = 0.62] and steady-state phases [F(5,26) = 13.6, p < 0.01, R2 = 0.67]. Only the step frequency obtained in the acceleration phase significantly predicted the maximal skating velocity (p < 0.01), while the glide length and step frequency derived during the steady-state phase significantly added to the prediction (p < 0.01). In conclusion, the spatiotemporal parameters, obtained by two skate-mounted IMUs, were shown to be reliable and sensitive meas, Speed Development and Monitoring in Elite Bandy Players

This study aimed to compare sprint skating profile characteristics of the different playing positions of junior and senior bandy players. In total, 111 male national-level bandy players (age: 20.7 ± 5.0 years, height: 1.80 ± 0.05 m, body mass: 76.4 ± 0.4 kg, training experience: 13.8 ± 5.0 yrs) were tested on their sprint skating profile over 80 m. The main findings were that no differences between positions were found in sprint skating performance (speed and acceleration), but that elite players were in general heavier (p < 0.05) than junior players (80.0 ± 7.1 vs. 73.1 ± 8.1 kg), they could accelerate faster (2.96 ± 0.22 vs. 2.81 ± 0.28 m/s2), and they reached a higher velocity (10.83 ± 0.37 vs. 10.24 ± 0.42 m/s) earlier over 80 m than the junior players. This implies that junior level players should spend more time in power and sprint training to meet the specific demands of playing at a higher, elite level.

In this study, a developed co-simulation method, which couples 1D-fluid and 3D-structural models, has been utilised to simulate wear in a hydraulic percussion unit. The effect of wear is generally detrimental on performance and lifetime for such units, but can also cause catastrophic failure and breakdown, requiring a total overhaul and replacement of core components. One experiment of standard straight impact was performed to investigate the tolerance against seizure. The percussion unit was operated at successively increasing operating pressures, and the level of wear was registered at each step, until seizure occurred. The co-simulation model was used to replicate the running conditions from the experiment to simulate the structural response to be used as input for the wear routine to calculate the wear depth. The wear pattern from the simulations corresponds well to the wear pattern from the experiment. Further, the effect of a misaligned impact on wear development was also studied, as this is a loading situation that typically occurs for hydraulic percussion units. The study demonstrates that the simulation method used has a potential for simulating wear and predicting seizure in hydraulic percussion units., Funding: Epiroc Tools & Attachments Division

In many sports, the hamstring strain injury is a common injury. There is evidence that the Nordic hamstring exercise (NHE), a knee flexor exercise, can reduce hamstring injury risk in athletes. In research on hamstring injury prevention, eccentric-only NHE is typically performed, whereas in sports, it is relatively common for athletes to perform NHE eccentrically-concentrically. Further, NHE strength is generally assessed by measuring knee flexor force through an ankle brace, attached atop of a load cell. An alternative method might be to assess knee flexor force about the knee joint using a force plate. The aim of the study was to investigate differences in peak knee flexor force between eccentric-only and combined eccentric-concentric NHE. The purpose was also to determine the correlation between hamstring force measured at the ankle using a load cell (current gold standard) and force assessed about the knee joint using a force plate during NHE. Fifteen junior and senior elite soccer and track and field athletes (3 women and 12 men aged 17–27 years) performed eccentric NHE (ENHE) in which they leaned forward as far as possible until breakpoint and eccentric-concentric NHE (ECNHE) where they returned to the starting position. A linear encoder measured the position at which peak force occurred during the NHEs. Force assessed at the ankle differed significantly (678 vs. 600 N, p < 0.05), whereas force about the knee joint did not (640 vs. 607 N, p > 0.05) between ENHE and ECNHE (12 and 5% difference, respectively). The forward distance achieved by the participants in cm at breakpoint for ENHE was 37% higher than at the coupling phase for ECNHE (74 vs. 54 cm, p < 0.001). Very strong significant (p < 0.01) correlations were noted between peak force assessed at the ankle and about the knee joint for ENHE and ECNHE, r = 0.96 and r = 0.99, respectively. Our results suggest that ECNHE, where peak knee flexor force was reached with 37% less forward movement, may

There is no research examining female bandy players, which creates a gap of knowledge of female skating performance and its determinants with male skating performance, not only in bandy but also in exercise science in general. Therefore, the aim of this explorative study was to investigate position and playing-level differences in the sprint skating performance and anthropometrics of 74 elite female bandy players (age: 18.9 ± 4.1 years; height: 1.67 ± 0.06 m; body mass: 63.2 ± 7.4 kg). Participants were categorised according to playing level (26 elite and 48 junior elite players) and position (22 defenders, 35 midfielders, and 17 forwards). They were tested on their anthropometric characteristics and sprint linear skating profile over 80 m with the split times measured at 10, 20, 40, 50, 60, 70, and 80 m to calculate the average velocities between these different 10 m intervals. Results revealed that elite players had more training experience, were heavier, could accelerate faster, and reached a higher maximal velocity than the junior elite players (9.52 ± 0.37 vs 8.84 ± 0.40 m/s, respectively). In general, defenders were heavier than forwards, and the elite forwards accelerated faster in the first 10 m than the midfielders (p = 0.041). In summary, playing level and position, body mass, and training experience modulated skating sprint performance. The findings suggest that female junior-level players should spend more time developing skating sprint and acceleration abilities to meet the specific demands of playing at the elite level. Moreover, the coaches and professionals who work with female bandy players should be aware that the development of acceleration ability is more important for forwards.

Hamstring strain injuries are prevalent in many sports. Research has demonstrated that the Nordic hamstring exercise (NHE), a knee-dominant exercise addressing the posterior chain muscles, can aid in reducing the risk of hamstring injuries in athletes. However, most research on hamstring injury prevention has focused on performing the eccentric version of the NHE (NHEECC). In contrast, in sports, it is quite frequent for athletes to use an eccentric–concentric version of the NHE. Additionally, eccentric NHE is typically performed using a slow, controlled tempo. The effect of a fast stretch-shortening cycle NHE (NHESSC) compared to standard slow NHEECC on peak knee flexor force has not been investigated. The aim of the study was therefore to investigate fast NHESSC vs. standard slow NHEECC. Our hypothesis posited that peak knee flexor force would be greater for fast NHESSC compared with standard slow NHEECC. The study involved 22 elite athletes (actively competing in both national and international events) consisting of female (n = 10) and male (n = 7) track and field athletes and male football players (n = 5), aged 17–31 years. The participants performed maximum trials of slow NHEECC and fast NHESSC repetitions in which measurement of bilateral peak knee flexor force was conducted at the ankle with the use of a load cell. During the NHEs, a linear encoder was used to measure both the position where the peak knee flexor force was recorded and the average eccentric velocity. SSC contributed to an enhanced NHE performance, where bilateral absolute peak knee flexor force was 13% higher for fast NHESSC vs. standard slow NHEECC (822 vs. 726 N, p < 0.01, ES = 0.54). Participants achieved a 32% greater forward distance at the breakpoint stage during NHEECC compared to the coupling phase for NHESSC (54 vs. 41 cm, p < 0.001, ES = 1.37). Eccentric average velocity was more than three times higher for NHESSC compared with NHEECC (0.38 vs. 0.12 m/s, p < 0.001, ES = 3.25