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Johan Tham,1 Inga Odenholt,1 Mats Walder,2 Lina Andersson,1 Eva Melander2,3 1Infectious Diseases Unit, Department of Clinical Sciences, Lund University, Malmö, 2Medical Microbiology, Department of Laboratory Medicine, Lund University, Malmö, 3Department of Infection Control, Laboratory Medicine, Skåne County, Sweden Background: It is important to identify patients who are at risk for infections with extended-spectrum β-lactamase (ESBL)-producing bacteria in order to reduce mortality, to avoid spread of resistant bacteria in hospitals, and to minimize the number of patients receiving unnecessary treatment with broad-spectrum antibiotics. A case-control survey among Swedish patients was performed at Skåne University Hospital to identify risk factors for developing an infection with ESBL-producing Escherichia coli in a low endemic country. Methods: We used a computerized database to identify patients with growth of ESBL-producing E. coli (n = 109) in urine or blood cultures and an equal number of controls matched for age and gender with non ESBL-producing E. coli in urine and blood diagnosed between January and October 2008. We used unadjusted P-values. Results: Patients with ESBL-producing E. coli had a significantly (P < 0.05) higher likelihood of having traveled to Asia including Turkey and the Middle East including Egypt (14/58) than the non-ESBL-positive group (4/53). Hospital stay during the previous year (P < 0.04), especially for more than one month, was another significant (P = 0.01) risk factor for infection with ESBL-producing E. coli (8/58). A stay in the surgical department was a further risk factor (P < 0.01). Conclusion: In this study, we identified 22 of 58 (38%) patients with ESBL-producing E. coli by considered significant risk factors before starting antibiotics. Keywords: extended-spectrum β-lactamase, Enterobacteriaceae, resistant bacteria, risk factors, Escherichia coli

El dolor es considerado un signo vital, y es monitorizado tanto como la frecuencia cardiaca, frecuencia respiratoria, tensión arterial y temperatura. De su control depende en gran parte la calidad de vida de nuestros pacientes. Es por esto que requiere ser manejado de manera tal que a partir de él, quien lo presenta pueda desembolverse en sus actividades diarias, familiares, lúdicas, entre otras. Nuestra especialidad, lleva a cabo un papel muy relevante en la atención de los pacientes que sufren dolor, cualquiera sea su origen, utilizando los diferentes recursos de rehabilitación que se tienen a nuestro alcance y aciendo medición del impacto que este genera.

Reportamos el caso de un paciente con enfermedad diabética tipo 1 que sufrió un ACV isquémico lacunar talámico derecho y simultáneamente otro en la pirámide bulbar derecha, con manifestaciones sensitivas y motoras. Este cuadro clínico se consideró asociado a microangiopatía vascular por el antecedente personal de diabetes tipo 1 y debido a que los demás estudios realizados durante la atención médica no mostraron otra causa aparente.

The fission process still remains a main factor that determines the stability of the atomic nucleus of heaviest elements. Fission half-lives vary over a wide range, 10−19−1024 s. Present experimental techniques for the synthesis of the superheavy elements that usually measure α-decay chains are sensitive only in a limited range of half-lives, often 10−5−103 s. In the past years, measurement techniques for very short-lived and very long-lived nuclei were significantly improved at the gas-filled recoil separator TASCA at GSI Darmstadt. Recently, several experimental studies of fission-related phenomena have successfully been performed. In this paper, results on 254−256Rf and 266Lr are presented and corresponding factors for retarding the fission process are discussed.

Introducción: el Evento Cerebro Vascular (ECV) es una patología común en nuestro medio causante de múltiples secuelas y afecciones sociales, laborales y familiares. Impacta de manera importante el sistema de salud por los tratamientos requeridos. Objetivo: medir objetivamente el impacto funcional que genera el ECV a través de escalas NIHSS (severidad) y Barthel, determinando el grado de independencia funcional en los pacientes que lo sufrieron. Diagnosticar factores pronósticos y de riesgo en dicha población. Materiales y métodos: estudio descriptivo; evaluó 50 pacientes con ECV del Hospital Militar Central- Bogotá, con el fin de identificar sus factores pronósticos y de riesgo, aplicando escalas que reflejen el impacto real durante fase inicial (NIHSS antes de 72 horas - BARTHEL a los 8 días). Resultados: el 38% de pacientes presentaron severidad mayor inicial según escala NISHH, mostrando dependencia funcional grave o total al aplicar escala funcional Barthel una semana después. El 8% presentaron independencia funcional con escala Barthel. 16 % fallecieron durante la hospitalización por causas directas o indirectas. Las limitaciones funcionales más frecuente fueron al realizar traslados de silla-cama y deambulación (26%). El 20% presentaron alteración para el control intestinal y vesical. Conclusión: la medición de la discapacidad inicial en Evento Cerebro Vascular, permite identificar aspectos de mayor afección, definir metas individuales de rehabilitación y facilita seguir la evolución natural de la enfermedad. Una semana después del Ictus el 92% de pacientes presenta algún grado de dependencia funcional, por tanto las metas establecidas deben ser claras e individualizadas para una mayor ganancia a largo plazo durante rehabilitación.

Nuclides that are considered to be isotopes of element Z = 115 were produced in the reaction 48Ca + 243Am at the GSI Helmholtzzentrum für Schwerionenforschung Darmstadt. The detector setup TASISpec was used. It was mounted behind the gas-filled separator TASCA. Thirty correlated α-decay chains were found, and the energies of the particles were determined with high precision. Two important spectroscopic aspects of the offline data analysis are discussed in detail: the handling of digitized preamplified signals from the silicon strip detectors, and the energy reconstruction of particles escaping to upstream detectors relying on pixel-by-pixel dead-layer thicknesses.

The heaviest currently known nuclei, which have up to 118 protons, have been produced in Ca48 induced reactions with actinide targets. Among them, the element tennessine (Ts), which has 117 protons, has been synthesized by fusing Ca48 with the radioactive target Bk249, which has a half-life of 327 d. The experiment was performed at the gas-filled recoil separator TASCA. Two long and two short α decay chains were observed. The long chains were attributed to the decay of Ts294. The possible origin of the short-decay chains is discussed in comparison with the known experimental data. They are found to fit with the decay chain patterns attributed to Ts293. The present experimental results confirm the previous findings at the Dubna Gas-Filled Recoil Separator on the decay chains originating from the nuclei assigned to Ts.

With the advent of the Heliophysics/Geospace System Observatory (H/GSO), a complement of multi-spacecraft missions and ground-based observatories to study the space environment, data retrieval, analysis, and visualization of space physics data can be daunting. The Space Physics Environment Data Analysis System (SPEDAS), a grass-roots software development platform (www.spedas.org), is now officially supported by NASA Heliophysics as part of its data environment infrastructure. It serves more than a dozen space missions and ground observatories and can integrate the full complement of past and upcoming space physics missions with minimal resources, following clear, simple, and well-proven guidelines. Free, modular and configurable to the needs of individual missions, it works in both command-line (ideal for experienced users) and Graphical User Interface (GUI) mode (reducing the learning curve for first-time users). Both options have "crib-sheets," user-command sequences in ASCII format that can facilitate record-and-repeat actions, especially for complex operations and plotting. Crib-sheets enhance scientific interactions, as users can move rapidly and accurately from exchanges of technical information on data processing to efficient discussions regarding data interpretation and science. SPEDAS can readily query and ingest all International Solar Terrestrial Physics (ISTP)-compatible products from the Space Physics Data Facility (SPDF), enabling access to a vast collection of historic and current mission data. The planned incorporation of Heliophysics Application Programmer's Interface (HAPI) standards will facilitate data ingestion from distributed datasets that adhere to these standards. Although SPEDAS is currently Interactive Data Language (IDL)-based (and interfaces to Java-based tools such as Autoplot), efforts are under-way to expand it further to work with python (first as an interface tool and potentially even receiving an under-the-hood replacement). We review the SPEDAS development history, goals, and current implementation. We explain its "modes of use" with examples geared for users and outline its technical implementation and requirements with software developers in mind. We also describe SPEDAS personnel and software management, interfaces with other organizations, resources and support structure available to the community, and future development plans.Electronic supplementary materialThe online version of this article (10.1007/s11214-018-0576-4) contains supplementary material, which is available to authorized users.

Fast regrowth from deep roots and rhizomes makes it difficult to mechanically control the perennials Cirsium arvense and Tussilago farfara respectively. It is, however, not clear whether new shoots originate mainly from fragments of roots/rhizomes in upper soil layers or from an intact system below depth of soil cultivation. Here we present results from three experiments with natural infestations of C. arvense, and two with both C. arvense and T. farfara. Plots of 1 m2 were excavated to different depths (13–25 cm), all below‐ground plant parts in the topsoil were collected and thereafter fragments were either returned to or removed from the plots. Regrowth from disturbed plots with removed or returned fragments was compared. The origin of regrown shoots, that is, whether they originated from seeds, intact below‐ground root/rhizome systems or returned fragments, was examined. More C. arvense shoots originated from the intact root system (48%–84%) than from root fragments (16%–52%). The final aboveground biomass was not affected by removal of the top‐soil fragments. For T. farfara, a small proportion (3%) of new shoots originated from the intact rhizome system, and the rest from fragments. We conclude that the intact root system of C. arvense contributes at least as much as root fragments to regrowth after soil cultivation, which might imply that time of treatment and depth of cultivation are crucial for the effect of mechanical control. For T. farfara, the results suggest that tillage equipment with high capacity to fragment the rhizome system will contribute to efficient control. [ABSTRACT FROM AUTHOR]

Short-lived α-decaying nuclei "northeast" of Pb208 in the chart of nuclides were studied using the reaction Ca48+Am243 with the decay station TASISpec at TASCA, GSI Darmstadt. Decay energies and times from pile-up events were extracted with a tailor-made pulse-shape analysis routine and specific α-decay chains were identified in a correlation analysis. Decay chains starting with the even-even Ra220 and its odd-A neighbors, Fr219, and Ra221,219, with a focus on the Ra219→Rn215 decay, were studied by means of α-γ spectroscopy. A revised α-decay scheme of Ra219 is proposed, including a new decay branch from a previously not considered isomeric state at 17 keV excitation energy. Conclusions on nuclear structure are drawn from the experimental data, aided by Geant4 simulations and a discussion on theoretical calculations.

The isotopic distribution of nuclei produced in the 50Ti + 249Cf reaction has been studied at the gas-filled recoil separator TASCA at GSI Darmstadt, which separates ions according to differences in magnetic rigidity. The bombardment was performed at an energy around the Bass barrier and with the TASCA magnetic fields set for collecting fusion-evaporation reaction products. Fifty-three isotopes located “north-east” of 208Pb were identified as recoiling products formed in non-fusion channels of the reaction. These recoils were implanted with energies in two distinct ranges; besides one with higher energy, a significant low-energy contribution was identified. The latter observation was not expected to occur according to kinematics of the known types of reactions, namely quasi-elastic, multi-nucleon transfer, deep-inelastic collisions or quasifission. The present observations are discussed within the framework of two-body kinematics passing through the formation of a composite system.

Boundaries between space plasmas occur in numerous contexts and scales, from astrophysical jets to planetary magnetospheres. Mass and momentum transport across boundaries poses a fundamental problem in magnetospheric physics. Kelvin-Helmholtz instability (KHI) is a promising mechanism to facilitate transport. Although previous studies have suggested KHI occurrence in various space plasmas, theory predicts that compressibility prevents KHI excitation at boundaries with large density gradients because of previously considered boundary structures where density varies with velocity. Based on the observations of a large density gradient boundary by MAVEN at Mars, where we can observe an extreme case, in this study, we show that it is the entropy, instead of the previously considered density, that varies with the velocity in the real velocity-sheared boundary. The entropy-based boundary structure places the velocity shear in a lower-density region than the traditional density-based structure and weakens the compressibility effect. This new boundary structure thus enables KHI excitation even at large density gradient boundaries, such as at the ionopause of unmagnetized planets and the plasmapause of magnetized planets. The result suggests the ubiquitous occurrence of KHI in the plasma universe and emphasizes its important role in planetary cold plasma escape from unmagnetized planets. [ABSTRACT FROM AUTHOR]

Products of the fusion-evaporation reaction 48Ca + 243Am were studied with the TASISpec set-up at the gas-filled separator TASCA at the GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany. Amongst the detected thirty correlated α-decay chains associated with the production of element Z=115, two recoil-α-fission and five recoil-α-α-fission events were observed. The latter five chains are similar to four such events reported from experiments performed at the Dubna gas-filled separator, and three such events reported from an experiment at the Berkeley gas-filled separator. The four chains observed at the Dubna gas-filled separator were assigned to start from the 2n-evaporation channel 289115 due to the fact that these recoil-α-α-fission events were observed only at low excitation energies. Contrary to this interpretation, we suggest that some of these recoil-α-α-fission decay chains, as well as some of the recoil-α-α-fission and recoil-α-fission decay chains reported from Berkeley and in this article, start from the 3n-evaporation channel 288115.

Produced in the reaction 48Ca+243Am, thirty correlated α-decay chains were observed in an experiment conducted at the GSI Helmholzzentrum für Schwerionenforschung, Darmstadt, Germany. The decay chains are basically consistent with previous findings and are considered to originate from isotopes of element 115 with mass numbers 287, 288, and 289. A set-up aiming specifically for high-resolution charged particle and photon coincidence spectroscopy was placed behind the gas-filled separator TASCA. For the first time, γ rays as well as X-ray candidates were observed in prompt coincidence with the α-decay chains of element 115.

To identify the atomic number of superheavy nuclei produced in 48Ca-induced fusion-evaporation reactions, an experiment aiming at measuring characteristic X-rays is being prepared at GSI, Darmstadt, Germany. The gas-filled separator TASCA will be employed, sending the residues towards the multi-coincidence detector setup TASISpec. Two ionoptical modes relying on differing magnetic polarities of the quadrupole magnets can be used at TASCA. New simulations and experimental tests of transmission and background suppression for these two focusing modes into TASISpec are presented.