40 results on '"Andrea Quarti"'
Search Results
2. Pericardiectomy for Pleuropericardial Effusion Complicating Bacterial Pneumonia
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Andrea Quarti, Fernando Maria de Benedictis, Elli Soura, and Marco Pozzi
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Medicine - Abstract
Severe pericardial effusion is a rare complication of bacterial pneumonia and it usually disappears under medical treatment. Herein we report a case of a girl with a congenital immunodeficient syndrome and bacterial pneumonia, who developed recurrent and life-threatening pericardial effusion refractory to medical treatment. She was finally treated with pericardiectomy.
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- 2010
- Full Text
- View/download PDF
3. Reimplantation of an Anomalous Coronary Artery Arising from the Pulmonary Artery
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Andrea Quarti, Alessandro D'Alfonso, Massimo Colaneri, Alessandra Baldinelli, Maria Grazia Bettuzzi, and Marco Pozzi
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Medicine - Abstract
A case of anomalous origin of the left coronary artery from the pulmonary artery in a patient with the origin of the coronary opposite to the aorta is reported. Between many surgical options we conclude to reestablish a double coronary system reconnecting the coronary through a conduit created with a pulmonary wall baffle and an autologous pericardial patch.
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- 2009
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4. Aortopulmonary Collateral Artery from the Proximal Ascending Aorta: A Rare Anatomical Finding
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Tammam Hasan, Emanuela Angeli, Andrea Quarti, Lucio Careddu, Gabriele Egidy Assenza, Gaetano Gargiulo, Francesco Dimitri Petridis, Andrea Donti, Careddu, Lucio, Angeli, Emanuela, Assenza, Gabriele Egidy, Hasan, Tammam, Quarti, Andrea, Petridis, Francesco Dimitri, Donti, Andrea, and Gargiulo, Gaetano Domenico
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Male ,medicine.medical_specialty ,Vascular Malformations ,Tetralogy of Fallot, Fallot Pulmonary Atresia, MPACAs ,Collateral Circulation ,Pulmonary Artery ,030204 cardiovascular system & hematology ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,medicine.artery ,Internal medicine ,Ascending aorta ,medicine ,Humans ,Aorta ,Tetralogy of Fallot ,Unusual case ,business.industry ,Angiography ,Infant, Newborn ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,030228 respiratory system ,Echocardiography ,Pediatrics, Perinatology and Child Health ,cardiovascular system ,Cardiology ,Surgery ,Blood supply ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,Pulmonary atresia ,business ,Artery - Abstract
Tetralogy of Fallot with pulmonary atresia and major aortopulmonary collateral arteries is a rare congenital heart lesion in which pulmonary blood supply may arise from different segments of the aorta. We report an unusual case of a newborn with a major collateral artery originating from the proximal ascending aorta. Successful reparative surgery was undertaken.
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- 2020
5. A Misdiagnosed Case of Double Outlet Right Atrium Associated With Hypoplastic Right Ventricle
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Claudia Raineri, Domenica Paola Basile, Angelo Fabio D'Aiello, Irene Raso, Andrea Quarti, Alessandro Giamberti, Mario Carminati, Antonio Saracino, Massimo Chessa, Raso, Irene, Quarti, Andrea, Chessa, Massimo, Basile, Domenica Paola, Saracino, Antonio, D'Aiello, Angelo Fabio, Raineri, Claudia, Carminati, Mario, and Giamberti, Alessandro
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Heart Septal Defects, Ventricular ,Male ,Cardiac Catheterization ,Heart disease ,Swine ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Diagnostic Error ,Heart Septal Defects, Atrial ,Heart Ventricle ,0302 clinical medicine ,Pathognomonic ,Cardiac Surgical Procedure ,Medicine ,Cardiac catheterization ,Heart septal defect ,Tricuspid valve ,medicine.diagnostic_test ,General Medicine ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Echocardiography ,cardiovascular system ,Cardiology ,Heterografts ,Tricuspid Valve ,Heterograft ,Cardiology and Cardiovascular Medicine ,Pericardium ,Human ,medicine.medical_specialty ,Heart Ventricles ,Ventricular Septum ,Young Adult ,03 medical and health sciences ,Internal medicine ,Animals ,Humans ,Heart Atria ,cardiovascular diseases ,Interventricular septum ,Cardiac Surgical Procedures ,Diagnostic Errors ,Cyanosis ,Cyanosi ,Animal ,business.industry ,Magnetic resonance imaging ,medicine.disease ,030228 respiratory system ,Ventricle ,Pediatrics, Perinatology and Child Health ,Surgery ,business - Abstract
Double outlet right atrium (DORA) is a rare congenital heart disease in which the right atrium opens into both ventricles. The reduced leftward motion of the interventricular septum causes a malalignment between the atrial and the ventricular septum at the cardiac crux, which is the pathognomonic feature of this heart defect. We describe a case of significant exertional desaturation in an adult patient who was diagnosed with DORA, restrictive right ventricle, and anomalous tricuspid valve. Subsequently, the patient underwent one-and-a-half ventricular palliation.
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- 2020
6. Synthesis and characterization of polysaccharide- and protein-based edible films and application as packaging materials for fresh fish fillets
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Evmorfia Athanasopoulou, Francesco Bigi, Enrico Maurizzi, Eva Iris Eleftheria Karellou, Christos S. Pappas, Andrea Quartieri, and Theofania Tsironi
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Medicine ,Science - Abstract
Abstract The rising packaging industry together with global demand for sustainable production has increased the interest in developing biodegradable packaging materials. The aim of the study was to develop edible films based on pectin, gelatin, and hydroxypropyl methylcellulose and evaluate their applicability as biodegradable packaging materials for gilthead seabream fillets. Mechanical properties, water barriers, wettability of the films through contact angle measurement, optical, and UV–Vis barrier properties were evaluated for food packaging applications. The effective blend of polysaccharide and protein film-forming solutions was confirmed by the produced films with excellent optical properties, acceptable mechanical properties and adequate barriers to water vapor. The contact angle for pectin based and gelatin based films were higher than 90° indicating the hydrophobic films, while HPMC based films had contact angle lower than 90°. The produced films were tested as alternative and environmentally friendly packaging materials for gilthead seabream fillets during refrigerated storage. All tested packaging conditions resulted in similar shelf-life in packed gilthead seabream fillets (i.e. 7–8 days at 2 °C). The results showed that the developed films may reduce the use of conventional petroleum-based food packaging materials without affecting the shelf-life of fish.
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- 2024
- Full Text
- View/download PDF
7. Myocardial oxygen consumption during histidine-tryptophan-ketoglutarate cardioplegia in young human hearts
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Francesco Dimitri Petridis, Anna Balducci, Lucio Careddu, Cristina Ciuca, Gaetano Gargiulo, Luca Ragni, Andrea Donti, Sabrina Martens, Assunta Fabozzo, Emanuela Angeli, Andrea Quarti, Angeli, Emanuela, Martens, Sabrina, Careddu, Lucio, Petridis, Francesco D, Quarti, Andrea G, Ciuca, Cristina, Balducci, Anna, Fabozzo, Assunta, Ragni, Luca, Donti, Andrea, and Gargiulo, Gaetano D
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Pulmonary and Respiratory Medicine ,Male ,medicine.medical_specialty ,Immature myocardium ,030204 cardiovascular system & hematology ,Fick principle ,Histidine-tryptophan-ketoglutarate ,03 medical and health sciences ,Congenital ,0302 clinical medicine ,Myocardial oxygen consumption ,Oxygen Consumption ,Medicine ,Animals ,Humans ,In patient ,Histidine ,030212 general & internal medicine ,Cardioplegic Solutions ,Aorta ,Myocardial protection ,Energy demand ,Crystalloid cardioplegia ,business.industry ,Myocardium ,Infant, Newborn ,Tryptophan ,Heart ,Crystalloid Solutions ,Coronary Vessels ,Cardiac surgery ,Perfusion ,Anesthesia ,Heart Arrest, Induced ,Ketoglutaric Acids ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Anaerobic exercise - Abstract
OBJECTIVES Energy demand and supply need to be balanced to preserve myocardial function during paediatric cardiac surgery. After a latent aerobic period, cardiac cells try to maintain energy production by anaerobic metabolism and by extracting oxygen from the given cardioplegic solution. Myocardial oxygen consumption (MVO2) changes gradually during the administration of cardioplegia. METHODS MVO2 was measured during cardioplegic perfusion in patients younger than 6 months of age (group N: neonates; group I: infants), with a body weight less than 10 kg. Histidine-tryptophan-ketoglutarate crystalloid solution was used for myocardial protection and was administered during a 5-min interval. To measure pO2 values during cardioplegic arrest, a sample of the cardioplegic fluid was taken from the inflow line before infusion. Three fluid samples were taken from the coronary venous effluent 1, 3 and 5 min after the onset of cardioplegia administration. MVO2 was calculated using the Fick principle. RESULTS The mean age of group N was 0.2 ± 0.09 versus 4.5 ± 1.1 months in group I. The mean weight was 3.1 ± 0.2 versus 5.7 ± 1.6 kg, respectively. MVO2 decreased similarly in both groups (min 1: 0.16 ± 0.07 vs 0.36 ± 0.1 ml/min; min 3: 0.08 ± 0.04 vs 0.17 ± 0.09 ml/min; min 5: 0.05 ± 0.04 vs 0.07 ± 0.05 ml/min). CONCLUSIONS We studied MVO2 alterations after aortic cross-clamping and during delivery of cardioplegia in neonates and infants undergoing cardiac surgery. Extended cardioplegic perfusion significantly reduces energy turnover in hearts because the balance procedures are both volume- and above all time-dependent. A reduction in MVO2 indicates the necessity of a prolonged cardioplegic perfusion time to achieve optimized myocardial protection.
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- 2020
8. Evolution of a rare ECG pattern in an aggressive case of neonatal tuberous sclerosis complex
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Marco Pozzi, Andrea Quarti, Alessandro Capestro, Federica Iezzi, Francesca Chiara Surace, Iezzi F., Quarti A., Capestro A., Surace F.C., and Pozzi M.
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Pathology ,medicine.medical_specialty ,Rhabdomyoma-like cell ,Diffuse rhadbomyomatosi ,030204 cardiovascular system & hematology ,Rhabdomyoma-like cells ,Article ,03 medical and health sciences ,Hemodynamically stable ,Tuberous sclerosis ,0302 clinical medicine ,medicine ,cardiovascular diseases ,030212 general & internal medicine ,Organ system ,Cardiac Tumors ,ST-elevation ,Neurocutaneous Disorder ,business.industry ,Increased fibrosis ,fungi ,food and beverages ,medicine.disease ,Diffuse rhadbomyomatosis ,cardiovascular system ,Surgery ,Electrical conduction system of the heart ,business - Abstract
Highlights • Cardiac rhabdomyomas may alter intracardiac electrical conduction. • Rhabdomyoma arrhythmias are caused by isolated atrial depolarization disturbances. • Destruction of conduction system has been described in diffuse rhabdomyomatosis., Introduction Rhabdomyomas are the most frequent cardiac tumors in children. Furthermore, they are often associated to tuberous sclerosis complex, an autosomal dominant neurocutaneous disorder characterized by tumor-like malformations that involve many organ systems. Presentation of the case We describe a rare ECG pattern in a severe case of neonatal tuberous sclerosis complex. Discussion In the presence of significant rhabdomyomatosis related to tuberous sclerosis, multiple clusters of rhabdomyoma-like cells can infiltrate the myocardium, with increased fibrosis areas. Conclusion Considering the fact that rhabdomyomas often show spontaneous regression, close follow-up is sufficient in hemodynamically stable cases. Destruction of the conduction system, with arrhythmias as consequence, can be the presenting feature of diffuse rhabdomyomatosis.
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- 2018
9. Everolimus-induced near-resolution of giant cardiac rhabdomyomas and large renal angiomyolipoma in a newborn with tuberous sclerosis complex
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Andrea Quarti, Massimo Colaneri, Marco Pozzi, Colaneri M., Quarti A., and Pozzi M.
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Male ,Pathology ,medicine.medical_specialty ,Angiomyolipoma ,Antineoplastic Agents ,tuberous sclerosis complex ,030204 cardiovascular system & hematology ,Rhabdomyoma ,Heart Neoplasms ,Antineoplastic Agent ,Lesion ,03 medical and health sciences ,Tuberous sclerosis ,Heart Neoplasm ,0302 clinical medicine ,Tuberous Sclerosis ,030225 pediatrics ,medicine ,Humans ,Everolimus ,Cardiac rhabdomyoma ,medicine.diagnostic_test ,business.industry ,everolimu ,Infant, Newborn ,Infant ,Kidney Neoplasm ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Magnetic Resonance Imaging ,Kidney Neoplasms ,Treatment Outcome ,Echocardiography ,Pediatrics, Perinatology and Child Health ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Human ,medicine.drug ,Renal angiomyolipoma - Abstract
We report a case of a newborn, affected by tuberous sclerosis complex, with a prenatally diagnosed giant cardiac rhabdomyoma associated with a large renal angiomyolipoma presenting as a duct-depending lesion not treatable by surgery. After receiving everolimus, a mammalian target of rapamycin inhibitor, we observed a rapid, significant, and durable reduction of both lesions without remarkable side effects.
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- 2016
10. Outcome of long-term complications after permanent metallic left bronchial stenting in children
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Roberto Leone, Marco Pozzi, Bruno Murzi, Paola Serio, Stefano Avenali, Roberto Baggi, Fabio Midulla, Marco Di Maurizio, Andrea Quarti, Raffaella Nenna, Lorenzo Mirabile, Luigi Arcieri, Serio P., Nenna R., Di Maurizio M., Avenali S., Leone R., Baggi R., Arcieri L., Murzi B., Quarti A., Pozzi M., Mirabile L., and Midulla F.
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Nitinol stent ,Long term complications ,Male ,Airway stenting ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,0302 clinical medicine ,Postoperative Complications ,Bronchoscopy ,Retrospective Studie ,Stent ,Medicine ,Child ,Children ,medicine.diagnostic_test ,Left mainstem bronchu ,General Medicine ,Computed tomographic angiography ,left mainstem bronchus ,medicine.anatomical_structure ,Treatment Outcome ,Child, Preschool ,Female ,Stents ,Cardiology and Cardiovascular Medicine ,Human ,Pulmonary and Respiratory Medicine ,Bronchial Disease ,medicine.medical_specialty ,Bronchi ,03 medical and health sciences ,Humans ,cardiovascular diseases ,Retrospective Studies ,Bronchus ,business.industry ,airway stenting ,children ,complication ,Infant, Newborn ,Aortopexy ,Infant ,Bronchial Diseases ,equipment and supplies ,Surgery ,030228 respiratory system ,Postoperative Complication ,business ,Complication ,Tomography, X-Ray Computed - Abstract
OBJECTIVES: We describe the way we treated 7 children with critical long-term complications after metallic balloon-expandable stenting in the left mainstem bronchus. METHODS: Endoscopic follow-up included a first bronchoscopy 3 weeks after stenting, then monthly for 3 months, every 4-6 months up to 1 year and at scheduled times to calibrate stent diameter up to final calibration. When major complications occurred, patients underwent chest computed tomographic angiography. RESULTS: In 1 of the 7 children (median age 2.8 years), metallic left bronchial stenting served as a bridge to surgery. After a median 4-year follow-up, all 7 children experienced recurrent stent ovalizations with stent breakage in 3 and erosion in 1. In 4 children, computed tomographic angiography showed abundant peribronchial fibrous tissue, in 2 left mediastinal rotation and in 1 displacement along the left bronchus after pulmonary re-expansion as the cause of stent-related complication. Of the 7 children, 6 underwent surgery (5 posterior aortopexy and 1 section of the ligamentum arteriosus) and 3 required nitinol stents placement within the metallic ones. One patient completed the follow-up, and 1 patient was lost to follow-up. All 5 remaining children still have permanent bronchial stents in place, patent and re-epithelialized after a median 10.5-year follow-up. There were no deaths. CONCLUSIONS: Satisfactory anatomical relationships when children have stents placed in the left mainstem bronchus alone do not guarantee the final success. Several mechanisms intervene to cause critical stent-related complications in children during growth. Permanent metallic stents should be used carefully, and only in selected patients.
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- 2017
11. Obstructive neonatal atrial myxoma
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Marco Pozzi, Federica Iezzi, Andrea Quarti, Alessandro Capestro, Iezzi F., Quarti A., Capestro A., and Pozzi M.
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medicine.medical_specialty ,Tricuspid valve ,business.industry ,Atrial myxoma ,Myxoma ,Case Report ,Blood flow ,medicine.disease ,Newborn ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Cardiac chamber ,medicine ,cardiovascular system ,030211 gastroenterology & hepatology ,Fossa ovalis ,cardiovascular diseases ,Cardiac myxoma ,Presentation (obstetrics) ,business ,Interatrial septum - Abstract
Highlights • In the foetus a tumour can be noted on a routine antenatal anomaly scan as an intracardiac mass. • In postnatal life cardiac tumours may affect the integrity and function of the adjacent cardiac structures leading to severely compromised blood flow. • Because of the potential life-threatening sequelae of cardiac myxoma, treatment consists of urgent surgical resection., Introduction Cardiac myxoma is a benign neoplasm representing the most common primary cardiac tumor in adults, however it is unusual in neonates. It is represented by an endocardial mass that occupies the cardiac chamber. Although the majority of myxomas are attached to the fossa ovalis of the interatrial septum, they also attach to the walls of the cardiac chambers and to valve leaflets surfaces. Approximately 75% of myxomas are found in the left atrium, 20% are located in the right atrium, and rarely in the ventricles. Presentation of case We describe a rare case of neonatal cardiac myxoma arising from interatrial septum, causing significant mechanical obstruction to blood flow through tricuspid valve, in an otherwise normal newborn. The patient underwent successful excision of the myxoma with an uneventful recovery [1]. Discussion Cardiac tumors are rare in children, thus an understanding of the common types of benign and malignant paediatric cardiac tumors and their imaging features, is important because the epidemiology and tumor types differ from those encountered in adults. Conclusion Large neonatal myxoma is exceptionally rare and even more infrequent is the surgical excision in the first day of life.
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- 2017
12. Anterior and Posterior Leaflets Augmentation to Treat Tricuspid Valve Regurgitation
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Massimo Colaneri, Federica Iezzi, Marco Pozzi, Andrea Quarti, and Elli Soura
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Pulmonary and Respiratory Medicine ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Tricuspid valve ,business.industry ,Treatment outcome ,technology, industry, and agriculture ,Follow up studies ,Surgery ,medicine.anatomical_structure ,Internal medicine ,cardiovascular system ,medicine ,Cardiology ,lipids (amino acids, peptides, and proteins) ,cardiovascular diseases ,Tricuspid Valve Regurgitation ,Cardiology and Cardiovascular Medicine ,business - Abstract
In congenital non-Ebstein anomalies of the tricuspid valve, the septal leaflet is often involved and tethered. We describe a standardized approach to address septal leaflet tethering by concomitant augmentation of the anterior and posterior leaflets.
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- 2014
13. Paediatric Nonfunctioning Adrenocortical Carcinoma with Extension up to Right-Side Heart: Cardiac Surgery Approach
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Chiara Surace, Marco Pozzi, Andrea Quarti, Federica Iezzi, Iezzi, Federica, Quarti, Andrea, Surace, Chiara, and Pozzi, Marco
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Pathology ,medicine.medical_specialty ,lcsh:Diseases of the circulatory (Cardiovascular) system ,Adrenal carcinoma ,Case Report ,030230 surgery ,Malignancy ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Rare case ,adrenocortical carcinoma ,Carcinoma ,Medicine ,Adrenocortical carcinoma ,business.industry ,Adrenal gland ,medicine.disease ,Cardiac surgery ,medicine.anatomical_structure ,Late diagnosis ,lcsh:RC666-701 ,030220 oncology & carcinogenesis ,Cardiology ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Adrenocortical carcinoma is a rare malignancy. Due to late diagnosis and no adequate effective adjuvant treatment, prognosis remains poor. Only approximately 30% of these malignancies are confined to the adrenal gland when they are diagnosed, as these tumors tend to be found years after their genesis. Cardiac involvement of adrenal carcinoma is very rare. We report a rare case of a 7-year-old female with right adrenal cortical carcinoma, involving the right-side heart.
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- 2016
14. We have to be pioneers: We owe it to the future generations
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Andrea Quarti and Quarti A.
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Pulmonary and Respiratory Medicine ,business.industry ,Medicine ,pioneers ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Classics - Published
- 2015
15. Early and mid-term clinical experience with extracellular matrix scaffold for congenital cardiac and vascular reconstructive surgery: A multicentric Italian study
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Marco Pozzi, Anna C. Frigo, Massimo A. Padalino, Emanuela Angeli, Vladimiro L. Vida, Andrea Quarti, Giovanni Stellin, Gaetano Gargiulo, Padalino, Massimo A, Quarti, Andrea, Angeli, Emanuela, Frigo, Anna C., Vida, Vladimiro L., Pozzi, Marco, Gargiulo, Gaetano, and Stellin, Giovanni
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Aortic valve ,Male ,Time Factors ,Heart disease ,Swine ,Biopsy ,Kaplan-Meier Estimate ,Congenital ,Postoperative Complications ,Risk Factors ,Prospective Studies ,Child ,Heart Defects ,Outcome ,Heart Valve Prosthesis Implantation ,Congenital heart disease ,Extracellular matrix ,Outcomes ,Scaffold ,Small intestine submucosa ,Surgery ,Adolescent ,Adult ,Animals ,Blood Vessel Prosthesis Implantation ,Child, Preschool ,Extracellular Matrix ,Female ,Heart Defects, Congenital ,Heterografts ,Humans ,Infant ,Infant, Newborn ,Italy ,Middle Aged ,Prosthesis Design ,Prosthesis Failure ,Reoperation ,Treatment Outcome ,Young Adult ,Bioprosthesis ,Blood Vessel Prosthesis ,Heart Valve Prosthesis ,Tissue Scaffolds ,Cardiology and Cardiovascular Medicine ,Pulmonary and Respiratory Medicine ,medicine.anatomical_structure ,medicine.medical_specialty ,Reconstructive surgery ,Aneurysm ,medicine.artery ,medicine ,Preschool ,Surgical repair ,Interventional cardiology ,business.industry ,medicine.disease ,Newborn ,Pulmonary artery ,business ,Calcification - Abstract
OBJECTIVES The aim of this multicentric study was to outline surgical indications and evaluate mid-term outcomes of porcine extracellular matrix (ECM) in surgery for congenital heart disease (CHD). METHODS The use of ECM was categorized into four major groups: A, valve repair; B, septal reconstruction; C, arterial plasty; D, other use. Primary endpoints of analysis were reintervention (either surgical or interventional) when related to ECM, and functional ECM failure. Secondary endpoints were evidence of calcification and of persistent inflammation at follow-up. RESULTS One hundred and three patients (M/F = 61/42, median age 19.7 months, 1 day-62 years) underwent surgical repair for CHD. Among ECM use categories, 38 patients were in Group A, 16 in Group B, 71 in Group C and 7 in Group D. There were neither complications nor deaths related to ECM. At a median follow-up of 23.3 months (0.3–55.2), 19 patients underwent reoperation (ECM-related in 6); 11 patients underwent interventional cardiology procedures (ECM-related in 8). Reinterventions were significantly more frequent on the aortic valve (surgical, P = 0.0056) and pulmonary arteries (interventional, P = 0.0159). In addition, interventional procedures on pulmonary arteries were significantly more frequent in infants
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- 2015
16. Anterior and posterior leaflets augmentation to treat tricuspid valve regurgitation
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Andrea, Quarti, Federica, Iezzi, Elli, Soura, Massimo, Colaneri, and Marco, Pozzi
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Adult ,Male ,Young Adult ,Treatment Outcome ,Adolescent ,Humans ,Female ,Tricuspid Valve ,Middle Aged ,Cardiac Valve Annuloplasty ,Tricuspid Valve Insufficiency ,Follow-Up Studies - Abstract
In congenital non-Ebstein anomalies of the tricuspid valve, the septal leaflet is often involved and tethered. We describe a standardized approach to address septal leaflet tethering by concomitant augmentation of the anterior and posterior leaflets.
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- 2014
17. Acute effects of beating heart coronary surgery on left ventricular performance
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Andrea Quarti, Gennaro Ismeno, Lucia Torracca, Jan J. Schreuder, Vincenzo Franzé, Ottavio Alfieri, Torracca, L, Schreuder, Jj, Quarti, A, Ismeno, G, Franze, V, Alfieri, Ottavio, Torracca L., Schreuder J.J., Quarti A., Ismeno G., Franze V., and Alfieri O.
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Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Cardiac Volume ,Cardiac index ,Hemodynamics ,Blood Pressure ,Anterior Descending Coronary Artery ,Ventricular Function, Left ,beating heart left ventricular performance ,Heart Rate ,Internal medicine ,medicine.artery ,Humans ,Medicine ,Coronary Artery Bypass ,Aged ,Cardiopulmonary Bypass ,business.industry ,Middle Aged ,Preload ,Blood pressure ,medicine.anatomical_structure ,Anesthesia ,Pulmonary artery ,Cardiology ,Female ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Artery - Abstract
Background. The increasing use of off-pump bypass grafting (OPCABG), requires an evaluation of its effects on left ventricular (LV) performance. Methods. In 8 patients with multivessel coronary disease who were undergoing to off-pump coronary artery bypass grafting, LV performance was analyzed from the pressure-volume (P-V) plane by the conductance catheter technique. Measurements were performed at base line, after the exposure of the vessels, after the application of the stabilization system, and at the end of the procedure. Results. No significant changes in heart rate, LV end-systolic volume, LV end-diastolic pressure, mean pulmonary artery, and mean systemic blood pressure were observed in the various stages of the procedure. Cardiac index decreased during left anterior descending coronary artery grafting after application of the stabilizer with a concomitant decrease in LV end-diastolic volume, together with decreases in LV peak negative -dP/dt and increases in τ, indicating an impairment of LV relaxation but without a change in preload recruitable stroke work, indicating preserved LV contractile state. Exposure of posterior and lateral vessels induced a decrease in cardiac index and preload recruitable stroke work without a decrease in LV preload, indicating a decrease in LV contractile state together with a decrease in peak -dP/dt and increase in τ, indicating an impairment in LV relaxation. Conclusions. Off-pump coronary artery bypass grafting can be performed without decreasing LV performance. Major cardiac displacement like that used for posterior and lateral exposure induces acutely significant decrease in LV contractile state. © 2002 by The Society of Thoracic Surgeons.
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- 2002
18. Tetralogy of fallot
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Marco Pozzi, Andrea Quarti, Antonio F. Corno, Pozzi, M., Quarti, A., and Corno, A. F.
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medicine.medical_specialty ,business.industry ,Cyanotic congenital heart disease ,Heart defect ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,Internal medicine ,Pulmonary valve ,medicine ,Cardiology ,cardiovascular system ,Tetralogy of Fallot ,Ventricular outflow tract ,business - Abstract
The optimal management of patients with tetralogy of Fallot has to consider the individual intra-cardiac anatomy as the most important variable, together with the age and the body weight of the patient. In any case the potential advantages of a primary early repair should be weighted against the experience and expertise of the individual centre and/or surgical team in dealing with tetralogy of Fallot and with neonates and infants. The best results are achieved by very carefully adapting the surgical technique to the individual morphology of the right ventricular outflow tract and of the pulmonary arteries. The details of the established surgical management for each component of the surgical repair are analysed and described. Over a period of 12years (from 1993 to 2005) 318 consecutive patients with tetralogy of Fallot underwent repair with one hospital death (1/318=0.3% mortality).
- Published
- 2014
19. Ebstein Anomaly in adolescents and young adults
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Andrea Quarti, Sylvain Chauvaud, Chauvaud S., and Quarti A.
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Anterior leaflet ,Tricuspid valve ,medicine.anatomical_structure ,EBSTEIN ANOMALY ,business.industry ,Posterior leaflet ,medicine ,Anatomy ,Young adult ,business ,Tricuspid valve repair Ebstein anomaly - Abstract
Firstly described by W. Ebstein in 1866, the Ebstein anomaly (EA) is composed of a wide spectrum of malformations, so that every valve taken into consideration is a unique valve. EA is rare, accounting for approximately 1-5 cases every 200,000 live births and representing less than 1 % of all CHD, but is the most frequent congenital lesion of the tricuspid valve (TV). Natural history of patients with EA is poor. Early presentation in life is associated with high percentage of mortality, while patients who survived the neonatal period have a limited life expectancy. Deaths usually occur for arrhythmic events and heart failure. From the embryological point of view, the anomaly is related to a failure of delamination of the TV leaflets which reflects with a characteristic pattern of morphological anomalies involving the TV and the right ventricle (RV). This cohort of abnormalities could be associated with rhythm disturbances and other cardiac defects. The disease may have a clinical neonatal presentation which corresponds to a severe RV and TV dysfunction or may present later in life, concurrently with an increasing degree of TV regurgitation and RV dilatation. Since the pioneer period of cardiac surgery, many techniques have been described to address the TV and RV anomalies including TV replacement which is still an option, despite reconstructive techniques being now preferred due to the improvement of the early and long-term results. The aim of the repairing techniques is to restore a normal tricuspid valve function, to preserve the right ventricular contractility, and to decrease the risk of rhythm disturbances. Results are associated with the severity of the disease, the surgeon experience, and the perioperative care of the patient.
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- 2014
20. Bilateral pulmonary artery banding
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Alessandra Oggianu, Marco Pozzi, Andrea Quarti, Massimo Colaneri, Alessandra Baldinelli, Quarti A., Colaneri M., Baldinelli A., Oggianu A., and Pozzi M.
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medicine.medical_specialty ,palliation ,business.industry ,pulmonary arterie ,hypoplastic left heart syndrome ,General Medicine ,medicine.disease ,Hypoplastic left heart syndrome ,Pulmonary artery banding ,stents ,Internal medicine ,Pediatrics, Perinatology and Child Health ,medicine ,Cardiology ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Abstract
No abstract available
- Published
- 2013
21. Valve leaflet reconstruction in pediatrics with extracellular matrix patch
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Andrea, Quarti, Stefania, Nardone, Massimo, Colaneri, Gaetano, Santoro, and Marco, Pozzi
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Child Development ,Postoperative Complications ,Echocardiography ,Transplantation, Heterologous ,Heart Valve Diseases ,Humans ,Child ,Heart Valves ,Cardiac Valve Annuloplasty ,Extracellular Matrix ,Monitoring, Physiologic ,Time - Published
- 2012
22. Brachial arteriovenous fistula in patients with cavopulmonary connection and poor ventricular function: a bridge to Fontan operation
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Marco Pozzi, P Colonna, Elli Soura, Alessandra Oggianu, Andrea Quarti, Massimo Colaneri, Quarti A., Oggianu A., Soura E., Colaneri M., Colonna P.L., and Pozzi M.
- Subjects
Pulmonary and Respiratory Medicine ,Heart Defects, Congenital ,Male ,medicine.medical_specialty ,Adolescent ,Fistula ,Blood viscosity ,Arteriovenous fistula ,Fontan Procedure ,Arteriovenous Shunt, Surgical ,Internal medicine ,medicine.artery ,medicine ,Ventricular Dysfunction ,Humans ,cardiovascular diseases ,Brachial artery ,Child ,Oxygen saturation (medicine) ,Ejection fraction ,business.industry ,Infant, Newborn ,medicine.disease ,Surgery ,Preload ,Bridge (graph theory) ,Child, Preschool ,Cardiology ,cardiovascular system ,Cardiology and Cardiovascular Medicine ,business ,Human - Abstract
Objective: Augmentation of pulmonary blood flow is the only surgical treatment to reduce symptoms of cyanosis in patients with cavopulmonary connection unsuitable for Fontan operation. Brachial arteriovenous fistula is a good option to increase pulmonary blood flow. In this report, we analyze its possible consequences on ventricular function. Methods: Six patients considered unsuitable for a Fontan completion because of poor ventricular function underwent brachial arteriovenous fistula. The fistula was performed with the interposition of a 4-mm gore-tex conduit between the brachial vein and the brachial artery. Results: The mean oxygen saturation increased from 76.8 ± 1.9% to 84.1 ± 1.4% (p < 0.01); hemoglobin and hematocrit decreased from 21.13 ± 0.7 g/dL to 18.12 ± 0.5 g/dL (p < 0.01) and from 63.3 ± 2.7% to 54.2 ± 0.7% (p < 0.01), respectively. Mean ejection fraction and shortening fraction increased from 38.6 ± 1.5% to 49.5 ± 2.3% (p < 0.01) and from 23.3 ± 1.8% to 28.8 ± 1.3% (p < 0.01), respectively. A Fontan completion and takedown of the fistula was then accomplished, within six years, with no mortality or major complications. At a mean follow-up of 15 months, all six patients are clinically in good condition. Conclusion: In patients with a cavopulmonary connection and poor ventricular function, the brachial arteriovenous fistula may play a role in increasing oxygen saturation, optimizing ventricular preload, and reducing blood viscosity and pulmonary arteriovenous malformations. This approach might represent an intermediate step to rescue patients previously considered unsuitable or at high risk for Fontan operation. © 2011 Wiley Periodicals, Inc.
- Published
- 2011
23. Heparin infusion and haemorrhagic complications in patients treated with modified Blalock-Taussig shunt: significance of a nurse and medical audit
- Author
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Marco Pozzi, Andrea Quarti, Gabriella Bernabucci, Simona Marchetti, Alessandra Oggianu, Bernabucci G., Marchetti S., Quarti A., Oggianu A., and Pozzi M.
- Subjects
Adult ,Male ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Antiplatelet drug ,medicine.medical_treatment ,audit ,Hemorrhage ,Risk Assessment ,Drug Administration Schedule ,Cohort Studies ,Infusion therapy ,medicine ,Humans ,Infusions, Intravenous ,Blalock-Taussig Procedure ,Retrospective Studies ,Advanced and Specialized Nursing ,Cyanosis ,Postoperative Care ,Medical Audit ,Dose-Response Relationship, Drug ,anti-thrombin ,business.industry ,Heparin ,Incidence ,Antithrombin ,Nursing Audit ,Anticoagulants ,Retrospective cohort study ,Middle Aged ,bleeding ,shunt ,Surgery ,Shunt (medical) ,Medical–Surgical Nursing ,Treatment Outcome ,Cohort ,Female ,haemorrhage ,business ,Cardiology and Cardiovascular Medicine ,medicine.drug ,Cohort study ,Follow-Up Studies - Abstract
The modified Blalock-Taussig shunt is a surgical option in cyanotic patients. In our Institute heparin infusion therapy in the early postoperative period is used to reduce the risk of shunt thrombosis. This may produce haemorrhagic complications. Herein we describe the effect of a multidisciplinary audit to reduce the risk of haemorrhagic complications. Between January 2005 and December 2009, 49 patients received a modified Blalock-Taussig shunt and anticoagulation therapy until the second administration of an antiplatelet drug. Four patients (8.1%) experienced a haemorrhagic event. A multidisciplinary audit was organized to analyze our anticoagulation protocol. The cohort of patients was divided into group 1 and 2: patients without and with haemorrhagic events respectively. Group 2 was characterized by a low level of anticoagulation in the first postoperative day and received a dose of antithrombin III and an increase in heparin infusion. The result was excessive anticoagulation, evidenced by a significant increase in the aPTT from 44 to 138 sec (in Group 1: from 88 to 54 sec). Retrospectively the nursing staff found that these patients presented clinical signs heralding more significant bleeding. The clinical audit depicted a difference between the two groups. Group 2 was initially characterized by heparin resistance and was consequently treated. The nursing staff found that retrospectively there were clinical signs heralding bleeding and created a risk score. Finally the analysis of this data produced a change in the institutional anticoagulation protocol and created a medical and nursing combined protocol for postoperative anticoagulation screening. Since then, the haemorrhagic complications have been reduced significantly.
- Published
- 2011
24. Preliminary experience in the use of an extracellular matrix to repair congenital heart diseases
- Author
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Marco Pozzi, Gaetano Santoro, Andrea Quarti, Stefania Nardone, Massimo Colaneri, Quarti A., Nardone S., Colaneri M., Santoro G., and Pozzi M.
- Subjects
Pulmonary and Respiratory Medicine ,Aortic arch ,Adult ,Heart Defects, Congenital ,medicine.medical_specialty ,Time Factors ,Adolescent ,Time Factor ,Swine ,Biocompatible Materials ,Postoperative Complications ,Internal medicine ,medicine.artery ,Ascending aorta ,Medicine ,Ventricular outflow tract ,Animals ,Humans ,Cardiac Surgical Procedures ,Child ,Valve repair ,Biocompatible Material ,Aorta ,Wound Healing ,business.industry ,Animal ,Congenital heart defect ,Vascular patch ,Infant, Newborn ,Infant ,Extracellular matrix ,medicine.disease ,Surgery ,Cardiac surgery ,medicine.anatomical_structure ,Treatment Outcome ,Italy ,Pulmonary valve ,Child, Preschool ,Pulmonary artery ,Cardiology ,cardiovascular system ,Postoperative Complication ,Cardiology and Cardiovascular Medicine ,business ,Calcification ,Human - Abstract
Congenital heart diseases are corrected early in life, so the surgical procedure has to maintain the maximum potential for growth. The quest for the ideal material for cardiac tissue repair is still ongoing. Here, we describe our preliminary experience with an extracellular matrix for cardiac and vascular tissue repair. Between August 2009 and April 2011, 26 patients underwent cardiac surgery using the CorMatrix patch for vascular repair (10 pulmonary artery, four ascending aorta, three aortic arch and one right ventricular outflow tract) or for valve reconstruction (five aortic, two tricuspid, one mitral and one pulmonary valve); in four cases, the repair was associated with pericardial closure using the same patch. There were no deaths, and at a mean follow-up of 13.2months, there was no evidence of patch-related complications either in the vascular position or when used for valve repair. The ideal material for cardiac tissue repair should be haemostatic and resistant to tearing and calcification, and possibly one that will not induce an inflammatory cascade. In the last 25months, we used an extracellular matrix for cardiac and vascular tissue repair. The patch is advocated to induce the patient's own tissue regeneration. The early results are encouraging, but a longer follow-up is needed to understand the real potential of this material. © 2011 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.
- Published
- 2011
25. Pericardiectomy for Pleuropericardial Effusion Complicating Bacterial Pneumonia
- Author
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Elli Soura, Fernando Maria de Benedictis, Marco Pozzi, Andrea Quarti, Quarti A., De Benedictis F.M., Soura E., and Pozzi M.
- Subjects
Pediatrics ,medicine.medical_specialty ,Medical treatment ,business.industry ,medicine.medical_treatment ,lcsh:R ,Bacterial pneumonia ,lcsh:Medicine ,Case Report ,General Medicine ,medicine.disease ,Pericardial effusion ,Surgery ,Bacterial pneumonia Pericardiectomy ,Effusion ,Refractory ,medicine ,Pericardiectomy ,Complication ,business - Abstract
Severe pericardial effusion is a rare complication of bacterial pneumonia and it usually disappears under medical treatment. Herein we report a case of a girl with a congenital immunodeficient syndrome and bacterial pneumonia, who developed recurrent and life-threatening pericardial effusion refractory to medical treatment. She was finally treated with pericardiectomy. Copyright © 2010 Andrea Quarti et al.
- Published
- 2010
26. Valve repair in congenital aortic valve abnormalities
- Author
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Marco Pozzi, Alessandra Baldinelli, P Colonna, Andrea Quarti, Massimo Colaneri, Alessandra Oggianu, Pozzi M., Quarti A., Colaneri M., Oggianu A., Baldinelli A., and Colonna P.L.
- Subjects
Adult ,Male ,Pulmonary and Respiratory Medicine ,Aortic valve ,medicine.medical_specialty ,Time Factors ,Adolescent ,Aortic Valve Insufficiency ,Regurgitation (circulation) ,Severity of Illness Index ,Ventricular Function, Left ,Young Adult ,Congenital ,Aortic valve repair ,medicine ,Humans ,Ventricular outflow tract ,Cardiac Surgical Procedures ,Child ,Valve repair ,Retrospective Studies ,business.industry ,Infant ,Aortic valve disorder ,Aortic Valve Stenosis ,medicine.disease ,Surgery ,Stenosis ,Treatment Outcome ,medicine.anatomical_structure ,Child, Preschool ,Aortic valve stenosis ,Ventricular pressure ,cardiovascular system ,Female ,Cardiology and Cardiovascular Medicine ,business ,Echocardiography, Transesophageal - Abstract
Many surgical techniques have been described either to repair and to replace the aortic valve. Among the paediatric population the potential for growth has to be preserved and valve reconstruction is therefore of great importance. In the last two years 25 consecutive patients, mean age 8.6 years, with aortic valve disease, underwent aortic valve repair for aortic regurgitation (AR) (10 patients), aortic valve stenosis (5 patients) or mixed lesion (10 patients). None of the patients died neither during hospitalization nor at follow-up (median 9.25 months). In the aortic stenosis (AS) group, one patient required reoperation (re-repair). None of the patients in the AR group developed more than mild AS and mild AR during follow-up. Nine out of 10 patients of the mixed lesion group had no or trivial AR at the follow-up. Left ventricular dimension decreased in all patients after repair. With a better understanding of the causes of AS or AR and the adoption of different techniques, often used in multiple association, we believe that aortic valve repair can be achieved in most patients with a normal left ventricular outflow tract. © 2010 Published by European Association for Cardio-Thoracic Surgery.
- Published
- 2010
27. Pulmonary Artery Banding: When Is the Use of a Telemetrically Adjustable Device Indicated?
- Author
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Marco Pozzi, Andrea Quarti, Alessandra Baldinelli, Massimo Colaneri, Alessandro D'Alfonso, D'alfonso A., Quarti A., Colaneri M., Baldinelli A., and Pozzi M.
- Subjects
medicine.medical_specialty ,business.industry ,congenital heart surgery ,pulmonary banding ,General Medicine ,Intensive care unit ,congenital heart disease ,Intracardiac injection ,Surgery ,law.invention ,Pulmonary artery banding ,Pulmonary artery debanding ,palliative ,law ,medicine.artery ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Pulmonary artery ,medicine ,Major complication ,Cardiology and Cardiovascular Medicine ,business ,Resource utilization ,Postoperative ventilation - Abstract
Proponents of a telemetrically adjustable pulmonary artery band (PAB) device have cited simplified postoperative management and shortened length of stay as advantages associated with that technology. This report concerns a recent experience with both conventional pulmonary artery banding (conv-PAB) and the telemetrically adjustable PAB FloWatch (FW-PAB). From January 2005 through December 2008, 19 consecutive infants underwent either conv-PAB (8 patients, mean age 3.5 months, mean weight 4.1 kg) or FW-PAB (11 patients, mean age 2.6 months, mean weight 3.1 kg). Indications for PAB were left ventricular retraining (1 patient in FW-PAB), palliation prior to biventricular repair (7 patients in conv-PAB and 10 in FW-PAB group), and staged univentricular repair (1 patient in conv-PAB). In-hospital mortality was 0%. In the FW-PAB group, 1 FloWatch device was removed because of hemodynamic compromise related to the bulk of the device. There were no major complications in the conv-PAB group and no differences between groups with respect to postoperative ventilation time or length of stay in the intensive care unit or in hospital. In the FW-PAB group, a mean of 3.1 ± 1.7 regulations per patient were undertaken. Of the regulations, 85% (29/34) were adjustments to tighten the device, and 15% (5/34) were to loosen it. During follow-up, 8 patients underwent intracardiac repair and pulmonary artery debanding: 4 in the conv-PAB group and 4 in the FW-PAB group. The course of patients in both groups after PAB were similar. Major differences in length of stay and resource utilization were not apparent. © 2010, SAGE Publications. All rights reserved.
- Published
- 2010
28. Edge-to-edge technique: is it also useful in children?
- Author
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Alessandro D'Alfonso, Alessandra Baldinelli, Marco Pozzi, Massimo Colaneri, Maria Grazia Bettuzzi, Roberto Ricciotti, Andrea Quarti, Quarti A., DAlfonso A., Colaneri M., Baldinelli A., Ricciotti R., Bettuzzi M.G., and Pozzi M.
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Edge (geometry) ,Severity of Illness Index ,Congenital ,medicine ,Humans ,Child ,Mitral regurgitation ,Ultrasonography ,Heart Valve Prosthesis Implantation ,Mitral Valve Prolapse ,business.industry ,Incidence (epidemiology) ,Anticoagulants ,Mitral Valve Insufficiency ,General Medicine ,medicine.disease ,Treatment Outcome ,Paediatric ,Child, Preschool ,Mitral Valve ,Female ,Radiology ,Warfarin ,Cardiology and Cardiovascular Medicine ,business ,Mitral valve regurgitation ,Mitral valve repair - Abstract
Objective: Mitral valve prolapse is a rare condition and represents a challenge for cardiac surgeons. Many techniques have been described to treat the wide spectrum of abnormalities causing mitral valve regurgitation but the low incidence of these abnormalities is the cause of the relatively poor experience of many institutions. Methods: From April 2005 to September 2006, five patients underwent isolated mitral valve repair with the edge-to-edge technique for anterior or bileaflet prolapse. Three patients also had a Gore-Tex strip to reinforce the posterior annulus, whereas two had a 26-size soft incomplete ring annuloplasty. Results: There was no death and none of the patients required reoperation. None of the patients had mitral regurgitation more than 1+ at a mean follow-up of 30 months. None of the patients had mitral stenosis or any valve-related event. Conclusion: The edge-to-edge technique is a well tolerated and useful technique for the anterior or bileaflet prolapse of the mitral valve. Although many techniques have been described with good results, in many anatomical settings and in small patients, edge-to-edge is a good option and might not interfere with the growth of the valve. Early results are encouraging but a longer follow-up is needed to evaluate the long-term prognosis. © 2009 Italian Federation of Cardiology.
- Published
- 2009
29. Reimplantation of an anomalous coronary artery arising from the pulmonary artery
- Author
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Alessandro D'Alfonso, Marco Pozzi, Andrea Quarti, Massimo Colaneri, Maria Grazia Bettuzzi, Alessandra Baldinelli, Quarti, Andrea, D'Alfonso, Alessandro, Colaneri, Massimo, Baldinelli, Alessandra, Bettuzzi, Maria Grazia, and Pozzi, Marco
- Subjects
medicine.medical_specialty ,Aorta ,Pericardial patch ,business.industry ,lcsh:R ,lcsh:Medicine ,Case Report ,General Medicine ,Surgery ,ALCAPA Reimplantation ,Left coronary artery ,medicine.artery ,Internal medicine ,Anomalous coronary artery ,Pulmonary artery ,Cardiology ,Medicine ,business - Abstract
A case of anomalous origin of the left coronary artery from the pulmonary artery in a patient with the origin of the coronary opposite to the aorta is reported. Between many surgical options we conclude to reestablish a double coronary system reconnecting the coronary through a conduit created with a pulmonary wall baffle and an autologous pericardial patch.
- Published
- 2009
30. Aortic dilatation in patients with bicuspid aortic valve
- Author
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Andrea Quarti, P Colonna, Gian Piero Perna, Epifanio Molini, Stefano Nistri, Moreno Cecconi, Marcello Manfrin, Cecconi M., Nistri S., Quarti A., Manfrin M., Colonna P.L., Molini E., and Perna G.P.
- Subjects
Aortic valve ,Aortic dilatation ,Heart Defects, Congenital ,medicine.medical_specialty ,Bicuspid aortic valve ,Aortic Diseases ,Heart Valve Diseases ,Aorta, Thoracic ,Dissection (medical) ,Aneurysm ,medicine.artery ,Internal medicine ,Ascending aorta ,Prevalence ,Medicine ,Thoracic aorta ,Humans ,Aortic rupture ,Child ,Aorta ,business.industry ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,Aortic Valve ,Cardiology ,cardiovascular system ,Cardiology and Cardiovascular Medicine ,business ,Aortic surgery ,Dilatation, Pathologic - Abstract
The association of a bicuspid aortic valve (BAV) with abnormalities of the proximal thoracic aorta, including dilatation, aneurysm and dissection, has been previously described, leading to the hypothesis of a common underlying developmental defect involving the aortic valve and the aortic wall. Consequently, any patient with BAV should receive a careful assessment not only of the valve function, but also of the aortic root and the ascending aorta. Dilatation of the proximal thoracic aorta is a common finding in patients with BAV and is believed to be related to aortic rupture and dissection. Because progressive dilatation can occur, careful long-term surveillance of the aortic dimensions is required. Prophylactic surgical repair of the dilated aorta should be recommended more aggressively for patients with BAV than for those with a tricuspid aortic valve. However, the optimal timing of aortic surgery in BAV patients remains uncertain because of the limited data available on the natural history of asymptomatic aortic dilatation. © 2006 Italian Federation of Cardiology.
- Published
- 2006
31. Left superior vena cava draining into the left atrium, associated with partial anomalous pulmonary venous connection: surgical correction
- Author
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Marco Di Eusanio, Michele Danilo Pierri, Andrea Quarti, Giuseppe Di Eusanio, Quarti A, Di Eusanio M, Pierri MD, and Di Eusanio G
- Subjects
Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Vena Cava, Superior ,Left atrium ,Anastomosis ,Heart Septal Defects, Atrial ,Internal medicine ,medicine ,Humans ,Heart Atria ,Persistent left superior vena cava ,cardiovascular diseases ,Left superior vena cava ,Heart septal defect ,business.industry ,Anastomosis, Surgical ,Central venous pressure ,Infant ,medicine.disease ,Shunt (medical) ,medicine.anatomical_structure ,Pulmonary Veins ,Cardiology ,cardiovascular system ,CONGENITAL HEART DISEASE ,Surgery ,Respiratory System Abnormalities ,Cardiology and Cardiovascular Medicine ,business ,Venous return curve - Abstract
A persistent left superior vena cava draining into the left atrium may produce a symptomatic right-to-left shunt. Although intra-atrial rerouting techniques, in patients with no connecting vein, have proved to be reliable and successful, in many cases the extracardiac repair is preferable. We report a case of a 5-month-old patient with a not connected left superior vena cava draining into the left atrium, associated with atrial septal defect and partial anomalous pulmonary venous connection. The correction has been achieved by rerouting the pulmonary venous return into the left atrium and by transposition of the left vena cava on the right appendage.
- Published
- 2005
32. Cannulation of the brachiocephalic trunk during surgery of the thoracic aorta: a simplified technique for antegrade cerebral perfusion
- Author
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Andrea Quarti, Michele Danilo Pierri, Giuseppe Di Eusanio, Marco Di Eusanio, Di Eusanio M, Quarti A, Pierri MD, and Di Eusanio G
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Catheterization, Central Venous ,Heart disease ,Aorta, Thoracic ,AORTA ,law.invention ,law ,medicine.artery ,Internal medicine ,Brachiocephalic artery ,medicine ,Cardiopulmonary bypass ,Thoracic aorta ,Humans ,Cerebral perfusion pressure ,Brachiocephalic Trunk ,Aorta ,Cardiopulmonary Bypass ,Intraoperative Care ,business.industry ,General Medicine ,medicine.disease ,Trunk ,Surgery ,Perfusion ,Cerebrovascular Circulation ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Here we present our simplified technique of cannulation of the brachiocephalic trunk for cardiopulmonary bypass and antegrade cerebral perfusion institution.
- Published
- 2004
33. Totally endoscopic atrial septal defect closure with a robotic system: experience with seven cases
- Author
-
Lucia, Torracca, Gennaro, Ismeno, Andrea, Quarti, and Ottavio, Alfieri
- Subjects
Adult ,Male ,Treatment Outcome ,Thoracic Surgery, Video-Assisted ,Humans ,Minimally Invasive Surgical Procedures ,Female ,Robotics ,Heart Septal Defects, Atrial - Abstract
The development of minimally invasive cardiac surgery has shown good clinical results with shorter recovery time and better cosmetic results. The introduction of the robotic systems can further reduce the surgical trauma and improve the surgical dexterity. We report seven cases of complete closed chest atrial septal defect closure using the "da Vinci" Surgical System (Intuitive Surgical, Mountain View, CA).Following peripheral cannulation for cardiopulmonary bypass (CPB), aortic occlusion and cardioplegia delivery, five patients with atrial septal defect (ASD) and two patients with patent forame ovale (PFO) with atrial septal aneurysm (ASA) were successfully treated using the robotic system. Two robotic arms and an endoscopic camera were inserted through ports in the right hemithorax and an accessory port was placed for blood suction and ancillary instruments insertion. The defect closure was carried out with interrupted stitches in one patient and with a continuous suture in the others.Mean cardiopulmonary bypass and cross clamp time were 101.8 +/- 39.6 and 63.4 +/- 21.9 minutes respectively. Extubation was carried out within the seventh postoperative hour. All patients returned to normal lifestyle in one week.Complete closed chest ASD closure can be carried out using robotic technique with rapid postoperative recovery and excellent cosmetic result.
- Published
- 2002
34. Mitral Valve Damage After an Aortic Balloon Valvuloplasty in an Infant
- Author
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Marco Pozzi, Filippo Capestro, Andrea Quarti, Capestro F., Quarti A., and Pozzi M.
- Subjects
Balloon valvuloplasty ,medicine.medical_specialty ,Aortography ,Aortic valve stenosi ,Catheterization ,Diagnosis, Differential ,Internal medicine ,Mitral valve ,medicine ,Humans ,cardiovascular diseases ,Mitral regurgitation ,Surgical repair ,medicine.diagnostic_test ,Mitral valve damage ,business.industry ,Mitral Valve Insufficiency ,Aortic Valve Stenosis ,Cardiac surgery ,Vascular surgery ,medicine.disease ,medicine.anatomical_structure ,Echocardiography ,Child, Preschool ,Aortic valve stenosis ,Pediatrics, Perinatology and Child Health ,cardiovascular system ,Cardiology ,Mitral Valve ,Cardiology and Cardiovascular Medicine ,business - Abstract
The case of a 2-year-old infant admitted to our Institution with a diagnosis of severe aortic valve stenosis is presented. After a balloon valvuloplasty with no results in terms of gradient reduction, an echocardiogram showed a moderate mitral regurgitation. The patient underwent surgical repair of both the aortic and mitral valves. Inspection of the mitral valve showed a 5-mm hole in the posterior leaflet at the P2 scallop. Probably, the dilation tore a secondary cord, pulling away a piece of the leaflet. A quadrangular resection was performed with good results. © Springer Science+Business Media, LLC 2011.
- Published
- 2011
35. Cardiac echinococcus complicated by ventricular tachycardia
- Author
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Francesco Violante, Ottavio Alfieri, Abele Ajello, Marcello Marcì, Antonino Battaglia, Andrea Quarti, Andrea Pizzuto, Francesca Finazzo, Marci M., Ajello A., Finazzo F., Violante F., Pizzuto A., Battaglia A., Quarti A., Alfieri O., Marci, M, Ajello, A, Finazzo, F, Violante, F, Pizzuto, A, Battaglia, A, Quarti, A, and Alfieri, Ottavio
- Subjects
Adult ,Diagnostic Imaging ,Male ,Cardiac echinococcosi ,medicine.medical_specialty ,Ventricular tachycardia ,Sensitivity and Specificity ,Two-dimensional echocardiography ,Echinococcosis ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,biology ,medicine.diagnostic_test ,business.industry ,Two dimensional echocardiography ,Magnetic resonance imaging ,biology.organism_classification ,medicine.disease ,Magnetic Resonance Imaging ,Echinococcus ,Echocardiography ,Tachycardia, Ventricular ,Cardiology ,cardiovascular system ,Radiology ,Tomography ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business - Abstract
Echinococcosis is a parasitic disease that usually involves lungs and liver. Occasionally, it localizes in the heart (less than 2% of cases). We present a case of an adult patient with cardiac echinococcosis complicated by ventricular tachycardia. The diagnosis, based on transthoracic two-dimensional echocardiography, magnetic resonance imaging (MRI), and computerized tomography (CT), was confirmed by surgery.
- Published
- 2001
36. Late Cardiac Perforation After Transcatheter Closure of Patent Foramen Ovale
- Author
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Moreno Cecconi, Gian Piero Perna, Sante Bucari, Andrea Giovagnoni, Carlo Costantini, Andrea Quarti, Fabio Bianchini, Cecconi M., Quarti A., Bianchini F., Bucari S., Costantini C., Giovagnoni A., and Perna G.P.
- Subjects
Male ,Pulmonary and Respiratory Medicine ,Cardiac Catheterization ,Chest Pain ,medicine.medical_specialty ,Aortic root ,Perforation (oil well) ,Postoperative Hemorrhage ,digestive system ,Heart Septal Defects, Atrial ,Brain Ischemia ,Prosthesis Implantation ,Postoperative Complications ,Left atrial wall ,stomatognathic system ,Recurrence ,Internal medicine ,Cardiac Perforation ,medicine ,Humans ,Heart Atria ,Aorta ,cardiac perforation ASD ,Aged ,Heart septal defect ,business.industry ,digestive, oral, and skin physiology ,Equipment Design ,Prostheses and Implants ,medicine.disease ,Heart Injuries ,Intracranial Embolism ,cardiovascular system ,Patent foramen ovale ,Cardiology ,Surgery ,Emergencies ,Cardiology and Cardiovascular Medicine ,Complication ,business - Abstract
Cardiac perforation after transcatheter closure of a patent foramen ovale is a very rare complication. We report a case of left atrial wall perforation and aortic root erosion occurring 16 months after implantation of an Amplatzer patent foramen ovale occluder that required emergent surgery. © 2006 The Society of Thoracic Surgeons.
- Published
- 2006
37. The Green Era of Food Packaging: General Considerations and New Trends
- Author
-
Enrico Maurizzi, Francesco Bigi, Andrea Quartieri, Riccardo De Leo, Luisa Antonella Volpelli, and Andrea Pulvirenti
- Subjects
biopolymers ,antioxidant compounds ,antimicrobial compounds ,essential oils ,nanoparticles ,Organic chemistry ,QD241-441 - Abstract
Recently, academic research and industries have gained awareness about the economic, environmental, and social impacts of conventional plastic packaging and its disposal. This consciousness has oriented efforts towards more sustainable materials such as biopolymers, paving the way for the “green era” of food packaging. This review provides a schematic overview about polymers and blends of them, which are emerging as promising alternatives to conventional plastics. Focus was dedicated to biopolymers from renewable sources and their applications to produce sustainable, active packaging with antimicrobial and antioxidant properties. In particular, the incorporation of plant extracts, food-waste derivatives, and nano-sized materials to produce bio-based active packaging with enhanced technical performances was investigated. According to recent studies, bio-based active packaging enriched with natural-based compounds has the potential to replace petroleum-derived materials. Based on molecular composition, the natural compounds can diversely interact with the native structure of the packaging materials, modulating their barriers, optical and mechanical performances, and conferring them antioxidant and antimicrobial properties. Overall, the recent academic findings could lead to a breakthrough in the field of food packaging, opening the gates to a new generation of packaging solutions which will be sustainable, customised, and green.
- Published
- 2022
- Full Text
- View/download PDF
38. Exploring the Microbial Community of Traditional Sourdoughs to Select Yeasts and Lactic Acid Bacteria
- Author
-
Giovanna Iosca, Luciana De Vero, Maria Gullo, Fabio Licciardello, Andrea Quartieri, and Andrea Pulvirenti
- Subjects
sourdoughs ,starter culture ,sequencing ,General Works - Abstract
Sourdoughs represent an awesome example of ecosystem in which yeasts and lactic acid bacteria (LAB) interact with each other, defining the characteristics of the final product in terms of composition, texture, taste and flavor. Therefore, the identification of dominant yeasts and LAB involved in the fermentation process can lead to the selection of starters with suitable fermentation aptitude and capable of producing desired aromas and/or aromatic precursors. In this work, two sourdoughs samples (A and B) for Panettone production were collected from an artisan bakery. Yeasts and bacteria were isolated at different fermentation steps on selective agar media. A total of 120 isolates were obtained and firstly characterized by conventional microbiological methods. Afterward, genomic DNA was extracted from the cultures, and (GTG)5-PCR fingerprinting analysis was carried out to reduce the redundance among the isolates. Representative yeasts and LAB strains, having a unique profile, were identified by sequencing the D1/D2 domain of the 26S rRNA and the 16S rRNA genes, respectively. The results highlighted the occurrence of Kazachstania humilis and Fructilactobacillus sanfranciscensis in both sourdoughs. Among LAB, also some other strains belonging to Lactobacillus genus were found. Moreover, Saccharomyces cerevisiae and Staphylococcus spp. strains were detected in sample B. In this study, a pool of yeasts and LAB strains for producing starter cultures with specific technological traits for sourdoughs production was obtained.
- Published
- 2020
- Full Text
- View/download PDF
39. Hydrolysis of the Rutinose-Conjugates Flavonoids Rutin and Hesperidin by the Gut Microbiota and Bifidobacteria
- Author
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Alberto Amaretti, Stefano Raimondi, Alan Leonardi, Andrea Quartieri, and Maddalena Rossi
- Subjects
bifidobacterium ,hesperidin ,hesperetin ,rutin ,quercetin ,rutinosides ,polyphenols ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Flavonols and flavanones are polyphenols exerting many healthy biological activities. They are often glycosylated by rutinose, which hampers absorption in the small intestine. Therefore they require the gut microbiota to release the aglycone and enable colonic absorption. The role of the gut microbiota and bifidobacteria in the release of the aglycones from two major rutinosides, hesperidin and rutin, was investigated. In bioconversion experiments, the microbiota removed rutinose from both rutin and hesperidin, even though complete hydrolysis was not obtained. To investigate whether bifidobacteria can participate to the hydrolysis of rutinosides, 33 strains were screened. Rutin was resistant to hydrolysis by all the strains. Among six tested species, mostly Bifidobacterium catenulatum and Bifidobacterium pseudocatenultum were able to hydrolyze hesperidin, by means of a cell-associated activity. This result is in agreement with the presence of a putative α-l-rhamnosidase in the genome of B. pseudocatenulatum, while most of the available genome sequences of bifidobacteria aside from this species do not bear this sequence. Even though B. pseudocatenulatum may contribute to the release of the aglycone from certain rutinose-conjugated polyphenols, such as hesperidin, it remains to be clarified whether this species may exert a role in affecting the bioavailability of the rutinoside in vivo.
- Published
- 2015
- Full Text
- View/download PDF
40. Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall
- Author
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Ines Carloni, Andrea Quarti, Marco Pozzi, Fernando Maria de Benedictis, Stefano Gasparini, Massimo Colaneri, Colaneri M., Quarti A., Pozzi M., Gasparini S., Carloni I., and De Benedictis F.M.
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,Heart disease ,medicine.medical_treatment ,Case Report ,Plastic bronchitis ,Respiratory Mucosa ,Tissue plasminogen activator ,Diagnosis, Differential ,Fontan procedure ,Plastic bronchiti ,Primary ciliary dyskinesia ,Administration, Inhalation ,Bronchoscopy ,medicine ,Humans ,Respiratory system ,Bronchitis ,Respiratory distress ,business.industry ,Nebulizers and Vaporizers ,medicine.disease ,Surgery ,Microscopy, Electron ,Complication ,business ,Follow-Up Studies ,medicine.drug - Abstract
Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely and may cause severe life-threatening respiratory distress. The management of plastic bronchitis is yet not well defined. Early intermittent, self-administered nebulization of tissue plasminogen activator was found to be effective in preventing deterioration of acute respiratory symptoms in a patient with primary ciliary dyskinesia and recurrent cast formation. Further investigation into new therapeutic strategies for this devastating disease is advocated. © 2014 Colaneri et al.; licensee BioMed Central Ltd.
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