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3 results on '"Andreas Häberlin"'

1. Diagnostic and prognostic values of the QRS‐T angle in patients with suspected acute decompensated heart failure

Author

Romy Sweda, Zaid Sabti, Ivo Strebel, Nikola Kozhuharov, Desiree Wussler, Samyut Shrestha, Dayana Flores, Patrick Badertscher, Pedro Lopez‐Ayala, Tobias Zimmermann, Eleni Michou, Danielle M. Gualandro, Andreas Häberlin, Hildegard Tanner, Dagmar I. Keller, Albina Nowak, Otmar Pfister, Tobias Breidthardt, Christian Mueller, and Tobias Reichlin

Subjects
Acute heart failure, Heart failure, Acute dyspnoea, QRS‐T angle, ECG, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Aims The aim of this study was to investigate the diagnostic and prognostic utility of the QRS‐T angle, an electrocardiogram (ECG) marker quantifying depolarization–repolarization heterogeneity, in patients with suspected acute decompensated heart failure (ADHF). Methods and results We prospectively enrolled unselected patients presenting to the emergency department with symptoms suggestive of ADHF. The QRS‐T angle was automatically derived from a standard 12‐lead ECG recorded at presentation. The primary diagnostic endpoint was a final adjudicated diagnosis of ADHF. The primary prognostic endpoint was all‐cause mortality during 2 years of follow‐up. Among the 1915 patients enrolled, those with higher QRS‐T angles were older, were more commonly male, and had a higher rate of co‐morbidities such as arterial hypertension, coronary artery disease, or chronic kidney disease. ADHF was the final adjudicated diagnosis in 1140 (60%) patients. The QRS‐T angle in patients with ADHF was significantly larger than in patients with non‐cardiac causes of dyspnoea {median 110° [inter‐quartile range (IQR) 46–156°] vs. median 33° [IQR 15–57°], P

Published
2020
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2. B-PO02-032 SUCCINATE ACCUMULATION IN ATRIAL CARDIOMYOCYTES INCREASES MITOCHONDRIAL REVERSE ELECTRON FLUX, OXIDATIVE STRESS, AND MIGHT PARTICIPATE TO AF STABILIZATION IN THE SHEEP

Author

Philippe Diolez, Guido Caluori, Valentin Meillet, Sylvain Ploux, Bastien Guillot, Stéphane N. Hatem, Pierre Dos Santos, Emma Abell, Philipp Krisai, Rémi Dubois, Andreas Häberlin, Farid Ichou, Olivier Bernus, Hassan-Adam Mahamat, Pierre Jaïs, Tsukasa Kamakura, Virginie Loyer, Philippe Pasdois, Fanny Vaillant, and Mélèze Hocini

Subjects
business.industry, Electron flux, Physiology (medical), Biophysics, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease_cause, Oxidative stress
Published
2021

3. Is 7-day event triggered ECG recording equivalent to 7-day Holter ECG recording for atrial fibrillation screening?

Author

Manuel Schilling, Jens Seiler, Laurent Roten, Etienne Delacrétaz, Andreas Häberlin, Jürg Fuhrer, Hildegard Tanner, and Nicola Schwick

Subjects
Male, medicine.medical_specialty, Time Factors, Dermatitis, Sensitivity and Specificity, Electrocardiography, Device removal, Internal medicine, Atrial Fibrillation, Medicine, Humans, Mass Screening, Prospective Studies, Event triggered, Device Removal, Paroxysmal AF, Aged, medicine.diagnostic_test, business.industry, Atrial fibrillation, Patient Preference, Signal Processing, Computer-Assisted, Middle Aged, medicine.disease, Ecg monitoring, Skin irritation, Cardiology, Electrocardiography, Ambulatory, Female, Cardiology and Cardiovascular Medicine, business, Holter ecg
Abstract

Prolonged ECG monitoring is standard for atrial fibrillation (AF) screening. This study investigated whether 7-day event triggered (tECG) ECG recording is equivalent to 7-day continuous Holter (cECG) ECG recording for AF screening.Both a cECG (Lifecard CF) and a tECG (R.Test Evolution 3) were simultaneously worn for 7 days by patients with known or suspected paroxysmal AF.In 100 corresponding recordings, median effective duration of monitoring was 165 h (range 10-170 h) for cECG and 137 h (0-169 h) for tECG (p0.001). Median number and total duration of arrhythmias (AF, atrial flutter or atrial tachycardia) of ≥30 s duration recorded by cECG were 10 (1-428) and 1030 min (≤1-10,020), respectively. An arrhythmia was recorded in 42 cECGs (42%) versus 37 tECGs (37%, p=0.56). Triggered ECG failed to record an arrhythmia in cECG positive cases because of interrupted monitoring in four cases and because of recording failure in one case. Sensitivity, specificity, and positive and negative predictive values of tECG therefore were 88%, 100%, 100%, and 92%, respectively. Quantitative cECG analysis required a median of 20 min (3-205 min) and qualitative tECG analysis 4 min (1-20 min; p0.001). Skin irritation was a frequent side effect (42%) resulting in premature removal of devices in 16% of patients.Sensitivity of tECG for AF screening as compared to cECG is lower, mainly because of shorter effective monitoring duration. Qualitative tECG analysis is less time consuming than quantitative cECG analysis. Skin irritation is a frequent side effect and reason for premature device removal.

Published
2012

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