1. Dynamic beamforming for large area scan in array-based photoacoustic microscopy
- Author
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Andreu Descals, Francisco Camarena, Jose M. Benlloch, Juan J. Garcia-Garrigos, A. Cebrecos, and Noé Jiménez
- Subjects
0301 basic medicine ,Beamforming ,Materials science ,Pulsed laser diode ,Phased array ,Photoacoustic imaging in biomedicine ,Large areascan ,01 natural sciences ,law.invention ,010309 optics ,03 medical and health sciences ,Optics ,Photoacoustic microscopy ,law ,0103 physical sciences ,Leverage (statistics) ,Linear probe ,Laser diode ,business.industry ,OR-PAM ,Laser ,030104 developmental biology ,FISICA APLICADA ,Photoacoustic imaging ,business ,Array-based beamforming - Abstract
[EN] We explore the use of a beamforming method intended for large-area scanning in optical-resolution photoacoustic microscopy. It has been evaluated in a experimental setup that comprises a low-cost laser diode and a phase array with a 128-elements linear probe. Three different beamforming strategies are discussed: no-beamforming, static beamforming and dynamic beamforming. The method has been tested in gelatine-based phantoms as well as ex-vivo organs. Results show that, compared with the other two, dynamic beamforming increases up to 15dB and homogenizes signal-to-noise ratio (SNR) along images of roughly 1 cm2. The method and system presented here could be the baseline for more advanced array-based systems that leverage the low-cost laser sources for clinical applications., This research has been supported by the Spanish Ministry of Science, Innovation and Universities through grant Juan de la Cierva - Incorporacion (IJC2018-037897-I), and program Proyectos I+D+i 2019 (PID2019-111436RB-C22). Action co-financed by the European Union through the Programa Operativo del Fondo Europeo de Desarrollo Regional (FEDER) of the Comunitat Valenciana 2014-2020 (IDIFEDER/2018/022). A.C. received financial support from Generalitat Valenciana and Universitat Politecnica de Val ` encia through the grants APOSTD/2018/229 and program PAID-10-19, respectively.
- Published
- 2020
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