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4. Intraarterial Catheter Use Is Associated With Increased Risk of Hospital Onset Bacteremia

Author

Alexandra Kadl, Kyle B. Enfield, and Andrew Barros

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Retrospective cohort study, Critical Care and Intensive Care Medicine, medicine.disease, Catheter, Text mining, Increased risk, Bacteremia, Internal medicine, Intra arterial, Medicine, Cardiology and Cardiovascular Medicine, business
Published
2021
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5. Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO):a randomised controlled trial

Author

Wesley H. Self, Uriel Sandkovsky, Cavan S. Reilly, David M. Vock, Robert L. Gottlieb, Michael Mack, Kevin Golden, Emma Dishner, Andrew Vekstein, Emily R. Ko, Tatyana Der, John Franzone, Eyad Almasri, Mohamed Fayed, Michael R. Filbin, Kathryn A. Hibbert, Todd W. Rice, Jonathan D. Casey, J. Awori Hayanga, Vinay Badhwar, Bradley G. Leshnower, Milad Sharifpour, Kirk U. Knowlton, Ithan D. Peltan, Elizieta Bakowska, Justyna Kowalska, Michael E. Bowdish, Jeffrey M. Sturek, Angela J. Rogers, D. Clark Files, Jarrod M. Mosier, Michelle N. Gong, David J. Douin, R. Duncan Hite, Barbara W. Trautner, Mamta K. Jain, Edward M. Gardner, Akram Khan, Jens-Ulrik Jensen, Michael A. Matthay, Adit A. Ginde, Samuel M. Brown, Elizabeth S. Higgs, Sarah Pett, Amy C. Weintrob, Christina C. Chang, Daniel D. Murrary, Huldrych F. Günthard, Ellen Moquete, Greg Grandits, Nicole Engen, Birgit Grund, Shweta Sharma, Huyen Cao, Rajesh Gupta, Suzette Osei, David Margolis, Qing Zhu, Mark N. Polizzotto, Abdel G. Babiker, Victoria J. Davey, Virginia Kan, B. Taylor Thompson, Annetine C. Gelijns, James D. Neaton, H. Clifford Lane, Jens D. Jundgren, John Tierney, Kevin Barrett, Betsey R. Herpin, Mary C. Smolskis, Susan E. Voge, Laura A. McNay, Kelly Cahill, Page Crew, Matthew Kirchoff, Ratna Sardana, Sharon Segal Raim, Joseph Chiu, Lisa Hensley, Josua Lorenzo, Rebecca Mock, Katy Shaw-Saliba, Judith Zuckerman, Stacey J. Adam, Judy Currier, Sarah Read, Eric Hughes, Laura Amos, Amy Carlsen, Anita Carter, Bionca Davis, Eileen Denning, Alain DuChene, Merrie Harrison, Payton Kaiser, Joseph Koopmeiners, Sue Meger, Thomas Murray, Kien Quan, Siu Fun Quan, Greg Thompson, Jamie Walski, Deborah Wentworth, Alan J. Moskowitz, Emilia Bagiella, Karen O'Sullivan, Mary E. Marks, Evan Accardi, Emily Kinzel, Gabriela Bedoya, Lopa Gupta, Jessica R. Overbey, Maria L. Padillia, Milerva Santos, Marc A. Gillinov, Marissa A. Miller, Wendy C. Taddei-Peters, Kathleen Fenton, Mezgebe Berhe, Clinton Haley, Christopher Bettacchi, Erin Duhaime, Madison Ryan, Sarah Burris, Felecia Jones, Samantha Villa, Samantha Want, Raven Robert, Tanquinisha Coleman, Laura Clariday, Rebecca Baker, Marian Hurutado-Rodriguez, Nazia Iram, Michelle Fresnedo, Allyson Davis, Kiara Leonard, Noelia Ramierez, Jon Thammavong, Krizia Duque, Emma Turner, Tammy Fisher, Dianna Robinson, Desirae Ransom, Erica Lusk, Aaron Killian, Adriana Palacious, Edilia Solis, Janet Jerrow, Matthew Watts, Heather Whitacre, Elizabeth Cothran, Peter K. Smith, Christina E. Barkauskas, Grace R. Dreyer, Marie Witte, Nilima Mosaly, Ahmad Mourad, Thomas L. Holland, Kathleen Lane, Andrew Bouffler, Lauren M. McGowan, Marry Motta, Gregory Tipton, Ben Stallings, Gennifer Stout, Beth McLendon-Arvik, Beth A. Hollister, Dana M. Giangiacomo, Sunil Sharma, Brian Pappers, Paul McCarthy, Troy Krupica, Arif Sarwari, Rebecca Reece, Lisa Fornaresio, Chad Glaze, Raquel Evans, Katarina Preamble, Lisa Giblin Sutton, Sabrina Buterbaugh, Elizabeth Berry Bartolo, Roger Williams, Robin Bunner, William Bender, Jeffrey Miller, Kim T. Baio, Mary K. McBride, Michele Fielding, Sonya Mathewson, Kristina Porte, Missy Maton, Chari Ponder, Elizabeth Haley, Christine Spainhour, Susan Rogers, Derrick Tyler, Noah Wald-Dickler, Douglass Hutcheon, Amytis Towfighi, May M. Lee, Meghan R. Lewis, Brad Spellberg, Linda Sher, Aniket Sharma, Anna P. Olds, Chris Justino, Edward Lozano, Chris Romero, Janet Leong, Valentina Rodina, Tammie Possemato, Jose Escobar, Charlene Chiu, Kevin Weissman, Andrew Barros, Kyle B. Enfield, Alexandra Kadl, China J. Green, Rachel M. Simon, Ashley Fox, Kara Thornton, Patrick E. Parrino, Stephen Spindel, Aditya Bansal, Katherine Baumgarten, Jonathan Hand, Derek Vonderhaar, Bobby Nossaman, Sylvia Laudun, DeAnna Ames, Shane Broussard, Nilmo Hernandez, Geralyn Isaac, Huan Dinh, Yiling Zheng, Sonny Tran, Hunter McDaniel, Nicolle Crovetto, Leslie Miller, Beth Schelle, Sherry McLean, Howard R. Rothbaum, Michael S. Alvarez, Shivam P. Kalan, Heather H. Germann, Jennifer Hendershot, Karen Maroney, Karen Herring, Sharri Cook, Pam Paul, Ronson J. Madathil, Joseph Rabin, Andrea Levine, Kapil Saharia, Ali Tabatabai, Christine Lau, James S. Gammie, Maya-Loren Peguero, Kimberley McKernan, Matthew Audette, Emily Fleischmann, Freshta Akbari, Maia Lee, Myounghee Lee, Andrew Chi, Hanna Salehi, Alan Pariser, Phuong Tran Nguyen, Jessica Moore, Adrienne Gee, Shelika Vincent, Richard A. Zuckerman, Alexander Iribarne, Sara Metzler, Samantha Shipman, Taylor Caccia, Haley Johnson, Crystallee Newton, Doug Parr, Vicente Rodriguez, Gordon Bokhart, Sharon M. Eichman, Crystal North, Cathryn Oldmixon, Nancy Ringwood, Laura Fitzgerald, Haley D. Morin, Ariela Muzikansky, Richard Morse, Roy G. Brower, Lora A. Reineck, Neil R. Aggarwal, Karen Bienstock, Peter Hou, Jay Steingrub, Mark A. Tidswell, Lori-Ann Kozikowski, Cynthia Kardos, Leslie DeSouza, Sherell Thornton-Thompson, Daniel Talmor, Nathan Shapiro, Valerie Banner-Goodspeed, Katherine L. Boyle, Sharon Hayes, Alan E. Jones, James Galbraith, Utsav Nandi, Rebekah K. Peacock, Blair Alden Parry, Justin D. Margolin, Kelsey Brait, Caroline Beakes, Kirsten N. Kangelaris, Kimberly J. Yee, Kimia Ashktorab, Alejandra E. Jauregui, Hanjing Zhuo, Gregory Hendey, Kinsley A. Hubel, Alyssa R. Hughes, Rebekah L. Garcia, Jennifer G. Wilson, Rosemary Vojnik, Jonasel Roque, Cynthia Perez, George W. Lim, Steven Y. Chang, Rebecca Beutler, Trisha Agarwal, Julia Vargas, Marc Moss, Amiran Baduashvili, Lakshmi Chauhan, Lani L. Finck, Michelle Howell, Robert C. Hyzy, Pauline K. Park, Kristine Nelson, Jake I. McSparron, Ivan N. Co, Bonnie R. Wang, Shijing Jia, Barbara Sullins, Sinan Hanna, Norman Olbrich, Lynne D. Richardson, Rahul Nair, Obiageli Offor, Brenda Lopez, Omowunmi Amosu, Hiwet Tzehaie, Thomas E. Terndrup, Herbert P. Wiedemann, Abhijit Duggal, Nirosshan Thiruchelvam, Kiran Ashok, Alexander H. King, Omar Mehkri, Kristin Hudock, Simra Kiran, Harshada More, Tammy Roads, Jamie Martinkovic, Sarah Kennedy, Bryce H. Robinson, Catherine L. Hough, Olivia F. Krol, Mistry Kinjal, Emmanuel Mills, Madeline McDougal, Rupali Deshmukh, Peter Chen, Sam S. Torbati, Yuri Matusov, June Choe, Niree A. Hindoyan, Susan E. Jackman, Emad Bayoumi, Timothy Wynter, Antonina Caudill, Ethan Pascual, Gregg J. Clapham, Lisa Herrera, Cristabelle Ojukwu, Shaunt Mehdikhani, D. Shane O'Mahony, Sonam T. Nyatsatsang, David M. Wilson, Julie A. Wallick, Chadwick Miller, Keven W. Gibbs, Lori S. Flores, Mary E. LaRose, Leigha D. Landreth, Peter E. Morris, Jamie L. Sturgill, Evan P. Cassity, Sanjay Dhar, Ashley A. Montgomery-Yates, Sara N. Pasha, Kirby P. Mayer, Brittany Bissel, Joseph Bledsoe, Samuel Brown, Michael Lanspa, Lindsey Leither, Brent P. Armbruster, Quinn Montgomery, Darrin Applegate, Naresh Kumar, Melissa Fergus, Erna Serezlic, Karah Imel, Ghazal Palmer, Brandon Webb, Valerie T. Aston, Jakea Johnson, Christopher Gray, Margaret Hays, Megan Roth, Adriana Sánchez, Laura Popielski, Heather Rivasplata, Melissa Turner, Michael Vjecha, Tianna Petersen, Dena Kamel, Laura Hansen, Claudia Sanchez Lucas, Natalie DellaValle, Sonia Gonzales, James Scott, David Wyles, Ivor Douglas, Jason Haukoos, Kevin Kamis, Caitlin Robinson, Jason V. Baker, Anne Frosch, Rachael Goldsmith, Hodan Jibrell, Melanie Lo, Jonathan Klaphake, Shari Mackedanz, Linh Ngo, Kelly Garcia-Myers, Norman Markowitz, Erika Pastor, Mayur Ramesh, Indira Brar, Emanuel Rivers, Princy Kumar, Maximiliano Menna, Kousick Biswas, Cristin Harrington, Alex Delp, Lavannya Pandit, Casey Hines-Munson, John Van, Laura Dillon, Yiqun Want, Paola Lichtenberger, Gio Baracco, Carol Ramos, Lauren Bjork, Melyssa Sueiro, Phyllis Tien, Heather Freasier, Theresa Buck, Hafida Nekach, Stephanie Nagy-Agren, Shikha Vasudeva, Tracy Ochalek, Brentin Roller, Chinh Nguyen, Amani Mikail, Dorthe Raben, Tomas O. Jensen, Bitten Aagaard, Charlotte B. Nielsen, Katharina Krapp, Bente Rosdahl Nykjær, Katja Lisa Kanne, Anne Louise Grevsen, Zillah Maria Joensen, Tina Bruun, Ane Bojesen, Frederik Woldbye, Nick E. Normand, Frederik V.L. Esmann, Clara Lundetoft Clausen, Nichlas Hovmand, Karen Brorup Pedersen, Louise Thorlacius-Ussing, Michaela Tinggaard, Dorthe S. Høgsberg, Ema Rastoder, Thobias Kamstrup, Christina Marisa Bergsøe, Lars Østergaard, Nina Breinholt Stærke, Isik S. Johansen, Fredrikke C. Knudtzen, Lykke Larsen, Mathias A. Hertz, Thilde Fabricius, Marie Helleberg, Jan Gerstoft, Tomas Østergaard Jensen, Birgitte Lindegaard, Thomas Ingemann Pedersen, Birgit Thorup Røge, Sandra Valborg Løfberg, Thomas Michael Hansen, Ariella Denize Nielsen, Sebastian Leicht von Huth, Henrik Nielsen, Rikke Krog Thisted, Daria Podlekareva, Stine Johnsen, Helle Frost Andreassen, Lars Pedersen, Cecilia Ebba Clara Ellinor Lindnér, Lothar Wiese, Lene Surland Knudsen, Nikolaj Julian Skrøder Nytofte, Signe Ravn Havmøller, Roger Paredes, Maria Exposito, Eduardo Fernández-Cruz, José Muñoz, Jose R. Arribas, Vicente Estrada, Juan P. Horcajada, Joaquin Burgos, Jose Luis Morales-Rull, Dominique L. Braun, Emily West, Khadija M'Rabeth-Bensalah, Mareile L. Eichinger, Manuela Grüttner-Durmaz, Christina Grube, Veronika Zink, Andrzej Horban, Agnieszka Bednarska, Natalia Jurek, Gerd Fätkenheuer, Jakob J. Malinm, Gail Matthews, Anthony Kelleher, Gesalit Cabrera, Catherine Carey, Sally Hough, Sophie Virachit, Amy Zhong, Barnaby E. Young, Po Ying Chia, Tau Hong Lee, Ray J. Lin, David Lye, Sean Ong, Ser Hon Puah, Tsin Wen Yeo, Shiau Hui Diong, Juwinda Ongko, Fleur Hudson, Mahesh KB Parmar, Anna Goodman, Jonathan Badrock, Adam Gregory, Nicola Harris, Giota Touloumi, Nikos Pantaz, Vicky Gioukari, Joseph Lutaakome, Cissy M. Kityo, Henry Mugerwa, Francis Kiweewa, Anu Osinusi, Craig Tipple, Angela Willis, Amanda Peppercorn, Helen Watson, Elizabeth Alexander, Erik Mogalian, Leo Lin, Xiao Ding, Li Yan, Jean-Luc Girardet, Ji Ma, Zhi Hong, Amy Adams, Sara Albert, Abby Balde, Michelle Baracz, Beth Baseler, Nancy Becker, Mona Bielica, Shere Billouin-Frazier, Jennifer Cash, Jay Choudhary, Suzanne Dolney, Mary Dixon, Carolyn Eyler, Leanna Frye, Michael Galcik, Jensen Gertz, Lisa Giebeig, Neelam Gulati, Liz Hankinson, Debbie Hissey, Debi Hogarty, Matt Hohn, H Preston Holley, Lisa Hoopengardner, Lynda Huber, Shirley Jankelevich, Gary Krauss, Eileen Lake, Jessica Linton, Leah MacDonald, Meryan Manandhar, Mary Spinelli-Nadzam, Charles Oluremi, Calvin Proffitt, Erin Rudzinski, Jen Sandrus, Marylu Schaffhauser, Adam Schechner, Connie Suders, Norman P. Gerry, Kenneth Smith, Courtney Solomon, Amanda Kubernac, Marium Rashid, Bhakti Patel, Robert Kubernac, Joseph Murphy, Marie L. Hoover, Craig Brown, Nadine DuChateau, Adam Flosi, Les Johnson, Amy Treagus, and Christine Wenner

Subjects
Adult, Male, Adolescent, SARS-CoV-2, Comment, COVID-19, Antibodies, Monoclonal, Articles, Middle Aged, Antibodies, Monoclonal, Humanized, Antibodies, Neutralizing, COVID-19/drug therapy, COVID-19 Drug Treatment, Hospitalization, Infectious Diseases, Antineoplastic Agents, Immunological, Treatment Outcome, Antibodies, Monoclonal, Humanized/therapeutic use, Double-Blind Method, Humans, Female, Aged
Abstract

BACKGROUND: We aimed to assess the efficacy and safety of two neutralising monoclonal antibody therapies (sotrovimab [Vir Biotechnology and GlaxoSmithKline] and BRII-196 plus BRII-198 [Brii Biosciences]) for adults admitted to hospital for COVID-19 (hereafter referred to as hospitalised) with COVID-19.METHODS: In this multinational, double-blind, randomised, placebo-controlled, clinical trial (Therapeutics for Inpatients with COVID-19 [TICO]), adults (aged ≥18 years) hospitalised with COVID-19 at 43 hospitals in the USA, Denmark, Switzerland, and Poland were recruited. Patients were eligible if they had laboratory-confirmed SARS-CoV-2 infection and COVID-19 symptoms for up to 12 days. Using a web-based application, participants were randomly assigned (2:1:2:1), stratified by trial site pharmacy, to sotrovimab 500 mg, matching placebo for sotrovimab, BRII-196 1000 mg plus BRII-198 1000 mg, or matching placebo for BRII-196 plus BRII-198, in addition to standard of care. Each study product was administered as a single dose given intravenously over 60 min. The concurrent placebo groups were pooled for analyses. The primary outcome was time to sustained clinical recovery, defined as discharge from the hospital to home and remaining at home for 14 consecutive days, up to day 90 after randomisation. Interim futility analyses were based on two seven-category ordinal outcome scales on day 5 that measured pulmonary status and extrapulmonary complications of COVID-19. The safety outcome was a composite of death, serious adverse events, incident organ failure, and serious coinfection up to day 90 after randomisation. Efficacy and safety outcomes were assessed in the modified intention-to-treat population, defined as all patients randomly assigned to treatment who started the study infusion. This study is registered with ClinicalTrials.gov, NCT04501978.FINDINGS: Between Dec 16, 2020, and March 1, 2021, 546 patients were enrolled and randomly assigned to sotrovimab (n=184), BRII-196 plus BRII-198 (n=183), or placebo (n=179), of whom 536 received part or all of their assigned study drug (sotrovimab n=182, BRII-196 plus BRII-198 n=176, or placebo n=178; median age of 60 years [IQR 50-72], 228 [43%] patients were female and 308 [57%] were male). At this point, enrolment was halted on the basis of the interim futility analysis. At day 5, neither the sotrovimab group nor the BRII-196 plus BRII-198 group had significantly higher odds of more favourable outcomes than the placebo group on either the pulmonary scale (adjusted odds ratio sotrovimab 1·07 [95% CI 0·74-1·56]; BRII-196 plus BRII-198 0·98 [95% CI 0·67-1·43]) or the pulmonary-plus complications scale (sotrovimab 1·08 [0·74-1·58]; BRII-196 plus BRII-198 1·00 [0·68-1·46]). By day 90, sustained clinical recovery was seen in 151 (85%) patients in the placebo group compared with 160 (88%) in the sotrovimab group (adjusted rate ratio 1·12 [95% CI 0·91-1·37]) and 155 (88%) in the BRII-196 plus BRII-198 group (1·08 [0·88-1·32]). The composite safety outcome up to day 90 was met by 48 (27%) patients in the placebo group, 42 (23%) in the sotrovimab group, and 45 (26%) in the BRII-196 plus BRII-198 group. 13 (7%) patients in the placebo group, 14 (8%) in the sotrovimab group, and 15 (9%) in the BRII-196 plus BRII-198 group died up to day 90.INTERPRETATION: Neither sotrovimab nor BRII-196 plus BRII-198 showed efficacy for improving clinical outcomes among adults hospitalised with COVID-19.FUNDING: US National Institutes of Health and Operation Warp Speed.

Published
2022
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9. Genetics of Idiopathic Pulmonary Fibrosis

Author

Justin M. Oldham, Imre Noth, and Andrew Barros

Subjects
business.industry, Large effect size, Common gene, Complex disease, Interstitial lung disease, General Medicine, respiratory system, 030204 cardiovascular system & hematology, medicine.disease, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, 03 medical and health sciences, Disease susceptibility, Idiopathic pulmonary fibrosis, 0302 clinical medicine, Immunology, Disease risk, medicine, Humans, In patient, 030212 general & internal medicine, Lung Diseases, Interstitial, business
Abstract

Idiopathic pulmonary fibrosis (IPF) is the most common form of interstitial lung disease. IPF is a complex disease, with environmental and genetic factors variably contributing to disease susceptibility and outcomes. A host of common gene variants with modest effect size impart disease risk in patients with sporadic IPF, while rare variants with large effect size influence disease risk in those with familial interstitial pneumonia. In this review, we highlight several common and rare variants underpinning IPF risk and call attention to recently published studies informing our understanding of this risk.

Published
2019
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10. Female Hormonal Regulation of pSTAT3 Results in Reduced Mortality Due to Enhanced TGF-β1-Mediated Pulmonary Fibrosis and Less IL-17A

Author

Imre Noth, Dawn C. Newcomb, Lindsay J. Celada, Wonder P. Drake, B. Shah-Gandhi, K. Abel, O.S. Chioma, H. Wei, and Andrew Barros

Subjects
medicine.medical_specialty, Endocrinology, business.industry, Internal medicine, Pulmonary fibrosis, medicine, medicine.disease, business, Hormone, Transforming growth factor
Published
2020
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12. EFFECT OF ARTERIAL CATHETER ON VASOPRESSOR USE IN PATIENTS WITH SHOCK: A PROPENSITY SCORE MATCHING ANALYSIS ON A MULTI-CENTER RETROSPECTIVE COHORT

Author

Susana Margare, Susan McLean, Andrew Barros, Hyunjoon Lee, Sura Alqaisi, Hieu Nguyen, Saira Samani, and Priscilla Rivera

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Retrospective cohort study, Arterial catheter, Critical Care and Intensive Care Medicine, Shock (circulatory), Internal medicine, Propensity score matching, medicine, Cardiology, Center (algebra and category theory), In patient, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Published
2020
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17. The Civilianization of War : The Changing Civil–Military Divide, 1914–2014

Author

Andrew Barros, Martin Thomas, Andrew Barros, and Martin Thomas

Subjects
Civilians in war--History--20th century, Civilians in war--History--21st century
Abstract

Distinguishing between civilians and combatants is a central aspect of modern conflicts. Yet such distinctions are rarely upheld in practice. The Civilianization of War offers new ways of understanding civilians'exposure to violence in war. Each chapter explores a particular approach to the political, legal, or cultural distinctions between civilians and combatants during twentieth-century and contemporary conflicts. The volume as a whole suggests that the distinction between combatants and non-combatants is dynamic and oft-times unpredictable, rather than fixed and reciprocally understood. Contributors offer new insights into why civilian targeting has become a strategy for some, and how in practice its avoidance can be so difficult to achieve. Several discuss distinct population groups that have been particularly exposed to wartime violence, including urban populations facing aerial bombing, child soldiers, captives, and victims of sexual violence. The book thus offers multiple perspectives on the civil–military divide within modern conflicts, an issue whose powerful contemporary resonance is all too apparent.

Published
2018

19. [Untitled]

Author

Alexandra Kadl and Andrew Barros

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Hemorrhagic shock, Cardiology, Medicine, Critical Care and Intensive Care Medicine, business
Published
2019
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24. Debating British Decisionmaking toward Nazi Germany in the 1930s

Author

Norrin M. Ripsman, Talbot Imlay, Andrew Barros, Evan N. Resnick, and Jack S. Levy

Subjects
International relations, Sociology and Political Science, Argument, Law, Political science, Political Science and International Relations, Analogy, Nazi Germany, Security studies, Administration (government), Period (music), Appeasement
Abstract

Ripsman and Levy’s argument merits attention for at least two related reasons. The arst is the renewal of interest in appeasement within the international relations and security studies aelds. Piqued by the repeated use (or misuse) of the appeasement analogy by the administration of George W. Bush, several scholars have recently turned their attention to the international politics of the 1930s to assess what lessons should be drawn from the events of the period for today’s decisionmakers. 2 More speciacally, they question whether appeasement is sometimes justiaed or is always misguided. The second reason is that many of these scholars embrace what might be called a “rational

Published
2009
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25. STRATEGIC BOMBING AND RESTRAINT IN ‘TOTAL WAR’, 1915–1918

Author

Andrew Barros

Subjects
History, Politics, Government, Mobilization, Home front, Political science, Political economy, Total war, Strategic bombing, First world war
Abstract

Recent studies of ‘total war’ depict a process of inexorable expansion leading to an often nebulous linkage of everything to war. This article takes the study of ‘total war’ in the opposite direction by studying a specific example of strategic restraint. It examines how the French bombing strategy that was developed over the course of the First World War went to considerable lengths to maintain a distinction between the civilian and the military. The article studies France's restraint by highlighting the strategic, geographical, institutional, and economic factors upon which it was built. It then goes on to examine the political pressures for an expansion of bombing which proved incapable of overturning this policy. Finally, it contrasts French restraint with that of its key ally, Great Britain. There, bombing developed into a strategic weapon designed to destroy the ‘home front’. This study of restraint underscores the importance of limits, and the attendant choices government has to make, in understanding the course and intensity of a country's mobilization for modern war.

Published
2009
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26. Disarmament as a weapon: Anglo-French relations and the problems of enforcing German disarmament, 1919–28

Author

Andrew Barros

Subjects
German, Power (social and political), Disarmament, Sociology and Political Science, Political science, Law, Political Science and International Relations, language, League, Treaty, language.human_language
Abstract

This article examines the conflicting French and British definitions and policies towards the enforced disarmament of Germany that was agreed upon by the Allies at Versailles. It contrasts the French definition of disarmament, ‘moral disarmament’, which required convincing controls over Germany's material capability for war and the country's desire to use force, with the much narrower British view, which sought the rapid dismantling of Berlin's physical armaments. These irreconcilable views further divided the two countries and fostered differences over intelligence estimates of German power and the role of the League of Nations in German disarmament.

Published
2006
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27. Reviews of Books

Author

Arthur M. Eckstein, Julia Kindt, Paul J. Bolt, James A. Brundage, Charles C. Stewart, Jan Luiten van Zanden, Daniel Moran, Thomas E. Burman, Julius Kirshner, Nigel D. White, Clifford J. Rogers, Donald Weinstein, John E. Wills, Ronald G. Asch, Kenneth Morgan, Paul Douglas Lockhart, John C. Rule, Robert Travers, Donald Denoon, Julian Wright, Barry Gough, Norman Hampson, William Philpott, Neville Thompson, Anthony Rhinelander, Gutty Nashat, Trevor Burnard, Dane Kennedy, John M. MacKenzie, Patricia Grimshaw, Ilaria Favretto, Sigurd Hess, Niel Gunson, Diana Lary, Tim Travers, John Gooch, Andrew Barros, A. S. Kanya-Forstner, Stig Thøgersen, Roger Beaumont, Leonard V. Smith, Christian Leitz, Stephen G. Craft, Samir Saul, David Harkness, Anthony Best, Alan Cassels, Alexander De Grand, Suzanne Brown-Fleming, Lawrence D. Stokes, Lynne Taylor, Ingmar Oldberg, Craig M. Cameron, Christopher Waters, Anthony Adamthwaite, Arnold Krammer, A. Hamish Ion, James Jupp, Robert G. Moeller, Anthony J. Steinhoff, Alessandro Brogi, Thomas Borstelmann, J. L. Granatstein, Richard C. Thornton, David Lowe, Keith Robbins, Alan Sharp, Antonio Cassese, Heikki Mikkeli, and Andrew J. Bacevich

Subjects
Cultural Studies, History, Sociology and Political Science
Published
2003
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29. A window on the ‘trust’: The case of Ado Birk

Author

Andrew Barros

Subjects
History, National security, Computer science, business.industry, Political Science and International Relations, Window (computing), business, Computer security, computer.software_genre, computer
Abstract

(1995). A window on the ‘trust’: The case of Ado Birk. Intelligence and National Security: Vol. 10, No. 2, pp. 273-293.

Published
1995
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32. Book reviews

Author

Keith Jeffery, Donald Avery, Sharam M. Taromsari, Andrew Barros, Ralph Bennett, Rhodri Jeffreys‐Jones, Anthony Short, Christopher Simpson, Alan R. Booth, James J. Wirtz, Brian Holden Reid, Tim Travers, Peter G. Boyle, B. Nelson Macpherson, Michael A. Barnhart, and Christopher Wyatt

Subjects
History, Political Science and International Relations
Published
1993
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33. Book reviews

Author

John Starnes, Myles Robertson, Christon I. Archer, Eliezer Tauber, Andrew Barros, Davina Miller, Keith Jeffery, Barry Baldwin, J.F.V. Keiger, James J. Wirtz, Richard Thurlow, B. Nelson MacPherson, Ronald Haycock, Joseph F. Ryan, Nils Petter Gleditsch, John Gimbel, and Alan R. Booth

Subjects
History, Political Science and International Relations
Published
1992
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35. Les dangers du sport et de l'éducation physique

Author

Andrew Barros

Subjects
History
Abstract

L’experience de la Premiere Guerre mondiale se traduisit chez les Francais notamment par leur souci d’etudier la puissance militaire allemande durant les annees 1920. Apres la guerre, le « potentiel de guerre » d’un pays incluait des facteurs aussi importants mais difficiles a evaluer que l’unite et la cohesion nationales. Dans ce nouveau contexte, les sports organises furent consideres comme un indicateur supplementaire des intentions militaires et du potentiel de guerre d’un pays. Le Deuxieme Bureau francais a commence a prendre en compte les efforts de l’Allemagne visant a promouvoir les sports et l’education physique dans son analyse du revanchisme allemand et de son potentiel militaire. Les resultats de leur investigation s’avererent d’autant plus inquietants que la comparaison avec la situation en France leur etait defavorable.

Published
2003
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