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1. Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa

Author

Janivara, Rohini, Chen, Wenlong C., Hazra, Ujani, Baichoo, Shakuntala, Agalliu, Ilir, Kachambwa, Paidamoyo, Simonti, Corrine N., Brown, Lyda M., Tambe, Saanika P., Kim, Michelle S., Harlemon, Maxine, Jalloh, Mohamed, Muzondiwa, Dillon, Naidoo, Daphne, Ajayi, Olabode O., Snyper, Nana Yaa, Niang, Lamine, Diop, Halimatou, Ndoye, Medina, Mensah, James E., Abrahams, Afua O. D., Biritwum, Richard, Adjei, Andrew A., Adebiyi, Akindele O., Shittu, Olayiwola, Ogunbiyi, Olufemi, Adebayo, Sikiru, Nwegbu, Maxwell M., Ajibola, Hafees O., Oluwole, Olabode P., Jamda, Mustapha A., Pentz, Audrey, Haiman, Christopher A., Spies, Petrus V., van der Merwe, André, Cook, Michael B., Chanock, Stephen J., Berndt, Sonja I., Watya, Stephen, Lubwama, Alexander, Muchengeti, Mazvita, Doherty, Sean, Smyth, Natalie, Lounsbury, David, Fortier, Brian, Rohan, Thomas E., Jacobson, Judith S., Neugut, Alfred I., Hsing, Ann W., Gusev, Alexander, Aisuodionoe-Shadrach, Oseremen I., Joffe, Maureen, Adusei, Ben, Gueye, Serigne M., Fernandez, Pedro W., McBride, Jo, Andrews, Caroline, Petersen, Lindsay N., Lachance, Joseph, and Rebbeck, Timothy R.

Published
2024
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2. Germline sequence variation in cancer genes in Rwandan breast and prostate cancer cases

Author

Manirakiza, Achille VC., Baichoo, Shakuntala, Uwineza, Annette, Dukundane, Damas, Uwinkindi, Francois, Ngendahayo, Edouard, Rubagumya, Fidel, Muhawenimana, Emmanuel, Nsabimana, Nicaise, Nzeyimana, Innocent, Maniragaba, Theoneste, Ntirenganya, Faustin, Rurangwa, Ephrem, Mugenzi, Pacifique, Mutamuliza, Janviere, Runanira, Daniel, Niyibizi, Brandon A., Rugengamanzi, Eulade, Besada, Jeffrey, Nielsen, Sarah M., Bucknor, Brianna, Nussbaum, Robert L., Koeller, Diane, Andrews, Caroline, Mutesa, Leon, Fadelu, Temidayo, and Rebbeck, Timothy R.

Published
2024
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3. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.

Author

Wang, Anqi, Shen, Jiayi, Rodriguez, Alex, Saunders, Edward, Chen, Fei, Janivara, Rohini, Darst, Burcu, Sheng, Xin, Xu, Yili, Chou, Alisha, Benlloch, Sara, Dadaev, Tokhir, Brook, Mark, Plym, Anna, Sahimi, Ali, Hoffman, Thomas, Takahashi, Atushi, Matsuda, Koichi, Momozawa, Yukihide, Fujita, Masashi, Laisk, Triin, Figuerêdo, Jéssica, Muir, Kenneth, Ito, Shuji, Liu, Xiaoxi, Uchio, Yuji, Kubo, Michiaki, Kamatani, Yoichiro, Lophatananon, Artitaya, Wan, Peggy, Andrews, Caroline, Lori, Adriana, Choudhury, Parichoy, Schleutker, Johanna, Tammela, Teuvo, Sipeky, Csilla, Auvinen, Anssi, Giles, Graham, Southey, Melissa, MacInnis, Robert, Cybulski, Cezary, Wokolorczyk, Dominika, Lubinski, Jan, Rentsch, Christopher, Cho, Kelly, Mcmahon, Benjamin, Neal, David, Donovan, Jenny, Hamdy, Freddie, Martin, Richard, Nordestgaard, Borge, Nielsen, Sune, Weischer, Maren, Bojesen, Stig, Røder, Andreas, Stroomberg, Hein, Batra, Jyotsna, Chambers, Suzanne, Horvath, Lisa, Clements, Judith, Tilly, Wayne, Risbridger, Gail, Gronberg, Henrik, Aly, Markus, Szulkin, Robert, Eklund, Martin, Nordstrom, Tobias, Pashayan, Nora, Dunning, Alison, Ghoussaini, Maya, Travis, Ruth, Key, Tim, Riboli, Elio, Park, Jong, Sellers, Thomas, Lin, Hui-Yi, Albanes, Demetrius, Weinstein, Stephanie, Cook, Michael, Mucci, Lorelei, Giovannucci, Edward, Lindstrom, Sara, Kraft, Peter, Hunter, David, Penney, Kathryn, Turman, Constance, Tangen, Catherine, Goodman, Phyllis, Thompson, Ian, Hamilton, Robert, Fleshner, Neil, Finelli, Antonio, Parent, Marie-Élise, Stanford, Janet, Ostrander, Elaine, Koutros, Stella, Beane Freeman, Laura, Stampfer, Meir, Wolk, Alicja, and Håkansson, Niclas

Subjects
Humans, Male, Black People, Genetic Predisposition to Disease, Genome-Wide Association Study, Hispanic or Latino, Polymorphism, Single Nucleotide, Prostatic Neoplasms, Risk Factors, White People, Asian People
Abstract

The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk variants for prostate cancer, increasing the total number of risk variants to 451. An externally replicated multi-ancestry GRS was associated with risk that ranged from 1.8 (per standard deviation) in African ancestry men to 2.2 in European ancestry men. The GRS was associated with a greater risk of aggressive versus non-aggressive disease in men of African ancestry (P = 0.03). Our study presents novel prostate cancer susceptibility loci and a GRS with effective risk stratification across ancestry groups.

Published
2023

5. Multinational, Multicenter Evaluation of Prostate Cancer Tissue in Sub-Saharan Africa: Challenges and Opportunities

Author

van Wyk, Abraham C., Lal, Priti, Ogunbiyi, J. Olufemi, Kyokunda, Lynnette, Hobenu, Fred, Dial, Cherif, Jalloh, Mohamed, Gyasi, Richard, Oluwole, Olabode P., Abrahams, Afua D., Botha, Adam R., Mtshali, Nompumelelo Zamokuhle, Andrews, Caroline, Mante, Sunny, Adusei, Ben, Gueye, Serigne M., Mensah, James E., Adjei, Andrew Anthony, Tettey, Yao, Adebiyi, Akin, Aisuodionoe-Shadrach, Oseremen, Eniola, Sefiu Bolarinwa, Serna, Amparo, Yamoah, Kosj, Chen, Wenlong Carl, Fernandez, Pedro, Robinson, Brian D., Mosquera, Juan Miguel, Hsing, Ann W., Agalliu, Ilir, and Rebbeck, Timothy R.

Published
2024
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6. Universality and Diversity in Event Cognition and Language

Author

Ji, Yue, Andrews, Caroline, Sauppe, Sebastian, Flecken, Monique, Zariquiey, Roberto, laka, itziar, Daum, Moritz M., Ünal, Ercenur, Papafragou, Anna, Rissman, Lilia, van Putten, Saskia, Majid, Asifa, Manhardt, Francie, Özyürek, Asli, Isasi-Isasmendi, Arrate, Meyer, Martin, and Bickel, Balthasar

Subjects
Linguistics, Psychology, Concepts and categories, Event cognition, Language and thought, Perception, Representation, Eye tracking, Quantitative Behavior
Abstract

Humans are surprisingly adept at interpreting what is happening around them – they spontaneously and rapidly segment and organize their dynamic experience into coherent event construals. Such event construals may offer a starting point for assembling a linguistic description of the event during speaking (Levelt, 1989). However, the precise format of event representations and their mapping to language have remained elusive, partly because research on how people mentally segment and perceive events (see Radvansky & Zacks, 2014 for a review) has largely proceeded separately from analyses of how events are encoded in language (see Truswell, 2019 for a review).

Published
2022

7. Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders

Author

Abarca-Barriga, Hugo, Al-Haddad, Christiane, Berman, Jeffrey L., Bothun, Erick D., Capasso, Jenina, Chacon-Camacho, Oscar Francisco, Chang, Lan, Christiansen, Stephen P., Ciccarelli, Maria Laura, Cordonnier, Monique, Cox, Gerald F., Curry, Cynthia J., Dagi, Linda R., Lee Dahm, Thomas, David, Karen L., Davitt, Bradley V., De Berardinis, Teresa, Demer, Joseph L., Désir, Julie, D’Esposito, Fabiana, Drack, Arlene V., Eggenberger, Eric, Elder, James E., Elliott, Alexandra T., Epley, K. David, Feldman, Hagit Baris, Ferreira, Carlos R., Flaherty, Maree P., Fulton, Anne B., Gerth-Kahlert, Christina, Gottlob, Irene, Grill, Stephen, Halliday, Dorothy J., Hanisch, Frank, Hay, Eleanor, Heidary, Gena, Holder, Christopher, Horton, Jonathan C., Iannaccone, Alessandro, Isenberg, Sherwin J., Johnston, Suzanne C., Kahana, Alon, Katowitz, James A., Kazlas, Melanie, Kerr, Natalie C., Kimonis, Virginia, Ko, Melissa W., Koc, Feray, Larsen, Dorte Ancher, Lay-Son, Guillermo, Ledoux, Danielle M., Levin, Alex V., Levy, Richard L., Lyons, Christopher J., Mackey, David A., Magli, Adriano, Mantagos, Iason S., Marti, Candice, Maystadt, Isabelle, McKenzie, Fiona, Menezes, Manoj P., Mikail, Claudia N., Miller, David T., Miller, Kathryn Bisceglia, Mills, Monte D., Miyana, Kaori, Moller, H.U., Mullineaux, Lisa, Nishimura, Julie K., Noble, A. Gwendolyn, Pandey, Pramod Kumar, Pavone, Piero, Penzien, Johann, Petersen, Robert, Phalen, James A., Poduri, Annapurna, Polo, Claudia R., Prasov, Lev, Ramos, Feliciano J., Ramos-Caceres, Maria, Robb, Richard M., Rossillion, Béatrice, Sahin, Mustafa, Singer, Harvey S., Smith, Lois E.H., Sorkin, Jeffrey A., Soul, Janet S., Staffieri, Sandra E., Stalker, Heather J., Stasheff, Steven F., Strassberg, Sonya, Strominger, Mitchell B., Taranath, Deepa Ajay, Thomas, Ioan Talfryn, Traboulsi, Elias I., Ugrin, Maria Cristina, VanderVeen, Deborah K., Vincent, Andrea L., Vogel G, Marlene C., Wabbels, Bettina, Wong, Agnes M.F., Woods, C. Geoffrey, Wu, Carolyn, Yang, Edward, Yeung, Alison, Young, Terri L., Zenteno, Juan C., Zubcov-Iwantscheff, Alexandra A., Zwaan, Johan, Jurgens, Julie A., Barry, Brenda J., Chan, Wai-Man, MacKinnon, Sarah, Whitman, Mary C., Matos Ruiz, Paola M., Pratt, Brandon M., England, Eleina M., Pais, Lynn, Lemire, Gabrielle, Groopman, Emily, Glaze, Carmen, Russell, Kathryn A., Singer-Berk, Moriel, Di Gioia, Silvio Alessandro, Lee, Arthur S., Andrews, Caroline, Shaaban, Sherin, Wirth, Megan M., Bekele, Sarah, Toffoloni, Melissa, Bradford, Victoria R., Foster, Emma E., Berube, Lindsay, Rivera-Quiles, Cristina, Mensching, Fiona M., Sanchis-Juan, Alba, Fu, Jack M., Wong, Isaac, Zhao, Xuefang, Wilson, Michael W., Weisburd, Ben, Lek, Monkol, Brand, Harrison, Talkowski, Michael E., MacArthur, Daniel G., O’Donnell-Luria, Anne, Robson, Caroline D., Hunter, David G., and Engle, Elizabeth C.

Published
2024
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8. Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry

Author

Chen, Fei, Madduri, Ravi K., Rodriguez, Alex A., Darst, Burcu F., Chou, Alisha, Sheng, Xin, Wang, Anqi, Shen, Jiayi, Saunders, Edward J., Rhie, Suhn K., Bensen, Jeannette T., Ingles, Sue A., Kittles, Rick A., Strom, Sara S., Rybicki, Benjamin A., Nemesure, Barbara, Isaacs, William B., Stanford, Janet L., Zheng, Wei, Sanderson, Maureen, John, Esther M., Park, Jong Y., Xu, Jianfeng, Wang, Ying, Berndt, Sonja I., Huff, Chad D., Yeboah, Edward D., Tettey, Yao, Lachance, Joseph, Tang, Wei, Rentsch, Christopher T., Cho, Kelly, Mcmahon, Benjamin H., Biritwum, Richard B., Adjei, Andrew A., Tay, Evelyn, Truelove, Ann, Niwa, Shelley, Sellers, Thomas A., Yamoah, Kosj, Murphy, Adam B., Crawford, Dana C., Patel, Alpa V., Bush, William S., Aldrich, Melinda C., Cussenot, Olivier, Petrovics, Gyorgy, Cullen, Jennifer, Neslund-Dudas, Christine M., Stern, Mariana C., Kote-Jarai, Zsofia, Govindasami, Koveela, Cook, Michael B., Chokkalingam, Anand P., Hsing, Ann W., Goodman, Phyllis J., Hoffmann, Thomas J., Drake, Bettina F., Hu, Jennifer J., Keaton, Jacob M., Hellwege, Jacklyn N., Clark, Peter E., Jalloh, Mohamed, Gueye, Serigne M., Niang, Lamine, Ogunbiyi, Olufemi, Idowu, Michael O., Popoola, Olufemi, Adebiyi, Akindele O., Aisuodionoe-Shadrach, Oseremen I., Ajibola, Hafees O., Jamda, Mustapha A., Oluwole, Olabode P., Nwegbu, Maxwell, Adusei, Ben, Mante, Sunny, Darkwa-Abrahams, Afua, Mensah, James E., Diop, Halimatou, Van Den Eeden, Stephen K., Blanchet, Pascal, Fowke, Jay H., Casey, Graham, Hennis, Anselm J., Lubwama, Alexander, Thompson, Ian M., Jr., Leach, Robin, Easton, Douglas F., Preuss, Michael H., Loos, Ruth J., Gundell, Susan M., Wan, Peggy, Mohler, James L., Fontham, Elizabeth T., Smith, Gary J., Taylor, Jack A., Srivastava, Shiv, Eeles, Rosaline A., Carpten, John D., Kibel, Adam S., Multigner, Luc, Parent, Marie-Élise, Menegaux, Florence, Cancel-Tassin, Geraldine, Klein, Eric A., Andrews, Caroline, Rebbeck, Timothy R., Brureau, Laurent, Ambs, Stefan, Edwards, Todd L., Watya, Stephen, Chanock, Stephen J., Witte, John S., Blot, William J., Michael Gaziano, J., Justice, Amy C., Conti, David V., and Haiman, Christopher A.

Published
2023
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9. A New Argument for Co-Active Parses During Language Comprehension

Author

Dillon, Brian, Andrews, Caroline, Rotello, Caren M, and Wagers, Matthew

Subjects
Biological Psychology, Cognitive and Computational Psychology, Psychology, Clinical Research, Adult, Comprehension, Humans, Models, Psychological, Psycholinguistics, ROC Curve, Reading, Signal Detection, Psychological, Young Adult, sentence processing, signal detection theory, ROCs, syntactic ambiguity, computational modeling, Cognitive Sciences, Experimental Psychology, Cognitive and computational psychology
Abstract

One perennially important question for theories of sentence comprehension is whether the human sentence processing mechanism is parallel (i.e., it simultaneously represents multiple syntactic analyses of linguistic input) or serial (i.e., it constructs only a single analysis at a time). Despite its centrality, this question has proven difficult to address for both theoretical and methodological reasons (Gibson & Pearlmutter, 2000; Lewis, 2000). In the present study, we reassess this question from a novel perspective. We investigated the well-known ambiguity advantage effect (Traxler, Pickering, & Clifton, 1998) in a speeded acceptability judgment task. We adopted a signal detection theoretic approach to these data, with the goal of determining whether speeded judgment responses were conditioned on one or multiple syntactic analyses. To link these results to incremental parsing models, we developed formal models to quantitatively evaluate how serial and parallel parsing models should impact perceived sentence acceptability in our task. Our results suggest that speeded acceptability judgments are jointly conditioned on multiple parses of the input, a finding that is overall more consistent with parallel parsing models than serial models. Our study thus provides a new, psychophysical argument for coactive parses during language comprehension. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Published
2019

10. Humans and great apes visually track event roles in similar ways.

Author

Wilson, Vanessa A. D., Sauppe, Sebastian, Brocard, Sarah, Ringen, Erik, Daum, Moritz M., Wermelinger, Stephanie, Gu, Nianlong, Andrews, Caroline, Isasi-Isasmendi, Arrate, Bickel, Balthasar, and Zuberbühler, Klaus

Subjects
HOMINIDS, INFANTS, COGNITION, SYNTAX (Grammar), GAZE, ADULTS
Abstract

Human language relies on a rich cognitive machinery, partially shared with other animals. One key mechanism, however, decomposing events into causally linked agent–patient roles, has remained elusive with no known animal equivalent. In humans, agent–patient relations in event cognition drive how languages are processed neurally and expressions structured syntactically. We compared visual event tracking between humans and great apes, using stimuli that would elicit causal processing in humans. After accounting for attention to background information, we found similar gaze patterns to agent–patient relations in all species, mostly alternating attention to agents and patients, presumably in order to learn the nature of the event, and occasionally privileging agents under specific conditions. Six-month-old infants, in contrast, did not follow agent–patient relations and attended mostly to background information. These findings raise the possibility that event role tracking, a cognitive foundation of syntax, has evolved long before language but requires time and experience to become ontogenetically available. Are only humans capable of tracking agent/patient roles during events, a cognitive foundation of syntax? This study shows that great apes, like human adults but unlike infants, differentiate agents from patients in event roles, suggesting that event role apprehension predates language, emerging under ontogenetic processes. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Overall and central obesity and prostate cancer risk in African men

Author

Agalliu, Ilir, Lin, Wei-Kaung Jerry, Zhang, Janice S., Jacobson, Judith S., Rohan, Thomas E., Adusei, Ben, Snyper, Nana Yaa F., Andrews, Caroline, Sidahmed, Elkhansa, Mensah, James E., Biritwum, Richard, Adjei, Andrew A., Okyne, Victoria, Ainuson-Quampah, Joana, Fernandez, Pedro, Irusen, Hayley, Odiaka, Emeka, Folasire, Oluyemisi Folake, Ifeoluwa, Makinde Gabriel, Aisuodionoe-Shadrach, Oseremen I., Nwegbu, Maxwell Madueke, Pentz, Audrey, Chen, Wenlong Carl, Joffe, Maureen, Neugut, Alfred I., Diallo, Thierno Amadou, Jalloh, Mohamed, Rebbeck, Timothy R., Adebiyi, Akindele Olupelumi, and Hsing, Ann W.

Published
2022
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12. Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa

Author

Kim, Michelle S., Naidoo, Daphne, Hazra, Ujani, Quiver, Melanie H., Chen, Wenlong C., Simonti, Corinne N., Kachambwa, Paidamoyo, Harlemon, Maxine, Agalliu, Ilir, Baichoo, Shakuntala, Fernandez, Pedro, Hsing, Ann W., Jalloh, Mohamed, Gueye, Serigne M., Niang, Lamine, Diop, Halimatou, Ndoye, Medina, Snyper, Nana Yaa, Adusei, Ben, Mensah, James E., Abrahams, Afua O. D., Biritwum, Richard, Adjei, Andrew A., Adebiyi, Akindele O., Shittu, Olayiwola, Ogunbiyi, Olufemi, Adebayo, Sikiru, Aisuodionoe-Shadrach, Oseremen I., Nwegbu, Maxwell M., Ajibola, Hafees O., Oluwole, Olabode P., Jamda, Mustapha A., Singh, Elvira, Pentz, Audrey, Joffe, Maureen, Darst, Burcu F., Conti, David V., Haiman, Christopher A., Spies, Petrus V., van der Merwe, André, Rohan, Thomas E., Jacobson, Judith, Neugut, Alfred I., McBride, Jo, Andrews, Caroline, Petersen, Lindsay N., Rebbeck, Timothy R., and Lachance, Joseph

Published
2022
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14. Incremental sentence processing is guided by a preference for agents: EEG evidence from Basque

Author

Isasi-Isasmendi, Arrate; https://orcid.org/0000-0002-8574-8282, Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, Laka, Itziar; https://orcid.org/0000-0003-2402-2661, Meyer, Martin; https://orcid.org/0000-0003-2057-5533, Bickel, Balthasar; https://orcid.org/0000-0002-9087-0565, Isasi-Isasmendi, Arrate; https://orcid.org/0000-0002-8574-8282, Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, Laka, Itziar; https://orcid.org/0000-0003-2402-2661, Meyer, Martin; https://orcid.org/0000-0003-2057-5533, and Bickel, Balthasar; https://orcid.org/0000-0002-9087-0565

Abstract

Comprehenders across languages tend to interpret role-ambiguous arguments as the subject or the agent of a sentence during parsing. However, the evidence for such a subject/agent preference rests on the comprehension of transitive, active-voice sentences where agents/subjects canonically precede patients/objects. The evidence is thus potentially confounded by the canonical order of arguments. Transitive sentence stimuli additionally conflate the semantic agent role and the syntactic subject function. We resolve these two confounds in an experiment on the comprehension of intransitive sentences in Basque. When exposed to sentence-initial role-ambiguous arguments, comprehenders preferentially interpreted these as agents and had to revise their interpretation when the verb disambiguated to patient-initial readings. The revision was reflected in an N400 component in ERPs and a decrease in power in the alpha and lower beta bands. This finding suggests that sentence processing is guided by a top-down heuristic to interpret ambiguous arguments as agents, independently of word order and independently of transitivity.

Published
2024

15. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men

Author

Janivara, Rohini, primary, Hazra, Ujani, additional, Pfennig, Aaron, additional, Harlemon, Maxine, additional, Kim, Michelle S., additional, Eaaswarkhanth, Muthukrishnan, additional, Chen, Wenlong C., additional, Ogunbiyi, Adebola, additional, Kachambwa, Paidamoyo, additional, Petersen, Lindsay N., additional, Jalloh, Mohamed, additional, Mensah, James E., additional, Adjei, Andrew A., additional, Adusei, Ben, additional, Joffe, Maureen, additional, Gueye, Serigne M., additional, Aisuodionoe-Shadrach, Oseremen I., additional, Fernandez, Pedro W., additional, Rohan, Thomas E., additional, Andrews, Caroline, additional, Rebbeck, Timothy R., additional, Adebiyi, Akindele O., additional, Agalliu, Ilir, additional, and Lachance, Joseph, additional

Published
2024
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16. Primate origins of human event cognition

Author

Wilson, Vanessa A D, primary, Sauppe, Sebastian, additional, Brocard, Sarah, additional, Ringen, Erik Jacob, additional, Daum, Moritz M, additional, Wermelinger, Stephanie, additional, Gu, Nianlong, additional, Andrews, Caroline, additional, Isasi-Isasmendi, Arrate, additional, Bickel, Balthasar, additional, and Zuberbuehler, Klaus, additional

Published
2023
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17. Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial

Author

Scarborough, Matthew, Kamfose, Musa, de Veciana, Ana, Gordon, Nicola Claire, Peto, Leon, Pill, Gemma, Clarke, Tiphanie, Watson, Laura, Young, Bernadette, Griffiths, Dai, Vaughn, Ali, Anson, Luke, Liu, Elian, Perera, Sanuki, Rylance-Knight, Lydia, Cantell, Carmen, Moroney, Ruth, Edgeworth, Jonathan D, Thwaites, Guy, Bisnauthsing, Karen, Querol-Rubiera, Antonio, Gibbs, Charlotte, Patel, Amita, Hemsley, Carolyn, Goodman, Anna L, Wyncoll, Duncan, Biswas, Jason, Fitzpatrick, Jennifer, Roberts, Lizzie, Millard, James, Stone, Neil, Cape, Angela, Hurley, Lisa, Tam, Chi Kai, Nsutebu, Emmanuel, Hoyle, Marie-Claire, Maitland, Kate, Trainor, Leona, Reynolds, Helen, Harrison, Jennifer, Anson, Jim, Lewis, Joseph, Folb, Jonathan, Goodwin, Lynsey, Beeching, Nicholas, Dyas, Sarah, Winslow, Helen, Foote, Elizabeth, Roberts, Paul, Natarajan, Pavithra, Chrdle, Alex, Fenech, Manuel, Allsop, Hannah, Tilley, Robert, Austin-Hutchison, Rachel, Barrett, Louise, Brookes, Karen, Carwithen, Leanne, Conbeer, Andrew, Cunningham, Richard, Eglinton, Charlotte, Fok, Rosie, Gott, Hannah, Hughes, Shona, Jones, Lewis, Kalita, Maggie, King, Angela, March, Linda, Marner, Mike, Mynes, Tracey, Plant, Aiden, Price, Suzanne, Sercombe, Judy, Stolton, Alison, Wallis, Mark, West, Marie-Claire, Westcott, Jackie, Williams, Claire, Wosley, Rob, Yabsley, Leona, Greig, Julia, Butland, Laura, Sorrell, Julie, Mitchell, Tamara, Alli, Abiola, Meiring, James, Masake, Boingotlo, Rowson, Carlene, Smart, Lynne, Makey, Laura, Moll, Sarah, Cunningham, Jane, Ryalls, Kim, Birchall, Kathryn, Middle, Janet, Jackson, Yvonne, Swift, Diane, Cole, Joby, Subramanian, Bala, Okhuoya, Faith, Edwards, Maria, Bailey, Cheryl, Warren, Rebecca, Islam, Gayti, Ankcorn, Michael, Birchall, Sarah, Jones, Paul, Humphries, John, Booth, Stephen, Evan, Cariad, Wyllie, Sarah, Flatt, Andrew, Strakova, Lenka, Hayes, Maria, Valentine, Stacey, James, Clare, Wands, Mary, Cortes, Nicolas, Khan, Nisa, Porter, Robert, Martin, Zoe, Yip, Keith, Preedy, Helen, Chesterfield, Helen, Dobson, Tracey, Walker, Colin, Llewelyn, Martin, Dunne, Angela, Latter, Laura, Porges, Alison, Price, James, Paul, John, Behar, Laura, Robinson, Louise, Murray, Amy, Sargent, Tenessa, Ridley, Carrie, de Gordoa, Laura Ortiz-Ruiz, Gilliam, Deborah, McPherson, Carole, Matthews, Simon, Foreman, Emma, Jarghese, Rajesh, Beddoe, Alisha, Martin, Sebastien, Shaw, Sephora, Wlazly, Dominika, Cole, Maggie, Gihawi, Abraham, Cole, Kevin, Török, M Estée, Gouliouris, Theodore, Bedford, Luke, Saunderson, Rebecca B, Mariolis, Ilias, Bousfield, Rachel, Ramsay, Isobel, Greaves, Daniel, Aliyu, Sani, Cox, Kim, Mlemba, Lois, Whitehead, Lynne, Vyse, Naval, Bolton, Mark, Williams, John, Lambert, Pauline, Chadwick, David, Baillie, Kirsty, Cain, Martyn, Bellamy, Richard, Wong, Jason, Thompson, Jane, Vassallo, Helen, Skotnicka, Agnieszka, Boyce, Andrea, Donnelly, Anthony, Wilson, Peter, FitzGerald, Graham, Dean, Victoria, Warnes, Kristian, Reyes, Anna, Rahman, Saadia, Tsang, Lillian, Williams, Joanne, Morris-Jones, Stephen, Hopkins, Susan, Witness, Elen, Brady, Orla, Woodford, Elizabeth, Pettifer, Teresa, McCadden, Angela, Marks, Ben, Collier, Sophie, Mack, Damien, Warren, Simon, Brown, Colin, Lyons, Adrian, Taiyari, Sara, Mepham, Stephen, Sweeney, Anna, Brown, Li-An, Auckland, Cressida, Potter, Alison, Mandiza, Jess, Hough, Maxine, Williams, Sue, Renton, Caroline, Walters, Fiona, Nadolski, Maria, Evans, Andree, Tarrant, Polly, Curley, Katherine, Whiteley, Sophie, Halpin, Julia, Hutchings, Melanie, Todd, Shirley, Lohan, Christop, Chapter, Tamika, Folland, Emma, Colville, Alaric, Marden, Katy, Morgan, Marina, Porter, Rob, Baxter, Mel, Minton, Jane, Rippon, Sarah, Cevik, Muge, Chapman, Judith, Kemp, Tim, Vincent, Rachel, Osborne, Dave, Platt, Tracey, Calderwood, James, Cook, Bernadette, Bedford, Caroline, Galloway-Browne, Leanne, Abberley, Nadine, Attack, Kelly, Allen, Joanna, Lal, Pankaj, Harrison, Melanie, Stevenson, Sarah, Brooks, Carol, Harlow, Paula, Ewing, Jordan, Cooper, Shirley, Balancio-Tolentino, Roderick, O'Neil, Laura, Tagney, Rebecca, Shackcloth, Daniela, Planche, Tim, Fellows, James, Millett, Ruth, Studham, Jo, de Souza, Cherrelle, Howell, Geoffrey, Greaves, Hezron, Foncel, Ella, Kurup, Rahul, Briggs, Jack, Smith, Melody, Suarez, Cristina, Sorrentino, Giordana, Scobie, Antonia, Houston, Angela, Ahmad, Fozia, Breathnach, Aodhan, Chahuan, Rakhee, Wilkins, Katie, Guleri, Achyut, Waddington, Natalia, Sharma, Rashmi, Flegg, Peter, Kollipara, Veenu, Alam, Mazhar, Potter, Andrew, Donaldson, Stacey, Armer, Charlote, Frudd, Julie, Jeyaratnam, Dakshika, Joy, Manju, Mathews, Asha, Glass, Stephen K, Ajayi, Ayodele, Fife, Amanda, Qaiser, Saba, Sheehan, Sharon, Muñoz-Villaverde, Sergio, Yogo, Noah, De Abreu, Ines, Notcheva, Gaynor, Flanagan, Joanna, Watson, Cordelia, Sais, Efisia, Adedayo, Adetunji, Chu, Vicky, Shaw, Georgina, Graver, Michelle A, Palmer, Rebecca, Palmer, Donna, Haile, Senait, Gordon, Joanne, Mandar, Kirandip, Szypura, Weronika, Jenkins, Neil, Marange, Josephine, Shabangu, Vusumuzi, Moore, Katy, Lyons, Jill, Munang, Melinda, Sangombe, Mirriam, Moran, Ed, Hussain, Abid, Wiselka, Martin, Lewszuk, Adam, Batham, Sally, Ellis, Kate, Bahadur, Leila, White, Helena, Pareek, Manish, Sahota, Amandip, Coleman, Stephen, Pateman, Hilary, Kotecha, Atul, Sim, Christopher, Rosser, Andrew, Deane, Jill, Nendick, Richard, Aldridge, Catherine, Clarke, Anne, Wood, Michelle, Marshall, Adele, Stephenson, Lynsey, Matheson-Smith, Tracy, Sloss, John, Potts, Kathryn, Malkin, Joanne, Ftika, Lemonia, Raviprakash, Veena, Sutton, Julian, Malachira, Ahalya, Kean, Miranda, Criste, Kristine, Gladas, Kirsty, Andrews, Caroline, Hutchison, Clare, Adams, Ellen, Andrews, Janet, Romans, Belinda, Ridley, Nicola, Ekani, Melanie, Mitchell, Julie, Smith, Nicola, Clark, Tristan, Glover, Sarah, Reed, Robert, Yam, Tat, Burton, Holly, Said, Rasha, Harvey, David, Janvier, Amy, Jacob, Reni, Smalley, Chris, Fair, Alison, Lord, Susan, Ripalda, Kate, Wooldridge, Helen, Cotter, Luis, Cardoso, Gus, Strachan, Elaine, Kaler, Gagan, Mohamoodally, Adam, Lawrence, Emma, Prime, Zoe, Abrahams, Rachel, Price, David Ashley, Rigden, Lesley, Shewan, Laura, Cullen, Katherine, Emmerson, Ingrid, Martin, Karen, Wilson, Hesther, Higham, Charley, Taylor, Kathryn Louise, Ong, Edmund, Patel, Bijal, Bond, Helena, Gradwell, Janine, Widdrington, John, Graham, Clive, Thornthwaite, Sarah, Prentice, Scott, Poultney, Una, Crowther, Hannah, Fairlamb, Helen, Hetherington, Emily, Brewer, Chris, Banerjee, Suryabrata, Hamson, Clare, McSkeane, Anna, McWhinney, Paul, Sharratt, Paula, Thorpe, Joanne, Kimachia, Sue, Wilson, Helen, Jeffs, Benjamin, Masters, Leslie, Wilson, Jonathan, Platt, Judith, Burgess, Lisa, Chadwick, Paul, Jeans, Adam, Keatley, Claire, Moran, Amanda, Swann, Zoe, Pagett, Katherine, Peel, Alex, Howard, Jason, Meisner, Sarah, Maloney, Kate, Masdin, Avril, Wright, Louise, Barlow, Gavin, Crossman, Samantha, Lowthorpe, Vicki, Moore, Emma, Moss, Peter, Parkin, Angela, Wolstencroft, Adam, Warner, Bev, Tarbotton, Clare, Eyre, Alison, Anderson, Anne, Burdett, Tina, Driffill, Amy, Walker, Ann Sarah, Hudson, Fleur, Szubert, Alex, Cairns, Janet, Ward, Denise, Webb, Helen, Russell, Charlotte, Jackson, Brooke, Otiko, Damilola, Borg, Chiara, Masters, Lindsey, Islam, Zaheer, Díaz-Montaña, Carlos, Johnson, Debbie, Thwaites, Guy E, Szubert, Alexander, Wyllie, Sarah A, Armando, Gonzalez-Ruiz, Chadwick, Paul R, Gordon, N Claire, Price, David A, Nayar, Deepa, Török, M Estee, Llewelyn, Martin J, and Walker, A Sarah

Published
2018
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19. Mutations in a Human ROBO Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis

Author

Jen, Joanna C., Chan, Wai-Man, Bosley, Thomas M., Wan, Jijun, Carr, Janai R., Rüb, Udo, Shattuck, David, Salamon, Georges, Kudo, Lili C., Ou, Jing, Kansu, Tülay, al Dhalaan, Hesham, al Zayed, Zayed, MacDonald, David B., Stigsby, Bent, Plaitakis, Andreas, Dretakis, Emmanuel K., Gottlob, Irene, Pieh, Christina, Traboulsi, Elias I., Wang, Qing, Wang, Lejin, Andrews, Caroline, Yamada, Koki, Demer, Joseph L., Karim, Shaheen, Alger, Jeffry R., Geschwind, Daniel H., Deller, Thomas, Sicotte, Nancy L., Nelson, Stanley F., Baloh, Robert W., and Engle, Elizabeth C.

Published
2004

20. Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction

Author

Hoffmann, Thomas J, primary, Graff, Rebecca E, additional, Madduri, Ravi K, additional, Rodriguez, Alex A, additional, Cario, Clint L, additional, Feng, Karen, additional, Jiang, Yu, additional, Wang, Anqi, additional, Klein, Robert J, additional, Pierce, Brandon L, additional, Eggener, Scott, additional, Tong, Lin, additional, Blot, William, additional, Long, Jirong, additional, Rebbeck, Timothy, additional, Lachance, Joseph, additional, Andrews, Caroline, additional, Adebiyi, Akindele O, additional, Adusei, Ben, additional, Aisuodionoe-Shadrach, Oseremen I, additional, Fernandez, Pedro W, additional, Jalloh, Mohamed, additional, Janivara, Rohini, additional, Chen, Wenlong C, additional, Mensah, James E, additional, Agalliu, Ilir, additional, Berndt, Sonja I, additional, Shelley, John P, additional, Schaffer, Kerry, additional, Machiela, Mitchell J, additional, Freedman, Neal D, additional, Huang, Wen-Yi, additional, Li, Shengchao A, additional, Goodman, Phyllis J, additional, Till, Cathee, additional, Thompson, Ian, additional, Lilja, Hans, additional, Van Den Eeden, Stephen K, additional, Chanock, Stephen J, additional, Mosley, Jonathan D, additional, Conti, David V, additional, Haiman, Christopher A, additional, Justice, Amy C, additional, Kachuri, Linda, additional, and Witte, John S, additional

Published
2023
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21. Heterogeneous genetic architectures and evolutionary genomics of prostate cancer in Sub-Saharan Africa

Author

Rebbeck, Timothy, primary, Janivara, Rohini, additional, Chen, Wenlong, additional, Hazra, Ujani, additional, Baichoo, Shakuntala, additional, Agalliu, Ilir, additional, Kachambwa, Paidamoyo, additional, Simonti, Corinne, additional, Brown, Lyda, additional, Tambe, Saanika, additional, Kim, Michelle, additional, Harlemon, Maxine, additional, Jalloh, Mohamed, additional, Muzondiwa, Dillon, additional, Naidoo, Daphne, additional, Ajayi, Olabode, additional, Snyper, Nana, additional, Niang, Lamine, additional, Diop, Halimatou, additional, Ndoye, Medina, additional, Mensah, James, additional, Darkwa-Abrahams, Afua, additional, Biritwum, Richard, additional, Adjei, Andrew, additional, Adebiyi, Akindele, additional, Shittu, Olayiwola, additional, Ogunbiyi, Olufemi, additional, Adebayo, Sikiru, additional, Nwegbu, Maxwell, additional, Ajibola, Hafees, additional, Oluwole, Olabode, additional, Jamda, Mustapha, additional, Pentz, Audrey, additional, Haiman, Christopher, additional, Spies, Petrus, additional, Merwe, Andre Van der, additional, Cook, Michael, additional, Chanock, Stephen J., additional, Berndt, Sonja I., additional, Watya, Stephen, additional, Lubwama, Alex, additional, Muchengeti, Mazvita, additional, Doherty, Sean, additional, Smyth, Natalie, additional, Lounsbury, David, additional, Fortier, Brian, additional, Rohan, Thomas, additional, Jacobson, Judith, additional, Neugut, Alfred, additional, Hsing, Ann, additional, Gusev, Alexander, additional, Aisuodionoe-Shadrach, Oseremen, additional, Joffe, Maureen, additional, Adusei, Ben, additional, Gueye, Serigne, additional, Fernandez, Pedro, additional, McBride, Jo, additional, Andrews, Caroline, additional, Petersen, Lindsay, additional, and Lachance, Joseph, additional

Published
2023
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24. Experimental research in cross-linguistic psycholinguistics

Author

Sauppe, Sebastian, Andrews, Caroline, Norcliffe, Elisabeth, University of Zurich, Zufferey, Sandrine, and Gygax, Pascal

Subjects
cross, linguistic typology, 400 Language, language processing, 410 Linguistics, experiments, EVOL NCCR Evolving Language, eye tracking, 10104 Department of Comparative Language Science, 490 Other languages, ISLE Center for the Interdisciplinary Study of Language Evolution, EEG, 150 Psychology, psycholinguistics, linguistic
Published
2023
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26. The Agent Preference in Visual Event Apprehension

Author

Isasi-Isasmendi, Arrate, primary, Andrews, Caroline, additional, Flecken, Monique, additional, Laka, Itziar, additional, Daum, Moritz M., additional, Meyer, Martin, additional, Bickel, Balthasar, additional, and Sauppe, Sebastian, additional

Published
2023
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27. Experimental research in cross-linguistic psycholinguistics

Author

Zufferey, Sandrine; https://orcid.org/0000-0002-5403-6709, Gygax, Pascal; https://orcid.org/0000-0003-4151-8255, Zufferey, S ( Sandrine ), Gygax, P ( Pascal ), Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, Norcliffe, Elisabeth; https://orcid.org/0000-0001-8646-6474, Zufferey, Sandrine; https://orcid.org/0000-0002-5403-6709, Gygax, Pascal; https://orcid.org/0000-0003-4151-8255, Zufferey, S ( Sandrine ), Gygax, P ( Pascal ), Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, and Norcliffe, Elisabeth; https://orcid.org/0000-0001-8646-6474

Abstract

In recent years, the field of psycholinguistics has seen an increased focus on the study of typologically diverse languages. Expanding cross-linguistic coverage is critical to tease apart those aspects of language processing that are general to the architecture of the human language processing system compared to those that are fine-tuned to the properties of the specific language one speaks. In this chapter, we present an overview of research in this area and describe in detail the kinds of experimental methods that are employed, with a particular focus on methods and procedures that have been developed for undertaking research on language processing outside of more familiar lab-based settings.

Published
2023

28. The Agent Preference in Visual Event Apprehension

Author

Isasi-Isasmendi, Arrate; https://orcid.org/0000-0002-8574-8282, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, Flecken, Monique; https://orcid.org/0000-0002-6935-1840, Laka, Itziar; https://orcid.org/0000-0003-2402-2661, Daum, Moritz M; https://orcid.org/0000-0002-4032-4574, Meyer, Martin; https://orcid.org/0000-0003-2057-5533, Bickel, Balthasar; https://orcid.org/0000-0002-9087-0565, Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197, Isasi-Isasmendi, Arrate; https://orcid.org/0000-0002-8574-8282, Andrews, Caroline; https://orcid.org/0000-0001-8681-9823, Flecken, Monique; https://orcid.org/0000-0002-6935-1840, Laka, Itziar; https://orcid.org/0000-0003-2402-2661, Daum, Moritz M; https://orcid.org/0000-0002-4032-4574, Meyer, Martin; https://orcid.org/0000-0003-2057-5533, Bickel, Balthasar; https://orcid.org/0000-0002-9087-0565, and Sauppe, Sebastian; https://orcid.org/0000-0001-8670-8197

Abstract

A central aspect of human experience and communication is understanding events in terms of agent (“doer”) and patient (“undergoer” of action) roles. These event roles are rooted in general cognition and prominently encoded in language, with agents appearing as more salient and preferred over patients. An unresolved question is whether this preference for agents already operates during apprehension, that is, the earliest stage of event processing, and if so, whether the effect persists across different animacy configurations and task demands. Here we contrast event apprehension in two tasks and two languages that encode agents differently; Basque, a language that explicitly case-marks agents (‘ergative’), and Spanish, which does not mark agents. In two brief exposure experiments, native Basqueand Spanish speakers saw pictures for only 300 ms, and subsequently described them or answered probe questions about them. We compared eye fixations and behavioral correlates of event role extraction with Bayesian regression. Agents received more attention and were recognized better across languages and tasks. At the same time, language and task demands affected the attention to agents. Our findings show that a general preference for agents exists in event apprehension, but it can be modulated by task and language demands.

Published
2023

29. Incremental sentence processing is guided by a preference for agents: EEG evidence from Basque.

Author

Isasi-Isasmendi, Arrate, Sauppe, Sebastian, Andrews, Caroline, Laka, Itziar, Meyer, Martin, and Bickel, Balthasar

Subjects
BRAIN physiology, EVOKED potentials (Electrophysiology), SEMANTICS, PHONOLOGICAL awareness, NEURONS, COMPARATIVE grammar, DESCRIPTIVE statistics, RESEARCH funding
Abstract

Comprehenders across languages tend to interpret role-ambiguous arguments as the subject or the agent of a sentence during parsing. However, the evidence for such a subject/agent preference rests on the comprehension of transitive, active-voice sentences where agents/subjects canonically precede patients/objects. The evidence is thus potentially confounded by the canonical order of arguments. Transitive sentence stimuli additionally conflate the semantic agent role and the syntactic subject function. We resolve these two confounds in an experiment on the comprehension of intransitive sentences in Basque. When exposed to sentence-initial role-ambiguous arguments, comprehenders preferentially interpreted these as agents and had to revise their interpretation when the verb disambiguated to patient-initial readings. The revision was reflected in an N400 component in ERPs and a decrease in power in the alpha and lower beta bands. This finding suggests that sentence processing is guided by a top-down heuristic to interpret ambiguous arguments as agents, independently of word order and independently of transitivity. [ABSTRACT FROM AUTHOR]

Published
2024
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30. IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium

Author

Andrews, Caroline, primary, McLean, Mairi H., additional, Hixon, Julie A., additional, Pontejo, Sergio M., additional, Starr, Tregei, additional, Malo, Courtney, additional, Cam, Margaret, additional, Ridnour, Lisa, additional, Hickman, Heather, additional, Steele-Mortimer, Olivia, additional, Wink, David A., additional, Young, Howard A., additional, McVicar, Daniel W., additional, Li, Wenqing, additional, and Durum, Scott K., additional

Published
2023
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31. Abstract 3508: Association between clonal hematopoiesis and risk of prostate cancer in a large sample of African ancestry men

Author

Wang, Anqi, primary, Xu, Yili, additional, Sheng, Xin, additional, Hughley, Raymond, additional, Adusei, Ben, additional, Jalloh, Mohamed, additional, Gueye, Serigne Magueye, additional, Adjei, Andrew A, additional, Mensah, James, additional, Fernandez, Pedro W., additional, Adebiyi, Akin Olupelumi, additional, Aisuodionoe-Shadrach, Oseremen Inokhoife, additional, Petersen, Lindsay, additional, Joffe, Maureen, additional, Bensen, Jeannette T., additional, Mohler, James L., additional, Taylor, Jack A., additional, Butler, Eboneé N., additional, Ingles, Sue A., additional, Rybicki, Benjamin A., additional, Stanford, Janet L., additional, Zheng, Wei, additional, Berndt, Sonja I., additional, Huff, Chad D., additional, Lachance, Joseph, additional, Multigner, Luc, additional, Andrews, Caroline, additional, Rebbeck, Timothy R., additional, Brureau, Laurent, additional, Chanock, Stephen J., additional, de Smith, Adam, additional, Chen, Fei, additional, Darst, Burcu F., additional, Conti, David V., additional, and Haiman, Christopher A., additional

Published
2023
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32. Abstract 1182: Association of prostate cancer candidate genes with overall and aggressive prostate cancer in men of African ancestry

Author

Chen, Fei, primary, Darst, Burcu F., additional, Sheng, Xin, additional, Wang, Anqi, additional, Xu, Yili, additional, Hughley, Raymond, additional, Adusei, Ben, additional, Jalloh, Mohamed, additional, Gueye, Serigne Magueye, additional, Adjei, Andrew A., additional, Mensah, James, additional, Fernandez, Pedro W., additional, Adebiyi, Akindele O., additional, Aisuodionoe-Shadrach, Oseremen, additional, Petersen, Lindsay, additional, Joffe, Maureen, additional, McBride, Jo, additional, Bensen, Jeannette T., additional, Mohler, James L., additional, Taylor, Jack A., additional, Butler, Eboneé N., additional, Ingles, Sue A., additional, Rybicki, Benjamin A., additional, Stanford, Janet L., additional, Zheng, Wei, additional, Berndt, Sonja I., additional, Huff, Chad D., additional, Lachance, Joseph, additional, Multigner, Luc, additional, Andrews, Caroline, additional, Rebbeck, Timothy R., additional, Brureau, Laurent, additional, Chanock, Stephen J., additional, Conti, David V., additional, and Haiman, Christopher A., additional

Published
2023
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33. Table S4 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa

Author

Harlemon, Maxine, primary, Ajayi, Olabode, primary, Kachambwa, Paidamoyo, primary, Kim, Michelle S., primary, Simonti, Corinne N., primary, Quiver, Melanie H., primary, Petersen, Desiree C., primary, Mittal, Anuradha, primary, Fernandez, Pedro W., primary, Hsing, Ann W., primary, Baichoo, Shakuntala, primary, Agalliu, Ilir, primary, Jalloh, Mohamed, primary, Gueye, Serigne M., primary, Snyper, Nana Yaa F., primary, Adusei, Ben, primary, Mensah, James E., primary, Abrahams, Afua O.D., primary, Adebiyi, Akindele O., primary, Orunmuyi, Akin T., primary, Aisuodionoe-Shadrach, Oseremen I., primary, Nwegbu, Maxwell M., primary, Joffe, Maureen, primary, Chen, Wenlong C., primary, Irusen, Hayley, primary, Neugut, Alfred I., primary, Quintana, Yuri, primary, Seutloali, Moleboheng, primary, Fadipe, Mayowa B., primary, Warren, Christopher, primary, Woehrmann, Marcos H., primary, Zhang, Peng, primary, Ongaco, Chrissie M., primary, Mawhinney, Michelle, primary, McBride, Jo, primary, Andrews, Caroline V., primary, Adams, Marcia, primary, Pugh, Elizabeth, primary, Rebbeck, Timothy R., primary, Petersen, Lindsay N., primary, and Lachance, Joseph, primary

Published
2023
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34. Data from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa

Author

Harlemon, Maxine, primary, Ajayi, Olabode, primary, Kachambwa, Paidamoyo, primary, Kim, Michelle S., primary, Simonti, Corinne N., primary, Quiver, Melanie H., primary, Petersen, Desiree C., primary, Mittal, Anuradha, primary, Fernandez, Pedro W., primary, Hsing, Ann W., primary, Baichoo, Shakuntala, primary, Agalliu, Ilir, primary, Jalloh, Mohamed, primary, Gueye, Serigne M., primary, Snyper, Nana Yaa F., primary, Adusei, Ben, primary, Mensah, James E., primary, Abrahams, Afua O.D., primary, Adebiyi, Akindele O., primary, Orunmuyi, Akin T., primary, Aisuodionoe-Shadrach, Oseremen I., primary, Nwegbu, Maxwell M., primary, Joffe, Maureen, primary, Chen, Wenlong C., primary, Irusen, Hayley, primary, Neugut, Alfred I., primary, Quintana, Yuri, primary, Seutloali, Moleboheng, primary, Fadipe, Mayowa B., primary, Warren, Christopher, primary, Woehrmann, Marcos H., primary, Zhang, Peng, primary, Ongaco, Chrissie M., primary, Mawhinney, Michelle, primary, McBride, Jo, primary, Andrews, Caroline V., primary, Adams, Marcia, primary, Pugh, Elizabeth, primary, Rebbeck, Timothy R., primary, Petersen, Lindsay N., primary, and Lachance, Joseph, primary

Published
2023
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35. Figure S1 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa

Author

Harlemon, Maxine, primary, Ajayi, Olabode, primary, Kachambwa, Paidamoyo, primary, Kim, Michelle S., primary, Simonti, Corinne N., primary, Quiver, Melanie H., primary, Petersen, Desiree C., primary, Mittal, Anuradha, primary, Fernandez, Pedro W., primary, Hsing, Ann W., primary, Baichoo, Shakuntala, primary, Agalliu, Ilir, primary, Jalloh, Mohamed, primary, Gueye, Serigne M., primary, Snyper, Nana Yaa F., primary, Adusei, Ben, primary, Mensah, James E., primary, Abrahams, Afua O.D., primary, Adebiyi, Akindele O., primary, Orunmuyi, Akin T., primary, Aisuodionoe-Shadrach, Oseremen I., primary, Nwegbu, Maxwell M., primary, Joffe, Maureen, primary, Chen, Wenlong C., primary, Irusen, Hayley, primary, Neugut, Alfred I., primary, Quintana, Yuri, primary, Seutloali, Moleboheng, primary, Fadipe, Mayowa B., primary, Warren, Christopher, primary, Woehrmann, Marcos H., primary, Zhang, Peng, primary, Ongaco, Chrissie M., primary, Mawhinney, Michelle, primary, McBride, Jo, primary, Andrews, Caroline V., primary, Adams, Marcia, primary, Pugh, Elizabeth, primary, Rebbeck, Timothy R., primary, Petersen, Lindsay N., primary, and Lachance, Joseph, primary

Published
2023
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36. Erratum for Brothwell et al., “Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-Inflammatory Environment in the Human Host”

Author

Brothwell, Julie A., primary, Fortney, Kate R., additional, Gao, Hongyu, additional, Wilson, Landon S., additional, Andrews, Caroline F., additional, Tran, Tuan M., additional, Hu, Xin, additional, Batteiger, Teresa A., additional, Barnes, Stephen, additional, Liu, Yunlong, additional, and Spinola, Stanley M., additional

Published
2023
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37. The Agent Preference in Visual Event Apprehension

Author

Isasi-Isasmendi, Arrate, Andrews, Caroline, Flecken, Monique, Laka, Itziar, Daum, Moritz M, Meyer, Martin, Bickel, Balthasar, Sauppe, Sebastian, and University of Zurich

Subjects
Linguistics and Language, 10093 Institute of Psychology, 10104 Department of Comparative Language Science, 490 Other languages, Cognitive Neuroscience, Developmental and Educational Psychology, 410 Linguistics, ISLE Center for the Interdisciplinary Study of Language Evolution, Experimental and Cognitive Psychology, 890 Other literatures, 150 Psychology, EVOL NCCR Evolving Language
Abstract

A central aspect of human experience and communication is understanding events in terms of agent (“doer”) and patient (“undergoer” of action) roles. These event roles are rooted in general cognition and prominently encoded in language, with agents appearing as more salient and preferred over patients. An unresolved question is whether this preference for agents already operates during apprehension, that is, the earliest stage of event processing, and if so, whether the effect persists across different animacy configurations and task demands. Here we contrast event apprehension in two tasks and two languages that encode agents differently; Basque, a language that explicitly case-marks agents (‘ergative’), and Spanish, which does not mark agents. In two brief exposure experiments, native Basqueand Spanish speakers saw pictures for only 300 ms, and subsequently described them or answered probe questions about them. We compared eye fixations and behavioral correlates of event role extraction with Bayesian regression. Agents received more attention and were recognized better across languages and tasks. At the same time, language and task demands affected the attention to agents. Our findings show that a general preference for agents exists in event apprehension, but it can be modulated by task and language demands.

Published
2023
Full Text
View/download PDF

38. Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host

Author

Brothwell, Julie A., primary, Fortney, Kate R., additional, Gao, Hongyu, additional, Wilson, Landon S., additional, Andrews, Caroline F., additional, Tran, Tuan M., additional, Hu, Xin, additional, Batteiger, Teresa A., additional, Barnes, Stephen, additional, Liu, Yunlong, additional, and Spinola, Stanley M., additional

Published
2022
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44. A new argument for co-active parses during language comprehension

Author

Dillon, Brian, Andrews, Caroline, Rotello, Caren, and Wagers, Matthew

Subjects
computational modeling, Signal Detection, Psychological, parsing, Social and Behavioral Sciences, computer.software_genre, Language and Linguistics, Sentence processing, Psycholinguistics, syntactic ambiguity, Argument, Models, Psychology, ROC, signal detection theory, media_common, Parsing, 05 social sciences, Experimental Psychology, Ambiguity, Signal Detection, FOS: Psychology, Psycholinguistics and Neurolinguistics, Cognitive Sciences, Comprehension, Natural language processing, Sentence, Adult, Linguistics and Language, media_common.quotation_subject, Experimental and Cognitive Psychology, Models, Psychological, 050105 experimental psychology, Young Adult, Humans, 0501 psychology and cognitive sciences, psycholinguistics, business.industry, Linguistics, sentence processing, ROCs, Reading comprehension, ROC Curve, Reading, FOS: Languages and literature, sentence comprehension, Psychological, Artificial intelligence, business, computer
Abstract

One perennially important question for theories of sentence comprehension is whether the human sentence processing mechanism is parallel (i.e., it simultaneously represents multiple syntactic analyses of linguistic input) or serial (i.e., it constructs only a single analysis at a time). Despite its centrality, this question has proven difficult to address for both theoretical and methodological reasons (Gibson & Pearlmutter, 2000; Lewis, 2000). In the present study, we reassess this question from a novel perspective. We investigated the well-known ambiguity advantage effect (Traxler, Pickering, & Clifton, 1998) in a speeded acceptability judgment task. We adopted a signal detection theoretic approach to these data, with the goal of determining whether speeded judgment responses were conditioned on one or multiple syntactic analyses. To link these results to incremental parsing models, we developed formal models to quantitatively evaluate how serial and parallel parsing models should impact perceived sentence acceptability in our task. Our results suggest that speeded acceptability judgments are jointly conditioned on multiple parses of the input, a finding that is overall more consistent with parallel parsing models than serial models. Our study thus provides a new, psychophysical argument for coactive parses during language comprehension. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Published
2022
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46. A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry

Author

Darst, Burcu F., Hughley, Raymond, Pfennig, Aaron, Hazra, Ujani, Fan, Caoqi, Wan, Peggy, Sheng, Xin, Xia, Lucy, Andrews, Caroline, Chen, Fei, Berndt, Sonja I., Kote-Jarai, Zsofia, Govindasami, Koveela, Bensen, Jeannette T., Ingles, Sue A., Rybicki, Benjamin A., Nemesure, Barbara, John, Esther M., Fowke, Jay H., Huff, Chad D., Strom, Sara S., Isaacs, William B., Park, Jong Y., Zheng, Wei, Ostrander, Elaine A., Walsh, Patrick C., Carpten, John, Sellers, Thomas A., Yamoah, Kosj, Murphy, Adam B., Sanderson, Maureen, Crawford, Dana C., Gapstur, Susan M., Bush, William S., Aldrich, Melinda C., Cussenot, Olivier, Petrovics, Gyorgy, Cullen, Jennifer, Neslund-Dudas, Christine, Kittles, Rick A., Xu, Jianfeng, Stern, Mariana C., Chokkalingam, Anand P., Multigner, Luc, Parent, Marie-Elise, Menegaux, Florence, Cancel-Tassin, Geraldine, Kibel, Adam S., Klein, Eric A., Goodman, Phyllis J., Stanford, Janet L., Drake, Bettina F., Hu, Jennifer J., Clark, Peter E., Blanchet, Pascal, Casey, Graham, Hennis, Anselm J.M., Lubwama, Alexander, Thompson, Ian M., Jr, Leach, Robin J., Gundell, Susan M., Pooler, Loreall, Mohler, James L., Fontham, Elizabeth T.H., Smith, Gary J., Taylor, Jack A., Brureau, Laurent, Blot, William J., Biritwum, Richard, Tay, Evelyn, Truelove, Ann, Niwa, Shelley, Tettey, Yao, Varma, Rohit, McKean-Cowdin, Roberta, Torres, Mina, Jalloh, Mohamed, Magueye Gueye, Serigne, Niang, Lamine, Ogunbiyi, Olufemi, Oladimeji Idowu, Michael, Popoola, Olufemi, Adebiyi, Akindele O., Aisuodionoe-Shadrach, Oseremen I., Nwegbu, Maxwell, Adusei, Ben, Mante, Sunny, Darkwa-Abrahams, Afua, Yeboah, Edward D., Mensah, James E., Anthony Adjei, Andrew, Diop, Halimatou, Cook, Michael B., Chanock, Stephen J., Watya, Stephen, Eeles, Rosalind A., Chiang, Charleston W.K., Lachance, Joseph, Rebbeck, Timothy R., Conti, David V., and Haiman, Christopher A.

Published
2022
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47. Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

Author

Chen, Fei, primary, Darst, Burcu F, primary, Madduri, Ravi K, additional, Rodriguez, Alex A, additional, Sheng, Xin, additional, Rentsch, Christopher T, additional, Andrews, Caroline, additional, Tang, Wei, additional, Kibel, Adam S, additional, Plym, Anna, additional, Cho, Kelly, additional, Jalloh, Mohamed, additional, Gueye, Serigne Magueye, additional, Niang, Lamine, additional, Ogunbiyi, Olufemi J, additional, Popoola, Olufemi, additional, Adebiyi, Akindele O, additional, Aisuodionoe-Shadrach, Oseremen I, additional, Ajibola, Hafees O, additional, Jamda, Mustapha A, additional, Oluwole, Olabode P, additional, Nwegbu, Maxwell, additional, Adusei, Ben, additional, Mante, Sunny, additional, Darkwa-Abrahams, Afua, additional, Mensah, James E, additional, Adjei, Andrew Anthony, additional, Diop, Halimatou, additional, Lachance, Joseph, additional, Rebbeck, Timothy R, additional, Ambs, Stefan, additional, Gaziano, J Michael, additional, Justice, Amy C, additional, Conti, David V, additional, and Haiman, Christopher A, additional

Published
2022
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48. Author response: Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

Author

Chen, Fei, primary, Darst, Burcu F, primary, Madduri, Ravi K, additional, Rodriguez, Alex A, additional, Sheng, Xin, additional, Rentsch, Christopher T, additional, Andrews, Caroline, additional, Tang, Wei, additional, Kibel, Adam S, additional, Plym, Anna, additional, Cho, Kelly, additional, Jalloh, Mohamed, additional, Gueye, Serigne Magueye, additional, Niang, Lamine, additional, Ogunbiyi, Olufemi J, additional, Popoola, Olufemi, additional, Adebiyi, Akindele O, additional, Aisuodionoe-Shadrach, Oseremen I, additional, Ajibola, Hafees O, additional, Jamda, Mustapha A, additional, Oluwole, Olabode P, additional, Nwegbu, Maxwell, additional, Adusei, Ben, additional, Mante, Sunny, additional, Darkwa-Abrahams, Afua, additional, Mensah, James E, additional, Adjei, Andrew Anthony, additional, Diop, Halimatou, additional, Lachance, Joseph, additional, Rebbeck, Timothy R, additional, Ambs, Stefan, additional, Gaziano, J Michael, additional, Justice, Amy C, additional, Conti, David V, additional, and Haiman, Christopher A, additional

Published
2022
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49. Human CHN1 Mutations Hyperactivate α2-Chimaerin and Cause Duane's Retraction Syndrome

Author

Miyake, Noriko, Chilton, John, Psatha, Maria, Cheng, Long, Andrews, Caroline, Chan, Wai-Man, Law, Krystal, Crosier, Moira, Lindsay, Susan, Cheung, Michelle, Allen, James, Gutowski, Nick J., Ellard, Sian, Young, Elizabeth, Iannaccone, Alessandro, Appukuttan, Binoy, Stou, J. Timothy, Christiansen, Stephen, Ciccarelli, Maria Laura, Baldi, Altonso, Campioni, Mara, Zenteno, Juan C., Davenport, Dominic, Mariani, Laura E., Sahin, Mustafa, Guthrie, Sarah, and Engle, Elizabeth C.

Published
2008
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