Search

Your search keyword '"Angelopoulou, M. K."' showing total 192 results
Start Over Author "Angelopoulou, M. K."
192 results on '"Angelopoulou, M. K."'

1. Hematology-Cell Morphology - Case 26.

Author

Asimakopoulos, J. V., Papageorgiou, L., Drandakis, J., Vasilopoulos, I., Kopsaftopoulou, D., Piperidou, A., Machairas, A., Georgopoulou, A., Karapaschalidis, A., Lefaki, M. A., Liaskas, A., Zerzi, C., Plata, E., Tsaftaridis, P., Siakantaris, M. P., Vassilakopoulos, T. P., Angelopoulou, M. K., and Meletis, J.

Subjects
BONE marrow examination, LEUKOCYTES, GOLGI apparatus, ACID phosphatase, ACUTE myeloid leukemia
Abstract

The article "Hematology-Cell Morphology - Case 26" published in the Archives of Hellenic Medicine discusses acute lymphoblastic leukemia (ALL) with a focus on cell morphology. It highlights characteristics such as lymphoblast predominance, cytoplasmic features, and cytogenetic abnormalities. The text also delves into diagnostic criteria, including bone marrow examination and myelogram analysis. The article provides detailed descriptions of morphological features and staining techniques used in identifying and diagnosing ALL, specifically the L1 type. [Extracted from the article]

Published
2024

2. EVALUATION OF GONADAL FUNCTION IN YOUNG MEN AND WOMEN DIAGNOSED WITH HODGKIN LYMPHOMA

Author

Georgopoulou, A. N., primary, Vassilakopoulos, T. P., additional, Panayiotidis, P., additional, Siakantaris, M., additional, Keramaris, K., additional, Georgopoulos, N. A., additional, Kalantaridou, S., additional, Arapaki, M., additional, Chatzidimitriou, C., additional, Kopsaftopoulou, A., additional, Mamali, I., additional, and Angelopoulou, M. K., additional

Published
2023
Full Text
View/download PDF

3. EVALUATION OF FERTILITY IN WOMEN TREATED WITH THE R‐DA‐EPOCH REGIMEN FOR PRIMARY MEDIASTINAL B CELL LYMPHOMA (PMBCL)

Author

Georgopoulou, A. N., primary, Vassilakopoulos, T. P., additional, Kalantaridou, S., additional, Georgopoulos, N. A., additional, Lalou, E., additional, Panayiotidis, P., additional, Siakantaris, M., additional, Konstantinou, I., additional, Galopoulos, D., additional, Belia, M., additional, Piperidou, A., additional, and Angelopoulou, M. K., additional

Published
2023
Full Text
View/download PDF

4. PET/CT in primary mediastinal large B-cell lymphoma responding to rituximab-CHOP: An analysis of 106 patients regarding prognostic significance and implications for subsequent radiotherapy

Author

Vassilakopoulos, T P, Pangalis, G A, Chatziioannou, S, Papageorgiou, S, Angelopoulou, M K, Galani, Z, Kourti, G, Prassopoulos, V, Leonidopoulou, T, Terpos, E, Dimopoulou, M N, Sachanas, S, Kalpadakis, C, Konstantinidou, P, Boutsis, D, Stefanoudaki, E, Kyriazopoulou, L, Siakantaris, M P, Kyrtsonis, M-C, Variami, E, Kotsianidis, I, Symeonidis, A, Michali, E, Katodritou, E, Kokkini, G, Tsatalas, C, Papadaki, H, Dimopoulos, M-A, Sotiropoulos, V, Pappa, V, Karmiris, T, Meletis, J, Apostolidis, J, Datseris, I, Panayiotidis, P, Konstantopoulos, K, Roussou, P, and Rondogianni, P

Published
2016
Full Text
View/download PDF

5. P1085: EVALUATION OF GONADAL FUNCTION IN YOUNG WOMEN DIAGNOSED WITH HODGKIN AND NON-HODGKIN LYMPHOMA

Author

Georgopoulou, A. N., primary, Giannakou, A., additional, Vassilakopoulos, T. P., additional, Siakantaris, M., additional, Georgopoulos, N. A., additional, Kalantaridou, S., additional, Lalou, E., additional, Keramaris, K., additional, Loukari, E., additional, Arapaki, M., additional, Konstantinou, I., additional, Machairas, A., additional, Kopsaftopoulou, A., additional, Mammali, I., additional, Vassilopoulos, I., additional, Galopoulos, D., additional, and Angelopoulou, M. K., additional

Published
2022
Full Text
View/download PDF

8. A prospective, cohort, multicentre study of candidaemia in hospitalized adult patients with haematological malignancies

Author

Gamaletsou, M. N., Walsh, T. J., Zaoutis, T., Pagoni, M., Kotsopoulou, M., Voulgarelis, M., Panayiotidis, P., Vassilakopoulos, T., Angelopoulou, M. K., Marangos, M., Spyridonidis, A., Kofteridis, D., Pouli, A., Sotiropoulos, D., Matsouka, P., Argyropoulou, A., Perloretzou, S., Leckerman, K., Manaka, A., Oikonomopoulos, P., Daikos, G., Petrikkos, G., and Sipsas, N. V.

Published
2014
Full Text
View/download PDF

10. Hematology-Cell Morphology -- Case 16.

Author

Asimakopoulos, J. V., Papageorgiou, L., Drandakis, J., Vasilopoulos, I., Galopoulos, D., Kopsaftopoulou, A., Piperidou, A., Machairas, A., Georgopoulou, A., Karapaschalidis, A., Lefaki, M. A., Liaskas, A., Zerzi, C., Sinni, E., Plata, E., Tsaftaridis, P., Siakantaris, M. P., Vassilakopoulos, T. P., Angelopoulou, M. K., and Meletis, J.

Subjects
MORPHOLOGY, BONE marrow cells, EPSTEIN-Barr virus diseases
Published
2022

13. Hematology-Cell Morphology - Case 20.

Author

Asimakopoulos, J. V., Papageorgiou, L., Drandakis, J., Vasilopoulos, I., Galopoulos, D., Kopsaftopoulou, A., Piperidou, A., Machairas, A., Georgopoulou, A., Karapaschalidis, A., Lefaki, M. A., Liaskas, Î'., Zerzi, C., Sinni, E., Plata, E., Tsaftaridis, P., Siakantaris, M. P., Vassilakopoulos, T. P., Angelopoulou, M. K., and Meletis, J.

Subjects
MORPHOLOGY, BONE marrow cells
Published
2023

14. Hematology-Cell Morphology - Case 19.

Author

Asimakopoulos, J. V., Papageorgiou, L., Drandakis, J., Vasilopoulos, I., Galopoulos, D., Kopsaftopoulou, A., Piperidou, A., Machairas, A., Georgopoulou, A., Karapaschalidis, A., Lefaki, M. A., Liaskas, Î'., Zerzi, C., Sinni, E., Plata, E., Tsaftaridis, P., Siakantaris, M. P., Vassilakopoulos, T. P., Angelopoulou, M. K., and Meletis, J.

Subjects
MORPHOLOGY, BONE marrow cells
Published
2023

18. Hematology-Cell Morphology - Case 5.

Author

Asimakopoulos, J. V., Papageorgiou, L., Arapaki, P. M., Chatzidimitriou, C., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Drandakis, J., Machairas, A., Kopsaftopoulou, A., Panitsas, F., Benekou, K., Sinni, E., Siakantaris, M. P., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., and Angelopoulou, M. K.

Subjects
MORPHOLOGY, BONE marrow cells, BONE marrow transplantation
Published
2020

19. Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia

Author

Cornely, O. A., Leguay, T., Maertens, J., Vehreschild, M. J. G. T., Anagnostopoulos, A., Castagnola, C., Verga, L., Rieger, C., Kondakci, M., Harter, G., Duarte, R. F., Allione, B., Cordonnier, C., Heussel, C. P., Morrissey, C. O., Agrawal, S. G., Peter Donnelly, J., Bresnik, M., Hawkins, M. J., Garner, W., Gokbuget, N., Jarchum, G., Dictar, M., Ramirez Borga, S., Valledor, A., Knoebl, P., Greil, R., Linkesch, W., Sill, H., De Prijck, B., Sonet, A., Theunissen, K., Selleslag, D., Vargas Schwarzbold, A., Nucci, M. L. M., Lopes de Castro Lobo, C., Fogliatto, L., Bonmati, C., Turlure, P., Herbrecht, R., Thiebaut, A., Michallet, M., Egerer, G., Silling, G., Pfreundschuh, M., Hasenkamp, J., Kraemer, D. M., Topp, M., Heinz, W., Junghanss, C., Schaich, M. A., Parmentier, S., Roellig, C., Beck, H. J., Huttmann, A., Mousset, S., Duenzinger, U. N., Schwartz, S., Haerter, G., Ostermann, H., Tsirigotis, P., Matsouka, P., Angelopoulou, M. K., Karakantza, M., Spyridonidis, A., Kolomansky, A., Moses, A., Horowitz, N., Rahav, G., Aversa, F., Velardi, A., Pagano, Livio, Gentile, Giuseppe, Gobbi, M., Luppi, M., Nosari, A. M., Rambaldi, A., Candoni, A., Marbello, L., Rossi, G., Pogliani, E., Moreira, I., Nunes, A., Botelho de Sousa, A., Rubio Tejero, A. I., Vallejo, C., Vazquez, L., Besalduch Vidal, J., Gomez-Garcia de Soria, V., Jurado Chacon, M., Gonzalez Campos, J., Olavarria, E., Barba, P., de la Serna Torroba, J., Duarte, R., Heim, D., Zimmerli, S., Gerber, B., Akova, M., Bolaman, A. Z., Tabak, F., Akan, H., Senol, E., and Gilead Sciences

Subjects
0301 basic medicine, Male, Antifungal Agents, Administration, Intravenous, Adolescent, Adult, Aged, Aged, 80 and over, Amphotericin B, Chemoprevention, Double-Blind Method, Europe, Female, Humans, Invasive Fungal Infections, Middle Aged, Placebos, Precursor Cell Lymphoblastic Leukemia-Lymphoma, South America, Treatment Outcome, Young Adult, Medizin, law.invention, Randomized controlled trial, law, hemic and lymphatic diseases, Clinical endpoint, 80 and over, Pharmacology (medical), Original Research, hemic and immune systems, Chemotherapy regimen, Infectious Diseases, Tolerability, Administration, Intravenous, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Microbiology (medical), medicine.medical_specialty, 030106 microbiology, Neutropenia, Placebo, 03 medical and health sciences, Internal medicine, medicine, Pharmacology, Surrogate endpoint, business.industry, medicine.disease, Surgery, Regimen, Settore MED/15 - MALATTIE DEL SANGUE, business
Abstract

[Objectives] To prevent invasive fungal disease (IFD) in adult patients undergoing remission-induction chemotherapy for newly diagnosed acute lymphoblastic leukaemia (ALL)., [Patients and methods] In a double-blind multicentre Phase 3 study, patients received prophylactic liposomal amphotericin B (L-AMB) at 5 mg/kg intravenously or placebo twice weekly in a 2:1 random allocation during remission-induction treatment. The primary endpoint was the development of proven or probable IFD. Secondary endpoints included those focused on the safety and tolerability of prophylactic L-AMB., [Results] Three hundred and fifty-five patients from 86 centres in Europe and South America received at least one dose of L-AMB (n = 237) or placebo (n = 118). Rates of proven and probable IFD assessed independently were 7.9% (18/228) in the L-AMB group and 11.7% (13/111) in the placebo group (P = 0.24). Rates of possible IFD were 4.8% (11/228) in the L-AMB and 5.4% (6/111) in the placebo group (P = 0.82). The remission-induction phase was a median of 22 days for both groups. Overall mortality was similar between the groups: 7.2% (17/237) for L-AMB and 6.8% (8/118) for placebo (P = 1.00). Hypokalaemia and creatinine increase were significantly more frequent with L-AMB., [Conclusions] The IFD rate among adult patients undergoing remission-induction chemotherapy for newly diagnosed ALL was 11.7% in the placebo group, and was not significantly different in patients receiving L-AMB, suggesting that the L-AMB regimen studied is not effective as prophylaxis against IFD. The IFD rate appears higher than previously reported, warranting further investigation. Tolerability of L-AMB was what might be expected. Further studies are needed to determine the optimal antifungal strategy during remission-induction chemotherapy of ALL., This study was funded by Gilead Sciences, Inc. M. B., W. G. and M. J. H. are employees of Gilead Sciences. All other authors or their institutions have received compensation for study participation from Gilead Sciences International Ltd.

Published
2017

20. Hematology-Cell Morphology - Case 3.

Author

Asimakopoulos, J. V., Papageorgiou, L., Chatzidimitriou, C., Arapaki, P. M., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Pliakou, E., Drandakis, J., Machairas, A., Kopsaftopoulou, A., Benekou, K., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., and Konstantopoulos, K.

Subjects
MORPHOLOGY, BONE marrow transplantation
Published
2020

21. Hematology-Cell Morphology – Case 2.

Author

Asimakopoulos, J. V., Papageorgiou, L., Chatzidimitriou, C., Arapaki, P. M., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Pliakou, E., Drandakis, J., Machairas, A., Benekou, K., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
MORPHOLOGY, GOLGI apparatus, BONE marrow cells, BONE marrow transplantation
Published
2019

23. Hematology-Cell Morphology -- Case 6.

Author

Asimakopoulos, J. V., Papageorgiou, L., Arapaki, P. M., Chatzidimitriou, C., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Drandakis, J., Machairas, A., Kopsaftopoulou, A., Panitsas, F., Benekou, K., Sinni, E., Siakantaris, M. P., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., and Angelopoulou, M. K.

Subjects
MORPHOLOGY, CONTINUING medical education, BONE marrow transplantation
Published
2020

25. Hematology Quiz - Case 59.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Chatzidimitriou, C., Gainarou, G., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
BONE marrow transplantation, MEDICAL care
Published
2018

28. PET/CT in primary mediastinal large B-cell lymphoma responding to rituximab-CHOP: An analysis of 106 patients regarding prognostic significance and implications for subsequent radiotherapy

Author

Vassilakopoulos, T P, primary, Pangalis, G A, additional, Chatziioannou, S, additional, Papageorgiou, S, additional, Angelopoulou, M K, additional, Galani, Z, additional, Kourti, G, additional, Prassopoulos, V, additional, Leonidopoulou, T, additional, Terpos, E, additional, Dimopoulou, M N, additional, Sachanas, S, additional, Kalpadakis, C, additional, Konstantinidou, P, additional, Boutsis, D, additional, Stefanoudaki, E, additional, Kyriazopoulou, L, additional, Siakantaris, M P, additional, Kyrtsonis, M-C, additional, Variami, E, additional, Kotsianidis, I, additional, Symeonidis, A, additional, Michali, E, additional, Katodritou, E, additional, Kokkini, G, additional, Tsatalas, C, additional, Papadaki, H, additional, Dimopoulos, M-A, additional, Sotiropoulos, V, additional, Pappa, V, additional, Karmiris, T, additional, Meletis, J, additional, Apostolidis, J, additional, Datseris, I, additional, Panayiotidis, P, additional, Konstantopoulos, K, additional, Roussou, P, additional, and Rondogianni, P, additional

Published
2015
Full Text
View/download PDF

29. Pure infradiaphragmatic Hodgkin's lymphoma. Clinical features, prognostic factor and comparison with supradiaphragmatic disease

Author

Vassilakopoulos, T. P., Angelopoulou, M. K., Siakantaris, M. P., Konstantinou, N., Symeonidis, A., Karmiris, T., Repoussis, P., Roussou, P., Dimopoulos, A. M., Styliani Kokoris, Dimitriadou, E. M., Kyrtsonis, M. -C, Dimopoulou, M. N., Tsatalas, C., Kokkinis, G., Vrakidou, E., Grigoraki, V., Poziopoulos, C., Stamatellou, M., Liapis, D., Georgiou, G., Panayiotidis, P., and Pangalis, G. A.

Subjects
Treatment Outcome, Remission Induction, Humans, Prognosis, Hodgkin Disease, Survival Analysis
Abstract

Pure infradiaphragmatic Hodgkin's lymphoma (HL) is a rare disease. The prognostic impact of a purely infradiaphragmatic localization of this lymphoma is controversial. We aimed to evaluate the baseline clinicopathologic features, prognostic factors and outcome of a large series of consecutive patients with pure infradiaphragmatic HL.We analyzed 131 patients with clinical stage I/II infradiaphragmatic HL treated with ABVD or equivalent regimens with or without radiotherapy, and compared 54 of them with 444 patients with pure supradiaphragmatic disease, who were treated at the same center.Older age, clinical stage II (borderline), involvement ofor =3 sites, lymphocyte predominant histology, elevated serum beta2-microglobulin and higher International Prognostic Score were more frequent in patients with infradiaphragmatic disease than in those with supradiaphragmatic disease, while nodular sclerosis was less frequent. The complete remission rate was 100%, 97% and 82% for stages I, IIA and IIB, respectively. Only B-symptoms independently predicted for inferior failure-free survival, while inferior overall survival was independently associated with the involvement ofor =3 sites. At 10 years failure-free survival was 82+/-6% (vs. 85+/-2% for patients with supradiaphragmatic disease, p=0.45), overall survival was 74+/-8% (vs. 91+/-2%, p=0.0006), and disease-specific survival 87+/-5% (vs. 94+/-1%, p=0.04). In multivariate analysis the differences between infradiaphragmatic and supradiaphragmatic disease were obscured by older age and B-symptoms.Pure infradiaphragmatic HL presents with distinct clinicopathologic characteristics. The previously reported poorer outcome may be explained by the unfavorable profile of the patients rather than the infradiaphragmatic presentation per se. Patients with stage IIB disease should probably be classified as having advanced HL because of the unacceptable rate of primary refractory disease.

Published
2006

30. Hematology Quiz - Case 56.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Chatzidimitriou, C., Gainarou, G., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
HEMATOLOGY, ANEMIA, BONE marrow
Published
2017

32. Induction chemotherapy stategies for primary mediastinal large B-cell lymphoma with sclerosis: a retrospective multinational study on 426 previously untreated patients

Author

Zinzani, P. L., Martelli, Maurizio, Gianni, A. M., Devizzi, L., Federico, M., Pangalis, G., Michelis, J., Zucca, E., Cantonetti, M., Cortellazzo, S., Wotherspoon, A., Ferreri, A. J. M., Zaja, F., Lauria, F., DE RENZO, A., Liberati, M. A., Falini, B., Balzarotti, M., Calderoni, A., Zaccaria, A., Gentilini, P., Fattori, P. P., Pavone, E., Angelopoulou, M. K., Alinari, L., Brugiatelli, M., DI RENZO, N., Bonifazi, F., Pileri, S. A., and Cavalli, F.

Subjects
response rate, combined modality treatment, chemotherapy, PMLBCL, radiotherapy, PMLBCL, chemotherapy, radiotherapy, response rate, combined modality treatment
Published
2002

34. TREATMENT STRATEGIES AND PROGNOSTIC FACTORS FOR THE OUTCOME OF PATIENTS WITH HODGKIN LYMPHOMA EXPERIENCING VERY LATE RELAPSES AFTER CHEMOTHERAPY ± RADIOTHERAPY.

Author

Vassilakopoulos, T. P., Liaskas, A., Rizzuto, G., Symeonidis, A., Palma, M., Angelopoulou, M. K., Giatra, C., Spanoudakis, E., Oikonomopoulos, P., Kondopidou, F. N., Dimou, M., Musseti, A., Xagoraris, I., Siakantaris, M., Panitsas, F., Asimakopoulos, J., Arapaki, M., Chatzidimitriou, C., Belia, M., and Sachanas, S.

Subjects
HODGKIN'S disease, PROGNOSIS, RADIOTHERAPY
Abstract

TREATMENT STRATEGIES AND PROGNOSTIC FACTORS FOR THE OUTCOME OF PATIENTS WITH HODGKIN LYMPHOMA EXPERIENCING VERY LATE RELAPSES AFTER CHEMOTHERAPY ± RADIOTHERAPY B Conclusion: b The prognosis of VLRs does not appear very favorable, however a considerable proportion of patients were >=65 years old at the time of relapse when treatment options are limited and also, many patients succumb to disease-unrelated causes. B Background: b Despite the excellent long-term outcome of patients with Hodgkin Lymphoma (HL), some cases will be primary refractory or will eventually relapse, mainly within the first 2 years from diagnosis. [Extracted from the article]

Published
2023
Full Text
View/download PDF

35. Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib

Author

Georgiou, G, primary, Efthymiou, A, additional, Vardounioti, I, additional, Boutsikas, G, additional, Angelopoulou, M K, additional, Vassilakopoulos, T P, additional, Kyrtsonis, M-C, additional, Plata, E, additional, Tofas, P, additional, Bitsani, A, additional, Bartzi, V, additional, Pessach, I, additional, Dimou, M, additional, and Panayiotidis, P, additional

Published
2011
Full Text
View/download PDF

36. Paroxysmal nocturnal hemoglobinuria: From the molecular and biochemical defect to the clinical presentation.

Author

ASIMAKOPOULOS, J. V., PAPAGEORGIOU, L., KAMPOUROPOULOU, O., SAMARKOS, M., PLATA, E., VARIAMI, E., VASSILAKOPOULOS, T. P., TSAFTARIDIS, P., ANGELOPOULOU, M. K., KONSTANTOPOULOS, K., TERPOS, E., and MELETIS, J.

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) or Marchiafava-Micheli disease is an acquired clonal hematopoietic stem cell disorder that few clinicians or even hematologists have followed throughout its full natural history and clinical course. The molecular and biochemical background of PNH was elucidated at the end of the last century following nordecades of research. Over 180 somatic mutations of the X-linked gene PIG-A in hematopoietic stem cells have been implicated in the pathogenesis of PNH, resulting in impairment of the biosynthetic pathway of the glycosyl-phosphatidyl-inositol (GPI) molecule, which is a glycoprotein mechanism for membrane anchoring. PNH is the first and single example of acquired autoimmune hemolytic anemia with a negative Coombs' test. It is based on a red cell membrane defect with normal morphology, which leads to paroxysmal episodes of hemoglobinuria, with dark-coloured urine most noticeable in the morning. The red cell membrane deficiency of CD55 and CD59, GPI-anchored complement regulatory proteins, adequately explains the symptom of chronic intravascular hemolysis with hemosidirinuria, although the pathogenesis of thromboembolic events in unusual sites and bone marrow failure, which complement the characteristic clinical triad of PNH manifestations, still remains obscure. This review summarizes the available scientific elements of the unique molecular and biochemical defect of PNH and describes the underlying pathogenetic pathways that lead to its clinical manifestations. [ABSTRACT FROM AUTHOR]

Published
2015

37. Hematology Quiz − Case 57.

Author

Dryllis, G., Asimakopoulos, J. V., Stergiou, I., Chatzis, L., Papageorgiou, L., Arapaki, P. M., Giannikos, T., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Chatzidimitriou, C., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
HEMATOLOGY, MALARIA diagnosis
Published
2018

38. Hematology Quiz − Case 53.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Gainarou, G., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
JOINT pain, LYMPHADENITIS, DISEASES in men, HISTORY of medicine, BLOOD proteins
Published
2017

40. Hematology Quiz - Case 50.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Gainarou, G., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
JOINT pain
Abstract

The article presents a case study of a 48-year-old woman, who presented progressive anemia, small joints pain, and thrombocytopenia.

Published
2016

41. Hematology Quiz - Case 49.

Author

Papageorgiou, L., Asimakopoulos, J. V., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Nikolaou, E., Dryllis, G., Konstantinou, I., Benekou, A., Gainarou, G., Flevari, P., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
OUTPATIENT medical care, HEMATOLOGY
Abstract

The article presents the case study of a 44-year-old Greek sailor, who was presented to the outpatient department because of fever of one month's duration and fatigue and mentions results of hematological tests performed on the patient.

Published
2016

42. Hematology Quiz - Case 48.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Nikolaou, E., Dryllis, G., Konstantinou, I., Benekou, A., Gainarou, G., Flevari, P., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
LEUKEMIA, HEMATOLOGIC malignancies
Abstract

A Continuing Medical Education (CME) on acute monoblastic leukemia is presented.

Published
2016

43. Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients: Experience from a single hematology unit.

Author

Kyrtsonis, M.-C., Vassilakopoulos, T. P., Angelopoulou, M. K., Siakantaris, M. P., Kontopidou, F. N., Dimopoulou, M. N., Boussiotis, V., Gribabis, D. A., Konstantopoulos, K., Vaiopoulos, G. A., Fessas, P., Kittas, C., and Pangalis, G. A.

Subjects
BLOOD diseases, BLOOD hyperviscosity syndrome, PLASMA cells, SERUM, HYPERGAMMAGLOBULINEMIA, BONE marrow
Abstract

Waldenström's macroglobulinemia (WM) is a lymphoplasmacytic lymphoma characterized by the presence in patients' serum of an IgM monoclonal component. We report on our experience with 60 WM patients, focusing on their clinical findings, response to treatment, and the possible identification of prognostic factors. Of these patients, 70% presented with fatigue, and lymphadenopathy was observed in 22%, splenomegaly in 18%, hepatomegaly in 13%, and extranodal site of involvement in 6%. Bleeding tendency was seen in 17%, infections in 17%, hyperviscosity syndrome in 12%, and cardiac failure in 25% of the patients. The median of IgM levels was 30 g/l with hypoalbuminemia in 20% of cases, hypogammaglobulinemia in 27%, polyclonal hypergammaglobulinemia in 15%, kappa light-chain restriction in 78%, and Bence-Jones proteinuria in 54%. Anemia was frequent (85%), followed by leukocytosis (18%), lymphocytosis (12%), leukopenia (10%), and thrombocytopenia (10%). Cryoglobulinemia and autoimmune hemolytic anemia were encountered in 5%. In all cases but two, bone marrow was involved. Of 50 patients initially treated with intermittent oral chlorambucil, 46 (92%) responded. Median overall survival was 108 months. Factors associated with adverse prognosis were age ≥65 years (p=0.06), presence of lymphadenopathy (p=0.06), bone marrow infiltration ≥50% (p=0.007), international prognostic index (IPI) ≥3 (p=0.0001), and Morel's scoring system (p=0.04). Concluding, we found in this series of WM patients that chlorambucil is an effective treatment and that the parameters of age, lymphadenopathy, percentage of bone marrow infiltration, IPI, and Morel's scoring system carry prognostic significance. [ABSTRACT FROM AUTHOR]

Published
2001
Full Text
View/download PDF

44. Campath-1H in B-chronic lymphocytic leukemia: report on a patient treated thrice in a 3 year period.

Author

Pangalis, GA, Dimopoulou, MN, Angelopoulou, MK, Tsekouras, CH, Siakantaris, MP, Pangalis, G A, Dimopoulou, M N, Angelopoulou, M K, Tsekouras, C H, and Siakantaris, M P

Abstract

Monoclonal antibody (mAb) therapy is a novel alternative treatment for lymphoid malignancies. In this report we present a 55-year-old patient with B-chronic lymphocytic leukemia, who was initially treated with chlorambucil p.o. and subsequently with cyclophosphamide iv with poor response. Then Campath-1H mAb was administered. He received three cycles of Campath-1H, over a 3 yr period, lasting 12 weeks each, at a final dose of 30 mg weekly, on an outpatient basis. After each cycle of Campath-1H administration there was a significant decrease of the size of the palpable lymph nodes, spleen and liver. Restoration of the blood lymphocyte count to normal and a significant decrease of the bone marrow lymphocytic infiltration was observed at the end of each cycle. Therefore, a major clinical response was obtained after all cycles. Campath-1H administration was well tolerated without causing any serious toxicity. [ABSTRACT FROM AUTHOR]

Published
2000
Full Text
View/download PDF

45. Hematology Quiz − Case 46.

Author

Asimakopoulos, J. V., Papageorgiou, L., Telonis, V., Zannou, A., Arapaki, P. M., Giannikos, T., Dryllis, G., Konstantinou, I., Gainarou, G., Flevari, P., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
PLASMA cell leukemia, HEMATOLOGY, DIAGNOSIS
Abstract

A quiz concerning a patient with plasma cell leukemia presented with a history of bone pain in the lumbar area and no effect of non-steroidal anti-inflammatory drugs (NSAIDs) and diagnosis based on hematological tests is presented.

Published
2016

46. Hematology-Cell Morphology − Case 1.

Author

Asimakopoulos, J. V., Papageorgiou, L., Chatzidimitriou, C., Arapaki, P. M., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Pliakou, E., Drandakis, J., Sinni, E., Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Subjects
MORPHOLOGY, MEDICAL societies, BONE marrow transplantation
Published
2019

47. Hematology Quiz - Case 37.

Author

Vassilakopoulos, T. P., Petevi, K., Papageorgiou, L., Koutsi, E., Levidou, G., Gogoulou, I., Gainaru, G., Flevari, P., Boutsikas, G., Kanellopoulos, A., Telonis, V., Zannou, A., Tsaftaridis, P., Angelopoulou, M. K., Hanna, E., Konstantopoulos, K., Korkolopoulou, P., Plata, E., and Meletis, J.

Subjects
HEMATOLOGY, B cell lymphoma
Abstract

The article presents a quiz related to hematology and the author's views on diffuse large B-cell lymphoma (DLBCL).

Published
2014

48. Hematology Quiz - Case 37.

Author

Vassilakopoulos, T. P., Petevi, K., Papageorgiou, L., Koutsi, E., Levidou, G., Gogoulou, I., Gainaru, G., Flevari, P., Boutsikas, G., Kanellopoulos, A., Telonis, V., Zannou, A., Tsaftaridis, P., Angelopoulou, M. K., Hanna, E., Konstantopoulos, K., Korkolopoulou, P., Plata, E., and Meletis, J.

Subjects
BIOPSY, LYMPHOMAS
Abstract

The article describes the case of a 62-year-old male patient who was presented to a medical unit for further evaluation and treatment of a diffuse large B-cell lymphoma (DLBCL). Topics discussed include the symptoms presented by the patient, the findings of preoperative computed tomography (CT) imaging and the results of a liver biopsy conducted.

Published
2013

50. Hematology-cell morphology – case 3

Author

Asimakopoulos, J. V., Papageorgiou, L., Arapaki, P. M., Chatzidimitriou, C., Belia, M., Triantafyllou, E. F., Konstantinou, E., Efstathopoulou, M., Galopoulos, D., Pliakou, E., Drandakis, J., Machairas, A., Kopsaftopoulou, A., Benekou, K., Panitsas, F., Sinni, E., Marina Siakantaris, Tsaftaridis, P., Plata, E., Vassilakopoulos, T. P., Angelopoulou, M. K., Konstantopoulos, K., and Meletis, J.

Catalog

Books, media, physical & digital resources
See catalog results