4 results on '"Anne-Laure Lejeune"'
Search Results
2. Machine Learning and Deep Neural Network Applications in the Thorax
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Suonita Khung, Anne-Laure Lejeune, Antoine Hutt, Martine Remy-Jardin, Jessica Giordano, Rainer Kaergel, Paul Felloni, Jean-Baptiste Faivre, and Jacques Remy
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Pulmonary and Respiratory Medicine ,Thorax ,Hypertension, Pulmonary ,education ,Pulmonary disease ,030204 cardiovascular system & hematology ,Machine learning ,computer.software_genre ,030218 nuclear medicine & medical imaging ,Machine Learning ,Pulmonary Disease, Chronic Obstructive ,03 medical and health sciences ,0302 clinical medicine ,Daily practice ,medicine.artery ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Aorta ,business.industry ,medicine.disease ,Aortic Aneurysm ,Pulmonary embolism ,Chronic Disease ,Radiographic Image Interpretation, Computer-Assisted ,Chronic thromboembolic pulmonary hypertension ,Neural Networks, Computer ,Artificial intelligence ,Pulmonary Embolism ,Tomography, X-Ray Computed ,business ,computer - Abstract
The radiologic community is rapidly integrating a revolution that has not fully entered daily practice. It necessitates a close collaboration between computer scientists and radiologists to move from concepts to practical applications. This article reviews the current littérature on machine learning and deep neural network applications in the field of pulmonary embolism, chronic thromboembolic pulmonary hypertension, aorta, and chronic obstructive pulmonary disease.
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- 2020
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3. Systemic Pulmonary Events Associated with Myelodysplastic Syndromes: A Retrospective Multicentre Study
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Anne-Laure Lejeune, Louis Terriou, D. Launay, Lidwine Stervinou-Wemeau, Quentin Scanvion, Arsène Mekinian, Laurent Pascal, Valérie Deken, Bruno Quesnel, Eric Hachulla, Thierno Sy, CHU Lille, CNRS, Inserm, Université de Lille, Université Lille Nord (France), METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694, Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286, Hôpital Saint Vincent de Paul de Lille, Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277, Service de Pneumologie et Immuno-Allergologie [CHU LIlle], Centre Hospitalier Régional Universitaire [Lille] [CHRU Lille], Miniaturisation pour la Synthèse, l'Analyse et la Protéomique (MSAP) - USR 3290, and CHU Saint-Antoine [AP-HP]
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medicine.medical_specialty ,pulmonary alveolar proteinosis ,Population ,lcsh:Medicine ,Context (language use) ,[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,Article ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,pulmonary hypertension ,medicine ,pneumonia ,10. No inequality ,education ,030304 developmental biology ,interstitial lung disease ,0303 health sciences ,education.field_of_study ,Lung ,business.industry ,lcsh:R ,Interstitial lung disease ,Retrospective cohort study ,[SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology ,General Medicine ,medicine.disease ,Pulmonary hypertension ,3. Good health ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Cohort ,iatrogenic effects ,pleuritic effusion ,business ,Pulmonary alveolar proteinosis - Abstract
Although pulmonary events are considered to be frequently associated with malignant haemopathies, they have been sparsely studied in the specific context of myelodysplastic syndromes (MDS). We aimed to describe their different types, their relative proportions and their relative effects on overall survival (OS). We conducted a multicentre retrospective cohort study. Patients with MDS (diagnosed according to the 2016 WHO classification) and pulmonary events were included. The inclusion period was 1 January 2007 to 31 December 2017 and patients were monitored until August 2019. Fifty-five hospitalized patients were included in the analysis. They had 113 separate pulmonary events. Thirteen patients (23.6%) had a systemic autoimmune disease associated with MDS. Median age at diagnosis of MDS was 77 years. Median time to onset of pulmonary events was 13 months. Pulmonary events comprised: 70 infectious diseases (62%), 27 interstitial lung diseases (23.9%), including 13 non-specific interstitial pneumonias and seven secondary organizing pneumonias or respiratory bronchiolitis–interstitial lung diseases, 10 pleural effusions (8.8%), including four cases of chronic organizing pleuritis with exudative effusion, and six pulmonary hypertensions (5.3%). The median OS of the cohort was 29 months after MDS diagnosis but OS was only 10 months after a pulmonary event. The OS was similar to that of the general myelodysplastic population. However, the occurrence of a pulmonary event appeared to be either an accelerating factor of death or an indicator for the worsening of the underlying MDS in our study. More than a third of pulmonary events were non-infectious and could be systemic manifestations of MDS.
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- 2021
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4. Panton-Valentine Leukocidin–Secreting Staphylococcus aureus Pneumonia Complicating COVID-19
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Rémi Le Guern, Sophie Six, Caroline Loïez, Claire Tinez, Anne-Laure Lejeune, Frédéric Wallet, Claire Duployez, Laurent Robriquet, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Institut de Microbiologie [CHRU Lille], Pôle de Biologie Pathologie Génétique [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), and Le Guern, Rémi
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Male ,Epidemiology ,Expedited ,viruses ,lcsh:Medicine ,Cefotaxime ,medicine.disease_cause ,[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,chemistry.chemical_compound ,COVID-19 Testing ,Fatal Outcome ,0302 clinical medicine ,Leukocidins ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Pneumonia, Staphylococcal ,Spiramycin ,030212 general & internal medicine ,bacteria ,Coronavirus ,[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,Clindamycin ,virus diseases ,respiratory system ,Anti-Bacterial Agents ,3. Good health ,Panton-Valentine leukocidin ,Infectious Diseases ,coronavirus disease ,Staphylococcus aureus ,Superinfection ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Coronavirus Infections ,medicine.drug ,severe acute respiratory syndrome coronavirus 2 ,Adult ,Microbiology (medical) ,Bacterial Toxins ,Pneumonia, Viral ,030231 tropical medicine ,Exotoxins ,Microbiology ,lcsh:Infectious and parasitic diseases ,Betacoronavirus ,Necrosis ,03 medical and health sciences ,Metronidazole ,Research Letter ,medicine ,Humans ,lcsh:RC109-216 ,Pandemics ,Clinical Laboratory Techniques ,business.industry ,SARS-CoV-2 ,lcsh:R ,Linezolid ,COVID-19 ,biochemical phenomena, metabolism, and nutrition ,medicine.disease ,bacterial infections and mycoses ,Respiration, Artificial ,Pneumonia ,chemistry ,SARS-CoV3 ,[SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,necrotizing pneumonia ,Panton–Valentine leukocidin ,Panton-Valentine Leukocidin–Secreting Staphylococcus aureus Pneumonia COVID-19 ,Tomography, X-Ray Computed ,business - Abstract
International audience; Necrotizing pneumonia induced by Panton-Valentine leukocidin–secreting Staphylococcus aureus is a rare but life-threatening infection that has been described in patients after they had influenza. We report a fatal case of this superinfection in a young adult who had coronavirus disease.
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- 2020
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