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2. Pharmacological cAMP stimulation via prostaglandin receptors rescues ciliary defects in CEP290-deficient human and mouse models

3. A genotype-to-phenotype approach suggest under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project

4. Supplementary Data from Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA

7. Agonists of prostaglandin E 2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies

8. The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

10. Prostaglandin E1 as therapeutic molecule for Nephronophthisis and related ciliopathies

11. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

12. X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

18. Abstract 2428: Translational study of F14512, a novel vectorised epipodophyllotoxin, which demonstrates a marked activity on ovarian cancer models from patients

20. Abstract 1219: Patient-derived tumor models of resistant metastatic melanoma

22. Abstract 988: F14512, a novel vectorized topoiserase II inhibitor, bypasses MDR1 mediated resistance.

23. Abstract 5565: Tumor targeting and enhanced efficacy of novel polyamine-cytotoxic conjugates.

26. Melanoma Chemotherapy Leads to the Selection of ABCB5-Expressing Cells

27. Abstract A51: Antiproliferative activity of F14512, a novel polyamine-vectorized drug, on multidrug resistant cancer cells

28. Abstract 2747: Synergistic antileukemic activity of F14512 in combination with AraC

29. Abstract 1925: Trifluoromethylated artemisinin dimers demonstrate a potent anti-cancer activity in vitro and in vivo

30. Abstract A214: F14512, a novel targeted cytotoxic agent exhibits a marked antileukemic activity, alone and in combination with AraC.

31. Abstract 3518: In vitro and in vivo synergistic effects of F14512, a novel targeted cytotoxic agent in phase I clinical study, in combination with other anticancer drugs

32. Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma models

33. Abstract 5461: Novel antitumor amino-pancratistatin derivatives inhibitors of protein and DNA synthesis

34. Abstract A87: Synthesis and structure‐activity relationships of a series of epipodophyllotoxin polyamine conjugated derivatives vectorized for active polyamine transporter system in tumor cells, leading to the selection of F14512 for clinical trials

35. Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA

36. Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase

37. F14512, a Potent Antitumor Agent Targeting Topoisomerase II Vectored into Cancer Cells via the Polyamine Transport System

40. Principal expression of two mRNA isoforms (ABCB 5αandABCB 5β) of the ATP-binding cassette transporter geneABCB 5 in melanoma cells and melanocytes

41. Analysis of ATP-Binding Cassette Transporter Expression in Drug-Selected Cell Lines by a Microarray Dedicated to Multidrug Resistance

47. Principal expression of two mRNA isoforms (ABCB 5α andABCB 5β ).

48. Predicting drug sensitivity and resistance Profiling ABC transporter genes in cancer cells

49. A genotype-to-phenotype approach suggests under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project).

50. Different roles for K+ channels in cisplatin-resistant cell lines argue against a critical role for these channels in cisplatin resistance.

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