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9 results on '"Annese, Anita"'

1. The influence of invasive jellyfish blooms on the aquatic microbiome in a coastal lagoon (Varano, SE Italy) detected by an Illumina-based deep sequencing strategy

Author

Manzari, Caterina, Fosso, Bruno, Marzano, Marinella, Annese, Anita, Caprioli, Rosa, D’Erchia, Anna Maria, Gissi, Carmela, Intranuovo, Marianna, Picardi, Ernesto, Santamaria, Monica, Scorrano, Simonetta, Sgaramella, Giuseppe, Stabili, Loredana, Piraino, Stefano, and Pesole, Graziano

Published
2015
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2. Analysis of coding and non-coding transcriptome of peripheral B cells reveals an altered interferon response factor (IRF)-1 pathway in multiple sclerosis patients

Author

Annibali, Viviana, primary, Umeton, Renato, additional, Palermo, Antonia, additional, Severa, Martina, additional, Etna, Marilena Paola, additional, Giglio, Simona, additional, Romano, Silvia, additional, Ferraldeschi, Michela, additional, Buscarinu, Maria Chiara, additional, Vecchione, Andrea, additional, Annese, Anita, additional, Policano, Claudia, additional, Mechelli, Rosella, additional, Pizzolato Umeton, Raffaella, additional, Fornasiero, Arianna, additional, Angelini, Daniela Francesca, additional, Guerrera, Gisella, additional, Battistini, Luca, additional, Coccia, Eliana Marina, additional, Salvetti, Marco, additional, and Ristori, Giovanni, additional

Published
2018
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3. Whole transcriptome profiling of Late-Onset Alzheimer’s Disease patients provides insights into the molecular changes involved in the disease

Author

Annese, Anita, primary, Manzari, Caterina, additional, Lionetti, Claudia, additional, Picardi, Ernesto, additional, Horner, David S., additional, Chiara, Matteo, additional, Caratozzolo, Mariano Francesco, additional, Tullo, Apollonia, additional, Fosso, Bruno, additional, Pesole, Graziano, additional, and D’Erchia, Anna Maria, additional

Published
2018
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5. The influence of invasive jellyfish blooms on the aquatic microbiome in a coastal lagoon (Varano, SE Italy) detected by an Illumina-based deep sequencing strategy

Author

Manzari, Caterina, primary, Fosso, Bruno, additional, Marzano, Marinella, additional, Annese, Anita, additional, Caprioli, Rosa, additional, D’Erchia, Anna Maria, additional, Gissi, Carmela, additional, Intranuovo, Marianna, additional, Picardi, Ernesto, additional, Santamaria, Monica, additional, Scorrano, Simonetta, additional, Sgaramella, Giuseppe, additional, Stabili, Loredana, additional, Piraino, Stefano, additional, and Pesole, Graziano, additional

Published
2014
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6. Characterization of Epstein–Barr virus genotypes in multiple sclerosis through next generation sequencing approaches

Author

Coarelli, Giulia, primary, Manzari, Caterina, additional, Annese, Anita, additional, Anastasiadou, Eleni, additional, Policano, Claudia, additional, D'erchia, Anna Maria, additional, Picardi, Ernesto, additional, Buscarinu, Maria Chiara, additional, Annibali, Viviana, additional, Ricigliano, Vito Ag, additional, Tullo, Antonia, additional, Trivedi, Pankaj, additional, Pesole, Graziano, additional, Ristori, Giovanni, additional, Salvetti, Marco, additional, and Mechelli, Rosella, additional

Published
2014
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7. B cell IRF1 pathway is dysregulated in multiple sclerosis

Author

Annibali, Viviana, primary, Umeton, Renato, additional, Palermo, Antonia, additional, Buscarinu, Maria Chiara, additional, Policano, Claudia, additional, Mechelli, Rosella, additional, Romano, Silvia, additional, Angelini, Daniela F., additional, Piras, Eleonora, additional, Mattei, Gianluca, additional, Ricigliano, Vito Antonio Gerardo, additional, Annese, Anita, additional, Battistini, Luca, additional, Salvetti, Marco, additional, and Ristori, Giovanni, additional

Published
2014
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8. Epstein-Barr virus genetic variants are associated with multiple sclerosis.

Author

Mechelli, Rosella, Manzari, Caterina, Policano, Claudia, Annese, Anita, Picardi, Ernesto, Umeton, Renato, Fornasiero, Arianna, D'Erchia, Anna Maria, Buscarinu, Maria Chiara, Agliardi, Cristina, Annibali, Viviana, Serafini, Barbara, Rosicarelli, Barbara, Romano, Silvia, Angelini, Daniela F, Ricigliano, Vito A G, Buttari, Fabio, Battistini, Luca, Centonze, Diego, and Guerini, Franca R

Published
2015
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9. Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease

Author

Khermesh, Khen, D'Erchia, Anna Maria, Barak, Michal, Annese, Anita, Wachtel, Chaim, Levanon, Erez Y., Picardi, Ernesto, and Eisenberg, Eli

Abstract

Adenosine to inosine (A-to-I) RNA editing, catalyzed by the ADAR enzyme family, acts on dsRNA structures within pre-mRNA molecules. Editing of the coding part of the mRNA may lead to recoding, amino acid substitution in the resulting protein, possibly modifying its biochemical and biophysical properties. Altered RNA editing patterns have been observed in various neurological pathologies. Here, we present a comprehensive study of recoding by RNA editing in Alzheimer's disease (AD), the most common cause of irreversible dementia. We have used a targeted resequencing approach supplemented by a microfluidic-based high-throughput PCR coupled with next-generation sequencing to accurately quantify A-to-I RNA editing levels in a preselected set of target sites, mostly located within the coding sequence of synaptic genes. Overall, editing levels decreased in AD patients’ brain tissues, mainly in the hippocampus and to a lesser degree in the temporal and frontal lobes. Differential RNA editing levels were observed in 35 target sites within 22 genes. These results may shed light on a possible association between the neurodegenerative processes typical for AD and deficient RNA editing.

Published
2016
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