3,184 results on '"Anomia"'
Search Results
2. Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia
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National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute on Aging (NIA), Johns Hopkins University, and Aaron Meyer, PhD, Assistant Professor
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- 2024
3. Inner Speech and Naming Treatment for Individuals with Aphasia
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Mackenzie Fama, Assistant Professor
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- 2024
4. Treating Civilian Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation (ciTBI-HDtDCS)
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National Institute on Deafness and Other Communication Disorders (NIDCD) and John Hart, Jr., Professor
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- 2024
5. Lexical retrieval difficulties in post‐COVID‐19 syndrome: Insights from verbal fluency and naming tasks.
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González‐Nosti, María, Barrenechea, Arrate, Miguel‐Abella, Romina San, Pérez‐Sánchez, María del Carmen, Fernández‐Manzano, Lucía, Ramírez‐Arjona, Ainhoa, Rodríguez‐Pérez, Noelia, and Herrera, Elena
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ANOMIA , *DATA analysis , *POST-acute COVID-19 syndrome , *PHONOLOGICAL awareness , *QUESTIONNAIRES , *KRUSKAL-Wallis Test , *AGE distribution , *REVERSE transcriptase polymerase chain reaction , *DESCRIPTIVE statistics , *MANN Whitney U Test , *PSYCHOLINGUISTICS , *LANGUAGE disorders , *RESEARCH methodology , *COGNITION disorders , *NEUROPSYCHOLOGICAL tests , *ANALYSIS of variance , *STATISTICS , *SEMANTICS , *PHONETICS , *DATA analysis software , *VERBAL behavior , *EDUCATIONAL attainment , *LANGUAGE acquisition , *NONPARAMETRIC statistics , *DISEASE complications - Abstract
Background: Although considerable research has been conducted on post‐COVID‐19 syndrome (PCS), cognitive symptoms, particularly those related to language, are still not well understood. Aims: To provide a detailed quantitative and qualitative analysis of language performance in PCS patients using a comprehensive set of semantic and verbal production tasks. Methods & Procedures: The study involved 195 PCS patients aged 26–64 years and 50 healthy controls aged 25–61 years. Participants were assessed using two semantic tasks, three naming tasks and four types of verbal fluency tasks, designed to evaluate different aspects of language processing. Outcomes & Results: PCS patients demonstrated significantly poorer performance compared with controls across all verbal fluency tasks. This was evident in both the total number of words generated and their types, with patients tending to choose more easily accessible words. In naming tasks, the pattern of errors was similar in both groups, although patients showed a higher number of non‐responses and made more errors, reflecting difficulties in word retrieval. The analysis highlighted the impact of factors such as stimulus availability, educational level and cognitive reserve on performance. Notably, younger patients performed worse than older, a paradoxical trend also observed in previous research. Conclusions & Implications: These findings reveal significant word retrieval difficulties in PCS patients, suggesting that cognitive impairment related to language may be more pronounced than previously understood. The results underscore the need for a thorough evaluation of language functions in PCS patients and the development of more targeted and individualized language rehabilitation strategies to address these specific challenges. WHAT THIS PAPER ADDS: What is already known on the subject: Studies on the cognitive characteristics of CPS have focused mainly on broad‐spectrum neuropsychological assessments covering all cognitive functions. However, there are very few studies analysing oral production with specific lexical and semantic system tasks. Furthermore, no work has specifically included tasks assessing semantic processing or conducted qualitative analyses of the psycholinguistic variables affecting performance. Such analyses could undoubtedly help clarify the nature of the language impairments in patients with PCS. What this paper adds to the existing knowledge: This study explores in depth the evaluation and analysis of the oral production of patients with PCS using several lexical and semantic tasks. In addition, psycholinguistic variables are analysed that could undoubtedly help clarify the nature of the language impairments in patients with PCS. What are the potential or actual clinical implications of this work?: The study allows the identification of specific lexical–semantic deficits in the spoken language in patients with this PCS. A more detailed assessment of the oral language of these patients, keeping in mind the psycholinguistic variables that may affect the performance, will facilitate the design of more efficient and individualized rehabilitation programmes. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Effectiveness of French Phonological Components Analysis in individuals with chronic aphasia.
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Masson‐Trottier, Michèle, Marcotte, Karine, Rochon, Elizabeth, Leonard, Carol, and Ansaldo, Ana Inés
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LANGUAGE & languages , *COMMUNICATIVE competence , *MEDICAL protocols , *ANOMIA , *DATA analysis , *RESEARCH funding , *APHASIA , *TREATMENT effectiveness , *DESCRIPTIVE statistics , *STRUCTURAL equation modeling , *CHRONIC diseases , *APRAXIA , *PRE-tests & post-tests , *EXPERIMENTAL design , *STATISTICS , *ANALYSIS of variance , *RESEARCH methodology , *CONVALESCENCE , *PHONETICS , *DATA analysis software , *SPEECH therapy , *REGRESSION analysis - Abstract
Background: Over 50% of individuals with aphasia face ongoing word‐finding issues. Studies have found phonologically oriented therapy helpful for English speakers, but this has not yet been studied in French. It is essential to assess the effectiveness of such a therapy in French, considering the distinct linguistic typologies between both languages, which may impact the outcomes of phonologically oriented interventions. Aim: This paper evaluates the effectiveness of French Phonological Component Analysis (Fr‐PCA) on communication skills of individuals with chronic aphasia and the impact of individual factors on treatment success. Methods & Procedures: Eighteen individuals with chronic aphasia received 15 h of Fr‐PCA therapy over 5 weeks. Naming accuracy for treated and untreated words was measured before and after therapy, as well as at 3‐ and 6‐month follow‐ups. Secondary outcome measures included standardized tests measuring within‐level generalization (object and action naming) and across‐level generalization (repetition, verbal fluency, oral comprehension, communication effectiveness reported by a frequent communication partner). Outcomes & Results: Fr‐PCA led to improved accuracy for treated (17 participants out of 18) and untreated words (9 participants out of 18), with gains maintained at 6‐month follow‐up (7 participants out of 10 for treated and 6 participants out of 10 for untreated), and generalization to communication effectiveness reported by a frequent communication partner (11 participants out of 16). Age, apraxia of speech severity and initial anomia severity impacted therapy gains. Conclusions & Implications: Though more research is needed, results suggest Fr‐PCA benefits French individuals living with aphasia. Identifying individual factors influencing therapy gains could enable clinicians to improve therapy tailoring. WHAT THIS PAPER ADDS: What is already known on this subject: Phonological Component Analysis (PCA) improves naming of treated and untreated items in individuals living with aphasia. There is also evidence supporting long‐lasting benefits following PCA. However, PCA has never been studied in French, a language presenting with a different linguistic typology than English, and we know little as to which individual factors can influence PCA therapy benefits. What this paper adds to existing knowledge: Through group‐level analyses on both personalized sets and standardized tests, this study shows that PCA constitutes an effective therapy protocol for francophone individuals living with aphasia. The gains are measured on treated and untreated items and generalized to levels other than naming, such as communication effectiveness. Individual factors such as age, initial anomia severity and apraxia of speech severity influence therapy outcomes. What are the potential or actual clinical implications of this work?: There is now evidence supporting PCA in French, a language with strong morphological‐phonological interactions. Furthermore, when working with individuals living with aphasia and severe anomia or apraxia of speech, gains can still be made, but might be longer to attain. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Micro- and Macrostructural Language Features in Vertebrobasilar or Carotid System Stroke Without Diagnosis of Aphasia.
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Canlı, Burçak, Savaş, Merve, and Beğen, Senanur Kahraman
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DIAGNOSIS of aphasia , *ARTERIAL injuries , *CAROTID artery injuries , *LANGUAGE & languages , *READING , *COMPARATIVE grammar , *COMMUNICATIVE competence , *ANOMIA , *COMPUTER software , *DATA analysis , *KRUSKAL-Wallis Test , *NARRATIVES , *UNCERTAINTY , *DESCRIPTIVE statistics , *MANN Whitney U Test , *SOUND recordings , *ISCHEMIC stroke , *SPEECH evaluation , *MEAN length of utterance , *PUBLISHING , *STATISTICS , *JUDGMENT (Psychology) , *DATA analysis software , *EVALUATION , *WRITTEN communication , *EDUCATIONAL attainment , *DISEASE risk factors - Abstract
Purpose: This study aimed to investigate the macro- and microstructural features of language in patients with ischemic stroke without aphasia. Method: Participants were grouped according to arterial system damage and given the Aphasia Language Assessment Test (ADD) to detect aphasia. A narrative sample was obtained and analyzed for macrostructural and microstructural features of the language. The study sample consisted of 31 participants with ischemic stroke (15 vertebrobasilar system [VBS] involvement and 16 carotid system [CS] involvement) and 31 healthy participants, totaling 62 individuals. Results: The healthy control group scored higher than the stroke group on the microstructural feature type–token ratio and mean length of utterance in the narrative analysis and on the auditory comprehension, repetition, naming, grammar, speech act, and writing subtests in ADD. Effort behavior, errors, edits, repetitions, and pauses among microstructural features and uncertainty, filler expression, and anomia among macrostructural features were significantly higher in the vertebrobasilar and CS groups than in the healthy control group. The total ADD score and speech fluency and reading subtest scores were significantly higher in individuals with VBS damage than in individuals with CS lesions (p < .05). Conclusions: Language components may be impaired differently in patients with carotid and vertebrobasilar lesions. Speech and language disorders in individuals who have experienced cerebrovascular accidents should be evaluated in the subacute and chronic phases, and the therapeutic needs of patients with ischemic stroke should be determined, regardless of the presence of a clinical aphasia diagnosis. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Determinants of Multilevel Discourse Outcomes in Anomia Treatment for Aphasia.
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Cavanaugh, Robert, Dickey, Michael Walsh, Hula, William D., Fromm, Davida, Golovin, Jennifer, Wambaugh, Julie, Fergadiotis, Gerasimos, and Evans, William S.
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COMPARATIVE grammar , *ANOMIA , *PHONOLOGICAL awareness , *EXECUTIVE function , *APHASIA , *RETROSPECTIVE studies , *EVALUATION of medical care , *ATTENTION , *LINGUISTICS , *MOTIVATION (Psychology) , *MEMORY , *COMMUNICATION , *SEMANTICS , *DATA analysis software - Abstract
Purpose: Individuals with aphasia identify discourse-level communication (i.e., language in use) as a high priority for treatment. The central premise of most aphasia treatments is that restoring language at the phoneme, word, and/or sentence level will generalize to discourse. However, treatment-related changes in discourse-level communication are modest, are poorly understood, and vary greatly among individuals with aphasia. In response, this study consisted of a multilevel discourse analysis of archival, monologic discourse outcomes across two high-intensity Semantic Feature Analysis (SFA) clinical trials. Aim 1 evaluated changes in theoretically motivated discourse outcomes representing lexical-semantic processing, lexical diversity, grammatical complexity, and discourse informativeness. Aim 2 explored the potential moderating role of nonlanguage cognitive factors (semantic memory, divided attention, and executive function) on discourse outcomes. Method: This study was a retrospective analysis of archival monologic discourse outcomes after intensive SFA for n = 60 (Aim 1) and a subset n = 44 (Aim 2). Outcome measures included lexical-semantic processing (% semantic errors), lexical diversity (moving average type-token ratio), grammatical complexity (mean utterance length), and discourse informativeness (% correct information units). Bayesian generalized mixed-effects models were used to examine changes across four study time points: enrollment, entry, exit, and 1-month follow-up. Results: The present study found no evidence for meaningful or statistically reliable improvements in monologue discourse performance after SFA when measured using standard, general-topic discourse stimuli. There was weak and inconsistent evidence that nonlanguage cognitive factors may play a role in moderating treatment response. Conclusions: These findings indicate a clear need to pair theoretically informed treatments designed to facilitate generalization to discourse with intentional measurement paradigms designed to capture it. Furthermore, there is a clear need to examine how established treatments, restorative or compensatory, can better facilitate generalization to discourse-level communication. These priorities are critical for meaningfully improving everyday communication and reducing the profound communication and psychosocial consequences of aphasia. [ABSTRACT FROM AUTHOR]
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- 2024
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9. What Conversation Topics are Meaningful to People with Aphasia? A qualitative study.
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Devane, Niamh, Buxton, Shannon, Fox, Chelsie, Marshall, Jane, Staunton, Deirdre, Whiddett, Jennifer, Wilson, Stephanie, and Hilari, Katerina
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CONVERSATION , *QUALITATIVE research , *APHASIA , *FAMILIES , *CHRONIC diseases , *THEMATIC analysis , *FOOD , *EXPERIENCE , *PATIENTS' attitudes , *SPEECH therapy , *VIDEO recording , *FRIENDSHIP , *BEVERAGES - Abstract
Speech and language therapists apply word finding therapies for people with aphasia with good outcomes on treated words but limited evidence of generalisation to untreated words. As generalisation cannot be assumed, there is a need to select words for therapy that are meaningful to people with aphasia. This study sought the views of people with aphasia to inform the stimuli for a word finding in conversation treatment. To this end, the research question was: What conversation topics do people with aphasia find most meaningful to talk about? This qualitative study used focus groups to identify meaningful conversation topics across a sample of 12 people with chronic aphasia (two groups of six). Participants were recruited from three community aphasia groups. The focus groups were videoed and transcribed. The transcription was analysed using framework analysis. A consensus decision process was then used by researchers to identify the themes with high agreement. Twenty conversation topics were generated. Consensus was that eight topics were meaningful. The three topics rated most meaningful were 1) family and friends, 2) food and drink, and 3) living with aphasia. Two topics reached consensus as not meaningful. Ten topics did not reach consensus. The conversation topics, 'family and friends', 'food and drink' and 'living with aphasia' were most meaningful to this sample of people with aphasia. Using therapy stimuli from these conversation topics has the potential to create meaningful treatments. [ABSTRACT FROM AUTHOR]
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- 2024
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10. "I don't know who you are": anomia for people's names in Alzheimer's disease.
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Gomes, Vanessa, Simón, Teresa, and Lázaro, Miguel
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ALZHEIMER'S disease , *DISEASE nomenclature , *OLDER people - Abstract
It is well known that difficulty in the retrieval of people's names is an early symptom of Alzheimer's Disease Dementia (ADD), but there is a controversy about the nature of this deficit. In this study, we analyzed whether the nature of the difficulty in retrieving proper names in ADD reflects pre-semantic, semantic, or post-semantic difficulties. To do so, 85 older adults, 35 with ADD and 50 cognitively healthy (CH), completed a task with famous faces involving: recognition, naming, semantic questions, and naming with phonological cues. The ADD group scored lower than the CH group in all tasks. Both groups showed a greater capacity for recognition than naming, but this difference was more pronounced in the ADD group. Additionally, the ADD group showed significantly fewer semantic errors than the CH group. Overall results suggest that the difficulties people with ADD have in naming reflect a degradation at semantic level. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Una relectura de «Un país al margen de la ley» desde el aporte del institucionalismo
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Carolina Fernández Blanco
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carlos nino ,institucionalismo ,anomia ,desarrollo ,legislación ,Law in general. Comparative and uniform law. Jurisprudence ,K1-7720 ,Jurisprudence. Philosophy and theory of law ,K201-487 - Abstract
En 2022 se cumplieron 30 años de la publicación de «Un país al margen de la ley» de Carlos Nino, este artículo revisa ese trabajo del autor argentino a la luz de los enfoques institucionalistas del desarrollo que se instalaron como principal corriente de pensamiento desde la década de 1990 y que continúan teniendo una fuerte influencia. La revisión que se realiza comparte algunos puntos de partida de «Un país al margen de la ley» pero también ofrece una visión crítica del trabajo y de algunas ideas institucionalistas. La idea central del trabajo es que la descripción que realiza Nino sobre la anomia en Argentina (extensible en la mayoría de los casos al resto de América Latina) no es tanto un producto sociológico o de raigambre histórica como un problema «de la ley». Por lo tanto, las miradas para superar la anomia deberían orientarse a los modelos de discusión y producción legislativa. Finalmente, el artículo realiza una breve reseña de la situación de la Argentina de hoy, evaluando qué ha cambiado desde que Nino escribiera el libro del que se ocupa este trabajo.
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- 2024
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12. Virtual Reality Training for Aphasia Rehabilitation (Aphasia360)
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Fondazione Poliambulanza and Claudia Repetto, Associate Professor
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- 2024
13. Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation (GWI HDtDCS)
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John Hart, Jr., Professor
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- 2024
14. Predictors of self-reported word-finding difficulties in glioma patients – a longitudinal study.
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Ottarsdottir, Edda, Zamanzad Ghavidel, Fatemeh, Vesterli Tveiten, Øystein, Specht, Karsten, and Wehling, Eike
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SELF-evaluation , *RISK assessment , *PREOPERATIVE period , *GLIOMAS , *ANOMIA , *RESEARCH funding , *DESCRIPTIVE statistics , *SURGICAL complications , *PSYCHOLOGICAL stress , *POSTOPERATIVE period , *VOCABULARY , *REGRESSION analysis , *DISEASE risk factors - Abstract
Background: Word-finding difficulties are a common self-reported concern in glioma patients known to negatively affect social participation and life satisfaction. Discrepancies between self-reported difficulties and performance on objective tests have been reported, but studies are seldom conducted longitudinally. Aims: The aim of the present study was to examine the occurrence of self-reported word-finding difficulties before and during the first year after glioma surgery. In addition, we investigated whether self-reported word-finding difficulties were predicted by standardized language tests and psychological distress. Methods and procedures: Twenty-three patients with gliomas (grade 1–3) were assessed pre-surgery, at six and twelve months follow-up. Self-reported word-finding difficulties were addressed with the item I am able to find the right word(s) to say what I mean, from the Functional Assessment of Cancer Therapy – Brain (FACT-Br). Confrontation naming was tested with the Boston Naming Test (BNT), word production with a semantic fluency test and word knowledge with a vocabulary test. Self-reported measures of psychological distress were assessed with the Hospital Anxiety and Depression Scale (HADS). Ordinal regression models were used to examine predictors of self-reported word-finding difficulties. Outcomes and results: Word-finding difficulties were reported by 68% of the patients pre-surgery, increasing to 90% and 85% at the following assessments. Significant changes were observed in the magnitude of reported concerns between pre-surgery assessment and six months follow-up. Regression analyses demonstated that self-reported word-finding difficulties were predicted by psychological distress and vocabulary pre-surgery and vocabulary at six months follow-up, whereas confrontation naming and semantic fluency did not become significant in any of the assessments. Conclusion: Our results indicate that self-reported word-finding difficulties occurred in a high percentage of glioma patients throughout the first year of illness. Patients reported increased difficulties after surgery that were not predicted by confrontation naming or semantic fluency but by vocabulary performance. The results imply further that psychological distress is a factor that should be taken into account. Self-reported function is an important supplement to objective testing and can provide indications about mental health status and the patients' perspective on language related challenges in everyday life. [ABSTRACT FROM AUTHOR]
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- 2024
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15. Sin and Perfection in 1 John
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Kruse Colin G.
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sin ,perfection ,fellowship ,children of god ,anomia ,assurance ,eternal life ,Philosophy. Psychology. Religion - Abstract
Early in 1 John, the author portrays authentic Christian living as involving honest and ongoing acknowledgment of one’s sins, God’s forgiveness of the same, and the cleansing from all unrighteousness (1:8-9). However, later in the same letter, while seeking to distinguish his opponents from those who were the true children of God, he says: ‘No one who abides in him sins; no one who sins has either seen him or known him’ (3:6); and ‘those who have been born of God do not sin, because God’s seed abides in them; they cannot sin, because they have been born of God.’ (3:9). These latter statements stand in tension with his earlier statement which says that anyone claiming to be without sin is a liar. In one place he rejects sinless perfection, in the other he appears to assume it. In this article these apparently contradictory statements are examined and a possible resolution of the tension existing between them is suggested.
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- 2024
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16. The efficacy of confrontational naming treatments for aphasia: a meta-analysis.
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Yousefzade, Fahime, Memarian, Asefeh, Rahimi, Alireza, and Ghasisin, Leila
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APHASIC persons , *APHASIA , *HOMOGENEITY , *DATABASES - Abstract
BackgroundObjectiveMethodsResultsConclusionsPrevious systematic reviews and meta-analyses have only mentioned a few confrontational naming treatment methods. There is no recent literature on the effect of different treatment methods and on comparing their efficacy with each other.The purpose of this study was to: a) collect treatment methods for addressing confrontational naming deficits in patients with aphasia; b) examine the number of studies on treatment methods; c) evaluate the level of evidence for these treatment methods; d) determine the efficacy of the explored treatment methods; and e) compare various treatment methods.We searched Scopus, ISI Web of Sciences, PubMed, Cochrane Library, ProQuest, Clinical Key, Science Direct, and Springer electronic databases for articles published from January 2009 to March 2023. A meta-analysis was conducted using comprehensive meta-analysis (CMA2) software. A funnel plot was applied to examine the influence of outliers. Furthermore, Cochran’s Q test and the I-square (I2) index were utilized to assess the homogeneity of effect sizes in the included studies.Of the 1808 articles identified, 66 were included in the final synthesis (1496 participants). Among the studies reviewed, 62.69% were found to have high effect sizes, 19.40% had medium effect sizes, and 17.91% showed an effect size of less than 0.3, indicating low efficacy. The syntactic cueing method, errorless learning, and action observation methods had high effect sizes (E.S = 0.93, E.S = 0.89, E.S = 0.88, respectively). The personalized cueing method had low effect sizes (E.S = 0.22).This systematic review extracted and compared various treatment methods for naming deficits in individuals with aphasia. Evidence has shown that syntactic cueing, errorless learning, and action observation methods have the highest effect size and are, therefore, the most effective. Additionally, the SFA and gestural methods are effective interventions, considering the abundance of studies, high level of evidence, and substantial effect size. [ABSTRACT FROM AUTHOR]
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- 2024
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17. Common and proper nouns in mild Alzheimer’s disease.
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Zehtab, Sonia, Moayedfar, Saeideh, and Ghasisin, Leila
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NOUNS , *LAPTOP computers , *OLDER people , *SYMPTOMS , *COMPUTER software - Abstract
AbstractIntroductionMethodResultsConclusionDisturbance in naming accuracy and reaction time (RT) is one of the early symptoms of Alzheimer’s disease. Naming performance can be considered a diagnostic key in the early stages of Alzheimer’s disease (AD), which has remained diagnostically challenging. Although most of the studies in this field have been conducted on the naming accuracy of common nouns, others have shown that proper nouns are more sensitive for detecting the onset of AD. This study aims to compare the naming of common and proper nouns.Eighty pictures of common and proper nouns (40 items each) were presented to 18 healthy older adults and 18 people with mild Alzheimer’s disease using DMDX software on a laptop computer. The patients’ responses were transcribed into a pre-designed form, and their reaction times were captured by DMDX.Study results indicated a significant difference in the number of errors and RTs between proper and common nouns in patients with mild Alzheimer’s disease (
p -value=), implying that proper nouns may be more sensitive to mild AD. Moreover, patients with mild Alzheimer’s had more problems in common and proper nouns than healthy older adults.This study demonstrated that individuals with mild AD experienced greater difficulty recalling proper nouns, which were found to be more susceptible to the effects of AD. [ABSTRACT FROM AUTHOR]- Published
- 2024
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18. Visual Attention to Semantic and Orthographic Associations in Fluent Aphasia: Evidence from Eye-Tracking.
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DeMetropolis, Susan M. and Pittarello, Andrea
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READING , *TASK performance , *PROMPTS (Psychology) , *ANOMIA , *EYE movement measurements , *PHONOLOGICAL awareness , *APHASIA , *ATTENTION , *CASE-control method , *SEMANTICS , *VISUAL perception , *STROKE - Abstract
We examined the allocation of visual attention in an association task by both neurotypical participants (n = 11) and adults with fluent aphasia (n = 12). Participants were presented with a picture (e.g., a basket) followed by a semantically related association (i.e., "strawberry") and an orthographically related association (i.e., "b," the first letter of "basket"). An eye tracker recorded their eye movements for three areas of interest (AOI): the picture, the semantic associate, and the orthographic associate, over 1396 observations. Results showed that both neurotypical participants and participants with aphasia looked longer at the semantic associate than at the picture, and this difference was more pronounced for neurotypicals than for people with aphasia (PWA). Neurotypicals also looked longer than the PWA group at the orthographic associate than at the prior picture. Regarding eye fixation counts, both participant groups looked more frequently at the semantic associate than at either the picture or the orthographic associate. Notably, this pattern was more pronounced among neurotypical participants than PWA. Our findings emphasize the importance of semantic associations in fluent aphasia and suggest a potential rehabilitative approach in speech and language therapy. [ABSTRACT FROM AUTHOR]
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- 2024
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19. Dissociation of reading and naming in ventral occipitotemporal cortex.
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Woolnough, Oscar and Tandon, Nitin
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DIAGNOSTIC imaging , *BRAIN mapping - Abstract
Lesions in the language-dominant ventral occipitotemporal cortex (vOTC) can result in selective impairment of either reading or naming, resulting in alexia or anomia. Yet, functional imaging studies that show differential activation for naming and reading do not reveal activity exclusively tuned to one of these inputs. To resolve this dissonance in the functional architecture of the vOTC, we used focused stimulation to the vOTC in 49 adult patients during reading and naming, and generated a population-level, probabilistic map to evaluate if reading and naming are clearly dissociable within individuals. Language mapping (50 Hz, 2829 stimulations) was performed during passage reading (216 positive sites) and visual naming (304 positive sites). Within the vOTC, we isolated sites that selectively disrupted reading (24 sites in 11 patients) or naming (27 sites in 12 patients), and those that disrupted both processes (75 sites in 21 patients). The anteromedial vOTC had a higher probability of producing naming disruption, while posterolateral regions resulted in greater reading-specific disruption. Between them lay a multi-modal region where stimulation disrupted both reading and naming. This work provides a comprehensive view of vOTC organization—the existence of a heteromodal cortex critical to both reading and naming, along with a causally dissociable unimodal naming cortex, and a reading-specific visual word form area in the vOTC. Their distinct roles as associative regions may thus relate to their connectivity within the broader language network that is disrupted by stimulation, more than to highly selective tuning properties. Our work also implies that pre-surgical mapping of both reading and naming is essential for patients requiring vOTC resections, as these functions are not co-localized, and such mapping may prevent the occurrence of unexpected deficits. [ABSTRACT FROM AUTHOR]
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- 2024
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20. Identifying and Addressing Functional Communication Challenges in Patients With Behavioral Variant Frontotemporal Dementia.
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Meade, Gabriela, Machulda, Mary M., Clark, Heather M., Duffy, Joseph R., Botha, Hugo, Whitwell, Jennifer L., Josephs, Keith A., and Utianski, and Rene L.
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LANGUAGE & languages , *MOTOR ability , *ANOMIA , *RESEARCH funding , *FRONTOTEMPORAL dementia , *EXECUTIVE function , *EPISODIC memory , *QUESTIONNAIRES , *BEHAVIOR , *DESCRIPTIVE statistics , *COMMUNICATIVE disorders , *NEUROLOGICAL disorders , *APRAXIA , *NEUROPSYCHOLOGICAL tests , *CASE studies , *AGRAMMATISM , *BEHAVIOR therapy , *COGNITION - Abstract
Purpose: We describe the communication challenges of four patients with a neurodegenerative disorder consistent with behavioral variant frontotemporal dementia (bvFTD), characterized by early behavioral and personality changes. By describing their clinical profiles, we identify common barriers to functional communication in this population and provide recommendations for how speech-language pathologists (SLPs) might contribute to minimizing them. Method: Four patients with bvFTD were selected from a cohort of patients with progressive communication impairments. Three of them returned for at least one follow-up visit. Case histories are presented along with the results of comprehensive speech and language, neuropsychological, and neurological testing. Results: At the time of initial evaluation, patients were between the ages of 54 and 66 years and had been experiencing symptoms for 1.5-6 years. Consistent with their bvFTD diagnoses, all patients had prominent behavioral and personality changes that impacted communication. Patients 1 and 2 also had mild aphasia at enrollment, primarily characterized by anomia and loss of word meaning. Patients 3 and 4 both had apraxia of speech and moderate-to-severe aphasia at enrollment with prominent anomia and agrammatism. All four patients had impaired executive functioning and relative sparing of visuospatial skills; episodic memory was also impaired for Patients 2 and 4. Even though functional communication was progressively limited for all patients, none of them received regular support from an SLP. Conclusions: This case series adds to a scant, but growing, literature demonstrating that patients with bvFTD have communication impairments. SLPs are uniquely positioned to identify barriers to functional communication and to provide tailored strategy training to the patients and their care partners over the course of their disease. Systematic evaluation of the efficacy of treatment in this population would be valuable. [ABSTRACT FROM AUTHOR]
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- 2024
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21. A Novel Morphology-Based Naming Therapy for People with Aphasia.
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Truzman, Tammar, Biran, Michal, Soroker, Nachum, Levy, Tamar, and Bitan, Tali
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ANOMIA , *CLINICAL trials , *APHASIA , *TREATMENT effectiveness , *PRE-tests & post-tests , *STROKE patients , *SPEECH therapy - Abstract
Background: Previous studies have demonstrated that naming treatments can improve language abilities in people with aphasia (PWA). However, there is currently a lack of protocols for evidencebased naming treatment in Hebrew. Aims: This study aims to evaluate the efficacy of a novel morphology-based naming treatment for Hebrew-speaking PWA and to investigate subject-related factors influence responsiveness to the treatment. Method & Procedures: Twelve chronic stroke PWA and moderate to severe anomia participated in 20 treatment sessions focused on the root-structure morphology of Hebrew. Treatment stimuli incorporated morphologically complex words comprising root and template. Treatment effects were assessed at both subject level and group level. Outcomes & Results: The treatment showed promising results, with a significant increase in correct naming for both treated and untreated complex words. These gains were maintained for at least 10 weeks post-treatment. Most of the benefit was achieved during the first 10 treatment sessions. Additionally, the group demonstrated generalization effects to naming simple words. Pre-treatment performance in naming morphologically complex words predicted higher treatment gains during the follow-up session, irrespective of word type. Conclusions: These findings provide preliminary evidence supporting the efficacy of root-based naming treatment for Hebrew-speaking PWA. Future research should compare this treatment to an untreated control group and to other treatment methods in Hebrew speakers to further validate its benefits. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Anomia in left hemisphere stroke, multiple sclerosis and Parkinson's disease – a comparative study.
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Kristensson, Joana, Longoni, Francesca, Östberg, Per, Rödseth Smith, Signe, Åke, Sabina, and Saldert, Charlotta
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CEREBRAL hemispheres , *RISK assessment , *CROSS-sectional method , *SELF-evaluation , *ANOMIA , *MULTIPLE sclerosis , *QUALITATIVE research , *DATA analysis , *RESEARCH funding , *QUESTIONNAIRES , *PARKINSON'S disease , *QUANTITATIVE research , *SEVERITY of illness index , *DESCRIPTIVE statistics , *RESEARCH methodology , *STATISTICS , *INTRACLASS correlation , *STROKE , *COMPARATIVE studies , *PSYCHOLOGICAL tests , *DATA analysis software , *DISEASE risk factors , *DISEASE complications - Abstract
To explore quantitative and qualitative features of anomia in participants with left-hemisphere stroke, Parkinson's disease, or multiple sclerosis. This descriptive cross-sectional study compares signs of anomia within and across participants (n = 87), divided into four groups; moderate to severe anomia after stroke (MSAS, n = 19), mild anomia after stroke (MAS, n = 22), PD (n = 19) and MS (n = 27). Aspects analysed include naming accuracy and speed, the nature of incorrect responses, semantic and phonemic verbal fluency, information content in re-telling, and the relationship between test results and self-reports on word-finding difficulties and communicative participation. All groups had impaired verbal fluency, prolonged response times and reduced information content in re-telling. The MSAS group had significantly more signs of anomia than the other groups. Results from the other groups overlapped on a MAS—PD—MS continuum. Both semantically and phonologically incorrect responses were common in the stroke groups, while semantically incorrect ones predominated in the PD and MS groups. All four groups reported a similar negative impact on self-perceived communicative participation. Correlations between self-reports and test results were inconsistent. Anomia features have quantitative and qualitative similarities and differences across neurological conditions. People with moderate or severe anomia after stroke not only exhibit more severe symptoms of word-finding difficulties but also manifest a wide variety of such symptoms, compared to people with Parkinson's disease or multiple sclerosis. The present findings underscore the need to ask patients about their self-perceived word-finding difficulties. Regardless of the degree of difficulties or the underlying condition, self-perceived word-finding difficulties can have a negative impact on communicative participation and should therefore be appropriately addressed. An assessment comprising aspects such as verbal fluency, connected-speech tasks and the measurement of response times in naming tasks may serve to affirm the self-reported word-finding difficulties. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Cultura e anomia no compartilhamento de dados: uma perspectiva a partir dos pesquisadores
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Elizabete Cristina de Souza de Aguiar Monteiro and Ricardo César Gonçalves Sant’Ana
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Anomia ,Compartilhamento de dados ,Cultura ,Gestão de dados ,Museums. Collectors and collecting ,AM1-501 ,Bibliography. Library science. Information resources - Abstract
Resumo A retenção ou publicação de dados pode diversificar conforme a cultura, os valores predominantes em determinada área do conhecimento ou as práticas adotadas por pesquisadores individuais. A anomia pode ocorrer quando há um desequilíbrio entre as metas institucionais e os valores culturais, com maior relevância dos valores culturais coletivos ou individuais. Dessa forma, pesquisadores podem não concordar com as metas institucionais e praticar condutas desviantes. O objetivo deste artigo foi apontar indícios da influência cultural sobre o estado de anomia em pesquisadores no processo de gestão e compartilhamento dos dados de sua pesquisa. Foi utilizada a pesquisa documental e exploratória e o método de análise de conteúdo com aplicação de framework que considera as dimensões institucional e individual. Os resultados apontaram indícios de que os pesquisadores têm pouca clareza sobre as metas institucionais para a gestão e o compartilhamento de dados. Conclui-se que a possível anomia no contexto dos pesquisadores está associada com desconhecimento ou dubiedade sobre as normas institucionais, sociais e morais, desequilíbrio entre as metas e os caminhos para atingi-las, descumprimento das orientações institucionais e pouca habilidade para a gestão de dados.
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- 2024
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24. Dominant, Lesional Temporal Pole Epilepsy
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Herlopian, Aline, Herlopian, Aline, editor, Spencer, Dennis Dee, editor, Hirsch, Lawrence J., editor, and King-Stephens, David, editor
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- 2024
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25. Focusing on the locus of the breakdown for treatment of anomia: a pilot study.
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Shekari, Ehsan, Mehrpour, Masoud, Joghataei, Mohammad Taghi, Modarres Zadeh, Amin, Valinejad, Vahid, Adineh, Hossain Ali, Seyfi, Milad, and Goudarzi, Sepideh
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ANOMIA , *SPEECH , *TASK performance , *DATA analysis , *T-test (Statistics) , *PHONOLOGICAL awareness , *PILOT projects , *CLINICAL trials , *APHASIA , *TREATMENT effectiveness , *DESCRIPTIVE statistics , *MANN Whitney U Test , *PRE-tests & post-tests , *STATISTICS , *SEMANTICS , *PHONETICS , *STROKE patients , *DATA analysis software , *SPEECH therapy , *AGRAMMATISM - Abstract
The primary goal of this study was to evaluate the treatment effects of semantic feature analysis (SFA) and phonological components analysis (PCA) on word retrieval processing in persons with aphasia (PWAs). After identifying the locus of the breakdown in lexical retrieval processing, 15 monolingual native Persian speakers with aphasia were divided into two groups. After three naming trials, participants with dominant semantic deficits received SFA, and participants with primary phonological deficits were provided with PCA three times a week for eight weeks. Both approaches improved participants' naming and performance on language tests, including spontaneous speech, repetition, comprehension, and semantic processing. However, the correct naming of treated and untreated items was higher in mild-to-moderate participants, with mostly circumlocution and semantic paraphasias in the SFA group. The same holds for mild-to-moderate participants with mostly phonemic paraphasia who received PCA therapy. Moreover, the results showed that participants' baseline naming performance and semantic abilities could be associated with the treatment outcomes. Although limited by a lack of a control group, this study provided evidence supporting the possible benefits of focusing on the locus of the breakdown for treating anomia through SFA and PCA approaches, specifically in participants with mild to moderate aphasia. However, for those with severe aphasia, the treatment choice may not be as straightforward because several variables are likely to contribute to this population's word-finding difficulties. Replication with larger, well-stratified samples, use of a within-subjects alternating treatment design and consideration of treatments' long-term effects are required to better ascertain the effects of focusing on the locus of breakdown for treatment of anomia. [ABSTRACT FROM AUTHOR]
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- 2024
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26. Environmental anomie and the disruption of physical norms during disaster.
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Brown, Adrienne R
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ANOMY , *DISASTERS , *SOCIAL norms , *LANDSCAPE changes , *SEMI-structured interviews , *WILDFIRES - Abstract
Large-scale disasters cause a wide variety of disruptions across impacted communities. Existing research has broadly addressed the ways in which both social norms and physical features constrain and dictate everyday life. During disasters, vast disruptions occur to both social and physical norms, which can have negative impacts on people's sensemaking processes. This study uses transcripts from 24 semi-structured interviews conducted with people from Paradise several months after they survived the Camp Fire – at the time, California's most destructive wildfire. Drawing on Durkheim's classical theory of anomie along with extensive work done by environmental sociologists about the importance of place, I introduce the concept of environmental anomie. This recognizes the ways in which sudden changes to the physical landscape can upend the established order and can undermine people's ability to comprehend, relate to, and function within their environment. Expectations from the physical environment are a taken-for-granted authority that guide and constrain the routines of daily living and enable people to locate themselves spatially and temporally. The Camp Fire challenged this authority in a way that mirrors Durkheim's socially conceived idea of normlessness. [ABSTRACT FROM AUTHOR]
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- 2024
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27. Response Latencies During Confrontation Picture Naming in Aphasia: Are Proxy Measurements Sufficient?
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Mazumdar, Barnali, De la Mora, Nora, Roberts, Teresa, Swiderski, Alexander, Kapantzoglou, Maria, and Fergadiotis, Gerasimos
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PREDICTIVE tests , *ANOMIA , *SOUND spectrography , *PREDICTION models , *RESEARCH funding , *COMPUTERS , *DATA analysis , *PHONOLOGICAL awareness , *APHASIA , *DESCRIPTIVE statistics , *PROFESSIONS , *SPEECH evaluation , *MEDICAL records , *ACQUISITION of data , *INTRACLASS correlation , *REACTION time , *DATA analysis software , *HUMAN voice , *INTER-observer reliability , *REGRESSION analysis - Abstract
Purpose: Anomia, or word-finding difficulty, is a prevalent and persistent feature of aphasia, a neurogenic language disorder affecting millions of people in the United States. Anomia assessments are essential for measuring performance and monitoring outcomes in clinical settings. This study aims to evaluate the reliability of response time (RT) annotation based on spectrograms and assess the predictive utility of proxy RTs collected during computerized naming tests. Method: Archival data from 10 people with aphasia were used. Trained research assistants phonemically transcribed participants’ responses, and RTs were generated from the onset of picture stimulus to the initial phoneme of the first complete attempt. RTs were measured in two ways: hand-generated RTs (from spectrograms) and proxy RTs (automatically extracted online). Interrater agreement was evaluated based on interclass correlation coefficients and generalizability theory tools including variance partitioning and the ϕ-coefficient. The predictive utility of proxy RTs was evaluated within a linear mixed-effects framework. Results: RT annotation reliability showed near-perfect agreement across research assistants (ϕ-coefficient = .93), and the variance accounted for by raters was negligible. Furthermore, proxy RTs significantly and strongly predicted handannotated RTs (R² = ~0.82), suggesting their utility as an alternative measure. Conclusions: The study confirms the reliability of RT annotation and demonstrates the predictive utility of proxy RTs in estimating RTs during computerized naming tests. Incorporating proxy RTs can enhance clinical assessments, providing additional information for cognitive measurement. Further research with larger samples and exploring the impact of using proxy RTs in different psychometric models could optimize clinical protocols and improve communication interventions for individuals with aphasia. [ABSTRACT FROM AUTHOR]
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- 2024
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28. A Meta-Analysis of Anomia Treatment in Bilingual Aphasia: Within- and Cross-Language Generalization and Predictors of the Treatment Outcomes.
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Leea, Seongsil and Faroqi-Shaha, Yasmeen
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EFFECT sizes (Statistics) , *ANOMIA , *RESEARCH funding , *MULTIPLE regression analysis , *NEUROPLASTICITY , *CINAHL database , *PHONOLOGICAL awareness , *APHASIA , *TREATMENT effectiveness , *META-analysis , *DESCRIPTIVE statistics , *MANN Whitney U Test , *MULTILINGUALISM , *SYSTEMATIC reviews , *MEDLINE , *ONLINE information services , *DATA analysis software , *SPEECH therapy , *ERIC (Information retrieval system) , *PSYCHOLOGY information storage & retrieval systems , *EVALUATION - Abstract
Purpose: The present meta-analysis investigated the efficacy of anomia treatment in bilingual and multilingual persons with aphasia (BPWAs) by assessing the magnitudes of six anomia treatment outcomes. Three of the treatment outcomes pertained to the “trained language”: improvement of trained words (treatment effect [TE]), within-language generalization of semantically related untrained words (WLG-Related), and within-language generalization of unrelated words (WLG-Unrelated). Three treatment outcomes were for the “untrained language”: improvement of translations of the trained words (crosslanguage generalization of trained words [CLG-Tx]), cross-language generalization of semantically related untrained words (CLG-Related), and crosslanguage generalization of unrelated untrained words (CLG-Unrelated). This study also examined participant- and treatment-related predictors of these treatment outcomes. Method: This study is registered in the International Prospective Register of Systematic Reviews (PROSPERO) under the number CRD42023418147. Nine electronic databases were searched to identify word retrieval treatment studies of poststroke BPWAs of at least 6 months postonset. Pre- and posttreatment single-word naming scores were extracted for each eligible participant and used to calculate effect sizes (within-case Cohen’s d) of the six treatment outcomes. Random-effects meta-analyses were conducted to assess weighted mean effect sizes of the treatment outcomes across studies. Multiple linear regression analyses were used to examine the effects of participant-related variables (pretreatment single-word naming and comprehension representing poststroke lexical processing abilities) and treatment-related variables (type, language, and duration). The methodological quality of eligible studies and the risk of bias in this meta-analysis were assessed. Results: A total of 17 published studies with 39 BPWAs were included in the meta-analysis. The methodological quality of the included studies ranged from fair (n = 4) to good (n = 13). Anomia treatment produced a medium effect size for TE (M = 8.36) and marginally small effect sizes for WLG-Related (M = 1.63), WLG-Unrelated (M = 0.68), and CLG-Tx (M = 1.56). Effect sizes were nonsignificant for CLG-Related and CLG-Unrelated. TE was significantly larger than the other five types of treatment outcomes. TE and WLG-Related effect sizes were larger for BPWAs with milder comprehension or naming impairments and for treatments of longer duration. WLG-Unrelated was larger when BPWAs received phonological treatment than semantic and mixed treatments. The overall risk of bias in the meta-analysis was low with a potential risk of bias present in the study identification process. Conclusions: Current anomia treatment practices for bilingual speakers are efficacious in improving trained items but produce marginally small within-language generalization and cross-language generalization to translations of the trained items. These results highlight the need to provide treatment in each language of BPWAs and/or investigate other approaches to promote cross-language generalization. Furthermore, anomia treatment outcomes are influenced by BPWAs’ poststroke single-word naming and comprehension abilities as well as treatment duration and the provision of phonological treatment [ABSTRACT FROM AUTHOR]
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- 2024
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29. Salteadores y bandidos en tiempos de la anarquía militar. Anomia política, caos económico y auge criminal en el sur peruano a inicios de la República (1825-1845).
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Belan, César
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CRIMINAL procedure ,SUPERIOR courts ,ROBBERY ,ANARCHISM ,FINANCIAL crises - Abstract
Copyright of HiSTOReLo: Revista de Historia Regional y Local is the property of Universidad Nacional de Colombia, Centro Editorial Facultad de Ciencias Humanas y Economicas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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30. Coexisting with anomie: Experiences of persons living with early‐stage dementia: A grounded theory study.
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Kung, Pen‐Chen, Huang, Huei‐Ling, Hsu, Wen‐Chuin, Huang, Hsiu‐Li, Chang, Hong‐Jer, and Shyu, Yea‐Ing L.
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ANOMIA , *ALZHEIMER'S disease , *MENTAL health , *RESEARCH funding , *INTERVIEWING , *SOCIAL alienation , *PSYCHOLOGICAL adaptation , *DESCRIPTIVE statistics , *PSYCHOLOGICAL safety , *FAMILY relations , *EXPERIENCE , *EXPERIMENTAL design , *LONGITUDINAL method , *BURDEN of care , *CONCEPTUAL structures , *RESEARCH methodology , *COGNITION disorders , *QUALITY of life , *DEMENTIA , *GROUNDED theory , *PSYCHIATRIC nursing , *INTERPERSONAL relations , *SOCIAL support , *DEMENTIA patients , *PATIENTS' attitudes , *AVOIDANCE (Psychology) , *WELL-being - Abstract
Individuals in the early stages of dementia often endure elevated levels of stress and anxiety, which can hinder their ability to adapt to the progression of dementia. To mitigate the negative impacts of dementia more effectively, it is necessary to explore the trajectory of the adaptation process of persons living with dementia. This study aimed to construct a theoretical framework for the adaptation process of individuals in the early stages of dementia. Participants were dyads of persons diagnosed with mild dementia or mild cognitive impairment (≥ 60 years of age) and their primary family caregivers. This longitudinal study used a grounded theory approach to explore the adaptation trajectory changes in persons with mild dementia over a 3‐year period. Data were collected from dyads with face‐to‐face interviews. Analysis of the interview data revealed the core category was 'Coexisting with anomie: Progressive disappointment and striving', which was comprised of three categories: awareness of alienation, unsettled feelings, and restorative avoidance coping. Categories changed depending on levels of cognition and constituted progressive and cyclical dynamic processes. Four contextual factors positively or negatively influenced adaptation: level of insight about dementia, personal traits, caregiving style of the caregiver, and level of social interactions. These findings provide a new perspective about the mental health of persons in early‐stage dementia. Understanding coexisting with anomie and related influencing factors could facilitate the development of support interventions by mental health nursing staff, which could improve emotional safety, promote psychological well‐being, and increase quality of life for persons living with dementia. [ABSTRACT FROM AUTHOR]
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- 2024
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31. Early within therapy naming probes as a clinically-feasible predictor of anomia treatment response.
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Dignam, Jade, Rodriguez, Amy D., O'Brien, Kate, Burfein, Penni, and Copland, David A.
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SPEECH apraxia , *RESPONSE to intervention (Education) , *APHASIA , *TREATMENT effectiveness , *REGRESSION analysis - Abstract
This study investigated the relationship between early within-therapy probe naming performance and anomia therapy outcomes in individuals with aphasia. Thirty-four adults with chronic, post-stroke aphasia participated in the Aphasia Language Impairment and Functioning Therapy (Aphasia LIFT) programme, comprised of 48 h of comprehensive aphasia therapy. Sets of 30 treated and 30 untreated items identified at baseline were probed during impairment therapy which targeted word retrieval using a combined semantic feature analysis and phonological component analysis approach. Multiple regression models were computed to determine the relationship between baseline language and demographic variables, early within-therapy probe naming performance (measured after 3 h of impairment therapy) and anomia treatment outcomes. Early within-therapy probe naming performance emerged as the strongest predictor of anomia therapy gains at post-therapy and at 1-month follow-up. These findings have important clinical implications, as they suggest that an individual's performance after a brief period of anomia therapy may predict response to intervention. As such, early within-therapy probe naming may provide a quick and accessible tool for clinicians to identify potential response to anomia treatment. [ABSTRACT FROM AUTHOR]
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- 2024
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32. Determinants of Healthcare Expenditures among People with Aphasia: Importance of Race, Sex, Residence, and Aphasia Type.
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Jacobs, Molly, Evans, Elizabeth, and Ellis, Charles
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MEDICAL care costs , *RACE , *REGRESSION analysis , *APHASIA , *SEX distribution , *COMPARATIVE studies , *COST analysis , *QUESTIONNAIRES , *PSYCHOLINGUISTICS , *ANOMIA , *AGRAMMATISM , *RESIDENTIAL patterns , *STATISTICAL correlation , *CONDUCTION aphasia - Abstract
Roughly 30% of stroke survivors suffer from aphasia—a communication disorder that affects the ability to communicate effectively—but little is known about their healthcare expenditure or how it varies between aphasia subtypes. This study evaluates the relative differential in healthcare expenditure of anomic, Broca's, Wernicke's and Conduction aphasia and assesses expenditure between demographic cohorts Individual level data from the 2010 Moss Aphasia Psycholinguistic Project Database was matched with the 2010 Medical Expenditure Panel Survey using a propensity score algorithm based on functional, health, and demographic characteristics. Multilevel, generalized, nonlinear regression models were applied to the resulting data set to assess the correlation between annual healthcare expenditure, time post onset (tpo), sex, race, family size, marital status, income, education, aphasia type, and region of residence. Results were used to predict expenditure by aphasia subtype, race, and sex. Multiple distributional specifications tested the sensitivity and ensured the robustness of estimates. Regression results indicate that individuals with Broca's aphasia had statistically higher healthcare expenditures paying an average of $10,896.45 annually when compared to anomic ($7,927.60), Wernicke's ($7,096.22), and Conduction ($9,447.19) aphasias. Additionally, healthcare expenditure increased with each year of age (β=0.004, SE=0.005), but decreased with each year after stroke (β=-0.002, SE=0.001). Females (β=0.358, SE=0.131) and Blacks (β=0.103, SE=0.200) paid significantly more annually compared to males and Whites, respectively. Neither region of residence, income, nor level of education were significantly correlated with healthcare expenditure. This study showed that, while individuals with Broca's aphasia had higher average healthcare expenditure than other subtypes, the differential was not statistically significant. Sex and race cohorts did, however, show statistically significant differences in healthcare expenditures. While causality is outside the scope of this analysis, additional work is needed to determine the best strategy to mitigate these disparities. [ABSTRACT FROM AUTHOR]
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- 2024
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33. Discourse Task Type--Specific Linguistic Characteristics in Anomic Aphasia and Healthy Controls: Evidence From Mandarin--Chinese AphasiaBank.
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Bao-Mei Deng, Jing Gao, Li-Si Liang, Jia-Xin Zhao, Feng Lin, Ming-Yu Yin, Hai-Qing Zheng, and Xi-Quan Hu
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REPEATED measures design , *PEARSON correlation (Statistics) , *ANOMIA , *TASK performance , *T-test (Statistics) , *DATA analysis , *RESEARCH funding , *PHONOLOGICAL awareness , *APHASIA , *DESCRIPTIVE statistics , *MANN Whitney U Test , *CHI-squared test , *LINGUISTICS , *HYPOTHESIS , *STATISTICS , *DATA analysis software - Abstract
Purpose: This study was designed to examine the hypothesis that discourse task types influence language performance in Mandarin Chinese--speaking people and to reveal the discourse task-specific linguistic properties of persons with anomic aphasia compared to neurotypical controls. Method: Language samples from persons with aphasia (n = 31) and age- and education-matched controls (n = 31) across four discourse tasks (sequential-picture description, single-picture description, story narrative, and procedural discourse) were collected from Mandarin AphasiaBank. Task-specific distributions of parts of speech were analyzed using mosaic plots. The main effects of tasks in each group and the between-group differences within each task for several typical linguistic variables were evaluated, including the mean length of utterance, tokens, moving-average type-token ratio, words per minute, propositional density, noun--verb ratio, noun percentage, and verb percentage. Results: The results revealed an impact of discourse tasks on most language variables in both groups. In the healthy controls, story narratives yielded the highest total words and lowest verb percentage. In the aphasia group, procedural discourse elicited the fewest total words and densest expressions, whereas their single-picture descriptions had the highest noun--verb ratio. For all tasks, the aphasia group performed worse than the control group in the mean length of utterance, tokens, moving-average type-token ratio, and words per minute. For noun--verb ratio, noun percentage, and verb percentage, only one task (i.e., single-picture description) showed significant between-group differences. Conclusion: The selection of discourse tasks should be addressed in assessments and interventions for Mandarin Chinese--speaking individuals with aphasia to obtain more accurate and feasible outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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34. Correct Information Unit Analysis in Different Discourse Tasks Among Persons With Anomic Aphasia Based on Mandarin AphasiaBank.
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Bao-Mei Deng, Li-Si Liang, Jia-Xin Zhao, Hai-Qing Zheng, and Xi-Quan Hu
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SPEECH evaluation , *DISABILITIES , *COMMUNICATIVE competence , *PEARSON correlation (Statistics) , *ANOMIA , *TASK performance , *T-test (Statistics) , *DATA analysis , *RESEARCH funding , *PHONOLOGICAL awareness , *APHASIA , *MANN Whitney U Test , *CHI-squared test , *DESCRIPTIVE statistics , *DISCOURSE analysis , *COMMUNICATIVE disorders , *STATISTICS , *DATA analysis software , *PEOPLE with disabilities , *INTER-observer reliability ,RESEARCH evaluation - Abstract
Purpose: This study aimed to explore how well persons with anomic aphasia communicate information during discourse regarding quantity, quality, and efficiency compared to neurotypical controls, to investigate the influence of discourse tasks on informativeness and efficiency and to examine impact factors like aphasia severity and cognitive ability. Method: Language samples of four discourse tasks from 31 persons with anomic aphasia and 31 neurotypical controls were collected from Mandarin AphasiaBank. Correct information unit (CIU) analysis measures including the total number of CIUs, percentage of CIUs, CIUs per minute, and words per minute were calculated. Group differences and the effects of discourse tasks on informativeness and efficiency were investigated. Correlations of CIU analysis measures with aphasia severity and cognitive ability were examined. Results: Persons with anomic aphasia showed lower efficiency in conveying information than controls. They underperformed controls on all CIU analysis measures when executing story narrative tasks. Discourse tasks influenced the informativeness and efficiency of both groups. Neurotypical controls delivered the greatest quantity of information most efficiently when narrating stories. Persons with anomic aphasia exhibited reduced quantity of information during procedural discourse and displayed superior information quality in sequential-picture descriptions. Discourse information may be impacted by aphasia severity and cognitive ability, with varying effects depending on the task. Conclusions: Persons with anomic aphasia are inefficient in communicating discourse messages and perform poorly on all measures in story narratives. When measuring discourse information, the effects of discourse tasks and factors like aphasia severity and cognitive ability should be considered. [ABSTRACT FROM AUTHOR]
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- 2024
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35. Perceptions of communication recovery following traumatic brain injury: A qualitative investigation across 2 years.
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Elbourn, Elise, Brassel, Sophie, Steel, Joanne, and Togher, Leanne
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REHABILITATION for brain injury patients , *ATTITUDES toward illness , *QUALITATIVE research , *ANOMIA , *DYSARTHRIA , *RESEARCH funding , *INTERVIEWING , *FATIGUE (Physiology) , *COMMUNICATIVE disorders , *SOUND recordings , *THEMATIC analysis , *CONVALESCENCE , *SOCIAL networks , *BRAIN injuries , *SOCIAL support , *PATIENTS' attitudes , *VIDEO recording , *MEMORY disorders , *SELF-perception , *HEALTH care teams , *HOPE , *DISEASE risk factors , *DISEASE complications - Abstract
BACKGROUND: Exploring the perceptions of individuals with traumatic brain injury (TBI) towards their brain injury recovery across the continuum of care may offer insights to support engagement with rehabilitation services. Illness narratives are a potentially valuable avenue for examining perceptions of recovery that may influence engagement. AIMS: The aim of this study is to explore the perspective of individuals with severe TBI towards their communication, brain injury and recovery experiences at 6 months, 1 year and 2 years post‐injury. METHODS & PROCEDURES: Discourse samples were obtained from 12 participants with severe TBI at 6 months, 1 year and 2 years following injury. A standardised protocol was used to elicit responses relating to perceptions of communication, the brain injury narrative, and perceptions of recovery facilitators. A thematic analysis of the discourse samples was completed. OUTCOMES & RESULTS: Three overarching themes were identified: experiences of communication recovery are diverse (Theme 1), varied experiences of recovery and rehabilitation (Theme 2), and continuous and lifelong journey of recovery (Theme 3). Primary communication concerns included presence of anomia, dysarthria, conversational topic difficulties, impacts of fatigue and memory difficulties. Illness narratives revealed the importance of re‐establishing a sense of self and the perceived importance of a strong social network post‐injury. CONCLUSIONS & IMPLICATIONS: The varied nature of communication challenges and recovery after TBI highlights the need for holistic, multidisciplinary support as well as inclusion of family and friends in the recovery process. Social communication intervention is a perceived priority area for individuals with TBI. Illness narratives may also play a valuable role in therapy and help to shape post‐injury identity. Managing the impacts of fatigue on communication and encouraging individuals to take ownership over their recovery and treatment may also help to improve patient outcomes. Supporting individuals to construct positive brain injury narratives that reaffirm a sense of self and include perspectives of family and friends may offer a potential future avenue for rehabilitation. Tailored but flexible, team‐based service delivery models for individuals with TBI that span from acute to long‐term care are warranted. What this study adds?: What is already known on this subject: Communication recovery from traumatic brain injury (TBI) is complex and multifaceted. The perceptions of individuals with TBI toward their communication recovery is largely unknown. To establish rehabilitation services that meet the needs of these individuals, we need to understand how they experience communication recovery. What this paper adds to existing knowledge: Social communication interventions were perceived as a priority for intervention by individuals with TBI. Fatigue was identified as perceived barrier to communication recovery. Taking ownership over one's recovery process was revealed as a facilitator of recovery. Illness narratives were found to strengthen post‐injury identity over time. What are the potential or actual clinical implications of this work?: Speech pathologists should prioritise social communication interventions and fatigue management for communication. Facilitating ownership of the recovery process and offering long‐term supports are key aspects of treatment. Supporting positive illness narratives as part of treatment may facilitate post‐injury identity construction. [ABSTRACT FROM AUTHOR]
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- 2024
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36. Recuperación de nombres propios en personas con demencia tipo Alzheimer: Un estudio piloto.
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Gomes, Vanessa, Simón, Teresa, and Lázaro, Miguel
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OLDER people ,ALZHEIMER'S disease ,CELEBRITIES ,CHILDREN with dyslexia ,COGNITION - Abstract
Copyright of Revista Signos is the property of Pontificia Universidad Catolica de Valparaiso and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
37. Mechanisms Underlying Spoken Language Production
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Jenny Crinion, Professor Jennifer Crinion
- Published
- 2023
38. The Rapid Naming Test: Development and initial validation in typically aging adults.
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Stiver, Jordan, Staffaroni, Adam, You, Michelle, Casaletto, Kaitlin, Erlhoff, Sabrina, Possin, Katherine, Lukic, Sladjana, La Joie, Renaud, Zimmerman, Molly, Gorno-Tempini, Maria, Kramer, Joel, Rabinovici, Gil, and Walters, Samantha
- Subjects
Confrontation naming ,anomia ,lexical retrieval ,tip-of-the-tongue ,word finding ,Aged ,Aging ,Amyloid beta-Peptides ,Biomarkers ,Humans ,Language ,Neuropsychological Tests ,Reproducibility of Results - Abstract
ObjectiveProgressive word-finding difficulty is a primary cognitive complaint among healthy older adults and a symptom of pathological aging. Classic measures of visual confrontation naming, however, show ceiling effects among healthy older adults. To address the need for a naming test that is sensitive to subtle, age-related word-finding decline, we developed the Rapid Naming Test (RNT), a computerized, one-minute, speeded visual naming test.MethodFunctionally intact older (n = 145) and younger (n = 69) adults completed the RNT. Subsets of older adults also completed neuropsychological tests, a self-report scale of functional decline, amyloid-β PET imaging, and repeat RNT administration to determine test-retest reliability.ResultsRNT scores were normally distributed and exhibited good test-retest reliability. Younger adults performed better than older adults. Within older adults, lower scores were associated with older age. Higher scores correlated with measures of language, processing speed, and episodic learning and memory. Scores were not correlated with visuospatial or working memory tests. Worse performance was related to subjective language decline, even after controlling for a classic naming test and speed. The RNT was also negatively associated with amyloid-β burden.ConclusionsThe RNT appears to be a reliable test that is sensitive to subtle, age-related word-finding decline. Convergent and divergent validity are supported by its specific associations with measures relying on visual naming processes. Ecological validity is supported by its relationship with subjective real-world language difficulties. Lastly, worse performance was related to amyloid-β deposition, an Alzheimers disease biomarker. This study represents a key step toward validating a novel, sensitive naming test in typically aging adults.
- Published
- 2022
39. El ideal de la villa como comunidad y su realidad de estigmatización: la experiencia de la Villa Don Bosco en Limpio
- Author
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Salustiana Caballero
- Subjects
comunidad ,villa ,estigma ,ciudad ,anomia ,Social Sciences - Abstract
Este trabajo aborda el desarrollo de un asentamiento urbano planificado, desde la visión y experiencia de sus promotores y sus habitantes iníciales. Se trata de un estudio exploratorio inédito, denominado “El ideal de la villa como comunidad y su realidad de estigmatización: La experiencia de la Villa Don Bosco en Limpio”. La misma fue realizada entre los años 2011 y 2012. Sin embargo, posee vigencia considerando que existen escasos trabajos que indagan los efectos de urbanizaciones planificadas en el Paraguay y puede contribuir a las políticas públicas que promueven soluciones habitacionales en la actualidad, más ante el acelerado proceso de urbanización que afronta el país. La recolección de datos fue realizada desde una metodología cualitativa a través de 15 entrevistas semiestructuradas a informantes claves, de ellas a 8 mujeres y 7 varones, entre planificadores y primeros habitantes. A partir del análisis se constató que el proceso de esta urbanización mantuvo dos ideales, por un lado, los planificadores deseaban formar una Comunidad tradicional en términos sociológicos, mientras que, por el otro, los primeros habitantes pretendían la propiedad y vivienda propia al estilo de una sociedad/ciudad. Así también, añoraban salir del bañado para abandonar el estigma de marginales, sin embargo, con la denominación de Villa, pasaron a construir una nueva identidad social, la de ser villeros, villa gua, y con ella una renovación de sus condiciones de estigmatización.
- Published
- 2023
- Full Text
- View/download PDF
40. Speeded Anomia Treatment in Chronic Post-stroke Aphasia
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Cambridge University Hospitals NHS Foundation Trust and Matthew A. Lambon Ralph, Professor
- Published
- 2023
41. The effects of adding attention training to naming treatment for individuals with aphasia.
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Modarres Zadeh, Amin, Mehri, Azar, Murray, Laura L., Nejati, Vahid, and Khatoonabadi, Ahmad Reza
- Abstract
AbstractAimMaterials and methodsResultsConclusionGiven the ever-increasing evidence for the co-occurrence of attention impairments and language disorders in chronic aphasia, this study aimed to compare the effects of two naming treatment programs, one with and one without attention training components, on the naming performance of participants with aphasia.This was a single-subject crossover study in which six people with chronic aphasia and different degrees of naming and attention impairments participated. Two treatment programs were implemented for each participant, with the sequence of the treatments with crossover design. Each program consisted of 12 treatment sessions plus pre- and post-treatment assessment sessions (15 weeks for each participant). The visual analysis and WEighted STatistics methods were employed for data analysis.Based on visual analysis, both treatments improved in comparison to the baseline phase. Statistical analysis revealed that the number of participants with significant naming improvement following combined program (5 participants) was larger than the number of participants showing improvement following completion of the single, program.Although integrating attention training into a conventional treatment for anomia can increase the effect of treatment on naming ability, more studies are required to clarify the role of attention in remediating naming impairments in aphasia. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
42. Baseline Conceptual-Semantic Impairment Predicts Longitudinal Treatment Effects for Anomia in Primary Progressive Aphasia and Alzheimer's Disease.
- Author
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Meyer, Aaron M., Snider, Sarah F., Tippett, Donna C., Saloma, Ryan, Turkeltaub, Peter E., Hillis, Argye E., and Friedman, Rhonda B.
- Subjects
- *
ALZHEIMER'S disease treatment , *SEMANTICS , *PHONOLOGICAL awareness , *SPEECH therapy , *FISHER exact test , *APHASIA , *TREATMENT effectiveness , *CONCEPTUAL structures , *ANOMIA , *ANALYSIS of covariance , *DESCRIPTIVE statistics , *RESEARCH funding - Abstract
An individual's diagnostic subtype may fail to predict the efficacy of a given type of treatment for anomia. Classification by conceptual-semantic impairment may be more informative. This study examined the effects of conceptual-semantic impairment and diagnostic subtype on anomia treatment effects in primary progressive aphasia (PPA) and Alzheimer's disease (AD). At baseline, the picture and word versions of the Pyramids and Palm Trees and Kissing and Dancing tests were used to measure conceptual-semantic processing. Based on norming that was conducted with unimpaired older adults, participants were classified as being impaired on both the picture and word versions (i.e., modality-general conceptual-semantic impairment), the picture version (Objects or Actions) only (i.e., visual-conceptual impairment), the word version (Nouns or Verbs) only (i.e., lexical-semantic impairment), or neither the picture nor the word version (i.e., no impairment). Following baseline testing, a lexical treatment and a semantic treatment were administered to all participants. The treatment stimuli consisted of nouns and verbs that were consistently named correctly at baseline (Prophylaxis items) and/or nouns and verbs that were consistently named incorrectly at baseline (Remediation items). Naming accuracy was measured at baseline, and it was measured at three, seven, eleven, fourteen, eighteen, and twenty-one months. Compared to baseline naming performance, lexical and semantic treatments both improved naming accuracy for treated Remediation nouns and verbs. For Prophylaxis items, lexical treatment was effective for both nouns and verbs, and semantic treatment was effective for verbs, but the pattern of results was different for nouns – the effect of semantic treatment was initially nonsignificant or marginally significant, but it was significant beginning at 11 Months, suggesting that the effects of prophylactic semantic treatment may become more apparent as the disorder progresses. Furthermore, the interaction between baseline Conceptual-Semantic Impairment and the Treatment Condition (Lexical vs. Semantic) was significant for verb Prophylaxis items at 3 and 18 Months, and it was significant for noun Prophylaxis items at 14 and 18 Months. The pattern of results suggested that individuals who have modality-general conceptual-semantic impairment at baseline are more likely to benefit from lexical treatment, while individuals who have unimpaired conceptual-semantic processing at baseline are more likely to benefit from semantic treatment as the disorder progresses. In contrast to conceptual-semantic impairment, diagnostic subtype did not typically predict the treatment effects. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
43. Rendimiento del Test de Denominación de Boston en una población de adultos mayores con queja cognitiva.
- Author
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Lavin, Luisina and Calzolari, Aldo
- Subjects
NEUROPSYCHOLOGICAL tests ,MEDICAL record access control ,EDUCATION ,ANOMY ,OLDER people - Abstract
Copyright of Journal of Applied Cognitive Neuroscience is the property of CORPORACION UNIVERSIDAD DE LA COSTA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
44. ANOMIA Y EXTINCIÓN DE DOMINIO: UNA MIRADA FUNDAMENTADORA A LA FIGURA CONSTITUCIONAL.
- Author
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Vargas Tamayo, Camilo Alfonso
- Subjects
ANOMY ,SOCIAL goals ,CRIMINAL law ,JUSTICE administration ,FORFEITURE - Abstract
Copyright of Derecho Penal y Criminologia is the property of Universidad Externado de Colombia, Departamento de Derecho Penal y Criminologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
45. Anomia: Deciphering Functional Neuroanatomy in Primary Progressive Aphasia Variants.
- Author
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Akhmadullina, Diliara R., Konovalov, Rodion N., Shpilyukova, Yulia A., Fedotova, Ekaterina Yu., and Illarioshkin, Sergey N.
- Subjects
- *
NEUROANATOMY , *VOXEL-based morphometry , *APHASIA , *FRONTAL lobe , *PARIETAL lobe , *SPEECH apraxia - Abstract
Naming decline is one of the most common symptoms of primary progressive aphasia (PPA). Most studies on anomia in PPA are performed without taking into account PPA variants, especially for action naming. Only limited data are available for the neuroanatomical basis of anomia considering differences in the pathogenesis of PPAs. The aim of our study is to investigate the associations between anomia severity for both noun and verb naming and gray matter (GM) atrophy, as well as accompanying functional connectivity (FC) changes in three PPA variants. A total of 17 patients with non-fluent (nfvPPA), 11 with semantic (svPPA), and 9 with logopenic (lvPPA) PPA variants were included in the study and underwent cognitive/naming assessments and brain MRIs. Voxel-based morphometry was performed to evaluate GM volume. A resting-state functional MRI was applied to investigate FC changes in the identified GM areas. The study shows that different brain regions are involved in naming decline in each PPA variant with a predominantly temporal lobe involvement in svPPA, parietal lobe involvement in lvPPA, and frontal lobe involvement in nfvPPA. Separate data for object and action naming in PPA variants are provided. The obtained results mainly correspond to the current understanding of language processing and indicate that the evaluation of language impairments is preferable for each PPA variant separately. A further analysis of larger cohorts of patients is necessary to confirm these preliminary results. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
46. Asynchronous, online spaced-repetition training alleviates word-finding difficulties in aphasia.
- Author
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de Grosbois, John, Canthiya, Lathushikka, Philipp-Muller, Aaron E., Hickey, Natasha K., Hodzic-Santor, Benazir, Heleno, Madeline C., Jokel, Regina, and Meltzer, Jed A.
- Subjects
- *
LEXICAL access , *ONLINE education , *APHASIA - Abstract
Word-finding difficulties for naming everyday objects are often prevalent in aphasia. Traditionally, treating these difficulties has involved repeated drilling of troublesome items with a therapist. Spaced repetition schedules can improve the efficiency of such training. However, spaced repetition in a therapy environment can be both difficult to implement and time-consuming. The current study evaluated the potential utility of automated, asynchronous, online spaced repetition training for the treatment of word-finding difficulties in individuals with aphasia. Twenty-one participants completed a two-week training study, completing approximately 60 minutes per day of asynchronous online drilling. The training items were identified using a pretest, and word-finding difficulties were evaluated both at the end of training (i.e., a post-test) and four weeks later (i.e., a retention test). The trained items were separated into three different spaced-repetition schedules: (1) Short-spacing; (2) Long-spacing; and (3) Adaptive-spacing. At the retention-test, all trained items outperformed non-trained items in terms of accuracy and reaction time. Further, preliminary evidence suggested a potential reaction time advantage for the adaptive-spacing condition. Overall, online, asynchronous spaced repetition training appears to be effective in treating word-finding difficulties in aphasia. Further research will be required to determine if different spaced repetition schedules can be leveraged to enhance this effect. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
47. Outcomes from a pilot dose comparison study of naming therapy in aphasia.
- Author
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Harvey, Sam, Carragher, Marcella, Dickey, Michael Walsh, and Rose, Miranda L.
- Subjects
- *
PILOT projects , *SEMANTICS , *STROKE , *SPEECH therapy , *PHONOLOGICAL awareness , *CONVALESCENCE , *LINGUISTICS , *APHASIA , *TREATMENT effectiveness , *COMPARATIVE studies , *ANOMIA , *DESCRIPTIVE statistics , *RESEARCH funding , *STATISTICAL sampling , *PROMPTS (Psychology) , *DISEASE complications - Abstract
People with aphasia vary considerably in response to aphasia treatments. Treatment dose is likely to be an important factor in understanding treatment response variability and optimising aphasia recovery; however, there is limited empirical evidence to guide dose prescription in post-stroke aphasia rehabilitation. In the present study, we used a novel approach to personalise dose prescription and explored the effect of dose on treatment response in chronic post-stroke aphasia. Examine the effect of providing personalised doses of a cued picture naming treatment (Kendall et al., 2014) on acquisition and maintenance of picture naming outcomes. This pilot study used a multiple-baselines design with follow-up at 4- and 12-weeks with replication across four people with chronic post-stroke anomia. Prior to treatment, a comprehensive battery of cognitive and language tests was completed. Participants then undertook a period of cued picture naming treatment (45-minute sessions, five days per week for three weeks) totalling 15 sessions (11.25 hours). Participants were allocated four picture sets – one each for three treated conditions (low dose, moderate dose, and high dose) and one for an untreated control set. The number of naming opportunities provided per dose condition was calibrated against individuals' pre-treatment picture naming accuracy and speed. Generalised linear mixed effects models were used to evaluate learning effects during treatment, maintenance of these effects, and dose-response relationships. Participants received 99% of prescribed treatment doses (i.e., number of naming opportunities provided over the course of treatment). As anticipated, individual treatment responses varied substantially. Three participants demonstrated significantly improved picture naming accuracy on probed items during treatment, with varying response profiles by participant and dose. All participants were able to name more pictures accurately on a bespoke 298-item object picture naming test following treatment. However, no participant demonstrated significant pre-post treatment gains relative to untreated items, although one person demonstrated improved naming four weeks after treatment for items treated under the high dose condition. Dose-response relationships amongst these participants exhibited a greater number of significant results on naming probes in the high dose condition, possibly suggesting superiority of the high dose condition over lower doses of cued picture naming treatment. Modest treatment effects and variable dose-response relationships were observed. We explore the role of dose, cognitive factors such as self-monitoring abilities, and linguistic factors such as underlying lexical-semantic and phonological processing that may have influenced treatment response in these participants. Avenues for future research are identified. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
48. Anomia in people with Relapsing-Remitting Multiple Sclerosis : investigating the nature and extent of the problem and taking steps toward better assessment and treatment
- Author
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Cordova Luna, Erika, Conroy, Paul, and Muhlert, Nils
- Subjects
Multiple Sclerosis ,Anomia ,Language deficits ,Naming therapy - Abstract
Multiple Sclerosis (MS) is a neurodegenerative inflammatory disease characterised by demyelination and axonal loss in both, white and grey matter. It affects motor, sensory, cognitive and language functions. Language impairments have only recently been studied as a clinical manifestation, with word retrieval deficits as the most common symptoms. Anomia is also the most self-reported language feature between people with MS and even subtle deficits can affect communicative participation and quality of life. This thesis investigated the extent and nature of anomia in people with Relapsing-Remitting (RR) MS through behavioural and imaging analyses and evaluated the use of a word retrieval software-based treatment as a form of self-management of anomic symptoms. In order to explore the scope of anomia in the context of cognitive, linguistic and speech production skills, 151 participants with RR MS were assessed using general cognition tasks and a bespoke picture test which focused on accuracy and latency. Next, in order to understand the factors involved in the anomic symptoms, a wide array of neuropsychological and communication assessments were conducted with the RR MS participants (n=21). Later, the efficacy of a novel word retrieval software-based treatment for anomic symptoms was examined in participants (n=13), which focused on combined accuracy and speed intervention. Finally, grey matter (GM) volumes of 105 participants with RR MS were assessed and compared with healthy individuals as well their relationship with verbal fluency tests outcomes, as a means to a better understanding of the neural nature of verbal fluency in RR MS. Results showed that participants with RR MS often present with anomic symptoms characterised as word retrieval inaccuracy and delayed latency. It was established that anomia could not be fully explained by speech deficits such as dysarthria and that difficulties in naming retrieval may have stemmed from a disruption in the systems of working memory and speed of information processing, and deficits in the semantic access, search and/or memory store. Furthermore, MRI on GM volumes suggested that low scores in verbal fluency tasks showed a general decline in information processing skills. Finally, we observed that word retrieval therapy produced gains in naming accuracy and latency and these could be generalised to connected speech task. However, the speeded therapy did not give an advantage for improving confrontational naming. In conclusion, anomia is a common symptom in RR MS and could be described as a cognitive-communication disorder rather than a pure language deficit. Targeted early interventions could help to improve or maintain language abilities in people with RR-MS which may enhance their quality of life.
- Published
- 2022
49. Salteadores y bandidos en tiempos de la Anarquía Militar. Anomia política, caos económico y auge criminal en el sur peruano a inicios de la República (1824-1845).
- Author
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César Augusto Belan
- Subjects
Bandolerismo ,Anarquía militar ,Perú ,anomia ,siglo XIX ,Latin America. Spanish America ,F1201-3799 - Abstract
En el presente artículo se busca analizar la incidencia criminal en el sur peruano en los primeros años de la República, comparándola además con la etapa anterior tardovirreinal. El estudio se ubica en los departamentos del sur del Perú, fundamentalmente en Arequipa. Se han utilizado como fuente primaria más de mil expedientes de causas criminales del fondo Corte Superior de Justicia del Archivo Regional de Arequipa. Para su formulación se han utilizado los postulados teóricos de la escuela funcionalista de Durkheim y las ideas de Ranajit Guha para ensayar algunas explicaciones sobre la magnitud delictiva en relación con el contexto. En este se ha identificado la relación entre la debilidad institucional de la temprana República, y, sobre todo, la crisis económica acaecida en el contexto de las guerras civiles y la anarquía militar de inicios de la República peruana y el auge entre los ataques a la propiedad, especialmente en formas como el bandolerismo y el abigeato.
- Published
- 2024
- Full Text
- View/download PDF
50. A feasibility study on the use of audio-based ecological momentary assessment with persons with aphasia.
- Author
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Hester, Jack, Le, Ha, Intille, Stephen, and Meier, Erin
- Subjects
ECOLOGICAL momentary assessments (Clinical psychology) ,SMARTWATCHES ,APHASIA ,FEASIBILITY studies ,SOUND recordings - Abstract
We describe a smartphone/smartwatch system to evaluate anomia in individuals with aphasia by using audio-recording-based ecological momentary assessments. The system delivers object-naming assessments to a participant's smartwatch, whereby a prompt signals the availability of images of these objects on the watch screen. Participants attempt to speak the names of the images that appear on the watch display out loud and into the watch as they go about their lives. We conducted a three-week feasibility study with six participants with mild to moderate aphasia. Participants were assigned to either a nine-item (four prompts per day with nine images) or single-item (36 prompts per day with one image each) ecological momentary assessment protocol. Compliance in recording an audio response to a prompt was approximately 80% for both protocols. Qualitative analysis of the participants' interviews suggests that the participants felt capable of completing the protocol, but opinions about using a smartwatch were mixed. We review participant feedback and highlight the importance of considering a population's specific cognitive or motor impairments when designing technology and training protocols. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
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