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Your search keyword '"Anti-HLA-1 antibodies"' showing total 2 results
Start Over Descriptor "Anti-HLA-1 antibodies"
2 results on '"Anti-HLA-1 antibodies"'

1. A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection in renal transplantation

Author

Nicole Wittenbrink, Sabrina Herrmann, Arturo Blazquez-Navarro, Chris Bauer, Eric Lindberg, Kerstin Wolk, Robert Sabat, Petra Reinke, Birgit Sawitzki, Oliver Thomusch, Christian Hugo, Nina Babel, Harald Seitz, and Michal Or-Guil

Subjects
Renal transplantation, Acute cellular rejection, Pre-transplantation risk assessment, Anti-HLA-1 antibodies, Single HLA antigen bead assay, Immune signatures, Immunologic diseases. Allergy, RC581-607
Abstract

Abstract Background Acute cellular rejection (ACR) is associated with complications after kidney transplantation, such as graft dysfunction and graft loss. Early risk assessment is therefore critical for the improvement of transplantation outcomes. In this work, we retrospectively analyzed a pre-transplant HLA antigen bead assay data set that was acquired by the e:KID consortium as part of a systems medicine approach. Results The data set included single antigen bead (SAB) reactivity profiles of 52 low-risk graft recipients (negative complement dependent cytotoxicity crossmatch, PRA

Published
2019
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