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Anticoagulation therapy is an area of high impacts for pharmacists. Anticoagulants (blood thinners) require constant monitoring for renal function, pharmacokinetics, and interactions with other medicines. In some ways, these drugs can be considered a double-edged sword – while they save thousands of lives by preventing and treating strokes, pulmonary embolisms and DVTs, misuse can lead to complications ranging from worrisome to catastrophic. So it is essential that all pharmacists understand the benefits and risks associated with these high-risk medications. Anticoagulation Therapy has become the go-to resource for pharmacists who treat and manage the millions of patients on anticoagulants in both inpatient and outpatient settings. The second edition of this quick reference will continue with its heavy reliance on tables and bulleted lists. The second edition will feature new chapters on mechanical devices and considerations in special populations. The pioneering chapter on anticoagulation reversal will be divided into two chapters with one focusing on agents and one on patient considerations. Also new for this edition: 5 new chapters, 2 new appendixes, 3 updated appendixes.

This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.

Dieser Leitfaden soll den Leser praxisorientiert und in der notwendigen Kürze bei der Behandlung der Patienten mit dem Faktor-Xa-Inhibitor Rivaroxaban unterstützen.

The management of patients committed to long-term oral anticoagulation, such as those with atrial fibrillation at moderate to high risk of stroke, mechanical heart valves, and previous arterial/venous thromboembolism, who are submitted to percutaneous coronary intervention (PCI) has become an issue of increasing importance in the last years. Guidelines/expert consensus papers addressing the complex management of this population, which is estimated to represent about 5 to 10% of all patients referred for PCI, have been recently made available. As underlined in the most recent guidelines for the management of atrial fibrillation issued by the European Society of Cardiology (ESC) however,'guidelines are no substitutes for textbooks'. This pocketbook addresses the key management points and summarises the properties of the stents and the clinical pharmacology of the antithrombotic agents to be used in these patients. It will be a useful guide for clinical and interventional cardiologists, internists, surgeons, primary care doctors, and other physicians who care for these patients.

Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most frequent and devastating adverse drug reactions encountered by physicians. This thoroughly updated fifth edition from international experts Professors Warkentin and Greinacher is the gold standard for accurate diagnosis and management of this cond