1. Determinants of the optimal uptake of sulfadoxine-pyrimethamine doses for intermittent treatment of malaria in pregnancy in urban Nigeria.
- Author
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Adeojo OS and Fayehun O
- Subjects
- Humans, Female, Pregnancy, Nigeria epidemiology, Adult, Cross-Sectional Studies, Young Adult, Adolescent, Urban Population, Sulfadoxine therapeutic use, Sulfadoxine administration & dosage, Pyrimethamine therapeutic use, Pyrimethamine administration & dosage, Malaria prevention & control, Malaria epidemiology, Malaria drug therapy, Antimalarials therapeutic use, Antimalarials administration & dosage, Drug Combinations, Pregnancy Complications, Parasitic prevention & control, Pregnancy Complications, Parasitic drug therapy
- Abstract
Malaria is a leading cause of maternal and child mortality in urban Nigeria. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) during pregnancy can prevent malaria but uptake is suboptimal. This cross-sectional study analyzed secondary data on 1159 urban Nigerian women from the 2015 Malaria Indicator Survey using descriptive statistics and logistic regression. The primary outcome was optimal IPTp-SP uptake (≥ 3 doses). 67% of women took any SP during pregnancy but only 39% took ≥ 3 IPTp-SP doses as recommended. Region and wealth index significantly predicted optimal IPTp-SP uptake while education did not. Women from lower-income regions in the urban areas were less likely to receive optimal IPTp-SP. Strategies to increase IPTp-SP uptake in urban Nigeria should target low-income regions and women of lower socioeconomic status. Logistic regression identified actionable factors for improving antenatal malaria prevention. Optimal IPTp-SP uptake remains suboptimal across urban Nigeria, threatening maternal and child health., (© 2024. The Author(s).)
- Published
- 2024
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