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2. Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson’s disease: a clinical-instrumental study

Author

Cavallieri, Francesco, Campanini, Isabella, Gessani, Annalisa, Budriesi, Carla, Fioravanti, Valentina, Di Rauso, Giulia, Feletti, Alberto, Damiano, Benedetta, Scaltriti, Sara, Guagnano, Noemi, Bardi, Elisa, Corni, Maria Giulia, Rossi, Jessica, Antonelli, Francesca, Cavalleri, Francesca, Molinari, Maria Angela, Contardi, Sara, Menozzi, Elisa, Puzzolante, Annette, Vannozzi, Giuseppe, Bergamini, Elena, Pavesi, Giacomo, Meoni, Sara, Fraix, Valérie, Fraternali, Alessandro, Versari, Annibale, Lusuardi, Mirco, Biagini, Giuseppe, Merlo, Andrea, Moro, Elena, and Valzania, Franco

Published
2023
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3. Author Correction: Long-term effects of subthalamic nucleus deep brain stimulation on speech in Parkinson’s disease

Author

Gessani, Annalisa, Cavallieri, Francesco, Fioravanti, Valentina, Campanini, Isabella, Merlo, Andrea, Di Rauso, Giulia, Damiano, Benedetta, Scaltriti, Sara, Bardi, Elisa, Corni, Maria Giulia, Antonelli, Francesca, Cavalleri, Francesca, Molinari, Maria Angela, Contardi, Sara, Menozzi, Elisa, Fraternali, Alessandro, Versari, Annibale, Biagini, Giuseppe, Fraix, Valérie, Pinto, Serge, Moro, Elena, Budriesi, Carla, and Valzania, Franco

Published
2023
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4. Long-term effects of subthalamic nucleus deep brain stimulation on speech in Parkinson’s disease

Author

Gessani, Annalisa, Cavallieri, Francesco, Fioravanti, Valentina, Campanini, Isabella, Merlo, Andrea, Di Rauso, Giulia, Damiano, Benedetta, Scaltriti, Sara, Bardi, Elisa, Corni, Maria Giulia, Antonelli, Francesca, Cavalleri, Francesca, Molinari, Maria Angela, Contardi, Sara, Menozzi, Elisa, Fraternali, Alessandro, Versari, Annibale, Biagini, Giuseppe, Fraix, Valérie, Pinto, Serge, Moro, Elena, Budriesi, Carla, and Valzania, Franco

Published
2023
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5. Comparing the effects of irradiation with protons or photons on neonatal mouse brain: Apoptosis, oncogenesis and hippocampal alterations

Author

Giovannini, Daniela, Antonelli, Francesca, Casciati, Arianna, De Angelis, Cinzia, Astorino, Maria Denise, Bazzano, Giulia, Fratini, Emiliano, Ampollini, Alessandro, Vadrucci, Monia, Cisbani, Evaristo, Nenzi, Paolo, Picardi, Luigi, Saran, Anna, Marino, Carmela, Mancuso, Mariateresa, Ronsivalle, Concetta, and Pazzaglia, Simonetta

Published
2024
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10. Involvement of Mitochondria in the Selective Response to Microsecond Pulsed Electric Fields on Healthy and Cancer Stem Cells in the Brain

Author

Casciati, Arianna, primary, Taddei, Anna Rita, additional, Rampazzo, Elena, additional, Persano, Luca, additional, Viola, Giampietro, additional, Cani, Alice, additional, Bresolin, Silvia, additional, Cesi, Vincenzo, additional, Antonelli, Francesca, additional, Mancuso, Mariateresa, additional, Merla, Caterina, additional, and Tanori, Mirella, additional

Published
2024
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15. Longitudinal Neuropsychological Assessment of Symptomatic Edema after Subthalamic Nucleus Deep Brain Stimulation Surgery: A Case Series Study

Author

De Ieso, Silvia, primary, Di Rauso, Giulia, additional, Cavallieri, Francesco, additional, Beltrami, Daniela, additional, Marti, Alessandro, additional, Napoli, Manuela, additional, Pascarella, Rosario, additional, Feletti, Alberto, additional, Fioravanti, Valentina, additional, Toschi, Giulia, additional, Rispoli, Vittorio, additional, Antonelli, Francesca, additional, Puzzolante, Annette, additional, Pavesi, Giacomo, additional, Gasparini, Federico, additional, and Valzania, Franco, additional

Published
2023
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18. Longitudinal Neuropsychological Assessment of Symptomatic Edema after Subthalamic Nucleus Deep Brain Stimulation Surgery: A Case Series Study.

Author

De Ieso, Silvia, Di Rauso, Giulia, Cavallieri, Francesco, Beltrami, Daniela, Marti, Alessandro, Napoli, Manuela, Pascarella, Rosario, Feletti, Alberto, Fioravanti, Valentina, Toschi, Giulia, Rispoli, Vittorio, Antonelli, Francesca, Puzzolante, Annette, Pavesi, Giacomo, Gasparini, Federico, and Valzania, Franco

Subjects
DEEP brain stimulation, SUBTHALAMIC nucleus, BRAIN surgery, NEUROPSYCHOLOGICAL tests, CEREBRAL edema, BRAIN imaging
Abstract

Severe non-infectious or non-haemorrhagic brain edema surrounding the electrode represents a rare complication of subthalamic nucleus deep brain stimulation (STN-DBS) surgery. The aim of this study is to report three patients with advanced Parkinson's Disease (PD) who developed symptomatic brain edema after STN-DBS surgery treated with intravenous steroids with a specific profile of reversible cognitive alterations. Patients were both assessed with a comprehensive neuropsychological battery including attention, memory, visuo-spatial and executive tasks. They were also briefly assessed for emotional and behavioural alterations, and for possible limitations in the activities of daily living. Normative data for an Italian population were available for all neuropsychological tests. The patients were firstly assessed before the surgery (baseline) as soon as they became symptomatic for the post-surgery edema and a few more times in follow-up up to ten months. In all patients we observed the resolution of cognitive deficits within six months after surgery with the corresponding reabsorption of edema at brain CT scans. The appearance of post-DBS edema is a fairly frequent and clinically benign event. However, in some rare cases it can be very marked and lead to important clinical—albeit transient—disturbances. These events can compromise, at least from a psychological point of view, the delicate path of patients who undergo DBS and can prolong the post-operative hospital stay. In this setting it could be helpful to perform a brain CT scan in 2–3 days with the aim of detecting the early appearance of edema and treating it before it can constitute a relevant clinical problem. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Cerebrospinal fluid levels of coenzyme Q10 are reduced in multiple system atrophy

Author

Ávila, Asunción, Bayés, Àngels, Botta-Orfila, Teresa, Caballol, Núria, Calopa, Matilde, Campdelacreu, Jaume, Ezquerra, Mario, de Fàbregues, Oriol, Fernández-Santiago, Rubén, Hernández-Vara, Jorge, Jaumà, Serge, Marchese, Domenica, Pagonabarraga, Javier, Pastor, Pau, Planellas, Lluís, Pont-Sunyer, Claustre, Puente, Víctor, Pujol, Montserrat, Saura, Josep, Tartaglia, Gian Gaetano, Tolosa, Eduard, Valldeoriola, Francesc, Compta, Yaroslau, Giraldo, Darly M., Muñoz, Esteban, Antonelli, Francesca, Fernández, Manel, Bravo, Paloma, Soto, Marta, Cámara, Ana, Torres, Ferran, and Martí, María José

Published
2018
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27. Interplay between speech and gait variables in Parkinson's disease patients treated with subthalamic nucleus deep brain stimulation: A long‐term instrumental assessment

Author

Cavallieri, Francesco, primary, Gessani, Annalisa, additional, Merlo, Andrea, additional, Campanini, Isabella, additional, Budriesi, Carla, additional, Fioravanti, Valentina, additional, Di Rauso, Giulia, additional, Feletti, Alberto, additional, Damiano, Benedetta, additional, Scaltriti, Sara, additional, Guagnano, Noemi, additional, Bardi, Elisa, additional, Corni, Maria Giulia, additional, Antonelli, Francesca, additional, Cavalleri, Francesca, additional, Molinari, Maria Angela, additional, Contardi, Sara, additional, Menozzi, Elisa, additional, Puzzolante, Annette, additional, Vannozzi, Giuseppe, additional, Bergamini, Elena, additional, Pavesi, Giacomo, additional, Fraix, Valérie, additional, Meoni, Sara, additional, Fraternali, Alessandro, additional, Versari, Annibale, additional, Lusuardi, Mirco, additional, Biagini, Giuseppe, additional, Pinto, Serge, additional, Moro, Elena, additional, and Valzania, Franco, additional

Published
2023
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28. Design and Implementation of an Accessible 3D Bioprinter: Benchmarking the Performance of a Home-Made Bioprinter against a Professional Bioprinter.

Author

D'Atanasio, Paolo, Fiaschini, Noemi, Rinaldi, Antonio, Zambotti, Alessandro, Cantini, Lorenzo, Mancuso, Mariateresa, and Antonelli, Francesca

Subjects
BIOPRINTING, 3-D printers, CELL growth, CELL survival, PROFESSIONAL employees, CELL culture
Abstract

The tremendous application potential of 3D bioprinting in the biomedical field is witnessed by the ever-increasing interest in this technology over the past few years. In particular, the possibility of obtaining 3D cellular models that mimic tissues with precision and reproducibility represents a definitive advance for in vitro studies dealing with the biological mechanisms of cell growth, death and proliferation and is at the basis of the responses of healthy and pathological tissues to drugs and therapies. However, the impact of 3D bioprinting on research is limited by the high costs of professional 3D bioprinters, which represent an obstacle to the widespread access and usability of this technology. In this work, we present a 3D bioprinter that was developed in-house by modifying a low-cost commercial 3D printer by replacing the default extruder used to print plastic filaments with a custom-made syringe extruder that is suitable for printing bioinks. The modifications made to the 3D printer include adjusting the size of the extruder to accommodate a 1 mL syringe and reducing the extruder's size above the printer. To validate the performance of the home-made bioprinter, some main printing characteristics, the cell vitality and the possibility of bioprinting CAD-designed constructs were benchmarked against a renowned professional 3D bioprinter by RegenHu. According to our findings, our in-house 3D bioprinter was mostly successful in printing a complex glioblastoma tumor model with good performances, and it managed to maintain a cell viability that was comparable to that achieved by a professional bioprinter. This suggests that an accessible open-source 3D bioprinter could be a viable option for research and development (R&D) laboratories interested in pre-commercial 3D bioprinting advancements. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Interplay between speech and gait variables in PD patients treated with STN-DBS: A long-term instrumental assessment

Author

Cavallieri, Francesco, Annalisa, Gessani, Merlo, Andrea, Campanini, Isabella, Budriesi, Carla, Fioravanti, Valentina, DI RAUSO, Giulia, Alberto, Feletti, Benedetta, Damiano, Scaltriti, Sara, Noemi, Guadagno, Bardi, Elisa, Corni, MARIA GIULIA, Antonelli, Francesca, Francesca, Cavalleri, Molinari, MARIA ANGELA, Sara, Contardi, Elisa, Menozzi, Puzzolante, Annette, Vannozzi, Giuseppe, Bergamini, Elena, Pavesi, Giacomo, Valérie, Fraix, Alessandro, Fraternali, Annibale, Versari, Lusuardi, Mirco, Biagini, Giuseppe, Serge, Pinto, Elena, Moro, and Valzania, Franco

Subjects
Parkinson’s Disease, STN-DBS, speech, Gait, deep brain stimulation, levodopa, Parkinson’s Disease, speech, STN-DBS, levodopa, Gait, deep brain stimulation
Published
2023

32. MADAME LAVOISIER AND THE OTHERS: WOMEN IN MARIE-ANNE PAULZE-LAVOISIER'S NETWORK (1771-1836).

Author

ANTONELLI, FRANCESCA

Subjects
POST-apartheid era, SOCIABILITY, INFORMATION sharing, CHEMISTS
Abstract

Known as a translator and illustrator of chemical texts, Marie-Anne Paulze-Lavoisier (1758-1836) has been often represented as the associate of male savants and especially of her husband, the French chemist Antoine-Laurent Lavoisier. This article explores her biography from a different angle and focuses on her trajectories as a secrétaire; namely, someone whose main charge was to store and exchange information by means of writing. The article investigates the presence of women in Paulze-Lavoisier's network before and after Lavoisier's death in 1794. First, it shows that her work as a secrétaire combined a wide set of writing practices with domestic sociability. Then, it examines how other women contributed to her collaboration with Lavoisier. Finally, it analyses how these relationships changed in the post-revolutionary and Napoleonic era, when Paulze-Lavoisier's role as a secrétaire took on a new meaning. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Freezing of Gait in Parkinson’s Disease Patients Treated with Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Long-Term Overview

Author

Di Rauso, Giulia, primary, Cavallieri, Francesco, additional, Campanini, Isabella, additional, Gessani, Annalisa, additional, Fioravanti, Valentina, additional, Feletti, Alberto, additional, Damiano, Benedetta, additional, Scaltriti, Sara, additional, Bardi, Elisa, additional, Corni, Maria Giulia, additional, Antonelli, Francesca, additional, Rispoli, Vittorio, additional, Cavalleri, Francesca, additional, Molinari, Maria Angela, additional, Contardi, Sara, additional, Menozzi, Elisa, additional, Puzzolante, Annette, additional, Rossi, Jessica, additional, Meletti, Stefano, additional, Biagini, Giuseppe, additional, Pavesi, Giacomo, additional, Fraix, Valerie, additional, Lusuardi, Mirco, additional, Fraternali, Alessandro, additional, Versari, Annibale, additional, Budriesi, Carla, additional, Moro, Elena, additional, Merlo, Andrea, additional, and Valzania, Franco, additional

Published
2022
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39. Gendered Touch

Author

Antonelli, Francesca, primary, Romano, Antonella, additional, and Savoia, Paolo, additional

Published
2022
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43. UltraViolet SANitizing System for Sterilization of Ambulances Fleets and for Real-Time Monitoring of Their Sterilization Level

Author

Michelini, Zuleika, primary, Mazzei, Chiara, additional, Magurano, Fabio, additional, Baggieri, Melissa, additional, Marchi, Antonella, additional, Andreotti, Mauro, additional, Cara, Andrea, additional, Gaudino, Alessandro, additional, Mazzalupi, Marco, additional, Antonelli, Francesca, additional, Sommella, Lorenzo, additional, Angeletti, Silvia, additional, Razzano, Elena, additional, Runge, Arnaud, additional, and Petrinca, Paolo, additional

Published
2021
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50. Scrittura, sociabilità e strategie di persuasione: Marie-Anne Paulze-Lavoisier, secrétaire (1758-1836)

Author

Antonelli, Francesca and Beretta, Marco

Subjects
M-STO/05 Storia della scienza e delle tecniche
Abstract

Attraverso uno studio di caso, centrato su Marie-Anne Paulze-Lavoisier (1758-1836), la tesi tratta di pratiche legate all’annotazione e, più in generale, alla registrazione di informazioni su supporti cartacei tra gli anni ’70 del Settecento e gli anni ‘30 dell’Ottocento. Nota oggi come moglie e collaboratrice del chimico Antoine-Laurent Lavoisier (1743-1794), di cui avrebbe promosso le teorie attraverso un’attività di traduttrice e illustratrice, Paulze-Lavoisier è qui presentata nella veste di “secrétaire”, ossia di figura incaricata di mettere per iscritto osservazioni di varia natura. Ci si concentra, in particolare, sui Registres de laboratoire di Lavoisier, 14 quaderni petit in-folio a cui sono affidati i resoconti di esperimenti condotti a Parigi tra il 1772 e il 1788 e che rilevano in misura significativa della mano di lei. Oggetto finora di una storia del pensiero scientifico, interessata alle “idee” in essi contenute, i Registres sono da noi riletti alla luce di un approccio “materiale”, attento alle pratiche e alle condizioni della loro compilazione e del loro riutilizzo nel tempo. Si indagano quindi le funzioni di questi quaderni rispetto alla pratica sperimentale, ricostruendo al contempo i tratti e le evoluzioni del ruolo di segretaria affidato a Paulze-Lavoisier. Il focus su Paulze-Lavoisier permette da un lato a sollevare nuove domande in merito al rapporto tra scrittura delle note, genere e sociabilità ma anche, ad un altro livello, alla cosiddetta “invisibilità” degli assistenti; dall’altro offre la materia per una storia lunga dei Registres, che dai primi gesti in essi da lei operati agli inizi degli anni ’70 del Settecento arriva fino alle manipolazioni a cui sono sottoposti, per sua volontà, nei primi decenni dell’Ottocento., Taking Marie-Anne Paulze-Lavoisier (1758-1836) as a primary case study, this dissertation examines note-taking practices and information management during the long eighteenth-century (1770-1830 circa). Known as the wife and scientific associate of the French chemist Antoine-Laurent Lavoisier (1743-1794), and more notably, as a translator and illustrator of chemical texts on her own right, Paulze-Lavoisier is here presented as a secretaire and namely as someone whose main charge was to store and exchange information by means of writing. I focus, in particular, on the so-called Registres de laboratoire: 14 notebooks containing the accounts of numerous experiments performed by Lavoisier and his associates in Paris between 1772 and 1788 and annotated thoroughly by Paulze-Lavoisier. In contrast to previous historiography, I reassess the meaning of the Registres in the light of the practices by which they were compiled, consulted, and preserved. By tracing Paulze-Lavoisier’s interventions and exploring the material and social conditions in which they were made, I show the role of scribal practices in Lavoisier’s working routine and, at the same time, I retrace her trajectories as a secrétaire. In the last part of the dissertation, I explore the fate of the Registres after Lavoisier’s death in 1794, when Paulze-Lavoisier’s work as a secrétaire took new directions. The broader aim of the thesis is to raise new questions relating to the relationships between note-taking practices, gender, and sociability as well as to the social construction of scientific authority, and the social visibility of scribal helpers and assistants before and after the French Revolution.

Published
2021

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