947 results on '"Antonello, E"'
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2. Combination of US hyperthermia and radiotherapy on a preclinical glioblastoma model
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Gianni Durando, Federica Vurro, Fabio Saba, Aoife M. Ivory, Raphaela de Melo Baesso, Piero Miloro, and Antonello E. Spinelli
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Medicine ,Science - Abstract
Abstract In this work the effect of combining ultrasound (US) hyperthermia (HT) with radiotherapy (RT) was investigated. The treatment was applied to a GBM xenograft nude mouse model obtained by injecting $$2 \times 10^{6}$$ 2 × 10 6 U87 luc+ cells. The combined treatment group received 6 Gy and HT at $$43^\circ$$ 43 ∘ for 8 min. The ultrasound field was generated by a closed-loop computationally controlled system, consisting of a High Intensity Focused Ultrasound (HIFU) transducer with centre frequency 3.57 MHz, a power amplifier, a function generator and a MATLAB controller. A mechanical cone adaptor has been designed to use the HIFU beam at a pre-defined post-focal distance. Two thermocouples were placed between the mechanical cone and the mice skin to measure and control the temperature during the HT treatment. Radiotherapy was carried out by using a dedicated small animal image guided radiotherapy system. Measurements of tumor volume performed with a caliper showed good tumor control for the RT-HT group with respect to the RT or control groups for up to 21 days after treatment. The mean value of the normalized (before therapy) tumor volume was almost equal to 0.5 for two weeks after treatment with an increase to 1.5 at sacrifice. The control and HT groups showed a higher value of about 1.5 during the first two weeks and 3.5 at the end of the follow-up period. We concluded that the use of HT as a radiosensitizer can improve the outcome for glioblastoma treatments.
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- 2024
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3. Metabolomic profiling of Prader-Willi syndrome compared with essential obesity
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Antonello E. Rigamonti, Elisa Polledri, Chiara Favero, Diana Caroli, Adele Bondesan, Graziano Grugni, Stefania Mai, Silvano G. Cella, Silvia Fustinoni, and Alessandro Sartorio
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Prader-Willi syndrome ,essential obesity ,metabolomics ,biochemical pathways ,lipid metabolism ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
IntroductionPrader-Willi syndrome (PWS) is a rare disease, which shows a peculiar clinical phenotype, including obesity, which is different from essential obesity (EOB). Metabolomics might represent a valuable tool to reveal the biochemical mechanisms/pathways underlying clinical differences between PWS and EOB. The aim of the present (case-control, retrospective) study was to determine the metabolomic profile that characterizes PWS compared to EOB.MethodsA validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) targeted metabolomic approach was used to measure a total of 188 endogenous metabolites in plasma samples of 32 patients with PWS (F/M = 23/9; age: 31.6 ± 9.2 years; body mass index [BMI]: 42.1 ± 7.0 kg/m2), compared to a sex-, age- and BMI-matched group of patients with EOB (F/M = 23/9; age: 31.4 ± 6.9 years; BMI: 43.5 ± 3.5 kg/m2).ResultsBody composition in PWS was different when compared to EOB, with increased fat mass and decreased fat-free mass. Glycemia and HDL cholesterol were higher in patients with PWS than in those with EOB, while insulinemia was lower, as well as heart rate. Resting energy expenditure was lower in the group with PWS than in the one with EOB, a difference that was missed after fat-free mass correction. Carrying out a series of Tobit multivariable linear regressions, adjusted for sex, diastolic blood pressure, and C reactive protein, a total of 28 metabolites was found to be associated with PWS (vs. non-PWS, i.e., EOB), including 9 phosphatidylcholines (PCs) ae, 5 PCs aa, all PCs aa, 7 lysoPCs a, all lysoPCs, 4 acetylcarnitines, and 1 sphingomyelin, all of which were higher in PWS than EOB.ConclusionsPWS exhibits a specific metabolomic profile when compared to EOB, suggesting a different regulation of some biochemical pathways, fundamentally related to lipid metabolism.
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- 2024
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4. Forcing Seasonality of influenza-like epidemics with daily Solar resonance
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Nicastro, F., Sironi, G., Antonello, E., Bianco, A., Biasin, M., Brucato, J. R., Ermolli, I., Pareschi, G., Salvati, M., Tozzi, P., Trabattoni, D., and Clerici, M.
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Quantitative Biology - Other Quantitative Biology - Abstract
Seasonality of acute viral respiratory diseases is a well-known and yet not fully understood phenomenon. Several models have been proposed to explain the regularity of yearly recurring outbreaks and the phase-differences observed at different latitudes on Earth. Such models take into account known internal causes, primarily the periodic emergence of new virus variants that evade the host immune response. Yet, this alone, is generally unable to explain the regularity of recurrences and the observed phase-differences. Here we show that seasonality of viral respiratory diseases, as well as its distribution with latitude on Earth, can be fully explained by the virucidal properties of UV-B and A Solar photons through a daily, minute-scale, resonant forcing mechanism. Such an induced periodicity can last, virtually unperturbed, from tens to hundreds of cycles, and even in presence of internal dynamics (host's loss of immunity) much slower than seasonal will, on a long period, generate seasonal oscillations., Comment: Accepted for publication by iScience. This version has been modified according to referee's comments. Models for the SARS-CoV-2 epidemic have been updated to model the Italian data from 24 February 2020 through 21 August 2020
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- 2020
5. Solar UV$-$B$/$A radiation is highly effective in inactivating SARS$-$CoV$-$2
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Nicastro, F., Sironi, G., Antonello, E., Bianco, A., Biasin, M., Brucato, J. R., Ermolli, I., Pareschi, G., Salvati, M., Tozzi, P., Trabattoni, D., and Clerici, M.
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Quantitative Biology - Populations and Evolution ,Physics - Atmospheric and Oceanic Physics - Abstract
Solar UV$-$C photons do not reach Earth's surface, but are known to be endowed with germicidal properties that are also effective on viruses. The effect of softer UV$-$B and UV$-$A photons, which copiously reach the Earth's surface, on viruses are instead little studied, particularly on single$-$stranded RNA viruses. Here we combine our measurements of the action spectrum of Covid$-$19 in response to UV light, Solar irradiation measurements on Earth during the SARS$-$CoV$-$2 pandemics, worldwide recorded Covid$-$19 mortality data and our 'Solar$-$Pump' diffusive model of epidemics to show that (a) UV$-$B$/$A photons have a powerful virucidal effect on the single$-$stranded RNA virus Covid$-$19 and that (b) the Solar radiation that reaches temperate regions of the Earth at noon during summers, is sufficient to inactivate 63\perc of virions in open$-$space concentrations (1.5 x 103 TCID50$/$mL, higher than typical aerosol) in less than 2 min. We conclude that the characteristic seasonality imprint displayed world$-$wide by the SARS$-$Cov$-$2 mortality time$-$series throughout the diffusion of the outbreak (with temperate regions showing clear seasonal trends and equatorial regions suffering, on average, a systematically lower mortality), might have been efficiently set by the different intensity of UV$-$B$/$A Solar radiation hitting different Earth's locations at different times of the year. Our results suggest that Solar UV$-$B$/$A play an important role in planning strategies of confinement of the epidemics, which should be worked out and set up during spring$/$summer months and fully implemented during low$-$solar$-$irradiation periods., Comment: 11 pages + 3 pages supplementary information
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- 2020
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6. Cytotoxicity of PEG-Coated Gold and Gold–Iron Alloy Nanoparticles: ROS or Ferroptosis?
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Clara M. G. de Faria, Michael Bissoli, Riccardo Vago, Antonello E. Spinelli, and Vincenzo Amendola
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nanomedicine ,laser ablation in liquid ,nanoalloys ,cytotoxicity ,biocompatibility ,Chemistry ,QD1-999 - Abstract
Nanomedicine relies on the exploitation of nanoscale constructs for therapeutic and diagnostic functions. Gold and gold–iron alloy nanoparticles (NPs) are two examples of nanomaterials with favorable features for use in nanomedicine. While gold NPs have been studied extensively in the last decades, they are not biodegradable. Nonetheless, biodegradation was recently observed in gold alloys with iron obtained using laser ablation in liquid (LAL). Hence, there is a significant interest in the study of the biological effects of gold and gold–iron alloy nanoparticles, starting from their tolerability and cytotoxicity. In this study, these two classes of NPs, obtained via LAL and coated with biocompatible polymers such as polyethylene glycol, were investigated in terms of their cytotoxicity in fibroblasts, prostate cancer cells (PC3) and embryonic kidney cells (HEK). We also explored the effects of different synthetic procedures, stabilizing additives, and the possible mechanisms behind cell mortality such as the formation of reactive oxygen species (ROS) or ferroptosis. NPs larger than 200 nm were associated with lower cell tolerability. The most tolerable formulations were pure PEG-Au NPs, followed by PEG-Au–Fe NPs with a hydrodynamic size < 50 nm, which displayed a toxicity of only 20% in fibroblasts after 72 h of incubation. In addition, tumor cells and highly proliferating HEK cells are more sensitive to the NPs than fibroblasts. However, a protective effect of catalase was found for cells incubated with PEG-Au–Fe NPs, indicating an important role of hydrogen peroxide in alloy NP interactions with cells. These results are crucial for directing future synthetic efforts for the realization of biocompatible Au NPs and biodegradable and cytocompatible Au–Fe alloy NPs. Moreover, the correlation of the cytocompatibility of NPs with ROS and ferroptosis in cells is of general interest and applicability to other types of nanomaterials.
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- 2023
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7. Metabolomic profiling of Prader-Willi syndrome compared with essential obesity
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Rigamonti, Antonello E., primary, Polledri, Elisa, additional, Favero, Chiara, additional, Caroli, Diana, additional, Bondesan, Adele, additional, Grugni, Graziano, additional, Mai, Stefania, additional, Cella, Silvano G., additional, Fustinoni, Silvia, additional, and Sartorio, Alessandro, additional
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- 2024
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8. Effects of Melatonin on Exercise-Induced Oxidative Stress in Adults with Obesity Undergoing a Multidisciplinary Body Weight Reduction Program.
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Rigamonti, Antonello E., Rubino, Federico M., Caroli, Diana, Bondesan, Adele, Mai, Stefania, Cella, Silvano G., Centofanti, Lucia, Paroni, Rita, and Sartorio, Alessandro
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WEIGHT loss , *NEUTROPHIL lymphocyte ratio , *BODY mass index , *GLYCOSYLATED hemoglobin , *BLOOD sugar - Abstract
Background: Obesity is characterized by increased oxidative stress, which, in a vicious circle, promotes chronic low-grade inflammation. Melatonin, a well-documented antioxidant, might be useful as a supplement to enhance the cardiometabolic benefits of any body weight reduction program (BWRP). Objectives/Methods: The present study aimed to evaluate the post-exercise oxidative stress and inflammation in a group of subjects with obesity treated with melatonin (2 mg/die) or placebo, undergoing a 2-week BWRP, with the administration of a single bout of acute exercise at the start and the end of the protocol (G1–G15). Results: Eighteen adults with obesity were enrolled and distributed to the two arms of the study: the melatonin group (F/M: 7/2; age: 27.8 ± 5.6 years; body mass index [BMI]: 43.0 ± 4.9 kg/m2) and the placebo group (F/M: 6/3; age: 28.8 ± 5.0 years; BMI: 42.8 ± 4.0 kg/m2). BWRP induced a decrease in BMI and waist circumference (WC) in both groups; plasma glucose, blood glycated hemoglobin (HbA1c), and neutrophil to lymphocyte ratio (NLR) were reduced only in the placebo group. Importantly, plasma biological antioxidant potential (BAP) increased throughout BWRP. Paradoxically, melatonin enhanced post-exercise production of plasma derivatives of reactive oxygen metabolites (d-ROMs) and erythrocytic glutathionyl-Hb (HbSSG) (at G1 and G15). Finally, differently from the placebo group, melatonin-treated subjects did not exhibit the BWRP-induced decrease in plasma levels of interleukin-6 (IL-6), before and after exercise, at the end of two weeks (G15). Conclusions: Melatonin is presumably an antioxidant with "conditional" prooxidant actions. The use of melatonin as a supplement in subjects with obesity might be deleterious due to the abolishment of BWRP-induced cardiometabolic benefits. [ABSTRACT FROM AUTHOR]
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- 2024
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9. RaCHy-Radiotherapy Coupled with Hyperthermia-18HLT06 EURAMET EMPIR Project.
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Giovanni Durando, Piero Miloro, Volker Wilkens, Baki Karaboce, Jacco de Pooter, Gerard C. Van Rhoon, Gail ter Haar, Barbara Caccia, Antonello E. Spinelli, Antonia G. Denkova, and Roeland Dijkema
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- 2019
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10. Will undocumented migrants contribute to change epidemiology, presentation and pharmacologic treatment of diabetes in Western countries?
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Fiorini, Gianfrancesco, Milani, Silvano, Pincelli, Angela I., Calella, Damiano, Galliani, Silvia, Badalamenti, Silvia, Rigamonti, Antonello E., Marazzi, Nicoletta, Sartorio, Alessandro, and Cella, Silvano G.
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- 2020
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11. Understanding the effects of air pollution on neurogenesis and gliogenesis in the growing and adult brain
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Boda, Enrica, Rigamonti, Antonello E, and Bollati, Valentina
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- 2020
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12. To fake or not to fake: An empirical investigation on the fine art market
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Scorcu, Antonello E., Vici, Laura, and Zanola, Roberto
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- 2021
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13. Bonaparte and the astronomers of Brera Observatory
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Antonello, E.
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Physics - History and Philosophy of Physics ,Physics - Popular Physics - Abstract
In Northern Italy, between 1796 and 1814, Napoleon Bonaparte formed a Republic, and then a Kingdom, controlled by France. Milan was the capital of the State, and the Brera Palace was the main cultural centre, as regards both the arts and the sciences. Bonaparte probably intended to strengthen this characteristic of Brera, aiming at increasing its Italian and European relevance. We will discuss in detail in which way he interacted with the astronomers of Brera Observatory, and in particular with Barnaba Oriani, that was considered the local main representative of the 'republique des lettres', that is, the world of literature, arts and sciences. We propose a possible reconstruction of the effects of those complicated historical events on the Italian astronomy and on its relations with the European one., Comment: 22 pages
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- 2014
14. Water-filled telescopes
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Antonello, E.
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Physics - History and Philosophy of Physics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Popular Physics - Abstract
In this short note we discuss the case of the thought experiments on water-filled telescopes and their realizations during 18th and 19th century. The story of those instruments shows that the scientific progress occurs in a curious way, since there was no stringent reason for the construction of a water-filled telescope., Comment: 7 pages; to appear in the proceedings of the Conference for the tercentenary of the birth R.G. Boscovich, Pavia, Italy, Sept. 2011
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- 2014
15. A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
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Antonello E. Spinelli, Andrea Bresolin, Stefania Zuppone, Laura Perani, Giuseppe Fallara, Nadia Di Muzio, Riccardo Vago, Claudio Fiorino, and Cesare Cozzarini
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Animal model ,Radiation cystitis ,Bladder wall thickness ,Radiotherapy ,Ultrasound imaging ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim seems promising, but is still relatively unexplored. A method using ultrasound for bladder wall thickness quantification in rats was developed and applied to measure early radiation-induced bladder wall thickness changes. Methods Two groups (n = 9 each) of female Fischer rats were treated with a single radiation dose of 25–30 and 35–40 Gy respectively, using an image-guided micro-irradiator; six untreated rats were monitored as a control group. Empty, half-filled and fully-filled bladder volumes were determined for four non-irradiated rats by measuring axes from ultrasound 3D-images and applying the ellipsoid formula. Mean bladder wall thickness was estimated for both ventral and dorsal bladder sides through the measurement of the bladder wall area along a segment of 4 mm in the central sagittal scan, in order to minimize operator-dependence on the measurement position. Ultrasound acquisitions of all fully-filled rat bladders were also acquired immediately before, and 4 and 28 days after irradiation. Mean bladder wall thickness normalized to the baseline value and corrected for filling were then used to evaluate acute bladder wall thickening and to quantify the dose–effect. Results The relationship between mean bladder wall thickness and volume in unirradiated rats showed that for a bladder volume > 1.5 mL the bladder wall thickness is almost constant and equal to 0.30 mm with variations within ± 15%. The average ratios between post and pre irradiation showed a dose–effect relationship. Bladder wall thickening was observed for the 25–30 Gy and 35–40 Gy groups in 2/9 (22%) and 5/9 (56%) cases at day 4 and in 4/9 (44%) and 8/9 (89%) cases at day 28, respectively. The two groups showed significantly different bladder wall thickness both relative to the control group (p
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- 2020
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16. Effects of an acute bout of exercise on circulating extracellular vesicles: tissue-, sex-, and BMI-related differences
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Rigamonti, Antonello E., Bollati, Valentina, Pergoli, Laura, Iodice, Simona, De Col, Alessandra, Tamini, Sofia, Cicolini, Sabrina, Tringali, Gabriella, De Micheli, Roberta, Cella, Silvano G., and Sartorio, Alessandro
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- 2020
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17. Cultural Astronomy and Archaeoastronomy: an Italian Experience
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Antonello, E.
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Physics - History and Philosophy of Physics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Popular Physics - Abstract
A brief review is given of some recent positive developments regarding the reception of archaeoastronomy by the archaeological institutions in Italy. Discussions and problems that are currently going on in this field are also mentioned, such as the separation of the scientific and humanistic disciplines (i.e. the two cultures problem). Suggestions based on contemporary philosophy are also reported. Finally, sky-gazing is proposed as the place where the two cultures could meet, since, taking Plato into account, sky-gazing could be considered the mom of the human knowledge, and of the scientific and humanistic disciplines., Comment: 6 pages; SEAC 2012 conference on Ancient Cosmologies and Modern Prophets
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- 2013
18. On the Possibility of an Astronomical Perspective in the Study of Human Evolution
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Antonello, E.
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Physics - Popular Physics ,Astrophysics - Earth and Planetary Astrophysics ,Physics - History and Philosophy of Physics - Abstract
The Sapient Paradox is the apparently unexplainable time delay of several ten thousand years following the arrival of Homo sapiens in Asia and Europe and before the introduction of impressive innovations with the agricultural revolution. Renfrew (2007) has suggested that the solution of the paradox has to do with changes in modes of thought that occurred with sedentism. According to Renfrew, this is a subject of study for cognitive archaeology where the final goal would be to understand the formation of the human mind. Several scholars, however, affirm that climatic change was crucial to such a revolution as it would have been very difficult to develop agriculture during the Palaeolithic. In other words, sedentism was not justified during the ice age, and that may be the solution to the paradox. It is widely accepted that climate variations were due to so-called orbital forcing, the slow periodic changes of orbital parameters of the Earth (known also as the Milankovitch theory). These and other astronomical effects on the climate are discussed along with the consequent impact on human evolution. The question then rises as to whether or not it is possible to adopt an astronomical perspective instead of (or complementary to) the cognitive archaeological one. Such would be possible by adopting a different point of reference (that is, from outside), and a non-anthropocentric approach., Comment: 6 pages, 2 figures; SEAC 2012 conference on Ancient Cosmologies and Modern Prophets
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- 2013
19. The PLATO 2.0 Mission
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Rauer, H., Catala, C., Aerts, C., Appourchaux, T., Benz, W., Brandeker, A., Christensen-Dalsgaard, J., Deleuil, M., Gizon, L., Goupil, M. -J., Güdel, M., Janot-Pacheco, E., Mas-Hesse, M., Pagano, I., Piotto, G., Pollacco, D., Santos, N. C., Smith, A., -C., J., Suárez, Szabó, R., Udry, S., Adibekyan, V., Alibert, Y., Almenara, J. -M., Amaro-Seoane, P., Eiff, M. Ammler-von, Asplund, M., Antonello, E., Ball, W., Barnes, S., Baudin, F., Belkacem, K., Bergemann, M., Bihain, G., Birch, A. C., Bonfils, X., Boisse, I., Bonomo, A. S., Borsa, F., Brandão, I. M., Brocato, E., Brun, S., Burleigh, M., Burston, R., Cabrera, J., Cassisi, S., Chaplin, W., Charpinet, S., Chiappini, C., Church, R. P., Csizmadia, Sz., Cunha, M., Damasso, M., Davies, M. B., Deeg, H. J., DÍaz, R. F., Dreizler, S., Dreyer, C., Eggenberger, P., Ehrenreich, D., Eigmüller, P., Erikson, A., Farmer, R., Feltzing, S., Fialho, F. de Oliveira, Figueira, P., Forveille, T., Fridlund, M., García, R. A., Giommi, P., Giuffrida, G., Godolt, M., da Silva, J. Gomes, Granzer, T., Grenfell, J. L., Grotsch-Noels, A., Günther, E., Haswell, C. A., Hatzes, A. P., Hébrard, G., Hekker, S., Helled, R., Heng, K., Jenkins, J. M., Johansen, A., Khodachenko, M. L., Kislyakova, K. G., Kley, W., Kolb, U., Krivova, N., Kupka, F., Lammer, H., Lanza, A. F., Lebreton, Y., Magrin, D., Marcos-Arenal, P., Marrese, P. M., Marques, J. P., Martins, J., Mathis, S., Mathur, S., Messina, S., Miglio, A., Montalban, J., Montalto, M., Monteiro, M. J. P. F. G., Moradi, H., Moravveji, E., Mordasini, C., Morel, T., Mortier, A., Nascimbeni, V., Nelson, R. P., Nielsen, M. B., Noack, L., Norton, A. J., Ofir, A., Oshagh, M., Ouazzani, R. -M., Pápics, P., Parro, V. C., Petit, P., Plez, B., Poretti, E., Quirrenbach, A., Ragazzoni, R., Raimondo, G., Rainer, M., Reese, D. R., Redmer, R., Reffert, S., Rojas-Ayala, B., Roxburgh, I. W., Salmon, S., Santerne, A., Schneider, J., Schou, J., Schuh, S., Schunker, H., Silva-Valio, A., Silvotti, R., Skillen, I., Snellen, I., Sohl, F., Sousa, S. G., Sozzetti, A., Stello, D., Strassmeier, K. G., Švanda, M., Szabó, Gy. M., Tkachenko, A., Valencia, D., van Grootel, V., Vauclair, S. D., Ventura, P., Wagner, F. W., Walton, N. A., Weingrill, J., Werner, S. C., Wheatley, P. J., and Zwintz, K.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
PLATO 2.0 has recently been selected for ESA's M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets like ours, including potentially habitable planets? The PLATO 2.0 instrument consists of 34 small aperture telescopes (32 with 25 sec readout cadence and 2 with 2.5 sec candence) providing a wide field-of-view (2232 deg2) and a large photometric magnitude range (4-16 mag). It focusses on bright (4-11 mag) stars in wide fields to detect and characterize planets down to Earth-size by photometric transits, whose masses can then be determined by ground-based radial-velocity follow-up measurements. Asteroseismology will be performed for these bright stars to obtain highly accurate stellar parameters, including masses and ages. The combination of bright targets and asteroseismology results in high accuracy for the bulk planet parameters: 2%, 4-10% and 10% for planet radii, masses and ages, respectively. The planned baseline observing strategy includes two long pointings (2-3 years) to detect and bulk characterize planets reaching into the habitable zone (HZ) of solar-like stars and an additional step-and-stare phase to cover in total about 50% of the sky. PLATO 2.0 will observe up to 1,000,000 stars and detect and characterize hundreds of small planets, and thousands of planets in the Neptune to gas giant regime out to the HZ. It will therefore provide the first large-scale catalogue of bulk characterized planets with accurate radii, masses, mean densities and ages. This catalogue will include terrestrial planets at intermediate orbital distances, where surface temperatures are moderate. Coverage of this parameter range with statistical numbers of bulk characterized planets is unique to PLATO 2.0., Comment: 63 pages, 17 figures, submitted to Experimental Astronomy (ExA)
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- 2013
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20. Astronomical orientations in sanctuaries of Daunia
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Antonello, E., Polcaro, V. F., Sisto, A. M Tunzi, and LoZupone, M.
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Physics - History and Philosophy of Physics ,Physics - Popular Physics - Abstract
Prehistoric sanctuaries of Daunia date back several thousand years. During the Neolithic and Bronze Age the farmers in that region dug hypogea and holes whose characteristics suggest a ritual use. In the present note we summarize the results of the astronomical analysis of the orientation of the row holes in three different sites, and we point out the possible use of the setting of the stars of Centaurus. An interesting archaeological confirmation of an archaeoastronomical prediction is also reported., Comment: 7 pages, 7 figures
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- 2013
21. Prehistoric sanctuaries in Daunia
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Antonello, E., Polcaro, V. F., Tunzi, A. M., and Zupone, M. Lo
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Physics - History and Philosophy of Physics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Popular Physics - Abstract
Daunia is a region in northern Apulia with many interesting archaeological sites, particularly of the Neolithic and Bronze Age. Beginning from the fifth millennium BC, the farmers living in the wide plain of Daunia dug hypogea and holes in sites that could be considered prehistoric sanctuaries. The characteristics of the rows of holes indicate a ritual use, and the archaeologists tend to exclude other applications, such as post holes and cultivations. The rows have possibly an astronomical orientation, and in the sanctuary discovered near Ordona, some stars of the Centaurus-Crux group (may be alpha Centauri itself) could have been used as targets. In past centuries, astronomers and scholars have remarked this spectacular region of the sky, and its possible relevance for the ancient civilizations was pointed out for example by G.V. Schiaparelli in 1903. In his work on the astronomy in the Old Testament, he mentioned in particular the observations of the astronomer W.S. Jacob and of other scholars. It would be probably worth to make simulations in order to reproduce the 'Jacob effect', that is the diffused light (a sort of faint twilight) produced by such very rich stellar region of the sky., Comment: 6 pages, 6 figures
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- 2013
22. The myths of the Bear
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Antonello, E.
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Physics - Popular Physics ,Physics - History and Philosophy of Physics - Abstract
Following previous works on ancient myths in Greek and Latin literature regarding Ursa Major, and the possible relation with the ancient shape of the constellation, we discuss further this case in the light of the evolution of Homo sapiens and the ethnographic records of populations of Eurasia and North America., Comment: 13 pages, 5 figures
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- 2013
23. Boscovich and the Brera Observatory
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Antonello, E.
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Physics - History and Philosophy of Physics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
In the mid 18th century both theoretical and practical astronomy were cultivated in Milan by Barnabites and Jesuits. In 1763 R.G. Boscovich was appointed to the chair of mathematics of the University of Pavia in the Duchy of Milan, and the following year he designed an observatory for the Jesuit Collegium of Brera. The Specola was built in 1765 and it became quickly one of the main European observatories. We discuss the relation between Boscovich and Brera in the framework of a short biography. An account is given of the initial research activity in the Specola, of the departure of Boscovich from Milan in 1773 and his coming back just before his death., Comment: 8 pages
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- 2013
24. Cytotoxicity of PEG-Coated Gold and Gold–Iron Alloy Nanoparticles: ROS or Ferroptosis?
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de Faria, Clara M. G., primary, Bissoli, Michael, additional, Vago, Riccardo, additional, Spinelli, Antonello E., additional, and Amendola, Vincenzo, additional
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- 2023
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25. Robustness of Distinctive Facial Features in Prader-Willi Syndrome: A Stereophotogrammetric Analysis and Association with Clinical and Biochemical Markers in Adult Individuals
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Claudia Dolci, Antonello E. Rigamonti, Annalisa Cappella, Daniele M. Gibelli, Graziano Grugni, Diana Caroli, Chiarella Sforza, and Alessandro Sartorio
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Prader-Willi syndrome ,adult ,facial features ,anthropometry ,stereophotogrammetry ,Biology (General) ,QH301-705.5 - Abstract
Background: Prader-Willi syndrome (PWS) is a rare genomic imprinting disorder associated to a complex neurodevelopmental phenotype and a distinctive facial appearance. The study investigated the relationships between the quantitative facial dysmorphism in PWS and clinical and biochemical markers of the disease and its treatment. Methods: Facial images of 15 Caucasian adult individuals with PWS (8 males, 42 ± 5 years; 7 females, 37 ± 8 years; BMI 38.87 ± 8.92 kg/m2) were acquired through stereophotogrammetry. From the 3D coordinates of 38 landmarks, linear distances and angles were calculated; they were expressed as z-score values by referring to 403 healthy subjects matched for age and sex and compared by Student’s t-test with Bonferroni correction for multiple testing. Patients underwent auxological and biochemical assessment of endocrine/metabolic dysfunction and nocturnal respiratory function. An exploratory correlation analysis was performed to investigate their associations with the facial phenotype; uncorrected p-values were used. Results and Conclusions: Individuals with PWS showed decreased bifrontal diameter, facial depths, palpebral fissures, mandibular ramus length, lower vermillion height, and modified relative position of exocanthia and nasion. Since these characteristics did not show any associations with clinical and biochemical markers of PWS, they could constitute robust distinctive facial features and contribute to the diagnosis of the disorder. Individuals with PWS showed also a larger mandibular width with smaller gonial angles, thinner upper vermillion, greater inclination of the orbit relative to the Frankfurt plane, and a smaller angle of the auricles versus the facial midplane. Relationships between these facial anthropometric features and body composition, glucidic metabolism indexes, nocturnal hypoxemia episodes, or duration of GH treatment were found, suggesting their potentially useful role in the clinical monitoring and management of the disease. However, they need to be confirmed by subsequent dedicated studies.
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- 2022
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26. Probable nonradial g-mode pulsation in early A-type stars
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Antonello, E., Mantegazza, L., Rainer, M., and Miglio, A.
- Subjects
Astrophysics - Abstract
A survey for line profile variability in early A-type stars has been performed in order to detect nonradial pulsation signatures. The star HR 6139, with spectral type A2V and estimated T_eff=8800 K, shows evident line profile variations that can be explained by oscillations in prograde g-modes. This feature and the known photometric variability are similar to those observed in the Slowly Pulsating B-type stars. However HR 6139 is much cooler than the cool border of the instability strip of such variables, and it is hotter than the blue edge of the delta Scuti instability strip. There are indications of a tiny variability also in other four objects, whose nature is not yet clear., Comment: 4 pages, 5 figures; accepted for publication in A&A (letter)
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- 2005
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27. GHRH plus arginine and arginine administration evokes the same ratio of GH isoforms levels in young patients with Prader-Willi syndrome
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Rigamonti, Antonello E., Crinò, Antonino, Bocchini, Sarah, Convertino, Alessio, Bidlingmaier, Martin, Haenelt, Michael, Tamini, Sofia, Cella, Silvano G., Grugni, Graziano, and Sartorio, Alessandro
- Published
- 2018
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28. Acute administration of capsaicin increases resting energy expenditure in young obese subjects without affecting energy intake, appetite, and circulating levels of orexigenic/anorexigenic peptides
- Author
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Rigamonti, Antonello E., Casnici, Claudia, Marelli, Ornella, De Col, Alessandra, Tamini, Sofia, Lucchetti, Elisa, Tringali, Gabriella, De Micheli, Roberta, Abbruzzese, Laura, Bortolotti, Mauro, Cella, Silvano G., and Sartorio, Alessandro
- Published
- 2018
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29. Photodynamic Therapy Using Cerenkov and Radioluminescence Light
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Antonello E. Spinelli and Federico Boschi
- Subjects
photodynamic therapy ,Cerenkov radiation ,radioluminescence ,nano particles ,photosensitizer ,Physics ,QC1-999 - Abstract
In this short review the potential use of Cerenkov radiation and radioluminescence as internal sources for Photodynamic therapy (PDT) is discussed. PDT has been developed over the course of more than 100 years and is based on the induced photo conversion of a drug called photosensitizer (PS) that triggers the production of cytotoxic reactive oxygen species (ROS) leading to the killing of the cells. In order to overcome the problem of light penetration in the tissues, different solutions were proposed in the past. The use of radioisotopes like: 18F, 64Cu, 90Y, 177Lu as internal light sources increase the light fluence at the PS compared to an external source, resulting in a larger cytotoxic effect.
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- 2021
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30. The Age-Dependent Increase of Metabolic Syndrome Requires More Extensive and Aggressive Non-Pharmacological and Pharmacological Interventions: A Cross-Sectional Study in an Italian Cohort of Obese Women
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Antonello E. Rigamonti, Sabrina Cicolini, Sofia Tamini, Diana Caroli, Silvano G. Cella, and Alessandro Sartorio
- Subjects
Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Background. Metabolic syndrome is a combination of cardiovascular risk factors (i.e., visceral obesity, dyslipidaemia, glucose intolerance, and hypertension), which entails critical issues in terms of medical management and public health. Methods. The aim of the present cross-sectional study was to investigate the age-related changes of the single IDF (International Diabetes Federation) diagnostic criteria for metabolic syndrome (waist circumference, WC; high-density lipoprotein cholesterol, HDL-C; triglycerides; glucose; systolic and diastolic blood pressure, SBP and DBP) in a large population of (Italian) obese women (n = 1.000; body mass index, BMI >30 kg/m2; age: 18–83 yrs), subdivided into two subgroups depending on the presence (n = 630) or absence (n = 370) of metabolic syndrome. Parallelly, the percentages of treatment with hypolipidaemic drugs, hypoglycaemics, and antihypertensives and, among the treated subjects, of control of the underlying condition in accordance with the cut-offs of IDF criteria for dyslipidaemia, hyperglycaemia, and hypertension were determined over six age ranges (i.e., 18–30, 31–40, 41–50, 51–60, 61–70, and > 70 yrs). Results. The prevalence of metabolic syndrome increased with advancing age. In the subgroup with metabolic syndrome, an age-dependent increase in HDL-C, glycaemia, and SBP occurred, while the visceral adiposity was stable. In the same subgroup, triglycerides and DBP decreased age-dependently. In the subgroup without metabolic syndrome, an age-dependent increase in WC, HDL-C, glycaemia, SBP, and DBP was observed. A progressive age-dependent increase in the percentage of patients pharmacologically treated for the cardiometabolic abnormalities was detected in patients with metabolic syndrome, a similar trend being also observed in patients without metabolic syndrome only for the antihypertensives. A clear-cut disproportion between treated versus adequately controlled women (with pharmacotherapy) was detected in the whole population. Conclusions. At least in an Italian context of obese females, the age-dependent worsening of glycaemia and BP exerts a fundamental pathophysiological role in the progressive increase of metabolic syndrome with advancing age, which appears to be not adequately treated in a large part of obese subjects. The results of the present study might be useful for public health decision-makers for programming future more extensive and aggressive non-pharmacological and pharmacological interventions in the obese population.
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- 2021
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31. GAUDI: a preparatory archive for the COROT mission
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Solano, E., Catala, C., Garrido, R., Poretti, E., Janot-Pacheco, E., Gutierrez, R., Gonzalez, R., Mantegazza, L., Neiner, C., Fremat, Y., Charpinet, S., Weiss, W., Amado, P. J., Rainer, M., Tsymbal, V., Lyashko, D., Ballereau, D., Bouret, J. C., Hua, T., Katz, D., Lignieres, F., Luftinger, T., Mittermayer, P., Nesvacil, N., Soubiran, C., Veer-Menneret, C. Van't, Goupil, M. J., Costa, V., Rolland, A., Antonello, E., Bossi, M., Buzzoni, A., Rodrigo, C., Aerts, C., Butler, C. J., Guenther, E., and Hatzes, A.
- Subjects
Astrophysics - Abstract
The GAUDI database (Ground-based Asteroseismology Uniform Database Interface, http://sdc.laeff.esa.es/gaudi/) is a preparatory archive for the COROT (COnvection, ROtation and planetary Transits, http://www.astrsp-mrs.fr/projets/corot/) mission developed at LAEFF (Laboratory for Space Astrophysics and Theoretical Physics, http://www.laeff.esa.es). Its intention is to make the ground-based observations obtained in the preparation of the asteroseismology programme available in a simple and efficient way. It contains spectroscopic and photometric data together with inferred physical parameters for more than 1500 objects gathered since January 1998 in 6 years of observational campaigns. In this paper, the main functionalities and characteristics of the system are described. The observations have been collected at ESO-La Silla, Telescopio Nazionale Galileo, Observatoire de Haute-Provence, South African Astronomical Observatory, Tautenberg Observatory and Sierra Nevada Observatory., Comment: 12 pages, 3 figures (quality degraded). Accepted for publication in The Astronomical Journal
- Published
- 2004
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32. Correction: Rigamonti et al. The Role of Aspartate Transaminase to Platelet Ratio Index (APRI) for the Prediction of Non-Alcoholic Fatty Liver Disease (NAFLD) in Severely Obese Children and Adolescents. Metabolites 2022, 12, 155
- Author
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Antonello E. Rigamonti, Adele Bondesan, Eugenia Rondinelli, Silvano G. Cella, and Alessandro Sartorio
- Subjects
n/a ,Microbiology ,QR1-502 - Abstract
In the original publication [...]
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- 2022
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33. Gender and age related differences in the use of medicines for chronic diseases among undocumented migrants
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Fiorini, Gianfrancesco, Cerri, Cesare, Rigamonti, Antonello E., Bini, Silvia, Marazzi, Nicoletta, Sartorio, Alessandro, and Cella, Silvano G.
- Published
- 2018
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34. The effects of blending on the light curve shape of Cepheids
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Antonello, E.
- Subjects
Astrophysics - Abstract
A short analysis is presented of the effects on the cepheid light curve shape, i.e. on the Fourier parameters usually adopted for its description, of the blending of the stellar image with other close stars. The conclusion is that, within reasonable error, the effects are in general small and the Fourier decomposition is confirmed to be a useful tool for pulsation mode discrimination. A large effect has been found on the phase differences in a narrow period range corresponding to the known resonance centers between pulsation modes., Comment: 5 pages; Research Note submitted to A&A
- Published
- 2002
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35. V39: an unusual object in the field of IC 1613
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Mantegazza, L., Antonello, E., Fugazza, D., Covino, S., and Israel, G.
- Subjects
Astrophysics - Abstract
The variable star V39 in the field of IC 1613 is discussed in the light of the available photometric and new spectroscopic data. It has strong emission Balmer lines, and the observed characteristics could be explained by a W Vir pulsating star with a period of 14.341 d, located at more than 115 kpc, that is in the very outer halo of our Galaxy. It should have an apparent companion, a long period (1118d) red variable, belonging to IC 1613. The main uncertainty in this interpretation is an emission feature at 668.4 nm, which we tentatively identified as a He I line., Comment: 5 pages; accepted for publication in Astronomy & Astrophysics
- Published
- 2002
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36. Variable stars in nearby galaxies. VI. Frequency-period distribution of Cepheids in IC 1613 and other galaxies of the Local Group
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Antonello, E., Fugazza, D., and Mantegazza, L.
- Subjects
Astrophysics - Abstract
The frequency--period distribution and other properties of Cepheids in IC 1613 are discussed and compared with those of stars in our Galaxy (Milky Way), LMC, SMC, M31 and M33. Taking into account the observational limitations and related incompleteness, it is concluded that the frequency-period distribution of Cepheids in IC 1613 is similar to that of SMC; we suspect that a much larger number of stars exist in IC 1613 with a period of less than 2 d that have not yet been detected. A discussion of the deficiency of fundamental mode Cepheids with periods in the range 8 - 10 d in the Milky Way, M31 and M33 is reported. The present data are not sufficient to verify if this is produced by a real bimodal frequency--period distribution or whether depends on the lack of pulsating stars in such a period range due to pulsational stability reasons. Some arguments are presented in favor of a bimodal distribution that is a function of the average metallicity. The Milky Way, M31 and M33 have the two maxima located at the same periods, about 5 and 13 d, respectively. A comment on very long period Cepheids is also given., Comment: 6 pages; accepted for publication in Astronomy and Astrophysics
- Published
- 2002
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37. Variable stars in nearby galaxies. V. Search for Cepheids in Field A of NGC 6822
- Author
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Antonello, E., Fugazza, D., Mantegazza, L., Stefanon, M., and Covino, S.
- Subjects
Astrophysics - Abstract
The results of a CCD survey for variability of stars in the nearby galaxy NGC 6822 are presented. The goal of the survey was to obtain good light curves of Cepheids for Fourier decomposition and to detect shorter period Cepheids. Since the program was carried out with a relatively small telescope, the Dutch 0.9 m at ESO-La Silla, the observations were unfiltered (white light, or Wh-band). The analysis revealed the presence of more than 130 variable stars. 21 population I Cepheids are detected; 6 of them were already known from previous works (Kayser, 1967). For at least three Cepheids, however, the previous identification or period was wrong. Some probable population II (W Vir) stars are also identified. The dispersion of the fundamental mode Cepheid PL relation appears to be small., Comment: 5 pages; accepted for publication in Astronomy and Astrophysics
- Published
- 2002
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38. Undocumented migrants during the Covid-19 pandemic: social conditions, clinical features and pharmacological treatment
- Author
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Gianfrancesco Fiorini, Antonello E. Rigamonti, Charilaos Galanopoulos, Martina Adamoli, Emanuela Ciriaco, Matteo Franchi, Eleonora Genovese, Giovanni Corrao, and Silvano G. Cella
- Subjects
COVID-19 ,undocumented migrants ,chronic diseases ,drugs prescription ,Public aspects of medicine ,RA1-1270 - Abstract
Population groups such as undocumented migrants have been almost completely forgotten during the COVID-19 pandemic, though they have been living in all European countries for decades and new arrivals have continued throughout the pandemic. The aim of this study was to investigate their health conditions during the current pandemic. We analysed the records of 272 patients with respiratory issues attending the outpatient clinic of a large charity in Milan, Italy: amongst them, 18 had COVID-19 confirmed by rhino-pharyngeal swab and 1 of them deceased. All the patients attending the clinic appeared to have several risk factors for COVID-19 and chronic conditions suspected to predispose to the disease and/or to worsen severity and outcomes: hypertension, immunosuppression and previous close contact with COVID-19 patients were the most important ones. Presenting symptoms were worse in patients with COVID-19 than in those with other respiratory issues. These results are discussed in light of the necessity to provide better healthcare to undocumented migrants.
- Published
- 2020
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39. Pre-clinical Research on Bladder Toxicity After Radiotherapy for Pelvic Cancers: State-of-the Art and Challenges
- Author
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Stefania Zuppone, Andrea Bresolin, Antonello E. Spinelli, Giuseppe Fallara, Roberta Lucianò, Federico Scarfò, Fabio Benigni, Nadia Di Muzio, Claudio Fiorino, Alberto Briganti, Andrea Salonia, Francesco Montorsi, Riccardo Vago, and Cesare Cozzarini
- Subjects
small animal ,pre-clinical research ,urinary bladder toxicity ,micro-irradiator ,animal model ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Despite the dramatic advancements in pelvic radiotherapy, urinary toxicity remains a significant side-effect. The assessment of clinico-dosimetric predictors of radiation cystitis (RC) based on clinical data has improved substantially over the last decade; however, a thorough understanding of the physiopathogenetic mechanisms underlying the onset of RC, with its variegated acute and late urinary symptoms, is still largely lacking, and data from pre-clinical research is still limited. The aim of this review is to provide an overview of the main open issues and, ideally, to help investigators in orienting future research. First, anatomy and physiology of bladder, as well as the current knowledge of dose and dose-volume effects in humans, are briefly summarized. Subsequently, pre-clinical radiobiology aspects of RC are discussed. The findings suggest that pre-clinical research on RC in animal models is a lively field of research with growing interest in the development of new radioprotective agents. The availability of new high precision micro-irradiators and the rapid advances in small animal imaging might lead to big improvement into this field. In particular, studies focusing on the definition of dose and fractionation are warranted, especially considering the growing interest in hypo-fractionation and ablative therapies for prostate cancer treatment. Moreover, improvement in radiotherapy plans optimization by selectively reducing radiation dose to more radiosensitive substructures close to the bladder would be of paramount importance. Finally, thanks to new pre-clinical imaging platforms, reliable and reproducible methods to assess the severity of RC in animal models are expected to be developed.
- Published
- 2020
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40. The Role of Aspartate Transaminase to Platelet Ratio Index (APRI) for the Prediction of Non-Alcoholic Fatty Liver Disease (NAFLD) in Severely Obese Children and Adolescents
- Author
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Antonello E. Rigamonti, Adele Bondesan, Eugenia Rondinelli, Silvano G. Cella, and Alessandro Sartorio
- Subjects
aspartate transaminase to platelet ratio index (APRI) ,obesity ,children/adolescents ,biomarker ,non-alcoholic fatty liver disease (NAFLD) ,Microbiology ,QR1-502 - Abstract
The aspartate transaminase to platelet ratio index (APRI) has been proposed as an easy-to-use biochemical marker in obese adults with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatotic hepatitis (NASH). The objective of the present study was to evaluate the clinical and predictive value of APRI in a paediatric obese population. Seven hundred fifty-seven obese children and adolescents (BMI standard deviation score, SDS: >2.0; age range: 10–18.5 years), not consuming alcohol and without hepatitis B or C, were recruited after having been screened for NAFLD by ultrasonography. A series of demographic, biochemical and clinical parameters was compared between the two subgroups (with or without NAFLD); the same parameters were correlated with APRI; and finally, univariable and multivariable logistic regression was used to evaluate the predictors of NAFLD. NAFLD was diagnosed in about 39% of the entire paediatric population, predominantly in males and in subjects suffering from metabolic syndrome. APRI was correlated with the waist circumference (WC), high-density lipoprotein cholesterol (HDL-C), uric acid, total bilirubin, C reactive protein (CRP) and systolic blood pressure (SBP). Furthermore, APRI was higher in males than females, but independent from steatosis severity and metabolic syndrome. With the univariable analysis, the BMI SDS, triglycerides (TG), insulin, homeostatic model assessment for insulin resistance (HOMA-IR), APRI, uric acid and metabolic syndrome were positive predictors of NAFLD, with female sex being negative predictor. At multivariable analysis; however, only BMI SDS, TG, HOMA-IR and APRI were positive predictors of NAFLD, with female sex being a negative predictor. The accuracy of APRI as a biochemical marker of NAFLD was about 60%.In conclusion, in a large (Italian) paediatric obese population, parameters, such as BMI SDS, TG, HOMA-IR and APRI, were positive predictors of NAFLD, with female sex being a negative predictor and most of the prediction explained by APRI. Nevertheless, APRI appears to be a simple biochemical marker of liver injury rather than of NAFLD/NASH and, moreover, is endowed with a limited accuracy for the prediction/diagnosis of NAFLD.
- Published
- 2022
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41. Variable stars in nearby galaxies. II. Population I and II Cepheids in Field A of IC 1613
- Author
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Antonello, E., Mantegazza, L., Fugazza, D., and Bossi, M.
- Subjects
Astrophysics - Abstract
The light curves of Cepheids and other variable stars in Field A of IC 1613, obtained with a CCD and no filter ($Wh$ photometry), have been analyzed. It is possible to separate first overtone from fundamental mode population I Cepheids taking into account the pulsation amplitude, the shape of the light curve and the period. The expected separation is verified in the period--luminosity $PL$ diagram. Light curve Fourier parameters have been compared with those of Magellanic Clouds and galactic Cepheids, in order to point out the effects of the very low metallicity of IC 1613 on the light curve shape. Population II Cepheids of IC 1613 can be discriminated from those of population I in the $PL$ diagram, and, taking into account their color, from other red or blue variables. Their $PL$ relation is consistent with that observed in globular clusters, nearby dwarf spheroidal galaxies and LMC. We have shown it is possible to apply the single-phase method for deriving standard photometry $PL$ relations for population I and II Cepheids; therefore with just one accurate $BVRI$ observation it is possible to use the population I Cepheids for distance determinations. Some unusual stars have been identified on the basis of periods, light curve shapes and colors; they appear to be pulsating stars laying on the extension of $PL$ relation of known anomalous Cepheids. A firmer classification of these and other faint stars requires further deeper multicolor observations., Comment: 9 pages, 11 figures; submitted to Astronomy and Astrophysics
- Published
- 1999
42. Variable stars in nearby galaxies. I. Search for Cepheids in Field A of IC 1613
- Author
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Antonello, E., Mantegazza, L., Fugazza, D., Bossi, M., and Covino, S.
- Subjects
Astrophysics - Abstract
The first results are presented of a four-year program dedicated to the CCD observations of Cepheids in the nearby galaxy IC 1613. Since the program was carried out with a relatively small telescope, the Dutch 0.9 m at ESO-La Silla, the observations were performed without filter (white light), or Wh-band; the advantage of this technique is that the photon statistics correspond to that of V-band observations made with larger telescopes than 2 m and similar exposure time. The effective wavelength of the Wh-band is intermediate between that of V and R bands for stars of A-G spectral type, for back-illuminated CCD detectors. The analysis of the observations of Field A revealed the presence of about 110 variable stars. The detected population I Cepheids are 43; 9 Cepheids were already known from previous works, while most of the new stars have a short period P. For stars with P > 5 d and sufficient phase coverage it is possible to perform good Fourier decomposition of light curves with resulting standard deviation of the fit of 0.02 - 0.04 mag. There are several Cepheids with relatively small amplitude, and most of them are first overtone mode pulsators; the faintest detected Cepheids have V about 23 and P about 1 day. At least 5 population II Cepheids and 8 eclipsing binaries have been observed. The other variable stars are probable long period, semiregular and irregular variables. A comparison with results of other massive CCD photometric projects dedicated to the detection of variable stars shows some advantages of the observations in white light for fully exploiting the capabilities of relatively small telescopes. A suggestion is made on how to use these results for distance determinations., Comment: 17 pages, 15 figures; accepted for publication in Astronomy and Astrophysics
- Published
- 1999
43. X-ray emission from A0-F6 spectral type stars
- Author
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Panzera, M. R., Tagliaferri, G., Pasinetti, L., and Antonello, E.
- Subjects
Astrophysics - Abstract
We use the ROSAT public data archive to study the X-ray emission of a sample of supposedly single A0-F6 spectral type stars from the Bright Star Catalogue. We detected X-ray emission from 19 A and 33 F-type stars. However, our results are not sufficient to associate with certainty the X-ray emission to the A-type stars themselves, since the usual argument that it may originate from a binary companion can not be excluded. A spectral analysis was conducted for 14 sources (3 A and 11 F), finding that for 12 of them a two temperature thermal plasma model is needed to reproduce the observed spectra. The two temperatures are centered at 0.13 and 0.54 keV, respectively. The values found for the higher temperature are lower than that ones of X-ray selected single late-type stars. The X-ray luminosities are in the range 1E28 < L_X < 1E30 erg/s, with a distribution similar to that of active late-type stars. No correlation is found between L_X and B-V color, Vsin(i) and L_bol, while a positive correlation is found between the X-ray luminosity and the hardness ratio., Comment: 11 pages, 2 figures, accepted for publication in A&A
- Published
- 1999
44. Ceramide Risk Score in the Evaluation of Metabolic Syndrome: An Additional or Substitutive Biochemical Marker in the Clinical Practice?
- Author
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Rigamonti, Antonello E., primary, Dei Cas, Michele, additional, Caroli, Diana, additional, Bondesan, Adele, additional, Cella, Silvano G., additional, Paroni, Rita, additional, and Sartorio, Alessandro, additional
- Published
- 2023
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45. Search for second overtone Cepheids in the Magellanic Clouds. I. Study of three candidates in the SMC
- Author
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Mantegazza, L. and Antonello, E.
- Subjects
Astrophysics - Abstract
Accurate CCD observations of three Cepheids in the SMC were made with the purpose of confirming their nature of second overtone mode Cepheids. The stars were suspected pulsating in the second overtone mode owing to the unusual light curve and short period reported by Payne-Gaposchkin & Gaposchkin (1966). The analysis of the new data shows that for two stars the previous periods are wrong, and in the three cases the new light curves are normal. According to the new observations, HV 1353 is a fundamental mode pulsator with small amplitude, and HV 1777 and HV 1779 are first overtone mode pulsators. Also the star HV 1763, whose nature was unknown, was observed in the field of HV 1777. The new data show that it is a first overtone mode Cepheid with P=2.117d., Comment: 6 pages, 8 figures. To be published in A&A Suppl.Ser
- Published
- 1998
46. Search for low instability strip variables in the young open cluster NGC 2516
- Author
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Zerbi, F. M., Mantegazza, L., Campana, S., and Antonello, E.
- Subjects
Astrophysics - Abstract
In this paper we revise and complete the photometric survey of the instability strip of the southern open cluster NGC 2516 published by Antonello and Mantegazza (1986). No variable stars with amplitudes larger than $0^m.02$ were found. However by means of an accurate analysis based on a new statistical method two groups of small amplitude variables have been disentangled: one with periods $< 0^d.25$ (probably $\delta$ Scuti stars) and one with periods $>0^d.025$. The position in the HR diagram and the apparent time-scale may suggest that the stars of the second group belong to a recently discovered new class of variables, named $\gamma$ Dor variables. They certainly deserve further study. We also present a comparison between the results of the photometric survey and the available pointed ROSAT observations of this cluster., Comment: 7 pages, 2 ps figures. Accepted for P.A.S.P
- Published
- 1998
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47. The possible effects of an unusual resonance in very long period Cepheids
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Antonello, E.
- Subjects
Astrophysics - Abstract
The shape of the radial velocity and light curves of 24 long-period (30 < P < 134 days) Cepheids in the Magellanic Clouds shows a progression with the period. The sequences of the radial velocity and light curves are based only on a small sample of stars; however, evident changes of the shape can be seen in Cepheids with period between 90 and 134 d. The Fourier parameter-period diagrams for the radial velocity curves show trends which remind in part those of Cepheids with period near 10 d. The plausible interpretation is a resonance, probably P_0/P_1=2 between the fundamental and the first overtone mode. The possible importance of this phenomenon for the study of stellar structure and evolution in relatively far galaxies is emphasized., Comment: 4 pages, latex, 2 figures, A&A, letter in press
- Published
- 1998
48. A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
- Author
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Spinelli, Antonello E., Bresolin, Andrea, Zuppone, Stefania, Perani, Laura, Fallara, Giuseppe, Di Muzio, Nadia, Vago, Riccardo, Fiorino, Claudio, and Cozzarini, Cesare
- Published
- 2020
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49. Saving, Growth, and Investment: A Macroeconomic Analysis Using a Panel of Countries
- Author
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Attanasio, Orazio P., Picci, Lucio, and Scorcu, Antonello E.
- Published
- 2000
50. Patterns of Gambling Activities and Gambling Problems Among Italian High School Students: Results from a Latent Class Analysis
- Author
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De Luigi, Nicola, Gibertoni, Dino, Randon, Emanuela, and Scorcu, Antonello E.
- Published
- 2018
- Full Text
- View/download PDF
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