Search

Your search keyword '"Antonia Nomayo"' showing total 23 results
Start Over Author "Antonia Nomayo"
23 results on '"Antonia Nomayo"'

2. Safety and Suitability of an Infant Formula Manufactured from Extensively Hydrolysed Protein in Healthy Term Infants

Author

Lindsey Otten, Elisabeth Schelker, Hanna Petersen, Antonia Nomayo, Manja Fleddermann, Bianca M. Arendt, Theresa Britzl, Elisabeth M. Haberl, and Frank Jochum

Subjects
Nutrition and Dietetics, extensively hydrolysed whey protein, protein hydrolysate, infant formula, infant nutrition, infant weight, infant growth, breastfed, neonatal, Food Science
Abstract

We aimed to demonstrate that healthy term infants experience noninferior growth with infant formula manufactured from extensively hydrolysed whey protein (eHF) compared to intact cow’s milk protein (control formula, CF). This prospective, randomised, double-blind, parallel-group, controlled, multicentre trial included healthy term infants who were exclusively formula-fed. Infants ≤ 25 days of age received eHF or CF for at least three months up to 120 days of age, with a follow-up until 180 days of age. A reference group included exclusively breastfed infants (BF). Of 318 infants randomised, 297 (148 CF, 149 eHF) completed the study per protocol. Weight gain up to 120 days of age was noninferior (margin −3.0 g/day) in eHF (28.95 (95% CI: 27.21; 30.68) g/day) compared to CF (28.85 (95% CI: 27.10; 30.61) g/day) with a difference in means of 0.09 g/day and a lower limit of the one-sided 97.5% CI of −0.86 g/day (p < 0.0001 for noninferiority testing). Weight gain remained comparable during follow-up. Further anthropometric parameters did not differ between the infant formula groups throughout the study. Growth was comparable in BF. No relevant safety issues were observed. To conclude, eHF meets infant requirements for adequate growth during the first six months of life and can be considered safe and suitable.

Published
2023
Full Text
View/download PDF

3. Klinische Ernährung und Infusionstherapie

Author

Antonia Nomayo, Carla Aeberhard, Alexandru Ogica, Rainer Dziewas, Elisabeth Schorling, Frank Jochum, Nada Rayes, Hartmut Bertz, Christian Geyer, Eckhard Nagel, Mette M. Berger, Jürgen Piek, Sylvia Weiner, Maike Fedders, Michael Adolph, Mathias Schneeweiß-Gleixner, Zeno Stanga, Hanna Petersen, Mathias Plauth, Alexander Koch, Geraldine de Heer, Peter Stehle, Johann Ockenga, Rainer Wirth, Henryk Pich, Julika Loss, Gunnar Elke, Wolfgang Hartig, Jens Putziger, Georg Lamprecht, Wilfred Druml, Sven Bercker, Christian Trautwein, Bruno Schneeweiß, Thomas Bley, Monika Heilmann, Berthold Koletzko, Kristina Norman, Karl-Heinz Vestweber, Christian Löser, Rudolf Weiner, Bernd-Rüdiger Kern, Hannes-Caspar Petzold, Christian Henker, Matthias Pirlich, Wolfgang Scheppach, Peter Rittler, Gudrun Zürcher, Emilie Reber, Armin Sablotzki, Wolfgang Hartl, Thomas Kremer, Hans Konrad Biesalski, Axel R. Heller, Lindsey Otten, Konstantin Mayer, Georg Kreymann, Stephan C. Bischoff, Arved Weimann, Jann Arends, Roland Radziwill, Michael Hiesmayr, and Ralph Wendt

Published
2021
Full Text
View/download PDF

4. Impact of an Infant Formula Containing a Novel Fat Blend (Cow's Milk Fat, Fish and Vegetable Oil) and Prebiotics on Stool Fatty Acid Soaps and Erythrocyte Fatty Acid Profiles in Full-Term Healthy Newborns

Author

Peter Stehle, Maroula Lambidou, Frank Jochum, Antonia Nomayo, Birgit Alteheld, and Rolf Fimmers

Subjects
Erythrocytes, medicine.medical_treatment, Palmitates, Medicine (miscellaneous), Oligosaccharides, Soaps, Excretion, chemistry.chemical_compound, Animal science, Double-Blind Method, medicine, Glycerol, Animals, Humans, Plant Oils, Feces, Full Term, chemistry.chemical_classification, Nutrition and Dietetics, Milk, Human, business.industry, Prebiotic, Body Weight, Fatty Acids, Infant, Newborn, Fatty acid, Infant, Infant Formula, Milk, Prebiotics, chemistry, Infant formula, Composition (visual arts), Cattle, Female, business
Abstract

Introduction: Recently, new commercial infant formulas have been composed considering novel fat blends and oligosaccharides to better resemble the fatty acid (FA) composition and stereospecific distribution (e.g., increased amount of ß-palmitate) as well as probiotics content of human breast milk. We hypothesized that these newly composed infant formulas may decrease fecal FA soap excretion and may positively affect erythrocyte FA profiles compared with regular formulas. Methods: Healthy infants were randomly assigned to receive a high-sn-2-palmitate formula (>25% of the PA is esterified to the sn-2 position of the glycerol backbone, verum: n = 30) or a “standard” formula containing n = 27); a non-randomized group of breast-fed infants served as control. Anthropometric data of the infants (body weight, recumbent length, and head circumference) were recorded at inclusion (visit 1) and 6 and 12 weeks after onset of intervention (visits 2 and 3). Blood samples for erythrocyte FA analysis (gas chromatography) were taken at visits 1 and 2; stool samples were collected at visit 2. Results: Quantitative formula intake (mL/kg body weight × day) at visit 2 (verum: 155 ± 30, control: 164 ± 30) and visit 3 (verum: 134 ± 26, control: 134 ± 21) was comparable. Six weeks after onset of intervention, stool total FA soaps, palmitate soaps, and total FAs were similar in both formula-fed groups but significantly higher than in breast-fed infants. During the 6-week intervention, erythrocyte palmitate decreased significantly from baseline in all 3 groups with no group differences (verum: 29.20 ± 1.17 to 27.12 ± 0.66, control: 29.88 ± 2.00 to 27.01 ± 0.94, breast-fed: 30.20 ± 0.86 to 26.84 ± 0.98). For selected FAs, significant changes over time in verum and control group were obvious but without formula effects. Some variations in the FA profile of breast-fed infants compared to both verum and control groups were observed. Conclusions: In contrast to our hypothesis, feeding a newly composed infant formula based on a fat blend with 25% of PA in the sn-2 position of triacylglycerols and supplemented with a prebiotic could not decrease insoluble FA soap excretion compared with a standard product; in this respect, breastfeeding is obviously the best choice. Surprisingly, erythrocyte FA profiles were comparable in formula-fed and breast-fed infants; obvious alterations in FA composition of the respective fat sources and structure did not affect FA incorporation into membranes. Caution should be, however, exercised in drawing robust conclusions in the absence of larger, adequately powered intervention studies.

Published
2020

5. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Iron and trace minerals

Author

M. Domellöf, P. Szitanyi, V. Simchowitz, A. Franz, F. Mimouni, Christian Braegger, Jiri Bronsky, Wei Cai, Cristina Campoy, Virgilio Carnielli, Dominique Darmaun, Tamás Decsi, Magnus Domellöf, Nicholas Embleton, Mary Fewtrell, Nataša Fidler Mis, Axel Franz, Olivier Goulet, Corina Hartman, Susan Hill, Iva Hojsak, Silvia Iacobelli, Frank Jochum, Koen Joosten, Sanja Kolaček, Berthold Koletzko, Janusz Ksiazyk, Alexandre Lapillonne, Szimonetta Lohner, Dieter Mesotten, Krisztina Mihályi, Walter A. Mihatsch, Francis Mimouni, Christian Mølgaard, Sissel J. Moltu, Antonia Nomayo, Jean Charles Picaud, Christine Prell, John Puntis, Arieh Riskin, Miguel Saenz De Pipaon, Thibault Senterre, Raanan Shamir, Venetia Simchowitz, Peter Szitanyi, Merit M. Tabbers, Chris H.B. Van Den Akker, Johannes B. Van Goudoever, Anne Van Kempen, Sascha Verbruggen, Jiang Wu, Weihui Yan, Umeå University, Charles University in Prague, Partenaires INRAE, Great Ormond Street Hospital for Children NHS Foundation Trust, University Children's Hospital of Tübingen, Tel Aviv University [Tel Aviv], Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Pediatrics, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, and Neonatology

Subjects
0301 basic medicine, Parenteral Nutrition, medicine.medical_specialty, Iron, iron, trace minerals, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, Metals, Heavy, medicine, Humans, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, 2. Zero hunger, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Infant, Newborn, Infant, Iron and trace minerals, Pediatric parenteral nutrition, Iron Deficiencies, Iron deficiency, medicine.disease, Trace Elements, 3. Good health, Parenteral nutrition, Trace Minerals, Child, Preschool, 030211 gastroenterology & hepatology, Child Nutritional Physiological Phenomena, Deficiency Diseases, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Infant, Premature, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition : Iron and trace minerals

Published
2018
Full Text
View/download PDF

6. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Amino acids

Author

Johannes B. van Goudoever, Virgilio Carnielli, Dominique Darmaun, Miguel Sainz de Pipaon, Christian Braegger, Jiri Bronsky, Wei Cai, Cristina Campoy, Tamás Decsi, Magnus Domellöf, Nicholas Embleton, Mary Fewtrell, Nataša Fidler Mis, Axel Franz, Olivier Goulet, Corina Hartman, Susan Hill, Iva Hojsak, Silvia Iacobelli, Frank Jochum, Koen Joosten, Sanja Kolaček, Berthold Koletzko, Janusz Ksiazyk, Alexandre Lapillonne, Szimonetta Lohner, Dieter Mesotten, Krisztina Mihályi, Walter A. Mihatsch, Francis Mimouni, Christian Mølgaard, Sissel J. Moltu, Antonia Nomayo, Jean Charles Picaud, Christine Prell, John Puntis, Arieh Riskin, Miguel Saenz De Pipaon, Thibault Senterre, Raanan Shamir, Venetia Simchowitz, Peter Szitanyi, Merit M. Tabbers, Chris H.B. Van Den Akker, Johannes B. Van Goudoever, Anne Van Kempen, Sascha Verbruggen, Jiang Wu, Weihui Yan, University of Amsterdam [Amsterdam] (UvA), Salesi Hospital, Partenaires INRAE, Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Universidad Autonoma de Madrid (UAM), Neonatology, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), Pediatrics, and Pediatric surgery

Subjects
0301 basic medicine, Parenteral Nutrition, medicine.medical_specialty, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, medicine, Humans, Amino Acids, requirements, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, 2. Zero hunger, chemistry.chemical_classification, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, pediatric parenteral nutrition, Infant, Newborn, toxicity, Infant, deficiency, 3. Good health, Amino acid, Parenteral nutrition, chemistry, Child, Preschool, Child Nutritional Physiological Phenomena, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Infant, Premature
Abstract

International audience

Published
2018
Full Text
View/download PDF

7. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Venous access

Author

Nicholas D. Embleton, Merit M. Tabbers, Thibault Senterre, Sissel J. Moltu, Christine Prell, Jean Charles Picaud, Olivier Goulet, Peter Szitanyi, Christian Mølgaard, Christian Braegger, Nataša Fidler Mis, Lohner Szimonetta, Anne A.M.W. van Kempen, Dieter Mesotten, Corina Hartman, Chris H. B. van den Akker, Sascha Verbruggen, Jiri Bronsky, Raanan Shamir, Arieh Riskin, Decsi Tamas, Iva Hojsak, I. Hojsak, Francis B. Mimouni, Wu Jiang, Antonia Nomayo, Magnus Domellöf, Koen F. M. Joosten, Walter A. Mihatsch, Mihalyi Krisztina, Janusz Ksiazyk, Miguel Saenz de Pipaon, Virgilio P. Carnielli, Axel R. Franz, Cristina Campoy, Mary Fewtrell, Cai Wei, Yan Weihui, Frank Jochum, Susan Hill, Sanja Kolaček, Venetia Simchowitz, Silvia Iacobelli, Berthold Koletzko, Johannes B. van Goudoever, John W. L. Puntis, Dominique Darmaun, John W L Puntis, Alexandre Lapillonne, Pediatric surgery, Pediatrics, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), University of Zagreb, The General Infirmary at Leeds, Children's Hospital Zagreb, Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, and Neonatology

Subjects
Catheterization, Central Venous, Parenteral Nutrition, medicine.medical_specialty, Central catheter, Topical treatment, Critical Care and Intensive Care Medicine, central venous catheters, central line, central catheter, central venous access, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, medicine, Central Venous Catheters, Humans, Skin hygiene, 030212 general & internal medicine, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, Nutrition and Dietetics, business.industry, Infant, Newborn, Catheter blockage, Infant, Pediatric parenteral nutrition, Catheter-Related Infections, 3. Good health, Venous access, Parenteral nutrition, Child, Preschool, Intravenous nutrition, Child Nutritional Physiological Phenomena, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Infant, Premature, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Venous access

Published
2018
Full Text
View/download PDF

8. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Lipids

Author

Alexandre Lapillonne, Nataša Fidler Mis, Olivier Goulet, Chris H.P. van den Akker, Jennifer Wu, Berthold Koletzko, Christian Braegger, Jiri Bronsky, Wei Cai, Cristina Campoy, Virgilio Carnielli, Dominique Darmaun, Tamás Decsi, Magnus Domellöf, Nicholas Embleton, Mary Fewtrell, Axel Franz, Corina Hartman, Susan Hill, Iva Hojsak, Silvia Iacobelli, Frank Jochum, Koen Joosten, Sanja Kolaček, Janusz Ksiazyk, Szimonetta Lohner, Dieter Mesotten, Krisztina Mihályi, Walter A. Mihatsch, Francis Mimouni, Christian Mølgaard, Sissel J. Moltu, Antonia Nomayo, Jean Charles Picaud, Christine Prell, John Puntis, Arieh Riskin, Miguel Saenz De Pipaon, Thibault Senterre, Raanan Shamir, Venetia Simchowitz, Peter Szitanyi, Merit M. Tabbers, Chris H.B. Van Den Akker, Johannes B. Van Goudoever, Anne Van Kempen, Sascha Verbruggen, Jiang Wu, Weihui Yan, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Baylor College of Medicine (BCM), University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), University of Amsterdam [Amsterdam] (UvA), Shanghai Jiaotong University, University of Munich Medical Center, Partenaires INRAE, Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Pediatrics, Neonatology, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, University of Zurich, Lapillonne, Alexandre, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, and Amsterdam Reproduction & Development (AR&D)

Subjects
0301 basic medicine, Fat Emulsions, Intravenous, Parenteral Nutrition, medicine.medical_specialty, Critical Illness, 610 Medicine & health, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, Cholestasis, parenteral nutrition, lipid/fat emulsions, paediatric, fatty acids, LC-PUFA, IFALD, PNALD, cholestasis, 030225 pediatrics, medicine, Humans, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Poisoning, Infant, Newborn, Infant, medicine.disease, Lipids, 3. Good health, Parenteral nutrition, 10036 Medical Clinic, Child, Preschool, 2916 Nutrition and Dietetics, lipids (amino acids, peptides, and proteins), Child Nutritional Physiological Phenomena, business, 2706 Critical Care and Intensive Care Medicine, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Infant, Premature, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Lipids

Published
2018
Full Text
View/download PDF

9. ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition: Energy

Author

Magnus Domellöf, Miguel Saenz de Pipaon, Koen F. M. Joosten, Johannes B. van Goudoever, Nicholas D. Embleton, Silvia Iacobelli, Berthold Koletzko, Francis B. Mimouni, Arieh Riskin, Wei Cai, Weihui Yan, John W L Puntis, K. Joosten, Jiang Wu, Christian Braegger, Alexandre Lapillonne, Raanan Shamir, Venetia Simchowitz, Sissel J. Moltu, Frank Jochum, Antonia Nomayo, W. Yan, Dieter Mesotten, Anne A.M.W. van Kempen, Olivier Goulet, T. Senterre, Dominique Darmaun, Peter Szitanyi, Virgilio P. Carnielli, Christian Mølgaard, Sascha Bruggen, Sanja Kolaček, N. Embleton, Cristina Campoy, Mary Fewtrell, Susan Hill, Axel R. Franz, Iva Hojsak, Corina Hartman, Merit M. Tabbers, Tamás Decsi, Thibault Senterre, Janusz Ksiazyk, Szimonetta Lohner, Christine Prell, Jean Charles Picaud, Chris H. B. van den Akker, Walter A. Mihatsch, Nataša Fidler Mis, Krisztina Mihalyi, Jiri Bronsky, Sophia Children's Hospital, Newcastle University [Newcastle], Shanghai Jiaotong University, Université de Liège, Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, Pediatrics, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, and Amsterdam Reproduction & Development (AR&D)

Subjects
0301 basic medicine, Parenteral Nutrition, medicine.medical_specialty, Adolescent, Energy metabolism, MEDLINE, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, 030212 general & internal medicine, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, 030109 nutrition & dietetics, Nutrition and Dietetics, Energy, business.industry, Infant, Newborn, Infant, Pediatric parenteral nutrition, Parenteral nutrition, Child, Preschool, Child Nutritional Physiological Phenomena, Energy Metabolism, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Infant, Premature, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Energy

Published
2018
Full Text
View/download PDF

10. ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition: Standard versus individualized parenteral nutrition

Author

Arieh Riskin, Jean-Charles Picaud, Raanan Shamir, Christian Braegger, Jiri Bronsky, Wei Cai, Cristina Campoy, Virgilio Carnielli, Dominique Darmaun, Tamás Decsi, Magnus Domellöf, Nicholas Embleton, Mary Fewtrell, Nataša Fidler Mis, Axel Franz, Olivier Goulet, Corina Hartman, Susan Hill, Iva Hojsak, Silvia Iacobelli, Frank Jochum, Koen Joosten, Sanja Kolaček, Berthold Koletzko, Janusz Ksiazyk, Alexandre Lapillonne, Szimonetta Lohner, Dieter Mesotten, Krisztina Mihályi, Walter A. Mihatsch, Francis Mimouni, Christian Mølgaard, Sissel J. Moltu, Antonia Nomayo, Jean Charles Picaud, Christine Prell, John Puntis, Miguel Saenz De Pipaon, Thibault Senterre, Venetia Simchowitz, Peter Szitanyi, Merit M. Tabbers, Chris H.B. Van Den Akker, Johannes B. Van Goudoever, Anne Van Kempen, Sascha Verbruggen, Jiang Wu, Weihui Yan, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, Technion - Israel Institute of Technology, Hospices Civils de Lyon (HCL), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Tel Aviv University [Tel Aviv], Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Pediatrics, Technion - Israel Institute of Technology [Haifa], Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, and Amsterdam Reproduction & Development (AR&D)

Subjects
0301 basic medicine, Parenteral Nutrition, medicine.medical_specialty, Adolescent, MEDLINE, Critical Care and Intensive Care Medicine, standard parenteral nutrition, individualized parenteral nutrition, individually-tailored or prescribed parenteral nutrition, computerized prescription, premature or preterm infants, very-low-birthweight infants, pediatric patients, infants, children, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Humans, Medicine, Precision Medicine, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, 2. Zero hunger, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Infant, Newborn, Infant, Precision medicine, 3. Good health, Parenteral nutrition, Child, Preschool, Child Nutritional Physiological Phenomena, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition : Standard versus individualized parenteral nutrition

Published
2018
Full Text
View/download PDF

11. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition

Author

Christine Prell, Dominique Darmaun, Walter A. Mihatsch, Anne A.M.W. van Kempen, Venetia Simchowitz, Corina Hartman, Silvia Iacobelli, Krisztina Mihalyi, Berthold Koletzko, Mary Fewtrell, Sanja Kolaček, Arieh Riskin, Antonia Nomayo, Johannes B. van Goudoever, Dieter Mesotten, Nicholas D. Embleton, Virgilio P. Carnielli, Christian Braegger, Francis B. Mimouni, Frank Jochum, Jiri Bronsky, Chris H. B. van den Akker, Sissel J. Moltu, Olivier Goulet, Weihui Yan, Koen F. M. Joosten, Janusz Ksiazyk, John W L Puntis, Jean-Charles Picaud, Szimonetta Lohner, Alexandre Lapillonne, Ranaan Shamir, Tamas Desci, Hill Susan, Cristina Campoy, Merit M. Tabbers, Magnus Domellöf, Miguel Saenz de Pipaon, Jiang Wu, Thibault Senterre, Iva Hojsak, Axel Franz, Peter Szitanyi, Christian Mølgaard, Nataša Fidler Mis, Sascha Verbruggen, Wei Cai, Universität Ulm - Ulm University [Ulm, Allemagne], University Children’s Hospital Zurich, University Hospital Motol [Prague], Shanghai Jiao Tong University [Shanghai], Universidad de Granada = University of Granada (UGR), Polytechnic University of Marche, Université de Nantes (UN), University of Pecs, Umeå University, University of Newcastle upon Tyne, NHS Foundation Trust, University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), University Children's Hospital, Université Paris Descartes - Paris 5 (UPD5), Schneider Children's Medical Center of Israel, Children's Hospital Zagreb, Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), Evangelisches Waldkrankenhaus Spandau, Partenaires INRAE, Eramus MC-Sophia Children’s Hospital, Ludwig-Maximilians University [Munich] (LMU), The Children’s Memorial Health Institute, Katholieke Universiteit Leuven, Department of Pediatrics-Division of Neonatology, University of Alberta, University of Copenhagen = Københavns Universitet (UCPH), Oslo University Hospital [Oslo], Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), The General Infirmary at Leeds, Bnai Zion Medical Center, Hospital Universitario La Paz, Centre Hospitalier Universitaire de Liège (CHU-Liège), General University Hospital in Prague, Emma Children’s Hospital Academic Medical Centre, OLVG Hospital, Xinhua Hospital, ProdInra, Migration, Pediatrics, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), University of Granada, Ludwig Maximilians University of Munich, University of Copenhagen = Københavns Universitet (KU), Paediatric Gastroenterology, AGEM - Digestive immunity, AGEM - Re-generation and cancer of the digestive system, ARD - Amsterdam Reproduction and Development, and Neonatology

Subjects
0301 basic medicine, medicine.medical_specialty, Adolescent, MEDLINE, parenteral nutrition, Clinical nutrition, Critical Care and Intensive Care Medicine, 03 medical and health sciences, [SDV.MHEP.PED] Life Sciences [q-bio]/Human health and pathology/Pediatrics, 0302 clinical medicine, 030225 pediatrics, medicine, Humans, Guideline development, Child, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Infant, Newborn, Consensus conference, Infant, Guideline, Chinese society, Evidence level, 3. Good health, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, Parenteral nutrition, Child, Preschool, Family medicine, Practice Guidelines as Topic, Child Nutritional Physiological Phenomena, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Abstract

International audience; Background: Previous guidelines on Paediatric Parenteral Nutrition (PN) were published in 2010, by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), supported by the European Society of Paediatric Research (ESPR) were published. The aim of the present paper was to provide up-to-date evidence for health professionals working with infants, children and adolescents receiving PN. Methods: The current document is a revision of the 2005 guidelines produced by the same 3 organizations (ESPEN, ESPGHAN, ESPR) together with the Chinese Society of Parenteral and Enteral Nutrition (CSPEN). Experts participating in the guideline updating process were all professionals with extensive experience in managing PN from a wide range of European countries, Israel and China. The guideline development process was coordinated by a guideline steering committee. Each chapter of the guideline was prepared by a separate author group. These author groups were responsible for screening titles and abstracts identified by a systematic literature search for inclusion, for conducting additional expert searches (including secondary sources such as other published valid guidelines), for evaluating the quality of studies included in the given chapter and assigning evidence levels to the literature. Based on the evidence level of included studies experts formulated and graded recommendations. A consensus conference was held in February 2015. All chapter manuscripts were revised following the recommendations of the consensus conference and then reviewed and edited by the project steering committee. Final consensus on each individual guideline and its individual recommendations was achieved and assessed by online voting. This process lasted until January 2018. Funding for the consensus conference (including travel expenses for participants) was provided by all participating societies. No other funding was received for the guideline updating process and participants received no payment. Support was provided by the Hungarian Cochrane organization. Results/conclusions: The present document provides guideline for the use of PN across the wide range of pediatric patients, ranging from extremely premature infants up to teenagers weighing up to and over 100 kg [1]. It covers their individual macro- and micronutrient needs [2], [3], [4], [5], [6], [7], [8], fluid requirements [9], venous access [10], organizational aspects [11], home parenteral nutrition [12], standardized vs. individualized PN [13], and last but not least a wide range of safety considerations for prevention and management of complications such central line associated bloodstream infections (CLABSI)

Published
2018
Full Text
View/download PDF

12. Infant formula with cow's milk fat and prebiotics affects intestinal flora, but not the incidence of infections during infancy in a double-blind randomized controlled trial

Author

Rainer Rossi, Richard Zelenka, Katharina Timme, Antonia Nomayo, Andreas Schwiertz, Josef Tvrdík, Janine Foster, and Frank Jochum

Subjects
0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Pharmaceutical Science, Gut flora, Gastroenterology, Beta-palmitic acid, law.invention, 03 medical and health sciences, fluids and secretions, Randomized controlled trial, Bifidobacteria, law, Standard infant formula, Diabetes mellitus, Internal medicine, medicine, Pharmacology (medical), Feces, 030109 nutrition & dietetics, biology, business.industry, Incidence (epidemiology), Prebiotic, Research, Microbiota, Immunity, medicine.disease, biology.organism_classification, 030104 developmental biology, Complementary and alternative medicine, Infant formula, business, Galactooligosaccharides
Abstract

BackgroundThe postnatal intestinal colonization of human milk-fed and formula-fed infants differs substantially, as does the susceptibility to infectious diseases during infancy. Specific ingredients in human milk, such as prebiotic human milk oligosaccharides and a specifically structured fat composition with high proportion of beta-palmitic acid (beta-PA) promote the growth of intestinal bifidobacteria, which are associated with favorable effects on infants’ health. The present study investigates whether addition of prebiotic galactooligosaccharides (GOS) in combination with higher amounts of beta-PA from cow’s milk fat in infant formula positively affects gut microbiota and the incidence of infections in formula-fed infants.MethodsIn a double-blind controlled trial, formula-fed infants were randomly assigned to either receive an experimental formula containing a higher proportion of beta-PA (20–25%) from natural cow’s milk fat, and a prebiotic supplement (0.5 g GOS/100 ml), or a standard infant formula with low beta-PA (< 10%), without prebiotics. A breast-fed reference group was also enrolled. After 12 weeks, fecal samples were collected to determine the proportion of fecal bifidobacteria. The number of infections during the first year of life was recorded.ResultsAfter 12 weeks, the proportion of fecal bifidobacteria was significantly higher in infants receiving formula with high beta-PA and GOS compared to control, and was similar to the breast-fed group (medians 8.8%, 2.5%, and 5.0% respectively;p< 0.001). The incidence of gastrointestinal or other infections during the first year of life did not differ between groups.ConclusionsThe combination of higher amounts of beta-PA plus GOS increased significantly the proportion of fecal bifidobacteria in formula-fed infants, but did not affect the incidence of infections.Trial registrationThe study protocol was registered with Clinical Trials (Protocol Registration and Results System Trial ID:NCT01603719) on 05/15/2012 (retrospectively registered).

Published
2019

13. Mothers' Consumption of Soy Drink But Not Black Tea Increases the Flavonoid Content of Term Breast Milk: A Pilot Randomized, Controlled Intervention Study

Author

Birgit Alteheld, Peter Stehle, Pamela Meinardus, Antonia Nomayo, Norbert Dahlinger, and Frank Jochum

Subjects
Adult, 0301 basic medicine, Flavonoid, Medicine (miscellaneous), Pilot Projects, Breast milk, Antioxidants, Body Mass Index, law.invention, Young Adult, 03 medical and health sciences, Randomized controlled trial, law, Humans, Ingestion, Medicine, Micronutrients, Food science, Black tea, Flavonoids, chemistry.chemical_classification, Consumption (economics), 030109 nutrition & dietetics, Nutrition and Dietetics, Milk, Human, Tea, business.industry, Body Weight, Polyphenols, food and beverages, Maternal Nutritional Physiological Phenomena, Genistein, Isoflavones, Intervention studies, Diet, Soy Milk, chemistry, Female, business
Abstract

Objective: We performed a pilot RCT to prove the hypothesis that a controlled ingestion of polyphenol-rich beverages (soy drink, decaffeinated black tea) in nutritive dosages by nursing women has an effect on the composition (flavonoid concentration, total antioxidant capacity) of breast milk. Methods: Healthy nursing women were supplemented with either 250 mL of a soy drink (12 mg isoflavones; n = 18), 300 mL decaffeinated black tea (67 mg catechins; n = 18), or 300 mL water (n = 8, control) for 6 days. Milk samples were collected before, during, and after intervention. Flavonoid content (isoflavones/catechins, HPLC) and total antioxidant capacity of milk and test drinks in milk specimens were assessed. Results: Isoflavone content (genistein and daidzein) in breast milk increased up to 12 nmol/L after soy drink consumption; the major flavonoids constituents of black tea (catechin, epicatechin, and respective conjugates) could not be detected in milk samples. With both interventions, the total antioxidant capacity of breast milk was not affected. Conclusions: Mothers' daily consumption of a soy drink considerably increases isoflavone content of breast milk resulting in an estimated daily exposure of 9.6 nmol isoflavones in a 4-month-old suckling infant. Luminal flavanol uptake from black tea consumed by the nursing mother may be too low to affect flavanol concentrations in breast milk.

Published
2017
Full Text
View/download PDF

14. Adequacy and safety of α-lactalbumin–enriched low-protein infant formula: A randomized controlled trial

Author

Janine Foster, Frank Jochum, Josef Tvrdík, Antonia Nomayo, Hanna Petersen, and Richard Zelenka

Subjects
0301 basic medicine, Low protein, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, law.invention, 03 medical and health sciences, 0302 clinical medicine, Animal science, Primary outcome, Randomized controlled trial, law, Diet, Protein-Restricted, Humans, Medicine, Infant Nutritional Physiological Phenomena, Lactalbumin, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Infant, Newborn, Infant, Anthropometry, Infant Formula, Breast Feeding, Infant formula, Female, Dietary Proteins, medicine.symptom, business, Weight gain, Body mass index
Abstract

Objectives The aim of this study was to demonstrate suitability and safety of an infant formula enriched with α-lactalbumin with a reduced protein content of 1.89 g protein/100 kcal. Methods This was a randomized, double-blind controlled trial with 80 healthy newborn infants who were assigned to receive either an isocaloric low- or high-protein content formula (1.89 versus 2.1 g/100 kcal). The low-protein content formula was enriched with α-lactalbumin. A breast-fed reference group of 40 infants was studied concurrently. Anthropometric measures were taken at inclusion, after 6 and 12 wk as well as after 6 and 12 mo of follow-up. Primary outcome was weight gain in g/d between study inclusion to 12 wk. Secondary outcomes included anthropometric measures expressed in Z-scores, mean formula consumption, and caloric intake as well as food tolerance. Results Fifty-two infants in the formula group (low protein: 26, high protein: 26) and 32 in the breast-fed reference group completed the 3-mo intervention period. There was no difference in weight gain among feeding groups at the end of the intervention period. Mean weight gain in g/d was 32 in the low-protein, 31 in the high-protein, and 33 in the breast-fed reference group. No significant difference was found between study groups in Z-scores for weight, length, head circumference, weight-for-length, or body mass index nor for fat percentage at end of intervention and after follow-up. Conclusion α-lactalbumin–enriched formula with a protein content of 1.89 g protein/100 kcal is safe and supports adequate growth.

Published
2020
Full Text
View/download PDF

15. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition:Home parenteral nutrition

Author

Susan Hill, Janusz Ksiazyk, Christine Prell, Merit Tabbers, Christian Braegger, Jiri Bronsky, Wei Cai, Cristina Campoy, Virgilio Carnielli, Dominique Darmaun, Tamás Decsi, Magnus Domellöf, Nicholas Embleton, Mary Fewtrell, Nataša Fidler Mis, Axel Franz, Olivier Goulet, Corina Hartman, Iva Hojsak, Silvia Iacobelli, Frank Jochum, Koen Joosten, Sanja Kolaček, Berthold Koletzko, Alexandre Lapillonne, Szimonetta Lohner, Dieter Mesotten, Krisztina Mihályi, Walter A. Mihatsch, Francis Mimouni, Christian Mølgaard, Sissel J. Moltu, Antonia Nomayo, Jean Charles Picaud, John Puntis, Arieh Riskin, Miguel Saenz De Pipaon, Thibault Senterre, Raanan Shamir, Venetia Simchowitz, Peter Szitanyi, Merit M. Tabbers, Chris H.B. Van Den Akker, Johannes B. Van Goudoever, Anne Van Kempen, Sascha Verbruggen, Jiang Wu, Weihui Yan, University of Zurich, Hill, Susan, Pediatric surgery, Pediatrics, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), NHS Foundation Trust, Institute of Child Health, The Children’s Memorial Health Institute, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), University of Amsterdam [Amsterdam] (UvA), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, and Neonatology

Subjects
Catheter related sepsis, medicine.medical_specialty, Adolescent, 610 Medicine & health, Critical Care and Intensive Care Medicine, home parenteral nutrition, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Intestinal failure, Medicine, Humans, Intensive care medicine, Child, ComputingMilieux_MISCELLANEOUS, 2. Zero hunger, Nutrition and Dietetics, business.industry, pediatric parenteral nutrition, Infant, Newborn, Infant, NUTRITION&DIETETICS, Infant newborn, 3. Good health, Transplantation, Parenteral nutrition, 10036 Medical Clinic, Child, Preschool, 2916 Nutrition and Dietetics, 030211 gastroenterology & hepatology, business, 2706 Critical Care and Intensive Care Medicine, Child Nutritional Physiological Phenomena, Parenteral Nutrition, Home, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition : Home parenteral nutrition

Published
2018
Full Text
View/download PDF

16. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition:Fluid and electrolytes

Author

Szimonetta Lohner, Sissel J. Moltu, Cristina Campoy, Nicholas D. Embleton, S. J. Moltu, Olivier Goulet, Susan Hill, Venetia Simchowitz, Arieh Riskin, Jiang Wu, Peter Szitanyi, Christian Mølgaard, Mary Fewtrell, Nataša Fidler Mis, Iva Hojsak, Corina Hartman, Sascha Verbruggen, A. Nomayo, Antonia Nomayo, Wei Cai, Dominique Darmaun, Yan Weihui, Chris H. B. van den Akker, Francis B. Mimouni, Koen F. M. Joosten, John W L Puntis, F. Jochum, Alexandre Lapillonne, Thibault Senterre, Axel R. Franz, Johannes B. van Goudoever, Walter A. Mihatsch, Virgilio P. Carnielli, S. Iacobelli, T. Senterre, Dieter Mesotten, Frank Jochum, Silvia Iacobelli, Tamás Decsi, Berthold Koletzko, Sanja Kolaček, Christine Prell, Jean Charles Picaud, Krisztina Mihalyi, Merit M. Tabbers, Magnus Domellöf, Miguel Saenz de Pipaon, Anne A.M.W. van Kempen, Christian Braegger, Raanan Shamir, Jiri Bronsky, Janusz Ksiazyk, Oslo University Hospital [Oslo], Université de Liège, Université Paris Descartes - Paris 5 (UPD5), CHU Necker - Enfants Malades [AP-HP], Centre d'Études Périnatales de l'Océan Indien (CEPOI), Université de La Réunion (UR)-Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), CHU Sud Saint Pierre [Ile de la Réunion], Pediatrics, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

Subjects
Parenteral Nutrition, medicine.medical_specialty, [SDV]Life Sciences [q-bio], Water-Electrolyte Imbalance, Critical Care and Intensive Care Medicine, Electrolytes, 03 medical and health sciences, fluid, electrolytes, 0302 clinical medicine, Body Water, 030225 pediatrics, Humans, Medicine, 030212 general & internal medicine, Child, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, Nutrition and Dietetics, Fluid and electrolytes, business.industry, Infant, Newborn, pediatric parenteral nutrition, Infant, 3. Good health, Parenteral nutrition, Child, Preschool, Child Nutritional Physiological Phenomena, business, Infant, Premature
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition : Fluid and electrolytes

Published
2018
Full Text
View/download PDF

17. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Guideline development process for the updated guidelines

Author

S. Lohner, Koen F. M. Joosten, Mary Fewtrell, R. Shamir, Magnus Domellöf, Miguel Saenz de Pipaon, Thibault Senterre, Tamás Decsi, Dieter Mesotten, Jiang Wu, Christine Prell, Jean Charles Picaud, Nicholas D. Embleton, Sanja Kolaček, K. Mihályi, Vlasselaers Dirk, Arieh Riskin, J.B. van Goudoever, Anne A.M.W. van Kempen, Frank Jochum, Jiri Bronsky, Szimonetta Lohner, Sascha Verbruggen, Antonia Nomayo, Virgilio P. Carnielli, Sissel J. Moltu, A. Lapillonne, Olivier Goulet, Weihui Yan, Merit M. Tabbers, Christian Braegger, W. Mihatsch, M. Fewtrell, Krisztina Mihalyi, Silvia Iacobelli, Susan Hill, Janusz Ksiazyk, Raanan Shamir, Berthold Koletzko, Iva Hojsak, Francis B. Mimouni, Johannes B. van Goudoever, John W L Puntis, Alexandre Lapillonne, Walter A. Mihatsch, Venetia Simchowitz, Chris H. B. van den Akker, Dominique Darmaun, Nataša Fidler Mis, Corina Hartman, Axel R. Franz, Wei Cai, Cristina Campoy, Peter Szitanyi, Christian Mølgaard, Paediatrics, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, Universität Ulm - Ulm University [Ulm, Allemagne], Tel Aviv University [Tel Aviv], Vrije Universiteit Amsterdam [Amsterdam] (VU), Institute of Child London (UCL), Moorfields Eye Hospital, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5), University of Pecs, Centre d'Études Périnatales de l'Océan Indien (CEPOI), Université de La Réunion (UR)-Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), CHU Sud Saint Pierre [Ile de la Réunion], Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Reproduction & Development (AR&D), and Pediatrics

Subjects
0301 basic medicine, medicine.medical_specialty, Parenteral Nutrition, Consensus, Adolescent, [SDV]Life Sciences [q-bio], MEDLINE, Clinical nutrition, Online voting, Critical Care and Intensive Care Medicine, 03 medical and health sciences, Paediatric gastroenterology, Medicine, Humans, Guideline development, Child, ComputingMilieux_MISCELLANEOUS, Extremely premature, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, development process, Infant, Newborn, Infant, Pediatric parenteral nutrition, Guideline, 3. Good health, Parenteral nutrition, Family medicine, Child, Preschool, Practice Guidelines as Topic, business, Child Nutritional Physiological Phenomena
Abstract

Background: Previous guidelines on Paediatric Parenteral Nutrition (PN) were published in 2010, by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), supported by the European Society of Paediatric Research (ESPR) were published. The aim of the present paper was to provide up-to-date evidence for health professionals working with infants, children and adolescents receiving PN. Methods: The current document is a revision of the 2005 guidelines produced by the same 3 organizations (ESPEN, ESPGHAN, ESPR) together with the Chinese Society of Parenteral and Enteral Nutrition (CSPEN). Experts participating in the guideline updating process were all professionals with extensive experience in managing PN from a wide range of European countries, Israel and China. The guideline development process was coordinated by a guideline steering committee. Each chapter of the guideline was prepared by a separate author group. These author groups were responsible for screening titles and abstracts identified by a systematic literature search for inclusion, for conducting additional expert searches (including secondary sources such as other published valid guidelines), for evaluating the quality of studies included in the given chapter and assigning evidence levels to the literature. Based on the evidence level of included studies experts formulated and graded recommendations. A consensus conference was held in February 2015. All chapter manuscripts were revised following the recommendations of the consensus conference and then reviewed and edited by the project steering committee. Final consensus on each individual guideline and its individual recommendations was achieved and assessed by online voting. This process lasted until January 2018. Funding for the consensus conference (including travel expenses for participants) was provided by all participating societies. No other funding was received for the guideline updating process and participants received no payment. Support was provided by the Hungarian Cochrane organization. Results/conclusions: The present document provides guideline for the use of PN across the wide range of pediatric patients, ranging from extremely premature infants up to teenagers weighing up to and over 100 kg [1]. It covers their individual macro- and micronutrient needs [2], [3], [4], [5], [6], [7], [8], fluid requirements [9], venous access [10], organizational aspects [11], home parenteral nutrition [12], standardized vs. individualized PN [13], and last but not least a wide range of safety considerations for prevention and management of complications such central line associated bloodstream infections (CLABSI)

Published
2018
Full Text
View/download PDF

18. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Vitamins

Author

Wei Cai, Anne A.M.W. van Kempen, Magnus Domellöf, Riskin Arieh, Alexandre Lapillonne, Sissel J. Moltu, Szimonetta Lohner, Tamás Decsi, Miguel Saenz de Pipaon, Dieter Mesuiten, Jiang Wu, Puntis John, C. Braegger, Yan Weihui, Virgilio P. Carnielli, Christian Braegger, Nicholas D. Embleton, Nataša Fidler Mis, Corina Hartman, Dominique Darmaun, Raanan Shamir, C. Campoy, Sascha Verbruggen, Mary Fewtrell, Sanja Kolaček, Axel Franz, Olivier Goulet, Cristina Campoy, Walter A. Mihatsch, Frank Jochum, Johannes B. van Goudoever, Koen F. M. Joosten, J. Bronsky, Iva Hojsak, Antonia Nomayo, Silvia Iacobelli, Berthold Koletzko, Christine Prell, Jean Charles Picaud, Francis B. Mimouni, Venetia Simchowitz, Merit M. Tabbers, Thibault Senterre, Chris H. B. van den Akker, Susan Hill, Peter Szitanyi, Christian Mølgaard, Janusz Ksiazyk, Krisztina Mihalyi, Jiri Bronsky, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, University Hospital Motol, Partenaires INRAE, Universidad de Granada (UGR), University Children’s Hospital Zurich, Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Pediatrics, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, and Amsterdam Reproduction & Development (AR&D)

Subjects
0301 basic medicine, medicine.medical_specialty, Parenteral Nutrition, Adolescent, Critical Care and Intensive Care Medicine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030225 pediatrics, Medicine, Humans, Intensive care medicine, Child, ComputingMilieux_MISCELLANEOUS, 2. Zero hunger, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, pediatric parenteral nutrition, Infant, Newborn, Infant, Avitaminosis, Vitamins, 3. Good health, Parenteral nutrition, chemistry, Child, Preschool, business, Cholecalciferol, Child Nutritional Physiological Phenomena, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Infant, Premature
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Vitamins

Published
2018
Full Text
View/download PDF

19. ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition: Carbohydrates

Author

Nicholas D. Embleton, Chris H. B. van den Akker, Sanja Kolaček, Merit M. Tabbers, Thibault Senterre, Anne A.M.W. van Kempen, Janusz Ksiazyk, Magnus Domellöf, Jiang Wu, Miguel Saenz de Pipaon, Szimonetta Lohner, Antonia Nomayo, K. Joosten, Sascha Verbruggen, Yan Weihui, Dominique Darmaun, Venetia Simchowitz, Christine Prell, Jean Charles Picaud, Walter A. Mihatsch, Silvia Iacobelli, Berthold Koletzko, A. van Kempen, Dieter Mesotten, Corina Hartman, Wei Cai, Mary Fewtrell, John W L Puntis, Arieh Riskin, Francis B. Mimouni, Axel Franz, Alexandre Lapillonne, Iva Hojsak, Johannes B. van Goudoever, Olivier Goulet, Jiri Bronsky, Koen F. M. Joosten, Susan Hill, Nataša Fidler Mis, Tamás Decsi, Cristina Campoy, Krisztina Mihalyi, D. Mesotten, Frank Jochum, Virgilio P. Carnielli, Sissel J. Moltu, Christian Braegger, Raanan Shamir, S. Verbruggen, Peter Szitanyi, Christian Mølgaard, Université Catholique de Louvain = Catholic University of Louvain (UCL), Sophia Children's Hospital, Onze Lieve Vrouwe Gasthuis (OLVG), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Pediatrics, Pediatric Surgery, ARD - Amsterdam Reproduction and Development, AGEM - Digestive immunity, Paediatric Gastroenterology, AGEM - Re-generation and cancer of the digestive system, Neonatology, Pediatric surgery, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, and Amsterdam Reproduction & Development (AR&D)

Subjects
Blood Glucose, medicine.medical_specialty, Parenteral Nutrition, Critical Illness, Carbohydrates, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Dietary Carbohydrates, Medicine, Humans, 030212 general & internal medicine, Intensive care medicine, Child, ComputingMilieux_MISCELLANEOUS, Glucose Metabolism Disorders, Nutrition and Dietetics, business.industry, Infant, Newborn, Infant, Pediatric parenteral nutrition, 3. Good health, children, parenteral nutrition, glucose, carbohydrate, energy-resource, insulincritical illness, Parenteral nutrition, Child, Preschool, Insulin Resistance, business, Child Nutritional Physiological Phenomena, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Infant, Premature, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Carbohydrates

Published
2018
Full Text
View/download PDF

21. The reactions of parents who think that a child is dying in a seizure--in their own words

Author

Frank M. C. Besag, Antonia Nomayo, and Felicity Pool

Subjects
Adult, Male, Parents, medicine.medical_specialty, Emergency Medical Services, Referral, Adolescent, Impact Seizures, Ambulances, Audit, Behavioral Neuroscience, Epilepsy, Third person, Seizures, Medicine, Outpatient clinic, Humans, Psychiatry, Child, Prolonged seizures, Retrospective Studies, Cyanosis, business.industry, Infant, medicine.disease, Family life, Cardiopulmonary Resuscitation, Death, Hospitalization, Neurology, Child, Preschool, Female, Neurology (clinical), business
Abstract

Purpose The goal of this work was to report the words parents use to describe a seizure in which they thought their child was dying, so as to increase the awareness of professionals with respect to the impact seizures may have on family life. Methods An audit was carried out on 234 cases from a specialist epilepsy center and 35 cases from a tertiary referral outpatient clinic. Results Of the 54 parents who thought their child was dying in a seizure, in 45 cases the parents’ exact words were recorded in the first person, and in 9 cases, their words were reported in the third person. Many parents took actions that illustrated their high degree of concern: 32 children were taken to hospital, 18 by ambulance, and 3 parents gave mouth-to-mouth resuscitation. Conclusions Seizures often cause major concern in parents and many think that their child is dying. Prolonged seizures and limpness and/or cyanosis appear to be associated with this fear. Professionals can gain valuable insight into the impact of seizures on parents by asking them about their reactions to seeing their child having a seizure.

Published
2005

22. Relation between coronary calcium and 10-year risk scores in primary prevention patients

Author

Stephan Achenbach, Axel Schmermund, Thomas J Matarazzo, Antonia Nomayo, Karsten Pohle, Christian Schlundt, T Killip, Georg Couturier, Dieter Ropers, Udo Hoffmann, and Werner G. Daniel

Subjects
Male, medicine.medical_specialty, Correlation coefficient, Coronary Artery Disease, Electron beam tomography, Risk Assessment, Predictive Value of Tests, Risk Factors, Internal medicine, medicine, Humans, Risk factor, Retrospective Studies, Framingham Risk Score, medicine.diagnostic_test, business.industry, Age Factors, Calcinosis, Retrospective cohort study, Middle Aged, medicine.disease, United States, Primary Prevention, Predictive value of tests, Hypertension, Cardiology, Cardiology and Cardiovascular Medicine, business, Risk assessment, Cardiomyopathies, Tomography, X-Ray Computed, Algorithms, Calcification
Abstract

In 380 patients, coronary calcifications were quantified by electron beam tomography and compared with the predicted 10-year cardiovascular event risk determined by the Framingham equation, Adult Treatment Panel III tables, and the PROCAM algorithm. The correlation between the amount of calcium and the predicted cardiac event risk was low (correlation coefficient range 0.19 to 0.28). The assessment of coronary calcium may thus potentially yield information that is additive to the analysis of traditional risk factors.

Published
2003

Catalog

Books, media, physical & digital resources
See catalog results