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1. Association between Vaccination and Persistent Covid-19-Related Symptoms Among Patients with Mild Omicron Infection: A Prospective Cohort Study

Author

Rover, Marciane, primary, Scolari, Fernando Luis, additional, Trott, Geraldine, additional, Dias da Silva, Mariana Motta, additional, de Souza, Denise, additional, dos Santos, Rosa da Rosa Minho, additional, Schardosim, Raíne Fogliati De Carli, additional, de Souza Roldão, Emelyn, additional, Estivalete, Gabriel Pozza, additional, Rech, Gabriela Soares, additional, Mocellin, Duane, additional, de Souza, Jennifer Menna Barreto, additional, Miozzo, Aline Paula, additional, Itaqui, Carolina Rothmann, additional, Nunes da Silva, Gabrielle, additional, de Mesquita Neto, Juliana, additional, Martins Freitas, Hellen Jordan, additional, dos Santos, Catherine Vitória Pereira, additional, Santos da Silveira, Alanys, additional, D'Ávila, Carla Moura, additional, Soares, Christian Morais, additional, Gozzi, João Vítor, additional, dos Santos, Ingrid Flor, additional, Carvalho, Sidiclei Machado, additional, Irineu, Vivian Menezes, additional, Silvestre, Odilson Marques, additional, Borges, Kênia do Carmo Marinho, additional, Neves, Precil Diego Miranda de Menez, additional, Junior, Fernando Azevedo Medrado, additional, Schleder, Juliana Carvalho, additional, dos Santos, Thiago Pelissari, additional, Figueiredo, Estêvão Lanna, additional, Fonseca, Benedito Antonio Lopes da, additional, Zimmermann, Sergio Luiz, additional, Pompilho, Mauricio Antonio, additional, Facchi, Luciane Maria, additional, Gebara, Otavio Celso Eluf, additional, Marcolino, Milena Soriano, additional, Peçanha Antonio, Ana Carolina, additional, Schvartzman, Paulo R., additional, Barreto, Bruna Brandao, additional, Robinson, Caroline Cabral, additional, Falavigna, Maicon, additional, Antonio Nasi, Luiz, additional, Polanczyk, Carisi Anne, additional, Biolo, Andreia, additional, and Rosa, Regis Goulart, additional

Published
2024
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2. Improving door-to-reperfusion time in acute ischemic stroke during the COVID-19 pandemic: experience from a public comprehensive stroke center in Brazil.

Author

Klu, Marcelo, Claudia de Souza, Ana, Augusto Carbonera, Leonardo, Leite Secchi, Thais, Pille, Arthur, Rodrigues, Marcio, Brondani, Rosane, Garcia de Almeida, Andrea, Dal Pizzol, Angélica, Freire Camelo, Daniel Monte, Paulo Mantovani, Gabriel, Oldoni, Carolina, Somma Tessari, Marcelo, Antonio Nasi, Luiz, and Ouriques Martins, Sheila Cristina

Subjects
ISCHEMIC stroke, COVID-19 pandemic, STROKE units, STROKE, STROKE patients, BOLUS radiotherapy, COMPUTED tomography
Abstract

Background: The global COVID-19 pandemic has had a devastating e􀀀ect on global health, resulting in a strain on healthcare services worldwide. The faster a patient with acute ischemic stroke (AIS) receives reperfusion treatment, the greater the odds of a good functional outcome. To maintain the time-dependent processes in acute stroke care, strategies to reorganize infrastructure and optimize human and medical resources were needed. Methods: Data from AIS patients who received thrombolytic therapy were prospectively assessed in the emergency department (ED) of Hospital de Clínicas de Porto Alegre from 2019 to 2021. Treatment times for each stage were measured, and the reasons for a delay in receiving thrombolytic therapy were evaluated. Results: A total of 256 patients received thrombolytic therapy during this period. Patients who arrived by the emergency medical service (EMS) had a lower median door-to-needle time (DNT). In the multivariable analysis, the independent predictors of DNT >60min were previous atrial fibrillation (OR 7) and receiving thrombolysis in the ED (OR 9). The majority of patients had more than one reason for treatment delay. The main reasons were as follows: delay in starting the CT scan, delay in the decision-making process after the CT scan, and delay in reducing blood pressure. Several actions were implemented during the study period. The most important factor that contributed to a decrease in DNT was starting the bolus and continuous infusion of tPA on the CT scan table (decreased the median DNT from 74 to 52, DNT ≤ 60min in 67% of patients treated at radiology service vs. 24% of patients treated in the ED). The DNT decreased from 78min to 66min in 2020 and 57min in 2021 (p = 0.01). Conclusion: Acute stroke care continued to be a priority despite the COVID-19 pandemic. The implementation of a thrombolytic bolus and the start of continuous infusion on the CT scan table was themain factor that contributed to the reduction of DNT. Continuous monitoring of service times is essential for improving the quality of the stroke center and achieving better functional outcomes for patients. [ABSTRACT FROM AUTHOR]

Published
2023
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3. Hospital-Manifested SARS-CoV-2 Infection in Brazil: Clinical Characteristics, Outcomes and Risk Factors for Mortality

Author

Pereira, Polianna Delfino, primary, Pires, Magda Carvalho, additional, Mara Reis Gomes, Virginia, additional, Nogueira, Matheus Carvalho Alves, additional, Lima, Maria Clara Pontello Barbosa, additional, Schwarzbold, Alexandre Vargas, additional, de Oliveira Maurílio, Amanda, additional, Bahia Alves Scotton, Ana Luiza, additional, Soares de Moura Costa, André, additional, Farace, Bárbara Lopes, additional, Castro, Bruno Mateus de, additional, Cimini, Christiane Corrêa Rodrigues, additional, Vitório Silveira, Daniel, additional, Ponce, Daniela, additional, Pereira, Elayne Crestani, additional, Roesch, Eliane Würdig, additional, Manenti, Euler Roberto Fernandes, additional, Cenci, Evelin Paola de Almeida, additional, dos Santos, Fernanda Costa, additional, Anschau, Fernando, additional, Aranha, Fernando Graça, additional, Bartolazzi, Frederico, additional, Nascimento, Guilherme Fagundes, additional, Vianna, Heloisa Reniers, additional, Batista, Joanna, additional, Alvarenga, Joice Coutinho de, additional, Carvalho, Juliana da Silva Nogueira, additional, Machado Rugolo, Juliana, additional, Ruschel, Karen Brasil, additional, da Silva Monteiro, Luanna, additional, Castro, Luis C., additional, Antonio Nasi, Luiz, additional, Floriani, Maiara Anschau, additional, Dias Souza, Maira, additional, Souza-Silva, Maíra Viana Rego, additional, Carneiro, Marcelo, additional, Bicalho, Maria Aparecida Camargos, additional, Frizzo de Godoy, Mariana, additional, Guimarães Júnior, Milton Henriques, additional, Ziegelmann, Patricia K., additional, Ledic Assaf, Pedro, additional, José de Lima Martelli, Petrônio, additional, Finger, Renan Goulart, additional, Francisco, Saionara Cristina, additional, Ferreira Araújo, Silvia, additional, Fischer Oliveira, Talita, additional, Conceição de Oliveira, Thainara, additional, Lage, Thalita Martins, additional, Muller, Vanessa, additional, Carlotto Ramires, Yuri, additional, Ferrari, Teresa Cristina de Abreu, additional, and Marcolino, Milena Soriano, additional

Published
2022
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4. HOSPITAL MORTALITY RATES BETWEEN 2015 AND 2022: A COMPARISON BETWEEN THE PRE-PANDEMIC AND PANDEMIC PERIOD SHOWS THAT COVID-19 IS A CRITICAL HEALTH PROBLEM.

Author

Wolf, Jonas, Petek, Helena, Gasparetto Maccari, Juçara, and Antonio Nasi, Luiz

Subjects
HOSPITAL mortality, DEATH rate, RATINGS of hospitals, COVID-19, PANDEMICS
Abstract

Introduction: COVID-19 caused 6.2 million deaths in the world. The present study aims to evaluate hospital mortality rates from 2015 to 2022, to compare the pre and during the pandemic period. Methods: The study was carried out in a private hospital in southern Brazil. 174,013 hospital discharges between January 2015 and March 2022 were analyzed. Pearson's chi-squared test was performed to evaluate the mortality rate by year. Differences between mortality rates before and during the pandemic was tested with Student's t-test. P-values < 0.05 for all tests were considered significant. Results: Mortality rates were 2.29% in 2015; 2.37% in 2016; 2.25% in 2017; 2.31% in 2018; 2.46% in 2019; 3.45% in 2020; 3.58% in 2021 and 2.77% in 2022 (p < 0.01). The mortality for 2020 and 2021 was higher than in the other years (3.50% ± 0.14 vs 2.34% ± 0.05; p < 0.01). Conclusion: The mortality rates were significantly higher in the years 2020 and 2021, demonstrating that COVID-19 is a critical health problem. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Hospital Characteristics Associated With COVID-19 Mortality: Data From the Multicenter Cohort Brazilian COVID-19 Registry

Author

Souza-Silva, Maíra Viana Rego, primary, Klarmann Ziegelmann, Patrícia, additional, Nobre, Vandack, additional, Mara Reis Gomes, Virginia, additional, da Silva Etges, Ana Paula Beck, additional, Schwarzbold, Alexandre Vargas, additional, Sousa Nunes, Aline Gabrielle, additional, de Oliveira Maurílio, Amanda, additional, Bahia Alves Scotton, Ana Luiza, additional, Soares de Moura Costa, André, additional, Barreto Glaeser, Andressa, additional, Farace, Bárbara Lopes, additional, Ribeiro, Bruno Nunes, additional, Ramos, Carolina Marques, additional, Cimini, Christiane Corrêa Rodrigues, additional, Carvalho, Cíntia Alcantara de, additional, Rempel, Claudete, additional, Vitório Silveira, Daniel, additional, dos Reis Carazai, Daniela, additional, Ponce, Daniela, additional, Pereira, Elayne Crestani, additional, Kroger, Emanuele Marianne Souza, additional, Manenti, Euler Roberto Fernandes, additional, Cenci, Evelin Paola de Almeida, additional, Lucas, Fernanda Barbosa, additional, dos Santos, Fernanda Costa, additional, Anschau, Fernando, additional, Botoni, Fernando Antonio, additional, Aranha, Fernando Graça, additional, de Aguiar, Filipe Carrilho, additional, Bartolazzi, Frederico, additional, Crestani, Gabriela Petry, additional, Vietta, Giovanna Grunewald, additional, Nascimento, Guilherme Fagundes, additional, Noal, Helena Carolina, additional, Duani, Helena, additional, Vianna, Heloisa Reniers, additional, Guimarães, Henrique Cerqueira, additional, Alvarenga, Joice Coutinho de, additional, Chatkin, José Miguel, additional, Drumond Parreiras de Morais, Júlia, additional, Carvalho, Juliana da Silva Nogueira, additional, Machado Rugolo, Juliana, additional, Ruschel, Karen Brasil, additional, de Barros Wanderley Gomes, Lara, additional, Seixas de Oliveira, Leonardo, additional, Barella Zandoná, Liege, additional, Santos Pinheiro, Lilian, additional, Souto Pacheco, Liliane, additional, da Silva Monteiro, Luanna, additional, de Deus Sousa, Lucas, additional, Cesar Souto de Moura, Luis, additional, Elem Almeida Santos, Luisa, additional, Antonio Nasi, Luiz, additional, Alvares de Souza Cabral, Máderson, additional, Floriani, Maiara Anschau, additional, Dias Souza, Maira, additional, Carneiro, Marcelo, additional, Frizzo de Godoy, Mariana, additional, Mastrocolla de Almeida Cardoso, Marilia, additional, Nogueira, Matheus Carvalho Alves, additional, Oscar Soares de Souza Lima, Mauro, additional, Pereira de Figueiredo, Meire, additional, Guimarães Júnior, Milton Henriques, additional, da Cunha Severino Sampaio, Natália, additional, Ramos de Oliveira, Neimy, additional, Guido Soares Andrade, Pedro, additional, Ledic Assaf, Pedro, additional, José de Lima Martelli, Petrônio, additional, Castro Martins, Raphael, additional, Aparecido Valacio, Reginaldo, additional, Pozza, Roberta, additional, Mosmann Menezes, Rochele, additional, Mourato, Rodolfo Lucas Silva, additional, Mendes de Abreu, Roger, additional, de Freitas Silva, Rufino, additional, Francisco, Saionara Cristina, additional, Guimarães, Silvana Mangeon Mereilles, additional, Ferreira Araújo, Silvia, additional, Fischer Oliveira, Talita, additional, Kurtz, Tatiana, additional, Fereguetti, Tatiani Oliveira, additional, Conceição de Oliveira, Thainara, additional, Cristina Neves Marques Barbosa Ribeiro, Yara, additional, Carlotto Ramires, Yuri, additional, Polanczyk, Carísi Anne, additional, and Marcolino, Milena Soriano, additional

Published
2021
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