14 results on '"Appendicitis diagnosis score"'
Search Results
2. Appendicitis
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Poillucci, Gaetano, Podda, Mauro, Gourgiotis, Stavros, Di Saverio, Salomone, Coccolini, Federico, Series Editor, Coimbra, Raul, Series Editor, Kirkpatrick, Andrew W., Series Editor, Di Saverio, Salomone, Series Editor, Ansaloni, Luca, Editorial Board Member, Balogh, Zsolt, Editorial Board Member, Biffl, Walt, Editorial Board Member, Catena, Fausto, Editorial Board Member, Davis, Kimberly, Editorial Board Member, Ferrada, Paula, Editorial Board Member, Fraga, Gustavo, Editorial Board Member, Ivatury, Rao, Editorial Board Member, Kluger, Yoram, Editorial Board Member, Leppaniemi, Ari, Editorial Board Member, Maier, Ron, Editorial Board Member, Moore, Ernest E., Editorial Board Member, Napolitano, Lena, Editorial Board Member, Peitzman, Andrew, Editorial Board Member, Reilly, Patrick, Editorial Board Member, Rizoli, Sandro, Editorial Board Member, Sakakushev, Boris, Editorial Board Member, Sartelli, Massimo, Editorial Board Member, Scalea, Thomas, Editorial Board Member, Spain, David, Editorial Board Member, Stahel, Philip, Editorial Board Member, Sugrue, Michael, Editorial Board Member, Velmahos, George, Editorial Board Member, and Weber, Dieter, Editorial Board Member
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- 2020
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3. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, and Fausto Catena
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Acute appendicitis ,Appendicitis guidelines ,Jerusalem guidelines ,Consensus conference ,Alvarado score ,Appendicitis diagnosis score ,Surgery ,RD1-811 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background and aims Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
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- 2020
- Full Text
- View/download PDF
4. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines.
- Author
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Di Saverio, Salomone, Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Augustin, Goran, Gori, Alice, Boermeester, Marja, Sartelli, Massimo, Coccolini, Federico, Tarasconi, Antonio, de' Angelis, Nicola, Weber, Dieter G., Tolonen, Matti, Birindelli, Arianna, Biffl, Walter, Moore, Ernest E., Kelly, Michael, Soreide, Kjetil, Kashuk, Jeffry, and Ten Broek, Richard
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APPENDICITIS diagnosis , *APPENDICITIS treatment , *INFORMATION storage & retrieval systems , *MEDICAL databases , *MEDICAL information storage & retrieval systems , *MEDICAL protocols , *MEDLINE , *META-analysis , *SYSTEMATIC reviews , *TREATMENT effectiveness , *ACUTE diseases - Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy. [ABSTRACT FROM AUTHOR]
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- 2020
- Full Text
- View/download PDF
5. WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis.
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Di Saverio, Salomone, Birindelli, Arianna, Kelly, Micheal D., Catena, Fausto, Weber, Dieter G., Sartelli, Massimo, Sugrue, Michael, De Moya, Mark, Gomes, Carlos Augusto, Bhangu, Aneel, Agresta, Ferdinando, Moore, Ernest E., Soreide, Kjetil, Griffiths, Ewen, De Castro, Steve, Kashuk, Jeffry, Kluger, Yoram, Leppaniemi, Ari, Ansaloni, Luca, and Andersson, Manne
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APPENDICITIS diagnosis , *CONFERENCES & conventions , *ABDOMINAL pain , *ABSCESSES , *APPENDECTOMY , *CELLULITIS , *CONSENSUS (Social sciences) , *DIAGNOSIS , *DIAGNOSTIC imaging , *MEDICAL errors , *MEDICAL protocols , *PANEL analysis - Abstract
Acute appendicitis (AA) is among the most common cause of acute abdominal pain. Diagnosis of AA is challenging; a variable combination of clinical signs and symptoms has been used together with laboratory findings in several scoring systems proposed for suggesting the probability of AA and the possible subsequent management pathway. The role of imaging in the diagnosis of AA is still debated, with variable use of US, CT and MRI in different settings worldwide. Up to date, comprehensive clinical guidelines for diagnosis and management of AA have never been issued. In July 2015, during the 3rd World Congress of the WSES, held in Jerusalem (Israel), a panel of experts including an Organizational Committee and Scientific Committee and Scientific Secretariat, participated to a Consensus Conference where eight panelists presented a number of statements developed for each of the eight main questions about diagnosis and management of AA. The statements were then voted, eventually modified and finally approved by the participants to The Consensus Conference and lately by the board of co-authors. The current paper is reporting the definitive Guidelines Statements on each of the following topics: 1) Diagnostic efficiency of clinical scoring systems, 2) Role of Imaging, 3) Non-operative treatment for uncomplicated appendicitis, 4) Timing of appendectomy and in-hospital delay, 5) Surgical treatment 6) Scoring systems for intra-operative grading of appendicitis and their clinical usefulness 7) Non-surgical treatment for complicated appendicitis: abscess or phlegmon 8) Pre-operative and post-operative antibiotics. [ABSTRACT FROM AUTHOR]
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- 2016
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6. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Di Saverio, S, Podda, M, De Simone, B, Ceresoli, M, Augustin, G, Gori, A, Boermeester, M, Sartelli, M, Coccolini, F, Tarasconi, A, De' Angelis, N, Weber, D, Tolonen, M, Birindelli, A, Biffl, W, Moore, E, Kelly, M, Soreide, K, Kashuk, J, Ten Broek, R, Gomes, C, Sugrue, M, Davies, R, Damaskos, D, Leppaniemi, A, Kirkpatrick, A, Peitzman, A, Fraga, G, Maier, R, Coimbra, R, Chiarugi, M, Sganga, G, Pisanu, A, De' Angelis, G, Tan, E, Van Goor, H, Pata, F, Di Carlo, I, Chiara, O, Litvin, A, Campanile, F, Sakakushev, B, Tomadze, G, Demetrashvili, Z, Latifi, R, Abu-Zidan, F, Romeo, O, Segovia-Lohse, H, Baiocchi, G, Costa, D, Rizoli, S, Balogh, Z, Bendinelli, C, Scalea, T, Ivatury, R, Velmahos, G, Andersson, R, Kluger, Y, Ansaloni, L, Catena, F, Di Saverio S., Podda M., De Simone B., Ceresoli M., Augustin G., Gori A., Boermeester M., Sartelli M., Coccolini F., Tarasconi A., De' Angelis N., Weber D. G., Tolonen M., Birindelli A., Biffl W., Moore E. E., Kelly M., Soreide K., Kashuk J., Ten Broek R., Gomes C. A., Sugrue M., Davies R. J., Damaskos D., Leppaniemi A., Kirkpatrick A., Peitzman A. B., Fraga G. P., Maier R. V., Coimbra R., Chiarugi M., Sganga G., Pisanu A., De' Angelis G. L., Tan E., Van Goor H., Pata F., Di Carlo I., Chiara O., Litvin A., Campanile F. C., Sakakushev B., Tomadze G., Demetrashvili Z., Latifi R., Abu-Zidan F., Romeo O., Segovia-Lohse H., Baiocchi G., Costa D., Rizoli S., Balogh Z. J., Bendinelli C., Scalea T., Ivatury R., Velmahos G., Andersson R., Kluger Y., Ansaloni L., Catena F., Di Saverio, S, Podda, M, De Simone, B, Ceresoli, M, Augustin, G, Gori, A, Boermeester, M, Sartelli, M, Coccolini, F, Tarasconi, A, De' Angelis, N, Weber, D, Tolonen, M, Birindelli, A, Biffl, W, Moore, E, Kelly, M, Soreide, K, Kashuk, J, Ten Broek, R, Gomes, C, Sugrue, M, Davies, R, Damaskos, D, Leppaniemi, A, Kirkpatrick, A, Peitzman, A, Fraga, G, Maier, R, Coimbra, R, Chiarugi, M, Sganga, G, Pisanu, A, De' Angelis, G, Tan, E, Van Goor, H, Pata, F, Di Carlo, I, Chiara, O, Litvin, A, Campanile, F, Sakakushev, B, Tomadze, G, Demetrashvili, Z, Latifi, R, Abu-Zidan, F, Romeo, O, Segovia-Lohse, H, Baiocchi, G, Costa, D, Rizoli, S, Balogh, Z, Bendinelli, C, Scalea, T, Ivatury, R, Velmahos, G, Andersson, R, Kluger, Y, Ansaloni, L, Catena, F, Di Saverio S., Podda M., De Simone B., Ceresoli M., Augustin G., Gori A., Boermeester M., Sartelli M., Coccolini F., Tarasconi A., De' Angelis N., Weber D. G., Tolonen M., Birindelli A., Biffl W., Moore E. E., Kelly M., Soreide K., Kashuk J., Ten Broek R., Gomes C. A., Sugrue M., Davies R. J., Damaskos D., Leppaniemi A., Kirkpatrick A., Peitzman A. B., Fraga G. P., Maier R. V., Coimbra R., Chiarugi M., Sganga G., Pisanu A., De' Angelis G. L., Tan E., Van Goor H., Pata F., Di Carlo I., Chiara O., Litvin A., Campanile F. C., Sakakushev B., Tomadze G., Demetrashvili Z., Latifi R., Abu-Zidan F., Romeo O., Segovia-Lohse H., Baiocchi G., Costa D., Rizoli S., Balogh Z. J., Bendinelli C., Scalea T., Ivatury R., Velmahos G., Andersson R., Kluger Y., Ansaloni L., and Catena F.
- Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: Use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospi
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- 2020
7. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Di Saverio, S., Podda, M., De Simone, B., Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., De' Angelis, N., Weber, D. G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E. E., Kelly, M., Soreide, K., Kashuk, J., Ten Broek, R., Gomes, C. A., Sugrue, M., Davies, R. J., Damaskos, D., Leppaniemi, A., Kirkpatrick, A., Peitzman, A. B., Fraga, G. P., Maier, R. V., Coimbra, R., Chiarugi, M., Sganga, Gabriele, Pisanu, A., De' Angelis, G. L., Tan, E., Van Goor, H., Pata, F., Di Carlo, I., Chiara, O., Litvin, A., Campanile, F. C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z. J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., Catena, F., Sganga G. (ORCID:0000-0001-5079-0395), Di Saverio, S., Podda, M., De Simone, B., Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., De' Angelis, N., Weber, D. G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E. E., Kelly, M., Soreide, K., Kashuk, J., Ten Broek, R., Gomes, C. A., Sugrue, M., Davies, R. J., Damaskos, D., Leppaniemi, A., Kirkpatrick, A., Peitzman, A. B., Fraga, G. P., Maier, R. V., Coimbra, R., Chiarugi, M., Sganga, Gabriele, Pisanu, A., De' Angelis, G. L., Tan, E., Van Goor, H., Pata, F., Di Carlo, I., Chiara, O., Litvin, A., Campanile, F. C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z. J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L., Catena, F., and Sganga G. (ORCID:0000-0001-5079-0395)
- Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: Use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospi
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- 2020
8. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Fabio Cesare Campanile, Rifat Latifi, Harry van Goor, Francesco Pata, Michael D. Kelly, Mauro Podda, Zaza Demetrashvili, Massimo Sartelli, R. J. Davies, Dimitrios Damaskos, Zsolt J. Balogh, Antonio Tarasconi, Gustavo Pereira Fraga, Fausto Catena, Fakri Abu-Zidan, Sandro Rizoli, Adolfo Pisanu, Ernest E. Moore, Boris Sakakushev, Richard P. G. ten Broek, Osvaldo Chiara, Matti Tolonen, Gian Luigi De' Angelis, Andrey Litvin, Dieter G. Weber, Kjetil Søreide, Andrew W. Kirkpatrick, Rao R. Ivatury, Raul Coimbra, Cino Bendinelli, Michael Sugrue, Oreste Romeo, Luca Ansaloni, Marja A. Boermeester, Goran Augustin, Gabriele Sganga, Ari Leppäniemi, Marco Ceresoli, Ronald V. Maier, Alice Gori, Walter L. Biffl, George C. Velmahos, Arianna Birindelli, Carlos Augusto Gomes, Massimo Chiarugi, Jeffry L. Kashuk, Nicola De Angelis, David W da Costa, Federico Coccolini, Andrew B. Peitzman, Helmut Segovia-Lohse, Salomone Di Saverio, Yoram Kluger, Belinda De Simone, Thomas M. Scalea, Edward C.T.H. Tan, Isidoro Di Carlo, Roland Andersson, Gian Luca Baiocchi, G. Tomadze, Apollo - University of Cambridge Repository, Di Saverio, S, Podda, M, De Simone, B, Ceresoli, M, Augustin, G, Gori, A, Boermeester, M, Sartelli, M, Coccolini, F, Tarasconi, A, De' Angelis, N, Weber, D, Tolonen, M, Birindelli, A, Biffl, W, Moore, E, Kelly, M, Soreide, K, Kashuk, J, Ten Broek, R, Gomes, C, Sugrue, M, Davies, R, Damaskos, D, Leppaniemi, A, Kirkpatrick, A, Peitzman, A, Fraga, G, Maier, R, Coimbra, R, Chiarugi, M, Sganga, G, Pisanu, A, De' Angelis, G, Tan, E, Van Goor, H, Pata, F, Di Carlo, I, Chiara, O, Litvin, A, Campanile, F, Sakakushev, B, Tomadze, G, Demetrashvili, Z, Latifi, R, Abu-Zidan, F, Romeo, O, Segovia-Lohse, H, Baiocchi, G, Costa, D, Rizoli, S, Balogh, Z, Bendinelli, C, Scalea, T, Ivatury, R, Velmahos, G, Andersson, R, Kluger, Y, Ansaloni, L, Catena, F, HUS Abdominal Center, II kirurgian klinikka, University of Helsinki, and Helsinki University Hospital Area
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UNCOMPLICATED ACUTE APPENDICITIS ,CT scan appendicitis ,Appendicitis / surgery ,Settore MED/18 - CHIRURGIA GENERALE ,Non-operative management ,Delphi method ,Review ,030230 surgery ,Imaging ,SUCCESSFUL NONOPERATIVE TREATMENT ,0302 clinical medicine ,Antibiotics ,Laparoscopy / methods ,Appendicitis guideline ,Grading (education) ,Laparoscopy ,Appendicitis diagnosis score ,Appendiceal absce ,Evidence-Based Medicine ,medicine.diagnostic_test ,Consensus conference ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,C-REACTIVE PROTEIN ,3. Good health ,Anti-Bacterial Agents ,Acute appendicitis ,Appendicitis guidelines ,Jerusalem guidelines ,Alvarado score ,Adult Appendicitis Score ,Complicated appendicitis ,Appendectomy ,Laparoscopic appendectomy ,Diagnostic laparoscopy ,Phlegmon ,Appendiceal abscess ,030220 oncology & carcinogenesis ,Abdominal Pain / surgery ,Acute Disease ,Practice Guidelines as Topic ,MEASURING ANATOMIC SEVERITY ,Emergency Medicine ,CT scan appendiciti ,medicine.medical_specialty ,Jerusalem guideline ,lcsh:Surgery ,[object Object] ,Complicated appendiciti ,ANTIBIOTIC-THERAPY ,COMPLICATED ACUTE APPENDICITIS ,03 medical and health sciences ,medicine ,SURGICAL SITE INFECTION ,Humans ,Abdominal Pain / diagnosis ,Anti-Bacterial Agents / therapeutic use ,3-PORT LAPAROSCOPIC APPENDECTOMY ,business.industry ,General surgery ,Kirurgi ,Antibiotic ,Evidence-based medicine ,lcsh:RD1-811 ,lcsh:RC86-88.9 ,3126 Surgery, anesthesiology, intensive care, radiology ,medicine.disease ,Appendicitis ,INFLAMMATORY RESPONSE SCORE ,Abdominal Pain ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,Appendicitis / diagnosis ,CLINICAL-PREDICTION RULES ,Surgery ,Acute appendiciti ,business - Abstract
Background and aims Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
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- 2020
9. მწვავე აპენდიციტის მართვა მოზრდილი ასაკის პაციენტებში, კლინიკური პრაქტიკის ეროვნული რეკომენდაცია (გაიდლაინი)
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მწვავე აპენდიციტი ,არაოპერაციული მართვა ,გაიდლაინი ,Guidelines ,Appendicitis Diagnosis Score ,ლაპაროსკოპული აპენდექტომია ,Consensus Conference ,Laparoscopic Appendectomy ,Non-operative Management ,Alvarado Score ,Acute Appendicitis ,Antibiotics ,Appendectomy ,Complicated Appendicitis ,აპენდექტომია ,ალვარადოს ქულა ,გართულებული აპენდიციტი ,ანტიბიოტიკები - Abstract
მწვავე აპენდიციტი მუცლის მწვავე ტკივილის ერთ-ერთი უხშირესი მიზეზი და გადაუდებელ აბდომინურ ქირურგიაში ოპერაციული ჩარევის ყველაზე ხშირი ჩვენებაა მსოფლიოში. იგი შეიძლება პროგრესირდეს პერფორაციასა და პერიტონიტამდე, რომლებიც ასოცირებულია მძიმე გართულებებთან და სიკვდილობასთან. მწვავე აპენდიციტი გამოირჩევა კლინიკური გამოვლინებებისა და მიმდინარეობის მრავალფეროვნებით, რაც განაპირობებს დიფერენციალური დიაგნოზის სირთულეს. მსოფლიოს მასშტაბით კვლავ საკამათო რჩება გამოსახულებითი კვლევების - ულტრასონოგრაფია, კომპიუტერული ტომოგრაფია, მაგნიტური რეზონანსი - როლი მწვავე აპენდიციტის დიაგნოსტიკაში. მწვავე აპენდიციტის ქირურგიულ მკურნალობაში მოხდა პარადიგმის გადანაცვლება ღია აპენდექტომიიდან ლაპაროსკოპული აპენდექტომიისკენ როგორც მოზრდილებში, ასევე ბავშვებში. ბოლო ათწლეულში, გაურთულებელ შემთხვევებში, ქირურგიული ჩარევის ალტერნატივად მოწოდებულია არაოპერაციული მკურნალობა ანტიბიოტიკებით. მრავალი გაიდლაინის არსებობის მიუხედავად დრემდე არ გამოქვეყნებულა მწვავე აპენდიციტის დიაგნოსტიკისა და მართვის ყოვლისმომცველი კლინიკური რეკომენდაციები. გამონაკლისს არც საქართველო წარმოადგენს. აქედან გამომდინარე, საქართველოს გრიგოლ მუხაძის ქირურგთა ასოციაციამ მიიღო გადაწყვეტილება ჩამოეყალიბებინა ახალი, თანამედროვე საერთაშორისო გაიდლაინებზე დაფუძნებული კლინიკური რეკომენდაციების შედარებით სრულფასოვანი, მოცულობითი გაიდლაინი. ჩვენს მიერ წარმოდგენილი გაიდლაინი ეფუძნება რამდენიმე საერთაშორისო და ქართულ წყაროს. გაიდლაინის შემუშავების პროცესში განხორციელდა სხვადასხვა გაიდლაინების შეჯერება, თარგმნა, შემდგომ ადაპტაცია და ექსპერტიზა დარგის წამყვანი სპეციალისტების მიერ. გაიდლაინის ძირითადი დებულებები განხილული იყო საქართველოს გრიგოლ მუხაძი ქირურგთა ასოციაციის 2018 21 სექტემბრის საერთაშორისო კონგრესზე, რომელიც ჩატარდა გადაუდებელ ქირურგთა მსოფლიო ასოციაციის წარმომადგენლებთან ერთად. ადაპტირების შემდეგ მიღებულ იქნა კონსესუსი საქართველოს ქირურგთა ასოციაციის 2019 წლის სექტემბრის სხდომაზე. ამის გარდა, განხორციელდა გაიდლაინის ძირითადი რეკომენდაციების შედარება და მოდერნიზაცია გადაუდებელი ქირურგიის მსოფლიო საზოგადოების (WSWS) იერუსალიმის გაიდლაინის 2020 წლის განახლებებთან (Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines). წარმოდგენილ ნაშრომში შეჯამებულია რეკომენდაციები და საბაზისო დებულებები შემდეგ საკითხებზე: 1. ქულებით შეფასების ინსტრუმენტების კლინიკური და სადიაგნოსტიკო ეფექტურობა; 2. მწვავე აპენდიციტის ძირითადი სიმპტომები და მათი მნიშვნელობა დიფერენციალურ დიაგნოსტიკაში; 3. გამოსახულებითი კვლევების სენსიტიურობა და სპეციფიკურობა მწვავე აპენდიციტის დიაგნოსტიკაში; 4. გაურთულებელი აპენდიციტის არაოპერაციული მკურნალობა; 5. აპენდექტომიის ვადები და სტაციონარში დაყოვნება; 6. ქირურგიული მკურნალობა; 7. აპენდიციტის ინტრაოპერაციული შეფასება; 8. გართულებული აპენდიციტის მკურნალობა; 9. წინასაოპერაციო და ოპერაციის შემდგომი ანტიბიოტიკოთერაპია; 10. აპენდიციტი განსაკუთრებულ ჯგუფებში: ორსულთა აპენდიციტი, მწვავე აპენდიციტი ბავშვებში, ხანდაზმულებში და იმუნოკომპრომეტირებულ პირებში. გაიდლაინის რეკომენდაციების პრაქტიკაში დანერგვა ხელს შეუწყობს მწვავე აპენდიციტის სწორ და დროულ გამოვლენას, შესაბამისად, დროულ ოპერაციულ მკურნალობას, რაც შეამცირებს არასაჭირო დიაგნოსტიკურ გამოკვლევებთან დაკავშირებულ ხარჯებს, ჩვენების გარეშე წარმოებული აპენდექტომიების რიცხვს და უზრუნველყოფს მკურნალობის შედეგების ოპტიმიზაციას. საკვანძო სიტყვები: მწვავე აპენდიციტი, გაიდლაინი, ალვარადოს ქულა, არაოპერაციული მართვა, ანტიბიოტიკები, გართულებული აპენდიციტი, აპენდექტომია, ლაპაროსკოპული აპენდექტომია, Acute appendicitis is one of the most common reasons of severe abdominal pain and is the most common indication for surgical intervention in emergency abdominal surgery. It can progress to perforation and peritonitis associated with severe complications and death. Acute appendicitis is characterized by a variety of clinical manifestations and course, leading to the difficulty of differential diagnosis. The role of imaging studies (Ultrasound, CT, MRI) in the diagnosis of acute appendicitis remains controversial around the world. In the surgical treatment of acute appendicitis, the paradigm shifted from open appendectomy to laparoscopic appendectomy in both adults and children. In the last decade, in uncomplicated cases, non-surgical treatment with antibiotics has been provided as an alternative to surgical intervention. Despite the existence of many guidelines, comprehensive clinical recommendations for the diagnosis and management of acute appendicitis have not yet been published. Georgia isn't exception. Therefore, the Georgian Association of Surgeons of Grigol Mukhadze has decided to develop a relatively complete, voluminous guideline of clinical recommendations based on new, modern international guidelines. The guideline presented by us is based on several international and Georgian sources. In the process of developing the guideline, various guidelines were agreed upon, translated, further adapted and examined by leading specialists in the field. The main provisions of the guidelines were discussed at the International Congress of Surgeons of Georgia Grigol Mukhadze 2018 on September 21, 2018, which was held together with the representatives of the World Association of Emergency Surgeons. The adaptation was adopted at the September 2019 meeting of the Georgian Surgeons Association. In addition, the main guidelines for guidelines were compared and modernized with the World Emergency Surgery Society (WSWS) with the updated version of the Jerusalem Guideline 2020 (Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines). The present paper summarizes the recommendations and basic provisions on the following issues: 1. Clinical and diagnostic effectiveness of score assessment tools; 2. The main symptoms of acute appendicitis and their importance in differential diagnosis; 3. Sensitivity and specificity of imaging studies in the diagnosis of acute appendicitis; 4. Non-surgical treatment of uncomplicated appendicitis; 5. Deadlines for appendectomy and hospital stay; 6. Surgical treatment; 7. Intraoperative evaluation of appendicitis; 8. Treatment of complicated appendicitis; 9. Preoperative and postoperative antibiotic therapy; 10. Appendicitis in special groups: appendicitis in pregnant women, acute appendicitis in children, the elderly and immunocompromised individuals. The implementation of guideline recommendations in practice will help to identify acute and timely appendicitis, therefore, timely surgical treatment, which will reduce the costs associated with unnecessary diagnostic tests, the number of appendages performed without evidence and provide optimization of treatment outcomes., Guram Tatishvili Bulletin of Georgia Surgery, Выпуск 8 2020, Pages 30-51
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- 2020
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10. WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis
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Michael Sugrue, George C. Velmahos, Ferdinando Agresta, Kurinchi Selvan Gurusamy, Ari Leppäniemi, Walter L. Biffl, Arianna Birindelli, Steve De Castro, Ewen A. Griffiths, Massimo Sartelli, Zsolt J. Balogh, M. D. Kelly, Roberto Persiani, Mark De Moya, Frederick A. Moore, Cino Bendinelli, Gustavo Pereira Fraga, Fausto Catena, Aneel Bhangu, Kjetil Søreide, Fabio Cesare Campanile, Manne Andersson, Luca Ansaloni, Rao R. Ivatury, Jeffry L. Kashuk, Salomone Di Saverio, Elio Jovine, Antonio Biondi, David W da Costa, Carlos Augusto Gomes, Osvaldo Chiara, Sandro Rizoli, Gregorio Tugnoli, Roberto Cirocchi, Ronald V. Maier, Thomas M. Scalea, Dieter G. Weber, Andrew B. Peitzman, Valeria Tonini, Philip F. Stahel, Yoram Kluger, Roland Andersson, Federico Coccolini, Alice Piccinini, Raul Coimbra, Ernest E. Moore, Di Saverio, Salomone, Birindelli, Arianna, Kelly, Micheal D, Catena, Fausto, Weber, Dieter G, Sartelli, Massimo, Sugrue, Michael, De Moya, Mark, Gomes, Carlos Augusto, Bhangu, Aneel, Agresta, Ferdinando, Moore, Ernest E, Soreide, Kjetil, Griffiths, Ewen, De Castro, Steve, Kashuk, Jeffry, Kluger, Yoram, Leppaniemi, Ari, Ansaloni, Luca, Andersson, Manne, Coccolini, Federico, Coimbra, Raul, Gurusamy, Kurinchi S, Campanile, Fabio Cesare, Biffl, Walter, Chiara, Osvaldo, Moore, Fred, Peitzman, Andrew B, Fraga, Gustavo P, Costa, David, Maier, Ronald V, Rizoli, Sandro, Balogh, Zsolt J, Bendinelli, Cino, Cirocchi, Roberto, Tonini, Valeria, Piccinini, Alice, Tugnoli, Gregorio, Jovine, Elio, Persiani, Roberto, Biondi, Antonio, Scalea, Thoma, Stahel, Philip, Ivatury, Rao, Velmahos, George, and Andersson, Roland
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medicine.medical_specialty ,Settore MED/18 - CHIRURGIA GENERALE ,Non-operative management ,MEDLINE ,Review ,Complicated appendiciti ,030230 surgery ,Guidelines ,Guideline ,Acute Appendiciti ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Phlegmon ,Acute Appendicitis, Guidelines, Consensus Conference, Alvarado Score, Appendicitis diagnosis score, Non-operative management, Antibiotics, Complicated appendicitis, Appendectomy, Laparoscopic appendectomy, Phlegmon, Appendiceal abscess ,Randomized controlled trial ,Laparoscopic appendectomy ,law ,Acute Appendicitis ,Antibiotics ,medicine ,Appendectomy ,Abscess ,Appendiceal abscess ,Appendicitis diagnosis score ,Appendiceal absce ,Complicated appendicitis ,business.industry ,General surgery ,Kirurgi ,Antibiotic ,medicine.disease ,Alvarado Score ,Consensus Conference ,Appendicitis ,3. Good health ,Surgery ,Alvarado score ,030220 oncology & carcinogenesis ,Acute appendicitis ,Emergency Medicine ,business - Abstract
Acute appendicitis (AA) is among the most common cause of acute abdominal pain. Diagnosis of AA is challenging; a variable combination of clinical signs and symptoms has been used together with laboratory findings in several scoring systems proposed for suggesting the probability of AA and the possible subsequent management pathway. The role of imaging in the diagnosis of AA is still debated, with variable use of US, CT and MRI in different settings worldwide. Up to date, comprehensive clinical guidelines for diagnosis and management of AA have never been issued. In July 2015, during the 3rd World Congress of the WSES, held in Jerusalem (Israel), a panel of experts including an Organizational Committee and Scientific Committee and Scientific Secretariat, participated to a Consensus Conference where eight panelists presented a number of statements developed for each of the eight main questions about diagnosis and management of AA. The statements were then voted, eventually modified and finally approved by the participants to The Consensus Conference and lately by the board of co-authors. The current paper is reporting the definitive Guidelines Statements on each of the following topics: 1) Diagnostic efficiency of clinical scoring systems, 2) Role of Imaging, 3) Non-operative treatment for uncomplicated appendicitis, 4) Timing of appendectomy and in-hospital delay, 5) Surgical treatment 6) Scoring systems for intra-operative grading of appendicitis and their clinical usefulness 7) Non-surgical treatment for complicated appendicitis: abscess or phlegmon 8) Pre-operative and post-operative antibiotics.
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- 2016
11. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Di Saverio, Salomone, Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Augustin, Goran, Gori, Alice, Boermeester, Marja, Sartelli, Massimo, Coccolini, Federico, Tarasconi, Antonio, De’ Angelis, Nicola, Weber, Dieter G., Tolonen, Matti, Birindelli, Arianna, Biffl, Walter, Moore, Ernest E., Kelly, Michael, Soreide, Kjetil, Kashuk, Jeffry, Ten Broek, Richard, Gomes, Carlos Augusto, Sugrue, Michael, Davies, Richard Justin, Damaskos, Dimitrios, Leppäniemi, Ari, Kirkpatrick, Andrew, Peitzman, Andrew B., Fraga, Gustavo P., Maier, Ronald V., Coimbra, Raul, Chiarugi, Massimo, Sganga, Gabriele, Pisanu, Adolfo, De’ Angelis, Gian Luigi, Tan, Edward, Van Goor, Harry, Pata, Francesco, Di Carlo, Isidoro, Chiara, Osvaldo, Litvin, Andrey, Campanile, Fabio C., Sakakushev, Boris, Tomadze, Gia, Demetrashvili, Zaza, Latifi, Rifat, Abu-Zidan, Fakri, Romeo, Oreste, Segovia-Lohse, Helmut, Baiocchi, Gianluca, Costa, David, Rizoli, Sandro, Balogh, Zsolt J., Bendinelli, Cino, Scalea, Thomas, Ivatury, Rao, Velmahos, George, Andersson, Roland, Kluger, Yoram, Ansaloni, Luca, and Catena, Fausto
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Acute appendicitis ,Complicated appendicitis ,CT scan appendicitis ,Non-operative management ,Review ,Diagnostic laparoscopy ,3. Good health ,Imaging ,Jerusalem guidelines ,Laparoscopic appendectomy ,Antibiotics ,Appendicitis guidelines ,Adult Appendicitis Score ,Alvarado score ,Appendectomy ,Appendicitis diagnosis score ,Appendiceal abscess ,Phlegmon ,Consensus conference - Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
12. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Di Saverio, Salomone, Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Augustin, Goran, Gori, Alice, Boermeester, Marja, Sartelli, Massimo, Coccolini, Federico, Tarasconi, Antonio, De’ Angelis, Nicola, Weber, Dieter G., Tolonen, Matti, Birindelli, Arianna, Biffl, Walter, Moore, Ernest E., Kelly, Michael, Soreide, Kjetil, Kashuk, Jeffry, Ten Broek, Richard, Gomes, Carlos Augusto, Sugrue, Michael, Davies, Richard Justin, Damaskos, Dimitrios, Leppäniemi, Ari, Kirkpatrick, Andrew, Peitzman, Andrew B., Fraga, Gustavo P., Maier, Ronald V., Coimbra, Raul, Chiarugi, Massimo, Sganga, Gabriele, Pisanu, Adolfo, De’ Angelis, Gian Luigi, Tan, Edward, Van Goor, Harry, Pata, Francesco, Di Carlo, Isidoro, Chiara, Osvaldo, Litvin, Andrey, Campanile, Fabio C., Sakakushev, Boris, Tomadze, Gia, Demetrashvili, Zaza, Latifi, Rifat, Abu-Zidan, Fakri, Romeo, Oreste, Segovia-Lohse, Helmut, Baiocchi, Gianluca, Costa, David, Rizoli, Sandro, Balogh, Zsolt J., Bendinelli, Cino, Scalea, Thomas, Ivatury, Rao, Velmahos, George, Andersson, Roland, Kluger, Yoram, Ansaloni, Luca, and Catena, Fausto
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Acute appendicitis ,Complicated appendicitis ,CT scan appendicitis ,Non-operative management ,Review ,Diagnostic laparoscopy ,3. Good health ,Imaging ,Jerusalem guidelines ,Laparoscopic appendectomy ,Antibiotics ,Appendicitis guidelines ,Adult Appendicitis Score ,Alvarado score ,Appendectomy ,Appendicitis diagnosis score ,Appendiceal abscess ,Phlegmon ,Consensus conference - Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
13. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
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Di Saverio, Salomone, Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Augustin, Goran, Gori, Alice, Boermeester, Marja, Sartelli, Massimo, Coccolini, Federico, Tarasconi, Antonio, De’ Angelis, Nicola, Weber, Dieter G., Tolonen, Matti, Birindelli, Arianna, Biffl, Walter, Moore, Ernest E., Kelly, Michael, Soreide, Kjetil, Kashuk, Jeffry, Ten Broek, Richard, Gomes, Carlos Augusto, Sugrue, Michael, Davies, Richard Justin, Damaskos, Dimitrios, Leppäniemi, Ari, Kirkpatrick, Andrew, Peitzman, Andrew B., Fraga, Gustavo P., Maier, Ronald V., Coimbra, Raul, Chiarugi, Massimo, Sganga, Gabriele, Pisanu, Adolfo, De’ Angelis, Gian Luigi, Tan, Edward, Van Goor, Harry, Pata, Francesco, Di Carlo, Isidoro, Chiara, Osvaldo, Litvin, Andrey, Campanile, Fabio C., Sakakushev, Boris, Tomadze, Gia, Demetrashvili, Zaza, Latifi, Rifat, Abu-Zidan, Fakri, Romeo, Oreste, Segovia-Lohse, Helmut, Baiocchi, Gianluca, Costa, David, Rizoli, Sandro, Balogh, Zsolt J., Bendinelli, Cino, Scalea, Thomas, Ivatury, Rao, Velmahos, George, Andersson, Roland, Kluger, Yoram, Ansaloni, Luca, and Catena, Fausto
- Subjects
Acute appendicitis ,Complicated appendicitis ,CT scan appendicitis ,Non-operative management ,Review ,Diagnostic laparoscopy ,3. Good health ,Imaging ,Jerusalem guidelines ,Laparoscopic appendectomy ,Antibiotics ,Appendicitis guidelines ,Adult Appendicitis Score ,Alvarado score ,Appendectomy ,Appendicitis diagnosis score ,Appendiceal abscess ,Phlegmon ,Consensus conference - Abstract
Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
14. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines
- Author
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Di Saverio, Salomone, Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Augustin, Goran, Gori, Alice, Boermeester, Marja, Sartelli, Massimo, Coccolini, Federico, Tarasconi, Antonio, De' Angelis, Nicola, Weber, Dieter G, Tolonen, Matti, Birindelli, Arianna, Biffl, Walter, Moore, Ernest E, Kelly, Michael, Soreide, Kjetil, Kashuk, Jeffry, Ten Broek, Richard, Gomes, Carlos Augusto, Sugrue, Michael, Davies, Richard Justin, Damaskos, Dimitrios, Leppäniemi, Ari, Kirkpatrick, Andrew, Peitzman, Andrew B, Fraga, Gustavo P, Maier, Ronald V, Coimbra, Raul, Chiarugi, Massimo, Sganga, Gabriele, Pisanu, Adolfo, De' Angelis, Gian Luigi, Tan, Edward, Van Goor, Harry, Pata, Francesco, Di Carlo, Isidoro, Chiara, Osvaldo, Litvin, Andrey, Campanile, Fabio C, Sakakushev, Boris, Tomadze, Gia, Demetrashvili, Zaza, Latifi, Rifat, Abu-Zidan, Fakri, Romeo, Oreste, Segovia-Lohse, Helmut, Baiocchi, Gianluca, Costa, David, Rizoli, Sandro, Balogh, Zsolt J, Bendinelli, Cino, Scalea, Thomas, Ivatury, Rao, Velmahos, George, Andersson, Roland, Kluger, Yoram, Ansaloni, Luca, and Catena, Fausto
- Subjects
CT scan appendicitis ,Non-operative management ,Diagnostic laparoscopy ,Imaging ,Laparoscopic appendectomy ,Antibiotics ,Adult Appendicitis Score ,Alvarado score ,Appendectomy ,Humans ,Appendiceal abscess ,Appendicitis diagnosis score ,Acute appendicitis ,Complicated appendicitis ,Evidence-Based Medicine ,Appendicitis ,3. Good health ,Abdominal Pain ,Anti-Bacterial Agents ,Jerusalem guidelines ,Appendicitis guidelines ,Acute Disease ,Practice Guidelines as Topic ,Laparoscopy ,Phlegmon ,Consensus conference - Abstract
BACKGROUND AND AIMS: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. METHODS: This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. CONCLUSIONS: The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.
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