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14. Rapidly Progressive Muscle Weakness

Author

Mehta, Tejas R., Bhatia, Kunal, Arora, Niraj, Arora, Niraj, editor, Govindarajan, Raghav, editor, Kataria, Saurabh, editor, and Nattanmai Chandrasekaran, Premkumar, editor

Published
2020
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23. Blood Pressure after Endovascular Therapy for Ischemic Stroke (BEST): A Multicenter Prospective Cohort Study

Author

Mistry, Eva A., Sucharew, Heidi, Mistry, Akshitkumar M., Mehta, Tapan, Arora, Niraj, Starosciak, Amy K., De Los Rios La Rosa, Felipe, Siegler, James Ernest, III, Barnhill, Natasha R., Patel, Kishan, Assad, Salman, Tarboosh, Amjad, Dakay, Katarina, Salwi, Sanjana, Cruz, Aurora S., Wagner, Jeffrey, Fortuny, Enzo, Bennett, Alicia, James, Robert F., Jagadeesan, Bharathi, Streib, Christopher, O’Phelan, Kristine, Kasner, Scott E., Weber, Stewart A., Chitale, Rohan, Volpi, John J., Mayer, Stephan, Yaghi, Shadi, Jayaraman, Mahesh V., and Khatri, Pooja

Published
2019
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29. Predicting 90-Day Outcome After Thrombectomy: Baseline-Adjusted 24-Hour NIHSS Is More Powerful Than NIHSS Score Change

Author

Mistry, Eva A., primary, Yeatts, Sharon, additional, de Havenon, Adam, additional, Mehta, Tapan, additional, Arora, Niraj, additional, De Los Rios La Rosa, Felipe, additional, Starosciak, Amy K., additional, Siegler, James E., additional, Mistry, Akshitkumar M., additional, Yaghi, Shadi, additional, and Khatri, Pooja, additional

Published
2021
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31. Blood pressure reduction and outcome after endovascular therapy: a secondary analysis of the BEST study

Author

Anadani, Mohammad de Havenon, Adam Yaghi, Shadi Mehta, Tapan and Arora, Niraj Starosciak, Amy Kathryn La Rosa, Felipe De los Rios Siegler, James Mistry, Akshitkumar M. Chitale, Rohan and Spiotta, Alejandro M. Tsivgoulis, Georgios Khatri, Pooja and Mistry, Eva A.

Abstract

Background Elevated systolic blood pressure (SBP) in the acute phase after endovascular therapy (EVT) is associated with worse outcome. However, the association between systolic blood pressure reduction (SBPr) and the outcome of EVT is not well understood. Objective To determine the association between SBPr and clinical outcomes after EVT in a prospective multicenter cohort. Methods A post hoc analysis of the Blood Pressure after Endovascular Stroke Therapy (BEST) prospective observational cohort study was carried out. SBPr was defined as the absolute difference between admission SBP and mean SBP in the first 24 hours after EVT. Logistic regression was used to assess the association between SBPr and poor functional outcome (modified Rankin Scale score 3-6) at 90 days. Results A total of 259/433 (58.5%) patients had poor outcome. SBPr was higher in the poor outcome group than in the good outcome group (26.6 +/- 27.4 vs 19.0 +/- 22.3 mm Hg; p

Published
2021

34. Abstract P502: Significance of Asymptomatic Hemorrhage After Mechanical Thrombectomy: A Post-Hoc Analysis of the Best Study

Author

Feldman, Michael, primary, Roth, Steven, additional, Fusco, Matthew, additional, Yaghi, Shadi, additional, Mehta, Tapan V, additional, Arora, Niraj, additional, Siegler, James E, additional, Schrag, Matthew, additional, Mistry, Akshitkumar M, additional, Chitale, Rohan, additional, Khatri, Pooja, additional, and Mistry, Eva A, additional

Published
2021
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35. Association of asymptomatic hemorrhage after endovascular stroke treatment with outcomes

Author

Feldman, Michael J, primary, Roth, Steven, additional, Fusco, Matthew R, additional, Mehta, Tapan, additional, Arora, Niraj, additional, Siegler, James E, additional, Schrag, Matthew, additional, Mittal, Shilpi, additional, Kirshner, Howard, additional, Mistry, Akshitkumar M., additional, Yaghi, Shadi, additional, Chitale, Rohan V, additional, Khatri, Pooja, additional, and Mistry, Eva A, additional

Published
2021
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36. Blood pressure reduction and outcome after endovascular therapy: a secondary analysis of the BEST study

Author

Anadani, Mohammad, primary, de Havenon, Adam, additional, Yaghi, Shadi, additional, Mehta, Tapan, additional, Arora, Niraj, additional, Starosciak, Amy Kathryn, additional, De Los Rios La Rosa, Felipe, additional, Siegler, James, additional, Mistry, Akshitkumar M, additional, Chitale, Rohan, additional, Spiotta, Alejandro M, additional, Tsivgoulis, Georgios, additional, Khatri, Pooja, additional, and Mistry, Eva A, additional

Published
2020
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39. Pre-endovascular therapy change in blood pressure is associated with outcomes in patients with stroke

Author

Mistry, Eva A, primary, Dakay, Katarina, additional, Petersen, Nils H, additional, Jayaraman, Mahesh, additional, McTaggart, Ryan, additional, Furie, Karen, additional, Mistry, Akshitkumar, additional, Mehta, Tapan, additional, Arora, Niraj, additional, De Los Rios La Rosa, Felipe, additional, Starosciak, Amy Kathryn, additional, Siegler, James E, additional, Barnhill, Natasha, additional, Patel, Kishan, additional, Assad, Salman, additional, Tarboosh, Amjad, additional, Cruz, Aurora Seaton, additional, Wagner, Jeffrey, additional, Fortuny, Enzo, additional, Bennett, Alicia, additional, James, Robert F, additional, Jagadeesan, Bharathi Dasan, additional, Streib, Christopher, additional, Kasner, Scott, additional, Weber, Stuart, additional, Chitale, Rohan V, additional, Volpi, John, additional, Mayer, Stephan A, additional, Khatri, Pooja, additional, and Yaghi, Shadi, additional

Published
2020
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41. Abstract TMP21: Cilostazol for Prevention of Cerebral Vasospasm and Cerebral Ischemia in Patients With Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis of Randomized Controlled Clinical Trials

Author

Lobanova, Iryna, primary, Qualls, Kathryn, additional, Martin, Renee L, additional, Arora, Niraj, additional, Nattanmai, Premkumar, additional, Siddiq, Farhan, additional, French, Brandi R, additional, Gomez, Camilo R, additional, Huang, Wei, additional, and Qureshi, Adnan I, additional

Published
2020
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42. Abstract TMP6: Optimal Early Clinical Endpoints for Long-Term Functional Outcome Prediction After Thrombectomy

Author

Mistry, Eva A, primary, Yeatts, Sharon, additional, Mistry, Akshitkumar, additional, Mehta, Tapan, additional, Arora, Niraj, additional, De Los Rios La Rosa, Felipe, additional, Starosciak, Amy, additional, Siegler, James, additional, Dakay, Katarina, additional, Chitale, Rohan, additional, Yaghi, Shadi, additional, and Khatri, Pooja, additional

Published
2020
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43. Thrombectomy in DAWN- and DEFUSE-3-Ineligible Patients

Author

Siegler, James E, primary, Messé, Steven R, additional, Sucharew, Heidi, additional, Kasner, Scott E, additional, Mehta, Tapan, additional, Arora, Niraj, additional, Starosciak, Amy K, additional, De Los Rios La Rosa, Felipe, additional, Barnhill, Natasha R, additional, Mistry, Akshitkumar M, additional, Patel, Kishan, additional, Assad, Salman, additional, Tarboosh, Amjad, additional, Dakay, Katarina, additional, Salwi, Sanjana, additional, Wagner, Jeff, additional, Bennett, Alicia, additional, Jagadeesan, Bharathi D, additional, Streib, Christopher, additional, Weber, Stewart A, additional, Chitale, Rohan, additional, Volpi, John J, additional, Mayer, Stephan A, additional, Yaghi, Shadi, additional, Jayaraman, Mahesh, additional, Khatri, Pooja, additional, and Mistry, Eva A, additional

Published
2020
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46. Noncontrast CT versus Perfusion‐Based Core Estimation in Large Vessel Occlusion: The Blood Pressure after Endovascular Stroke Therapy Study

Author

Siegler, James E., primary, Messé, Steven R., additional, Sucharew, Heidi, additional, Kasner, Scott E., additional, Mehta, Tapan, additional, Arora, Niraj, additional, Starosciak, Amy K., additional, De Los Rios La Rosa, Felipe, additional, Barnhill, Natasha R, additional, Mistry, Akshitkumar M., additional, Patel, Kishan, additional, Assad, Salman, additional, Tarboosh, Amjad, additional, Dakay, Katarina, additional, Wagner, Jeff, additional, Bennett, Alicia, additional, Jagadeesan, Bharathi, additional, Streib, Christopher, additional, Weber, Stewart A., additional, Chitale, Rohan, additional, Volpi, John J., additional, Mayer, Stephan A., additional, Yaghi, Shadi, additional, Jayaraman, Mahesh V., additional, Khatri, Pooja, additional, and Mistry, Eva A., additional

Published
2019
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47. Native Valve Infective Endocarditis with Osteomyelitis and Brain Abscess Caused by Granulicatella adiacens with Literature Review

Author

Patil, Sachin M., Arora, Niraj, Nilsson, Peter, Yasar, S. J., Dandachi, Dima, and Salzer, W. L.

Subjects
Article Subject
Abstract

Granulicatella adiacens is a type of NVS (nutritionally variant streptococci) rarely causing infective endocarditis (IE). NVS are fastidious and unable to sustain growth on routine culture media due to lack of specific nutrients. Endocarditis caused by NVS due to their virulence is associated with higher treatment failures and mortality rates. New antimicrobial susceptibility patterns are indicative of a significant rise in penicillin resistance and susceptibility differences between NVS subspecies. Initial empirical therapy is essential as a delay in using the appropriate agent leads to poor results. We present a case of an immunocompetent young female with recent intravenous drug abuse resulting in native mitral valve endocarditis with ruptured chordae tendineae and septic embolization, causing brain abscess and lumbar spine osteomyelitis. She was transferred to a tertiary center where she underwent mitral valve replacement successfully and treated with six weeks of intravenous vancomycin and ertapenem. To our knowledge, ours is the first case report of G. adiacens endocarditis in an adult with brain abscess and osteomyelitis with an excellent response to antibiotic therapy. Based on our case report, literature review, and new antimicrobial susceptibility patterns, updates to treatment guidelines are suggested to improve the therapeutic outcomes.

Published
2019
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48. Blood pressure reduction and outcome after endovascular therapy: a secondary analysis of the BEST study.

Author

Anadani, Mohammad, de Havenon, Adam, Yaghi, Shadi, Mehta, Tapan, Arora, Niraj, Starosciak, Amy Kathryn, De Los Rios La Rosa, Felipe, Siegler, James, Mistry, Akshitkumar M., Chitale, Rohan, Spiotta, Alejandro M., Tsivgoulis, Georgios, Khatri, Pooja, and Mistry, Eva A.

Subjects
BLOOD pressure, RESEARCH, STATISTICS, SCIENTIFIC observation, CONFIDENCE intervals, MEDICAL cooperation, TREATMENT effectiveness, DESCRIPTIVE statistics, ENDOVASCULAR surgery, DATA analysis, LOGISTIC regression analysis, SECONDARY analysis, LONGITUDINAL method
Abstract

Background Elevated systolic blood pressure (SBP) in the acute phase after endovascular therapy (EVT) is associated with worse outcome. However, the association between systolic blood pressure reduction (SBPr) and the outcome of EVT is not well understood. Objective To determine the association between SBPr and clinical outcomes after EVT in a prospective multicenter cohort. Methods A post hoc analysis of the Blood Pressure after Endovascular Stroke Therapy (BEST) prospective observational cohort study was carried out. SBPr was defined as the absolute difference between admission SBP and mean SBP in the first 24 hours after EVT. Logistic regression was used to assess the association between SBPr and poor functional outcome (modified Rankin Scale score 3-6) at 90 days. Results A total of 259/433 (58.5%) patients had poor outcome. SBPr was higher in the poor outcome group than in the good outcome group (26.6±27.4 vs 19.0±22.3 mm Hg; p<0.001). However, in adjusted models, SBPr was not independently associated with poor outcome (OR=1.00 per 1 mm Hg increase, 95% CI 0.99 to 1.01) or death (OR=0.9 per 1 mm Hg increase; 95% CI 0.98 to 1.00). No association remained when SBPr was divided into tertiles. Subgroup analyses based on history of hypertension, revascularization status, and antihypertensive treatment yielded similar results. Conclusion The reduction in baseline SBP following EVT was not associated with poor functional outcomes. Most of the cohort (88%) achieved successful recanalization, and therefore, these results mainly apply to patients with successful recanalization. [ABSTRACT FROM AUTHOR]

Published
2021
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