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330 results on '"Arshad, Muhammad Imran"'

25. Multifunctional Ce+3 doped nickel-cobalt mixed ferrites via co-precipitation method for photocatalytic and antibacterial activity

Author

Akram, Muhammad, primary, Junaid, Abdul Hafeez, additional, Ishaque, Muhammad Zahid, additional, Zaman, Yasir, additional, Shahzad, Muhammad, additional, Siddique, Abu Bakar, additional, Kanwal, Humaira, additional, Anis ur Rehman, Muhammad, additional, Arshad, Muhammad Imran, additional, and Ali, Daoud, additional

Published
2024
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30. Transport Properties of Ce-Doped Cd Ferrites CdFe2−xCexO4

Author

Amin, Nasir, Razaq, Abdul, Rehman, Atta Ur, Hussain, Khalid, Nabi, M. Ajaz Un, Morley, N. A., Amami, Mongi, Bibi, Aisha, Arshad, Muhammad Imran, Mahmood, Khalid, Fatima, Muneeba, Akhtar, Maria, Akbar, Sofia, Manzoor, Alina, Ali, Hafiz T., Yusuf, Mohammad, and Amin, Sana

Published
2021
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32. Phage-antibiotic synergism against Salmonella typhi isolated from stool samples of typhoid patients.

Author

Ali, Saqib, Aslam, Muhammad Aamir, Kanwar, Rabia, Mehmood, Zain, Arshad, Muhammad Imran, and Hussain, Sarfaraz

Abstract

Background: Typhoid fever is a fatal disease in humans that is caused by Salmonella typhi. S. typhi infections need immediate antibiotic therapy, and their extensive use has led to multidrug-resistant (MDR) pathogens. The use of bacteriophages is becoming a new way to treat these resistant bacteria. This research was directed to bacteriophage isolation against S. typhi and to determine phage-antibiotic synergism. Aims: To isolate bacteriophages targeting S. typhi, the causative agent of typhoid fever, and investigate their potential synergistic effects when combined with antibiotics. Study design: A cross-sectional study. Methods: The Widal test was positive; twenty diarrheal stool samples were taken, and for confirmation of S. typhi, different biochemical tests were performed. The disc-diffusion technique was used to determine antimicrobial resistance, and the double agar overlay method was used for bacteriophage isolation from sewage water against S. typhi. To test antibiotic-phage synergism, the S. typhi bacteria was treated by phages together with varying antibiotic concentrations. Results: Eleven samples were positive for S. typhi with black colonies on SS-agar. These were catalase and MR positive with alkali butt on TSI. Clear plaques were observed after the agar overlay. Isolated phages were stable at various pH and temperature levels. Synergism was observed on agar plate. The zone was enlarged when phages were combined with bacterial lawn culture and ciprofloxacin disk. Bacterial growth inhibition had a significant p-value of 0.03 in titration plates, with the phage-ciprofloxacin combination being more effective than the phage and antibiotic alone. Conclusion: The study highlights the synergistic effects of isolated bacteriophages with antibiotics, which are not only effective against S. typhi infection but also decrease antibiotic resistance. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Exploring the biogenic peptide's potential in combating bacterial zoonosis: application and future prospect – a review.

Author

Tahir, Saleha, Abbas, Rao Zahid, Qamar, Warda, Arshad, Muhammad Imran, Alvi, Mughees Aizaz, Mahmood, Muhammad Shahid, and Zaheer, Tean

Subjects
PEPTIDES, ZOONOSES, ANTIMICROBIAL peptides, COMMUNICABLE diseases, PUBLIC health
Abstract

Worldwide, microbial infections have a serious impact because they cause infectious diseases, death, and significant economic losses. Zoonosis is now a major public health issue on a global scale because of the fast expansion of human exploitation of nature and animal husbandry. Notably, in the past 30 years, over 30 novel human infections have been discovered, 75% of which fall under the category of zoonosis. Resistant strains have emerged as a result of improper use of antibiotics and insufficient infection management posing a serious risk to both public health and the global economy. As alternatives, antimicrobial peptides are showing good results. The majority of living things use antibacterial peptides (ABPs) as a key part of their natural defenses against invading infections. These peptides are cationic, amphipathic, and relatively tiny with varied sequences, structures, and lengths. For the delivery of these efficacious biological peptides, nanoparticles are providing opportunities for effective, safe, and viable delivery. An innovative method of treating infectious diseases is demonstrated by nanoparticles and antibacterial peptides. When ABPs are combined with carrier nanoparticles to optimize distribution, their half-life may be increased, allowing for lower dosages and ultimately lower toxicity. For biological applications, ABPs and nanoparticle conjugates have become effective methods, enabling the treatment, prevention of disease, and detection. More than 50 peptide medications have been made available for purchase on the market as of 2018. Around 25 billion USD is spent on peptide medications each year, including ABPs. But still, there is a gap in the distribution of these ABPs as an alternative to synthetic antibiotics. It might be due to the high cost of these goods. Thus, scientists, researchers, and commercializing companies should work together so that these ABPs with a safe delivery system should be available in the market to combat resistant strains of bacteria. In doing so, we draw attention to the significant advancements made in the field as well as the difficulties still encountered in developing imaging species, active therapies, and nano-drug delivery systems that are functionalized with peptides and proteins for clinical use. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Novel insights regarding the safety and efficacy of pyrethroid-coated nanoparticles against Hyalomma ticks.

Author

Zaheer, Tean, Abbas, Rao Zahid, Rehman, Tauseef Ur, Khan, Muhammad Kasib, and Arshad, Muhammad Imran

Subjects
IRON oxide nanoparticles, HYALOMMA, IXODIDAE, TICKS, PYRETHROIDS, NANOPARTICLES
Abstract

Nanoparticles have been shown to inhibit major life cycle stages of ticks, indicative of the promising application of nanomaterials against hard ticks. The study thus probed into one of the alternative options to curtail Hyalomma by employing nanocomposites consisting of pyrethroids (cypermethrin and deltamethrin) coated nanoparticles of iron oxides and iron sulfides keeping alongside the evaluation of their toxicity through plant and mammalian cell lines. The nanoparticles used in this study were roughly spherical in morphology and exhibited various size dimensions upon characterization using SEM, EDX, and FTIR. The application of nanomaterials on female ovipositioning tick showed a decline up to 15% (females ovipositioned) in deltamethrin-coated FeO NPs, whereas this decline was up to 18% in Cyp-FeS NPs and up to 5% in Cyp-FeO NPs. Similarly, the larval hatching was also impacted, leading to a hatching percentage of 5% and only 1% by application of Cyp-FeS NPs and Cyp-FeO NPs, respectively. Similarly, the larval groups had LC90 of 4.1 and 4.73 mg/L for the Cyp-FeO NPs and Cyp-FeS NPs groups. The delta-FeO NPs and delta-FeS NPs demonstrated a promising effect against adult ticks, showing LC50= 3.5 mg/L, LC90= 6.7 mg/L and LC50= 3.8 mg/L, LC90= 7.9 mg/L, respectively. MTT assay revealed that the pyrethroids coupled with iron oxide nanoparticles showed the least cytotoxicity even at the highest concentration (10–1 µL) among other nanomaterials. The study thus concluded a safer spectrum of non-target effects of pyrethroids-coated nanomaterials in addition to their significant anti-tick activity. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Corrigendum: Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants

Author

Zeeshan, Muhammad Abid, primary, Ali, Sarmad, additional, Ahmed, Ishtiaq, additional, Rehman, Aziz ur, additional, Rafique, Muhammad Kamran, additional, Nasir, Amar, additional, Khan, Aman Ullah, additional, Kashif, Muhammad, additional, Mertens-Scholz, Katja, additional, Arshad, Muhammad Imran, additional, Ehtisham-ul-Haque, Syed, additional, and Neubauer, Heinrich, additional

Published
2023
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47. Improving the structural and transport properties of cadmium ferrites with the addition of cerium for high frequency applications

Author

Akram, Muhammad, primary, Rehman, Atta Ur, additional, Amin, Nasir, additional, Akhlaq, Saman, additional, Ifseisi, Ahmad A., additional, Akhtar, Maria, additional, Tung, Le Duc, additional, Thanh, Nguyen Thi Kim, additional, Morley, Nicola, additional, Sadiq, Sania, additional, Hussain, Safdar, additional, Ishaque, Muhammad Zahid, additional, Zaman, Yasir, additional, and Arshad, Muhammad Imran, additional

Published
2023
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48. Carbapenem Resistance: Mechanisms and Drivers of Global Menace

Author

Aslam, Bilal, primary, Rasool, Maria, additional, Muzammil, Saima, additional, Baker Siddique, Abu, additional, Nawaz, Zeeshan, additional, Shafique, Muhammad, additional, Asif Zahoor, Muhammad, additional, Binyamin, Rana, additional, Waseem, Muhammad, additional, Khurshid, Mohsin, additional, Arshad, Muhammad Imran, additional, Aamir Aslam, Muhammad, additional, Shahzad, Naveed, additional, Hidayat Rasool, Muhammad, additional, and Baloch, Zulqarnain, additional

Published
2020
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