29 results on '"Arslan HH"'
Search Results
2. Effects of hyperbaric oxygen and dexamethasone on proinflammatory cytokines of rat cochlea in noise-induced hearing loss.
- Author
-
Arslan HH, Satar B, Serdar MA, Ozler M, and Yilmaz E
- Published
- 2012
- Full Text
- View/download PDF
3. Monitoring of environmental persistent organic pollutants in hair samples of cats and dogs.
- Author
-
Yavuz O, Arslan HH, Tokur O, Marangoz O, Nuhoglu Ozturk Z, and Mushtaq S
- Subjects
- Animals, Dogs, Cats, Male, Female, Pesticides analysis, Turkey, Polycyclic Aromatic Hydrocarbons analysis, Gas Chromatography-Mass Spectrometry, Hydrocarbons, Chlorinated analysis, Environmental Pollutants analysis, Hair chemistry, Environmental Monitoring methods, Polychlorinated Biphenyls analysis, Persistent Organic Pollutants
- Abstract
This study investigated 32 persistent organic pollutants, including 9 organochlorine pesticides, 15 polychlorinated biphenyls, 6 polycyclic aromatic hydrocarbons, and 2 organophosphate pesticides in the hair samples of domestic cats and dogs living in an urban area in Samsun, Turkiye. Hair samples were collected from 35 cats and 38 dogs, grouped by sex and age (<3 or >3 years old). Samples were extracted using a liquid-liquid extraction method and analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results revealed the presence of organochlorine pesticides (n = 58, 468.65 ± 92.30 ng/g), polycyclic aromatic hydrocarbons (n = 57, 15.65 ± 3.91 ng/g), polychlorinated biphenyls (n = 55, 54.11 ± 9.47 ng/g), and organophosphate pesticides (n = 25, 568.43 ± 113.17 ng/g) in the samples. PCBs 81, 118, 128, 208, and 2,4-DDE were not detected in any samples. Only one sample did not contain any of the searched compounds. Fluorene was the most frequently detected pollutant (n = 53, 72.6 %), followed by β-hexachlorocyclohexane (n = 34, 46.6 %). The highest maximum concentration was observed for hexachlorobenzene (2748.03 ng/g), followed by aldrin (2313.45 ng/g) and fenitrothion (2081.13 ng/g). Pollutant concentrations did not differ between cats and dogs, sexes, and ages (p > 0.05). This study highlights the significant threat that urban areas pose to pets, and therefore, POPs should be monitored periodically in hair and other samples. To the best of our knowledge, this is the first report to investigate POP levels in hair samples from cats and dogs in Turkiye., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
4. Phenotypic and Genotypic Characterization of Veterinary Vibrio cincinnatiensis Isolates.
- Author
-
Jäckel C, Hammerl JA, Arslan HH, Göllner C, Vom Ort N, Taureck K, and Strauch E
- Abstract
Vibrio cincinnatiensis is a halophilic species which has been found in marine and estuarine environments worldwide. The species is considered a rare pathogen for which the significance for humans is unclear. In this study, nine veterinary isolates were investigated that were obtained from domestic animals in Germany. The isolates were mostly recovered from abortion material of pigs, cattle, and horse (amnion or fetuses). One isolate was from a goose. A human clinical strain from a case of enteritis in Germany described in the literature was also included in the study. Whole-genome sequencing (WGS) of all isolates and MALDI-TOF MS (matrix-assisted-laser-desorption/ionization time-of-flight mass spectrometry) were performed to verify the species assignment. All strains were investigated for phenotypic traits including antimicrobial resistance (AMR), biochemical properties, and two virulence-associated phenotypes (hemolytic activity and resistance to human serum). WGS data and MS spectra confirmed that all veterinary isolates are closely related to the type strain V. cincinnatiensis NCTC12012. An exception was the human isolate from Germany which is related to the other isolates but could belong to another species. The isolates were similar in most biochemical phenotypes. Only one strain showed a very weak hemolytic activity against sheep erythrocytes, and serum resistance was intermediate in two strains. AMR phenotypes were more variable between the isolates. Resistances were observed against ß-lactams ampicillin and cefoxitin and against tetracycline and the sulfonamide antibiotics trimethoprim and sulfamethoxazole. Some acquired AMR genes were identified by bioinformatics analyses. WGS and MALDI-TOF MS data reveal a close relationship of the veterinary isolates and the type strain V. cincinnatiensis NCTC12012, which is a clinical human isolate. As the veterinary isolates of this study were mostly recovered from abortion material (amnions and fetuses), a zoonotic potential of the veterinary isolates seems possible.
- Published
- 2020
- Full Text
- View/download PDF
5. Determination of plasma concentrations of organochlorine pesticides and polychlorinated biphenyls in pet cats and dogs.
- Author
-
Yavuz O, Arslan HH, Esin C, Das YK, and Aksoy A
- Subjects
- Animals, Chromatography, Gas veterinary, Environmental Exposure statistics & numerical data, Female, Male, Turkey, Cats blood, Dogs blood, Hydrocarbons, Chlorinated blood, Pesticides blood, Polychlorinated Biphenyls blood
- Abstract
The aim of this study was the determination of plasma concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in cats and dogs and evaluation of their prevalence and possible effects. The concentrations of nine OCPs, such as α-hexachlorocyclohexane (HCH), β-HCH, γ-HCH, hexachlorobenzene (HCB), aldrin, 2,4'-dichlorodiphenyltrichloroethane (2,4'-DDT), 4,4'-DDT, 2,4'-dichlorodiphenyldichloroethylene (2,4'-DDE) and 4,4'-DDE and 16 PCBs (PCB-28, -52, -70, -74, -81, -99, -101, -118, -138, -153, -156, -170, -180, -183, -187 and -208) were evaluated in the plasma samples of pet cats ( n = 15) and dogs ( n = 21). The concentrations of OCPs ranged from 1.12 ng g
-1 lipid weight (lw) to 7.65 ng g-1 lw in cats and from 1.25 ng g-1 lw to 6.79 ng g-1 lw in dogs. In addition, mean PCB levels were 0.58-5.66 and 0.52-6.62 ng g-1 lw in cats and dogs, respectively. β-HCH, γ-HCH and PCB-138 levels were significantly higher in dogs ( p < 0.05). As far as could be determined, OCPs and PCBs were detected in the plasma samples of domestic cats and dogs in Turkey for the first time. Their concentrations were similar to those reported in earlier studies abroad. However, in contrast to other research, the levels of some OCPs were higher in dogs than in cats. It is concluded that, because of their high prevalence and potential health effects in animals and humans, OCP and PCB levels should be monitored systematically in domestic cats and dogs.- Published
- 2018
- Full Text
- View/download PDF
6. Changes in Proinflammatory Cytokines in the Cochlea in Relation to Hearing Thresholds in Noise-Exposed Rats.
- Author
-
Arslan HH, Satar B, Serdar M, and Yılmaz E
- Subjects
- Animals, Cochlea pathology, Euthanasia, Animal, Hearing, Inflammation, Male, Rats, Rats, Wistar, Cytokines physiology, Hearing Loss, Noise-Induced physiopathology, Interleukin-1beta physiology, Noise
- Abstract
Objective: Our aim was to investigate time effects in proinflammatory cytokines and the auditory brainstem response (ABR) thresholds of rat cochlea exposed to noise., Materials and Methods: Twenty-one rats were divided into two groups: the control group and the noise group. As high as 115 dB sound pressure of white noise was administered to the noise group of 16 rats for 3 h a day for 10 days. This group was further split into four subgroups based on the timing of sacrifice: 3rd hour group, 12th hour group, 24th hour group, and 28th day group. ABR thresholds were measured in all the rats, after the noise exposure and right before being sacrificed. Proinflammatory cytokine levels (IL-6, IL-1β, and TNF-α) at the cochlea were measured., Results: We found a significant difference between the first ABR thresholds (5 dB nHL) and the post-exposure ABR thresholds in each group (25 dBnHL, 35 dBnHL, 15 dBnHL, and 17.50 dBnHL for the 3rd hour group, 12th hour group, 24th hour group, and 28th day group, respectively). The IL-1β levels in the 3rd hour group and 12th hour group were significantly higher than those in the control group and other noise subgroups. The TNF-α level in the 3rd hour group was significantly higher than that in the control group and other noise subgroups., Conclusion: It seems reasonable to point out a direct correlation between the cytokine levels and hearing threshold levels after the noise exposure. This correlation was the highest for IL-1β. This result suggested a significant role of proinflammatory cytokines in hearing deterioration after noise exposure.
- Published
- 2017
- Full Text
- View/download PDF
7. Effects of thiocolchicoside, a commonly used myorelaxant, on the acoustic reflex.
- Author
-
Arslan HH, Cebeci S, Yildizoglu U, Pusat S, and Yavuz F
- Subjects
- Acoustic Impedance Tests methods, Adult, Audiometry, Pure-Tone methods, Colchicine administration & dosage, Colchicine adverse effects, Female, Hearing Loss, Noise-Induced etiology, Humans, Male, Middle Aged, Neuromuscular Agents administration & dosage, Noise adverse effects, Prospective Studies, Stapedius drug effects, Young Adult, Auditory Threshold drug effects, Colchicine analogs & derivatives, Hearing drug effects, Neuromuscular Agents adverse effects, Reflex, Acoustic drug effects
- Abstract
Objective: To determine whether thiocolchicoside, a commonly used myorelaxant, may impair the acoustic reflex., Methods: Forty-two patients scheduled to receive thiocolchicoside treatment for different reasons were enrolled in the study. Acoustic reflex thresholds at 500, 1000, 2000 and 4000 Hz were determined and analysed statistically pre-treatment and on the 5th day of treatment., Results: Increases were observed in the mean acoustic reflex thresholds on the 5th day of treatment compared to pre-treatment, at all frequencies, except right contralateral thresholds at 500 and 2000 Hz. These increases were statistically significant for right ipsilateral thresholds at 2000 and 4000 Hz, left ipsilateral thresholds at 500, 1000, 2000 and 4000 Hz, and left contralateral thresholds at 2000 and 4000 Hz (p ≤ 0.05), but not at other frequencies (p > 0.05)., Conclusion: Muscle relaxant drugs, especially those affecting the central nervous system, may weaken the stapedial muscle so that the ability of noise to cause acoustic trauma may become evident. For this reason, physicians should advise their patients to avoid loud noises when muscle relaxant therapy is prescribed.
- Published
- 2017
- Full Text
- View/download PDF
8. The Management of the Paranasal Sinus Osteomas.
- Author
-
Arslan HH, Tasli H, Cebeci S, and Gerek M
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Osteoma diagnosis, Paranasal Sinus Neoplasms diagnosis, Postoperative Period, Tomography, X-Ray Computed, Treatment Outcome, Young Adult, Endoscopy methods, Ethmoid Sinus, Frontal Sinus, Maxillary Sinus, Osteoma surgery, Paranasal Sinus Neoplasms surgery, Plastic Surgery Procedures methods
- Abstract
Objective: Osteoma is the most common benign tumor of the paranasal sinuses. The clinical characteristics and treatment of this disease remain controversial. The aim of this study is to determine the appropriate method of treatment approach according to the features of osteomas., Methods: Forty-one patients with paranasal sinus osteomas were included in the study. According to the location and the size of tumors, patients were followed up or operated. Surgical treatment was performed via external, endoscopic, or combined approaches for symptomatic patients. Routine physical and radiological evaluations were performed for follow-up in asymptomatic patients., Results: Paranasal sinus osteomas were found most common in frontal sinus (n = 26, 63.4%) followed by ethmoid sinus (n = 10, 24.3%), maxillary sinus (n = 4, 9.7%), and sphenoid sinus (n = 1, 2.4%). Of the patients with frontal sinus osteomas, the endoscopic approach was performed in 11 patients, external approach (osteoplastic flap) in 9, and combined (external + endoscopic) approach in 5 patients. Endoscopic approach was preferred in all patients with ethmoid osteoma. The combination of Caldwell-Luc procedure and endoscopic approach was performed in 1 patient with maxillary sinus osteoma. In 3 patients, who underwent osteoplastic flap technique, mucocele developed in the postoperative period. Partial loss of vision developed postoperatively in 1 patient with a giant ethmoid osteoma. There were no other complications and recurrence in an average of 29 months follow-up., Conclusion: Paranasal sinus osteomas are rare, slow-growing benign lesions, with potentially serious complications. Main treatment option for sphenoid and ethmoid sinus and other symptomatic osteomas are surgical resection. Radiographic follow-up is necessary for asymptomatic lesions. Selection of surgical resection method depends on tumor location and size. Patients should be observed for recurrence with periodic examination and imaging techniques. Follow-up should be performed at least in 1-year intervals after the surgery., Level of Evidence: 1c.
- Published
- 2017
- Full Text
- View/download PDF
9. [Treatment approaches to temporal bone osteomas].
- Author
-
Arslan HH, Gökgöz MC, Cebeci S, and Taşlı H
- Subjects
- Adolescent, Adult, Aged, Ear Canal, Female, Humans, Male, Mastoid surgery, Middle Aged, Osteoma diagnosis, Postoperative Period, Retrospective Studies, Temporal Bone pathology, Young Adult, Osteoma surgery, Temporal Bone surgery
- Abstract
Objectives: This study aims to evaluate treatment approaches in relation to the localization, size and symptoms of temporal bone osteoma according to the complaints of the patient., Patients and Methods: We retrospectively reviewed the records of 23 patients (16 males, 7 females; mean age 28.6 years; range 14-69 years) followed up with the diagnosis of temporal bone osteoma at our clinic between January 2005 and April 2016. We obtained the demographic features, clinical presentations (symptoms, location and size of the tumors), treatment approaches and postoperative outcomes of the patients from patients file. Treatment approaches were analyzed according to the characteristics of patients and of the tumor., Results: The most common localization of osteomas was external auditory canal (66%), followed by mastoid bone (21%) and middle ear cavity (13%). The osteoma was detected incidentally in five patients out of 23. Treatment approaches were determined according to the presence of symptoms, size and localization of tumors., Conclusion: Physical examination and periodic follow-up is recommended in asymptomatic patients. In symptomatic patients, surgical resection is needed with an appropriate surgical approach based on the location and size of the tumor.
- Published
- 2016
- Full Text
- View/download PDF
10. Life Priorities in Head and Neck Cancer Patients Between Ages of 45 to 65.
- Author
-
Arslan HH, Ahmadov A, Cebeci S, Binar M, and Karahatay S
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Activities of Daily Living psychology, Head and Neck Neoplasms psychology, Quality of Life, Surveys and Questionnaires
- Abstract
Diseases in head and neck cancer patients and applied therapies according to former affect life quality to a higher extent. In this paper, life priorities in 49 patients with head and neck cancer who referred to Gulhane Military Medical Academy for diagnostic and therapeutic purposes and the relationship between these priorities and sociodemographic properties have been studied. Following life priorities have been observed more important for the patients: to communicate with people in social places, to eat without any help by themselves, external appearance, taste and odor sense, continuing sexual life. Other priorities have been observed less important for the patients: attending social activities like cinema and theater, swimming pool and sea sports, money required for check-ups, necessities like time. Besides, these necessities do not show dissimilarities to any significant extent according to sociodemographic properties of the patients.
- Published
- 2016
- Full Text
- View/download PDF
11. Increased frequency of mitral valve prolapse in patients with deviated nasal septum.
- Author
-
Arslan HH, Aparci M, Arslan Z, Ozturk C, Isilak Z, Balta S, Celik T, and Iyisoy A
- Subjects
- Adult, Collagen metabolism, Echocardiography methods, Female, Humans, Male, Middle Aged, Mitral Valve pathology, Nasal Cartilages metabolism, Nasal Cartilages pathology, Retrospective Studies, Mitral Valve Prolapse complications, Mitral Valve Prolapse diagnosis, Nasal Septum pathology, Nose abnormalities, Nose Deformities, Acquired complications, Nose Deformities, Acquired diagnosis
- Abstract
Any abnormality of collagen may affect the tissues with higher collagen content, e.g., joints, heart valves, and great arteries. Mitral valve prolapse (MVP) is a characteristic of generalized collagen abnormality. Nasal septum (NS) is constituted by osseous and cartilaginous septums that are highly rich in collagen. We evaluated the co-existence of deviation of NS (DNS) in patients with MVP. We retrospectively evaluated the recordings of echocardiographic and nasal examinations of subjects with MVP and DNS. We analyzed the features of MVP and anatomical classification of DNS among subjects. Totally, 74 patients with DNS and 38 subjects with normal nasal passage were enrolled to the study. Presence of MVP was significantly higher in patients with DNS compared to normal subjects (63 vs 26%, p < 0.001). Prolapse of anterior, posterior and both leaflets was higher in patients with DNS. Thickness of anterior mitral leaflet was significantly increased in patients with DNS (3.57 ± 0.68 vs 4.59 ± 1.1 mm, p < 0.001) compared to normal subjects. Type I, II, and III, IV DNS were higher in frequency in patients with MVP while type V and VI were higher in normal subjects. DNS is highly co-existent with MVP and increased thickness of mitral anterior leaflet. Generalized abnormality of collagen which is the main component of mitral valves and nasal septum may be accounted for co-existence of MVP and DNS. Also co-existence of them may exaggerate the symptoms of patients with MVP due to limited airflow through the nasal passage.
- Published
- 2015
- Full Text
- View/download PDF
12. Evaluation of the changes in the nasal cavity during the migraine attack.
- Author
-
Arslan HH, Tokgöz E, Yildizoğlu Ü, Durmaz A, Bek S, and Gerek M
- Subjects
- Adolescent, Adult, Aged, Airway Resistance physiology, Endoscopy, Female, Humans, Male, Middle Aged, Nasal Mucosa physiopathology, Tension-Type Headache diagnosis, Tension-Type Headache physiopathology, Young Adult, Migraine Disorders diagnosis, Migraine Disorders physiopathology, Nasal Cavity physiopathology, Nasal Obstruction diagnosis, Nasal Obstruction physiopathology, Rhinomanometry
- Abstract
Objectives: There are some subjective symptoms involving the nasal cavity such as nasal congestion during a migraine attack. In this study, we aimed to evaluate the possible changes occurring in the nasal cavity during headache in patients with migraine., Materials and Methods: Patients with migraine were studied. The control group consisted of patients with tension-type headache. The severity of the headache and accompanying complaints were assessed using visual analog scale, and the nasal mucosa was assessed through anterior rhinoscopy and endoscopy. Resistance of the nasal cavity was evaluated through anterior rhinomanometry. Data obtained during the attack periods and attack-free periods were compared., Results: Twenty-five patients with migraine and 15 patients with tension-type headache were enrolled. It was found that 19 patients (76%) of the group with migraine and 5 patients of the group with tension-type headache were experiencing nasal congestion during the attack and that the differences between the groups were statistically significant (P < 0.05). The average of total nasal resistance in the patients with migraine was 0.57 ± 0.60 kPa/L/sn during migraine attacks and 0.28 ± 0.14 kPa/L/sn during attack-free periods. The average of total nasal resistance in the patients with tension-type headache was 0.32 ± 0.14 kPa/L/sn during attack periods and 0.31 ± 0.20 kPa/L/sn during attack-free periods. In the group with migraine, the change of nasal resistance between during the attack and attack-free periods was found statistically significant, whereas there was no statistically significant difference in the group with tension-type headache., Conclusions: According to the results of this study, complaints regarding nasal obstruction and nasal airway resistance increase during migraine attacks. Cause-and-effect relationship between nasal obstruction and pain is not clear, and clinical trials are needed to determine the effect of nasal obstruction treatment (mucosal decongestion, etc) on the complaint of pain.
- Published
- 2014
- Full Text
- View/download PDF
13. Validity of late-term electroneurography in Bell's palsy.
- Author
-
Arslan HH, Satar B, Yildizoglu U, Edizer DT, and Akgun H
- Subjects
- Acyclovir analogs & derivatives, Acyclovir therapeutic use, Adult, Aged, Anti-Inflammatory Agents therapeutic use, Antiviral Agents therapeutic use, Bell Palsy drug therapy, Electric Stimulation, Facial Muscles physiopathology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Predictive Value of Tests, Prednisolone therapeutic use, Prognosis, ROC Curve, Recovery of Function, Reproducibility of Results, Retrospective Studies, Valacyclovir, Valine analogs & derivatives, Valine therapeutic use, Young Adult, Bell Palsy diagnosis, Electrodiagnosis methods
- Abstract
Objective: To evaluate the validity of early (within 3 wk) and late-term (after 3 wk) electroneurography (ENoG) findings in Bell's palsy (BP) to predict the prognosis., Study Design: Retrospective case review., Setting: Tertiary referral center., Patients: Patients with peripheral facial paralysis with no identified cause. All patients were given the same treatment., Intervention(s): House Brackmann (HB) grading and ENoG., Main Outcome Measures: The records of 38 patients with BP were retrospectively analyzed. This study included only those patients who had been followed up for at least 4 months on a regular basis or until complete recovery. ENoG was performed for orbicularis oculi and orbicularis oris muscles and degeneration ratio was calculated separately. Correlation between HB grading and ENoG findings, relationship between duration for maximum recovery and ENoG findings, and also initial HB grading and recovery rate were investigated., Results: Complete recovery rate was significantly higher in patients with HB grades I to III at initial examination. A significant correlation was found between HB grading and degree of ENoG degeneration at the 7th and 14th days of FP. Patients with degeneration less than 80% for orbicularis oculi and less than 65% for orbicularis oris had significantly better and faster recovery than those with higher level of degeneration (p < 0.05)., Conclusion: ENoG and HB grading during first to fourth weeks of BP are useful prognostic indicators. Serial ENoG examinations are recommended to predict the status of neural degeneration and the prognosis of the palsy. However, ENoG in late term may not be compatible with clinical facial function.
- Published
- 2014
- Full Text
- View/download PDF
14. Diagnostic utility of Stenger test: reappraisal of its value.
- Author
-
Arslan HH, Edizer DT, Cebeci S, and Erdal M
- Abstract
Objective: Nonorganic hearing loss (NOHL) is a lack of consistency in audiological testing. Although NOHL is relatively rare, it is important to identify suspicious patients. This study was designed to evaluate the effectiveness of Stenger test and acoustic reflexes test (ART) in the evaluation of patients with suspicious of unilateral NOHL., Study Design: A prospective study Methods: In this study, 474 adult patients with suspicious unilateral profound or total hearing loss were included. Pure tone audiometry (PTA), speech audiometry, Stenger test, ART and click-evoked auditory brainstem response (ABR) measurements were performed. The sensitivity, specificity and predictive values of the Stenger test and ART for unilateral, profound to total NOHL were assessed by comparing these with the results of ABR., Results: The sensitivity and specificity of the Stenger test in verifying unilateral, profound hearing loss were 99% and 57%, respectively. The positive and negative predictive values of the test were 88% and 97%, respectively. The sensitivity and specificity of the ART in verifying unilateral, profound hearing loss were 96% and 60% at 1000 Hz and 98% and 60% at 2000 Hz, respectively. The positive and negative predictive values of the ART were 50% and 97% at 1000 Hz, and 75% and 97% at 2000 Hz, respectively., Conclusion: The Stenger test and ART are widely used for the evaluation of unilateral or asymmetrical NOHL. In our opinion, these tests are significantly powerful. More difficult cases require ABR to verify nonorganic hearing loss and to exclude specific diagnoses that may imitate NOHL.
- Published
- 2014
- Full Text
- View/download PDF
15. Nasalance scores for normal-speaking Turkish population.
- Author
-
Karakoc O, Akcam T, Birkent H, Arslan HH, and Gerek M
- Subjects
- Adolescent, Adult, Aged, Child, Female, Humans, Male, Middle Aged, Nose, Reference Values, Turkey, Speech Articulation Tests
- Abstract
Objective: The aim of this study was to obtain normative nasalance scores for adult and children subjects speaking Turkish language and obtain a reference for normality when nasality is evaluated., Methods: Mean nasalance scores were obtained from 35 normal-speaking children aged 7 to 13 years, and 125 adults aged 18 to 69 years during the repetition of 3 nasalance passages that were categorized according to the amount of nasal consonants (oral, oronasal, and nasal passages). The Nasometer (model 6400) was used to obtain nasalance scores for the 3 reading passages., Results: Group mean ± SD nasalance scores of children for oral passage, oronasal passage, and nasal passage were 15.14 ± 4.81, 37.76 ± 4.42, and 49.23 ± 6.95, respectively. Nasalance scores for the adult group were 13.46 ± 6.26, 37.84 ± 6.13, and 50.28 ± 7.77, respectively. There were significant differences in mean nasalance scores for oral versus nasal materials both for children and adult groups., Conclusions: The present study provides normative nasalance scores for Turkish-speaking children and adults. The results indicated acceptable differentiation between oral and nasal materials.
- Published
- 2013
- Full Text
- View/download PDF
16. Comparison of early postoperative pain among surgical techniques for obstructive sleep apnea.
- Author
-
Akcam T, Arslan HH, Deniz S, Genc H, Karakoc O, Senkal S, and Gerek M
- Subjects
- Adult, Analgesics, Opioid therapeutic use, Cohort Studies, Female, Humans, Male, Middle Aged, Pain Measurement, Pain, Postoperative drug therapy, Prospective Studies, Severity of Illness Index, Tramadol therapeutic use, Analgesia, Patient-Controlled statistics & numerical data, Otorhinolaryngologic Surgical Procedures methods, Pain, Postoperative epidemiology, Sleep Apnea, Obstructive surgery
- Abstract
One of the criticized aspects of surgeries for obstructive sleep apnea (OSA) is postoperative pain. We performed a study to compare the severity of pain occurring after different surgical techniques and to determine analgesic requirements in the first postoperative 24 h. Forty-eight patients with primary snoring or OSA who underwent anterior palatoplasty (AP), lateral pharyngoplasty (LP) or tongue base suspension suture (TBS) were included in this study. A visual analog scale (VAS) was used for measuring pain intensity. Tramadol with patient-controlled analgesia (PCA) device and when necessary rescue pethidine was used for pain relief. VAS pain scores, total PCA-tramadol consumptions and requirement of rescue analgesic in AP, LP and TBS groups were compared. Pain scores in TBS group were higher than AP group in all of the study time points except at 12th hour and LP group until the 10th hour. When compared with AP group, VAS was significantly higher in LP group at the 1st hour. Mean total tramadol consumptions were significantly different between the groups (AP-LP, p = 0.039; AP-TBS, p < 0.001; LP-TBS, p < 0.001). It was highest in the TBS group and lowest in the AP group. In the LP group, three patients (16.7 %) needed rescue analgesia in comparison with 11 (73.3 %) in the TBS group. None of the patients in the AP group needed rescue analgesic. AP is the least painful and TBS is the most painful procedure. PCA-bolus tramadol effectively treats pain caused by AP and LP; however, alleviation of pain caused by TBS usually needs rescue opioid analgesic.
- Published
- 2012
- Full Text
- View/download PDF
17. Subcutaneous approximation suture for preventing soft tissue pollybeak deformity.
- Author
-
Tosun F, Arslan HH, Hidir Y, Karslioglu Y, Durmaz A, and Gerek M
- Subjects
- Animals, Rabbits, Cicatrix prevention & control, Nose Deformities, Acquired prevention & control, Postoperative Complications prevention & control, Rhinoplasty adverse effects, Subcutaneous Tissue surgery, Suture Techniques
- Abstract
Background: Pollybeak deformity due to abundant fibrosis formation in the supratip region after rhinoplasty is still a common problem. The aim of this study was to investigate the effects of a modified subcutaneous approximation suture on pollybeak deformity of soft tissue origin., Methods: Three groups, each consisting of eight rabbits, were included in the study. Nasal skin was elevated with an open rhinoplasty approach in all groups. During closure of the skin, to minimize supratip dead space, a horizontal subcutaneous approximation suture was used in group I, external tape fixation was used in group II, and no further action was taken for supratip skin approximation in the control group. Full-thickness supratip skin biopsy specimens reaching down to the underlying cartilage tissue were taken from each subject on the 60th day after the operation. Thicknesses of subcutaneous scar tissues were measured histologically in all groups and compared., Results: The mean thickness of the subcutaneous scar tissues was significantly lower (0.98 ± 0.32 mm) in group I than in group II (1.65 ± 0.61 mm; p = 0.036) and the control group (1.72 ± 0.49 mm; p = 0.019). However, there were no significant differences between group II and the control group in the mean thickness of subcutaneous scar tissues (p = 1.000)., Conclusion: The findings of this study indicate that the subcutaneous approximation suture is effective for preventing excessive scar tissue formation in the supratip area after rhinoplasty in rabbits. Further clinical studies are needed to determine its efficacy in humans.
- Published
- 2012
- Full Text
- View/download PDF
18. HASTE diffusion-weighted MRI for the reliable detection of cholesteatoma.
- Author
-
Ilıca AT, Hıdır Y, Bulakbaşı N, Satar B, Güvenç I, Arslan HH, and Imre N
- Subjects
- Adolescent, Adult, Aged, Cholesteatoma, Middle Ear pathology, Cohort Studies, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Otologic Surgical Procedures methods, Prospective Studies, Recurrence, Reference Values, Reoperation methods, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index, Young Adult, Cholesteatoma, Middle Ear diagnosis, Cholesteatoma, Middle Ear surgery, Diffusion Magnetic Resonance Imaging methods, Image Processing, Computer-Assisted
- Abstract
Purpose: To assess the detection efficiency of Half-Fourier acquisition single-shot turbo spin-echo (HASTE) diffusion-weighted magnetic resonance imaging (MRI) for cholesteatoma., Materials and Methods: A total of 21 patients with suspected primary (n=16) or recurrent cholesteatoma (n=5) underwent MRI in a 1.5 Tesla scanner using an adapted protocol for cholesteatoma detection that included a coronal HASTE diffusion-weighted MRI sequence. The cholesteatoma diagnosis was based on evidence of a hyperintense lesion at b-1000 on diffusion-weighted images. The imaging findings were correlated with findings from surgery or clinical evaluations in all patients., Results: HASTE diffusion-weighted MRI successfully detected 11 primary and 5 recurrent lesions out of 17 cholesteatomas (sensitivity, 94.1%). One primary cholesteatoma with a diameter of 4-5 mm was missed. MRI of patients without cholesteatoma were correctly interpreted as negative for cholesteatoma (specificity, 100%). The positive and negative predictive values for the HASTE diffusion-weighted MRI in detecting cholesteatoma were 100% and 80%, respectively., Conclusion: HASTE diffusion-weighted MRI offers great promise for cholesteatoma screening. The addition of this sequence to the posterior fossa MRI protocol may preclude unnecessary cholesteatoma surgery.
- Published
- 2012
- Full Text
- View/download PDF
19. TMJ herniation associated with lymphangioma of the parotid region.
- Author
-
Satar B, Arslan HH, Ugurel S, and Hidir Y
- Subjects
- Angiography, Digital Subtraction, Audiometry, Pure-Tone, Diagnosis, Differential, Hearing Loss, Conductive diagnosis, Hernia diagnosis, Humans, Lymphangioma diagnosis, Male, Parotid Neoplasms diagnosis, Temporomandibular Joint Disorders diagnosis, Tomography, X-Ray Computed, Young Adult, Hearing Loss, Conductive etiology, Hernia etiology, Lymphangioma complications, Parotid Neoplasms complications, Temporomandibular Joint Disorders etiology
- Abstract
Objective: The objective of this study was to present clinical, audiological, and radiologic findings of a rare case of the temporomandibular joint herniation associated with lymphangioma of the parotid region., Clinical Report: A 21-year-old man with the complaints of a mass on the right side of the face, otalgia, and hearing loss in the right ear was referred to our department. The examination revealed a herniating temporomandibular joint into the right external auditory meatus when the patient closed his mouth. He had also hearing loss when he closed his mouth. Upon opening the mouth, the temporomandibular joint returned into its normal position within the glenoid fossa, and the hearing became normal. The patient had also lymphangioma involving mainly the parotid region., Conclusions: Temporomandibular joint herniation into the external auditory meatus may be rarely due to parotid lymphangioma, which leads to pseudo-conductive hearing loss.
- Published
- 2012
- Full Text
- View/download PDF
20. Case report: nodular fasciitis of the parotid region.
- Author
-
Hidir Y, Arslan HH, Gunhan O, and Satar B
- Subjects
- Biopsy, Fine-Needle, Diagnosis, Differential, Fasciitis pathology, Fasciitis surgery, Humans, Male, Myofibroblasts, Parotid Diseases pathology, Parotid Diseases surgery, Young Adult, Fasciitis diagnosis, Parotid Diseases diagnosis, Parotid Region
- Abstract
Objective: To demonstrate the clinical and histopathological features of nodular fasciitis in the parotid region., Case Report: A 24-year-old man presented with a palpable mass in the superior border of the parotid gland. The mass was firm and immobile, with a smooth surface. Fine needle aspiration cytology revealed proliferating fibroblasts, macrophages and adipocytes among the blood cells. Although a superficial parotidectomy was initially planned, a total excision was performed, as the mass was observed to be located in the periphery of the parotid tissue. Nodular fasciitis was diagnosed, based on the results of immunohistochemical analysis., Conclusion: Nodular fasciitis very rarely occurs in the parotid region. These lesions grow quickly, and may be misdiagnosed as sarcoma. Trauma may play a role in their aetiology. Total excision is adequate as treatment.
- Published
- 2011
- Full Text
- View/download PDF
21. Unexpected tumor incidence in surgically removed unilateral and bilateral nasal polyps.
- Author
-
Arslan HH, Hidir Y, Durmaz A, Karslioglu Y, Tosun F, and Gerek M
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Endoscopy, Female, Humans, Incidence, Incidental Findings, Male, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed, Turkey epidemiology, Nasal Polyps pathology, Nasal Polyps surgery, Nose Neoplasms epidemiology
- Abstract
Objective: The objective of the study was to investigate the postoperative tumor incidence on routine histopathologic examination of surgical specimens in patients who underwent endoscopic sinus surgery with the preoperative diagnosis of unilateral or bilateral nasal polyposis., Methods: Patients who underwent endoscopic sinus surgery with the preoperative diagnosis of unilateral or bilateral nasal polyposis between 2000 and 2009 were included in the study as the 2 separate groups. In both groups, tumor incidence that had been noticed on routine postoperative histopathologic examination was recorded retrospectively. Patients who had a preoperative diagnosis other than nasal polyposis, determined on biopsy, were excluded., Results: Of 251 patients included, 197 had the preoperative diagnosis of bilateral nasal polyposis, and 54 had unilateral nasal polyposis. No tumor was diagnosed on postoperative histopathologic examinations in patients with preoperative bilateral nasal polyposis. Seven patients (12.96%) with the preoperative diagnosis of unilateral nasal polyposis had tumors on postoperative histopathologic examinations. Two of these 7 patients had malignant tumors that were reported preoperatively by intranasal biopsy as inflammatory polyps., Conclusions: Diagnosis of a neoplasia is an extremely rare situation, unless there are special findings of tumor in patients with preoperative diagnosis of bilateral nasal polyposis. On the other hand, histopathologic examinations should be carried out in every case operated with preoperative diagnosis of unilateral nasal polyposis, as the tumor incidence is higher.
- Published
- 2011
- Full Text
- View/download PDF
22. Thyroglossal duct cysts: evaluation and treatment of 49 cases.
- Author
-
Yaman H, Durmaz A, Arslan HH, Ozcan A, Karahatay S, and Gerek M
- Subjects
- Adolescent, Adult, Cell Transformation, Neoplastic, Child, Female, Humans, Middle Aged, Retrospective Studies, Thyroglossal Cyst pathology, Young Adult, Thyroglossal Cyst diagnosis, Thyroglossal Cyst surgery
- Abstract
Objective: The aim of the study was to evaluate the clinical features and treatment outcomes of patients with a thyroglossal duct cyst (TGDC) or fistula., Methods: The records of 49 patients (9 female, 40 male; mean age: 23.16 +/- 1.13 years; range 6 to 56 years) operated on between January 1995 and July 2009 were reviewed retrospectively. Patient's age, sex, duration of symptoms, clinical features, pre-operative diagnostic tests, treatment, histopathologic diagnosis, and post-operative complications were noted. All patients underwent the Sistrunk procedure., Results: Fifteen patients (30.6%) were < or = 20 years old, while 3 (6.1%) patients were 40 years old at the time of operation. There was cyst formation in 26 patients (53.1%) and fistula formation in 23 patients (46.9%). The lesions of 41 patients (83.7%) were located in the midline, while the lesions of 8 patients (16.3%) were located in the paramedian neck (5 left side, 3 right side). The most common presenting symptoms were painless mass in the midline of the neck and recurrent suppuration of fistula formation. Neck ultrasonography (USG) was the most common pre-operative diagnostic procedure and was performed on all patients with cyst formations. There were no major complications postoperatively. There was recurrence in only one patient after the Sistrunk procedure. One patient was incidentally diagnosed with thyroid papillary carcinoma after histopathological examination., Conclusions: A TGDC is the most common congenital mass in the neck and is usually located midline. USG is suggested for a clinically suspected TGDC. The Sistrunk procedure is a safe and successful technique with low complication and recurrence rates. Even though carcinomas arising in TGDCs are uncommon, histopathological examination must be routinely performed to confirm the diagnosis and rule out malignancy.
- Published
- 2011
23. Myoepithelioma of the parotid gland in a child: a case report.
- Author
-
Yaman H, Gerek M, Tosun F, Deveci S, Kiliç E, and Arslan HH
- Subjects
- Adolescent, Female, Humans, Tomography, X-Ray Computed, Myoepithelioma pathology, Myoepithelioma surgery, Parotid Neoplasms pathology, Parotid Neoplasms surgery
- Abstract
Myoepitheliomas of the parotid glands are very rare in the pediatric population. Only a few cases of myoepitheliomas of the salivary glands have been reported in children. They have some similar features with pleomorphic adenoma. However, they may be malignant and infiltrate locally. Hence, histopathologic examination should be considered to differentiate these tumors. The treatment of myoepitheliomas is complete removal of the tumor. We report a child with myoepithelioma of the parotid gland and review the related literature., (Copyright 2010 Elsevier Inc. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
24. Relationship between postoperative recurrence rate and eosinophil density of nasal polyps.
- Author
-
Tosun F, Arslan HH, Karslioglu Y, Deveci MS, and Durmaz A
- Subjects
- Adult, Aged, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Nasal Polyps pathology, Postoperative Complications blood, Recurrence, Young Adult, Eosinophils physiology, Leukocyte Count, Nasal Polyps blood, Nasal Polyps surgery
- Abstract
Objectives: Nasal polyps develop as a result of chronic inflammation, mostly accompanied by pronounced eosinophil leukocyte infiltration. In this study we aimed to investigate the relationship between eosinophil density in nasal polyps and the postoperative recurrence rate of this disease., Methods: Forty-two patients who underwent endoscopic sinus surgery for massive nasal polyposis by one surgeon were included in the study. The eosinophil leukocyte densities in nasal polyps were determined retrospectively on histologic slides by use of computer-assisted image analysis software. The patients were assigned to group 1, in whom nasal polyps contained up to 3 eosinophils per 1,000 microm2, and group 2, in whom nasal polyps contained 4 or more eosinophils per 1,000 microm2. The postoperative recurrence rates of nasal polyps were compared in the two groups., Results: There were 20 patients in group 1 and 22 patients in group 2. Postoperative polyp recurrence was detected in 5 of 20 patients (25.0%) in group 1 and in 18 of 22 patients (81.8%) in group 2 during the 30-month postoperative followup period (p < 0.05)., Conclusions: The eosinophil density of nasal polyps can be used to get an estimate of the postoperative recurrence risk. Eosinophil-rich nasal polyps have a higher postoperative recurrence rate.
- Published
- 2010
- Full Text
- View/download PDF
25. Analysis of jugular foramen exposure in the fallopian bridge technique.
- Author
-
Satar B, Yazar F, Ceyhan A, Arslan HH, and Aydin S
- Abstract
Objective: To analyze the exposure of the jugular foramen afforded by the fallopian bridge technique., Method: The jugular foramen exposure was obtained using the jugular foramen approach combined with the fallopian bridge technique. We applied this technique using 10 temporal bone specimens at a tertiary referral center. The exposure was assessed by means of depth of the dissection field and two separate dissection spaces that were created anteriorly and posteriorly to the facial nerve. Anteroposterior and superoinferior dimensions of the anterior dissection space were 4.4 +/- 1.03 mm and 6.3 +/- 2.49 mm, respectively. The superoinferior and anteroposterior dimensions of the posterior dissection space were 11.7 +/- 2.08 mm and 8.0 +/- 2.95 mm, respectively. The depth of the first dissection field was 8.2 +/- 2.11 mm. After perforating the jugular bulb, the depth of the second dissection field was 16.0 +/- 1.60 mm., Results: The anterior dissection space serves only as an additional visualization space for anatomical orientation to the jugular bulb. Tumor dissection is to be accomplished mainly through the posterior dissection space., Conclusion: The fallopian bridge technique should be added to surgical armamentarium for the jugular foramen tumors confined only to the jugular fossa or tumors with middle ear extension.
- Published
- 2009
- Full Text
- View/download PDF
26. Seroprevalence of equine babesiosis in the Black Sea region of Turkey.
- Author
-
Acici M, Umur S, Guvenc T, Arslan HH, and Kurt M
- Subjects
- Animals, Babesiosis epidemiology, Babesiosis parasitology, Equidae parasitology, Fluorescent Antibody Technique, Indirect, Horse Diseases parasitology, Horses parasitology, Prevalence, Theileria immunology, Theileriasis epidemiology, Theileriasis parasitology, Turkey epidemiology, Antibodies, Protozoan blood, Babesia immunology, Babesiosis veterinary, Horse Diseases epidemiology
- Abstract
The prevalence of Theileria equi and Babesia caballi was determined in equid blood samples in five provinces of the Black Sea region of Turkey by using the indirect fluorescent antibody test (IFAT). Of 153 samples, 53 (34.6%) and 33 (21.5%) were seropositive to B. caballi and T. equi, respectively. In addition, 8 (5.2%) of samples were seropositive to both T. equi and B. caballi. Anti T. equi and B. caballi antibodies were detected in all five regions. The prevalence of B. caballi was higher than T. equi in all counties. Antibodies to T. equi and B. caballi were detected in horses of all ages, and there were no significant differences among age groups. Out of 84 horses, 32 (38.0%) were positive for B. caballi infection and 20 (23.8%) were positive for T. equi infection. Five horses (5.6%) were found to be seropositive to both B. caballi and T. equi. Of 38 donkeys, 14 (36.8%) were found to be positive for B. caballi infection and 5 (13.1%) positive for T. equi infection. In addition, 2 (5.2%) samples were seropositive for both T. equi and B. caballi infections. Out of 31 mules, 8 (25.8%) were positive for B. caballi infection and 8 (25 8%) positive for T. equi infection. One (3.2%) sample was seropositive for both T. equi and B. caballi infections. Of all the animals in this study, only 3 horses were infected by Rhipicephalus turanicus and Hyalomma detritum, and no haemoparasites were detected by microscopic examination.
- Published
- 2008
- Full Text
- View/download PDF
27. [Psoroptes cuniculi infestation in four rabbits and treatment with ivermectin].
- Author
-
Arslan HH, Açici M, Umur S, and Hökelek M
- Subjects
- Animals, Female, Male, Mite Infestations drug therapy, Treatment Outcome, Insecticides therapeutic use, Ivermectin therapeutic use, Mite Infestations veterinary, Psoroptidae, Rabbits parasitology
- Abstract
Psoroptes cuniculi for treatment and in 10 rabbits in contact with the infested animals for protection. The efficacy of the drug was evaluated based on the clinical signs, the absence of live mites and new clinical cases during a period of least two weeks. Elimination of clinical signs and mites were seen in three rabbits seven days after the ivermectin injection, but one rabbit, which had meningitis-like signs, died. Also, no new cases occurred in the other ten rabbits. These results suggest that an application of ivermectin can completely eliminate mites from rabbits naturally infested with P. cuniculi and that it was also a sufficient method for protection from contact infestation.
- Published
- 2008
28. Effects of trichophytosis on serum zinc levels in calves.
- Author
-
Nisbet C, Yarim GF, Ciftci G, Arslan HH, and Ciftci A
- Subjects
- Animals, Cattle, Dermatomycoses blood, Erythrocyte Indices, Erythrocytes metabolism, Hematocrit, Hemoglobins metabolism, Lymphocytes metabolism, Monocytes metabolism, Spectrophotometry, Atomic methods, Tinea blood, Zinc blood
- Abstract
The purpose of this study was to determine the zinc levels in calves with trichophytosis and to research the importance of zinc for fungi. The sera of 20 calves with trichophytosis and 10 healthy calves were used in this study. Zinc levels of the sera were measured by the atomic absorption spectrophotometer method. Serum zinc levels of diseased and healthy animals were found to be 42.0+/-16.6 microg/dL and 75.8+/-5.9 microg/dL, respectively. Serum zinc levels of diseased calves were lower than healthy ones and this difference were found to be important statistically (p<0.001), whereas there is no statistical difference on the levels of lymphocyte, monocyte, granulocyte, erythrocyte, hemoglobin, hematocrit, and mean corpuscular volume between groups. These parameters were not influenced by low zinc levels.
- Published
- 2006
- Full Text
- View/download PDF
29. Occurrence of ovine herpesvirus type-2 infection in sheep and cattle in Samsun Province, Turkey.
- Author
-
Yazici Z, Arslan HH, Gumusova SO, Meral Y, and Albayrak H
- Subjects
- Animals, Cattle, Enzyme-Linked Immunosorbent Assay methods, Enzyme-Linked Immunosorbent Assay veterinary, Female, Polymerase Chain Reaction methods, Polymerase Chain Reaction veterinary, Rhadinovirus isolation & purification, Seroepidemiologic Studies, Sheep, Sheep Diseases diagnosis, Turkey epidemiology, Antibodies, Viral blood, Malignant Catarrh diagnosis, Malignant Catarrh epidemiology, Rhadinovirus immunology, Sheep Diseases epidemiology
- Abstract
July 2004, a cow with clinical signs of ovine herpesvirus type-2 infection which is known as sheep associated malignant catarrhal fever (SA-MCF) was reported in Samsun Province in Turkey. Blood samples were collected from the suspected cow, 10 sheep housed with it, and from 150 healthy sheep and 29 healthy cattle randomly selected from different places in Samsun Province. Nested polymerase chain reaction (n-PCR) was used to detect ovine herpesvirus type-2 (OvHV-2) DNA in the suspected cow and competitive- ELISA (c-ELISA) kits were used to detect antibodies against OvHV-2. The suspected cow was found to be n-PCR positive and c-ELISA negative. The serological results were as follows: All 10 (100%) of sheep housed with the suspected cow and 18 of 29 (62%) of the randomly selected cattle were found seropositive. All 150 randomly selected healthy sheep were seronegative. The overall percentage of seropositivity was 14.7% (28/190). OvHV-2 DNA was detected in the peripheral blood leucocyte (PBL) samples of the cow and of the 10 sheep housed with the suspected cow.
- Published
- 2006
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.