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1. Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series

Author

Nucera E, Urbani S, Buonomo A, De Pasquale T, Rizzi A, Aruanno A, and Pucci S

Subjects
gadolinium-based contrast agents, hypersensitivity, ige-mediated reactions, Immunologic diseases. Allergy, RC581-607
Abstract

Eleonora Nucera,1 Sara Urbani,1 Alessandro Buonomo,1 Tiziana De Pasquale,2 Angela Rizzi,1 Arianna Aruanno,1 Stefano Pucci2 1Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; 2Civitanova Marche Hospital, Civitanova Marche, ItalyCorrespondence: Eleonora NuceraAllergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo F. Vito, 1, Rome, 00168, ItalyTel +39 3394475931Fax +06 30156999Email eleonora.nucera@policlinicogemelli.itAbstract: Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.Keywords: gadolinium-based contrast agents, hypersensitivity, IgE-mediated reactions

Published
2021

2. Latex Allergy: Current Status and Future Perspectives

Author

Nucera E, Aruanno A, Rizzi A, and Centrone M

Subjects
latex, immunotherapy, desensitization., Immunologic diseases. Allergy, RC581-607
Abstract

Eleonora Nucera,* Arianna Aruanno,* Angela Rizzi,* Michele Centrone* Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy*These authors contributed equally to this workCorrespondence: Eleonora NuceraAllergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCSS, Largo F. Vito, 1, Rome 00168, ItalyEmail eleonora.nucera@policlinicogemelli.itAbstract: Allergy to natural rubber latex (NRLA) from Hevea brasiliensis is a relevant public health issue, in particular in healthcare workers and groups at risk. Clinical manifestations of NRLA can range from mild skin disorders to life-threatening systemic reactions. Prevention measures remain the gold-standard treatment for patients suffering from NRLA, but the only etiological therapy able to influence the natural history of NRLA is specific desensitization. This review aims to underline the epidemiological, clinical and diagnostic aspects of NRLA, and carries out a complete and wide-ranging review of the current literature on NRLA management and immunotherapy.Keywords: latex, immunotherapy, desensitization

Published
2020

4. VR Lab: An Engaging Way for Learning Engineering and Material Science

Author

Aruanno, Beatrice, Tamburrino, Francesco, Neri, Paolo, Barone, Sandro, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Carfagni, Monica, editor, Furferi, Rocco, editor, Di Stefano, Paolo, editor, and Governi, Lapo, editor

Published
2024
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5. Effects of Printing Speed and Thermal Post-processing Treatments on the Mechanical Properties of PEEK Processed by Fused Deposition Modeling

Author

Tamburrino, Francesco, Aruanno, Beatrice, Paoli, Alessandro, Razionale, Armando Viviano, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Carfagni, Monica, editor, Furferi, Rocco, editor, Di Stefano, Paolo, editor, and Governi, Lapo, editor

Published
2024
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9. Tintoretto Unveiled: Interactive Virtual Experience for Artworks

Author

Aruanno, Beatrice, Barone, Sandro, Tamburrino, Francesco, Covarrubias Rodriguez, Mario, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Haddar, Mohamed, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Gerbino, Salvatore, editor, Lanzotti, Antonio, editor, Martorelli, Massimo, editor, Mirálbes Buil, Ramón, editor, Rizzi, Caterina, editor, and Roucoules, Lionel, editor

Published
2023
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10. Semi-automatic Point Clouds Registration for Upper Limb Anatomy

Author

Neri, Paolo, Aruanno, Beatrice, Barone, Sandro, Paoli, Alessandro, Razionale, Armando Viviano, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Haddar, Mohamed, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Gerbino, Salvatore, editor, Lanzotti, Antonio, editor, Martorelli, Massimo, editor, Mirálbes Buil, Ramón, editor, Rizzi, Caterina, editor, and Roucoules, Lionel, editor

Published
2023
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11. Severe Asthma Network Italy Definition of Clinical Remission in Severe Asthma: A Delphi Consensus

Author

Canonica, Giorgio Walter, Blasi, Francesco, Carpagnano, Giovanna Elisiana, Guida, Giuseppe, Heffler, Enrico, Paggiaro, Pierluigi, Allegrini, Chiara, Antonelli, Andrea, Aruanno, Arianna, Bacci, Elena, Bagnasco, Diego, Beghè, Bianca, Bonavia, Marco, Bonini, Matteo, Brussino, Luisa, Caiaffa, Maria Filomena, Calabrese, Cecilia, Camiciottoli, Gianna, Caminati, Marco, Caruso, Cristiano, Cavallini, Mirta, Chieco Bianchi, Fulvia, Conte, Maria Elisabetta, Corsico, Angelo Guido, Cosmi, Lorenzo, Costantino, Mariateresa, Costanzo, Giulia, Crivellaro, Mariaangiola, D'Alò, Simona, D'Amato, Mariella, Detoraki, Aikaterini, Di Proietto, Maria Carmela, Facciolongo, Nicola Cosimo, Ferri, Sebastian, Fierro, Vincenzo, Foschino, Maria Pia, Latorre, Manuela, Lombardi, Carlo, Macchia, Luigi, Milanese, Manlio, Montagni, Marcello, Parazzini, Elena Maria, Parente, Roberta, Passalacqua, Giovanni, Patella, Vincenzo, Pelaia, Girolamo, Pini, Laura, Puggioni, Francesca, Ricciardi, Luisa, Ridolo, Erminia, Rolo, Joyce, Scichilone, Nicola, Scioscia, Giulia, Senna, Gianenrico, Solidoro, Paolo, Varricchi, Gilda, Vianello, Andrea, Yacoub, Mona Rita, and Yang, Baoran

Published
2023
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12. San Pietro Al Monte Abbey: An Inclusive Virtual Tour

Author

Covarrubias, Mario, Aruanno, Beatrice, Polo, Laura, Barazzetti, Luigi, Roncoroni, Fabio, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Furferi, Rocco, editor, Governi, Lapo, editor, Volpe, Yary, editor, Seymour, Kate, editor, Pelagotti, Anna, editor, and Gherardini, Francesco, editor

Published
2022
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13. Mollusk allergy in shrimp-allergic patients: Still a complex diagnosis. An Italian real-life cross-sectional multicenter study

Author

Scala, Enrico, Abeni, Damiano, Aruanno, Arianna, Boni, Elisa, Brusca, Ignazio, Cappiello, Francesca, Caprini, Elisabetta, Buzzulini, Francesca, Deleonardi, Gaia, Demonte, Antongiulio, Farioli, Laura, Lodi Rizzini, Fabio, Michelina Losappio, Laura, Macchia, Donatella, Manzotti, Giuseppina, Meneguzzi, Giorgia, Montagni, Marcello, Nucera, Eleonora, Onida, Rosa, Pastorello, Elide Anna, Peveri, Silvia, Radice, Anna, Rivolta, Federica, Rizzi, Angela, Giani, Mauro, Cecchi, Lorenzo, Pinter, Elena, Miglionico, Marzia, Vantaggio, Lorenzo, Pravettoni, Valerio, Villalta, Danilo, and Asero, Riccardo

Published
2022
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17. Peanut allergy in Italy: A unique Italian perspective

Author

Asero, Riccardo, Nucera, Eleonora, Rizzi, Angela, Aruanno, Arianna, Uasuf, Carina G., Manzotti, Giuseppina, Villalta, Danilo, Conte, Mariaelisabetta, Pastorello, Elide A., Losappio, Laura, Schroeder, Jan V., Pinter, Elena, Miglionico, Marzia, Vantaggio, Lorenzo, Macchia, Donatella, Radice, Anna, Marra, Alessandro M., Barzaghi, Claudio, Santucci, Annalisa, Cortellini, Gabriele, Peveri, Silvia, Montagni, Marcello, Demonte, Antongiulio, Borrelli, Paolo, Errico, Micol A., Rivolta, Federica, Pravettoni, Valerio, Sangalli, Andrea, Magnani, Monica, Celi, Giorgio, Yang, Baoran, Costantino, Maria T., Deleonardi, Gaia, Boni, Elisa, Gattoni, Marco, Rizzini, Fabio Lodi, Di Paolo, Camilla, Montera, Mariacarmela, Giordano, Annaclaudia, De Carli, Marco, Murzilli, Francesco, Fumagalli, Federica, Maffeis, Laura, Ghiglioni, Daniele Giovanni, Centonze, Simone, Di Lizia, Michela, Calafiore, Paolo, and Scala, Enrico

Published
2022
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20. Virtual and Augmented Reality Platform for Cognitive Tele-Rehabilitation Based System

Author

Aruanno, Beatrice, Caruso, Giandomenico, Rossini, Mauro, Molteni, Franco, Espinoza, Milton Carlos Elias, Covarrubias, Mario, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Miesenberger, Klaus, editor, Manduchi, Roberto, editor, Covarrubias Rodriguez, Mario, editor, and Peňáz, Petr, editor

Published
2020
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21. XR Accessibility – Learning from the Past and Addressing Real User Needs for Inclusive Immersive Environments : Introduction to the Special Thematic Session

Author

O Connor, Joshue, Abou-Zahra, Shadi, Covarrubias Rodriguez, Mario, Aruanno, Beatrice, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Miesenberger, Klaus, editor, Manduchi, Roberto, editor, Covarrubias Rodriguez, Mario, editor, and Peňáz, Petr, editor

Published
2020
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22. Severe asthma: One disease and multiple definitions

Author

Guarnieri, Gabriella, Patella, Vincenzo, Maria Pia, Foschino Barbaro, Carpagnano, Giovanna Elisiana, Colle, Anna del, Scioscia, Giulia, Gerolamo, Pelaia, Puggioni, Francesca, Racca, Francesca, Favero, Elisabetta, Iannacone, Sandra, Savi, Eleonora, Montagni, Marcello, Camiciottoli, Gianna, Allegrini, Chiara, Lombardi, Carlo, Spadaro, Giuseppe, Detoraki, Caterina, Menzella, Francesco, Galeone, Carla, Ruggiero, Patrizia, Yacoub, Monna Rita, Berti, Alvise, Scichilone, Nicola, Durante, Carmen, Costantino, Maria Teresa, Roncallo, Chiara, Braschi, Mariachiara, D’Adda, Alice, Ridolo, Erminia, Triggiani, Massimo, Parente, Roberta, Maria, D’Amato, Verrillo, Maria Vittoria, Rolla, Giovanni, Brussino, Luisa, Frazzetto, Agata Valentina, Cristina, Zappa Maria, Lilli, Marianna, Crimi, Nunzio, Bonavia, Marco, Corsico, Angelo Guido, Grosso, Amelia, Del Giacco, Stefano, Deidda, Margherita, Ricciardi, Luisa, Isola, Stefania, Cicero, Francesca, Amato, Giuliana, Vita, Federica, Spanevello, Antonio, Pignatti, Patrizia, Cherubino, Francesca, Visca, Dina, Massimo Ricciardolo, Fabio Luigi, Anna Carriero, Vitina Maria, Bertolini, Francesca, Santus, Pierachille, Barlassina, Roberta, Airoldi, Andrea, Guida, Giuseppe, Eleonora, Nucera, Aruanno, Arianna, Rizzi, Angela, Caruso, Cristiano, Colantuono, Stefania, Senna, Gianenrico, Caminati, Marco, Arcolaci, Alessandra, Vianello, Andrea, Bianchi, Fulvia Chieco, Marchi, Maria Rita, Centanni, Stefano, Luraschi, Simone, Ruggeri, Silvia, Rinaldo, Rocco, Parazzini, Elena, Calabrese, Cecilia, Flora, Martina, Cosmi, Lorenzo, Di Pietro, Linda, Maggi, Enrico, Pini, Laura, Macchia, Luigi, Di Bona, Danilo, Richeldi, Luca, Condoluci, Carola, Fuso, Leonello, Bonini, Matteo, Farsi, Alessandro, Carli, Giulia, Montuschi, Paolo, Santini, Giuseppe, Conte, Maria Elisabetta, Turchet, Elisa, Barbetta, Carlo, Mazza, Francesco, D’Alo, Simona, Pucci, Stefano, Caiaffa, Maria Filomena, Minenna, Elena, D'Elia, Luciana, Pasculli, Carlo, Viviano, Vittorio, Tarsia, Paolo, Rolo, Joyce, Di Proietto, Mariacarmela, Lo Cicero, Salvatore, Bagnasco, Diego, Paggiaro, Pierluigi, Latorre, Manuela, Folli, Chiara, Testino, Elisa, Bassi, Arianna, Milanese, Manlio, Heffler, Enrico, Manfredi, Andrea, Riccio, Anna Maria, De Ferrari, Laura, Blasi, Francesco, Canevari, Rikki Frank, Canonica, Giorgio Walter, and Passalacqua, Giovanni

Published
2021
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23. A Novel Digitized Method for the Design and Additive Manufacturing of Orthodontic Space Maintainers

Author

Francesco Tamburrino, Andrea Chiocca, Beatrice Aruanno, Alessandro Paoli, Lisa Lardani, Elisabetta Carli, Giacomo Derchi, Maria Rita Giuca, Armando V. Razionale, and Sandro Barone

Subjects
pediatric dentistry, digital space maintainer, generative design, FEA analysis, 3D printing, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
Abstract

Primary dentition is crucial in influencing the emergence of permanent teeth. Premature primary tooth loss can result in undesired tooth motions and space loss in the permanent dentition. Typically, fixed or removable dental appliances are adopted to maintain edentulous space until the eruption of permanent teeth. However, traditional space maintainers have limitations in terms of variability in tooth anatomy, potential allergic reactions in some individuals (i.e., nickel sensitivity), difficulties in maintaining oral hygiene, and patient acceptance. The present study introduces a fully digital framework for the design and manufacturing of customized pediatric unilateral space maintainers using generative algorithms. The proposed approach overcomes the current challenges by using a biocompatible resin material and optimizing the device’s size, design, and color. The methodology involves intraoral scanning, surface selection, and trim, generative 3D modeling, finite element analysis (FEA), and additive manufacturing (AM) through vat photopolymerization. FEA results demonstrate the device’s mechanical performance and reliability, while additive manufacturing ensures design freedom, high resolution, surface finishing, dimensional accuracy, and proper fit. The mechanical interlocking system facilitates easy and effective positioning of the device. This digital approach offers the potential for wider usage of space maintainers and can be further validated through experimental assessments and clinical studies.

Published
2023
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24. Economic impact of mepolizumab in uncontrolled severe eosinophilic asthma, in real life

Author

Guarnieri, Gabriella, Patella, Vincenzo, Maria Pia, Foschino Barbaro, Carpagnano, Elisiana, Colle, Anna del, Scioscia, Giulia, Gerolamo, Pelaia, Paggiaro, Pierluigi, Latorre, Manuela, Puggioni, Francesca, Racca, Francesca, Favero, Elisabetta, Iannacone, Sandra, Savi, Eleonora, Montagni, Marcello, Camiciottoli, Gianna, Allegrini, Chiara, Spadaro, Giuseppe, Detoraki, Caterina, Galeone, Carla, Ruggiero, Patrizia, Yacoub, Monna Rita, Berti, Alvise, Colombo, Gisella, Scichilone, Nicola, Durante, Carmen, Costantino, Maria Teresa, Roncallo, Chiara, Braschi, Mariachiara, Blasi, Francesco, D'Adda, Alice, Ridolo, Erminia, Triggiani, Massimo, Parente, Roberta, Maria, D'Amato, Verrillo, Maria Vittoria, Cristina, Zappa Maria, Lilli, Marianna, Crimi, Nunzio, Bonavia, Marco, Corsico, Angelo Guido, Grosso, Amelia, Del Giacco, Stefano, Deidda, Margherita, Ricciardi, Luisa, Isola, Stefania, Cicero, Francesca, Amato, Giuliana, Vita, Federica, Spanevello, Antonio, Pignatti, Patrizia, Cherubino, Francesca, Visca, Dina, Aletti, Eleonora, Massimo Ricciardolo, Fabio Luigi, Anna Carriero, Vitina Maria, Bertolini, Francesca, Santus, Pierachille, Barlassina, Roberta, Airoldi, Andrea, Guida, Giuseppe, Eleonora, Nucera, Aruanno, Arianna, Rizzi, Angela, Caruso, Cristiano, Colantuono, Stefania, Arcolaci, Alessandra, Vianello, Andrea, Bianchi, Fulvia Chieco, Marchi, Maria Rita, Centanni, Stefano, Luraschi, Simone, Ruggeri, Silvia, Rinaldo, Rocco, Parazzini, Elena, Calabrese, Cecilia, Flora, Martina, Cosmi, Lorenzo, Di Pietro, Linda, Maggi, Enrico, Pini, Laura, Macchia, Luigi, Di Bona, Danilo, Richeldi, Luca, Condoluci, Carola, Fuso, Leonello, Bonini, Matteo, Farsi, Alessandro, Carli, Giulia, Montuschi, Paolo, Santini, Giuseppe, Conte, Maria Elisabetta, Turchet, Elisa, Barbetta, Carlo, Mazza, Francesco, D'Alo, Simona, Pucci, Stefano, Caiaffa, Maria Filomena, Minenna, Elena, D'Elia, Luciana, Pasculli, Carlo, Viviano, Vittorio, Tarsia, Paolo, Rolo, Joyce, Di Proietto, Mariacarmela, Lo Cicero, Salvatore, Bagnasco, Diego, Povero, Massimiliano, Pradelli, Lorenzo, Brussino, Luisa, Rolla, Giovanni, Caminati, Marco, Menzella, Francesco, Heffler, Enrico, Canonica, Giorgio Walter, Senna, Gianenrico, Milanese, Manlio, Lombardi, Carlo, Bucca, Caterina, Manfredi, Andrea, Canevari, Rikki Frank, and Passalacqua, Giovanni

Published
2021
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25. Enhancing Inclusive Education for Young Students with Special Needs through Mixed Reality: Exploring the Potential of CNC Milling Machine Application

Author

Aruanno, B., Carruba, Maria Concetta, Mondellini, Marta, Santos-Paz, J. A., Ferrise, F., Karaki, J., Covarrubias, M., Carruba M. C. (ORCID:0000-0001-9316-6509), Mondellini M. (ORCID:0000-0002-9578-4586), Aruanno, B., Carruba, Maria Concetta, Mondellini, Marta, Santos-Paz, J. A., Ferrise, F., Karaki, J., Covarrubias, M., Carruba M. C. (ORCID:0000-0001-9316-6509), and Mondellini M. (ORCID:0000-0002-9578-4586)

Abstract

Mixed Reality (MR) is one of the major technology trends right now, and it is going to increase much more in the future. This term includes different technologies that range from Augmented Reality (AR) to immersive Virtual Reality (VR). The main characteristic of AR is the possibility to see and interact with virtual objects while always being able to see the surrounding real world thanks to a dedicated device. This technology allows a new way of interaction, communication, and productivity. The aim of this paper is the development of an MR application for the Charly4U CNC milling machine that helps students with special needs to work and interact with the machine safely. Three configurations have been developed and tested: a desktop version running on a PC, an Android tablet-based version, and a solution running on the Microsoft HoloLens device.

Published
2024

26. Mollusk allergy in shrimp-allergic patients: Still a complex diagnosis. An Italian real-life cross-sectional multicenter study

Author

Enrico Scala, MD, Damiano Abeni, MD, Arianna Aruanno, MD, Elisa Boni, MD, Ignazio Brusca, MD, Francesca Cappiello, MD, Elisabetta Caprini, BD, Francesca Buzzulini, MD, Gaia Deleonardi, MD, Antongiulio Demonte, MD, Laura Farioli, MD, Fabio Lodi Rizzini, MD, Laura Michelina Losappio, MD, Donatella Macchia, MD, Giuseppina Manzotti, MD, Giorgia Meneguzzi, MD, Marcello Montagni, MD, Eleonora Nucera, MD, Rosa Onida, MD, Elide Anna Pastorello, MD, Silvia Peveri, MD, Anna Radice, MD, Federica Rivolta, MD, Angela Rizzi, MD, Mauro Giani, MD, Lorenzo Cecchi, MD, Elena Pinter, MD, Marzia Miglionico, MD, Lorenzo Vantaggio, MD, Valerio Pravettoni, MD, Danilo Villalta, MD, and Riccardo Asero, MD

Subjects
Multiplex analysis, IgE diagnosis, Tropomyosin, Crustaceans, Mollusks, Food allergy, Immunologic diseases. Allergy, RC581-607
Abstract

Introduction: Shellfish allergy is an important cause of food allergies worldwide. Both in vivo and in vitro diagnostics failure nowadays is caused by the poor quality of the extracts associated with the scarce availability of allergenic molecules in the market. It is known that not all patients with shellfish allergies experience adverse reactions to mollusks. It is still unclear how to detect and diagnose these patients correctly. Aim: To investigate the features of shrimp-allergic patients either reactive or tolerant to mollusks, with the currently available diagnostic methods. Methods: Nineteen centers, scattered throughout Italy, participated in the real-life study, enrolling patients allergic to shrimp with or without associated reactions to mollusks. Patients underwent skin tests using commercial extracts or fresh raw and cooked shrimp and mollusks, and IgE reactivity to currently available allergenic extracts and molecules was measured in vitro. Results: Two hundred and forty-seven individuals with a self reported adverse reactions to shrimp participated in the study; of these 47.8% reported an adverse reaction to mollusks ingestion (cephalopod and/or bivalve). Neither of the tests used, in vivo nor in vitro, was able to detect all selected patients. Accordingly, a great heterogeneity of results was observed: in vivo and in vitro tests agreed in 52% and 62% of cases. Skin tests were able to identify the mollusk reactors (p

Published
2022
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27. Anaphylaxis after SonoVue: A Case Report and a Literature Review.

Author

Longhino, David, Buonomo, Alessandro, Zocco, Maria Assunta, Ainora, Maria Elena, Esposto, Giorgio, Mignini, Irene, Cerrito, Lucia, Ponziani, Francesca Romana, Gasbarrini, Antonio, Nucera, Eleonora, and Aruanno, Arianna

Subjects
LITERATURE reviews, SIGNAL-to-noise ratio, ANAPHYLAXIS, DRUG utilization, ULTRASONIC imaging
Abstract

SonoVue (Bracco, Milan, Italy) is a drug used in ultrasonography for the purpose of increasing the echogenicity of blood or fluids by improving the signal-to-noise ratio. Background/Objectives/Methods: We described a case of anaphylaxis due to SonoVue and performed a literature review. Results and Conclusions: We reported a case of anaphylaxis secondary to the administration of SonoVue and described all the 13 literature cases. Given its widespread use and the potentially dangerous nature of the reactions it can cause, it is advisable to know how to promptly recognize fatal reactions. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Mollusk allergy in shrimp-allergic patients: still a complex diagnosis. An Italian multicenter study

Author

Scala, Enrico, primary, A, Aruanno, additional, Elisa, Boni, additional, Brusca, Ignazio, additional, Francesca, Cappiello, additional, Elisabetta, Caprini, additional, Buzzulini, Francesca, additional, Deleonardi, Gaia, additional, A, Demonte, additional, Farioli, Laura, additional, Lodi-Rizzini, Fabio, additional, Losappio, Laura, additional, Macchia, Donatella, additional, Manzotti, Giuseppina, additional, Giorgia, Meneguzzi, additional, Marcello, Montagni, additional, Nucera, Eleonora, additional, Rosa, Onida, additional, Pastorello, Elide Anna, additional, peveri, silvia, additional, Radice, Anna, additional, Rivolta, Federica, additional, Rizzi, Angela, additional, Giani, Mauro, additional, Cecchi, Lorenzo, additional, E, Pinter, additional, Marzia, Miglionico, additional, L, Vantaggio, additional, V, Pravettoni, additional, Villalta, Danilo, additional, and Asero, Riccardo, additional

Published
2024
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33. Adult-onset atopic dermatitis induced by vedolizumab: a case series.

Author

Nucera, Eleonora, Urbani, Sara, Aruanno, Arianna, Scaldaferri, Franco, D'Urso, Dario, and De Simone, Clara

Subjects
CROHN'S disease, DRUG eruptions, RESPIRATORY infections, ERYTHEMA nodosum, FAMILY history (Medicine), ECZEMA, ATOPY
Abstract

The document discusses a case series where four patients developed adult-onset atopic dermatitis after starting therapy with vedolizumab, a medication used to treat ulcerative colitis and Crohn's disease. The patients had no prior history of atopic dermatitis and underwent various tests to confirm the diagnosis. Despite the skin reactions, the therapy was not discontinued, and patients were treated with topical therapies. Further research is needed to understand the mechanism behind the development of atopic dermatitis during vedolizumab therapy. [Extracted from the article]

Published
2024
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34. The role of skin tests with polyethylene glycol and polysorbate 80 in the vaccination campaign for COVID-19: results from an Italian multicenter survey

Author

Montera, M C, Giordano, A, Asperti, C, Aruanno, Arianna, Barzaghi, C E, Bignardi, D, Borrelli, P, Bommarito, L, Busa, Mattia Fernando, Calafiore, P, Carusi, V, Cinquini, M, Cortellini, G, Cocchi, Riccardo, D'Auria, F, De Caro, F, Demonte, A, Di Leo, E, Di Lizia, M, Di Rienzo, A, Fumagalli, Francesca, Kihlgren, P, Lodi Rizzini, F, Macchia, D, Manzotti, G, Marra, A M, Mileto, P, Mietta, S, Montagni, M, Nettis, E, Nucera, Eleonora, Peveri, S, Pivetta, D, Pirisi, M, Ramirez, G A, Rivolta, F, Rizzi, Angela, Savoia, Andrea Alessio, Pedicini, A, Scarpa, A, Zisa, G, Yacoub, M-R, Aruanno, A, Busa, M, Cocchi, R, Fumagalli, F, Nucera, E (ORCID:0000-0002-0565-7680), Rizzi, A (ORCID:0000-0002-6795-746X), Savoia, A, Montera, M C, Giordano, A, Asperti, C, Aruanno, Arianna, Barzaghi, C E, Bignardi, D, Borrelli, P, Bommarito, L, Busa, Mattia Fernando, Calafiore, P, Carusi, V, Cinquini, M, Cortellini, G, Cocchi, Riccardo, D'Auria, F, De Caro, F, Demonte, A, Di Leo, E, Di Lizia, M, Di Rienzo, A, Fumagalli, Francesca, Kihlgren, P, Lodi Rizzini, F, Macchia, D, Manzotti, G, Marra, A M, Mileto, P, Mietta, S, Montagni, M, Nettis, E, Nucera, Eleonora, Peveri, S, Pivetta, D, Pirisi, M, Ramirez, G A, Rivolta, F, Rizzi, Angela, Savoia, Andrea Alessio, Pedicini, A, Scarpa, A, Zisa, G, Yacoub, M-R, Aruanno, A, Busa, M, Cocchi, R, Fumagalli, F, Nucera, E (ORCID:0000-0002-0565-7680), Rizzi, A (ORCID:0000-0002-6795-746X), and Savoia, A

Abstract

Background. International guidelines suggested skin tests with Polyethylene-glycol (PEG) and polysorbate 80 (PS-80), to investigate a possible hypersensitivity to these excipients either to identify subjects at risk of developing allergic reactions to Covid-19 vaccines, or in patients with suspected IgE mediated hypersensitivity reactions (HR) to the Covid-19 vaccine. The main purpose of this study was to investigate the prevalence of PEG and PS sensitization in patients with a clinical history of HR to drugs containing PEG/PS and in patients with a suspected Covid-19 vaccine immediate HR. Methods. This was a multicenter retrospective study conducted by allergists belonging to 20 Italian medical centers. Skin testing was performed in 531 patients with either a clinical history of suspected hypersensitivity reaction (HR) to drugs containing PEG and/or PS-80 (group 1:362 patient) or a suspected HR to Covid-19 vaccines (group 2: 169 patient), as suggested by the AAIITO/SIAAIC guidelines for the "management of patients at risk of allergic reactions to Covid-19 vaccines" [1]. Results. 10/362 (0.02%) had positive skin test to one or both excipients in group 1, 12/169 (7.1%) in group 2 (p less than 0.01). In group 2 HRs to Covid-19 vaccines were immediate in 10/12 of cases and anaphylaxis occurred in 4/12 of patients. Conclusions. The positivity of skin test with PEG and or PS before vaccination is extremely rare and mostly replaceable by an accurate clinical history. Sensitization to PEG and PS has to be investigated in patients with a previous immediate HR to a Covid-19 vaccine, in particular in patients with anaphylaxis.

Published
2023

37. Design of a Low-Cost Exoskeleton for Hand Tele-Rehabilitation After Stroke

Author

Candeo, Riccardo, Rossini, Mauro, Aruanno, Beatrice, Covarrubias, Mario, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Pandu Rangan, C., Editorial Board Member, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Miesenberger, Klaus, editor, and Kouroupetroglou, Georgios, editor

Published
2018
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40. A Modified Basophil Activation Test for the Clinical Management of Immediate Hypersensitivity Reactions to Paclitaxel: A Proof-of-Concept Study

Author

La Sorda, Marilena, primary, Fossati, Marco, additional, Graffeo, Rosalia, additional, Ferraironi, Manuela, additional, De Rosa, Maria Cristina, additional, Buzzonetti, Alexia, additional, Righino, Benedetta, additional, Zampetti, Nicole, additional, Fattorossi, Andrea, additional, Nucera, Eleonora, additional, Aruanno, Arianna, additional, Ferrandina, Gabriella, additional, Apostol, Adriana Ionelia, additional, Buonomo, Alessandro, additional, Scambia, Giovanni, additional, Sanguinetti, Maurizio, additional, and Battaglia, Alessandra, additional

Published
2023
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47. Clinical and quality of life assessment in patients with latex allergy during COVID-19 pandemic: Possible protective role of continuous latex immunotherapy

Author

Di Rienzo, A, Urbani, Sara, Longhino, David, Sarnari, Caterina, Buonomo, Alessandro, Rizzi, Angela, Aruanno, Arianna, Nucera, Eleonora, Urbani, S, Longhino, D, Sarnari, C, Buonomo, A, Rizzi, A (ORCID:0000-0002-6795-746X), Aruanno, A, Nucera, E (ORCID:0000-0002-0565-7680), Di Rienzo, A, Urbani, Sara, Longhino, David, Sarnari, Caterina, Buonomo, Alessandro, Rizzi, Angela, Aruanno, Arianna, Nucera, Eleonora, Urbani, S, Longhino, D, Sarnari, C, Buonomo, A, Rizzi, A (ORCID:0000-0002-6795-746X), Aruanno, A, and Nucera, E (ORCID:0000-0002-0565-7680)

Abstract

Introduction: During COVID-19 pandemic, the massive use of Personal Protective Equipment could provoke severe adverse reactions in latex allergy patients and could negatively affect their quality of life. Methods: Trough a survey the study aimed: (a) to evaluate the incidence of allergic reactions in patients with latex allergy during the SARS-CoV-2 pandemic; (b) to evaluate the protective role of continuous latex sublingual immunotherapy (SLIT) during this period; and (c) to evaluate quality of life of natural rubber latex allergy (NRLA) patients during the pandemic. Results: 67 patients (9 males and 58 females, mean age of 45.9 +/- 11.4 years) suffering from latex allergy were included in the present study. We recorded among our patients 13 cases (34.2%) of urticarial/angioedema (U/A), 9 cases (23.6%) of respiratory symptoms (dyspnoea, shortness of breath and wheezing) and 7 cases (18.4%) of anaphylaxis. In patients who underwent continuous SLIT, we observed less cases of U/A (p < 0.001), respiratory symptoms (p < 0.001), anaphylaxis (p = 0.003), hospitalizations (p = 0.014) and a lower therapy administration. We compared the results of SF-36 questionnaire in patients who underwent continuous and not-continuous SLIT with a significance differences score between these two groups. Conclusions: Our study is the first that investigated the clinical and quality of life effects of COVID-19 pandemic in NRLA patients.

Published
2022

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