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1. Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study: protocol of a pragmatic clinical effectiveness study to improve birth outcomes in Ethiopia

Author

Alemayehu Worku, Sheila Isanaka, Yemane Berhane, Chunling Lu, Grace J Chan, Luke C Mullany, Blair J Wylie, Michelle Eglovitch, Anne CC Lee, Parul Christian, Estifanos Baye, Firehiwot Workneh Abate, Yoseph Yemane Berhane, Mulatu Melese Derebe, Nebiyou Fasil, Ingrid E Olson, Workagegnehu Tarekegn Kidane, Tigest Shiferaw, Fisseha Shiferie, Fitsum Tsegaye, Sitota Tsegaye, Kalkidan Yibeltal, Yunhee Kang, Mandefro M Mengistie, Rose L. Molina, Michele D Stojanov, Fred Van Dyk, Amare Worku Tadesse, and Asresie T Wondale

Subjects
Pediatrics, RJ1-570
Abstract

Introduction The WHO Nutrition Target aims to reduce the global prevalence of low birth weight by 30% by the year 2025. The Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study will test the impact of packages of pregnancy interventions to enhance maternal nutrition and infection management on birth outcomes in rural Ethiopia.Methods and analysis ENAT is a pragmatic, open-label, 2×2 factorial, randomised clinical effectiveness study implemented in 12 rural health centres in Amhara, Ethiopia. Eligible pregnant women presenting at antenatal care (ANC) visits at

Published
2022
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2. Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study: protocol of a pragmatic clinical effectiveness study to improve birth outcomes in Ethiopia

Author

Anne CC Lee, Firehiwot Workneh Abate, Luke C Mullany, Estifanos Baye, Yoseph Yemane Berhane, Mulatu Melese Derebe, Michelle Eglovitch, Nebiyou Fasil, Ingrid E Olson, Workagegnehu Tarekegn Kidane, Tigest Shiferaw, Fisseha Shiferie, Fitsum Tsegaye, Sitota Tsegaye, Kalkidan Yibeltal, Grace J Chan, Parul Christian, Sheila Isanaka, Yunhee Kang, Chunling Lu, Mandefro M Mengistie, Rose L. Molina, Michele D Stojanov, Fred Van Dyk, Amare Worku Tadesse, Asresie T Wondale, Blair J Wylie, Alemayehu Worku, and Yemane Berhane

Subjects
Iron, growth, Infant, Newborn, Parturition, Infant, Infant, Low Birth Weight, Pediatrics, neonatology, RJ1-570, Folic Acid, Treatment Outcome, Pregnancy, Pragmatic Clinical Trials as Topic, Pediatrics, Perinatology and Child Health, Protocol, Humans, Premature Birth, Female, Ethiopia, Randomized Controlled Trials as Topic
Abstract

IntroductionThe WHO Nutrition Target aims to reduce the global prevalence of low birth weight by 30% by the year 2025. The Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study will test the impact of packages of pregnancy interventions to enhance maternal nutrition and infection management on birth outcomes in rural Ethiopia.Methods and analysisENAT is a pragmatic, open-label, 2×2 factorial, randomised clinical effectiveness study implemented in 12 rural health centres in Amhara, Ethiopia. Eligible pregnant women presenting at antenatal care (ANC) visits at Ethics and disseminationENAT is approved by the Institutional Review Boards of Addis Continental Institute of Public Health (001-A1-2019) and Mass General Brigham (2018P002479). Results will be disseminated to local and international stakeholders.Registration numberISRCTN15116516.

Published
2022

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