Search

Your search keyword '"Athanassopoulos C"' showing total 46 results
Start Over Author "Athanassopoulos C"
46 results on '"Athanassopoulos C"'

1. Evidence for nu_mu -> nu_e Neutrino Oscillations from LSND

Author

LSND Collaboration, Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Caldwell, D. O., Church, E. D., Cohen, I., Donahue, J. B., Fazely, A., Federspiel, F. J., Garvey, G. T., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., White, D. H., Works, D., Xiao, Y., and Yellin, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

A search for nu_mu -> nu_e oscillations has been conducted with the LSND apparatus at the Los Alamos Meson Physics Facility. Using nu_mu from pi^+ decay in flight, the nu_e appearance is detected via the charged-current reaction C(nu_e,e^-)X. Two independent analyses observe a total of 40 beam-on high-energy electron events (60 < E_e < 200 MeV) consistent with the above signature. This number is significantly above the 21.9 +- 2.1 events expected from the nu_e contamination in the beam and the beam-off background. If interpreted as an oscillation signal, the observed oscillation probability of (2.6 +- 1.0 +- 0.5) x 10^{-3} is consistent with the previously reported nu_mu_bar -> nu_e_bar oscillation evidence from LSND., Comment: 10 pages (LaTeX), 3 figures (PostScript), submitted to Phys.Rev.Lett. Additional information at http://nu1.lampf.lanl.gov/~lsnd

Published
1997
Full Text
View/download PDF

2. Evidence for nu_mu -> nu_e Oscillations from Pion Decay in Flight Neutrinos

Author

LSND Collaboration, Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Caldwell, D. O., Church, E. D., Cohen, I., Dieterle, B. D., Donahue, J. B., Fazely, A., Federspiel, F. J., Garvey, G. T., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., Margulies, J., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., White, D. H., Works, D., Xiao, Y., and Yellin, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

A search for nu_mu -> nu_e oscillations has been conducted at the Los Alamos Meson Physics Facility using nu_mu from pi^+ decay in flight. An excess in the number of beam-related events from the C(nu_e,e^-)X inclusive reaction is observed. The excess is too large to be explained by normal nu_e contamination in the beam at a confidence level greater than 99%. If interpreted as an oscillation signal, the observed oscillation probability of (2.6 +- 1.0 +- 0.5) x 10^{-3} is consistent with the previously reported nu_mu_bar -> nu_e_bar oscillation evidence from LSND., Comment: 70 pages (LaTeX), 32 figures (PostScript), submitted to Phys. Rev. C. Additional information at http://nu1.lampf.lanl.gov/~lsnd

Published
1997
Full Text
View/download PDF

3. Measurements of the reactions 12C + nu_e -> e- + 12N g.s. and 12C + nu_e -> e- + 12N

Author

Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Cohen, I., Caldwell, D. O., Dieterle, B. D., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., Margulies, J., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., Wang, Y-X., White, D. H., Works, D., Xiao, Y., and Yellin, S.

Subjects
Nuclear Experiment
Abstract

Charged current reactions of nu_e on 12C have been studied using a mu decay-at-rest nu_e beam from the Los Alamos Meson Physics Facility. More than 500 events from the exclusive reaction 12C + nu_e -> e- + 12N g.s. were measured in a large Liquid Scintillator Neutrino Detector (LSND). The observed energy dependence of the cross section and the angular distribution of the outgoing electron agree well with theoretical expectations. Measurements are also presented for inclusive transitions to 12N excited states, 12C + nu_e -> e- + 12N and compared with theoretical expectations. Results are consistent with a recent Continuum Random Phase Approximation (CRPA) calculation., Comment: Figures included with psfig

Published
1997
Full Text
View/download PDF

4. Measurements of the reactions 12C + nu_mue -> mu- + 12N g.s. and 12C + nu_mu -> mue- + 12N

Author

Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Cohen, I., Caldwell, D. O., Dieterle, B. D., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., Margulies, J., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., Wang, Y-X., White, D. H., Works, D., Xiao, Y., and Yellin, S.

Subjects
Nuclear Experiment
Abstract

Charged current scattering of nu_mu on 12C has been studied using a pi+ decay-in-flight nu_mu beam at the Los Alamos Meson Physics Facility. A sample of 56.8 +- 9.6 events satisfying criteria for the exclusive reaction 12C + nu_mu -> mu- + 12N_g.s. was obtained using the large Liquid Scintillator Neutrino Detector (LSND). The observed flux-averaged cross section, (6.6 +- 1.0 +- 1.0) x 10^-41 cm^2, agrees well with reliable theoretical expectations. A measurement was also obtained for the inclusive cross section to all accessible 12N states, 12C + nu_\mu -> mu- + X. This flux-averaged cross section is (11.2 +- 0.3 +- 1.8)x 10^-40 cm^2, which is approximately half of that given by a recent Continuum Random Phase Approximation (CRPA) calculation., Comment: Figures included with psfig

Published
1997
Full Text
View/download PDF

5. Evidence for $\bar\nu_\mu\to\bar\nu_e$ Oscillations from the LSND Experiment at LAMPF

Author

Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Cohen, I., Caldwell, D. O., Dieterle, B. D., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., Margulies, J., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., Wang, Y-X., White, D. H., Works, D., Xiao, Y., Yellin, S., and Collaboration, LSND

Subjects
Nuclear Experiment, High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Theory
Abstract

A search for $\bar\nu_{\mu}\to \bar\nu_{e}$ oscillations has been conducted at the Los Alamos Meson Physics Facility by using $\bar\nu_\mu$ from $\mu^+$ decay at rest. The $\bar\nu_e$ are detected via the reaction $\bar\nu_e\,p \rightarrow e^{+}\,n$, correlated with a $\gamma$ from $np\rightarrow d\gamma$ ($2.2\,{\rm MeV}$). The use of tight cuts to identify $e^+$ events with correlated $\gamma$ rays yields 22 events with $e^+$ energy between 36 and $60\,{\rm MeV}$ and only $4.6 \pm 0.6$ background events. A fit to the $e^+$ events between 20 and $60\,{\rm MeV}$ yields a total excess of $51.8^{+18.7}_{-16.9} \pm 8.0$ events. If attributed to $\bar \nu_\mu \rightarrow \bar \nu_e$ oscillations, this corresponds to an oscillation probability of ($0.31^{+0.11}_{-0.10} \pm 0.05$)\%., Comment: 4 pages, 3 figures, revtex, psfig. additional information available at http://nu1.lampf.lanl.gov/~lsnd/

Published
1996
Full Text
View/download PDF

6. The Liquid Scintillator Neutrino Detector and LAMPF Neutrino Source

Author

Athanassopoulos, C., Auerbach, L. B., Bauer, D., Bolton, R. D., Burman, R. L., Cohen, I., Caldwell, D. O., Dieterle, B. D., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Highland, V., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Lu, A., Margulies, J., Mills, G. B., McIlhany, K., Metcalf, W., Reeder, R. A., Sandberg, V., Schillaci, M., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wang, Y-X., White, D. H., Whitehouse, D., Works, D., Xiao, Y., and Yellin, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

A search for neutrino oscillations of the type nu_bar_mu to nu_bar_e has been conducted at the Los Alamos Meson Physics Facility using nu_bar_mu from muon decay at rest. Evidence for this transition has been reported previously. This paper discusses in detail the experimental setup, detector operation and neutrino source, including aspects relevant to oscillation searches in the muon decay-at-rest and pion decay in flight channels., Comment: 27 pages, 26 figures, revtex and psfig, additional information available at http://nu1.lampf.lanl.gov/~lsnd/

Published
1996
Full Text
View/download PDF

7. Evidence for Neutrino Oscillations from Muon Decay at Rest

Author

Athanassopoulos, C., Auerbach, L. B., Burman, R. L., Cohen, I., Caldwell, D. O., Dieterle, B. D., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Imlay, R., Johnston, K., Kim, H. J., Louis, W. C., Majkic, R., Margulies, J., McIlhany, K., Metcalf, W., Mills, G. B., Reeder, R. A., Sandberg, V., Smith, D., Stancu, I., Strossman, W., Tayloe, R., VanDalen, G. J., Vernon, W., Wadia, N., Waltz, J., Wang, Y-X., White, D. H., Works, D., Xiao, Y., and Collaboration, S. Yellin The LSND

Subjects
Nuclear Experiment, High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Theory
Abstract

A search for nu_bar_mu to nu_bar_e oscillations has been conducted at the Los Alamos Meson Physics Facility using nu_bar_mu from mu+ decay at rest. The nu_bar_e are detected via the reaction (nu_bar_e,p) -> (e+,n), correlated with the 2.2 MeV gamma from (n,p) -> (d,gamma). The use of tight cuts to identify e+ events with correlated gamma rays yields 22 events with e+ energy between 36 and 60 MeV and only 4.6 (+/- 0.6) background events. The probability that this excess is due entirely to a statistical fluctuation is 4.1E-08. A chi^2 fit to the entire e+ sample results in a total excess of 51.8 (+18.7) (-16.9) (+/- 8.0) events with e+ energy between 20 and 60 MeV. If attributed to nu_bar_mu -> nu_bar_e oscillations, this corresponds to an oscillation probability (averaged over the experimental energy and spatial acceptance) of 0.0031 (+0.0011) (-0.0010) (+/- 0.0005)., Comment: 57 pages, 34 figures, revtex, additional information available at http://nu1.lampf.lanl.gov/~lsnd/

Published
1996
Full Text
View/download PDF

8. Candidate Events in a Search for Muon Antineutrino to Electron Antineutrino Oscillations

Author

Athanassopoulos, C., Auerbach, L. B., Bolton, R., Boyd, B., Burman, R. L., Caldwell, D. O., Cohen, I., Donahue, J. B., Eisner, A. M., Fazely, A., Federspiel, F. J., Garvey, G. T., Gray, M., Gunasingha, R. M., Highland, V., Imlay, R., Johnston, K., Louis, W. C., Lu, A., Margulies, J., McIlhany, K., Metcalf, W., Reeder, R. A., Sandberg, V., Schillaci, M., Smith, D., Stancu, I., Strossman, W., VanDalen, G. J., Vernon, W., Wang, Y-X., White, D. H., Whitehouse, D., Works, D., and Xiao, Y.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Theory
Abstract

A search for $\nuebar$'s in excess of the number expected from conventional sources has been made using the Liquid Scintillator Neutrino Detector, located 30 m from a proton beam dump at LAMPF. A $\nuebar$ signal was detected via the reaction $\nuebar\,p \rightarrow e^{+}\,n$ with $e^+$ energy between 36 and $60\mev$, followed by a $\gamma$ from $np\rightarrow d\gamma$ ($2.2\mev$). Using strict cuts to identify $\gamma$'s correlated with positrons results in a signal of 9 events, with an expected background of $2.1 \pm 0.3$. A likelihood fit to the entire $e^+$ sample yields a total excess of $16.4^{+9.7}_{-8.9}\pm 3.3$ events, where the second uncertainty is systematic. If this excess is attributed to neutrino oscillations of the type $\numubar\rightarrow\nuebar$, it corresponds to an oscillation probability of ($0.34^{+0.20}_{-0.18}\pm 0.07$)\%., Comment: 3 PS figures; corrected TeX file (April 21, 1995)

Published
1995
Full Text
View/download PDF

9. Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells

Author

Pediconi, N., Ghirga, F., Del Plato, C., Peruzzi, G., Athanassopoulos, C. M., Mori, M., Crestoni, M. E., Corinti, D., Ugozzoli, F., Massera, C., Arcovito, Alessandro, Botta, B., Boffi, A., Quaglio, D., Baiocco, P., Arcovito A. (ORCID:0000-0002-8384-4844), Pediconi, N., Ghirga, F., Del Plato, C., Peruzzi, G., Athanassopoulos, C. M., Mori, M., Crestoni, M. E., Corinti, D., Ugozzoli, F., Massera, C., Arcovito, Alessandro, Botta, B., Boffi, A., Quaglio, D., Baiocco, P., and Arcovito A. (ORCID:0000-0002-8384-4844)

Abstract

Gene expression regulation by small interfering RNA (siRNA) holds promise in treating a wide range of diseases through selective gene silencing. However, successful clinical application of nucleic acid-based therapy requires novel delivery options. Herein, to achieve efficient delivery of negatively charged siRNA duplexes, the internal cavity of "humanized"chimeric Archaeal ferritin (HumAfFt) was specifically decorated with novel cationic piperazine-based compounds (PAs). By coupling these rigid-rod-like amines with thiol-reactive reagents, chemoselective conjugation was efficiently afforded on topologically selected cysteine residues properly located inside HumAfFt. The capability of PAs-HumAfFt to host and deliver siRNA molecules through human transferrin receptor (TfR1), overexpressed in many cancer cells, was explored. These systems allowed siRNA delivery into HeLa, HepG2, and MCF-7 cancer cells with improved silencing effect on glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene expression with respect to traditional transfection methodologies and provided a promising TfR1-targeting system for multifunctional siRNA delivery to therapeutic applications.

Published
2021

13. A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells

Author

Ricci, F., primary, Carrassa, L., additional, Christodoulou, M. S., additional, Passarella, D., additional, Michel, B., additional, Benhida, R., additional, Martinet, N., additional, Hunyadi, A., additional, Ioannou, E., additional, Roussis, V., additional, Musso, L., additional, Dallavalle, S., additional, Silvestri, R., additional, Westwood, N., additional, Mori, M., additional, Ingallina, C., additional, Botta, B., additional, Kavetsou, E., additional, Detsi, A., additional, Majer, Z., additional, Hudecz, F., additional, Bosze, S., additional, Kaminska, B., additional, Hansen, T.V., additional, Bertrand, P., additional, Athanassopoulos, C. M., additional, and Damia, G., additional

Published
2018
Full Text
View/download PDF

16. (2E,4E,6E)-3-Methyl-7-(pyren-1-yl)octa-2,4,6-trienoic acid

Author

Bariamis, S. E., Magoulas, G. E., Athanassopoulos, C. M., Papaioannou, D., Manos, M. J., and Nastopoulos, V.

Abstract

The title compound, C25H20O2, was synthesized by a Wittig reaction between triphenyl[1-(pyren-1-yl)ethyl]phosphonium bromide and ethyl (2E,4E)-3-methyl-6-oxohexa-2,4-dienoate, in the presence of n-butyl lithium, followed by saponification. It was obtained pure in the all-trans configuration following crystallization from ethyl acetate. The asymmetric unit contains two independent molecules (A and B), which are arranged almost parallel to each other within the crystal structure. The triene chain is not coplanar with the pyrene ring system, forming dihedral angles of 52.8 (1) and 42.2 (1)degrees for molecules A and B, respectively. Intermolecular hydrogen bonds between the carboxyl groups of the molecules link them into centrosymmetric pairs, AA and BB, each with the R-2(2)(8) graph-set motif. Acta Crystallographica Section E-Structure Reports Online

Published
2009

22. Results onνμ→νeoscillations from pion decay in flight neutrinos

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Burman, R. L., additional, Caldwell, D. O., additional, Church, E. D., additional, Cohen, I., additional, Donahue, J. B., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gunasingha, R. M., additional, Imlay, R., additional, Johnston, K., additional, Kim, H. J., additional, Louis, W. C., additional, Majkic, R., additional, McIlhany, K., additional, Metcalf, W., additional, Mills, G. B., additional, Reeder, R. A., additional, Sandberg, V., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Tayloe, R., additional, VanDalen, G. J., additional, Vernon, W., additional, Wadia, N., additional, Waltz, J., additional, White, D. H., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1998
Full Text
View/download PDF

23. Results onνμ→νeNeutrino Oscillations from the LSND Experiment

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Burman, R. L., additional, Caldwell, D. O., additional, Church, E. D., additional, Cohen, I., additional, Donahue, J. B., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gunasingha, R. M., additional, Imlay, R., additional, Johnston, K., additional, Kim, H. J., additional, Louis, W. C., additional, Majkic, R., additional, McIlhany, K., additional, Mills, G. B., additional, Reeder, R. A., additional, Sandberg, V., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Tayloe, R., additional, VanDalen, G. J., additional, Vernon, W., additional, Wadia, N., additional, Waltz, J., additional, White, D. H., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1998
Full Text
View/download PDF

25. Measurements of the reactions12C(νμ,μ−)12Ng.s.and12C(νμ,μ−)X

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Burman, R. L., additional, Caldwell, D. O., additional, Church, E., additional, Cohen, I., additional, Dieterle, B. D., additional, Donahue, J. B., additional, Eisner, A. M., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gray, M., additional, Gunasingha, R. M., additional, Imlay, R., additional, Johnston, K., additional, Kim, H. J., additional, Louis, W. C., additional, Majkic, R., additional, McIlhany, K., additional, Metcalf, W., additional, Mills, G. B., additional, Reeder, R. A., additional, Sandberg, V., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Tayloe, R., additional, VanDalen, G. J., additional, Vernon, W., additional, Wadia, N., additional, Waltz, J., additional, Wang, Y-X., additional, White, D. H., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1997
Full Text
View/download PDF

26. The liquid scintillator neutrino detector and LAMPF neutrino source

Author

Athanassopoulos, C, primary, Auerbach, L.B, additional, Bauer, D, additional, Bolton, R.D, additional, Burman, R.L, additional, Cohen, I, additional, Caldwell, D.O, additional, Dieterle, B.D, additional, Donahue, J.B, additional, Eisner, A.M, additional, Fazely, A, additional, Federspiel, F.J, additional, Garvey, G.T, additional, Gray, M, additional, Gunasingha, R.M, additional, Highland, V, additional, Imlay, R, additional, Johnston, K, additional, Kim, H.J, additional, Louis, W.C, additional, Lu, A, additional, Margulies, J, additional, Mills, G.B, additional, McIlhany, K, additional, Metcalf, W, additional, Reeder, R.A, additional, Sandberg, V, additional, Schillaci, M, additional, Smith, D, additional, Stancu, I, additional, Strossman, W, additional, Tayloe, R, additional, VanDalen, G.J, additional, Vernon, W, additional, Wang, Y.-X, additional, White, D.H, additional, Whitehouse, D, additional, Works, D, additional, Xiao, Y, additional, and Yellin, S, additional

Published
1997
Full Text
View/download PDF

27. Evidence for neutrino oscillations from muon decay at rest

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Burman, R. L., additional, Cohen, I., additional, Caldwell, D. O., additional, Dieterle, B. D., additional, Donahue, J. B., additional, Eisner, A. M., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gray, M., additional, Gunasingha, R. M., additional, Imlay, R., additional, Johnston, K., additional, Kim, H. J., additional, Louis, W. C., additional, Majkic, R., additional, Margulies, J., additional, McIlhany, K., additional, Metcalf, W., additional, Mills, G. B., additional, Reeder, R. A., additional, Sandberg, V., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Tayloe, R., additional, VanDalen, G. J., additional, Vernon, W., additional, Wadia, N., additional, Waltz, J., additional, Wang, Y-X., additional, White, D. H., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1996
Full Text
View/download PDF

28. Evidence forν¯μ→ν¯eOscillations from the LSND Experiment at the Los Alamos Meson Physics Facility

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Burman, R. L., additional, Cohen, I., additional, Caldwell, D. O., additional, Dieterle, B. D., additional, Donahue, J. B., additional, Eisner, A. M., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gray, M., additional, Gunasingha, R. M., additional, Imlay, R., additional, Johnston, K., additional, Kim, H. J., additional, Louis, W. C., additional, Majkic, R., additional, Margulies, J., additional, McIlhany, K., additional, Metcalf, W., additional, Mills, G. B., additional, Reeder, R. A., additional, Sandberg, V., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Tayloe, R., additional, VanDalen, G. J., additional, Vernon, W., additional, Wadia, N., additional, Waltz, J., additional, Wang, Y-X., additional, White, D. H., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1996
Full Text
View/download PDF

30. Candidate Events in a Search forν¯μ→ν¯eOscillations

Author

Athanassopoulos, C., primary, Auerbach, L. B., additional, Bauer, D. A., additional, Bolton, R. D., additional, Boyd, B., additional, Burman, R. L., additional, Caldwell, D. O., additional, Cohen, I., additional, Dieterle, B. D., additional, Donahue, J. B., additional, Eisner, A. M., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gray, M., additional, Gunasingha, R. M., additional, Highland, V., additional, Imlay, R., additional, Johnston, K., additional, Louis, W. C., additional, Lu, A., additional, Margulies, J., additional, McIlhany, K., additional, Metcalf, W., additional, Reeder, R. A., additional, Sandberg, V., additional, Schillaci, M., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Sullivan, M. K., additional, VanDalen, G. J., additional, Vernon, W., additional, Wang, Y-X., additional, White, D. H., additional, Whitehouse, D., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1995
Full Text
View/download PDF

31. Measurement of the reactionC12(νμ,μ−)Xnear threshold

Author

Albert, M., primary, Athanassopoulos, C., additional, Auerbach, L. B., additional, Bauer, D., additional, Bolton, R., additional, Boyd, B., additional, Burman, R. L., additional, Cohen, I., additional, Caldwell, D. O., additional, Dieterle, B. D., additional, Donahue, J. B., additional, Eisner, A. M., additional, Fazely, A., additional, Federspiel, F. J., additional, Garvey, G. T., additional, Gunasingha, R. M., additional, Highland, V., additional, Hill, J., additional, Imlay, R., additional, Johnston, K., additional, Louis, W. C., additional, Lu, A., additional, Mann, A. K., additional, Margulies, J., additional, McIlhany, K., additional, Metcalf, W., additional, Reeder, R. A., additional, Sandberg, V., additional, Schillaci, M., additional, Smith, D., additional, Stancu, I., additional, Strossman, W., additional, Sullivan, M. K., additional, VanDalen, G. J., additional, Vernon, W., additional, Wang, Y-X., additional, White, D. H., additional, Whitehouse, D., additional, Works, D., additional, Xiao, Y., additional, and Yellin, S., additional

Published
1995
Full Text
View/download PDF

33. Dilute scintillators for large-volume tracking detectors

Author

Reeder, R.A., primary, Dieterle, B.D., additional, Gregory, C., additional, Schaefer, F., additional, Schum, K., additional, Strossman, W., additional, Smith, D., additional, Christofek, L., additional, Johnston, K., additional, Louis, W.C., additional, Schillaci, M., additional, Volta, M., additional, White, D.H., additional, Whitehouse, D., additional, Albert, M., additional, Yaman, K., additional, Athanassopoulos, C., additional, Auerbach, L.B., additional, Hermida, P., additional, and Works, D., additional

Published
1993
Full Text
View/download PDF

35. Prinzmetal's angina.

Author

Athanassopoulos, C B and Maroutsos, C G

Abstract

A 23-year-old man had Prinzmetal's variant angina. After strenuous exercise and isoprenaline infusion the electrocardiogram remained normal and the patient asymptomatic. Coronary angiography gave normal results which remained normal after administration of ergometrine. An injection of methacholine induced an attack. [ABSTRACT FROM PUBLISHER]

Published
1977
Full Text
View/download PDF

38. The use of geosynthetic clay liners in heap leach pads.

Author

Athanassopoulos C. and Athanassopoulos C.

Abstract

Lining systems can consist of a geomembrane underlain by either a soil liner or a geosynthetic clay liner. When under load geomembranes are vulnerable to damage from large stones in the soil sub-grade and in the overlying drainage layer. The results of high-load static puncture tests have shown that geomembrane/geosynthetic clay liner composite liners may be subject to less puncture damage than geomembrane liners alone over compacted soil sub-grades. A comparison of expected hydraulic performance and metal recovery was performed for two proposed liner options for a hypothetical Cu heap leach project, a 1.5 mm geomembrane overlying a geosynthetic clay liner and a 1.5 mm geomembrane overlying a 0.3 m thick layer of compacted soil with a permeability of 10(-6) cm/sec. Theoretical liner leakage calculations using the semi-empirical Giroud equations showed that, for a reasonable set of assumptions, a geomembrane/geosynthetic clay liner composite liner would be expected to allow only a fraction as much leakage as a geomembrane/compacted soil composite. The improvement in pregnant leach solution capture is expected to result in a significant increase in Cu recovery., Lining systems can consist of a geomembrane underlain by either a soil liner or a geosynthetic clay liner. When under load geomembranes are vulnerable to damage from large stones in the soil sub-grade and in the overlying drainage layer. The results of high-load static puncture tests have shown that geomembrane/geosynthetic clay liner composite liners may be subject to less puncture damage than geomembrane liners alone over compacted soil sub-grades. A comparison of expected hydraulic performance and metal recovery was performed for two proposed liner options for a hypothetical Cu heap leach project, a 1.5 mm geomembrane overlying a geosynthetic clay liner and a 1.5 mm geomembrane overlying a 0.3 m thick layer of compacted soil with a permeability of 10(-6) cm/sec. Theoretical liner leakage calculations using the semi-empirical Giroud equations showed that, for a reasonable set of assumptions, a geomembrane/geosynthetic clay liner composite liner would be expected to allow only a fraction as much leakage as a geomembrane/compacted soil composite. The improvement in pregnant leach solution capture is expected to result in a significant increase in Cu recovery.

42. Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against Staphylococcus aureus .

Author

Chabán MF, I Antoniou A, Karagianni C, Toumpa D, Joray MB, Bocco JL, Sola C, M Athanassopoulos C, and Carpinella MC

Subjects
Abietanes chemistry, Abietanes pharmacology, Abietanes toxicity, Anti-Bacterial Agents chemistry, Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents toxicity, Cell Survival drug effects, Cells, Cultured, Chromosome Aberrations chemically induced, Erythrocytes drug effects, Hemolysis drug effects, Humans, Leukocytes, Mononuclear drug effects, Microbial Sensitivity Tests, Molecular Structure, Onions drug effects, Onions genetics, Structure-Activity Relationship, Abietanes chemical synthesis, Anti-Bacterial Agents chemical synthesis, Methicillin-Resistant Staphylococcus aureus drug effects
Abstract

Aim: To find alternative compounds against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA), novel derivatives from dehydroabietic acid were synthesized. Methods & results: Compound 12 was the most effective against 15 MRSA and 11 MSSA with minimum inhibitory concentration values ranging from 3.9 to 15.6 μg/ml. Although less active than 12 , compound 11 , followed by 25 and 13 , also exhibited anti-staphylococcal activity. Additional studies showed that compound 12 is devoid of toxic effect on non-target cells. A structure-activity relationship study revealed that an oxime at C-13 together with a hydroxyl at C-12 could play a key role in the activity. Conclusion: These structures, in particular compound 12 , could arise as templates for the development of agents against MRSA and MSSA.

Published
2019
Full Text
View/download PDF

43. A comprehensive evaluation of the kinetic method applied in the determination of the proton affinity of the nucleic acid molecules.

Author

Di Donna L, Napoli A, Sindona G, and Athanassopoulos C

Subjects
Energy Transfer, Kinetics, Nucleic Acids analysis, Nucleic Acids chemistry, Protons, Reproducibility of Results, Sensitivity and Specificity, Algorithms, Deoxyadenosines analysis, Deoxyadenosines chemistry, Models, Chemical, Spectrometry, Mass, Electrospray Ionization methods
Abstract

The determination of proton affinity (PA) of 2'-deoxyadenosine (dA) is used as a case study for the evaluation of possible drawbacks in the determination of the PA of the nucleic acid molecules by the kinetic method. The observed Delta PA among the different values obtain for dA by applying this procedure in its different extensions was 0.64 Kcal/mol, which is within the uncertainties of any theoretical or experimental approach. It was demonstrated that nucleosides can be generally used as reference compounds to measure the PA of an unknown nucleoside. The evaluation of Delta Delta S value for two competing reaction channels taken by proton-bound heterodimers formed by two nucleosides provides clear information on the reference base which has to be discarded from the set of reference compounds used for the estimation of an unknown PA. The PA of dA obtained with the most elaborated kinetic method (237.00 +/- 0.07 kcal/mol) is consistent with the value of 237.0 kcal/mol obtained by a simple treatment of the relative intensities of the product ions generated by two couples of the proton bound dimers formed by the nucleoside and two reference amines. The kinetic method can be, therefore, confidently used to assess the proton affinity of the multifunctional molecules such as nucleosides and nucleobases.

Published
2004
Full Text
View/download PDF

44. Nuclear magnetic resonance studies of thyrotropin-releasing hormone (TRH) and analogues incorporating D-histidine and 4-hydroxy-L-proline.

Author

Aksnes DW, Athanassopoulos C, Magafa V, Aaberg A, Francis GW, and Papaioannou D

Subjects
Amino Acid Sequence, Histidine, Hydroxyproline, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Protein Conformation, Thyrotropin-Releasing Hormone chemistry
Abstract

NMR studies have been used to examine conformational effects in thyrotropin-releasing hormone (TRH), the epimer incorporating D-His, and their analogues where trans- and cis-4-hydroxy-L-proline replace L-proline (Pro). In all six compounds the observed overall conformation of the major conformer around the Pro-His amide bond, and the observed increase of the cis/trans ratio between the conformers when L-His is replaced by D-His, can be accommodated by assuming that a ten-membered ring is formed by hydrogen bonding between the N-H of the Pro carboxamide function and the N pi-atom of the His imidazole nucleus.

Published
1996
Full Text
View/download PDF

45. Measurement of the reaction 12C( nu micro, micro-)X near threshold.

Author

Albert M, Athanassopoulos C, Auerbach LB, Bauer D, Bolton R, Boyd B, Burman RL, Cohen I I, Caldwell DO, Dieterle BD, Donahue JB, Eisner AM, Fazely A, Federspiel FJ, Garvey GT, Gunasingha RM, Highland V V, Hill J, Imlay R, Johnston K, Louis WC, Lu A, Mann AK, Margulies J, McIlhany K, Metcalf W, Reeder RA, Sandberg V V, Schillaci M, Smith D, Stancu I I, Strossman W, Sullivan MK, VanDalen GJ, Vernon W, Wang YX, White DH, Whitehouse D, Works D, Xiao Y, and Yellin S

Published
1995
Full Text
View/download PDF

46. Transient focal septal block.

Author

Athanassopoulos CB

Subjects
Aged, Angina Pectoris, Bundle-Branch Block diagnosis, Bundle-Branch Block physiopathology, Electrocardiography, Female, Humans, Myocardial Infarction physiopathology, Time Factors, Bundle of His physiopathology, Bundle-Branch Block etiology, Heart Conduction System physiopathology, Myocardial Infarction complications
Abstract

A 65-year-old woman with an acute myocardial infarction, as judged by serial enzyme changes, developed transitory Q waves in leads V2 to V4 and leads 2, 3, and aVF during an attack of pain in the chest. These Q waves were not present 12 hours later. It is suggested that these changes represent a focal block in the septal fibers of the left bundle-branch system. This defect could underlie the transient right precordial Q waves seen in myocardial infarction or ischemia, as well as the fixed Q waves of many patients without septal infarction at autopsy.

Published
1979
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results