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342 results on '"Attili, Adolfo Francesco"'

3. Impact of new DAA therapy on real clinical practice: a multicenter region-wide cohort study

Author

Lanini, Simone, Scognamiglio, Paola, Mecozzi, Alessandra, Lombardozzi, Lorella, Vullo, Vincenzo, Angelico, Mario, Gasbarrini, Antonio, Taliani, Gloria, Attili, Adolfo Francesco, Perno, Carlo Federico, De Santis, Adriano, Puro, Vincenzo, Cerqua, Fabio, D’Offizi, Gianpiero, Pellicelli, Adriano, Armignacco, Orlando, Mennini, Francesco Saverio, Siciliano, Massimo, Girardi, Enrico, Panella, Vincenzo, Ippolito, Giuseppe, and members of the Lazio Region HCV treatment group

Published
2018
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9. Recipient perioperative cholesterolaemia and graft cholesterol metabolism gene expression predict liver transplant outcome

Author

Ginanni Corradini, Stefano, Siciliano, Maria, Parlati, Lucia, Molinaro, Antonio, Cantafora, Alfredo, Poli, Edoardo, Mennini, Gianluca, Melandro, Fabio, Vestri, Anna Rita, Merli, Manuela, Bianco, Paolo, Corsi, Alessandro, Toniutto, Pierluigi, Bitetto, Davide, Falleti, Edmondo, Attili, Adolfo Francesco, Berloco, Pasquale, and Rossi, Massimo

Published
2014
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13. Dissolution of Gallbladder Stones with Methyl tert-Butyl Ether and Stone Recurrence (A European Survey)

Author

Hellstern, Alfred, Leuschner, Ulrich, Benjaminov, Ala, Ackermann, Hanns, Heine, Thomas, Festi, Davide, Orsini, Monica, Roda, Enrico, Northfield, Tim C., Jazrawi, Riadh, Kurtz, Winfried, Schmeck-Lindenau, Hans Joachim, Stumpf, Jochen, Eidsvoll, Britt E., Aadland, Erling, Lux, Gerd, Boehnke, Eckhart, Wurbs, Ditmar, Delhaye, Myriam, Cremer, Michel, Sinn, Ingolf, Horing, Erich, Gaisberg, Ulrich V., Neubrand, Michael, Sauerbruch, Tilmann, Salamon, Vladimir, Swobodnik, Werner, Sanden, Hasko V., Schmitt, Wolfgang, Kaser, Thomas, Schomerus, Hans, Wechsler, Johannes Georg, Janowitz, Paul, Lohmann, Jorn, Porst, Heiner, Attili, Adolfo Francesco, Bartels, Eberhard, Wolf, Wolfgang Arnold, Strohm, Dieter, and Paul, Fred

Published
1998
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18. Preharvest donor hyperoxia predicts good early graft function and longer graft survival after liver transplantation

Author

Corradini, Stefano Ginanni, Elisei, Walter, De Marco, Rosanna, Siciliano, Maria, Iappelli, Massimo, Pugliese, Francesco, Ruberto, Franco, Nudo, Francesco, Pretagostini, Renzo, Bussotti, Alessandro, Mennini, Gianluca, Eramo, Annarita, Liguori, Francesca, Merli, Manuela, Attili, Adolfo Francesco, Muda, Andrea Onetti, Natalizi, Stefania, Berloco, Pasquale, and Rossi, Massimo

Published
2005
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29. Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes

Author

Alvaro, Domenico, Alpini, G., Onori, Paolo, Franchitto, Antonio, Glaser, S., Lesage, G., Alessandro, Gigliozzi, Vetuschi, A., Morini, S., Attili, Adolfo Francesco, Antonella, Vetuschi, Shannon, Glaser, Gene Le Sage, Gianfranco, Alpini, and Gaudio, Eugenio

Subjects
medicine.medical_specialty, Ovariectomy, Cholangiocyte proliferation, Estrogen receptor, Apoptosis, Biology, digestive system, Cholangiocyte, Cholestasis, Internal medicine, medicine, Animals, Estrogen Receptor beta, Rats, Wistar, Ligation, Estrogen receptor beta, estrogen-receptor, cells, regeneration, apoptosis, primary biliary-cirrhosis, breast-cancer, liver, pure antiestrogen, duct-ligated rats, growth, TUNEL assay, Estradiol, Hepatology, Ovary, Estrogen Receptor alpha, Gastroenterology, Organ Size, medicine.disease, Immunohistochemistry, digestive system diseases, Rats, Endocrinology, Liver, Receptors, Estrogen, Ovariectomized rat, Female, Bile Ducts, Estrogen receptor alpha, Cell Division, hormones, hormone substitutes, and hormone antagonists
Abstract

We evaluated the effects of ovariectomy (OVX) and estrogen replacement treatment on cholangiocyte proliferation induced by bile duct ligation (BDL).BDL (2 weeks) was performed in ovariectomized rats and the proliferative and apoptotic activity compared with normal, with BDL control rats, and with BDL +/- OVX rats treated with 17-beta estradiol.OVX induced a significant (P0.01) reduction of bile duct mass in BDL rats. The reduction of bile duct mass induced by OVX was associated with a decreased expression of estrogen receptor (ER)-alpha (2.5-fold) and, mainly, ER-beta (35-fold). Proliferating cellular nuclear antigen (PCNA) expression in cholangiocytes was impaired by OVX, indicating depression of proliferation, whereas terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) and Fas positivity were markedly enhanced, indicating activation of Fas-mediated apoptosis. Administration of 17-beta estradiol during BDL in OVX rats induced a normalization of bile duct mass, ER expression, cholangiocyte proliferation, and apoptosis (Fas and TUNEL) in comparison with untreated BDL rats.Our findings support the role of endogenous estrogens in sustaining the enhanced proliferative and secretory activities of cholangiocytes in cholestasis. On the basis of these data, the hypothesis of an estrogenic functional deficiency in chronic cholestatic liver diseases should merit careful attention.

Published
2002
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30. Diet and gallstones in italy: The cross-sectional MICOL results

Author

Attili, Adolfo Francesco, Emanuele, Scafato, Roberto, Marchioli, Rosa Maria Marfisi, Davide, Festi, Micol Group, T. H. E., GINANNI CORRADINI, Stefano, and DE SANTIS, Adriano

Subjects
Male, medicine.medical_specialty, Cross-sectional study, food frequency questionnaire, Population, biliary lipids, Negative association, middle-aged women, Cohort Studies, bile cholesterol saturation, Animal science, Cholelithiasis, Internal medicine, Epidemiology, medicine, Humans, risk-factors, education, Meal, education.field_of_study, fed prairie dog, pigment gallstones, Hepatology, business.industry, symptomatic gallstones, Gallstones, medicine.disease, clinical gallbladder-disease, Diet, gall stone disease, Endocrinology, Italy, Relative risk, Female, business, Cohort study
Abstract

Fifteen thousand nine hundred ten men and 13,674 women (age, 30-69 years) were enrolled in an epidemiological survey of the general population, between December 1984 and April 1987. Each participant was submitted to ultrasonography (US) of the gallbladder and completed a food-frequency questionnaire, covering 38 food items. A common portion size was identified and subjects were asked how often each item was consumed. Nutrient intake was computed by multiplying the intake frequency and nutrient content per portion for each item, and then by summing the product over all foods. Each nutrient intake was adjusted for energy intake. Alcohol intake was calculated by summing the consumption of wine, beer, and liquor. Having excluded subjects aware of having gallstones (GS) or previously submitted to cholecystectomy (to avoid prothopatic bias), 787 males and 1,014 females with GS and 14,272 males and 10,836 females without GS were available for analysis. Relative risks (RR) of GS were computed by quintiles of nutrient intake. The overnight fasting period was calculated as the difference between the specified time of dinner and the time of the next meal (breakfast or lunch). A significant negative association was found between RR of GS and total energy intake for males (chi2 for trend = 8.37; P = .004), fiber intake for females (chi2 = 5.45; P = .02), and daily alcohol consumption for males (chi2 = 10.86; P = .001). A positive association was observed between RR of GS and carbohydrate (chi2 = 5.95; P = .01 for males; chi2 = 9.39; P = .002 for females) and protein intake only for males (chi2 = 10.92; P = .01). Prevalence of GS was higher among subjects who had an overnight fasting period of over 12 hours than subjects with that of less than 12 hours. (RR: 1.35; 95% CI: 1.01-1.80 for males; RR: 1.28; 95% CI: 1.03-1.60 for females). These data do not confirm that high energy intake is associated with an increased risk of GS. Factors protecting against GS comprise: low carbohydrate (males and females) and protein (males) intakes, high fiber (females) and moderate alcohol intake (males) consumption, and a shorter overnight fasting period for both sexes.

Published
1998
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43. Patterns of treatment and costs of intermediate and advanced hepatocellular carcinoma management in four Italian centers

Author

Colombo,Giorgio Lorenzo, Cammà ,Calogero, Attili,Adolfo Francesco, Ganga,Roberto, Gaeta,Giovanni Battista, Brancaccio,Giuseppina, Franzini,Jean Marie, Volpe,Marco, Turchetti,Giuseppe, Colombo,Giorgio Lorenzo, Cammà ,Calogero, Attili,Adolfo Francesco, Ganga,Roberto, Gaeta,Giovanni Battista, Brancaccio,Giuseppina, Franzini,Jean Marie, Volpe,Marco, and Turchetti,Giuseppe

Abstract

Giorgio Lorenzo Colombo,1 Calogero Cammà,2 Adolfo Francesco Attili,3 Roberto Ganga,4 Giovanni Battista Gaeta,5 Giuseppina Brancaccio,5 Jean Marie Franzini,6 Marco Volpe,6 Giuseppe Turchetti7 1Department of Drug Sciences, University of Pavia, Pavia, Italy; 2Section of Gastroenterology, Di.Bi.M.I.S., University of Palermo, Palermo, Italy; 3Department of Clinical Medicine, University of Rome (La Sapienza) Rome, Italy; 4Clinical Medicine Division, Ospedale Brotzu, Cagliari, Italy; 5Viral Hepatitis Unit, Second University, Naples, Italy; 6Business Integration Partners S.p.A., Milan, Italy; 7Scuola Superiore Sant’Anna, Pisa, Italy Background: Hepatocellular carcinoma (HCC) is a severe health condition associated with high hospitalizations and mortality rates, which also imposes a relevant economic burden.Purpose: The aim of the present survey is to investigate treatment strategies and related costs for HCC in the intermediate and advanced stages of the disease. Patients and methods: The survey was conducted in four Italian centers through structured interviews with physicians. Information regarding the stage of disease, treatments performed, and related health care resource consumption was included in the questionnaire. Direct health care cost per patient associated with the most relevant treatments such as sorafenib, transarterial chemoembolization (TACE), and transarterial radioembolization (TARE) was evaluated.Results: Between 2013 and 2014, 285 patients with HCC were treated in the four participating centers; of these, 80 were in intermediate stage HCC (Barcelona Clinic Liver Cancer Classification [BCLC] B), and 57 were in the advanced stage of the disease (BCLC C). In intermediate stage HCC, the most frequent first-line treatment was TACE (63%) followed by sorafenib (15%), radiofrequency ablation (14%), and TARE (1.3%). In the advanced stage of HCC, the most frequently used first-line therapy was sorafenib (56%), followed by best supportive care

Published
2015

45. La cirrosi epatica

Author

Attili, Adolfo Francesco and Merli, Manuela

Published
2010

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