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8 results on '"Aw, Pauline Poh Kim"'

1. Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity

Author

Narmada, Balakrishnan Chakrapani, Khakpoor, Atefeh, Shirgaonkar, Niranjan, Narayanan, Sriram, Aw, Pauline Poh Kim, Singh, Malay, Ong, Kok Haur, Owino, Collins Oduor, Ng, Jane Wei Ting, Yew, Hui Chuing, Binte Mohamed Nasir, Nu Soibah, Au, Veonice Bijin, Sng, Reina, Kaliaperumal, Nivashini, Khine, Htet Htet Toe Wai, di Tocco, Francesca Casuscelli, Masayuki, Otsuka, Naikar, Shamita, Ng, Hui Xin, Chia, Su Li, Seah, Cindy Xin Yi, Alnawaz, Myra HJ., Wai, Chris Lee Yoon, Tay, Amy Yuh Ling, Mangat, Kamarjit Singh, Chew, Valerie, Yu, Weimiao, Connolly, John Edward, Periyasamy, Giridharan, Plissonnier, Marie-Laure, Levrero, Massimo, Lim, Seng Gee, and DasGupta, Ramanuj

Published
2024
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2. Single cell profiling of functionally cured Chronic Hepatitis B patients reveals the emergence of activated innate and an altered adaptive immune response in the intra-hepatic envrionment

Author

Narmada, Balakrishnan Chakrapani, primary, Khakpoor, Atefeh, additional, Shirgaonkar, Niranjan, additional, Narayanan, Sriram, additional, Aw, Pauline Poh Kim, additional, Singh, Malay, additional, Ong, Kok Haur, additional, Owino, Collins Oduor, additional, Ng, Jane Wei Ting, additional, Yew, Hui Chuing, additional, Binte Mohamed Nasir, Nu Soibah, additional, AU, Veonice Bijin, additional, Sng, Reina, additional, Kaliaperumal, Nivashini, additional, Khine, Htet Htet Toe Wai, additional, Ng, Hui Xin, additional, Chia, Su Li, additional, Seah, Cindy Xin Yi, additional, HJ Alnawaz, Myra, additional, Wai, Chris Lee Yoon, additional, Tay, Amy Yuh Ling, additional, Yu, Weimiao, additional, Connolly, John Edward, additional, Periyasamy, Giridharan, additional, Lim, Seng Gee, additional, and DasGupta, Ramanuj, additional

Published
2022
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5. Dengue virus not detected in human semen

Author

Molton, James S, primary, Low, Isaac, additional, Choy, Milly Ming Ju, additional, Aw, Pauline Poh Kim, additional, Hibberd, Martin L, additional, Tambyah, Paul A, additional, and Wilder-Smith, Annelies, additional

Published
2018
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8. Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk.

Author

Lee GH, Tan BH, Teo EC, Lim SG, Dan YY, Wee A, Aw PP, Zhu Y, Hibberd ML, Tan CK, Purdy MA, and Teo CG

Subjects
Animals, Antiviral Agents therapeutic use, Genotype, Hepatitis E diagnosis, Hepatitis E drug therapy, Hepatitis E transmission, Hepatitis E virus genetics, Hepatitis, Chronic diagnosis, Hepatitis, Chronic drug therapy, Humans, Immunocompromised Host, Immunosuppressive Agents adverse effects, Male, Middle Aged, Phylogeny, Time Factors, Treatment Outcome, Camelus virology, Food Contamination, Hepatitis E virology, Hepatitis E virus pathogenicity, Hepatitis, Chronic virology, Liver Transplantation adverse effects, Meat virology, Milk virology, Zoonoses
Abstract

There have been increasing reports of food-borne zoonotic transmission of hepatitis E virus (HEV) genotype 3, which causes chronic infections in immunosuppressed patients. We performed phylogenetic analyses of the HEV sequence (partial and full-length) from 1 patient from the Middle East who underwent liver transplantation, and compared it with other orthohepevirus A sequences. We found the patient to be infected by camelid HEV. This patient regularly consumed camel meat and milk, therefore camelid HEV, which is genotype 7, might infect human beings. Our finding links consumption of camel-derived food products to post-transplantation hepatitis E, which, if detected at early stages, can be cured with antiviral therapy and reduced administration of immunosuppressive agents., (Copyright © 2016 AGA Institute. Published by Elsevier Inc. All rights reserved.)

Published
2016
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