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322 results on '"Aziz-Sultan, Mohammad A."'

1. Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study

Author

El Naamani, Kareem, Mastorakos, Panagiotis, Adeeb, Nimer, Lan, Mathews, Castiglione, James, Khanna, Omaditya, Diestro, Jose Danilo Bengzon, McLellan, Rachel M., Dibas, Mahmoud, Vranic, Justin E., Aslan, Assala, Cuellar-Saenz, Hugo H., Guenego, Adrien, Carnevale, Joseph, Saliou, Guillaume, Ulfert, Christian, Möhlenbruch, Markus, Foreman, Paul M., Vachhani, Jay A., Hafeez, Muhammad U., Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Michelozzi, Caterina, Spears, Julian, Panni, Pietro, Griessenauer, Christoph J., Asadi, Hamed, Regenhardt, Robert W., Stapleton, Christopher J., Ghozy, Sherief, Siddiqui, Adnan, Patel, Nirav J., Kan, Peter, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Zanaty, Mario, Ghosh, Ritam, Abbas, Rawad, Amllay, Abdelaziz, Tjoumakaris, Stavropoula I., Gooch, Michael R., Cancelliere, Nicole M., Herial, Nabeel A., Rosenwasser, Robert H., Zarzour, Hekmat, Schmidt, Richard F., Pereira, Vitor Mendes, Patel, Aman B., Jabbour, Pascal, and Dmytriw, Adam A.

Published
2024
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2. Somatic Variants in SVIL in Cerebral Aneurysms

Author

Lai, Pui Man Rosalind, Ryu, Jee-Yeon, Park, Sang-Cheol, Gross, Bradley A, Dickinson, Lawrence D, Dagen, Sarajune, Aziz-Sultan, Mohammad Ali, Boulos, Alan S, Barrow, Daniel L, Batjer, H Hunt, Blackburn, Spiros, Chang, Edward F, Chen, P Roc, Colby, Geoffrey P, Cosgrove, Garth Rees, David, Carlos A, Day, Arthur L, Frerichs, Kai U, Niemela, Mika, Ojemann, Steven G, Patel, Nirav J, Shi, Xiangen, Valle-Giler, Edison P, Wang, Anthony C, Welch, Babu G, Zusman, Edie E, Weiss, Scott T, and Du, Rose

Subjects
Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Brain Disorders, Biotechnology, Cardiovascular, Stroke, Neurosciences, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Clinical sciences
Abstract

Background and objectivesWhile somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.MethodsWe performed whole-exome sequencing on aneurysm tissues and paired peripheral blood. RNA sequencing and the CRISPR/Cas9 system were then used to perform functional validation of our results.ResultsSomatic variants involved in supervillin (SVIL) or its regulation were found in 17% of aneurysm tissues. In the presence of a mutation in the SVIL gene, the expression level of SVIL was downregulated in the aneurysm tissue compared with normal control vessels. Downstream signaling pathways that were induced by knockdown of SVIL via the CRISPR/Cas9 system in vascular smooth muscle cells (vSMCs) were determined by evaluating changes in gene expression and protein kinase phosphorylation. We found that SVIL regulated the phenotypic modulation of vSMCs to the synthetic phenotype via Krüppel-like factor 4 and platelet-derived growth factor and affected cell migration of vSMCs via the RhoA/ROCK pathway.DiscussionWe propose that somatic variants form a novel mechanism for the development of cerebral aneurysms. Specifically, somatic variants in SVIL result in the phenotypic modulation of vSMCs, which increases the susceptibility to aneurysm formation. This finding suggests a new avenue for the therapeutic intervention and prevention of cerebral aneurysms.

Published
2022

3. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Knopman, Jared, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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4. Acute ischaemic stroke associated with SARS-CoV-2 infection in North America

Author

Dmytriw, Adam A, Dibas, Mahmoud, Phan, Kevin, Efendizade, Aslan, Johanna, Ospel, Schirmer, Clemens, Settecase, Fabio, Heran, Manraj KS, Kühn, Anna Luisa, Puri, Ajit S, Menon, Bijoy K, Sivakumar, Sanjeev, Mowla, Askan, Vela-Duarte, Daniel, Linfante, Italo, Dabus, Guilherme C, Regenhardt, Robert W, D'Amato, Salvatore, Rosenthal, Joseph A, Zha, Alicia, Talukder, Nafee, Sheth, Sunil A, Hassan, Ameer E, Cooke, Daniel L, Leung, Lester Y, Malek, Adel M, Voetsch, Barbara, Sehgal, Siddharth, Wakhloo, Ajay K, Goyal, Mayank, Wu, Hannah, Cohen, Jake, Ghozy, Sherief, Turkel-Parella, David, Farooq, Zerwa, Vranic, Justin, Rabinov, James D, Stapleton, Christopher J, Minhas, Ramandeep, Velayudhan, Vinodkumar, Chaudhry, Zeshan Ahmed, Xavier, Andrew, Bullrich, Maria Bres, Pandey, Sachin, Sposato, Luciano A, Johnson, Stephen A, Gupta, Gaurav, Khandelwal, Priyank, Ali, Latisha, Liebeskind, David S, Farooqui, Mudassir, Ortega-Gutierrez, Santiago, Nahab, Fadi, Jillella, Dinesh V, Chen, Karen, Aziz-Sultan, Mohammad Ali, Abdalkader, Mohamad, Kaliaev, Artem, Nguyen, Thanh N, Haussen, Diogo C, Nogueira, Raul G, Haq, Israr Ul, Zaidat, Osama O, Sanborn, Emma, Leslie-Mazwi, Thabele M, Patel, Aman B, Siegler, James E, and Tiwari, Ambooj

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Stroke, Clinical Research, Neurosciences, Good Health and Well Being, Brain Ischemia, COVID-19, Humans, Ischemic Stroke, Middle Aged, Retrospective Studies, SARS-CoV-2, Thrombectomy, Treatment Outcome, stroke, interventional, North American Neurovascular COVID-19 (NAN-C) Consortium & Society of Vascular and Interventional Neurology (SVIN) Investigators, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, Clinical sciences
Abstract

BackgroundTo analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome.MethodsMulticentre retrospective cohort study of COVID-19 patients with AIS who presented to 30 stroke centres in the USA and Canada between 14 March and 30 August 2020. The primary endpoint was poor functional outcome, defined as a modified Rankin Scale (mRS) of 5 or 6 at discharge. Secondary endpoints include favourable outcome (mRS ≤2) and mortality at discharge, ordinal mRS (shift analysis), symptomatic intracranial haemorrhage (sICH) and occurrence of in-hospital complications.ResultsA total of 216 COVID-19 patients with AIS were included. 68.1% (147/216) were older than 60 years, while 31.9% (69/216) were younger. Median [IQR] National Institutes of Health Stroke Scale (NIHSS) at presentation was 12.5 (15.8), and 44.2% (87/197) presented with large vessel occlusion (LVO). Approximately 51.3% (98/191) of the patients had poor outcomes with an observed mortality rate of 39.1% (81/207). Age >60 years (aOR: 5.11, 95% CI 2.08 to 12.56, p

Published
2022

5. Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Jared Knopman, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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6. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
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8. Outcomes of mechanical thrombectomy in anticoagulated patients with acute distal and medium vessel stroke

Author

Salim, Hamza, primary, Musmar, Basel, additional, Adeeb, Nimer, additional, Yedavalli, Vivek, additional, Lakhani, Dhairya, additional, Grewal, Sahibjot Singh, additional, El Naamani, Kareem, additional, Henninger, Nils, additional, Sundararajan, Sri Hari, additional, Kühn, Anna Luisa, additional, Khalife, Jane, additional, Ghozy, Sherief, additional, Scarcia, Luca, additional, Tan, Benjamin YQ, additional, Regenhardt, Robert W, additional, Heit, Jeremy J, additional, Cancelliere, Nicole M, additional, Bernstock, Joshua D, additional, Rouchaud, Aymeric, additional, Fiehler, Jens, additional, Sheth, Sunil, additional, Puri, Ajit S, additional, Dyzmann, Christian, additional, Colasurdo, Marco, additional, Barreau, Xavier, additional, Renieri, Leonardo, additional, Filipe, João Pedro, additional, Harker, Pablo, additional, Radu, Răzvan Alexandru, additional, Abdalkader, Mohamad, additional, Klein, Piers, additional, Marotta, Thomas R, additional, Spears, Julian, additional, Ota, Takahiro, additional, Mowla, Ashkan, additional, Jabbour, Pascal, additional, Biswas, Arundhati, additional, Clarençon, Frédéric, additional, Siegler, James E, additional, Nguyen, Thanh N, additional, Varela, Ricardo, additional, Baker, Amanda, additional, Essibayi, Muhammed Amir, additional, Altschul, David, additional, Gonzalez, Nestor R, additional, Möhlenbruch, Markus A, additional, Costalat, Vincent, additional, Gory, Benjamin, additional, Stracke, Christian Paul, additional, Aziz-Sultan, Mohammad Ali, additional, Hecker, Constantin, additional, Shaikh, Hamza, additional, Liebeskind, David S, additional, Pedicelli, Alessandro, additional, Alexandre, Andrea M, additional, Tancredi, Illario, additional, Faizy, Tobias D, additional, Kalsoum, Erwah, additional, Lubicz, Boris, additional, Patel, Aman B, additional, Pereira, Vitor Mendes, additional, Guenego, Adrien, additional, Dmytriw, Adam A, additional, Amllay, Abdelaziz, additional, Vagal, Achala, additional, ter Schiphorst, Adrien, additional, Thomas, Ajith J., additional, Gopinathan, Anil, additional, Dusart, Anne, additional, Capirossi, Carolina, additional, Mounayer, Charbel, additional, Weyland, Charlotte, additional, Hsieh, Cheng-Yang, additional, Griessenauer, Christoph J., additional, Stapleton, Christopher J., additional, Bellante, Flavio, additional, Marnat, Gaultier, additional, Forestier, Géraud, additional, Cuellar-Saenz, Hugo H., additional, Valente, Iacopo, additional, Sibon, Igor, additional, Rabinov, James D., additional, Berge, Jérôme, additional, Jesser, Jessica, additional, Carlos Martinez-Gutierrez, Juan, additional, Premat, Kevin, additional, Yeo, Leonard LL., additional, Chervak, Lina, additional, Meyer, Lukas, additional, Elhorany, Mahmoud, additional, and Quintero-Consuegra, Miguel, additional

Published
2024
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10. Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke)

Author

Froehler, Michael T, Saver, Jeffrey L, Zaidat, Osama O, Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P, Haussen, Diogo C, Hellinger, Frank R, Yavagal, Dileep R, Yao, Tom L, Liebeskind, David S, Jadhav, Ashutosh P, Gupta, Rishi, Hassan, Ameer E, Martin, Coleman O, Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G, Gandhi, Ravi H, Peterson, Eric C, Dashti, Shervin R, Given, Curtis A, Mehta, Brijesh P, Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H, Kvamme, Peter, Grobelny, Thomas J, Hussain, Muhammad S, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J, Ecker, Robert D, Schirmer, Clemens M, Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P, Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H, Dumont, Travis M, Alhajeri, Abdulnasser, Taqi, M Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S, Chitale, Rohan, Deshaies, Eric M, Robinson, David H, Kallmes, David F, Baxter, Blaise W, Jumaa, Mouhammad A, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D, Suzuki, Shuichi, Fessler, Richard D, Almandoz, Josser E Delgado, Martin, Jerry C, and Mueller-Kronast, Nils H

Subjects
Stroke, Clinical Research, Brain Disorders, Endovascular Procedures, Hospitals, Humans, Ischemia, Patient Transfer, Prospective Studies, Registries, Survival Analysis, Thrombectomy, Time Factors, Treatment Outcome, emergency medical services, endovascular treatment, ischemic stroke, stent retriever, systems of care, STRATIS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Abstract

BackgroundEndovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.MethodsSTRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or without intravenous tissue plasminogen activator and were admitted to endovascular-capable centers via either interhospital transfer or direct presentation. The primary clinical outcome was functional independence (modified Rankin Score 0-2) at 90 days. We assessed (1) real-world time metrics of stroke care delivery, (2) outcome differences between direct and transfer patients undergoing MT, and (3) the potential impact of local hospital bypass.ResultsA total of 984 patients were analyzed. Median onset-to-revascularization time was 202.0 minutes for direct versus 311.5 minutes for transfer patients (P

Published
2017

11. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, primary, Musmar, Basel, additional, Salim, Hamza, additional, Aslan, Assala, additional, Cancelliere, Nicole M, additional, McLellan, Rachel M, additional, Algin, Oktay, additional, Ghozy, Sherief, additional, Dibas, Mahmoud, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Carnevale, Joseph Anthony, additional, Saliou, Guillaume, additional, Mastorakos, Panagiotis, additional, El Naamani, Kareem, additional, Shotar, Eimad, additional, Premat, Kevin, additional, Möhlenbruch, Markus A, additional, Kral, Michael, additional, Doron, Omer, additional, Chung, Charlotte, additional, Salem, Mohamed M, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Shaikh, Hamza, additional, Župančić, Vedran, additional, Hafeez, Muhammad Ubaid, additional, Catapano, Joshua S, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Ibrahim, Mohamed K, additional, Mohammed, Marwa A, additional, Imamoglu, Cetin, additional, Bayrak, Ahmet, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Hasan, Zuha, additional, Starke, Robert M, additional, Hassan, Ameer E, additional, Ogilvie, Mark, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Brinjikji, Waleed, additional, Nawka, Marie Teresa, additional, Psychogios, Marios-Nikos, additional, Ulfert, Christian, additional, Diestro, Jose Danilo Bengzon, additional, Pukenas, Bryan, additional, Burkhardt, Jan Karl, additional, Huynh, Thien J, additional, Martinez-Gutierrez, Juan Carlos, additional, Essibayi, Muhammed Amir, additional, Sheth, Sunil A, additional, Spiegel, Gary, additional, Tawk, Rabih, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Nossek, Erez, additional, Raz, Eytan, additional, Killer-Oberpfalzer, Monika, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan H, additional, Brook, Allan L, additional, Altschul, David, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Regenhardt, Robert W, additional, Stapleton, Christopher J, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Tjoumakaris, Stavropoula I, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Cuellar, Hugo H, additional, Jabbour, Pascal M, additional, Pereira, Vitor M, additional, Patel, Aman B, additional, and Adeeb, Nimer, additional

Published
2024
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13. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Diestro, Jose Danilo Bengzon, Dibas, Mahmoud, Phan, Kevin, Sweid, Ahmad, Cuellar-Saenz, Hugo H., Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Sundararajan, Sri Hari, Carnevale, Joseph, Saliou, Guillaume, Möhlenbruch, Markus, Vranic, Justin E., Rabinov, James D., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Abbas, Rawad, Inoue, Yasuaki, Capirossi, Carolina, Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna Luisa, Michelozzi, Caterina, Elens, Stéphanie, Regenhardt, Robert W., Ghozy, Sherief, Alotaibi, Naif M., Tjoumakaris, Stavropoula, Starke, Robert M., Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Brooks, Mark, Maingard, Julian, Jhamb, Ashu, Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Savardekar, Amey, Boddu, Srikanth, Knopman, Jared, Limbucci, Nicola, Chen, Karen S., Aziz-Sultan, Mohammad A., Stapleton, Christopher J., Jabbour, Pascal, Cognard, Christophe, Patel, Aman B., and Adeeb, Nimer

Published
2021
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15. Endovascular Applications for the Management of High-Grade Gliomas in the Modern Era.

Author

Kappel, Ari D., Jha, Rohan, Guggilapu, Saibaba, Smith, William J., Feroze, Abdullah H., Dmytriw, Adam A., Vicenty-Padilla, Juan, Alcedo Guardia, Rodolfo E., Gessler, Florian A., Patel, Nirav J., Du, Rose, See, Alfred P., Peruzzi, Pier Paolo, Aziz-Sultan, Mohammad A., and Bernstock, Joshua D.

Subjects
GLIOMA treatment, PATIENT safety, BLOOD-brain barrier, ENDOVASCULAR surgery, TUMOR grading, MINIMALLY invasive procedures, DRUG delivery systems, ULTRASONIC imaging, CANCER chemotherapy
Abstract

Simple Summary: This review discusses new treatments for high-grade gliomas (HGGs), aggressive brain tumors that are difficult to treat. It focuses on emerging endovascular therapies and future directions. Endovascular methods use catheters in a minimally invasive manner to deliver drugs to the tumor through blood vessels in the brain while limiting harm to the rest of the body. Super-selective intra-arterial cerebral infusion (SSIACI) is an endovascular technique that aims to deliver treatments directly to the tumor by reaching the closest blood vessels supplying the tumor. Many challenges remain to fully adopting these techniques in clinical practice, including the ability of drugs to cross the blood–brain barrier, and getting the drugs to stay in the tumor for long enough before they are washed out by normal blood in the brain. Focused ultrasound and hyperosmotic disruption are techniques which might help with these challenges. Researchers are investigating new drugs beyond traditional chemotherapies, such as radiation embedded molecules and immune-based therapies. Future directions include monitoring tumors with endovascular sampling; changing drug formulations to stay in the tumor longer; and investigating other treatments, like radioembolization. These endovascular strategies have the potential to improve how HGGs are treated, but more research is needed to ensure they work well and are safe for patients. High-grade gliomas (HGGs) have a poor prognosis and are difficult to treat. This review examines the evolving landscape of endovascular therapies for HGGs. Recent advances in endovascular catheter technology and delivery methods allow for super-selective intra-arterial cerebral infusion (SSIACI) with increasing precision. This treatment modality may offer the ability to deliver anti-tumoral therapies directly to tumor regions while minimizing systemic toxicity. However, challenges persist, including blood–brain barrier (BBB) penetration, hemodynamic complexities, and drug–tumor residence time. Innovative adjunct techniques, such as focused ultrasound (FUS) and hyperosmotic disruption, may facilitate BBB disruption and enhance drug penetration. However, hemodynamic factors that limit drug residence time remain a limitation. Expanding therapeutic options beyond chemotherapy, including radiotherapy and immunobiologics, may motivate future investigations. While preclinical and clinical studies demonstrate moderate efficacy, larger randomized trials are needed to validate the clinical benefits. Additionally, future directions may involve endovascular sampling for peri-tumoral surveillance; changes in drug formulations to prolong residence time; and the exploration of non-pharmaceutical therapies, like radioembolization and photodynamic therapy. Endovascular strategies hold immense potential in reshaping HGG treatment paradigms, offering targeted and minimally invasive approaches. However, overcoming technical challenges and validating clinical efficacy remain paramount for translating these advancements into clinical care. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT).

Author

Fiorella, David, Molyneux, Andy, Coon, Alex, Szikora, Istvan, Saatci, Isil, Baltacioglu, Feyyaz, Aziz-Sultan, Mohammad A., Hoit, Daniel, Delgado Almandoz, Josser E., Elijovich, Lucas, Cekirge, H. Saruhan, Byrne, James, Klisch, Joachim, and Arthur, Adam S.

Subjects
PATIENT aftercare, CLINICAL trials, THERAPEUTIC embolization, TREATMENT effectiveness, DIAGNOSTIC imaging, REOPERATION, DESCRIPTIVE statistics, RESEARCH funding, ADVERSE health care events, PATIENT safety, INTRACRANIAL aneurysms, LONGITUDINAL method, EVALUATION
Abstract

Introduction The US Woven EndoBridge Intra-saccular Therapy (WEB-IT) study is a pivotal, prospective, single arm, investigational device exemption study to evaluate the safety and effectiveness of the WEB device for the treatment of wide neck bifurcation aneurysms (WNBAs). We present complete 5 year data for the cohort of 150 patients. Methods 150 patients with WNBAs were enrolled at 21 US and six international centers. Imaging from the index procedure, 6 month, 1 year, 3 year, and 5 year follow-up were reviewed by a core laboratory. Adverse events were reviewed and adjudicated by a clinical events adjudicator. Results 83 patients had 5 year follow-up imaging and 123 had clinical follow-up. No ruptured (0/9) or unruptured aneurysm (0/141) rebled or bled during follow-up. No new device or procedure related adverse events or serious adverse events were reported after 1 year. At 5 years, using the LOCF method, complete occlusion was observed in 58.1% and adequate occlusion in 87.2% of patients. For patients with both 1 year and 5 year occlusion statuses available, 76.8% (63/82) of aneurysms remained stable or improved with no retreatment. After 1 year, 18 aneurysms were retreated, 11 of which were adequately occluded at 1 year, and 15 of which were retreated in the absence of any deterioration in occlusion grade. Conclusions Five year follow-up data from the WEB-IT study demonstrated that the WEB device was safe and effective when used in the treatment of WNBAs. Aneurysm occlusion rates achieved at 1 year follow-up were durable, with rates of progressive thrombosis far exceeding rates of recurrence over time. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry

Author

Zaidat, Osama O., Mueller-Kronast, Nils H., Hassan, Ameer E., Haussen, Diogo C., Jadhav, Ashutosh P., Froehler, Michael T., Jahan, Reza, Ali Aziz-Sultan, Mohammad, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Gupta, Rishi, Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin, Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad Shazam, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Chebl, Alex Bou, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, Muhammad A., Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David, Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammed, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado-Almandoz, Josser, Martin, Jerry C., and Liebeskind, David S.

Published
2019
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25. Transradial versus transfemoral access for embolization of intracranial aneurysms with the Woven EndoBridge device: a propensity score–matched study

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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26. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Dibas, Mahmoud, additional, Ghozy, Sherief, additional, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Tjoumakaris, Stavropoula, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, and Patel, Aman B., additional

Published
2022
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29. Multicenter Study for the Treatment of Sidewall versus Bifurcation Intracranial Aneurysms with Use of Woven EndoBridge (WEB)

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Kandregula, Sandeep, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Aslan, Assala, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Regenhardt, Robert W., additional, Savardekar, Amey, additional, Mamilly, Ahmed, additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Parra Farinas, Carmen, additional, Tutino, Vincent M., additional, Inoue, Yasuaki, additional, Mirshahi, Shervin, additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Brehm, Alex, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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30. Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Author

Diestro, Jose Danilo Bengzon, primary, Dibas, Mahmoud, additional, Adeeb, Nimer, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Guenego, Adrien, additional, Lay, Sovann V, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Shotar, Eimad, additional, Premat, Kevin, additional, El Naamani, Kareem, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus A., additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Rai, Hamid, additional, Tutino, Vincent M, additional, Mirshani, Shervin, additional, Ghozy, Sherief, additional, Harker, Pablo, additional, Alotaibi, Naif M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Goren, Oded, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Parra-Fariñas, Carmen, additional, Bres Bullrich, Maria, additional, Mayich, Michael, additional, Salem, Mohamed M, additional, Burkhardt, Jan-Karl, additional, Jankowitz, Brian T, additional, Domingo, Ricardo A, additional, Huynh, Thien, additional, Tawk, Rabih, additional, Ulfert, Christian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Stapleton, Christopher J, additional, Knopman, Jared, additional, Jabbour, Pascal, additional, Tjoumakaris, Stavropoula, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Aziz-Sultan, Mohammad A, additional, Cuellar-Saenz, Hugo H, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
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33. Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry

Author

Mueller-Kronast, Nils H., Zaidat, Osama O., Froehler, Michael T., Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Liebeskind, David S., Jadhav, Ashutosh P., Gupta, Rishi, Hassan, Ameer E., Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin R., Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad S., Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, M. Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David H., Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammad A., Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado Almandoz, Josser E., Martin, Jerry C., and Haussen, Diogo C.

Published
2017
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34. Transradial Versus Transfemoral Access for Woven EndoBridge (WEB) Embolization of Intracranial Aneurysms: A Propensity-Score Matched Multicenter Study (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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35. The Woven EndoBridge (WEB) device for the treatment of Intracranial Aneurysms: A Decade of Lessons Learned and Changes in Practice from the WorldwideWEB Consortium (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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36. Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H, additional, Sweid, Ahmad, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna L, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Brehm, Alex, additional, MohammedAli, MajdEddin, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Stapleton, Christopher J, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
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38. Retreatment of Residual and Recurrent Aneurysms After Embolization With the Woven EndoBridge Device: Multicenter Case Series

Author

Srinivasan, Visish M., primary, Dmytriw, Adam A., additional, Regenhardt, Robert W., additional, Vicenty-Padilla, Juan, additional, Alotaibi, Naif M., additional, Levy, Elad, additional, Waqas, Muhammad, additional, Cherian, Jacob, additional, Johnson, Jeremiah N., additional, Jabbour, Pascal, additional, Sweid, Ahmad, additional, Gross, Bradley, additional, Starke, Robert M., additional, Puri, Ajit, additional, Massari, Francesco, additional, Griessenauer, Christoph J., additional, Catapano, Joshua S., additional, Rutledge, Caleb, additional, Tanweer, Omar, additional, Yashar, Parham, additional, Cortez, Gustavo M., additional, Aziz-Sultan, Mohammad A., additional, Patel, Aman B., additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Hanel, Ricardo A., additional, Lawton, Michael T., additional, and Kan, Peter, additional

Published
2022
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40. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Diestro, Jose Danilo Bengzon, additional, Dibas, Mahmoud, additional, Phan, Kevin, additional, Sweid, Ahmad, additional, Cuellar-Saenz, Hugo H., additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Sundararajan, Sri Hari, additional, Carnevale, Joseph, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Harker, Pablo, additional, Rabinov, James D., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Abbas, Rawad, additional, Inoue, Yasuaki, additional, Capirossi, Carolina, additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Regenhardt, Robert W., additional, Ghozy, Sherief, additional, Alotaibi, Naif M., additional, Tjoumakaris, Stavropoula, additional, Starke, Robert M., additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Ulfert, Christian, additional, Asadi, Hamed, additional, Brooks, Mark, additional, Maingard, Julian, additional, Jhamb, Ashu, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Savardekar, Amey, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Limbucci, Nicola, additional, Chen, Karen S., additional, Aziz-Sultan, Mohammad A., additional, Stapleton, Christopher J., additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Adeeb, Nimer, additional

Published
2022
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42. Contributors

Author

Ahmed, S. Uzair, Albuquerque, Felipe C., Amar, Arun Paul, Amllay, Abdelaziz, Antonios, Joseph P., Apuzzo, Michael L.J., Atalay, Yahya B., Ayub, Muhammad Abubakar, Aziz-Sultan, Mohammad A., Barros, Guilherme, Barrow, Daniel L., Bernardo, Antonio, Boddu, Srikanth, Bolar, Divya S., Caplan, Justin M., Carnevale, Joseph A., Carroll, Kate T., Catapano, Joshua S., Chen, Ching-Jen, Sander Connolly, E., Jr., David, Carlos A., Desai, Milli J., Dodd, William, Dornbos, David, III, Dowd, Richard S., Faramand, Andrew, Fejleh, Ashley, Flickinger, John C., Fraser, Justin F., Friedlander, Robert M., Garton, Andrew L.A., Ghannam, Moleca, Giantini-Larsen, Alexandra M., Goldberg, Jacob L., Goutnik, Michael, Gross, Bradley A., Hardigan, Trevor, Hoh, Brian L., Howard, Brian M., Hsiao, Albert, Huang, Judy, Jackson, Christopher M., Kano, Hideyuki, Karanjia, Navaz, Khalessi, Alexander A., Kim, Jennifer E., Kim, Louis J., Knopman, Jared, Kocharian, Gary, Lai, Pui Man Rosalind, Lam, Arthur M., Lamorie-Foote, Krista, Lang, Michael J., Laurent, Dimitri, Lawton, Michael T., Lee, Hubert, Lemkuil, Brian P., Levy, Elad I., Lucke-Wold, Brandon, Lunsford, L. Dade, Mack, William, Matouk, Charles C., McCarthy, David J., Meyer, R. Michael, Mocco, J, Mouchtouris, Nikolaos, Murthy, Santosh B., Niranjan, Ajay, Nistal, Dominic A., Norbash, Alexander, Ogilvy, Christopher S., Oh, S. Paul, Pannell, J. Scott, Patel, Aman B., Rahmani, Redi, Ramos, Alexander D., Regenhardt, Robert W., Renedo, Daniela, Rosenwasser, Robert H., Roytman, Michelle, Russin, Jonathan, Salem, Mohamed M., Scherschinski, Lea, Schwarz, Justin, Sekhar, Laligam N., Sen, Rajeev D., Sheehan, Jason P., Shenoy, Varadaraya S., Siddiqui, Adnan H., Sizdahkhani, Saman, Small, Coulter Nathan, Soman, Salil, Souweidane, Mark M., Spinazzi, Eleonora F., Srinivas, Shanmukha, Srinivasan, Visish M., Steinberg, Gary K., Stieg, Philip E., Sujijantarat, Nanthiya, Sweid, Ahmad, Tahir, Rizwan, Tamargo, Rafael J., Tjoumakaris, Stavropoula, Tsiouris, Apostolos John, Vranic, Justin E., Wali, Arvin R., Waqas, Muhammad, White, Halina, Xu, Risheng, Yachnis, Anthony T., Yaeger, Kurt, Yun, Jonathan J., and Zetchi, Akli

Published
2024
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44. Experience With the Pipeline Embolization Device for Posterior Circulations Aneurysms: A Multicenter Cohort Study

Author

Griessenauer, Christoph J, primary, Enriquez-Marulanda, Alejandro, additional, Taussky, Philipp, additional, Biswas, Arundhati, additional, Grandhi, Ramesh, additional, Xiang, Sissi, additional, Hong, Tao, additional, Rinaldo, Lorenzo, additional, Lanzino, Giuseppe, additional, Brinjikji, Waleed, additional, Burkhardt, Jan-Karl, additional, Kan, Peter, additional, Ghuman, Mandeep, additional, Yang, Victor X D, additional, Chen, Karen, additional, Aziz-Sultan, Mohammad A, additional, Ghorbani, Mohammad, additional, Schirmer, Clemens M, additional, Goren, Oded, additional, Dalal, Shamsher S, additional, Killer-Oberpfalzer, Monika, additional, Müller-Thies-Broussalis, Erasmia, additional, Koch, Matthew J, additional, Stapleton, Christopher J, additional, Patel, Aman B, additional, Foreman, Paul M, additional, Cress, Marshall C, additional, Hirschl, Robert A, additional, Krings, Timo, additional, Zhang, Hongqi, additional, and Dmytriw, Adam A, additional

Published
2021
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50. Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Author

Adeeb, Nimer, Dibas, Mahmoud, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H, Sweid, Ahmad, Lay, Sovann V, Guenego, Adrien, Aslan, Assala, Renieri, Leonardo, Sundararajan, Sri Hari, Saliou, Guillaume, Mo¨hlenbruch, Markus, Regenhardt, Robert W, Vranic, Justin E, Lylyk, Ivan, Foreman, Paul M, Vachhani, Jay A, Župančić, Vedran, Hafeez, Muhammad U, Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M, Rabinov, James D, Ren, Yifan, Schirmer, Clemens M, Piano, Mariangela, Kuhn, Anna L, Michelozzi, Caterina, Elens, Stephanie, Starke, Robert M, Hassan, Ameer, Salehani, Arsalaan, Brehm, Alex, MohammedAli, MajdEddin, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S, Pero, Guglielmo, Griessenauer, Christoph J, Asadi, Hamed, Siddiqui, Adnan, Ducruet, Andrew, Albuquerque, Felipe C, Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Stapleton, Christopher J, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A, Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, Patel, Aman B, and Dmytriw, Adam A

Abstract

BackgroundThe Woven EndoBridge (WEB) device has Food and Drug Administration approval for treatment of wide-necked intracranial bifurcation aneurysms. The WEB device has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes.ObjectiveTo compare angiographic and clinical outcomes after treatment of bifurcation aneurysms at various locations, including anterior communicating artery (AComA), anterior cerebral artery (ACA) bifurcation distal to AComA, basilar tip, internal carotid artery (ICA) bifurcation, and middle cerebral artery (MCA) bifurcation aneurysms using the WEB device.MethodsA retrospective cohort analysis was conducted at 22 academic institutions worldwide to compare treatment outcomes of patients with intracranial bifurcation aneurysms using the WEB device. Data include patient and aneurysm characteristics, procedural details, angiographic and functional outcomes, and complications.ResultsA total of 572 aneurysms were included. MCA (36%), AComA (35.7%), and basilar tip (18.9%) aneurysms were most common. The rate of adequate aneurysm occlusion was significantly higher for basilar tip (91.6%) and ICA bifurcation (96.7%) aneurysms and lower for ACA bifurcation (71.4%) and AComA (80.6%) aneurysms (p=0.04).ConclusionTo our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.

Published
2023
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