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128 results on '"Azzena B"'

1. Total level and release of silver from a nanoparticles containing dressing used in burns care – a pilot study

Author

Rigo C., Roman M., Munivrana I., Vindigni V., Azzena B., Barbante C., and Cairns W. R. L.

Subjects
Silver, Burns, ICP-MS, isotope dilution analysis, SEM-E, Environmental sciences, GE1-350
Abstract

For centuries silver and its compounds have been in use to control infection and avoid septicaemia in the care of burns and chronic wounds. Renewed interest has resulted in a number of silver-based dressings exploiting nanotechnology that are now widely employed in burns centers. Despite extensive use, a systematic study of the chemical composition, release kinetics and biochemical action of these products has yet to be published. In this work we have characterized the morphology and elemental composition of a commercial dressings containing Ag by SEM-EDS. The silver content was determined by ICP-MS to be about 1.4 mg cm-2. Release kinetics in ultra pure water, physiological saline solution and human serum substitute were then deeply investigated. The highest release rates were found in serum substitute, with a maximum of 2.6 μg hr-1 cm-2. Our results show that the mean inhibitory concentrations are exceeded for most common pathogens in serum substitute and sterile water, while the presence of high Cllevels inactivates the dressings.

Published
2013
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10. Late complications of high-voltage electrical injury might involve multiple systems and be related to current path

Author

Azzena, B., Tocco-Tussardi, I., Pontini, A., Presman, B., and Huss, F.

Subjects
Research Article
Abstract

Delayed complications of electrical burns are mostly unexpected, and the link between the injury and the symptoms often goes unrecognized. A possible relation between source-ground sites and late clinical manifestations was recently emphasized. We report a unique case of combined intestinal-spinal delayed complications following a high-voltage electrical injury, a possible explanation being a greater current flow through the right hemisoma. The potential for late complications is an additional feature that physicians must consider in managing electrical injuries. Manifestations are variable and presentation is confounding, but current flow path can constitute a precious source of information to predict complications in the late phase of management.Les complications tardives des électrisations par haut voltage sont le plus souvent inattendues et le lien avec l’accident initial est fréquemment non reconnu. Une relation possible entre le trajet source-terre et les complications tardives a récemment été mise en évidence. Nous rapportons le cas de complication tardive touchant à la fois l’intestin et la moëlle épinière, pouvant être expliqué par le passage préférentiel du courant dans l’hémicorps droit. La possibilité de complications tardives doit être prise en compte des électrisations par haut voltage. Ces manifestations sont variables et la clinique peut être peu claire, mais le trajet supposé du courant peut être un argument permettant de relier l’atteinte initiale et les complications tardives.

Published
2016

11. Late complications of high-voltage electrical injury might involve multiple systems and be related to current path

Author

Azzena, B, Tocco-Tussardi, I, Pontini, A, Presman, B, Huss, Fredrik, Azzena, B, Tocco-Tussardi, I, Pontini, A, Presman, B, and Huss, Fredrik

Abstract

SUMMARY Delayed complications of electrical burns are mostly unexpected, and the link between the injury and the symptoms oftengoes unrecognized. A possible relation between source-ground sites and late clinical manifestations was recently emphasized. We report aunique case of combined intestinal-spinal delayed complications following a high-voltage electrical injury, a possible explanation being agreater current flow through the right hemisoma. The potential for late complications is an additional feature that physicians must considerin managing electrical injuries. Manifestations are variable and presentation is confounding, but current flow path can constitute a precioussource of information to predict complications in the late phase of management.

Published
2016

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