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4 results on '"B Y, Cooper"'

1. Combinations of classical and non-classical voltage dependent potassium channel openers suppress nociceptor discharge and reverse chronic pain signs in a rat model of Gulf War illness

Author

B Y, Cooper, T J, Nutter, L D, Flunker, and C M, Bowers

Subjects
Dacarbazine, Meclofenamic Acid, Diclofenac, Potassium Channels, Ganglia, Spinal, General Neuroscience, Animals, Nociceptors, Persian Gulf Syndrome, Chronic Pain, Toxicology, Rats
Abstract

In a companion paper we examined whether combinations of K

Published
2022

2. Development of KVO treatment strategies for chronic pain in a rat model of Gulf War Illness

Author

L K, Flunker, T J, Nutter, C M, Bowers, and B Y, Cooper

Subjects
Male, Neurons, Pharmacology, Analgesics, Diclofenac, KCNQ Potassium Channels, Oxotremorine, Anti-Inflammatory Agents, Non-Steroidal, Action Potentials, Phenylenediamines, Toxicology, Rats, Rats, Sprague-Dawley, Gene Expression Regulation, Ganglia, Spinal, Animals, Persian Gulf Syndrome, Carbamates, Chronic Pain
Abstract

We examined whether combinations of K

Published
2022

4. Aging effects on the perception of noxious and non-noxious thermal stimuli applied to the face

Author

B. Y. Cooper, Marc W. Heft, R. O’Brien, K. K. O’Brien, and E. Hemp

Subjects
Adult, Male, Pain Threshold, medicine.medical_specialty, Aging, Hot Temperature, media_common.quotation_subject, Sensory system, Audiology, behavioral disciplines and activities, Developmental psychology, Thermal stimulation, Sex Factors, Sensory threshold, Perception, Threshold of pain, medicine, Psychophysics, Pain perception, Humans, media_common, Aged, Aged, 80 and over, Middle Aged, Chin, medicine.anatomical_structure, Sensory Thresholds, Female, sense organs, Geriatrics and Gerontology, Psychology, psychological phenomena and processes
Abstract

While age-related sensory deficits have been demonstrated for the senses of vision, audition, and the chemical senses, reports have differed with regard to changes in painful and non-painful thermal sensation. One hundred and seventy-nine healthy, community-dwelling individuals aged 20-89 years rated threshold and suprathreshold warming, cooling, and painful stimuli delivered to glabrous (upper lip) and hairy (chin) sites of the face in three separate testing sessions. Threshold measures were determined by the Method of Limits. Suprathreshold stimuli were assessed by a cross-modality matching procedure and a Pooled Adjacent Violators Algorithm-based analysis. The analyses of the effect of age on the threshold and suprathreshold measures of sensory performance yielded disparate findings. There are modest changes in warming and cooling perception with increased age, but pain perception is relatively unaffected. There is a slight diminution in threshold and suprathreshold thermal performance with increasing aging.

Published
1996

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