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586 results on '"BANCROFT, A. J."'

3. Defining the early stages of intestinal colonisation by whipworms

Author

Duque-Correa, María A., Goulding, David, Rodgers, Faye H., Gillis, J. Andrew, Cormie, Claire, Rawlinson, Kate A., Bancroft, Allison J., Bennett, Hayley M., Lotkowska, Magda E., Reid, Adam J., Speak, Anneliese O., Scott, Paul, Redshaw, Nicholas, Tolley, Charlotte, McCarthy, Catherine, Brandt, Cordelia, Sharpe, Catherine, Ridley, Caroline, Moya, Judit Gali, Carneiro, Claudia M., Starborg, Tobias, Hayes, Kelly S., Holroyd, Nancy, Sanders, Mandy, Thornton, David J., Grencis, Richard K., and Berriman, Matthew

Published
2022
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6. Where is my hand? Proprioceptive disturbances in posterior cortical atrophy and typical Alzheimer’s disease

Author

Yong, Keir X X, primary, Bancroft, Matthew J, additional, Bai, Yuhan, additional, Hayes, Oliver S, additional, Mahendran, Sharveena, additional, Ocal, Dilek, additional, Brotherhood, Emilie V, additional, Hoe, Juanita, additional, Kaski, Diego, additional, Pisella, Laure, additional, Crutch, Sebastian J, additional, and Day, Brian L, additional

Published
2023
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7. Do Pretests Increase Student Achievement as Measured by Posttests?

Author

Bancroft, Roger J.

Abstract

This report describes a study of the effects of using pretests in science classes on chapter test achievement results. The targeted population consisted of eighth grade science students at a junior high school from 1992 to 2001. Whether giving a pretest followed by a posttest at the end of the chapter, or giving only the test at chapter end resulted in superior class averages was investigated. Results show that in all cases giving pretests increased the score on the posttest over the use of the posttest only. A statistical analysis was performed to detect any difference in science test averages for the targeted groups. In three subject areas (Genetics, Chemical Families, and Rocks and Minerals), the null hypothesis was rejected; giving a pretest did increase achievement. For one additional topic, the null hypothesis was supported; the pretest did not increase the achievement score in comparison with the results from posttest alone. It is recommended that the use of the pretest/posttest format be followed, with the objective being a positive effect on student achievement as measured by the Illinois Goals Assessment Test. (Contains 11 tables and 23 references.) (Author/SLD)

Published
2001

9. Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei

Author

Tippayawat, Patcharaporn, Saenwongsa, Wipawee, Mahawantung, Jirawan, Suwannasaen, Duangchan, Chetchotisakd, Ploenchan, Limmathurotsakul, Direk, Peacock, Sharon J, Felgner, Philip L, Atkins, Helen S, Titball, Richard W, Bancroft, Gregory J, and Lertmemongkolchai, Ganjana

Subjects
gamma-interferon, ifn-gamma, provides protection, severe melioidosis, adaptive immunity, secretion system, murine model, risk-factors, infection, identification
Abstract

Background: Infection with the Gram-negative bacterium Burkholderia pseudomallei is an important cause of community-acquired lethal sepsis in endemic regions in southeast Asia and northern Australia and is increasingly reported in other tropical areas. In animal models, production of interferon-gamma (IFN-gamma) is critical for resistance, but in humans the characteristics of IFN-gamma production and the bacterial antigens that are recognized by the cell-mediated immune response have not been defined. Methods: Peripheral blood from 133 healthy individuals who lived in the endemic area and had no history of melioidosis, 60 patients who had recovered from melioidosis, and 31 other patient control subjects were stimulated by whole bacteria or purified bacterial proteins in vitro, and IFN-gamma responses were analyzed by ELISPOT and flow cytometry. Findings: B. pseudomallei was a potent activator of human peripheral blood NK cells for innate production of IFN-gamma. In addition, healthy individuals with serological evidence of exposure to B. pseudomallei and patients recovered from active melioidosis developed CD4(+) (and CD8(+)) T cells that recognized whole bacteria and purified proteins LolC, OppA, and PotF, members of the B. pseudomallei ABC transporter family. This response was primarily mediated by terminally differentiated T cells of the effector-memory (T(EMRA)) phenotype and correlated with the titer of anti-B. pseudomallei antibodies in the serum. Conclusions: Individuals living in a melioidosis-endemic region show clear evidence of T cell priming for the ability to make IFN-gamma that correlates with their serological status. The ability to detect T cell responses to defined B. pseudomallei proteins in large numbers of individuals now provides the opportunity to screen candidate antigens for inclusion in protein or polysaccharide-conjugate subunit vaccines against this important but neglected disease.

Published
2009

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